In vivo and in vitro studies of a functional peroxisome proliferator-activated receptor γ response element in the mouse pdx-1 promoter

Journal of Biological Chemistry

Volumn 283, Issue 47, 2008, Pages 32462-32470

  Gupta, Dhananjay ^a   Jetton, Thomas L ^a   Mortensen, Richard M ^b   Duan, Sheng Zhong ^b   Peshavaria, Mina ^b   Leahy, Jack L ^a,c  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF VERMONT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; CELL CULTURE; CYTOLOGY; ELECTROPHORETIC MOBILITY; GLUCOSE; LAWS AND LEGISLATION; NUCLEIC ACIDS; RNA;

CELL DIFFERENTIATIONS; CELL LINES; CELL PHYSIOLOGIES; CHROMATIN IMMUNOPRECIPITATION ANALYSIS; CYTOARCHITECTURE; ELECTROPHORETIC MOBILITY SUPERSHIFT ASSAYS; IN VITRO; IN VITRO STUDIES; IN-VIVO; INSULIN SECRETIONS; NUCLEAR EXTRACTS; PEROXISOME PROLIFERATOR- ACTIVATED RECEPTORS; PROMOTER ACTIVITIES; PROTEIN LEVELS; RESPONSE ELEMENTS; RETINOID; RNA INTERFERENCES; SPECIFIC BINDINGS; THIAZOLIDINEDIONE; TRANSIENT TRANSFECTION ASSAYS; TYPE 2 DIABETES;

PHYSIOLOGY;

2,4 THIAZOLIDINEDIONE DERIVATIVE; CELL EXTRACT; CRE RECOMBINASE; GLUCOSE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RETINOID X RECEPTOR; TRANSCRIPTION FACTOR PDX 1; TROGLITAZONE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL NUCLEUS; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOARCHITECTURE; DNA RESPONSIVE ELEMENT; DRUG EFFECT; GEL MOBILITY SHIFT ASSAY; GLUCOSE INTOLERANCE; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IN VITRO GENE TRANSFER; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; LOXP SITE; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR BINDING; RNA INTERFERENCE; SEQUENCE HOMOLOGY; TRANSCRIPTION REGULATION;

ANIMALS; BASE SEQUENCE; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; HUMANS; HYPERGLYCEMIA; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MALE; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PPAR GAMMA; PROMOTER REGIONS, GENETIC; RESPONSE ELEMENTS; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANS-ACTIVATORS;

MUS;

EID: 57749098781     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M801813200     Document Type: Article

References (44)

1. Francis, G. A., Fayard, E., Picard, F., and Auwerx, J. (2003) Annu. Rev. Physiol. 65, 261-311
2. Rosen, E. D., and Spiegelman, B. M. (2001) J. Biol. Chem. 276, 37731-37734
3. Picard, F., and Auwerx, J. (2002) Annu. Rev. Nutr. 22, 167-197
4. Lehrke, M., and Lazar, M. A. (2005) Cell 123, 992-999
5. Kliewer, S. A., Umesono, K., Noonan, D. J., Heyman, R. A., and Evans, R. M. (1992) Nature 358, 771-774
6. Gearing, K. L., Gottlicher, M., Teboul, M., Widmark, E., and Gustafsson, J. A. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 1440-1444
7. Ijpenberg, A., Jeannin, E., Wahli, W., and Desvergne, B. (1997) J. Biol. Chem. 272, 20108-20117
8. Hsu, M. H., Palmer, C. N., Song, W., Griffin, K. J., and Johnson, E. F. (1998) J. Biol. Chem. 273, 27988-27997
9. Yki-Jarvinen, H. (2004) N. Engl. J. Med. 351, 1106-1118
10. Ohtani, K. I., Shimizu, H., Sato, N., and Mori, M. (1998) Endocrinology 139, 172-178
11. Rosen, E. D., Kulkarni, R. N., Sarraf, P., Ozcan, U., Okada, T., Hsu, G. H., Eisenman, D., Magnuson, M. A., Gonzalez, F. J., Kahn, C. R., and Spiegelman, B. M. (2003) Mol. Cell. Biol. 23, 7222-7229
12. Lin, C. Y., Gurlo, T., Haataja, L. O., Hsueh, W. A., and Butler, P. C. (2005) J. Clin. Endocrinol. Metab. 90, 6678-6686
13. Buchanan, T. A., Xiang, A. H., Peters, R. K., Kjos, S. L., Marroquin, A., Goico, J., Ochoa, C., Tan, S., Berkowitz, K., Hodis, H. N., and Azen, S. P. (2002) Diabetes 51, 2796-2803
14. Knowler, W. C., Hamman, R. F., Edelstein, S. L., Barrett-Connor, E., Ehrmann, D. A., Walker, E. A., Fowler, S. E., Nathan, D. M., Kahn, S. E., and Diabetes Prevention Program Research Group (2005) Diabetes 54, 1150-1156
15. Xiang, A. H., Peters, R. K., Kjos, S. L., Marroquin, A., Goico, J., Ochoa, C., Kawakubo, M., and Buchanan, T. A. (2006) Diabetes 55, 517-522
16. DREAM (Diabetes REduction Assessment with Ramipril and Rosiglitazone Medication) Trial Investigators, Gerstein, H. C., Yusuf, S., Bosch, J., Pogue, J., Sheridan, P., Dinccag, N., Hanefeld, M., Hoogwerf, B., Laakso, M., Mohan, V., Shaw, J., Zinman, B., and Holman, R. R. (2006) Lancet 368, 1096-1105
17. Kahn, S. E., Haffner, S. M., Heise, M. A., Herman, W. H., Holman, R. R., Jones, N. P., Kravitz, B. G., Lachin, J. M., O'Neill, M. C., Zinman, B., Viberti, G., and ADOPT Study Group (2006) N. Engl. J. Med. 355, 2427-2443
18. Feige, J. N., Gelman, L., Michalik, L., Desvergne, B., and Wahli, W. (2006) Prog. Lipid Res. 45, 120-159
19. Liu, Y. Q., Montanya, E., and Leahy, J. L. (2001) Diabetologia 44, 1026-1033
20. Jetton, T. L., Liu, Y. Q., Trotman, W. E., Nevin, P. W., Sun, X.-J., and Leahy, J. L. (2001) Diabetologia 44, 2056-2065
21. Liu, Y. Q., Nevin, P. W., and Leahy, J. L. (2000) Am. J. Physiol. 279, E68-E73
22. Moibi, J. A., Gupta, D., Jetton, T. L., Peshavaria, M., Desai, R., and Leahy, J. L. (2007) Diabetes 56, 88-95
23. Ahlgren, U., Jonsson, J., Jonsson, L., Simu, K., and Edlund, H. (1998) Genes Dev. 12, 1763-1768
24. Holland, A. M., Hale, M. A., Kagami, H., Hammer, R. E., and MacDonald, R. J. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 12236-12241
25. Brissova, M., Shiota, M., Nicholson, W. E., Gannon, M., Knobel, S. M., Piston, D. W., Wright, C. V., and Powers, A. C. (2002) J. Biol. Chem. 277, 11225-11232
26. Johnson, J. D., Ahmed, N. T., Luciani, D. S., Han, Z., Tran, H., Fujita, J., Misler, S., Edlund, H., and Polonsky, K. S. (2003) J. Clin. Investig. 111, 1147-1160
27. Servitja, J. M., and Ferrer, J. (2004) Diabetologia 47, 597-613
28. Wang, H., Iezzi, M., Theander, S., Antinozzi, P. A., Gauthier, B. R., Halban, P. A., and Wollheim, C. B. (2005) Diabetologia 48, 720-731
29. Ivashchenko, C. Y., Duan, S. Z., Usher, M. G., and Mortensen, R. M. (2007) Am. J. Physiol. 293, G319-G326
30. Gu, G., Dubauskaite, J., and Melton, D. A. (2002) Development (Camb.) 129, 2447-2457
31. Jetton, T. L., Lausier, J., LaRock, K., Trotman, W. E., Larmie, B., Habibovic, A., Peshavaria, M., and Leahy, J. L. (2005) Diabetes 54, 2294-2304
32. Gannon, M., Herrera, P.-L., and Wright, C. V. E. (2000) Genesis 26, 143-144
33. Lemay, D. G., and Hwang, D. H. (2006) J. Lipid Res. 47, 1583-1587
34. Temple, K. A., Cohen, R. N., Wondisford, S. R., Yu, C., Deplewski, D., and Wondisford, F. E. (2005) J. Biol. Chem. 280, 3529-3540
35. Gerrish, K., Gannon, M., Shih, D., Henderson, E., Stoffel, M., Wright, C. V., and Stein, R. (2000) J. Biol. Chem. 275, 3485-3492
36. Tugwood, J. D., Issemann, I., Anderson, R. G., Bundell, K. R., McPheat, W. L., and Green, S. (1992) EMBO J. 11, 433-439
37. Schisler, J. C., Jensen, P. B., Taylor, D. G., Becker, T. C., Knop, F. K., Takekawa, S., German, M., Weir, G. C., Lu, D., Mirmira, R. G., and Newgard, C. B. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 7297-7302
38. Kulkarni, R. N., Jhala, U. S., Winnay, J. N., Krajewski, S., Montminy, M., and Kahn, C. R. (2004) J. Clin. Investig. 114, 828-836
39. Brissova, M., Blaha, M., Spear, C., Nicholson, W., Radhika, A., Shiota, M., Charron, M. J., Wright, C. V., and Powers, A. C. (2005) Am. J. Physiol. 288, E707-E714
40. Lee, J.-Y., Ristow, M., Lin, X., White, M. F., Magnuson, M. A., and Hennighausen, L. (2006) J. Biol. Chem. 281, 2649-2653
41. Lee, J.-Y., and Hennighausen, L. (2005) Biochem. Biophys. Res. Commun. 334, 764-768
42. Niswender, K. D., and Magnuson, M. A. (2007) J. Clin. Investig. 117, 2753-2756
43. Braissant, O., Foufelle, F., Scotto, C., Dauca, M., and Wahli, W. (1996) Endocrinology 137, 354-366
44. Dubois, M., Pattou, F., Kerr-Conte, J., Gmyr, V., Vandewalle, B., Desreumaux, P., Auwerx, J., Schoonjans, K., and Lefebvre, J. (2000) Diabetologia 43, 1165-1169