메뉴 건너뛰기




Volumn 153, Issue 10, 2012, Pages 4593-4599

Rosiglitazone promotes PPARγ-dependent and -independent alterations in gene expression in mouse islets

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; CD36 ANTIGEN; CRE RECOMBINASE; GLUCAGON; GLUCOSE TRANSPORTER 2; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; ROSIGLITAZONE; SURVIVIN; TRANSCRIPTION FACTOR NKX6.1; TRANSCRIPTION FACTOR PDX 1;

EID: 84866769484     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2012-1243     Document Type: Article
Times cited : (15)

References (36)
  • 1
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ(PPAR γ)
    • Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA 1995 An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ(PPAR γ). J Biol Chem 270:12953-12956
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 2
    • 59149084957 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ agonists as insulin sensitizers: From the discovery to recent progress
    • Cho N, Momose Y 2008 Peroxisome proliferator-activated receptor γ agonists as insulin sensitizers: from the discovery to recent progress. Curr Top Med Chem 8:1483-1507
    • (2008) Curr Top Med Chem , vol.8 , pp. 1483-1507
    • Cho, N.1    Momose, Y.2
  • 3
    • 0030297919 scopus 로고    scopus 로고
    • Adipogenesis and obesity: Rounding out the big picture
    • Spiegelman BM, Flier JS 1996 Adipogenesis and obesity: rounding out the big picture. Cell 87:377-389
    • (1996) Cell , vol.87 , pp. 377-389
    • Spiegelman, B.M.1    Flier, J.S.2
  • 5
    • 57749098781 scopus 로고    scopus 로고
    • In vivo and in vitro studies of a functional peroxisome proliferator-activated receptor γ response element in the mouse pdx-1 promoter
    • Gupta D, Jetton TL, Mortensen RM, Duan SZ, Peshavaria M, Leahy JL 2008 In vivo and in vitro studies of a functional peroxisome proliferator-activated receptor γ response element in the mouse pdx-1 promoter. J Biol Chem 283:32462-32470
    • (2008) J Biol Chem , vol.283 , pp. 32462-32470
    • Gupta, D.1    Jetton, T.L.2    Mortensen, R.M.3    Duan, S.Z.4    Peshavaria, M.5    Leahy, J.L.6
  • 6
    • 0031847401 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ agonist, rosiglitazone, protects against nephropathy and pancreatic islet abnormalities in Zucker fatty rats
    • Buckingham RE, Al-Barazanji KA, Toseland CD, Slaughter M, Connor SC, West A, Bond B, Turner NC, Clapham JC 1998 Peroxisome proliferator-activated receptor-γ agonist, rosiglitazone, protects against nephropathy and pancreatic islet abnormalities in Zucker fatty rats. Diabetes 47:1326-1334
    • (1998) Diabetes , vol.47 , pp. 1326-1334
    • Buckingham, R.E.1    Al-Barazanji, K.A.2    Toseland, C.D.3    Slaughter, M.4    Connor, S.C.5    West, A.6    Bond, B.7    Turner, N.C.8    Clapham, J.C.9
  • 8
    • 0034520463 scopus 로고    scopus 로고
    • Rosiglitazone prevents the onset of hyperglycaemia and proteinuria in the Zucker diabetic fatty rat
    • Smith SA, Lister CA, Toseland CD, Buckingham RE 2000 Rosiglitazone prevents the onset of hyperglycaemia and proteinuria in the Zucker diabetic fatty rat. Diabetes Obes Metab 2:363-372
    • (2000) Diabetes Obes Metab , vol.2 , pp. 363-372
    • Smith, S.A.1    Lister, C.A.2    Toseland, C.D.3    Buckingham, R.E.4
  • 11
    • 33947149143 scopus 로고    scopus 로고
    • β-Cell preservation with thiazolidinediones
    • Campbell IW, Mariz S 2007 β-Cell preservation with thiazolidinediones. Diabetes Res Clin Pract 76:163-176
    • (2007) Diabetes Res Clin Pract , vol.76 , pp. 163-176
    • Campbell, I.W.1    Mariz, S.2
  • 13
    • 33847065108 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ regulates expression of PDX-1 and NKX6.1 in INS-1 cells
    • Moibi JA, Gupta D, Jetton TL, Peshavaria M, Desai R, Leahy JL 2007 Peroxisome proliferator-activated receptor-γ regulates expression of PDX-1 and NKX6.1 in INS-1 cells. Diabetes 56:88-95
    • (2007) Diabetes , vol.56 , pp. 88-95
    • Moibi, J.A.1    Gupta, D.2    Jetton, T.L.3    Peshavaria, M.4    Desai, R.5    Leahy, J.L.6
  • 14
    • 77953177935 scopus 로고    scopus 로고
    • Physiologic and pharmacologic modulation of GIP receptor expression in β-cells by PPARγ signaling: Possible mechanism for the GIP resistance in type 2 diabetes
    • Gupta D, Peshavaria M, Monga N, Jetton TL, Leahy JL 2010 Physiologic and pharmacologic modulation of GIP receptor expression in β-cells by PPARγ signaling: possible mechanism for the GIP resistance in type 2 diabetes. Diabetes 59:1445-1450
    • (2010) Diabetes , vol.59 , pp. 1445-1450
    • Gupta, D.1    Peshavaria, M.2    Monga, N.3    Jetton, T.L.4    Leahy, J.L.5
  • 15
    • 0033864402 scopus 로고    scopus 로고
    • Identification and functional characterization of the peroxisomal proliferator response element in rat GLUT2 promoter
    • Kim HI, Kim JW, Kim SH, Cha JY, Kim KS, Ahn YH 2000 Identification and functional characterization of the peroxisomal proliferator response element in rat GLUT2 promoter. Diabetes 49:1517-1524
    • (2000) Diabetes , vol.49 , pp. 1517-1524
    • Kim, H.I.1    Kim, J.W.2    Kim, S.H.3    Cha, J.Y.4    Kim, K.S.5    Ahn, Y.H.6
  • 16
    • 0036535976 scopus 로고    scopus 로고
    • Troglitazone does not protect rat pancreatic β cells against free fatty acid-induced cytotoxicity
    • Cnop M, Hannaert JC, Pipeleers DG 2002 Troglitazone does not protect rat pancreatic β cells against free fatty acid-induced cytotoxicity. Biochem Pharmacol 63:1281-1285
    • (2002) Biochem Pharmacol , vol.63 , pp. 1281-1285
    • Cnop, M.1    Hannaert, J.C.2    Pipeleers, D.G.3
  • 18
    • 0038772154 scopus 로고    scopus 로고
    • PPAR-γ overexpression suppresses glucose-induced proinsulin biosynthesis and insulin release synergistically with pioglitazone in MIN6 cells
    • Nakamichi Y, Kikuta T, Ito E, Ohara-Imaizumi M, Nishiwaki C, Ishida H, Nagamatsu S 2003 PPAR-γ overexpression suppresses glucose-induced proinsulin biosynthesis and insulin release synergistically with pioglitazone in MIN6 cells. Biochem Biophys Res Commun 306:832-836
    • (2003) Biochem Biophys Res Commun , vol.306 , pp. 832-836
    • Nakamichi, Y.1    Kikuta, T.2    Ito, E.3    Ohara-Imaizumi, M.4    Nishiwaki, C.5    Ishida, H.6    Nagamatsu, S.7
  • 19
    • 23044478417 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor α (PPARα) potentiates, whereas PPARγ attenuates, glucose-stimulated insulin secretion in pancreatic β-cells
    • Ravnskjaer K, Boergesen M, Rubi B, Larsen JK, Nielsen T, Fridriksson J, Maechler P, Mandrup S 2005 Peroxisome proliferator-activated receptor α (PPARα) potentiates, whereas PPARγ attenuates, glucose-stimulated insulin secretion in pancreatic β-cells. Endocrinology 146:3266-3276
    • (2005) Endocrinology , vol.146 , pp. 3266-3276
    • Ravnskjaer, K.1    Boergesen, M.2    Rubi, B.3    Larsen, J.K.4    Nielsen, T.5    Fridriksson, J.6    Maechler, P.7    Mandrup, S.8
  • 20
    • 70349423273 scopus 로고    scopus 로고
    • Inhibition of human insulin gene transcription by peroxisome proliferator-activated receptor γ and thiazolidinedione oral antidiabetic drugs
    • Schinner S, Krätzner R, Baun D, Dickel C, Blume R, Oetjen E 2009 Inhibition of human insulin gene transcription by peroxisome proliferator-activated receptor γ and thiazolidinedione oral antidiabetic drugs. Br J Pharmacol 157:736-745
    • (2009) Br J Pharmacol , vol.157 , pp. 736-745
    • Schinner, S.1    Krätzner, R.2    Baun, D.3    Dickel, C.4    Blume, R.5    Oetjen, E.6
  • 22
    • 23244467098 scopus 로고    scopus 로고
    • Efficient recombination in pancreatic islets by a tamoxifen-inducible Cre-recombinase
    • Zhang H, Fujitani Y, Wright CV, Gannon M 2005 Efficient recombination in pancreatic islets by a tamoxifen-inducible Cre-recombinase. Genesis 42:210-217
    • (2005) Genesis , vol.42 , pp. 210-217
    • Zhang, H.1    Fujitani, Y.2    Wright, C.V.3    Gannon, M.4
  • 23
    • 0036578921 scopus 로고    scopus 로고
    • β-Cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter β-cell mass
    • Kulkarni RN, Holzenberger M, Shih DQ, Ozcan U, Stoffel M, Magnuson MA, Kahn CR 2002 β-Cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter β-cell mass. Nat Genet 31:111-115
    • (2002) Nat Genet , vol.31 , pp. 111-115
    • Kulkarni, R.N.1    Holzenberger, M.2    Shih, D.Q.3    Ozcan, U.4    Stoffel, M.5    Magnuson, M.A.6    Kahn, C.R.7
  • 25
    • 51349103007 scopus 로고    scopus 로고
    • MafA is a dedicated activator of the insulin gene in vivo
    • Artner I, Hang Y, Guo M, Gu G, Stein R 2008 MafA is a dedicated activator of the insulin gene in vivo. J Endocrinol 198:271-279
    • (2008) J Endocrinol , vol.198 , pp. 271-279
    • Artner, I.1    Hang, Y.2    Guo, M.3    Gu, G.4    Stein, R.5
  • 30
    • 9444296497 scopus 로고    scopus 로고
    • Liver X receptor activation stimulates insulin secretion via modulation of glucose and lipid metabolism in pancreatic β-cells
    • Efanov AM, Sewing S, Bokvist K, Gromada J 2004 Liver X receptor activation stimulates insulin secretion via modulation of glucose and lipid metabolism in pancreatic β-cells. Diabetes 53(Suppl 3):S75-S78
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 3
    • Efanov, A.M.1    Sewing, S.2    Bokvist, K.3    Gromada, J.4
  • 33
    • 25844454854 scopus 로고    scopus 로고
    • Increased fatty acid desaturation and enhanced expression of stearoyl coenzyme A desaturase protects pancreatic beta-cells from lipoapoptosis
    • Busch AK, Gurisik E, Cordery DV, Sudlow M, Denyer GS, Laybutt DR, Hughes WE, Biden TJ 2005 Increased fatty acid desaturation and enhanced expression of stearoyl coenzyme A desaturase protects pancreatic beta-cells from lipoapoptosis. Diabetes 54:2917-2924
    • (2005) Diabetes , vol.54 , pp. 2917-2924
    • Busch, A.K.1    Gurisik, E.2    Cordery, D.V.3    Sudlow, M.4    Denyer, G.S.5    Laybutt, D.R.6    Hughes, W.E.7    Biden, T.J.8
  • 34
    • 3042781392 scopus 로고    scopus 로고
    • Hormone-sensitive lipase has a role in lipid signaling for insulin secretion but is nonessential for the incretin action of glucagon-like peptide 1
    • Peyot ML, Nolan CJ, Soni K, Joly E, Lussier R, Corkey BE, Wang SP, Mitchell GA, Prentki M 2004 Hormone-sensitive lipase has a role in lipid signaling for insulin secretion but is nonessential for the incretin action of glucagon-like peptide 1. Diabetes 53:1733-1742
    • (2004) Diabetes , vol.53 , pp. 1733-1742
    • Peyot, M.L.1    Nolan, C.J.2    Soni, K.3    Joly, E.4    Lussier, R.5    Corkey, B.E.6    Wang, S.P.7    Mitchell, G.A.8    Prentki, M.9
  • 36
    • 7044260753 scopus 로고    scopus 로고
    • Pioglitazone reduces islet triglyceride content and restores impaired glucose-stimulated insulin secretion in heterozygous peroxisome proliferator-activated receptor-γ-deficient mice on a high-fat diet
    • Matsui J, Terauchi Y, Kubota N, Takamoto I, Eto K, Yamashita T, Komeda K, Yamauchi T, Kamon J, Kita S, Noda M, Kadowaki T 2004 Pioglitazone reduces islet triglyceride content and restores impaired glucose-stimulated insulin secretion in heterozygous peroxisome proliferator-activated receptor-γ-deficient mice on a high-fat diet. Diabetes 53:2844-2854
    • (2004) Diabetes , vol.53 , pp. 2844-2854
    • Matsui, J.1    Terauchi, Y.2    Kubota, N.3    Takamoto, I.4    Eto, K.5    Yamashita, T.6    Komeda, K.7    Yamauchi, T.8    Kamon, J.9    Kita, S.10    Noda, M.11    Kadowaki, T.12


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.