Peroxisome proliferator-activated receptor γ (PPARγ) and its target genes are downstream effectors of FoxO1 protein in islet β-cells, mechanism ofβ-cell compensation and failure

Journal of Biological Chemistry

Volumn 288, Issue 35, 2013, Pages 25440-25449

  Gupta, Dhananjay ^a   Leahy, Averi A ^a   Monga, Navjot ^a   Peshavaria, Mina ^a   Jetton, Thomas L ^a   Leahy, Jack L ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR MECHANISM; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; TARGET GENES; TYPE-2 DIABETES;

CELLS; CYTOLOGY; FAILURE (MECHANICAL); GENES; MAMMALS;

CELL SIGNALING;

GASTRIC INHIBITORY POLYPEPTIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PYRUVATE CARBOXYLASE; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR PDX 1;

ANIMAL CELL; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIABETES MELLITUS; GENE EXPRESSION; GENE TARGETING; HUMAN; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

CHROMATIN IMMUNOPRECIPITATION (CHIP); GENE EXPRESSION; IMMUNOFLUORESCENCE; MOUSE MODELS; PANCREATIC ISLETS; PDX1; PYRUVATE CARBOXYLASE; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL LINE; CELL NUCLEUS; DIABETES MELLITUS, EXPERIMENTAL; FORKHEAD TRANSCRIPTION FACTORS; INSULIN-SECRETING CELLS; MALE; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; PPAR GAMMA; RATS; RATS, ZUCKER; TRANSCRIPTION, GENETIC;

EID: 84883356602     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.486852     Document Type: Article

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