The regulation of mesangial cell proliferation

Nephron - Experimental Nephrology

Volumn 108, Issue 4, 2008, Pages

  Cove Smith, Andrea ^a   Hendry, Bruce M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Calcium; Cell cycle; Glomerular; Nephritis; Ras; Renal

Indexed keywords

CALCIUM; CYCLIN D1; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE; PLATELET DERIVED GROWTH FACTOR; RAS PROTEIN; TRANSCRIPTION FACTOR E2F;

ANTIGEN ANTIBODY COMPLEX; CELL CYCLE; CELL FUNCTION; CELL PROLIFERATION; CYTOKINE RELEASE; DIABETIC NEPHROPATHY; EXTRACELLULAR MATRIX; GLOMERULUS FILTRATION; IMMUNE RESPONSE; IMMUNOGLOBULIN A NEPHROPATHY; KIDNEY DISEASE; MACROMOLECULE; MESANGIUM CELL; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; SHORT SURVEY; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; CELL CYCLE PROTEINS; CELL PROLIFERATION; FEEDBACK; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MESANGIAL CELLS; MODELS, BIOLOGICAL;

EID: 43949141768     PISSN: 16602129     EISSN: None     Source Type: Journal    
DOI: 10.1159/000127359     Document Type: Short Survey

References (15)

1. Hendry BM, Khwaja A, et al: Distinct functions for Ras GTPases in the control of proliferation and apoptosis in mouse and human mesangial cells. Kidney Int 2006;69:99-104.
2. Sterzel RB, Schulze-Lohoff E, et al: Interactions between glomerular mesangial cells, cytokines, and extracellular matrix. J Am Soc Nephrol 1992;2(10 suppl):S126-S131.
3. Schlondorff D: The glomerular mesangial cell: an expanding role for a specialized pericyte. Faseb J 1987;1:272-281.
4. Shultz PJ, DiCorleto PE, et al: Mesangial cells express PDGF mRNAs and proliferate in response to PDGF. Am J Physiol 1988;255:F674-F684.
5. Johnson RJ, Raines EW, et al: Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor. J Exp Med 1992;175:1413-1416.
6. Schocklmann HO, Lang S, et al: Regulation of mesangial cell proliferation. Kidney Int 1999;56:1199-1207.
7. Pippin JW, Qu Q, et al: Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin-dependent kinase antagonist. J Clin Invest 1997;100:2512-2520.
8. Marshall CB, Shankland SJ: Cell cycle and glomerular disease: a minireview. Nephron Exp Nephrol 2006;102:e39-e48.
9. Maeshima Y, Kashihara N, et al: Inhibition of mesangial cell proliferation by E2F decoy oligodeoxynucleotide in vitro and in vivo. J Clin Invest 1998;101:2589-2597.
10. Khwaja A, Sharpe CC, et al: The inhibition of human mesangial cell proliferation by Strans, trans-farnesylthiosalicylic acid. Kidney Int 2005;68:474-486.
11. Clarke HC, Kocher HM, et al: Ras antagonist farnesylthiosalicylic acid (FTS) reduces glomerular cellular proliferation and macrophage number in rat thy-1 nephritis. J Am Soc Nephrol 2003;14:848-854.
12. Yoshimura A, Inui K, et al: Simvastatin suppresses glomerular cell proliferation and macrophage infiltration in rats with mesangial proliferative nephritis. J Am Soc Nephrol 1998;9:2027-2039.
13. Rodman DM, Reese K, et al: Low-voltage-activated (T-type) calcium channels control proliferation of human pulmonary artery myocytes. Circ Res 2005;96:864-872.
14. Kahl CR, Means AR: Regulation of cell cycle progression by calcium/calmodulin-dependent pathways. Endocr Rev 2003;24:719-736.
15. Yao J, Davies LA, et al: Molecular basis for the modulation of native T-type Ca2+ channels in vivo by Ca2+/calmodulin-dependent protein kinase II. J Clin Invest 2006;116:2403-2412.