Targeted elimination of peroxisome proliferator-activated receptor γ in β cells leads to abnormalities in islet mass without compromising glucose homeostasis

Molecular and Cellular Biology

Volumn 23, Issue 20, 2003, Pages 7222-7229

  Rosen, Evan D ^a   Kulkarni, Rohit N ^b   Sarraf, Pasha ^c,d   Ozcan, Umut ^b   Okada, Terumasa ^b   Hsu, Chung Hsin ^a   Eisenman, Daniel ^c,d   Magnuson, Mark A ^e   Gonzalez, Frank J ^f   Kahn, C Ronald ^b   Spiegelman, Bruce M ^c,d  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b JOSLIN DIABETES CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d DANA FARBER CANCER INSTITUTE   (United States)

^e VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; GLUCOSE; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; ROSIGLITAZONE; THIAZOLIDINE DERIVATIVE; TROGLITAZONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; GLUCOSE HOMEOSTASIS; INSULIN RELEASE; INSULIN RESISTANCE; INSULINOMA; KNOCKOUT MOUSE; LIPID DIET; MOUSE; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL HYPERPLASIA; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT;

ANIMALS; BLOOD GLUCOSE; CELL DIFFERENTIATION; CELL DIVISION; CELL SEPARATION; CHROMANS; CROSSES, GENETIC; DOSE-RESPONSE RELATIONSHIP, DRUG; EXONS; FLOW CYTOMETRY; GLUCOSE; GLUCOSE TOLERANCE TEST; HYPOGLYCEMIC AGENTS; IMMUNOHISTOCHEMISTRY; INSULIN; ISLETS OF LANGERHANS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; RECEPTORS, CYTOPLASMIC AND NUCLEAR; THIAZOLIDINEDIONES; TIME FACTORS; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 0141450254     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.20.7222-7229.2003     Document Type: Article

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