-
1
-
-
27744462451
-
Incidence of end-stage renal disease among persons with diabetes: United States, 1990-2002
-
Incidence of end-stage renal disease among persons with diabetes: United States, 1990-2002. MMWR Morb Mortal Wkly Rep 2005; 54:1097-1100.
-
(2005)
MMWR Morb Mortal Wkly Rep
, vol.54
, pp. 1097-1100
-
-
-
2
-
-
10644259663
-
From hyperglycemia to diabetic kidney disease: The role of metabolic, hemodynamic, intracellular factors and growth factors/cytokines
-
Schrijvers BF, De Vriese AS, Flyvbjerg A. From hyperglycemia to diabetic kidney disease: the role of metabolic, hemodynamic, intracellular factors and growth factors/cytokines. Endocr Rev 2004; 25:971-1010.
-
(2004)
Endocr Rev
, vol.25
, pp. 971-1010
-
-
Schrijvers, B.F.1
De Vriese, A.S.2
Flyvbjerg, A.3
-
3
-
-
0002437244
-
Intercapillary lesions in the glomeruli of the kidney
-
Kimmelstiel P, Wilson C. Intercapillary lesions in the glomeruli of the kidney. Am J Pathol 1936; 12:83-98.
-
(1936)
Am J Pathol
, vol.12
, pp. 83-98
-
-
Kimmelstiel, P.1
Wilson, C.2
-
4
-
-
33745058119
-
The podocyte's response to injury: Role in proteinuria and glomerulosclerosis
-
This is an erudite review of the myriad mechanisms that play a role in podocyte injury in a variety of pathological states including diabetes mellitus
-
Shankland SJ. The podocyte's response to injury: role in proteinuria and glomerulosclerosis. Kidney Int 2006; 69:2131-2147. This is an erudite review of the myriad mechanisms that play a role in podocyte injury in a variety of pathological states including diabetes mellitus.
-
(2006)
Kidney Int
, vol.69
, pp. 2131-2147
-
-
Shankland, S.J.1
-
5
-
-
20044362239
-
From the periphery of the glomerular capillary wall toward the center of disease: Podocyte injury comes of age in diabetic nephropathy
-
Wolf G, Chen S, Ziyadeh FN. From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy. Diabetes 2005; 54:1626-1634.
-
(2005)
Diabetes
, vol.54
, pp. 1626-1634
-
-
Wolf, G.1
Chen, S.2
Ziyadeh, F.N.3
-
6
-
-
0034056744
-
Roles of the podocyte in glomerular function
-
Pavenstadt H. Roles of the podocyte in glomerular function. Am J Physiol Renal Physiol 2000; 278:F173-F179.
-
(2000)
Am J Physiol Renal Physiol
, vol.278
-
-
Pavenstadt, H.1
-
7
-
-
0031029379
-
Podocyte loss and progressive glomerular injury in type II diabetes
-
Pagtalunan ME, Miller PL, Jumping-Eagle S, et al. Podocyte loss and progressive glomerular injury in type II diabetes. J Clin Invest 1997; 99:342-348.
-
(1997)
J Clin Invest
, vol.99
, pp. 342-348
-
-
Pagtalunan, M.E.1
Miller, P.L.2
Jumping-Eagle, S.3
-
8
-
-
0036789206
-
Podocyte number in normotensive type 1 diabetic patients with albuminuria
-
White KE, Bilous RW, Marshall SM, et al. Podocyte number in normotensive type 1 diabetic patients with albuminuria. Diabetes 2002; 51:3083-3089.
-
(2002)
Diabetes
, vol.51
, pp. 3083-3089
-
-
White, K.E.1
Bilous, R.W.2
Marshall, S.M.3
-
9
-
-
34547611903
-
Podocyte detachment and reduced glomerular capillary endothelial fenestration in human type 1 diabetic nephropathy
-
This novel study directly quantitated podocyte detachment and effacement in diabetic nephropathy in humans
-
Toyoda M, Najafian B, Kim Y, et al. Podocyte detachment and reduced glomerular capillary endothelial fenestration in human type 1 diabetic nephropathy. Diabetes 2007; 56:2155-2160. This novel study directly quantitated podocyte detachment and effacement in diabetic nephropathy in humans.
-
(2007)
Diabetes
, vol.56
, pp. 2155-2160
-
-
Toyoda, M.1
Najafian, B.2
Kim, Y.3
-
10
-
-
12444302841
-
Podocytes that detach in experimental membranous nephropathy are viable
-
Petermann AT, Krofft R, Blonski M, et al. Podocytes that detach in experimental membranous nephropathy are viable. Kidney Int 2003; 64:1222-1231.
-
(2003)
Kidney Int
, vol.64
, pp. 1222-1231
-
-
Petermann, A.T.1
Krofft, R.2
Blonski, M.3
-
11
-
-
33644783770
-
-
Susztak K, Raff AC, Schiffer M, Bottinger EP. Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy. Diabetes 2006; 55:225-233. These results, obtained with murine models of type 1 and type 2 diabetes mellitus, suggest that podocyte apoptosis/depletion represents a novel early mechanism in the pathogenesis of diabetic nephropathy. A role for glucose-induced ROS production in the initiation of podocyte apoptosis is also investigated.
-
Susztak K, Raff AC, Schiffer M, Bottinger EP. Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy. Diabetes 2006; 55:225-233. These results, obtained with murine models of type 1 and type 2 diabetes mellitus, suggest that podocyte apoptosis/depletion represents a novel early mechanism in the pathogenesis of diabetic nephropathy. A role for glucose-induced ROS production in the initiation of podocyte apoptosis is also investigated.
-
-
-
-
12
-
-
33645808515
-
-
Siu B, Saha J, Smoyer WE, et al. Reduction in podocyte density as a pathologic feature in early diabetic nephropathy in rodents: prevention by lipoic acid treatment. BMC Nephrol 2006; 7:6. This study described the salutary effect of antioxidant therapy on podocyte number and density in a rodent model of type 1 diabetes mellitus.
-
Siu B, Saha J, Smoyer WE, et al. Reduction in podocyte density as a pathologic feature in early diabetic nephropathy in rodents: prevention by lipoic acid treatment. BMC Nephrol 2006; 7:6. This study described the salutary effect of antioxidant therapy on podocyte number and density in a rodent model of type 1 diabetes mellitus.
-
-
-
-
13
-
-
34248352591
-
-
Yoo TH, Li JJ, Kim JJ, et al. Activation of the renin-angiotensin system within podocytes in diabetes. Kidney Int 2007; 71:1019-1027. These results indicate that increased angiotensinogen levels and a concomitant increase in expression of the AII type 1 receptor in podocytes results in the increased angiotensin II activity profiled in diabetes mellitus.
-
Yoo TH, Li JJ, Kim JJ, et al. Activation of the renin-angiotensin system within podocytes in diabetes. Kidney Int 2007; 71:1019-1027. These results indicate that increased angiotensinogen levels and a concomitant increase in expression of the AII type 1 receptor in podocytes results in the increased angiotensin II activity profiled in diabetes mellitus.
-
-
-
-
14
-
-
33745309083
-
-
Rincon-Choles H, Vasylyeva TL, Pergola PE, et al. ZO-1 expression and phosphorylation in diabetic nephropathy. Diabetes 2006; 55:894-900. The findings presented in this paper suggest that alterations in the content, localization, and phosphorylation status of ZO-1 may be relevant to the pathogenesis of proteinuria in diabetes mellitus
-
Rincon-Choles H, Vasylyeva TL, Pergola PE, et al. ZO-1 expression and phosphorylation in diabetic nephropathy. Diabetes 2006; 55:894-900. The findings presented in this paper suggest that alterations in the content, localization, and phosphorylation status of ZO-1 may be relevant to the pathogenesis of proteinuria in diabetes mellitus.
-
-
-
-
15
-
-
33644533898
-
-
Dai T, Natarajan R, Nast CC, et al. Glucose and diabetes: effects on podocyte and glomerular p38MAPK, heat shock protein 25, and actin cytoskeleton. Kidney Int 2006; 69:806-814. These studies delineated roles for p38MAPK and pHSP25 in the acute adaptation of podocyte structure and function to glycemic stress.
-
Dai T, Natarajan R, Nast CC, et al. Glucose and diabetes: effects on podocyte and glomerular p38MAPK, heat shock protein 25, and actin cytoskeleton. Kidney Int 2006; 69:806-814. These studies delineated roles for p38MAPK and pHSP25 in the acute adaptation of podocyte structure and function to glycemic stress.
-
-
-
-
16
-
-
33749120097
-
High glucose and advanced glycosylated end-products affect the expression of alpha-actinin-4 in glomerular epithelial cells
-
Ha TS. High glucose and advanced glycosylated end-products affect the expression of alpha-actinin-4 in glomerular epithelial cells. Nephrology (Carlton) 2006; 11:435-441.
-
(2006)
Nephrology (Carlton)
, vol.11
, pp. 435-441
-
-
Ha, T.S.1
-
17
-
-
33644995630
-
High ambient glucose levels modulates the production of MMP-9 and alpha5(IV) collagen by cultured podocytes
-
Bai Y, Wang L, Li Y, et al. High ambient glucose levels modulates the production of MMP-9 and alpha5(IV) collagen by cultured podocytes. Cell Physiol Biochem 2006; 17:57-68.
-
(2006)
Cell Physiol Biochem
, vol.17
, pp. 57-68
-
-
Bai, Y.1
Wang, L.2
Li, Y.3
-
18
-
-
32244446658
-
The human glomerular podocyte is a novel target for insulin action
-
Coward RJ, Welsh GI, Yang J, et al. The human glomerular podocyte is a novel target for insulin action. Diabetes 2005; 54:3095-3102.
-
(2005)
Diabetes
, vol.54
, pp. 3095-3102
-
-
Coward, R.J.1
Welsh, G.I.2
Yang, J.3
-
19
-
-
34047099749
-
-
Coward RJ, Welsh GI, Koziell A, et al. Nephrin is critical for the action of insulin on human glomerular podocytes. Diabetes 2007; 56:1127-1135. The studies detailed in this paper establish a novel role for nephrin in vesicular docking and insulin responsiveness of the podocyte
-
Coward RJ, Welsh GI, Koziell A, et al. Nephrin is critical for the action of insulin on human glomerular podocytes. Diabetes 2007; 56:1127-1135. The studies detailed in this paper establish a novel role for nephrin in vesicular docking and insulin responsiveness of the podocyte.
-
-
-
-
20
-
-
0027249280
-
Glomerular hyperfiltration in insulin-dependent diabetes mellitus is correlated with enhanced growth hormone secretion
-
Blankestijn PJ, Derkx FH, Birkenhager JC, et al. Glomerular hyperfiltration in insulin-dependent diabetes mellitus is correlated with enhanced growth hormone secretion. J Clin Endocrinol Metab 1993; 77:498-502.
-
(1993)
J Clin Endocrinol Metab
, vol.77
, pp. 498-502
-
-
Blankestijn, P.J.1
Derkx, F.H.2
Birkenhager, J.C.3
-
21
-
-
0025064856
-
Increased overnight growth hormone concentrations in diabetic compared with normal adolescents
-
Edge JA, Dunger DB, Matthews DR, et al. Increased overnight growth hormone concentrations in diabetic compared with normal adolescents. J Clin Endocrinol Metab 1990; 69:1356-1362.
-
(1990)
J Clin Endocrinol Metab
, vol.69
, pp. 1356-1362
-
-
Edge, J.A.1
Dunger, D.B.2
Matthews, D.R.3
-
22
-
-
0018918978
-
Increased growth hormone response to dopamine infusion in insulin-dependent diabetic subjects
-
Lorenzi M, Karam JH, McIlroy MB, Forsham PH. Increased growth hormone response to dopamine infusion in insulin-dependent diabetic subjects. J Clin Invest 1980; 65:146-153.
-
(1980)
J Clin Invest
, vol.65
, pp. 146-153
-
-
Lorenzi, M.1
Karam, J.H.2
McIlroy, M.B.3
Forsham, P.H.4
-
23
-
-
0022473080
-
Relationships between growth factors (somatomedin C and growth hormone) and body development, metabolic control, and retinal changes in children and adolescents with IDDM
-
Salardi S, Cacciari E, Ballardini D, et al. Relationships between growth factors (somatomedin C and growth hormone) and body development, metabolic control, and retinal changes in children and adolescents with IDDM. Diabetes 1986; 35:832-836.
-
(1986)
Diabetes
, vol.35
, pp. 832-836
-
-
Salardi, S.1
Cacciari, E.2
Ballardini, D.3
-
24
-
-
0025078918
-
Glomerular lesions in mice transgenic for growth hormone and insulin-like growth factor-I. Relationship between increased glomerular size and mesangial sclerosis
-
Doi T, Striker LJ, Gibson CC, et al. Glomerular lesions in mice transgenic for growth hormone and insulin-like growth factor-I. Relationship between increased glomerular size and mesangial sclerosis. Am J Pathol 1990; 137:541-552.
-
(1990)
Am J Pathol
, vol.137
, pp. 541-552
-
-
Doi, T.1
Striker, L.J.2
Gibson, C.C.3
-
25
-
-
0030888138
-
Liver and kidney growth hormone (GH) receptors are regulated differently in diabetic GH and GH antagonist transgenic mice
-
Chen NY, Chen WY, Kopchick JJ. Liver and kidney growth hormone (GH) receptors are regulated differently in diabetic GH and GH antagonist transgenic mice. Endocrinology 1997; 138:1988-1994.
-
(1997)
Endocrinology
, vol.138
, pp. 1988-1994
-
-
Chen, N.Y.1
Chen, W.Y.2
Kopchick, J.J.3
-
26
-
-
0028018441
-
Experimental diabetic renal growth: Role of growth hormone and insulin-like growth factor-I
-
Muchaneta-Kubara EC, Sayed-Ahmed N, Besbas N, et al. Experimental diabetic renal growth: role of growth hormone and insulin-like growth factor-I. Nephrol Dial Transplant 1994; 9:1395-1401.
-
(1994)
Nephrol Dial Transplant
, vol.9
, pp. 1395-1401
-
-
Muchaneta-Kubara, E.C.1
Sayed-Ahmed, N.2
Besbas, N.3
-
27
-
-
0019805712
-
Kidney function and size in normal subjects before and during growth hormone administration for one week
-
Christiansen JS, Gammelgaard J, Orskov H, et al. Kidney function and size in normal subjects before and during growth hormone administration for one week. Eur J Clin Invest 1981; 11:487-490.
-
(1981)
Eur J Clin Invest
, vol.11
, pp. 487-490
-
-
Christiansen, J.S.1
Gammelgaard, J.2
Orskov, H.3
-
28
-
-
0031871668
-
Contribution of growth hormone and IGF-1 to early diabetic nephropathy in type 1 diabetes
-
Cummings EA, Sochett EB, Dekker MG, et al. Contribution of growth hormone and IGF-1 to early diabetic nephropathy in type 1 diabetes. Diabetes 1998; 47:1341-1346.
-
(1998)
Diabetes
, vol.47
, pp. 1341-1346
-
-
Cummings, E.A.1
Sochett, E.B.2
Dekker, M.G.3
-
29
-
-
34249789876
-
Identification of the glomerular podocyte as a target for growth hormone action
-
These studies establish the podocyte as a novel target of growth hormone action
-
Reddy GR, Pushpanathan MJ, Ransom RF, et al. Identification of the glomerular podocyte as a target for growth hormone action. Endocrinology 2007; 148:2045-2055. These studies establish the podocyte as a novel target of growth hormone action.
-
(2007)
Endocrinology
, vol.148
, pp. 2045-2055
-
-
Reddy, G.R.1
Pushpanathan, M.J.2
Ransom, R.F.3
|