Systemic administration of naked plasmid encoding hepatocyte growth factor ameliorates chronic renal fibrosis in mice

Gene Therapy

Volumn 8, Issue 19, 2001, Pages 1470-1479

  Yang, J ^a   Dai, C ^a   Liu, Y ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

C met; Chronic renal disease; Gene therapy; HGF; Renal fibrosis; UUO

Indexed keywords

ACTIN; COLLAGEN TYPE 1; CYTOKINE; FIBRONECTIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTRANSFERASE; PLASMID DNA; PLASMID VECTOR; SCATTER FACTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL MODEL; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DISEASE COURSE; DRUG ADMINISTRATION ROUTE; DRUG ISOLATION; DRUG TISSUE LEVEL; ENZYME ACTIVATION; GENE REPRESSION; GENE TARGETING; GENE TRANSFER; GENETIC CODE; IN VIVO STUDY; INCIDENCE; KIDNEY FAILURE; KIDNEY FIBROSIS; KIDNEY INTERSTITIUM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE; TREATMENT PLANNING; URETER OBSTRUCTION;

ACTINS; ANIMALS; BLOTTING, WESTERN; CHRONIC DISEASE; COLLAGEN; DNA; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBRONECTINS; FIBROSIS; GENE EXPRESSION; GENE THERAPY; HEPATOCYTE GROWTH FACTOR; KIDNEY FAILURE, CHRONIC; MALE; MICE; MICE, INBRED STRAINS; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, ANIMAL; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA;

EID: 0034782480     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301545     Document Type: Article

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