-
2
-
-
0037328613
-
NF-kappaB activation in cancer: A challenge for ubiquitination- and proteasome-based therapeutic approach
-
Amit S, Ben-Neriah Y (2003) NF-kappaB activation in cancer: a challenge for ubiquitination- and proteasome-based therapeutic approach. Semin Cancer Biol 13: 15-28
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 15-28
-
-
Amit, S.1
Ben-Neriah, Y.2
-
3
-
-
33645714061
-
The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation
-
Angers S, Thorpe CJ, Biechele TL, Goldenberg SJ, Zheng N, MacCoss MJ, Moon RT (2006) The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation. Nat Cell Biol 8: 348-357
-
(2006)
Nat Cell Biol
, vol.8
, pp. 348-357
-
-
Angers, S.1
Thorpe, C.J.2
Biechele, T.L.3
Goldenberg, S.J.4
Zheng, N.5
Maccoss, M.J.6
Moon, R.T.7
-
4
-
-
79960239873
-
Progressive myoclonic epilepsy-associated gene KCTD7 is a regulator of potassium conductance in neurons
-
Azizieh R, Orduz D, Van Bogaert P, Bouschet T, Rodriguez W, Schiffmann SN, Pirson I, Abramowicz MJ (2011) Progressive myoclonic epilepsy-associated gene KCTD7 is a regulator of potassium conductance in neurons. Mol Neurobiol 44: 111-121
-
(2011)
Mol Neurobiol
, vol.44
, pp. 111-121
-
-
Azizieh, R.1
Orduz, D.2
Van Bogaert, P.3
Bouschet, T.4
Rodriguez, W.5
Schiffmann, S.N.6
Pirson, I.7
Abramowicz, M.J.8
-
5
-
-
84876497280
-
Ubiquitylation-dependent localization of PLK1 in mitosis
-
Beck J, Maerki S, Posch M, Metzger T, Persaud A, Scheel H, Hofmann K, Rotin D, Pedrioli P, Swedlow JR, Peter M, Sumara I (2013) Ubiquitylation- dependent localization of PLK1 in mitosis. Nat Cell Biol 15: 430-439
-
(2013)
Nat Cell Biol
, vol.15
, pp. 430-439
-
-
Beck, J.1
Maerki, S.2
Posch, M.3
Metzger, T.4
Persaud, A.5
Scheel, H.6
Hofmann, K.7
Rotin, D.8
Pedrioli, P.9
Swedlow, J.R.10
Peter, M.11
Sumara, I.12
-
6
-
-
78649974984
-
Dynamics of cullin- RING ubiquitin ligase network revealed by systematic quantitative proteomics
-
Bennett EJ, Rush J, Gygi SP, Harper JW (2010) Dynamics of cullin- RING ubiquitin ligase network revealed by systematic quantitative proteomics. Cell 143: 951-965
-
(2010)
Cell
, vol.143
, pp. 951-965
-
-
Bennett, E.J.1
Rush, J.2
Gygi, S.P.3
Harper, J.W.4
-
7
-
-
0033763056
-
The gene encoding gigaxonin, a new member of the cytoskeletal BTB/kelch repeat family, is mutated in giant axonal neuropathy
-
Bomont P, Cavalier L, Blondeau F, Ben Hamida C, Belal S, Tazir M, Demir E, Topaloglu H, Korinthenberg R, Tuysuz B, Landrieu P, Hentati F, Koenig M (2000) The gene encoding gigaxonin, a new member of the cytoskeletal BTB/kelch repeat family, is mutated in giant axonal neuropathy. Nat Genet 26: 370-374
-
(2000)
Nat Genet
, vol.26
, pp. 370-374
-
-
Bomont, P.1
Cavalier, L.2
Blondeau, F.3
Ben Hamida, C.4
Belal, S.5
Tazir, M.6
Demir, E.7
Topaloglu, H.8
Korinthenberg, R.9
Tuysuz, B.10
Landrieu, P.11
Hentati, F.12
Koenig, M.13
-
8
-
-
84856431125
-
Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities
-
Boyden LM, Choi M, Choate KA, Nelson-Williams CJ, Farhi A, Toka HR, Tikhonova IR, Bjornson R, Mane SM, Colussi G, Lebel M, Gordon RD, Semmekrot BA, Poujol A, Valimaki MJ, De Ferrari ME, Sanjad SA, Gutkin M, Karet FE, Tucci JR et al (2012) Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. Nature 482: 98-102
-
(2012)
Nature
, vol.482
, pp. 98-102
-
-
Boyden, L.M.1
Choi, M.2
Choate, K.A.3
Nelson-Williams, C.J.4
Farhi, A.5
Toka, H.R.6
Tikhonova, I.R.7
Bjornson, R.8
Mane, S.M.9
Colussi, G.10
Lebel, M.11
Gordon, R.D.12
Semmekrot, B.A.13
Poujol, A.14
Valimaki, M.J.15
De Ferrari, M.E.16
Sanjad, S.A.17
Gutkin, M.18
Karet, F.E.19
Tucci, J.R.20
more..
-
9
-
-
43749117536
-
Coordinated activation of the nuclear ubiquitin ligase Cul3-SPOP by the generation of phosphatidylinositol 5-phosphate
-
Bunce MW, Boronenkov IV, Anderson RA (2008) Coordinated activation of the nuclear ubiquitin ligase Cul3-SPOP by the generation of phosphatidylinositol 5-phosphate. J Biol Chem 283: 8678-8686
-
(2008)
J Biol Chem
, vol.283
, pp. 8678-8686
-
-
Bunce, M.W.1
Boronenkov, I.V.2
Anderson, R.A.3
-
10
-
-
84875152063
-
Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases
-
Canning P, Cooper CD, Krojer T, Murray JW, Pike AC, Chaikuad A, Keates T, Thangaratnarajah C, Hojzan V, Marsden BD, Gileadi O, Knapp S, von Delft F, Bullock AN (2013) Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases. J Biol Chem 288: 7803-7814
-
(2013)
J Biol Chem
, vol.288
, pp. 7803-7814
-
-
Canning, P.1
Cooper, C.D.2
Krojer, T.3
Murray, J.W.4
Pike, A.C.5
Chaikuad, A.6
Keates, T.7
Thangaratnarajah, C.8
Hojzan, V.9
Marsden, B.D.10
Gileadi, O.11
Knapp, S.12
Von Delft, F.13
Bullock, A.N.14
-
11
-
-
0030938488
-
The Arabidopsis NPR1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats
-
Cao H, Glazebrook J, Clarke JD, Volko S, Dong X (1997) The Arabidopsis NPR1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats. Cell 88: 57-63
-
(1997)
Cell
, vol.88
, pp. 57-63
-
-
Cao, H.1
Glazebrook, J.2
Clarke, J.D.3
Volko, S.4
Dong, X.5
-
12
-
-
0037329952
-
The eto1, eto2, and eto3 mutations and cytokinin treatment increase ethylene biosynthesis in Arabidopsis by increasing the stability of ACS protein
-
Chae HS, Faure F, Kieber JJ (2003) The eto1, eto2, and eto3 mutations and cytokinin treatment increase ethylene biosynthesis in Arabidopsis by increasing the stability of ACS protein. Plant Cell 15: 545-559
-
(2003)
Plant Cell
, vol.15
, pp. 545-559
-
-
Chae, H.S.1
Faure, F.2
Kieber, J.J.3
-
13
-
-
69249245332
-
Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
-
Chen MH, Wilson CW, Li YJ, Law KK, Lu CS, Gacayan R, Zhang X, Hui CC, Chuang PT (2009a) Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved. Genes Dev 23: 1910-1928
-
(2009)
Genes Dev
, vol.23
, pp. 1910-1928
-
-
Chen, M.H.1
Wilson, C.W.2
Li, Y.J.3
Law, K.K.4
Lu, C.S.5
Gacayan, R.6
Zhang, X.7
Hui, C.C.8
Chuang, P.T.9
-
14
-
-
70349168448
-
Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement
-
Chen Y, Yang Z, Meng M, Zhao Y, Dong N, Yan H, Liu L, Ding M, Peng HB, Shao F (2009b) Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement. Mol Cell 35: 841-855
-
(2009)
Mol Cell
, vol.35
, pp. 841-855
-
-
Chen, Y.1
Yang, Z.2
Meng, M.3
Zhao, Y.4
Dong, N.5
Yan, H.6
Liu, L.7
Ding, M.8
Peng, H.B.9
Shao, F.10
-
15
-
-
84880964732
-
Arabidopsis BPM proteins function as substrate adaptors to a CULLIN3-based E3 ligase to affect fatty acid metabolism in plants
-
(advance online publication, 21 June 2013)
-
Chen L, Lee JH, Weber H, Tohge T, Witt S, Roje S, Fernie AR, Hellmann H (2013) Arabidopsis BPM proteins function as substrate adaptors to a CULLIN3-based E3 ligase to affect fatty acid metabolism in plants. Plant Cell (advance online publication, 21 June 2013)
-
(2013)
Plant Cell
-
-
Chen, L.1
Lee, J.H.2
Weber, H.3
Tohge, T.4
Witt, S.5
Roje, S.6
Fernie, A.R.7
Hellmann, H.8
-
16
-
-
58349085565
-
The BTB ubiquitin ligases ETO1, EOL1 and EOL2 act collectively to regulate ethylene biosynthesis in Arabidopsis by controlling type-2 ACC synthase levels
-
Christians MJ, Gingerich DJ, Hansen M, Binder BM, Kieber JJ, Vierstra RD (2009) The BTB ubiquitin ligases ETO1, EOL1 and EOL2 act collectively to regulate ethylene biosynthesis in Arabidopsis by controlling type-2 ACC synthase levels. Plant J 57: 332-345
-
(2009)
Plant J
, vol.57
, pp. 332-345
-
-
Christians, M.J.1
Gingerich, D.J.2
Hansen, M.3
Binder, B.M.4
Kieber, J.J.5
Vierstra, R.D.6
-
17
-
-
84865834797
-
The light-response BTB1 and BTB2 proteins assemble nuclear ubiquitin ligases that modify phytochrome B and D signaling in Arabidopsis
-
Christians MJ, Gingerich DJ, Hua Z, Lauer TD, Vierstra RD (2012) The light-response BTB1 and BTB2 proteins assemble nuclear ubiquitin ligases that modify phytochrome B and D signaling in Arabidopsis. Plant Physiol 160: 118-134
-
(2012)
Plant Physiol
, vol.160
, pp. 118-134
-
-
Christians, M.J.1
Gingerich, D.J.2
Hua, Z.3
Lauer, T.D.4
Vierstra, R.D.5
-
18
-
-
0034065822
-
Ubiquitin-mediated proteolysis: Biological regulation via destruction
-
Ciechanover A, Orian A, Schwartz AL (2000) Ubiquitin-mediated proteolysis: biological regulation via destruction. Bioessays 22: 442-451
-
(2000)
Bioessays
, vol.22
, pp. 442-451
-
-
Ciechanover, A.1
Orian, A.2
Schwartz, A.L.3
-
19
-
-
77954359968
-
Kelch-like homologue 9 mutation is associated with an early onset autosomal dominant distal myopathy
-
Cirak S, von Deimling F, Sachdev S, Errington WJ, Herrmann R, Bonnemann C, Brockmann K, Hinderlich S, Lindner TH, Steinbrecher A, Hoffmann K, Prive GG, Hannink M, Nurnberg P, Voit T (2010) Kelch-like homologue 9 mutation is associated with an early onset autosomal dominant distal myopathy. Brain 133(Pt 7): 2123-2135
-
(2010)
Brain
, vol.133
, Issue.PART 7
, pp. 2123-2135
-
-
Cirak, S.1
Von Deimling, F.2
Sachdev, S.3
Errington, W.J.4
Herrmann, R.5
Bonnemann, C.6
Brockmann, K.7
Hinderlich, S.8
Lindner, T.H.9
Steinbrecher, A.10
Hoffmann, K.11
Prive, G.G.12
Hannink, M.13
Nurnberg, P.14
Voit, T.15
-
20
-
-
77957825438
-
Pcif1 modulates Pdx1 protein stability and pancreatic beta cell function and survival in mice
-
Claiborn KC, Sachdeva MM, Cannon CE, Groff DN, Singer JD, Stoffers DA (2010) Pcif1 modulates Pdx1 protein stability and pancreatic beta cell function and survival in mice. J Clin Invest 120: 3713-3721
-
(2010)
J Clin Invest
, vol.120
, pp. 3713-3721
-
-
Claiborn, K.C.1
Sachdeva, M.M.2
Cannon, C.E.3
Groff, D.N.4
Singer, J.D.5
Stoffers, D.A.6
-
21
-
-
79952438310
-
Molecular organization of the cullin E3 ligase adaptor KCTD11
-
Correale S, Pirone L, Di Marcotullio L, De Smaele E, Greco A, Mazza D, Moretti M, Alterio V, Vitagliano L, Di Gaetano S, Gulino A, Pedone EM (2011) Molecular organization of the cullin E3 ligase adaptor KCTD11. Biochimie 93: 715-724
-
(2011)
Biochimie
, vol.93
, pp. 715-724
-
-
Correale, S.1
Pirone, L.2
Di Marcotullio, L.3
De Smaele, E.4
Greco, A.5
Mazza, D.6
Moretti, M.7
Alterio, V.8
Vitagliano, L.9
Di Gaetano, S.10
Gulino, A.11
Pedone, E.M.12
-
22
-
-
4544294365
-
The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: Oxidative stress sensing by a Cul3-Keap1 ligase
-
Cullinan SB, Gordan JD, Jin J, Harper JW, Diehl JA (2004) The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase. Mol Cell Biol 24: 8477-8486
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8477-8486
-
-
Cullinan, S.B.1
Gordan, J.D.2
Jin, J.3
Harper, J.W.4
Diehl, J.A.5
-
23
-
-
66449104636
-
The Cul3/Klhdc5 E3 ligase regulates p60/katanin and is required for normal mitosis in mammalian cells
-
Cummings CM, Bentley CA, Perdue SA, Baas PW, Singer JD (2009) The Cul3/Klhdc5 E3 ligase regulates p60/katanin and is required for normal mitosis in mammalian cells. J Biol Chem 284: 11663-11675
-
(2009)
J Biol Chem
, vol.284
, pp. 11663-11675
-
-
Cummings, C.M.1
Bentley, C.A.2
Perdue, S.A.3
Baas, P.W.4
Singer, J.D.5
-
24
-
-
20844433523
-
Molecular and functional characterization of Arabidopsis Cullin 3A
-
Dieterle M, Thomann A, Renou JP, Parmentier Y, Cognat V, Lemonnier G, Muller R, Shen WH, Kretsch T, Genschik P (2005) Molecular and functional characterization of Arabidopsis Cullin 3A. Plant J 41: 386-399
-
(2005)
Plant J
, vol.41
, pp. 386-399
-
-
Dieterle, M.1
Thomann, A.2
Renou, J.P.3
Parmentier, Y.4
Cognat, V.5
Lemonnier, G.6
Muller, R.7
Shen, W.H.8
Kretsch, T.9
Genschik, P.10
-
25
-
-
0036327344
-
Microtubule-associated protein 1B: A neuronal binding partner for gigaxonin
-
Ding J, Liu JJ, Kowal AS, Nardine T, Bhattacharya P, Lee A, Yang Y (2002) Microtubule-associated protein 1B: a neuronal binding partner for gigaxonin. J Cell Biol 158: 427-433
-
(2002)
J Cell Biol
, vol.158
, pp. 427-433
-
-
Ding, J.1
Liu, J.J.2
Kowal, A.S.3
Nardine, T.4
Bhattacharya, P.5
Lee, A.6
Yang, Y.7
-
26
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
-
Dinkova-Kostova AT, Holtzclaw WD, Cole RN, Itoh K,Wakabayashi N, Katoh Y, Yamamoto M, Talalay P (2002) Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants. Proc Natl Acad Sci USA 99: 11908-11913
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
Itoh Kwakabayashi, N.4
Katoh, Y.5
Yamamoto, M.6
Talalay, P.7
-
27
-
-
50449108516
-
Structural insights into NEDD8 activation of cullin-RING ligases: Conformational control of conjugation
-
Duda DM, Borg LA, Scott DC, Hunt HW, Hammel M, Schulman BA (2008) Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation. Cell 134: 995-1006
-
(2008)
Cell
, vol.134
, pp. 995-1006
-
-
Duda, D.M.1
Borg, L.A.2
Scott, D.C.3
Hunt, H.W.4
Hammel, M.5
Schulman, B.A.6
-
28
-
-
84863505152
-
Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase
-
Errington WJ, Khan MQ, Bueler SA, Rubinstein JL, Chakrabartty A, Prive GG (2012) Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase. Structure 20: 1141-1153
-
(2012)
Structure
, vol.20
, pp. 1141-1153
-
-
Errington, W.J.1
Khan, M.Q.2
Bueler, S.A.3
Rubinstein, J.L.4
Chakrabartty, A.5
Prive, G.G.6
-
29
-
-
84855510640
-
Cullin 3 mediates SRC-3 ubiquitination and degradation to control the retinoic acid response
-
Ferry C, Gaouar S, Fischer B, Boeglin M, Paul N, Samarut E, Piskunov A, Pankotai-Bodo G, Brino L, Rochette-Egly C (2011) Cullin 3 mediates SRC-3 ubiquitination and degradation to control the retinoic acid response. Proc Natl Acad Sci USA 108: 20603-20608
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 20603-20608
-
-
Ferry, C.1
Gaouar, S.2
Fischer, B.3
Boeglin, M.4
Paul, N.5
Samarut, E.6
Piskunov, A.7
Pankotai-Bodo, G.8
Brino, L.9
Rochette-Egly, C.10
-
30
-
-
23944491295
-
Arabidopsis has two redundant Cullin3 proteins that are essential for embryo development and that interact with RBX1 and BTB proteins to form multisubunit E3 ubiquitin ligase complexes in vivo
-
Figueroa P, Gusmaroli G, Serino G, Habashi J, Ma L, Shen Y, Feng S, Bostick M, Callis J, Hellmann H, Deng XW (2005) Arabidopsis has two redundant Cullin3 proteins that are essential for embryo development and that interact with RBX1 and BTB proteins to form multisubunit E3 ubiquitin ligase complexes in vivo. Plant Cell 17: 1180-1195
-
(2005)
Plant Cell
, vol.17
, pp. 1180-1195
-
-
Figueroa, P.1
Gusmaroli, G.2
Serino, G.3
Habashi, J.4
Ma, L.5
Shen, Y.6
Feng, S.7
Bostick, M.8
Callis, J.9
Hellmann, H.10
Deng, X.W.11
-
31
-
-
84862298224
-
NPR3 and NPR4 are receptors for the immune signal salicylic acid in plants
-
Fu ZQ, Yan S, Saleh A,WangW, Ruble J, Oka N, Mohan R, Spoel SH, Tada Y, Zheng N, Dong X (2012) NPR3 and NPR4 are receptors for the immune signal salicylic acid in plants. Nature 486: 228-232
-
(2012)
Nature
, vol.486
, pp. 228-232
-
-
Fu, Z.Q.1
Yan, S.2
Awangw, S.3
Ruble, J.4
Oka, N.5
Mohan, R.6
Spoel, S.H.7
Tada, Y.8
Zheng, N.9
Dong, X.10
-
32
-
-
0242575197
-
Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases
-
Furukawa M, He YJ, Borchers C, Xiong Y (2003) Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases. Nat Cell Biol 5: 1001-1007
-
(2003)
Nat Cell Biol
, vol.5
, pp. 1001-1007
-
-
Furukawa, M.1
He, Y.J.2
Borchers, C.3
Xiong, Y.4
-
33
-
-
79955560733
-
Polar-localized NPH3-like proteins regulate polarity and endocytosis of PIN-FORMED auxin efflux carriers
-
Furutani M, Sakamoto N, Yoshida S, Kajiwara T, Robert HS, Friml J, Tasaka M (2011) Polar-localized NPH3-like proteins regulate polarity and endocytosis of PIN-FORMED auxin efflux carriers. Development 138: 2069-2078
-
(2011)
Development
, vol.138
, pp. 2069-2078
-
-
Furutani, M.1
Sakamoto, N.2
Yoshida, S.3
Kajiwara, T.4
Robert, H.S.5
Friml, J.6
Tasaka, M.7
-
34
-
-
0037143725
-
The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis
-
Gagne JM, Downes BP, Shiu SH, Durski AM, Vierstra RD (2002) The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis. Proc Natl Acad Sci USA 99: 11519-11524
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11519-11524
-
-
Gagne, J.M.1
Downes, B.P.2
Shiu, S.H.3
Durski, A.M.4
Vierstra, R.D.5
-
35
-
-
0141750416
-
BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases
-
Geyer R, Wee S, Anderson S, Yates J, Wolf DA (2003) BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases. Mol Cell 12: 783-790
-
(2003)
Mol Cell
, vol.12
, pp. 783-790
-
-
Geyer, R.1
Wee, S.2
Anderson, S.3
Yates, J.4
Wolf, D.A.5
-
37
-
-
21444450086
-
Cullins 3a and 3b assemble with members of the broad complex/tramtrack/ bric - A-brac (BTB) protein family to form essential ubiquitin-protein ligases (E3s) in Arabidopsis
-
Gingerich DJ, Gagne JM, Salter DW, Hellmann H, Estelle M, Ma L, Vierstra RD (2005) Cullins 3a and 3b assemble with members of the broad complex/tramtrack/bric-a-brac (BTB) protein family to form essential ubiquitin-protein ligases (E3s) in Arabidopsis. J Biol Chem 280: 18810-18821
-
(2005)
J Biol Chem
, vol.280
, pp. 18810-18821
-
-
Gingerich, D.J.1
Gagne, J.M.2
Salter, D.W.3
Hellmann, H.4
Estelle, M.5
Ma, L.6
Vierstra, R.D.7
-
38
-
-
35348861423
-
Large-scale, lineage-specific expansion of a bric - A-brac/tramtrack/ broad complex ubiquitin-ligase gene family in rice
-
Gingerich DJ, Hanada K, Shiu SH, Vierstra RD (2007) Large-scale, lineage-specific expansion of a bric-a-brac/tramtrack/broad complex ubiquitin-ligase gene family in rice. Plant Cell 19: 2329-2348
-
(2007)
Plant Cell
, vol.19
, pp. 2329-2348
-
-
Gingerich, D.J.1
Hanada, K.2
Shiu, S.H.3
Vierstra, R.D.4
-
39
-
-
84871679702
-
TRAF2 Sets a threshold for extrinsic apoptosis by tagging caspase-8 with a ubiquitin shutoff timer
-
Gonzalvez F, Lawrence D, Yang B, Yee S, Pitti R, Marsters S, Pham VC, Stephan JP, Lill J, Ashkenazi A (2012) TRAF2 Sets a threshold for extrinsic apoptosis by tagging caspase-8 with a ubiquitin shutoff timer. Mol Cell 48: 888-899
-
(2012)
Mol Cell
, vol.48
, pp. 888-899
-
-
Gonzalvez, F.1
Lawrence, D.2
Yang, B.3
Yee, S.4
Pitti, R.5
Marsters, S.6
Pham, V.C.7
Stephan, J.P.8
Lill, J.9
Ashkenazi, A.10
-
40
-
-
84872176059
-
A quantitative proteomic analysis uncovers the relevance of CUL3 in bladder cancer aggressiveness
-
Grau L, Luque-Garcia JL, Gonzalez-Peramato P, Theodorescu D, Palou J, Fernandez-Gomez JM, Sanchez-Carbayo M (2013) A quantitative proteomic analysis uncovers the relevance of CUL3 in bladder cancer aggressiveness. PLoS One 8: e53328
-
(2013)
PLoS One
, vol.8
-
-
Grau, L.1
Luque-Garcia, J.L.2
Gonzalez-Peramato, P.3
Theodorescu, D.4
Palou, J.5
Fernandez-Gomez, J.M.6
Sanchez-Carbayo, M.7
-
41
-
-
33751252276
-
Cancer metastasis: Building a framework
-
Gupta GP, Massague J (2006) Cancer metastasis: building a framework. Cell 127: 679-695
-
(2006)
Cell
, vol.127
, pp. 679-695
-
-
Gupta, G.P.1
Massague, J.2
-
42
-
-
21144446865
-
Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase
-
Hernandez-Munoz I, Lund AH, van der Stoop P, Boutsma E, Muijrers I, Verhoeven E, Nusinow DA, Panning B, Marahrens Y, van Lohuizen M (2005) Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase. Proc Natl Acad Sci USA 102: 7635-7640
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 7635-7640
-
-
Hernandez-Munoz, I.1
Lund, A.H.2
Van Der Stoop, P.3
Boutsma, E.4
Muijrers, I.5
Verhoeven, E.6
Nusinow, D.A.7
Panning, B.8
Marahrens, Y.9
Van Lohuizen, M.10
-
43
-
-
0037124365
-
Homeodomain protein ATHB6 is a target of the protein phosphatase ABI1 and regulates hormone responses in Arabidopsis
-
Himmelbach A, Hoffmann T, Leube M, Hohener B, Grill E (2002) Homeodomain protein ATHB6 is a target of the protein phosphatase ABI1 and regulates hormone responses in Arabidopsis. EMBO J 21: 3029-3038
-
(2002)
EMBO J
, vol.21
, pp. 3029-3038
-
-
Himmelbach, A.1
Hoffmann, T.2
Leube, M.3
Hohener, B.4
Grill, E.5
-
44
-
-
79955642715
-
The cullin-RING ubiquitin-protein ligases
-
Hua Z, Vierstra RD (2011) The cullin-RING ubiquitin-protein ligases. Annu Rev Plant Biol 62: 299-334
-
(2011)
Annu Rev Plant Biol
, vol.62
, pp. 299-334
-
-
Hua, Z.1
Vierstra, R.D.2
-
45
-
-
84856377924
-
Cullin-3 regulates late endosome maturation
-
Huotari J, Meyer-Schaller N, Hubner M, Stauffer S, Katheder N, Horvath P, Mancini R, Helenius A, Peter M (2012) Cullin-3 regulates late endosome maturation. Proc Natl Acad Sci USA 109: 823-828
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 823-828
-
-
Huotari, J.1
Meyer-Schaller, N.2
Hubner, M.3
Stauffer, S.4
Katheder, N.5
Horvath, P.6
Mancini, R.7
Helenius, A.8
Peter, M.9
-
46
-
-
84655176306
-
The role of ubiquitylation in immune defence and pathogen evasion
-
Jiang X, Chen ZJ (2011) The role of ubiquitylation in immune defence and pathogen evasion. Nat Rev Immunol 12: 35-48
-
(2011)
Nat Rev Immunol
, vol.12
, pp. 35-48
-
-
Jiang, X.1
Chen, Z.J.2
-
47
-
-
7544234937
-
Systematic analysis and nomenclature of mammalian F-box proteins
-
Jin J, Cardozo T, Lovering RC, Elledge SJ, Pagano M, Harper JW (2004) Systematic analysis and nomenclature of mammalian F-box proteins. Genes Dev 18: 2573-2580
-
(2004)
Genes Dev
, vol.18
, pp. 2573-2580
-
-
Jin, J.1
Cardozo, T.2
Lovering, R.C.3
Elledge, S.J.4
Pagano, M.5
Harper, J.W.6
-
48
-
-
84857377700
-
Ubiquitin-dependent regulation of COPII coat size and function
-
Jin L, Pahuja KB, Wickliffe KE, Gorur A, Baumgartel C, Schekman R, Rape M (2012) Ubiquitin-dependent regulation of COPII coat size and function. Nature 482: 495-500
-
(2012)
Nature
, vol.482
, pp. 495-500
-
-
Jin, L.1
Pahuja, K.B.2
Wickliffe, K.E.3
Gorur, A.4
Baumgartel, C.5
Schekman, R.6
Rape, M.7
-
49
-
-
65549085701
-
Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling
-
Jin Z, Li Y, Pitti R, Lawrence D, Pham VC, Lill JR, Ashkenazi A (2009) Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling. Cell 137: 721-735
-
(2009)
Cell
, vol.137
, pp. 721-735
-
-
Jin, Z.1
Li, Y.2
Pitti, R.3
Lawrence, D.4
Pham, V.C.5
Lill, J.R.6
Ashkenazi, A.7
-
50
-
-
84873047315
-
Germline-specific MATH-BTB substrate adaptor MAB1 regulates spindle length and nuclei identity in maize
-
Juranic M, Srilunchang KO, Krohn NG, Leljak-Levanic D, Sprunck S, Dresselhaus T (2012) Germline-specific MATH-BTB substrate adaptor MAB1 regulates spindle length and nuclei identity in maize. Plant Cell 24: 4974-4991
-
(2012)
Plant Cell
, vol.24
, pp. 4974-4991
-
-
Juranic, M.1
Srilunchang, K.O.2
Krohn, N.G.3
Leljak-Levanic, D.4
Sprunck, S.5
Dresselhaus, T.6
-
51
-
-
80052981806
-
Ubiquitin ligase activity of Cul3- KLHL7 protein is attenuated by autosomal dominant retinitis pigmentosa causative mutation
-
Kigoshi Y, Tsuruta F, Chiba T (2011) Ubiquitin ligase activity of Cul3- KLHL7 protein is attenuated by autosomal dominant retinitis pigmentosa causative mutation. J Biol Chem 286: 33613-33621
-
(2011)
J Biol Chem
, vol.286
, pp. 33613-33621
-
-
Kigoshi, Y.1
Tsuruta, F.2
Chiba, T.3
-
52
-
-
77955653742
-
Suppression of NF-kappaB signaling by KEAP1 regulation of IKKbeta activity through autophagic degradation and inhibition of phosphorylation
-
Kim JE, You DJ, Lee C, Ahn C, Seong JY, Hwang JI (2010) Suppression of NF-kappaB signaling by KEAP1 regulation of IKKbeta activity through autophagic degradation and inhibition of phosphorylation. Cell Signal 22: 1645-1654
-
(2010)
Cell Signal
, vol.22
, pp. 1645-1654
-
-
Kim, J.E.1
You, D.J.2
Lee, C.3
Ahn, C.4
Seong, J.Y.5
Hwang, J.I.6
-
53
-
-
16644373473
-
Role of VHL gene mutation in human cancer
-
Kim WY, Kaelin WG (2004) Role of VHL gene mutation in human cancer. J Clin Oncol 22: 4991-5004
-
(2004)
J Clin Oncol
, vol.22
, pp. 4991-5004
-
-
Kim, W.Y.1
Kaelin, W.G.2
-
54
-
-
3543008924
-
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
-
Kobayashi A, Kang MI, Okawa H, Ohtsuji M, Zenke Y, Chiba T, Igarashi K, Yamamoto M (2004) Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2. Mol Cell Biol 24: 7130-7139
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7130-7139
-
-
Kobayashi, A.1
Kang, M.I.2
Okawa, H.3
Ohtsuji, M.4
Zenke, Y.5
Chiba, T.6
Igarashi, K.7
Yamamoto, M.8
-
55
-
-
78049420135
-
The cyclin e regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells
-
Kossatz U, Breuhahn K, Wolf B, Hardtke-Wolenski M, Wilkens L, Steinemann D, Singer S, Brass F, Kubicka S, Schlegelberger B, Schirmacher P, Manns MP, Singer JD, Malek NP (2010) The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells. J Clin Invest 120: 3820-3833
-
(2010)
J Clin Invest
, vol.120
, pp. 3820-3833
-
-
Kossatz, U.1
Breuhahn, K.2
Wolf, B.3
Hardtke-Wolenski, M.4
Wilkens, L.5
Steinemann, D.6
Singer, S.7
Brass, F.8
Kubicka, S.9
Schlegelberger, B.10
Schirmacher, P.11
Manns, M.P.12
Singer, J.D.13
Malek, N.P.14
-
56
-
-
0037083528
-
Cytoskeletal regulation by the Nedd8 ubiquitin-like protein modification pathway
-
Kurz T, Pintard L, Willis JH, Hamill DR, Gonczy P, Peter M, Bowerman B (2002) Cytoskeletal regulation by the Nedd8 ubiquitin-like protein modification pathway. Science 295: 1294-1298
-
(2002)
Science
, vol.295
, pp. 1294-1298
-
-
Kurz, T.1
Pintard, L.2
Willis, J.H.3
Hamill, D.R.4
Gonczy, P.5
Peter, M.6
Bowerman, B.7
-
57
-
-
33646886500
-
BTB domaincontaining speckle-type POZ protein (SPOP) serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase
-
Kwon JE, La M, Oh KH, Oh YM, Kim GR, Seol JH, Baek SH, Chiba T, Tanaka K, Bang OS, Joe CO, Chung CH (2006) BTB domaincontaining speckle-type POZ protein (SPOP) serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase. J Biol Chem 281: 12664-12672
-
(2006)
J Biol Chem
, vol.281
, pp. 12664-12672
-
-
Kwon, J.E.1
La Oh, M.K.H.2
Oh, Y.M.3
Kim, G.R.4
Seol, J.H.5
Baek, S.H.6
Chiba, T.7
Tanaka, K.8
Bang, O.S.9
Joe, C.O.10
Chung, C.H.11
-
58
-
-
83455173677
-
MATH/BTB CRL3 receptors target the homeodomain-leucine zipper ATHB6 to modulate abscisic acid signaling
-
Lechner E, Leonhardt N, Eisler H, Parmentier Y, Alioua M, Jacquet H, Leung J, Genschik P (2011) MATH/BTB CRL3 receptors target the homeodomain-leucine zipper ATHB6 to modulate abscisic acid signaling. Dev Cell 21: 1116-1128
-
(2011)
Dev Cell
, vol.21
, pp. 1116-1128
-
-
Lechner, E.1
Leonhardt, N.2
Eisler, H.3
Parmentier, Y.4
Alioua, M.5
Jacquet, H.6
Leung, J.7
Genschik, P.8
-
59
-
-
70349970493
-
KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta
-
Lee DF, Kuo HP, Liu M, Chou CK, Xia W, Du Y, Shen J, Chen CT, Huo L, Hsu MC, Li CW, Ding Q, Liao TL, Lai CC, Lin AC, Chang YH, Tsai SF, Li LY, Hung MC (2009) KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta. Mol Cell 36: 131-140
-
(2009)
Mol Cell
, vol.36
, pp. 131-140
-
-
Lee, D.F.1
Kuo, H.P.2
Liu, M.3
Chou, C.K.4
Xia, W.5
Du, Y.6
Shen, J.7
Chen, C.T.8
Huo, L.9
Hsu, M.C.10
Li, C.W.11
Ding, Q.12
Liao, T.L.13
Lai, C.C.14
Lin, A.C.15
Chang, Y.H.16
Tsai, S.F.17
Li, L.Y.18
Hung, M.C.19
-
60
-
-
77952580741
-
The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses
-
Lee YR, Yuan WC, Ho HC, Chen CH, Shih HM, Chen RH (2010) The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses. EMBO J 29: 1748-1761
-
(2010)
EMBO J
, vol.29
, pp. 1748-1761
-
-
Lee, Y.R.1
Yuan, W.C.2
Ho, H.C.3
Chen, C.H.4
Shih, H.M.5
Chen, R.H.6
-
61
-
-
80054908957
-
Tumorsuppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1
-
Li C, Ao J, Fu J, Lee DF, Xu J, Lonard D, O'Malley BW(2011) Tumorsuppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1. Oncogene 30: 4350-4364
-
(2011)
Oncogene
, vol.30
, pp. 4350-4364
-
-
Li, C.1
Ao, J.2
Fu, J.3
Lee, D.F.4
Xu, J.5
Lonard, D.6
O'malley, B.W.7
-
62
-
-
0036929129
-
NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1- SKP1 binding and SCF ligases
-
Liu J, Furukawa M, Matsumoto T, Xiong Y (2002) NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1- SKP1 binding and SCF ligases. Mol Cell 10: 1511-1518
-
(2002)
Mol Cell
, vol.10
, pp. 1511-1518
-
-
Liu, J.1
Furukawa, M.2
Matsumoto, T.3
Xiong, Y.4
-
63
-
-
60349085402
-
Analysis of Drosophila segmentation network identifies a JNK pathway factor overexpressed in kidney cancer
-
Liu J, Ghanim M, Xue L, Brown CD, Iossifov I, Angeletti C, Hua S, Negre N, Ludwig M, Stricker T, Al-Ahmadie HA, Tretiakova M, Camp RL, Perera-Alberto M, Rimm DL, Xu T, Rzhetsky A, White KP (2009) Analysis of Drosophila segmentation network identifies a JNK pathway factor overexpressed in kidney cancer. Science 323: 1218-1222
-
(2009)
Science
, vol.323
, pp. 1218-1222
-
-
Liu, J.1
Ghanim, M.2
Xue, L.3
Brown, C.D.4
Iossifov, I.5
Angeletti, C.6
Hua, S.7
Negre, N.8
Ludwig, M.9
Stricker, T.10
Al-Ahmadie, H.A.11
Tretiakova, M.12
Camp, R.L.13
Perera-Alberto, M.14
Rimm, D.L.15
Xu, T.16
Rzhetsky, A.17
White, K.P.18
-
64
-
-
32044444643
-
CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1
-
Lo SC, Hannink M (2006) CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1. Mol Cell Biol 26: 1235-1244
-
(2006)
Mol Cell Biol
, vol.26
, pp. 1235-1244
-
-
Lo, S.C.1
Hannink, M.2
-
65
-
-
33747606306
-
Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling
-
Lo SC, Li X, Henzl MT, Beamer LJ, Hannink M (2006) Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling. EMBO J 25: 3605-3617
-
(2006)
EMBO J
, vol.25
, pp. 3605-3617
-
-
Lo, S.C.1
Li, X.2
Henzl, M.T.3
Beamer, L.J.4
Hannink, M.5
-
66
-
-
84859425383
-
KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron
-
S451-453
-
Louis-Dit-Picard H, Barc J, Trujillano D, Miserey-Lenkei S, Bouatia-Naji N, Pylypenko O, Beaurain G, Bonnefond A, Sand O, Simian C, Vidal-Petiot E, Soukaseum C, Mandet C, Broux F, Chabre O, Delahousse M, Esnault V, Fiquet B, Houillier P, Bagnis CI et al (2012) KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron. Nat Genet 44: 456-460, S451-453
-
(2012)
Nat Genet
, vol.44
, pp. 456-460
-
-
Louis-Dit-Picard, H.1
Barc, J.2
Trujillano, D.3
Miserey-Lenkei, S.4
Bouatia-Naji, N.5
Pylypenko, O.6
Beaurain, G.7
Bonnefond, A.8
Sand, O.9
Simian, C.10
Vidal-Petiot, E.11
Soukaseum, C.12
Mandet, C.13
Broux, F.14
Chabre, O.15
Delahousse, M.16
Esnault, V.17
Fiquet, B.18
Houillier, P.19
Bagnis, C.I.20
more..
-
67
-
-
74049138620
-
The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis
-
Maerki S, Olma MH, Staubli T, Steigemann P, Gerlich DW, Quadroni M, Sumara I, PeterM(2009) The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis. J Cell Biol 187: 791-800
-
(2009)
J Cell Biol
, vol.187
, pp. 791-800
-
-
Maerki, S.1
Olma, M.H.2
Staubli, T.3
Steigemann, P.4
Gerlich, D.W.5
Quadroni, M.6
Sumara, I.7
Peter, M.8
-
68
-
-
78649634794
-
Selective proteolysis sets the tempo of the cell cycle
-
Marrocco K, Bergdoll M, Achard P, Criqui MC, Genschik P (2010) Selective proteolysis sets the tempo of the cell cycle. Curr Opin Plant Biol 13: 631-639
-
(2010)
Curr Opin Plant Biol
, vol.13
, pp. 631-639
-
-
Marrocco, K.1
Bergdoll, M.2
Achard, P.3
Criqui, M.C.4
Genschik, P.5
-
69
-
-
33747728194
-
Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a 'tethering' mechanism: A two-site interaction model for the Nrf2-Keap1 complex
-
McMahon M, Thomas N, Itoh K, Yamamoto M, Hayes JD (2006) Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a 'tethering' mechanism: a two-site interaction model for the Nrf2-Keap1 complex. J Biol Chem 281: 24756-24768
-
(2006)
J Biol Chem
, vol.281
, pp. 24756-24768
-
-
McMahon, M.1
Thomas, N.2
Itoh, K.3
Yamamoto, M.4
Hayes, J.D.5
-
70
-
-
62449196769
-
Large-scale detection of ubiquitination substrates using cell extracts and protein microarrays
-
Merbl Y, Kirschner MW (2009) Large-scale detection of ubiquitination substrates using cell extracts and protein microarrays. Proc Natl Acad Sci USA 106: 2543-2548
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2543-2548
-
-
Merbl, Y.1
Kirschner, M.W.2
-
71
-
-
70349339322
-
Regulation of cullin- RING E3 ubiquitin-ligases by neddylation and dimerization
-
Merlet J, Burger J, Gomes JE, Pintard L (2009) Regulation of cullin- RING E3 ubiquitin-ligases by neddylation and dimerization. Cell Mol Life Sci 66: 1924-1938
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 1924-1938
-
-
Merlet, J.1
Burger, J.2
Gomes, J.E.3
Pintard, L.4
-
72
-
-
0037589924
-
A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression
-
Michel JJ, McCarville JF, Xiong Y (2003) A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression. J Biol Chem 278: 22828-22837
-
(2003)
J Biol Chem
, vol.278
, pp. 22828-22837
-
-
Michel, J.J.1
McCarville, J.F.2
Xiong, Y.3
-
73
-
-
84858127817
-
Emerging regulatory mechanisms in ubiquitin-dependent cell cycle control
-
Mocciaro A, Rape M (2012) Emerging regulatory mechanisms in ubiquitin-dependent cell cycle control. J Cell Sci 125(Pt 2): 255-263
-
(2012)
J Cell Sci
, vol.125
, Issue.PART 2
, pp. 255-263
-
-
Mocciaro, A.1
Rape, M.2
-
74
-
-
0033615489
-
Arabidopsis NPH3: A NPH1 photoreceptor-interacting protein essential for phototropism
-
Motchoulski A, Liscum E (1999) Arabidopsis NPH3: A NPH1 photoreceptor-interacting protein essential for phototropism. Science 286: 961-964
-
(1999)
Science
, vol.286
, pp. 961-964
-
-
Motchoulski, A.1
Liscum, E.2
-
75
-
-
65549169136
-
Control of rapsyn stability by the CUL-3-containing E3 ligase complex
-
Nam S, Min K, Hwang H, Lee HO, Lee JH, Yoon J, Lee H, Park S, Lee J (2009) Control of rapsyn stability by the CUL-3-containing E3 ligase complex. J Biol Chem 284: 8195-8206
-
(2009)
J Biol Chem
, vol.284
, pp. 8195-8206
-
-
Nam, S.1
Min, K.2
Hwang, H.3
Lee, H.O.4
Lee, J.H.5
Yoon, J.6
Lee, H.7
Park, S.8
Lee, J.9
-
76
-
-
84858692205
-
BAZF, a novel component of cullin3-based E3 ligase complex, mediates VEGFR and Notch cross-signaling in angiogenesis
-
Ohnuki H, Inoue H, Takemori N, Nakayama H, Sakaue T, Fukuda S, Miwa D, Nishiwaki E, Hatano M, Tokuhisa T, Endo Y, Nose M, Higashiyama S (2012) BAZF, a novel component of cullin3-based E3 ligase complex, mediates VEGFR and Notch cross-signaling in angiogenesis. Blood 119: 2688-2698
-
(2012)
Blood
, vol.119
, pp. 2688-2698
-
-
Ohnuki, H.1
Inoue, H.2
Takemori, N.3
Nakayama, H.4
Sakaue, T.5
Fukuda, S.6
Miwa, D.7
Nishiwaki, E.8
Hatano, M.9
Tokuhisa, T.10
Endo, Y.11
Nose, M.12
Higashiyama, S.13
-
77
-
-
84875158737
-
The CUL3- KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: Disease- causing mutations in KLHL3 and WNK4 disrupt interaction
-
Ohta A, Schumacher FR, Mehellou Y, Johnson C, Knebel A, Macartney TJ, Wood NT, Alessi DR, Kurz T (2013) The CUL3- KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease- causing mutations in KLHL3 and WNK4 disrupt interaction. Biochem J 451: 111-122
-
(2013)
Biochem J
, vol.451
, pp. 111-122
-
-
Ohta, A.1
Schumacher, F.R.2
Mehellou, Y.3
Johnson, C.4
Knebel, A.5
Macartney, T.J.6
Wood, N.T.7
Alessi, D.R.8
Kurz, T.9
-
78
-
-
40449107193
-
Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth
-
Ohta T, Iijima K, Miyamoto M, Nakahara I, Tanaka H, Ohtsuji M, Suzuki T, Kobayashi A, Yokota J, Sakiyama T, Shibata T, Yamamoto M, Hirohashi S (2008) Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth. Cancer Res 68: 1303-1309
-
(2008)
Cancer Res
, vol.68
, pp. 1303-1309
-
-
Ohta, T.1
Iijima, K.2
Miyamoto, M.3
Nakahara, I.4
Tanaka, H.5
Ohtsuji, M.6
Suzuki, T.7
Kobayashi, A.8
Yokota, J.9
Sakiyama, T.10
Shibata, T.11
Yamamoto, M.12
Hirohashi, S.13
-
79
-
-
33344456501
-
Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer
-
Padmanabhan B, Tong KI, Ohta T, Nakamura Y, Scharlock M, Ohtsuji M, Kang MI, Kobayashi A, Yokoyama S, Yamamoto M (2006) Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer. Mol Cell 21: 689-700
-
(2006)
Mol Cell
, vol.21
, pp. 689-700
-
-
Padmanabhan, B.1
Tong, K.I.2
Ohta, T.3
Nakamura, Y.4
Scharlock, M.5
Ohtsuji, M.6
Kang, M.I.7
Kobayashi, A.8
Yokoyama, S.9
Yamamoto, M.10
-
81
-
-
34547135478
-
Regulation of phototropic signaling in Arabidopsis via phosphorylation state changes in the phototropin 1-interacting protein NPH3
-
Pedmale UV, Liscum E (2007) Regulation of phototropic signaling in Arabidopsis via phosphorylation state changes in the phototropin 1-interacting protein NPH3. J Biol Chem 282: 19992-20001
-
(2007)
J Biol Chem
, vol.282
, pp. 19992-20001
-
-
Pedmale, U.V.1
Liscum, E.2
-
82
-
-
84867084491
-
Cullin-3 regulates vascular smooth muscle function and arterial blood pressure via PPARgamma and RhoA/Rho-kinase
-
Pelham CJ, Ketsawatsomkron P, Groh S, Grobe JL, de Lange WJ, Ibeawuchi SR, Keen HL, Weatherford ET, Faraci FM, Sigmund CD (2012) Cullin-3 regulates vascular smooth muscle function and arterial blood pressure via PPARgamma and RhoA/Rho-kinase. Cell Metab 16: 462-472
-
(2012)
Cell Metab
, vol.16
, pp. 462-472
-
-
Pelham, C.J.1
Ketsawatsomkron, P.2
Groh, S.3
Grobe, J.L.4
De Lange, W.J.5
Ibeawuchi, S.R.6
Keen, H.L.7
Weatherford, E.T.8
Faraci, F.M.9
Sigmund, C.D.10
-
83
-
-
11244351579
-
Function and regulation of cullin-RING ubiquitin ligases
-
Petroski MD, Deshaies RJ (2005) Function and regulation of cullin-RING ubiquitin ligases. Nat Rev Mol Cell Biol 6: 9-20
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 9-20
-
-
Petroski, M.D.1
Deshaies, R.J.2
-
84
-
-
84875724907
-
Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins
-
Pierce NW, Lee JE, Liu X, Sweredoski MJ, Graham RL, Larimore EA, Rome M, Zheng N, Clurman BE, Hess S, Shan SO, Deshaies RJ (2013) Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins. Cell 153: 206-215
-
(2013)
Cell
, vol.153
, pp. 206-215
-
-
Pierce, N.W.1
Lee, J.E.2
Liu, X.3
Sweredoski, M.J.4
Graham, R.L.5
Larimore, E.A.6
Rome, M.7
Zheng, N.8
Clurman, B.E.9
Hess, S.10
Shan, S.O.11
Deshaies, R.J.12
-
85
-
-
0037513423
-
Neddylation and deneddylation of CUL-3 is required to target MEI-1/Katanin for degradation at the meiosis-to-mitosis transition in C. Elegans
-
Pintard L, Kurz T, Glaser S, Willis JH, Peter M, Bowerman B (2003a) Neddylation and deneddylation of CUL-3 is required to target MEI-1/Katanin for degradation at the meiosis-to-mitosis transition in C. elegans. Curr Biol 13: 911-921
-
(2003)
Curr Biol
, vol.13
, pp. 911-921
-
-
Pintard, L.1
Kurz, T.2
Glaser, S.3
Willis, J.H.4
Peter, M.5
Bowerman, B.6
-
86
-
-
2442529664
-
Cullin-based ubiquitin ligases: Cul3-BTB complexes join the family
-
Pintard L, Willems A, Peter M (2004) Cullin-based ubiquitin ligases: Cul3-BTB complexes join the family. EMBO J 23: 1681-1687
-
(2004)
EMBO J
, vol.23
, pp. 1681-1687
-
-
Pintard, L.1
Willems, A.2
Peter, M.3
-
87
-
-
0141493448
-
The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase
-
Pintard L, Willis JH, Willems A, Johnson JL, Srayko M, Kurz T, Glaser S, Mains PE, Tyers M, Bowerman B, Peter M (2003b) The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase. Nature 425: 311-316
-
(2003)
Nature
, vol.425
, pp. 311-316
-
-
Pintard, L.1
Willis, J.H.2
Willems, A.3
Johnson, J.L.4
Srayko, M.5
Kurz, T.6
Glaser, S.7
Mains, P.E.8
Tyers, M.9
Bowerman, B.10
Peter, M.11
-
88
-
-
82755166980
-
Modulation of phototropic responsiveness in Arabidopsis through ubiquitination of phototropin 1 by the CUL3-Ring E3 ubiquitin ligase CRL3(NPH3)
-
Roberts D, Pedmale UV, Morrow J, Sachdev S, Lechner E, Tang X, Zheng N, Hannink M, Genschik P, Liscum E (2011) Modulation of phototropic responsiveness in Arabidopsis through ubiquitination of phototropin 1 by the CUL3-Ring E3 ubiquitin ligase CRL3(NPH3). Plant Cell 23: 3627-3640
-
(2011)
Plant Cell
, vol.23
, pp. 3627-3640
-
-
Roberts, D.1
Pedmale, U.V.2
Morrow, J.3
Sachdev, S.4
Lechner, E.5
Tang, X.6
Zheng, N.7
Hannink, M.8
Genschik, P.9
Liscum, E.10
-
89
-
-
53349121021
-
Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugation
-
Saha A, Deshaies RJ (2008) Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugation. Mol Cell 32: 21-31
-
(2008)
Mol Cell
, vol.32
, pp. 21-31
-
-
Saha, A.1
Deshaies, R.J.2
-
90
-
-
0034143442
-
RPT2 A signal transducer of the phototropic response in Arabidopsis
-
Sakai T, Wada T, Ishiguro S, Okada K (2000) RPT2. A signal transducer of the phototropic response in Arabidopsis. Plant Cell 12: 225-236
-
(2000)
Plant Cell
, vol.12
, pp. 225-236
-
-
Sakai, T.1
Wada, T.2
Ishiguro, S.3
Okada, K.4
-
91
-
-
84861221950
-
KBTBD13 interacts with Cullin 3 to form a functional ubiquitin ligase
-
Sambuughin N, Swietnicki W, Techtmann S, Matrosova V, Wallace T, Goldfarb L, Maynard E (2012) KBTBD13 interacts with Cullin 3 to form a functional ubiquitin ligase. Biochem Biophys Res Commun 421: 743-749
-
(2012)
Biochem Biophys Res Commun
, vol.421
, pp. 743-749
-
-
Sambuughin, N.1
Swietnicki, W.2
Techtmann, S.3
Matrosova, V.4
Wallace, T.5
Goldfarb, L.6
Maynard, E.7
-
92
-
-
78649796274
-
Dominant mutations in KBTBD13, a member of the BTB/ Kelch family, cause nemaline myopathy with cores
-
Sambuughin N, Yau KS, Olive M, Duff RM, Bayarsaikhan M, Lu S, Gonzalez-Mera L, Sivadorai P, Nowak KJ, Ravenscroft G, Mastaglia FL, North KN, Ilkovski B, Kremer H, Lammens M, van Engelen BG, Fabian V, Lamont P, Davis MR, Laing NG et al (2010) Dominant mutations in KBTBD13, a member of the BTB/ Kelch family, cause nemaline myopathy with cores. Am J Hum Genet 87: 842-847
-
(2010)
Am J Hum Genet
, vol.87
, pp. 842-847
-
-
Sambuughin, N.1
Yau, K.S.2
Olive, M.3
Duff, R.M.4
Bayarsaikhan, M.5
Lu, S.6
Gonzalez-Mera, L.7
Sivadorai, P.8
Nowak, K.J.9
Ravenscroft, G.10
Mastaglia, F.L.11
North, K.N.12
Ilkovski, B.13
Kremer, H.14
Lammens, M.15
Van Engelen, B.G.16
Fabian, V.17
Lamont, P.18
Davis, M.R.19
Laing, N.G.20
more..
-
93
-
-
67649511007
-
Recent advances and emerging trends in plant hormone signalling
-
Santner A, Estelle M (2009) Recent advances and emerging trends in plant hormone signalling. Nature 459: 1071-1078
-
(2009)
Nature
, vol.459
, pp. 1071-1078
-
-
Santner, A.1
Estelle, M.2
-
94
-
-
54049134768
-
The cullin7 E3 ubiquitin ligase: A novel player in growth control
-
Sarikas A, Xu X, Field LJ, Pan ZQ (2008) The cullin7 E3 ubiquitin ligase: a novel player in growth control. Cell Cycle 7: 3154-3161
-
(2008)
Cell Cycle
, vol.7
, pp. 3154-3161
-
-
Sarikas, A.1
Xu, X.2
Field, L.J.3
Pan, Z.Q.4
-
95
-
-
33644866769
-
KEL-8 is a substrate receptor for CUL3- dependent ubiquitin ligase that regulates synaptic glutamate receptor turnover
-
Schaefer H, Rongo C (2006) KEL-8 is a substrate receptor for CUL3- dependent ubiquitin ligase that regulates synaptic glutamate receptor turnover. Mol Biol Cell 17: 1250-1260
-
(2006)
Mol Biol Cell
, vol.17
, pp. 1250-1260
-
-
Schaefer, H.1
Rongo, C.2
-
96
-
-
80555131132
-
Nterminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex
-
Scott DC, Monda JK, Bennett EJ, Harper JW, Schulman BA (2011) Nterminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex. Science 334: 674-678
-
(2011)
Science
, vol.334
, pp. 674-678
-
-
Scott, D.C.1
Monda, J.K.2
Bennett, E.J.3
Harper, J.W.4
Schulman, B.A.5
-
97
-
-
77956500977
-
A dual E3 mechanism for Rub1 ligation to Cdc53
-
Scott DC, Monda JK, Grace CR, Duda DM, Kriwacki RW, Kurz T, Schulman BA (2010) A dual E3 mechanism for Rub1 ligation to Cdc53. Mol Cell 39: 784-796
-
(2010)
Mol Cell
, vol.39
, pp. 784-796
-
-
Scott, D.C.1
Monda, J.K.2
Grace, C.R.3
Duda, D.M.4
Kriwacki, R.W.5
Kurz, T.6
Schulman, B.A.7
-
98
-
-
51649130168
-
Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy
-
Shibata T, Ohta T, Tong KI, Kokubu A, Odogawa R, Tsuta K, Asamura H, Yamamoto M, Hirohashi S (2008) Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy. Proc Natl Acad Sci USA 105: 13568-13573
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13568-13573
-
-
Shibata, T.1
Ohta, T.2
Tong, K.I.3
Kokubu, A.4
Odogawa, R.5
Tsuta, K.6
Asamura, H.7
Yamamoto, M.8
Hirohashi, S.9
-
99
-
-
84877340391
-
Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4
-
Shibata S, Zhang J, Puthumana J, Stone KL, Lifton RP (2013) Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4. Proc Natl Acad Sci USA 110: 7838-7843
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 7838-7843
-
-
Shibata, S.1
Zhang, J.2
Puthumana, J.3
Stone, K.L.4
Lifton, R.P.5
-
100
-
-
0033568639
-
Cullin-3 targets cyclin e for ubiquitination and controls S phase in mammalian cells
-
Singer JD, Gurian-West M, Clurman B, Roberts JM (1999) Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells. Genes Dev 13: 2375-2387
-
(1999)
Genes Dev
, vol.13
, pp. 2375-2387
-
-
Singer, J.D.1
Gurian-West, M.2
Clurman, B.3
Roberts, J.M.4
-
101
-
-
33750885385
-
Dysfunctional KEAP1-NRF2 interaction in nonsmall- cell lung cancer
-
Singh A, Misra V, Thimmulappa RK, Lee H, Ames S, Hoque MO, Herman JG, Baylin SB, Sidransky D, Gabrielson E, Brock MV, Biswal S (2006) Dysfunctional KEAP1-NRF2 interaction in nonsmall- cell lung cancer. PLoS Med 3: e420
-
(2006)
PLoS Med
, vol.3
-
-
Singh, A.1
Misra, V.2
Thimmulappa, R.K.3
Lee, H.4
Ames, S.5
Hoque, M.O.6
Herman, J.G.7
Baylin, S.B.8
Sidransky, D.9
Gabrielson, E.10
Brock, M.V.11
Biswal, S.12
-
102
-
-
79955632307
-
Protein phosphatase 2A controls ethylene biosynthesis by differentially regulating the turnover of ACC synthase isoforms
-
Skottke KR, Yoon GM, Kieber JJ, DeLong A (2011) Protein phosphatase 2A controls ethylene biosynthesis by differentially regulating the turnover of ACC synthase isoforms. PLoS Genet 7: e1001370
-
(2011)
PLoS Genet
, vol.7
-
-
Skottke, K.R.1
Yoon, G.M.2
Kieber, J.J.3
Delong, A.4
-
103
-
-
3242665372
-
The ubiquitin 26S proteasome proteolytic pathway
-
Smalle J, Vierstra RD (2004) The ubiquitin 26S proteasome proteolytic pathway. Annu Rev Plant Biol 55: 555-590
-
(2004)
Annu Rev Plant Biol
, vol.55
, pp. 555-590
-
-
Smalle, J.1
Vierstra, R.D.2
-
104
-
-
75149152034
-
A feedback loop mediated by degradation of an inhibitor is required to initiate neuronal differentiation
-
Sobieszczuk DF, Poliakov A, Xu Q, Wilkinson DG (2010) A feedback loop mediated by degradation of an inhibitor is required to initiate neuronal differentiation. Genes Dev 24: 206-218
-
(2010)
Genes Dev
, vol.24
, pp. 206-218
-
-
Sobieszczuk, D.F.1
Poliakov, A.2
Xu, Q.3
Wilkinson, D.G.4
-
105
-
-
65849096454
-
Proteasome-mediated turnover of the transcription coactivator NPR1 plays dual roles in regulating plant immunity
-
Spoel SH, Mou Z, Tada Y, Spivey NW, Genschik P, Dong X (2009) Proteasome-mediated turnover of the transcription coactivator NPR1 plays dual roles in regulating plant immunity. Cell 137: 860-872
-
(2009)
Cell
, vol.137
, pp. 860-872
-
-
Spoel, S.H.1
Mou, Z.2
Tada, Y.3
Spivey, N.W.4
Genschik, P.5
Dong, X.6
-
106
-
-
84863985738
-
A homozygous mutation in KCTD7 links neuronal ceroid lipofuscinosis to the ubiquitin-proteasome system
-
Staropoli JF, Karaa A, Lim ET, Kirby A, Elbalalesy N, Romansky SG, Leydiker KB, Coppel SH, Barone R, Xin W, MacDonald ME, Abdenur JE, Daly MJ, Sims KB, Cotman SL (2012) A homozygous mutation in KCTD7 links neuronal ceroid lipofuscinosis to the ubiquitin-proteasome system. Am J Hum Genet 91: 202-208
-
(2012)
Am J Hum Genet
, vol.91
, pp. 202-208
-
-
Staropoli, J.F.1
Karaa, A.2
Lim, E.T.3
Kirby, A.4
Elbalalesy, N.5
Romansky, S.G.6
Leydiker, K.B.7
Coppel, S.H.8
Barone, R.9
Xin, W.10
Macdonald, M.E.11
Abdenur, J.E.12
Daly, M.J.13
Sims, K.B.14
Cotman, S.L.15
-
107
-
-
34548105127
-
Sequence and structural analysis of BTB domain proteins
-
Stogios PJ, Downs GS, Jauhal JJ, Nandra SK, Prive GG (2005) Sequence and structural analysis of BTB domain proteins. Genome Biol 6: R82
-
(2005)
Genome Biol
, vol.6
-
-
Stogios, P.J.1
Downs, G.S.2
Jauhal, J.J.3
Nandra, S.K.4
Prive, G.G.5
-
108
-
-
34249305132
-
A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells
-
Sumara I, Quadroni M, Frei C, Olma MH, Sumara G, Ricci R, Peter M (2007) A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells. Dev Cell 12: 887-900
-
(2007)
Dev Cell
, vol.12
, pp. 887-900
-
-
Sumara, I.1
Quadroni, M.2
Frei, C.3
Olma, M.H.4
Sumara, G.5
Ricci, R.6
Peter, M.7
-
109
-
-
78751703950
-
Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
-
Taguchi K, Motohashi H, Yamamoto M (2011) Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution. Genes Cells 16: 123-140
-
(2011)
Genes Cells
, vol.16
, pp. 123-140
-
-
Taguchi, K.1
Motohashi, H.2
Yamamoto, M.3
-
110
-
-
27644538063
-
Arabidopsis CUL3A and CUL3B genes are essential for normal embryogenesis
-
Thomann A, Brukhin V, Dieterle M, Gheyeselinck J, Vantard M, Grossniklaus U, Genschik P (2005) Arabidopsis CUL3A and CUL3B genes are essential for normal embryogenesis. Plant J 43: 437-448
-
(2005)
Plant J
, vol.43
, pp. 437-448
-
-
Thomann, A.1
Brukhin, V.2
Dieterle, M.3
Gheyeselinck, J.4
Vantard, M.5
Grossniklaus, U.6
Genschik, P.7
-
111
-
-
59249106806
-
Arabidopsis CULLIN3 genes regulate primary root growth and patterning by ethylenedependent and -independent mechanisms
-
Thomann A, Lechner E, Hansen M, Dumbliauskas E, Parmentier Y, Kieber J, Scheres B, Genschik P (2009) Arabidopsis CULLIN3 genes regulate primary root growth and patterning by ethylenedependent and -independent mechanisms. PLoS Genet 5: e1000328
-
(2009)
PLoS Genet
, vol.5
-
-
Thomann, A.1
Lechner, E.2
Hansen, M.3
Dumbliauskas, E.4
Parmentier, Y.5
Kieber, J.6
Scheres, B.7
Genschik, P.8
-
112
-
-
33746771082
-
Adaptive evolution in two large families of ubiquitin-ligase adapters in nematodes and plants
-
Thomas JH (2006) Adaptive evolution in two large families of ubiquitin-ligase adapters in nematodes and plants. Genome Res 16: 1017-1030
-
(2006)
Genome Res
, vol.16
, pp. 1017-1030
-
-
Thomas, J.H.1
-
113
-
-
80052268120
-
Genetic disruption of KEAP1/CUL3 E3 ubiquitin ligase complex components is a key mechanism of NF-kappaB pathway activation in lung cancer
-
Thu KL, Pikor LA, Chari R, Wilson IM, Macaulay CE, English JC, Tsao MS, Gazdar AF, Lam S, Lam WL, Lockwood WW (2011) Genetic disruption of KEAP1/CUL3 E3 ubiquitin ligase complex components is a key mechanism of NF-kappaB pathway activation in lung cancer. J Thorac Oncol 6: 1521-1529
-
(2011)
J Thorac Oncol
, vol.6
, pp. 1521-1529
-
-
Thu, K.L.1
Pikor, L.A.2
Chari, R.3
Wilson, I.M.4
Macaulay, C.E.5
English, J.C.6
Tsao, M.S.7
Gazdar, A.F.8
Lam, S.9
Lam, W.L.10
Lockwood, W.W.11
-
114
-
-
34447522241
-
Mutation of a potassium channel-related gene in progressive myoclonic epilepsy
-
Van Bogaert P, Azizieh R, Desir J, Aeby A, De Meirleir L, Laes JF, Christiaens F, Abramowicz MJ (2007) Mutation of a potassium channel-related gene in progressive myoclonic epilepsy. Ann Neurol 61: 579-586
-
(2007)
Ann Neurol
, vol.61
, pp. 579-586
-
-
Van Bogaert, P.1
Azizieh, R.2
Desir, J.3
Aeby, A.4
De Meirleir, L.5
Laes, J.F.6
Christiaens, F.7
Abramowicz, M.J.8
-
115
-
-
84855183210
-
Arabidopsis alpha Aurora kinases function in formative cell division plane orientation
-
Van Damme D, De Rybel B, Gudesblat G, Demidov D, GrunewaldW, De Smet I, Houben A, Beeckman T, Russinova E (2011) Arabidopsis alpha Aurora kinases function in formative cell division plane orientation. Plant Cell 23: 4013-4024
-
(2011)
Plant Cell
, vol.23
, pp. 4013-4024
-
-
Van Damme, D.1
De Rybel, B.2
Gudesblat, G.3
Demidov, D.4
Grunewald, W.5
De Smet, I.6
Houben, A.7
Beeckman, T.8
Russinova, E.9
-
116
-
-
0026068805
-
Naming a targeting signal
-
Varshavsky A (1991) Naming a targeting signal. Cell 64: 13-15
-
(1991)
Cell
, vol.64
, pp. 13-15
-
-
Varshavsky, A.1
-
117
-
-
84875813488
-
Impaired KLHL3-mediated ubiquitination of WNK4 causes human hypertension
-
Wakabayashi M, Mori T, Isobe K, Sohara E, Susa K, Araki Y, Chiga M, Kikuchi E, Nomura N, Mori Y, Matsuo H, Murata T, Nomura S, Asano T, Kawaguchi H, Nonoyama S, Rai T, Sasaki S, Uchida S (2013) Impaired KLHL3-mediated ubiquitination of WNK4 causes human hypertension. Cell Rep 3: 858-868
-
(2013)
Cell Rep
, vol.3
, pp. 858-868
-
-
Wakabayashi, M.1
Mori, T.2
Isobe, K.3
Sohara, E.4
Susa, K.5
Araki, Y.6
Chiga, M.7
Kikuchi, E.8
Nomura, N.9
Mori, Y.10
Matsuo, H.11
Murata, T.12
Nomura, S.13
Asano, T.14
Kawaguchi, H.15
Nonoyama, S.16
Rai, T.17
Sasaki, S.18
Uchida, S.19
-
118
-
-
1242296811
-
Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers
-
Wakabayashi N, Dinkova-Kostova AT, Holtzclaw WD, Kang MI, Kobayashi A, Yamamoto M, Kensler TW, Talalay P (2004) Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers. Proc Natl Acad Sci USA 101: 2040-2045
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2040-2045
-
-
Wakabayashi, N.1
Dinkova-Kostova, A.T.2
Holtzclaw, W.D.3
Kang, M.I.4
Kobayashi, A.5
Yamamoto, M.6
Kensler, T.W.7
Talalay, P.8
-
119
-
-
2342482400
-
Regulation of ethylene gas biosynthesis by the Arabidopsis ETO1 protein
-
Wang KL, Yoshida H, Lurin C, Ecker JR (2004) Regulation of ethylene gas biosynthesis by the Arabidopsis ETO1 protein. Nature 428: 945-950
-
(2004)
Nature
, vol.428
, pp. 945-950
-
-
Wang, K.L.1
Yoshida, H.2
Lurin, C.3
Ecker, J.R.4
-
120
-
-
18744416577
-
Arabidopsis AtCUL3a and AtCUL3b form complexes with members of the BTB/POZ-MATH protein family
-
Weber H, Bernhardt A, Dieterle M, Hano P, Mutlu A, Estelle M, Genschik P, Hellmann H (2005) Arabidopsis AtCUL3a and AtCUL3b form complexes with members of the BTB/POZ-MATH protein family. Plant Physiol 137: 83-93
-
(2005)
Plant Physiol
, vol.137
, pp. 83-93
-
-
Weber, H.1
Bernhardt, A.2
Dieterle, M.3
Hano, P.4
Mutlu, A.5
Estelle, M.6
Genschik, P.7
Hellmann, H.8
-
121
-
-
0037457965
-
Molecular pathogenesis of inherited hypertension with hyperkalemia: The Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4
-
Wilson FH, Kahle KT, Sabath E, Lalioti MD, Rapson AK, Hoover RS, Hebert SC, Gamba G, Lifton RP (2003) Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4. Proc Natl Acad Sci USA 100: 680-684
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 680-684
-
-
Wilson, F.H.1
Kahle, K.T.2
Sabath, E.3
Lalioti, M.D.4
Rapson, A.K.5
Hoover, R.S.6
Hebert, S.C.7
Gamba, G.8
Lifton, R.P.9
-
122
-
-
84875777183
-
CAND1 controls in vivo dynamics of the cullin 1-RING ubiquitin ligase repertoire
-
Wu S, Zhu W, Nhan T, Toth JI, Petroski MD, Wolf DA (2013) CAND1 controls in vivo dynamics of the cullin 1-RING ubiquitin ligase repertoire. Nat Commun 4: 1642
-
(2013)
Nat Commun
, vol.4
, pp. 1642
-
-
Wu, S.1
Zhu, W.2
Nhan, T.3
Toth, J.I.4
Petroski, M.D.5
Wolf, D.A.6
-
123
-
-
0141493447
-
BTB proteins are substrate-specific adaptors in an SCFlike modular ubiquitin ligase containing CUL-3
-
Xu L,Wei Y, Reboul J, Vaglio P, Shin TH, Vidal M, Elledge SJ, Harper JW (2003) BTB proteins are substrate-specific adaptors in an SCFlike modular ubiquitin ligase containing CUL-3. Nature 425: 316-321
-
(2003)
Nature
, vol.425
, pp. 316-321
-
-
Xu Lwei, Y.1
Reboul, J.2
Vaglio, P.3
Shin, T.H.4
Vidal, M.5
Elledge, S.J.6
Harper, J.W.7
-
124
-
-
84862979524
-
Translational homeostasis via the mRNA cap-binding protein, eIF4E
-
Yanagiya A, Suyama E, Adachi H, Svitkin YV, Aza-Blanc P, Imataka H, Mikami S, Martineau Y, Ronai ZA, Sonenberg N (2012) Translational homeostasis via the mRNA cap-binding protein, eIF4E. Mol Cell 46: 847-858
-
(2012)
Mol Cell
, vol.46
, pp. 847-858
-
-
Yanagiya, A.1
Suyama, E.2
Adachi, H.3
Svitkin, Y.V.4
Aza-Blanc, P.5
Imataka, H.6
Mikami, S.7
Martineau, Y.8
Ronai, Z.A.9
Sonenberg, N.10
-
125
-
-
55849133733
-
Identification of SCF ubiquitin ligase substrates by global protein stability profiling
-
Yen HC, Elledge SJ (2008) Identification of SCF ubiquitin ligase substrates by global protein stability profiling. Science 322: 923-929
-
(2008)
Science
, vol.322
, pp. 923-929
-
-
Yen, H.C.1
Elledge, S.J.2
-
126
-
-
80051583598
-
A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progression
-
Yuan WC, Lee YR, Huang SF, Lin YM, Chen TY, Chung HC, Tsai CH, Chen HY, Chiang CT, Lai CK, Lu LT, Chen CH, Gu DL, Pu YS, Jou YS, Lu KP, Hsiao PW, Shih HM, Chen RH (2011) A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progression. Cancer Cell 20: 214-228
-
(2011)
Cancer Cell
, vol.20
, pp. 214-228
-
-
Yuan, W.C.1
Lee, Y.R.2
Huang, S.F.3
Lin, Y.M.4
Chen, T.Y.5
Chung, H.C.6
Tsai, C.H.7
Chen, H.Y.8
Chiang, C.T.9
Lai, C.K.10
Lu, L.T.11
Chen, C.H.12
Gu, D.L.13
Pu, Y.S.14
Jou, Y.S.15
Lu, K.P.16
Hsiao, P.W.17
Shih, H.M.18
Chen, R.H.19
-
127
-
-
84875768399
-
CSN-and CAND1-dependent remodelling of the budding yeast SCF complex
-
Zemla A, Thomas Y, Kedziora S, Knebel A, Wood NT, Rabut G, Kurz T (2013) CSN- and CAND1-dependent remodelling of the budding yeast SCF complex. Nat Commun 4: 1641
-
(2013)
Nat Commun
, vol.4
, pp. 1641
-
-
Zemla, A.1
Thomas, Y.2
Kedziora, S.3
Knebel, A.4
Wood, N.T.5
Rabut, G.6
Kurz, T.7
-
128
-
-
77957354348
-
Plant stomata: A checkpoint of host immunity and pathogen virulence
-
Zeng W, Melotto M, He SY (2010) Plant stomata: a checkpoint of host immunity and pathogen virulence. Curr Opin Biotechnol 21: 599-603
-
(2010)
Curr Opin Biotechnol
, vol.21
, pp. 599-603
-
-
Zeng, W.1
Melotto, M.2
He, S.Y.3
-
129
-
-
10044228504
-
Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex
-
Zhang DD, Lo SC, Cross JV, Templeton DJ, Hannink M (2004) Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex. Mol Cell Biol 24: 10941-10953
-
(2004)
Mol Cell Biol
, vol.24
, pp. 10941-10953
-
-
Zhang, D.D.1
Lo, S.C.2
Cross, J.V.3
Templeton, D.J.4
Hannink, M.5
-
130
-
-
75849129292
-
Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase
-
Zhang Q, Shi Q, Chen Y, Yue T, Li S,Wang B, Jiang J (2009) Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase. Proc Natl Acad Sci USA 106: 21191-21196
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 21191-21196
-
-
Zhang, Q.1
Shi, Q.2
Chen, Y.3
Yue, T.4
Li Swang, B.5
Jiang, J.6
-
131
-
-
33646893705
-
A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor
-
Zhang Q, Zhang L, Wang B, Ou CY, Chien CT, Jiang J (2006) A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor. Dev Cell 10: 719-729
-
(2006)
Dev Cell
, vol.10
, pp. 719-729
-
-
Zhang, Q.1
Zhang, L.2
Wang, B.3
Ou, C.Y.4
Chien, C.T.5
Jiang, J.6
-
132
-
-
70349769327
-
Structures of SPOP-substrate complexes: Insights into molecular architectures of BTB-Cul3 ubiquitin ligases
-
Zhuang M, Calabrese MF, Liu J,Waddell MB, Nourse A, Hammel M, Miller DJ, Walden H, Duda DM, Seyedin SN, Hoggard T, Harper JW, White KP, Schulman BA (2009) Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. Mol Cell 36: 39-50
-
(2009)
Mol Cell
, vol.36
, pp. 39-50
-
-
Zhuang, M.1
Calabrese, M.F.2
Liu Jwaddell, M.B.3
Nourse, A.4
Hammel, M.5
Miller, D.J.6
Walden, H.7
Duda, D.M.8
Seyedin, S.N.9
Hoggard, T.10
Harper, J.W.11
White, K.P.12
Schulman, B.A.13
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