Cullins and cell cycle control

Protoplasma

Volumn 211, Issue 1-2, 2000, Pages 20-28

  Gieffers, C ^a   Schleiffer, A ^a   Peters, J M ^a  

^a RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

Author keywords

Anaphase promoting complex; Proteolysis; Skp1 cullin F box complex; Ubiquitin; Von Hippel Lindau tumor suppressor

Indexed keywords

ANAPHASE PROMOTING COMPLEX; CAENORHABDITIS ELEGANS; CELL CYCLE; CELL PROLIFERATION; CUL 1 PROTEIN; CULLIN; GENETIC CONSERVATION; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; PROTEIN SUBUNIT; SKP1 CULLIN F BOX COMPLEX; UBIQUITIN;

EID: 0034031236     PISSN: 0033183X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01279896     Document Type: Article

References (53)

1. Bai C, Sen P, Hofmann K, Ma L, Goebl M, Harper JW, Elledge SJ (1996) SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box. Cell 86: 263-274
2. Barral Y, Jentsch S, Mann C (1995) G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast. Genes Dev 9: 399-409
3. Byrd PJ, Stankovic T, McConville CM, Smith AD, Cooper PR, Taylor AM (1997) Identification and analysis of expression of human VACM-1, a cullin gene family member located on chromosome 11q22-23. Genome Res 7: 71-75
4. Chen LC, Manjeshwar S, Lu Y, Moore D, Ljung BM, Kuo WL, Dairkee SH, Wernick M, Collins C, Smith HS (1998) The human homologue for the Caenorhabditis elegans cul-4 gene is amplified and overexpressed in primary breast cancers. Cancer Res 58: 3677-3683
5. Clurman BE, Sheaff RJ, Thress K, Groudine M, Roberts JM (1996) Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation. Genes Dev 10: 1979-1990
6. Cohen-Fix O, Peters JM, Kirschner MW, Koshland D (1996) Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1 p. Genes Dev 10: 3081-3093
7. Diehl JA, Zindy F, Sherr CJ (1997) Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway. Genes Dev 11: 957-972
8. Du M, Sansores-Garcia L, Zu Z, Wu KK (1998) Cloning and expression analysis of a novel salicylate suppressible gene, Hs-CUL-3, a member of cullin/Cdc53 family. J Biol Chem 273: 24289-24292
9. Duan DR, Pause A, Burgess WH, Aso T, Chen DY, Garrett KP, Conaway RC, Conaway JW, Linehan WM, Klausner RD (1995) Inhibition of transcription elongation by the VHL tumor suppressor protein. Science 269: 1402-1406
10. Fang G, Yu H, Kirschner MW (1998) Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1. Mol Cell 2: 163-171
11. Feldman RM, Correll CC, Kaplan KB, Deshaies RJ (1997) A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p. Cell 91: 221-230
12. Funabiki H, Yamano H, Kumada K, Nagao K, Hunt T, Yanagida M (1996) Cut2 proteolysis required for sister-chromatid separation in fission yeast. Nature 381: 438-441
13. Garrett KP, Aso T, Bradsher JN, Foundling SI, Lane WS, Conaway RC, Conaway JW (1995) Positive regulation of general transcription factor SIII by a tailed ubiquitin homolog. Proc Natl Acad Sci USA 92: 7172-7176
14. Grossberger R, Gieffers C, Zachariae W, Podtelejnikov AY, Schleifer A, Nasmyth K, Mann M, Peters JM (1999) Characterization of the DOC1/APC10 subunit of the yeast and human anaphase-promoting complex. J Biol Chem 274: 14500-14507
15. Hochstrasser M (1996) Ubiquitin-dependent protein degradation. Annu Rev Genet 30: 405-439
16. -(1998) There's the rub: a novel ubiquitin-like modification linked to cell cycle regulation. Genes Dev 12: 901-907
17. Iliopoulos O, Kibel A, Gray S, Kaelin WG Jr (1995) Tumour suppression by the human von Hippel-Lindau gene product. Nat Med 1: 822-826
18. -Levy AP, Jiang C, Kaelin WG Jr, Goldberg MA (1996) Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein. Proc Natl Acad Sci USA 93: 10595-10599
19. Irniger S, Piatti S, Michaelis C, Nasmyth K (1995) Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast. Cell 81: 269-278 (Erratum, 93: 487, 1998)
20. Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (1998) Prediction of the coding sequences of unidentified human genes X: the complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res 5: 169-176
21. Kaiser P, Sia RA, Bardes EG, Lew DJ, Reed SI (1998) Cdc34 and the F-box protein Met30 are required for degradation of the Cdk-inhibitory kinase Swe1. Genes Dev 12: 2587-2597
22. Kibel A, Iliopoulos O, DeCaprio JA, Kaelin WG Jr (1995) Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C. Science 269: 1444-1446
23. King RW, Peters JM, Tugendreich S, Rolfe M, Hieter P, Kirschner MW (1995) A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell 81: 279-288
24. Kipreos ET, Lander LE, Wing JP, He WW, Hedgecock EM (1996) cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. Cell 85: 829-839
25. Kominami K, Seth-Smith H, Toda T (1998) Apc10 and Ste9/Srw1, two regulators of the APC-cyclosome, as well as the CDK inhibitor Rum1 are required for G1 cell-cycle arrest in fission yeast. EMBO J 17: 5388-5399
26. Kramer ER, Gieffers C, Holzl G, Hengstschlager M, Peters JM (1998) Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family. Curr Biol 8: 1207-10
27. Krek W (1998) Proteolysis and the G1-S transition: the SCF connection. Curr Opin Genet Dev 1: 36-42
28. Lammer D, Mathias N, Laplaza JM, Jiang W, Liu Y, Callis J, Goebl M, Estelle M (1998) Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev 12: 914-926
29. Latif F, Tory K, Gnarra J, Yao M, Duh FM, Orcutt ML, Stackhouse T, Kuzmin I, Modi W, Geil L, Schmidt L, Zhou F, Li H, Wei MH, Chen F, Glenn G, Choyke P, Walther MM, Weng Y, Duan D-S, Dean M, Glavač D, Richards FM, Crossey PA, Ferguson-Smith MA, Le Paslier D, Chumakov I, Cohen D, Chinault AC, Maher ER, Linehan WM, Zbar B, Lerman MI (1993) Identification of the von Hippel-Lindau disease tumor suppressor gene. Science 260: 1317-1320
30. Lehman AL, Nakatsu Y, Ching A, Bronson RT, Oakey RJ, Keiper-Hrynko N, Finger JN, Durham-Pierre D, Horton DB, Newton JM, Lyon MF, Brilliant MH (1998) A very large protein with diverse functional motifs is deficient in rjs (runty, jerky, sterile) mice. Proc Natl Acad Sci USA 95: 9436-9441
31. Liakopoulos D, Doenges G, Matuschewski K, Jentsch S (1998) A novel protein modification pathway related to the ubiquitin system. EMBO J 17: 2208-2214
32. Lisztwan J, Marti A, Sutterluty H, Gstaiger M, Wirbelauer C, Krek W (1998) Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway. EMBO J 17: 368-383
33. Lyapina SA, Correll CC, Kipreos ET, Deshaies RJ (1998) Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein. Proc Natl Acad Sci USA 95: 7451-7456
34. Maki CG, Howley PM (1997) Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation. Mol Cell Biol 17: 355-363
35. SKP2 ubiquitin-protein ligase and E2F-1 underlies regulation of E2F-1 degradation. Nat Med 1: 14-18
36. 1-to-S phase transition and identifies a conserved family of proteins. Mol Cell Biol 16: 6634-6643
37. North WG, Fay MJ, Longo KA, Du J (1998) Expression of all known vasopressin receptor subtypes by small cell tumors implies a multifaceted role for this neuropeptide. Cancer Res 58: 1866-1871
38. Ohh M, Yauch RL, Lonergan KM, Whaley JM, Stemmer-Rachamimov AO, Louis DN, Gavin BJ, Kley N, Kaelin WG Jr, Iliopoulos O (1998) The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix. Mol Cell 1: 959-968
39. Osaka F, Kawasaki H, Aida N, Saeki M, Chiba T, Kawashima S, Tanaka K, Kato S (1998) A new NEDD8-ligating system for cullin-4A. Genes Dev 12: 2263-2268
40. Patton EE, Willems AR, Sa D, Kuras L, Thomas D, Craig KL, Tyers M (1998a) Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box protein complexes that regulate cell division and methionine biosynthesis in yeast. Genes Dev 12: 692-705
41. -Tyers M (1998b) Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis. Trends Genet 14: 236-243
42. Pause A, Lee S, Worrell RA, Chen DY, Burgess WH, Linehan WM, Klausner RD (1997) The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins. Proc Natl Acad Sci USA 94: 2156-2161
43. -Lonergan KM, Klausner RD (1998) The von Hippel-Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal. Proc Natl Acad Sci USA 95: 993-998
44. Peters JM (1998) SCF and APC: the Yin and Yang of cell cycle regulated proteolysis. Curr Opin Cell Biol 10: 759-768
45. Scheffner M, Smith S, Jentsch S (1998) The ubiquitin-conjugation system. In: Peters JM, Harris R, Finley D (eds) Ubiquitin and the biology of the cell. Plenum, New York, pp 65-91
46. Schwob E, Bohm T, Mendenhall MD, Nasmyth K (1994) The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae. Cell 79: 233-244
47. Skowyra D, Craig KL, Tyers M, Elledge SJ, Harper JW (1997) F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell 91: 209-219
48. Sudakin V, Ganoth D, Dahan A, Heller H, Hershko J, Luca FC, Ruderman JV, Hershko H (1995) The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis. Mol Biol Cell 6: 185-197
49. Verma R, Annan RS, Huddleston MJ, Carr SA, Reynard G, Deshaies RJ (1997) Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase. Science 278: 455-460
50. Visintin R, Prinz S, Amon A (1997) CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis. Science 278: 460-463
51. Yu H, Peters JM, King RW, Page AW, Hieter P, Kirschner MW (1998) Identification of a cullin homology region in a subunit of the anaphase-promoting complex. Science 279: 1219-1222
52. Zachariae W, Shevchenko A, Andrews PD, Ciosk R, Galova M, Stark MJ, Mann M, Nasmyth K (1998a) Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins. Science 279: 1216-1219
53. -Schwab M, Nasmyth K, Seufert W (1998b) Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex. Science 282: 1721-1724