Application of an adenoviral vector encoding soluble transforming growth factor-β type II receptor to the treatment of diabetic nephropathy in mice

Clinical and Experimental Pharmacology and Physiology

Volumn 35, Issue 11, 2008, Pages 1288-1293

  Kondo, Takehito ^a   Takemura, Genzou ^a   Kosai, Ken Ichiro ^b   Ohno, Takamasa ^a   Takahashi, Tomoyuki ^b   Esaki, Masayasu ^a   Goto, Kazuko ^a   Maruyama, Rumi ^a   Murata, Ichijiro ^a   Minatoguchi, Shinya ^a   Fujiwara, Takako ^c   Fujiwara, Hisayoshi ^a  

^a GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KURUME UNIVERSITY   (Japan)

^c KYOTO WOMEN'S UNIVERSITY   (Japan)

Author keywords

Diabetes; Fibrosis; Gene therapy; Nephropathy; Transforming growth factor

Indexed keywords

ADENOVIRUS VECTOR; ALPHA SMOOTH MUSCLE ACTIN; BETA GALACTOSIDASE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2;

ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DRUG BLOOD LEVEL; FEMALE; GENE EXPRESSION; GLOMERULONEPHRITIS; GLUCOSE METABOLISM; KIDNEY CELL; KIDNEY FIBROSIS; KIDNEY FUNCTION; KIDNEY TUBULE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; STREPTOZOCIN DIABETES; SURVIVAL RATE; TREATMENT OUTCOME; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

ADENOVIRIDAE; ANIMALS; CHICKENS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DISEASE MODELS, ANIMAL; FEMALE; GENE THERAPY; GENETIC VECTORS; HUMANS; MICE; MICE, INBRED C57BL; PROTEIN-SERINE-THREONINE KINASES; RABBITS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SOLUBILITY; TRANSFORMING GROWTH FACTOR BETA;

EID: 54249093297     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2008.04967.x     Document Type: Article

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