PPAR-γ activation restores pancreatic islet SERCA2 levels and prevents β-cell dysfunction under conditions of hyperglycemic and cytokine stress

Molecular Endocrinology

Volumn 26, Issue 2, 2012, Pages 257-271

  Kono, Tatsuyoshi ^a   Ahn, Geonyoung ^a   Moss, Dan R ^a   Gann, Liann ^a   Zarain Herzberg, Angel ^b   Nishiki, Yurika ^a   Fueger, Patrick T ^a   Ogihara, Takeshi ^c   Evans Molina, Carmella ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Biochemistry School of Medicine   (Mexico)

^c JUNTENDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 5; GLUCOSE; INTERLEUKIN 1BETA; ISOPROTEIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; ROSCOVITINE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SERINE;

ARTICLE; BINDING KINETICS; CALCIUM HOMEOSTASIS; CELL STRESS; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IMMUNOFLUORESCENCE; INHIBITION KINETICS; PANCREAS INSUFFICIENCY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSACTIVATION; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION;

MUS; RATTUS;

EID: 84856262896     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2011-1181     Document Type: Article

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