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Volumn 1, Issue , 2006, Pages 349-374

Pathogenesis of nonimmune glomeralopathies

Author keywords

Alport syndrome; Glomerular basement membrane; Glomerulosclerosis; Podocyte; Slit diaphragm

Indexed keywords

ALPHA ACTININ; ANGIOTENSIN; CD2 ASSOCIATED PROTEIN; LAMININ; NEPHRIN; PLATELET DERIVED GROWTH FACTOR; PODOCIN; SLIT PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSIENT RECEPTOR POTENTIAL CHANNEL; VASCULOTROPIN; BIOLOGICAL MARKER;

EID: 33645733358     PISSN: 15534006     EISSN: 15534014     Source Type: Book Series    
DOI: 10.1146/annurev.pathol.1.110304.100119     Document Type: Review
Times cited : (59)

References (124)
  • 2
    • 0003104549 scopus 로고
    • The role of podocytes in the development of glomerular sclerosis
    • Kriz W, Elger M, Nagata M, Kretzler M, Uiker S, et al. 1994. The role of podocytes in the development of glomerular sclerosis. Kidney Int. 45:S64-S72
    • (1994) Kidney Int. , vol.45
    • Kriz, W.1    Elger, M.2    Nagata, M.3    Kretzler, M.4    Uiker, S.5
  • 3
    • 0035123317 scopus 로고    scopus 로고
    • Tracer studies in the rat demonstrate misdirected filtration and peritubular filtrate spreading in nephrons with segmental glomerulosclerosis
    • Kriz W, Hartmann I, Hosser H, Hahnel B, Kranzlin B, et al. 2001. Tracer studies in the rat demonstrate misdirected filtration and peritubular filtrate spreading in nephrons with segmental glomerulosclerosis. J. Am. Soc. Nephrol. 12:496-506
    • (2001) J. Am. Soc. Nephrol. , vol.12 , pp. 496-506
    • Kriz, W.1    Hartmann, I.2    Hosser, H.3    Hahnel, B.4    Kranzlin, B.5
  • 5
    • 0029116262 scopus 로고
    • Endothelial cell injury initiates glomerular sclerosis in the rat remnant kidney
    • Lee LK, Meyer TW, Pollock AS, Lovett DH. 1995. Endothelial cell injury initiates glomerular sclerosis in the rat remnant kidney. J. Clin. Invest. 96:953-64
    • (1995) J. Clin. Invest. , vol.96 , pp. 953-964
    • Lee, L.K.1    Meyer, T.W.2    Pollock, A.S.3    Lovett, D.H.4
  • 6
    • 0031870338 scopus 로고    scopus 로고
    • Apoptosis in glomerular endothelial cells during the development of glomerulosclerosis in the remnant kidney model
    • Kitamura H, Shimizu A, Masuda Y, Ishikazi M, Sugisaki Y, et al. 1998. Apoptosis in glomerular endothelial cells during the development of glomerulosclerosis in the remnant kidney model. Exp. Nephrol. 6:328-36
    • (1998) Exp. Nephrol. , vol.6 , pp. 328-336
    • Kitamura, H.1    Shimizu, A.2    Masuda, Y.3    Ishikazi, M.4    Sugisaki, Y.5
  • 7
    • 0026541019 scopus 로고
    • Glomerular cell proliferation and PDGF expression precede glomerular sclerosis in the rat remnant kidney model
    • Floege J, Burns MW, Alpers CE, Yoshimura A, Pritzl P, et al. 1992. Glomerular cell proliferation and PDGF expression precede glomerular sclerosis in the rat remnant kidney model. Kidney Int. 41:297-309
    • (1992) Kidney Int. , vol.41 , pp. 297-309
    • Floege, J.1    Burns, M.W.2    Alpers, C.E.3    Yoshimura, A.4    Pritzl, P.5
  • 8
    • 0034034757 scopus 로고    scopus 로고
    • NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid resistant nephrotic syndrome
    • Boute N, Gribouval O, Boute N, Sich M, Benessy F, et al. 2000. NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid resistant nephrotic syndrome. Nat. Genet. 24:349-54
    • (2000) Nat. Genet. , vol.24 , pp. 349-354
    • Boute, N.1    Gribouval, O.2    Boute, N.3    Sich, M.4    Benessy, F.5
  • 9
    • 0034051681 scopus 로고    scopus 로고
    • Mutations in ACTN4, encoding alpha actinin 4, cause familial focal segmental glomerulosclerosis
    • Kaplan JM, Kim SH, North KN, Rennke H, Correia LA, et al. 2001. Mutations in ACTN4, encoding alpha actinin 4, cause familial focal segmental glomerulosclerosis. Nat. Genet. 24:251-56
    • (2001) Nat. Genet. , vol.24 , pp. 251-256
    • Kaplan, J.M.1    Kim, S.H.2    North, K.N.3    Rennke, H.4    Correia, L.A.5
  • 10
    • 0033536599 scopus 로고    scopus 로고
    • Congenital nephrotic syndrome in mice lacking CD2-associated protein
    • Shih NY, Li J, Karpitskii V, Nguyen A, Dustin ML, et al. 1999. Congenital nephrotic syndrome in mice lacking CD2-associated protein. Science 286:312-15
    • (1999) Science , vol.286 , pp. 312-315
    • Shih, N.Y.1    Li, J.2    Karpitskii, V.3    Nguyen, A.4    Dustin, M.L.5
  • 11
    • 0034917262 scopus 로고    scopus 로고
    • Impaired angiogenesis in the rat remnant kidney model. Administration of VEGF reduces renal fibrosis and stabilizes renal function
    • Kang DH, Hughes J, Mazzali M, Schreiner GF, Johnson RJ. 2001. Impaired angiogenesis in the rat remnant kidney model. Administration of VEGF reduces renal fibrosis and stabilizes renal function. J. Am. Soc. Nephrol. 12:1448-57
    • (2001) J. Am. Soc. Nephrol. , vol.12 , pp. 1448-1457
    • Kang, D.H.1    Hughes, J.2    Mazzali, M.3    Schreiner, G.F.4    Johnson, R.J.5
  • 12
    • 0032710966 scopus 로고    scopus 로고
    • Podocyte number predicts long term urinary albumin excretion in Pima Indians with type II diabetes and microalbuminuria
    • Meyer TW, Bennett PH, Nelson RG. 1999. Podocyte number predicts long term urinary albumin excretion in Pima Indians with type II diabetes and microalbuminuria. Diabetilogia 42:1341-44
    • (1999) Diabetilogia , vol.42 , pp. 1341-1344
    • Meyer, T.W.1    Bennett, P.H.2    Nelson, R.G.3
  • 14
    • 0001363498 scopus 로고
    • Nephron adaptation to renal injury or ablation
    • Brenner BM. 1985. Nephron adaptation to renal injury or ablation. Am. J. Physiol. Renal Physiol. 249:F324-F337
    • (1985) Am. J. Physiol. Renal Physiol. , vol.249
    • Brenner, B.M.1
  • 15
    • 17644444238 scopus 로고    scopus 로고
    • Transforming growth factor beta is upregulated by podocytes in response to excess intraglomerular passage of proteins: A central pathway in progressive glomerulosclerosis
    • Abbate M, Zoja C, Morigi M, Rottoli D, Angioletti S, et al. 2002. Transforming growth factor beta is upregulated by podocytes in response to excess intraglomerular passage of proteins: a central pathway in progressive glomerulosclerosis. Am. J. Pathol. 161:2179-93
    • (2002) Am. J. Pathol. , vol.161 , pp. 2179-2193
    • Abbate, M.1    Zoja, C.2    Morigi, M.3    Rottoli, D.4    Angioletti, S.5
  • 16
    • 0030357278 scopus 로고    scopus 로고
    • Expression of vascular permeability factor (VEGF) is altered in many glomerular diseases
    • Shulman K, Rosen S, Tognazzi K, Manseau EJ, Brown LF. 1996. Expression of vascular permeability factor (VEGF) is altered in many glomerular diseases. J. Am. Soc. Nephrol. 7:661-66
    • (1996) J. Am. Soc. Nephrol. , vol.7 , pp. 661-666
    • Shulman, K.1    Rosen, S.2    Tognazzi, K.3    Manseau, E.J.4    Brown, L.F.5
  • 17
    • 0031756766 scopus 로고    scopus 로고
    • From segmental glomerulosclerosis to total nephron degeneration and interstitial fibrosis: A histopathological study in rat models and human glomerulopathies
    • Kriz W, Hosser H, Hahnel B, Gretz N, Provoost AP. 1998. From segmental glomerulosclerosis to total nephron degeneration and interstitial fibrosis: A histopathological study in rat models and human glomerulopathies. Nephrol. Dial. Transplant. 13:2781-98
    • (1998) Nephrol. Dial. Transplant. , vol.13 , pp. 2781-2798
    • Kriz, W.1    Hosser, H.2    Hahnel, B.3    Gretz, N.4    Provoost, A.P.5
  • 18
    • 33645728747 scopus 로고    scopus 로고
    • note
    • Deleted in proof
  • 19
    • 0007617245 scopus 로고
    • How does glomerular epithelial cell injury contribute to progressive glomerular damage?
    • Rennke HG. 1994. How does glomerular epithelial cell injury contribute to progressive glomerular damage? Kidney Int. 45:S58-S63
    • (1994) Kidney Int. , vol.45
    • Rennke, H.G.1
  • 20
    • 16644365383 scopus 로고    scopus 로고
    • Podocytes are firmly attached to glomerular basement membrane in kidneys with heavy proteinuria
    • Lahdenkari AT, Lounatmaa K, Patrakka J, Holmberg C, Wartiovaara J, et al. 2004. Podocytes are firmly attached to glomerular basement membrane in kidneys with heavy proteinuria. Am. Soc. Nephrol. 15:2611-18
    • (2004) Am. Soc. Nephrol. , vol.15 , pp. 2611-2618
    • Lahdenkari, A.T.1    Lounatmaa, K.2    Patrakka, J.3    Holmberg, C.4    Wartiovaara, J.5
  • 22
    • 0015953201 scopus 로고
    • Porous substructure of the glomerular slit diaphragm in the rat and mouse
    • Rodewald R. 1974. Porous substructure of the glomerular slit diaphragm in the rat and mouse. J. Cell Biol. 60:423-33
    • (1974) J. Cell Biol. , vol.60 , pp. 423-433
    • Rodewald, R.1
  • 23
    • 0032015551 scopus 로고    scopus 로고
    • Positionaly cloned gene for a novel glomerular protein "nephrin" is mutated in congenital nephrotic syndrome
    • Kestila M, Lenkkeri U, Mannikko M, Lamerdin J, McCready P, et al. 1998. Positionaly cloned gene for a novel glomerular protein "nephrin" is mutated in congenital nephrotic syndrome. Mol. Cell. 1:575-82
    • (1998) Mol. Cell. , vol.1 , pp. 575-582
    • Kestila, M.1    Lenkkeri, U.2    Mannikko, M.3    Lamerdin, J.4    McCready, P.5
  • 24
    • 0037270882 scopus 로고    scopus 로고
    • NEPH1 defines a novel family of podocin interacting proteins
    • Sellin L, Huner TB, Gerke P, Quack I, Pavenstadt H, et al. 2003. NEPH1 defines a novel family of podocin interacting proteins. FASEB J. 17:115-17
    • (2003) FASEB J. , vol.17 , pp. 115-117
    • Sellin, L.1    Huner, T.B.2    Gerke, P.3    Quack, I.4    Pavenstadt, H.5
  • 25
    • 0034948819 scopus 로고    scopus 로고
    • Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to nephrin
    • Donoviel DB, Freed DD, Vogel H, Potter DG, Hawkins E, et al. 2001. Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to nephrin. Mol. Cell. Biol. 21:4829-36
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 4829-4836
    • Donoviel, D.B.1    Freed, D.D.2    Vogel, H.3    Potter, D.G.4    Hawkins, E.5
  • 26
    • 33645749205 scopus 로고    scopus 로고
    • Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography
    • Wartiovaara J, Ofverstedt LG, Khoshnoodi J, Zhang J, Makela E, et al. 2004. Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography. J. Clin. Invest. 10:475-1483
    • (2004) J. Clin. Invest. , vol.10 , pp. 475-1483
    • Wartiovaara, J.1    Ofverstedt, L.G.2    Khoshnoodi, J.3    Zhang, J.4    Makela, E.5
  • 27
    • 0035210324 scopus 로고    scopus 로고
    • Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin
    • Schwarz K, Simons M, Reiser J, Saleem MA, Faul C, et al. 2001. Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin. J. Clin. Invest. 108:1621-29
    • (2001) J. Clin. Invest. , vol.108 , pp. 1621-1629
    • Schwarz, K.1    Simons, M.2    Reiser, J.3    Saleem, M.A.4    Faul, C.5
  • 28
    • 0038788840 scopus 로고    scopus 로고
    • Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling
    • Huber TB, Hartleben B, Kim J, Schmidts M, Schermer B, et al. 2003. Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling. Mol. Cell. Biol. 23:4917-28
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 4917-4928
    • Huber, T.B.1    Hartleben, B.2    Kim, J.3    Schmidts, M.4    Schermer, B.5
  • 29
    • 0038819061 scopus 로고    scopus 로고
    • Mice deficient in alpha-actinin 4 have severe glomerular disease
    • Kos C, Le TC, Sinha S, Henderson JM, Kim SH, et al. 2003. Mice deficient in alpha-actinin 4 have severe glomerular disease. J. Clin. Invest. 111:1683-90
    • (2003) J. Clin. Invest. , vol.111 , pp. 1683-1690
    • Kos, C.1    Le, T.C.2    Sinha, S.3    Henderson, J.M.4    Kim, S.H.5
  • 32
    • 0033366679 scopus 로고    scopus 로고
    • Structure of the gene for congenital nephrotic syndrome of the Finnish type (NPHS1) and characterization of mutations
    • Lenkkeri U, Mannikko M, McCready P, Lamerdin J, Gribouval O, et al. 1999. Structure of the gene for congenital nephrotic syndrome of the Finnish type (NPHS1) and characterization of mutations. Am. J. Hum. Genet. 64:51-61
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 51-61
    • Lenkkeri, U.1    Mannikko, M.2    McCready, P.3    Lamerdin, J.4    Gribouval, O.5
  • 33
    • 0033855640 scopus 로고    scopus 로고
    • Congenital nephrotic syndrome (NPHS1): Features resulting from different mutations in Finnish patients
    • Pattrakka J, Kestila M, Wartiovaara J, Ruotsalainen V, Tissari P, et al. 2000. Congenital nephrotic syndrome (NPHS1): Features resulting from different mutations in Finnish patients. Kidney Int. 58:972-80
    • (2000) Kidney Int. , vol.58 , pp. 972-980
    • Pattrakka, J.1    Kestila, M.2    Wartiovaara, J.3    Ruotsalainen, V.4    Tissari, P.5
  • 34
    • 0035510132 scopus 로고    scopus 로고
    • Defective nephrin trafficking caused by missense mutations in the NPHSI gene: Insight into the mechanisms of congenital nephrotic syndrome
    • Liu L, Done SC, Khoshnoodi J, Bertorello A, Wartiovaara J, et al. 2001. Defective nephrin trafficking caused by missense mutations in the NPHSI gene: Insight into the mechanisms of congenital nephrotic syndrome. Hum. Mol. Genet. 10:2637-34
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2637-2734
    • Liu, L.1    Done, S.C.2    Khoshnoodi, J.3    Bertorello, A.4    Wartiovaara, J.5
  • 36
    • 0035164681 scopus 로고    scopus 로고
    • The murine nephrin gene is specifically expressed in kidney, brain, and pancreas. Inactivation of the gene leads to massive proteinuria and neonatal death
    • Putaala H, Soininen R, Kilpelainen P, Wartiovaara J, Tryggvason K. 2001. The murine nephrin gene is specifically expressed in kidney, brain, and pancreas. Inactivation of the gene leads to massive proteinuria and neonatal death. Hum. Mol. Genet. 10:1-8
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 1-8
    • Putaala, H.1    Soininen, R.2    Kilpelainen, P.3    Wartiovaara, J.4    Tryggvason, K.5
  • 38
    • 0036897388 scopus 로고    scopus 로고
    • NPHS2 mutations in late onset focal segmental glomerulosclerosis: R229Q is a common disease associated allele
    • Tsukaguchi H, Sudhakar A, Le TC, Nguyen T, Yao J, et al. 2002. NPHS2 mutations in late onset focal segmental glomerulosclerosis: R229Q is a common disease associated allele. J. Clin. Invest. 110:1654-66
    • (2002) J. Clin. Invest. , vol.110 , pp. 1654-1666
    • Tsukaguchi, H.1    Sudhakar, A.2    Le, T.C.3    Nguyen, T.4    Yao, J.5
  • 39
    • 0346121526 scopus 로고    scopus 로고
    • Molecular basis of the functional podocin-nephrin complex: Mutations in the NPHS2 gene disrupt nephrin targeting to the lipid raft microdomains
    • Huber TB, Simons M, Hartleben B, Semetz L, Schmidts M, et al. 2003. Molecular basis of the functional podocin-nephrin complex: mutations in the NPHS2 gene disrupt nephrin targeting to the lipid raft microdomains. Hum. Mol. Genet. 12:3397-3405
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 3397-3405
    • Huber, T.B.1    Simons, M.2    Hartleben, B.3    Semetz, L.4    Schmidts, M.5
  • 40
    • 11444261852 scopus 로고    scopus 로고
    • Disease-causing missense mutations in NPHS2 gene alter normal nephrin trafficking to the plasma membrane
    • Nishibori Y, Liu L, Hosoyamada M, Endou H, Kudo A, et al. 2004. Disease-causing missense mutations in NPHS2 gene alter normal nephrin trafficking to the plasma membrane. Kidney Int. 66:1755-65
    • (2004) Kidney Int. , vol.66 , pp. 1755-1765
    • Nishibori, Y.1    Liu, L.2    Hosoyamada, M.3    Endou, H.4    Kudo, A.5
  • 41
    • 0347986678 scopus 로고    scopus 로고
    • Early glomerular filtration defect and severe renal disease in podocin deficient mice
    • Roselli S, Heidet L, Sich M, Henger A, Kretzler M, et al. 2004. Early glomerular filtration defect and severe renal disease in podocin deficient mice. Mol. Cell. Biol. 24:550-60
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 550-560
    • Roselli, S.1    Heidet, L.2    Sich, M.3    Henger, A.4    Kretzler, M.5
  • 42
    • 0033789190 scopus 로고    scopus 로고
    • Actinin-4 is preferentially involved in circular ruffling and macropinocytosis in mouse macrophages
    • Araki N, Hatae T, Yamada T, Hirohashi S. 2000. Actinin-4 is preferentially involved in circular ruffling and macropinocytosis in mouse macrophages. J. Cell. Sci. 113:3329-40
    • (2000) J. Cell. Sci. , vol.113 , pp. 3329-3340
    • Araki, N.1    Hatae, T.2    Yamada, T.3    Hirohashi, S.4
  • 43
    • 16644399642 scopus 로고    scopus 로고
    • Alpha actinin 4 mediated FSGS: An inherited kidney disease caused by an aggregated and rapidly degraded cytoskeletal protein
    • Yao J, Le TC, Kos CH, Henderson JM, Allen PG, et al. 2004. Alpha actinin 4 mediated FSGS: An inherited kidney disease caused by an aggregated and rapidly degraded cytoskeletal protein. PLoS Biol. 2:787-94
    • (2004) PLoS Biol. , vol.2 , pp. 787-794
    • Yao, J.1    Le, T.C.2    Kos, C.H.3    Henderson, J.M.4    Allen, P.G.5
  • 44
    • 23844539615 scopus 로고    scopus 로고
    • CD2AP expression in podocytes rescues lethality of CD2AP deficiency
    • 43a. Grunkemeyer J, Kwoh C, Huber T, Shaw A. 2005. CD2AP expression in podocytes rescues lethality of CD2AP deficiency. J. Biol. Chem. 280(33):29677-81
    • (2005) J. Biol. Chem. , vol.280 , Issue.33 , pp. 29677-29681
    • Grunkemeyer, J.1    Kwoh, C.2    Huber, T.3    Shaw, A.4
  • 45
    • 0038136885 scopus 로고    scopus 로고
    • CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibility
    • Kim JM, Wu H, Green G, Winkler CA, Kopp JB, et al. 2003. CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibility. Science 300:1298-1300
    • (2003) Science , vol.300 , pp. 1298-1300
    • Kim, J.M.1    Wu, H.2    Green, G.3    Winkler, C.A.4    Kopp, J.B.5
  • 46
    • 4344685529 scopus 로고    scopus 로고
    • A novel role for the adapter molecule CD2 associated protein in TGF-B induced apoptosis
    • Schiffer M, Mundel P, Shaw AS, Bottinger EP. 2004. A novel role for the adapter molecule CD2 associated protein in TGF-B induced apoptosis. J. Biol. Chem. 279:37004-37012
    • (2004) J. Biol. Chem. , vol.279 , pp. 37004-37012
    • Schiffer, M.1    Mundel, P.2    Shaw, A.S.3    Bottinger, E.P.4
  • 47
    • 20844461826 scopus 로고    scopus 로고
    • A mutation in the TRPC6 cation channel causes familial segmental glomerulosclerosis
    • 45a. Winn MP, Conlon PJ, Lynn KL, Farrington MK, Creazzo T, et al. 2005. A mutation in the TRPC6 cation channel causes familial segmental glomerulosclerosis. Science 308:1801-4
    • (2005) Science , vol.308 , pp. 1801-1804
    • Winn, M.P.1    Conlon, P.J.2    Lynn, K.L.3    Farrington, M.K.4    Creazzo, T.5
  • 48
    • 22844436647 scopus 로고    scopus 로고
    • TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function
    • 45b. Reiser J, Polu KR, Moller CC, Kenlan P, Altintas MM, et al. 2005. TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat. Genet. 37:739-44
    • (2005) Nat. Genet. , vol.37 , pp. 739-744
    • Reiser, J.1    Polu, K.R.2    Moller, C.C.3    Kenlan, P.4    Altintas, M.M.5
  • 49
    • 0037075547 scopus 로고    scopus 로고
    • Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors
    • Soubeyran P. 2002. Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors. Nature 416:183-87
    • (2002) Nature , vol.416 , pp. 183-187
    • Soubeyran, P.1
  • 50
    • 0037743504 scopus 로고    scopus 로고
    • Fyn binds to and phosphorylates the slit diaphragm component nephrin
    • Verma R, Wharram B, Kovari I, Kunkel R, Nihalani D, et al. 2003. Fyn binds to and phosphorylates the slit diaphragm component nephrin. J. Biol. Chem. 278:20716-23
    • (2003) J. Biol. Chem. , vol.278 , pp. 20716-20723
    • Verma, R.1    Wharram, B.2    Kovari, I.3    Kunkel, R.4    Nihalani, D.5
  • 51
    • 9644273952 scopus 로고    scopus 로고
    • Src-family kinase fyn phosphorylates the cytoplasmic domain of nephrin and modulates it interaction with podocin
    • Li H, Lemay S, Aoudjit L, Kawachi H, Takano T. 2004. Src-family kinase fyn phosphorylates the cytoplasmic domain of nephrin and modulates it interaction with podocin. J. Am. Soc. Nephrol. 15:3006-15
    • (2004) J. Am. Soc. Nephrol. , vol.15 , pp. 3006-3015
    • Li, H.1    Lemay, S.2    Aoudjit, L.3    Kawachi, H.4    Takano, T.5
  • 53
    • 19944427728 scopus 로고    scopus 로고
    • Characterization of the interactions of the nephrin intracellular domain: Evidence that the scaffolding protein IQGAP1 associates with nephrin
    • Liu XL, Kilpelainen P, Hellman U, Sun Y, Wartiovaara J, et al. 2005. Characterization of the interactions of the nephrin intracellular domain: Evidence that the scaffolding protein IQGAP1 associates with nephrin. FEBS J. 272:228-43
    • (2005) FEBS J. , vol.272 , pp. 228-243
    • Liu, X.L.1    Kilpelainen, P.2    Hellman, U.3    Sun, Y.4    Wartiovaara, J.5
  • 54
    • 33645748408 scopus 로고    scopus 로고
    • Regulation of TRPC6 channel activity by tyrosine phosphorylation
    • 50a. Hisatsune C, Kuroda Y, Nakamura K, Inoue T, Nakamura T, et al. 2003. Regulation of TRPC6 channel activity by tyrosine phosphorylation. J. Biol. Chem. 278:20716-23
    • (2003) J. Biol. Chem. , vol.278 , pp. 20716-20723
    • Hisatsune, C.1    Kuroda, Y.2    Nakamura, K.3    Inoue, T.4    Nakamura, T.5
  • 56
    • 0021955669 scopus 로고
    • Glomerular podocytic injury in protein overload proteinuria
    • Davies D, Messina A, Thumwood CM, Ryan GB. 1985. Glomerular podocytic injury in protein overload proteinuria. Pathology 17:412-19
    • (1985) Pathology , vol.17 , pp. 412-419
    • Davies, D.1    Messina, A.2    Thumwood, C.M.3    Ryan, G.B.4
  • 59
    • 0028187129 scopus 로고
    • Introduction of a foreign gene into the kidney in vivo: Development of glomerulosclerosis by the transfection of gene for PDGF and TGF-β
    • Imai E, Isaka Y, Fujiwara Y, Kaneda Y, Kamada T, Ueda N. 1994. Introduction of a foreign gene into the kidney in vivo: Development of glomerulosclerosis by the transfection of gene for PDGF and TGF-β. Contrib. Nephrol. 107:205-15
    • (1994) Contrib. Nephrol. , vol.107 , pp. 205-215
    • Imai, E.1    Isaka, Y.2    Fujiwara, Y.3    Kaneda, Y.4    Kamada, T.5    Ueda, N.6
  • 61
    • 0035196183 scopus 로고    scopus 로고
    • Bone marrow is a reservoir of repopulating mesangial cells during glomerular remodeling
    • Ito T, Suzuki A, Imai E, Okabe M, Hori M. 2001. Bone marrow is a reservoir of repopulating mesangial cells during glomerular remodeling. J. Am. Soc. Nephrol. 12:2625-35
    • (2001) J. Am. Soc. Nephrol. , vol.12 , pp. 2625-2635
    • Ito, T.1    Suzuki, A.2    Imai, E.3    Okabe, M.4    Hori, M.5
  • 62
    • 0032814264 scopus 로고    scopus 로고
    • Type IV collagen and laminin regulate glomerular mesangial cell susceptibility to apoptosis via beta-1 integrin mediated survival signals
    • Mooney A, Jackson K, Bacon R, Streuli C, Edwards G, et al. 1999. Type IV collagen and laminin regulate glomerular mesangial cell susceptibility to apoptosis via beta-1 integrin mediated survival signals. Am. J. Pathol. 155:599-606
    • (1999) Am. J. Pathol. , vol.155 , pp. 599-606
    • Mooney, A.1    Jackson, K.2    Bacon, R.3    Streuli, C.4    Edwards, G.5
  • 64
    • 0942265458 scopus 로고    scopus 로고
    • Exogenous PDGF-D is a potent mesangial cell mitogen and causes a severe mesangial proliferative glomerulopathy
    • Hudkins KL, Gilbertson DG, Carling M, Taneda S, Hughes SD, et al. 2004. Exogenous PDGF-D is a potent mesangial cell mitogen and causes a severe mesangial proliferative glomerulopathy. J. Am. Soc. Nephrol. 15:286-98
    • (2004) J. Am. Soc. Nephrol. , vol.15 , pp. 286-298
    • Hudkins, K.L.1    Gilbertson, D.G.2    Carling, M.3    Taneda, S.4    Hughes, S.D.5
  • 65
    • 0346101489 scopus 로고    scopus 로고
    • Platelet derived growth factor plays a critical role to convert bone marrow cells into glomerular mesangial-like cells
    • Suzuki A, Iwatani H, Ito T, Imai E, Okabe M, et al. 2004. Platelet derived growth factor plays a critical role to convert bone marrow cells into glomerular mesangial-like cells. Kidney Int. 65:15-24
    • (2004) Kidney Int. , vol.65 , pp. 15-24
    • Suzuki, A.1    Iwatani, H.2    Ito, T.3    Imai, E.4    Okabe, M.5
  • 66
    • 0037370325 scopus 로고    scopus 로고
    • Glomerular specific alterations of VEGF-A expression lead to congenital and acquired glomerular disease
    • Eremina V, Sood M, Haigh J, Nagy A, Lajoie G, et al. 2003. Glomerular specific alterations of VEGF-A expression lead to congenital and acquired glomerular disease. J. Clin. Invest. 111:707-16
    • (2003) J. Clin. Invest. , vol.111 , pp. 707-716
    • Eremina, V.1    Sood, M.2    Haigh, J.3    Nagy, A.4    Lajoie, G.5
  • 67
    • 1642269792 scopus 로고    scopus 로고
    • ACE inhibition and at II antagonism in nondiabetic chronic nephropathies
    • Ruggenenti P. 2004. ACE inhibition and AT II antagonism in nondiabetic chronic nephropathies. Semin. Nephrol. 24:158-167
    • (2004) Semin. Nephrol. , vol.24 , pp. 158-167
    • Ruggenenti, P.1
  • 68
    • 0347992785 scopus 로고    scopus 로고
    • Activation of a local tissue angiotensin system in podocytes by mechanical strain
    • Durvasula RV, Petermann AT, Hiromura K, Blonski M, Pippin J, et al. 2004. Activation of a local tissue angiotensin system in podocytes by mechanical strain. Kidney Int. 65:30-39
    • (2004) Kidney Int. , vol.65 , pp. 30-39
    • Durvasula, R.V.1    Petermann, A.T.2    Hiromura, K.3    Blonski, M.4    Pippin, J.5
  • 69
    • 0030954434 scopus 로고    scopus 로고
    • Angiotensin II depolarizes podocyte in the intact glomerulus of the rat
    • Gloy J, Henger A, Fischer KG, Nitschke R, Mundel P, et al. 1997. Angiotensin II depolarizes podocyte in the intact glomerulus of the rat. J. Clin. Invest. 99:2772-81
    • (1997) J. Clin. Invest. , vol.99 , pp. 2772-2781
    • Gloy, J.1    Henger, A.2    Fischer, K.G.3    Nitschke, R.4    Mundel, P.5
  • 70
    • 0026951094 scopus 로고
    • Vasoactive substances induce cytoskeletal changes in cultured rat glomerular epithelial cells
    • Sharma R, Lovell HB, Wiegmann TB, Savin VJ. 1992. Vasoactive substances induce cytoskeletal changes in cultured rat glomerular epithelial cells. J. Am. Soc. Nephrol. 3:1131-38
    • (1992) J. Am. Soc. Nephrol. , vol.3 , pp. 1131-1138
    • Sharma, R.1    Lovell, H.B.2    Wiegmann, T.B.3    Savin, V.J.4
  • 72
    • 2542455650 scopus 로고    scopus 로고
    • Angiotensin II type I receptor overexpression in podocytes induces glomerulosclerosis in transgenic rats
    • Hoffmann S, Podlich D, Hahnel B, Kriz W, Gretz N. 2004. Angiotensin II type I receptor overexpression in podocytes induces glomerulosclerosis in transgenic rats. J. Am. Soc. Nephrol. 15:1475-87
    • (2004) J. Am. Soc. Nephrol. , vol.15 , pp. 1475-1487
    • Hoffmann, S.1    Podlich, D.2    Hahnel, B.3    Kriz, W.4    Gretz, N.5
  • 73
    • 0036100526 scopus 로고    scopus 로고
    • Replication and compartmentalization of HIV-1 in kidney epithelium in patients with HIV-associated nephropathy
    • Marras D, Bruggeman LA, Gao F, Tanji N, Mansukhani MM, et al. 2002. Replication and compartmentalization of HIV-1 in kidney epithelium in patients with HIV-associated nephropathy. Nat. Med. 8:522-26
    • (2002) Nat. Med. , vol.8 , pp. 522-526
    • Marras, D.1    Bruggeman, L.A.2    Gao, F.3    Tanji, N.4    Mansukhani, M.M.5
  • 74
    • 0026585698 scopus 로고
    • Human mesangial cells are resistant to multiple strains of human immuno deficiency virus strains 1 and 2
    • Alpers C, McClure J, Bürsten SL. 1992. Human mesangial cells are resistant to multiple strains of human immuno deficiency virus strains 1 and 2. Am. J. Kidney Dis. 19:126-30
    • (1992) Am. J. Kidney Dis. , vol.19 , pp. 126-130
    • Alpers, C.1    McClure, J.2    Bürsten, S.L.3
  • 75
    • 0026510175 scopus 로고
    • HIV infects glomerular endothelial and mesangial cells, but not epithelial cells in vitro
    • Green DF, Resnick L, Bourgoignie JJ. 1992. HIV infects glomerular endothelial and mesangial cells, but not epithelial cells in vitro. Kidney Int. 41:1956-60
    • (1992) Kidney Int. , vol.41 , pp. 1956-1960
    • Green, D.F.1    Resnick, L.2    Bourgoignie, J.J.3
  • 76
    • 0026007043 scopus 로고
    • HIV associated nephropathy in transgenic mice expressing HIV-1 genes
    • Dickie P, Felser J, Eckhaus M, Bryant J, Silver J, et al. 1991. HIV associated nephropathy in transgenic mice expressing HIV-1 genes. Virology 185:109-19
    • (1991) Virology , vol.185 , pp. 109-119
    • Dickie, P.1    Felser, J.2    Eckhaus, M.3    Bryant, J.4    Silver, J.5
  • 77
    • 1942518226 scopus 로고    scopus 로고
    • Focal glomerulosclerosis in proximal and c-fms transgenic mice links Vpr expression to HIV associated nephropathy
    • Dickie P, Roberts A, Uwiera R, Witmer J, Sharma K, Kopp JB. 2004. Focal glomerulosclerosis in proximal and c-fms transgenic mice links Vpr expression to HIV associated nephropathy. Virology 322:69-81
    • (2004) Virology , vol.322 , pp. 69-81
    • Dickie, P.1    Roberts, A.2    Uwiera, R.3    Witmer, J.4    Sharma, K.5    Kopp, J.B.6
  • 78
    • 4944222787 scopus 로고    scopus 로고
    • Nef stimulates proliferation of glomerular podocytes through activation of src dependent Stat3 and MAPK1,2 pathways
    • He JC, Husain M, Sunamoto M, D'Agati VD, Klotman ME, et al. 2004. Nef stimulates proliferation of glomerular podocytes through activation of src dependent Stat3 and MAPK1,2 pathways. J. Clin. Invest. 114:643-51
    • (2004) J. Clin. Invest. , vol.114 , pp. 643-651
    • He, J.C.1    Husain, M.2    Sunamoto, M.3    D'Agati, V.D.4    Klotman, M.E.5
  • 79
    • 0032929050 scopus 로고    scopus 로고
    • The dysregulated podocyte phenotype: A novel concept in the pathogenensis of collapsing idiopathic focal segmental glomerulosclerosis and HIV associated nephropathy
    • Barisoni L, Kriz W, Mundel P, D'Agati V. 1999. The dysregulated podocyte phenotype: a novel concept in the pathogenensis of collapsing idiopathic focal segmental glomerulosclerosis and HIV associated nephropathy. J. Am. Soc. Nephrol. 10:51-61
    • (1999) J. Am. Soc. Nephrol. , vol.10 , pp. 51-61
    • Barisoni, L.1    Kriz, W.2    Mundel, P.3    D'Agati, V.4
  • 80
    • 0031970078 scopus 로고    scopus 로고
    • Podocytes undergo phenotypic change and express macrophage-associated markers in idiopathic collapsing glomerulopathy
    • Bariety J, Nochy D, Mandet C, Jacquot C, Glotz D, Meyrier A. 1998. Podocytes undergo phenotypic change and express macrophage-associated markers in idiopathic collapsing glomerulopathy. Kidney Int. 53:918-25
    • (1998) Kidney Int. , vol.53 , pp. 918-925
    • Bariety, J.1    Nochy, D.2    Mandet, C.3    Jacquot, C.4    Glotz, D.5    Meyrier, A.6
  • 82
    • 0037093533 scopus 로고    scopus 로고
    • Modulation of podocyte phenotype in collapsing glomerulopathy
    • Barisoni L, Kopp JB. 2002. Modulation of podocyte phenotype in collapsing glomerulopathy. Microsc. Res. Tech. 57:254-62
    • (2002) Microsc. Res. Tech. , vol.57 , pp. 254-262
    • Barisoni, L.1    Kopp, J.B.2
  • 83
    • 0033764489 scopus 로고    scopus 로고
    • Wilm's tumor suppressor gene WT-1: From structure to renal pathophysiologic features
    • Mrowka C, Schedl A. 2000. Wilm's tumor suppressor gene WT-1: From structure to renal pathophysiologic features. J. Am. Soc. Nephrol. 11:S106-S115
    • (2000) J. Am. Soc. Nephrol. , vol.11
    • Mrowka, C.1    Schedl, A.2
  • 84
    • 4644312002 scopus 로고    scopus 로고
    • The dysregulated glomerular cell growth in Denys-Drash syndrome
    • Yang AH, Chen JY, Chen BF. 2004. The dysregulated glomerular cell growth in Denys-Drash syndrome. Virchows Arch. 445:305-14
    • (2004) Virchows Arch. , vol.445 , pp. 305-314
    • Yang, A.H.1    Chen, J.Y.2    Chen, B.F.3
  • 85
    • 0037377697 scopus 로고    scopus 로고
    • RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy
    • Wendt TM, Tanji N, Quo J, Kislinger TR, Qu W, et al. 2003. RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy. Am. J. Pathol. 162:1123-37
    • (2003) Am. J. Pathol. , vol.162 , pp. 1123-1137
    • Wendt, T.M.1    Tanji, N.2    Quo, J.3    Kislinger, T.R.4    Qu, W.5
  • 88
    • 0030817707 scopus 로고    scopus 로고
    • High glucose stimulates expression of p27 in cultured mouse mesangial cells: Relationship to hypertrophy
    • Wolf G, Schroeder R, Ziyadeh FN, Thaiss F, Zahner G, Stahl RA. 1997. High glucose stimulates expression of p27 in cultured mouse mesangial cells: Relationship to hypertrophy. Am. J. Physiol. 273:348-56
    • (1997) Am. J. Physiol. , vol.273 , pp. 348-356
    • Wolf, G.1    Schroeder, R.2    Ziyadeh, F.N.3    Thaiss, F.4    Zahner, G.5    Stahl, R.A.6
  • 89
    • 0031655355 scopus 로고    scopus 로고
    • Transcriptional activation of TGF-B in mesangial cell culture by high glucose concentration
    • Hoffman BB, Sharma K, Zhu Y, Ziyadeh FN. 1998. Transcriptional activation of TGF-B in mesangial cell culture by high glucose concentration. Kidney Int. 58:1107-16
    • (1998) Kidney Int. , vol.58 , pp. 1107-1116
    • Hoffman, B.B.1    Sharma, K.2    Zhu, Y.3    Ziyadeh, F.N.4
  • 90
    • 0032835393 scopus 로고
    • Role of angiotensin II in glucose mediated inhibition of mesangial matrix degradation
    • Singh R, Alavi N, Singh AK, Leehey DJ. 1994. Role of angiotensin II in glucose mediated inhibition of mesangial matrix degradation. Diabetes 48:2066-73
    • (1994) Diabetes , vol.48 , pp. 2066-2073
    • Singh, R.1    Alavi, N.2    Singh, A.K.3    Leehey, D.J.4
  • 92
    • 0034947508 scopus 로고    scopus 로고
    • Development and prevention of diabetic nephropathy in RAGE overexpressing mice
    • Yamamoto Y, Kato I, Doi T, Yonekura H, Ohashi S, et al. 2001. Development and prevention of diabetic nephropathy in RAGE overexpressing mice. J. Clin. Invest. 108:261-68
    • (2001) J. Clin. Invest. , vol.108 , pp. 261-268
    • Yamamoto, Y.1    Kato, I.2    Doi, T.3    Yonekura, H.4    Ohashi, S.5
  • 94
    • 0031033557 scopus 로고    scopus 로고
    • Alterations in the expression of the alpha 3 beta 1 integrin in certain membrane domains of the glomerular epithelial cells (podocytes) in diabetes mellitus
    • 88b. Regoli M, Bendayan M. 1997. Alterations in the expression of the alpha 3 beta 1 integrin in certain membrane domains of the glomerular epithelial cells (podocytes) in diabetes mellitus. Diabetologia 40:15-22
    • (1997) Diabetologia , vol.40 , pp. 15-22
    • Regoli, M.1    Bendayan, M.2
  • 95
    • 0031900717 scopus 로고    scopus 로고
    • High glucose stimulates MCP-1 in human mesangial cells
    • Ihm C, Park JK, Hong SP, Lee TW, Cho BS, et al. 1998. High glucose stimulates MCP-1 in human mesangial cells. Nephron 79:33-37
    • (1998) Nephron , vol.79 , pp. 33-37
    • Ihm, C.1    Park, J.K.2    Hong, S.P.3    Lee, T.W.4    Cho, B.S.5
  • 96
    • 10744229528 scopus 로고    scopus 로고
    • The pattern recognition receptor (RAGE) is a counter receptor for leukocyte integrins: A novel pathway for inflammatory cell recuritment
    • Chavakis T, Bierhaus A, Al-Fakhri N, Schneider D, Witte S, et al. 2003. The pattern recognition receptor (RAGE) is a counter receptor for leukocyte integrins: a novel pathway for inflammatory cell recuritment. J. Exp. Med. 198:1507-15
    • (2003) J. Exp. Med. , vol.198 , pp. 1507-1515
    • Chavakis, T.1    Bierhaus, A.2    Al-Fakhri, N.3    Schneider, D.4    Witte, S.5
  • 97
    • 20844448302 scopus 로고    scopus 로고
    • Diabetic nephropathy: Linking histology, cell biology, and genetics
    • Adler S. 2004. Diabetic nephropathy: Linking histology, cell biology, and genetics. Kidney Int. 66:2095-2106
    • (2004) Kidney Int. , vol.66 , pp. 2095-2106
    • Adler, S.1
  • 98
    • 0025292712 scopus 로고
    • Identification of mutations in the COL4A5 collagen gene in Alport syndrome
    • Barker D, Hostikka S, Zhou J, Chow LT, Oliphassnt AR, et al. 1990. Identification of mutations in the COL4A5 collagen gene in Alport syndrome. Science 248:1224-26
    • (1990) Science , vol.248 , pp. 1224-1226
    • Barker, D.1    Hostikka, S.2    Zhou, J.3    Chow, L.T.4    Oliphassnt, A.R.5
  • 99
    • 0028168648 scopus 로고
    • Identification of mutations in the α3 (IV) and α4(IV) collagen genes in autosomal recessive Alport syndrome
    • Mochizuki T, Lemmink H, Mariyama M, Antignac C, Gubler MC, et al. 1994. Identification of mutations in the α3 (IV) and α4(IV) collagen genes in autosomal recessive Alport syndrome. Nature Genet. 8(1):77-82
    • (1994) Nature Genet. , vol.8 , Issue.1 , pp. 77-82
    • Mochizuki, T.1    Lemmink, H.2    Mariyama, M.3    Antignac, C.4    Gubler, M.C.5
  • 101
    • 0015428067 scopus 로고
    • Alport's syndrome: Emphasizing electron microscopic studies of the glomerulus
    • Spear G, Slusser R. 1972. Alport's syndrome: emphasizing electron microscopic studies of the glomerulus. Am. J. Pathol. 69(2):213-24
    • (1972) Am. J. Pathol. , vol.69 , Issue.2 , pp. 213-224
    • Spear, G.1    Slusser, R.2
  • 102
    • 0023605514 scopus 로고
    • Alport's syndrome: Specificity and pathogenesis of glomerular basement membrane alterations
    • Rumpelt H. 1987. Alport's syndrome: specificity and pathogenesis of glomerular basement membrane alterations. Pediatr. Nephrol. 1(3):422-27
    • (1987) Pediatr. Nephrol. , vol.1 , Issue.3 , pp. 422-427
    • Rumpelt, H.1
  • 105
    • 0028171098 scopus 로고
    • Collagen IV alpha 3, alpha 4, and alpha 5 chains in rodent basal laminae: Sequence, distribution, association with laminins, and developmental switches
    • Miner J, Sanes J. 1994. Collagen IV alpha 3, alpha 4, and alpha 5 chains in rodent basal laminae: sequence, distribution, association with laminins, and developmental switches. J. Cell Biol. 127(3):879-91
    • (1994) J. Cell Biol. , vol.127 , Issue.3 , pp. 879-891
    • Miner, J.1    Sanes, J.2
  • 106
    • 0031754846 scopus 로고    scopus 로고
    • Role of distinct type IV collagen networks in glomerular development and function
    • Harvey S, Zheng K, Sado Y, Naito I, Ninomiya Y, et al. 1998. Role of distinct type IV collagen networks in glomerular development and function. Kidney Int. 54(6):1857-66
    • (1998) Kidney Int. , vol.54 , Issue.6 , pp. 1857-1866
    • Harvey, S.1    Zheng, K.2    Sado, Y.3    Naito, I.4    Ninomiya, Y.5
  • 107
    • 0031000529 scopus 로고    scopus 로고
    • Isoform switching of type IV collagen is developmentally arrested in X-linked Alport syndrome leading to increased susceptibility of renal basement membranes to endoproteolysis
    • Kalluri R, Shield C, Todd P, Hudson BG, Neilson EG. 1997. Isoform switching of type IV collagen is developmentally arrested in X-linked Alport syndrome leading to increased susceptibility of renal basement membranes to endoproteolysis. J. Clin. Invest. 99(10): 2470-78
    • (1997) J. Clin. Invest. , vol.99 , Issue.10 , pp. 2470-2478
    • Kalluri, R.1    Shield, C.2    Todd, P.3    Hudson, B.G.4    Neilson, E.G.5
  • 108
    • 0027974208 scopus 로고
    • Immunohistochemical study of α1-5 chains of type IV collagen in hereditary nephritis
    • Nakanishi K, Yoshikawa N, Iijima K, Kitagawa K, Nakamura H, et al. 1994. Immunohistochemical study of α1-5 chains of type IV collagen in hereditary nephritis. Kidney Int. 46(5):1413-21
    • (1994) Kidney Int. , vol.46 , Issue.5 , pp. 1413-1421
    • Nakanishi, K.1    Yoshikawa, N.2    Iijima, K.3    Kitagawa, K.4    Nakamura, H.5
  • 109
    • 0030457613 scopus 로고    scopus 로고
    • Molecular and functional defects in kidneys of mice lacking collagen α3(IV): Implications for Alport syndrome
    • Miner J, Sanes J. 1996. Molecular and functional defects in kidneys of mice lacking collagen α3(IV): Implications for Alport syndrome. J. Cell. Biol. 135(5):1403-13
    • (1996) J. Cell. Biol. , vol.135 , Issue.5 , pp. 1403-1413
    • Miner, J.1    Sanes, J.2
  • 111
    • 0036174534 scopus 로고    scopus 로고
    • Quantitative trait loci influence renal disease progression in a mouse model of Alport syndrome
    • Andrews K, Mudd J, Li C, Miner JH. 2002. Quantitative trait loci influence renal disease progression in a mouse model of Alport syndrome. Am. J. Pathol. 160(2):721-30
    • (2002) Am. J. Pathol. , vol.160 , Issue.2 , pp. 721-730
    • Andrews, K.1    Mudd, J.2    Li, C.3    Miner, J.H.4
  • 112
    • 0032502667 scopus 로고    scopus 로고
    • Glomerular basement membrane. Identification of a novel disulfide-cross-linked network of α3, α4 and α5 chains of type IV collagen and its implications for the pathogenesis of Alport syndrome
    • Gunwar S, Ballester F, Noelken ME, Sado Y, Ninomiya Y, Hudson BG. 1998. Glomerular basement membrane. Identification of a novel disulfide-cross-linked network of α3, α4 and α5 chains of type IV collagen and its implications for the pathogenesis of Alport syndrome. J. Biol. Chem. 273(15):8767-75
    • (1998) J. Biol. Chem. 273 , Issue.15 , pp. 8767-8775
    • Gunwar, S.1    Ballester, F.2    Noelken, M.E.3    Sado, Y.4    Ninomiya, Y.5    Hudson, B.G.6
  • 113
    • 0037336010 scopus 로고    scopus 로고
    • Laminin-1 reexpression in Alport mouse glomerular basement membranes
    • Abrahamson D, Prettyman A, Robert B, St John PL. 2003. Laminin-1 reexpression in Alport mouse glomerular basement membranes. Kidney Int. 63(3):826-34
    • (2003) Kidney Int. , vol.63 , Issue.3 , pp. 826-834
    • Abrahamson, D.1    Prettyman, A.2    Robert, B.3    St. John, P.L.4
  • 114
    • 0035143372 scopus 로고    scopus 로고
    • Abnormal glomerular basement membrane laminins in murine, canine and human Alport syndrome: Aberrant laminin α2 deposition is species independent
    • Kashtan C, Kim Y, Lees GE, Thorner PS, Virtanen I, Miner JH. 2001. Abnormal glomerular basement membrane laminins in murine, canine and human Alport syndrome: Aberrant laminin α2 deposition is species independent. J. Am. Soc. Nephrol. 12(2):252-60
    • (2001) J. Am. Soc. Nephrol. , vol.12 , Issue.2 , pp. 252-260
    • Kashtan, C.1    Kim, Y.2    Lees, G.E.3    Thorner, P.S.4    Virtanen, I.5    Miner, J.H.6
  • 116
  • 117
    • 0035046418 scopus 로고    scopus 로고
    • Segregation of hematuria in thin basement membrane disease with haplotypes at the loci for Alport syndrome
    • Buzza M, Wilson D, Savige J. 2001. Segregation of hematuria in thin basement membrane disease with haplotypes at the loci for Alport syndrome. Kidney Int. 59(5):1670-76
    • (2001) Kidney Int. , vol.59 , Issue.5 , pp. 1670-1676
    • Buzza, M.1    Wilson, D.2    Savige, J.3
  • 118
    • 0037087710 scopus 로고    scopus 로고
    • Association of the tetraspanin CDl51 with the laminin-binding integrins {alpha}3{beta}1, {alpha}6{beta}1, {alpha}6{beta}4 and {alpha}7{beta}1 in cells in culture and in vivo
    • Sterk LMT, Geuijen CA, van den Berg JG, Claessen N, Weening JJ, Sonnenberg A. 2002. Association of the tetraspanin CDl51 with the laminin-binding integrins {alpha}3{beta}1, {alpha}6{beta}1, {alpha}6{beta}4 and {alpha}7{beta}1 in cells in culture and in vivo. J. Cell. Sci. 115(6):1161-73
    • (2002) J. Cell. Sci. , vol.115 , Issue.6 , pp. 1161-1173
    • Sterk, L.M.T.1    Geuijen, C.A.2    Van Den Berg, J.G.3    Claessen, N.4    Weening, J.J.5    Sonnenberg, A.6
  • 119
    • 4944239350 scopus 로고    scopus 로고
    • CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin
    • Karamatic Crew V, Burton N, Kagan A, Green CA, Levene C, et al. 2004. CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin. Blood 104:2217-23
    • (2004) Blood , vol.104 , pp. 2217-2223
    • Karamatic Crew, V.1    Burton, N.2    Kagan, A.3    Green, C.A.4    Levene, C.5
  • 120
    • 8444221929 scopus 로고    scopus 로고
    • Human laminin {beta}2 deficiency causes congenital nephrosis with mesangial sclerosis and distinct eye abnormalities
    • Zenker M, Aigner T, Wendler O, Tralau T, Muntefering H, et al. 2004. Human laminin {beta}2 deficiency causes congenital nephrosis with mesangial sclerosis and distinct eye abnormalities. Hum. Mol. Genet. 13:2625-32
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 2625-2632
    • Zenker, M.1    Aigner, T.2    Wendler, O.3    Tralau, T.4    Muntefering, H.5
  • 121
    • 0029127384 scopus 로고
    • The renal glomerulus of mice lacking s-laminin/laminin B2: Nephrosis despite molecular compensation by laminin B1
    • Noakes P, Miner J, Gautam M, Cunningham JM, Sanes JR, Merlie JP. 1995. The renal glomerulus of mice lacking s-laminin/laminin B2: nephrosis despite molecular compensation by laminin B1. Nature Genet. 10(4):400-406
    • (1995) Nature Genet. , vol.10 , Issue.4 , pp. 400-406
    • Noakes, P.1    Miner, J.2    Gautam, M.3    Cunningham, J.M.4    Sanes, J.R.5    Merlie, J.P.6
  • 122
    • 0031800728 scopus 로고    scopus 로고
    • Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome
    • Dreyer S, Zhou G, Baldini A, Winterpacht A, Zabel B, et al. 1998. Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome. Nat. Genet. 19(1):47-50
    • (1998) Nat. Genet. , vol.19 , Issue.1 , pp. 47-50
    • Dreyer, S.1    Zhou, G.2    Baldini, A.3    Winterpacht, A.4    Zabel, B.5
  • 123
    • 0035134740 scopus 로고    scopus 로고
    • Regulation of glomerular basement membrane collagen expression by LMX1B contributes to renal disease in nail patella syndrome
    • Morello R, Zhou G, Dreyer SD, Harvey SJ, Ninomiya Y, et al. 2001. Regulation of glomerular basement membrane collagen expression by LMX1B contributes to renal disease in nail patella syndrome. Nature Genet. 27(2):205-208
    • (2001) Nature Genet. , vol.27 , Issue.2 , pp. 205-208
    • Morello, R.1    Zhou, G.2    Dreyer, S.D.3    Harvey, S.J.4    Ninomiya, Y.5
  • 124
    • 0036120564 scopus 로고    scopus 로고
    • Transcriptional induction of slit diaphragm proteins by Lmx1b is required in podocyte differentiation
    • Miner JH, Morello R, Andrews KL, Li C, Antignac C, et al. 2002. Transcriptional induction of slit diaphragm proteins by Lmx1b is required in podocyte differentiation. J. Clin. Invest. 109(8):1065-72
    • (2002) J. Clin. Invest. , vol.109 , Issue.8 , pp. 1065-1072
    • Miner, J.H.1    Morello, R.2    Andrews, K.L.3    Li, C.4    Antignac, C.5


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