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Volumn , Issue , 2013, Pages

The proapoptotic effect of traditional and novel nonsteroidal anti-inflammatory drugs in mammalian and yeast cells

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-PROLIFERATIVE; ANTINEOPLASTIC; CANCER PREVENTION; CHEMOPREVENTIVE; CYCLOOXYGENASES; MAMMALIAN CELL LINES; NONSTEROIDAL ANTI-INFLAMMATORY DRUGS; PRO-APOPTOTIC EFFECTS;

EID: 84883150831     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2013/504230     Document Type: Article
Times cited : (16)

References (187)
  • 1
    • 0034009433 scopus 로고    scopus 로고
    • Nonsteroidal. Anti-inflammatory drugs and cancer prevention
    • 2-s2.0-0034009433 10.1146/annurev.med.51.1.511
    • Baron J. A., Sandler R. S., Nonsteroidal. anti-inflammatory drugs and cancer prevention. Annual Review of Medicine 2000 51 511 523 2-s2.0-0034009433 10.1146/annurev.med.51.1.511
    • (2000) Annual Review of Medicine , vol.51 , pp. 511-523
    • Baron, J.A.1    Sandler, R.S.2
  • 3
    • 78650215449 scopus 로고    scopus 로고
    • Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials
    • 2-s2.0-78650215449 10.1016/S0140-6736(10)61543-7
    • Rothwell P. M., Wilson M., Elwin C.-E., Norrving B., Algra A., Warlow C. P., Meade T. W., Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials. The Lancet 2010 376 9754 1741 1750 2-s2.0-78650215449 10.1016/S0140-6736(10)61543-7
    • (2010) The Lancet , vol.376 , Issue.9754 , pp. 1741-1750
    • Rothwell, P.M.1    Wilson, M.2    Elwin, C.-E.3    Norrving, B.4    Algra, A.5    Warlow, C.P.6    Meade, T.W.7
  • 4
    • 78650825618 scopus 로고    scopus 로고
    • Effect of daily aspirin on long-term risk of death due to cancer: Analysis of individual patient data from randomised trials
    • 2-s2.0-78650825618 10.1016/S0140-6736(10)62110-1
    • Rothwell P. M., Fowkes F. G. R., Belch J. F., Ogawa H., Warlow C. P., Meade T. W., Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials. The Lancet 2011 377 9759 31 41 2-s2.0-78650825618 10.1016/S0140-6736(10)62110-1
    • (2011) The Lancet , vol.377 , Issue.9759 , pp. 31-41
    • Rothwell, P.M.1    Fowkes, F.G.R.2    Belch, J.F.3    Ogawa, H.4    Warlow, C.P.5    Meade, T.W.6
  • 5
    • 0027941910 scopus 로고
    • Nonsteroidal antiinflammatory agents in chemoprevention of colorectal cancer: At what cost?
    • 2-s2.0-0027941910 10.1007/BF02090382
    • Trujillo M. A., Garewal H. S., Sampliner R. E., Nonsteroidal antiinflammatory agents in chemoprevention of colorectal cancer: at what cost? Digestive Diseases and Sciences 1994 39 10 2260 2266 2-s2.0-0027941910 10.1007/BF02090382
    • (1994) Digestive Diseases and Sciences , vol.39 , Issue.10 , pp. 2260-2266
    • Trujillo, M.A.1    Garewal, H.S.2    Sampliner, R.E.3
  • 6
    • 0029115954 scopus 로고
    • Sulindac sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cells
    • 2-s2.0-0029115954
    • Shiff S. J., Qiao L., Tsai L.-L., Rigas B., Sulindac sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cells. Journal of Clinical Investigation 1995 96 1 491 503 2-s2.0-0029115954
    • (1995) Journal of Clinical Investigation , vol.96 , Issue.1 , pp. 491-503
    • Shiff, S.J.1    Qiao, L.2    Tsai, L.-L.3    Rigas, B.4
  • 8
    • 0034655190 scopus 로고    scopus 로고
    • Sulindac and exisulind exhibit a significant antiproliferative effect and induce apoptosis in human hepatocellular carcinoma cell lines
    • 2-s2.0-0034655190
    • Rahman M. A., Dhar D. K., Masunaga R., Yamanoi A., Kohno H., Nagasue N., Sulindac and exisulind exhibit a significant antiproliferative effect and induce apoptosis in human hepatocellular carcinoma cell lines. Cancer Research 2000 60 8 2085 2089 2-s2.0-0034655190
    • (2000) Cancer Research , vol.60 , Issue.8 , pp. 2085-2089
    • Rahman, M.A.1    Dhar, D.K.2    Masunaga, R.3    Yamanoi, A.4    Kohno, H.5    Nagasue, N.6
  • 9
    • 0020616992 scopus 로고
    • Prolonged antitumor effect of indomethacin on autochthonous intestinal tumors in rats
    • 2-s2.0-0020616992
    • Pollard M., Luckert P. H., Prolonged antitumor effect of indomethacin on autochthonous intestinal tumors in rats. Journal of the National Cancer Institute 1983 70 6 1103 1105 2-s2.0-0020616992
    • (1983) Journal of the National Cancer Institute , vol.70 , Issue.6 , pp. 1103-1105
    • Pollard, M.1    Luckert, P.H.2
  • 10
    • 0033915996 scopus 로고    scopus 로고
    • Discordant effect of aspirin and indomethacin on intestinal tumor burden in Apc(Min/+) mice
    • 2-s2.0-0033915996 10.1054/plef.2000.0154
    • Chiu C. H., McEntee M. F., Whelan J., Discordant effect of aspirin and indomethacin on intestinal tumor burden in Apc(Min/+) mice. Prostaglandins Leukotrienes and Essential Fatty Acids 2000 62 5 269 275 2-s2.0-0033915996 10.1054/plef.2000.0154
    • (2000) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.62 , Issue.5 , pp. 269-275
    • Chiu, C.H.1    McEntee, M.F.2    Whelan, J.3
  • 11
    • 0036387468 scopus 로고    scopus 로고
    • Superior effectiveness of ibuprofen compared with other NSAIDs for reducing the survival of human prostate cancer cells
    • 2-s2.0-0036387468 10.1007/s00280-002-0485-8
    • Andrews J., Djakiew D., Krygier S., Andrews P., Superior effectiveness of ibuprofen compared with other NSAIDs for reducing the survival of human prostate cancer cells. Cancer Chemotherapy and Pharmacology 2002 50 4 277 284 2-s2.0-0036387468 10.1007/s00280-002-0485-8
    • (2002) Cancer Chemotherapy and Pharmacology , vol.50 , Issue.4 , pp. 277-284
    • Andrews, J.1    Djakiew, D.2    Krygier, S.3    Andrews, P.4
  • 12
    • 69049087907 scopus 로고    scopus 로고
    • Association between NSAIDs use and breast cancer risk: A systematic review and meta-analysis
    • 2-s2.0-69049087907 10.1007/s10549-008-0228-6
    • Zhao Y.-S., Zhu S., Li X.-W., Wang F., Hu F.-L., Li D.-D., Zhang W.-C., Li X., Association between NSAIDs use and breast cancer risk: a systematic review and meta-analysis. Breast Cancer Research and Treatment 2009 117 1 141 150 2-s2.0-69049087907 10.1007/s10549-008-0228-6
    • (2009) Breast Cancer Research and Treatment , vol.117 , Issue.1 , pp. 141-150
    • Zhao, Y.-S.1    Zhu, S.2    Li, X.-W.3    Wang, F.4    Hu, F.-L.5    Li, D.-D.6    Zhang, W.-C.7    Li, X.8
  • 14
    • 5644294350 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is expressed in neuroblastoma, and nonsteroidal anti-inflammatory drugs induce apoptosis and inhibit tumor growth in vivo
    • 2-s2.0-5644294350 10.1158/0008-5472.CAN-04-1795
    • Johnsen J. I., Lindskog M., Ponthan F., Pettersen I., Elfman L., Orrego A., Sveinbjörnsson B., Kogner P., Cyclooxygenase-2 is expressed in neuroblastoma, and nonsteroidal anti-inflammatory drugs induce apoptosis and inhibit tumor growth in vivo. Cancer Research 2004 64 20 7210 7215 2-s2.0-5644294350 10.1158/0008-5472.CAN-04-1795
    • (2004) Cancer Research , vol.64 , Issue.20 , pp. 7210-7215
    • Johnsen, J.I.1    Lindskog, M.2    Ponthan, F.3    Pettersen, I.4    Elfman, L.5    Orrego, A.6    Sveinbjörnsson, B.7    Kogner, P.8
  • 17
    • 0035870291 scopus 로고    scopus 로고
    • Nitric oxide-releasing nonsteroidal anti-inflammatory drugs (NSAIDs) alter the kinetics of human colon cancer cell lines more effectively than traditional NSAIDs: Implications for colon cancer chemoprevention
    • 2-s2.0-0035870291
    • Williams J. L., Borgo S., Hasan I., Castillo E., Traganos F., Rigas B., Nitric oxide-releasing nonsteroidal anti-inflammatory drugs (NSAIDs) alter the kinetics of human colon cancer cell lines more effectively than traditional NSAIDs: implications for colon cancer chemoprevention. Cancer Research 2001 61 8 3285 3289 2-s2.0-0035870291
    • (2001) Cancer Research , vol.61 , Issue.8 , pp. 3285-3289
    • Williams, J.L.1    Borgo, S.2    Hasan, I.3    Castillo, E.4    Traganos, F.5    Rigas, B.6
  • 18
    • 0036894884 scopus 로고    scopus 로고
    • Nitric oxide-donating nonsteroidal anti-inflammatory drugs inhibit the growth of various cultured human cancer cells: Evidence of a tissue type-independent effect
    • 2-s2.0-0036894884 10.1124/jpet.102.042754
    • Kashfi K., Ryann Y., Qiao L. L., Williams J. L., Chen J., Del Soldato P., Traganos F., Rigas B., Nitric oxide-donating nonsteroidal anti-inflammatory drugs inhibit the growth of various cultured human cancer cells: evidence of a tissue type-independent effect. Journal of Pharmacology and Experimental Therapeutics 2002 303 3 1273 1282 2-s2.0-0036894884 10.1124/jpet.102.042754
    • (2002) Journal of Pharmacology and Experimental Therapeutics , vol.303 , Issue.3 , pp. 1273-1282
    • Kashfi, K.1    Ryann, Y.2    Qiao, L.L.3    Williams, J.L.4    Chen, J.5    Del Soldato, P.6    Traganos, F.7    Rigas, B.8
  • 19
    • 62349130701 scopus 로고    scopus 로고
    • Phosphoaspirin (MDC-43), a novel benzyl ester of aspirin, inhibits the growth of human cancer cell lines more potently than aspirin: A redox-dependent effect
    • 2-s2.0-62349130701 10.1093/carcin/bgp015
    • Zhao W., Mackenzie G. G., Murray O. T., Zhang Z., Rigas B., Phosphoaspirin (MDC-43), a novel benzyl ester of aspirin, inhibits the growth of human cancer cell lines more potently than aspirin: a redox-dependent effect. Carcinogenesis 2009 30 3 512 519 2-s2.0-62349130701 10.1093/carcin/bgp015
    • (2009) Carcinogenesis , vol.30 , Issue.3 , pp. 512-519
    • Zhao, W.1    Mackenzie, G.G.2    Murray, O.T.3    Zhang, Z.4    Rigas, B.5
  • 20
    • 78149248334 scopus 로고    scopus 로고
    • Phospho-sulindac (OXT-922) inhibits the growth of human colon cancer cell lines: A redox/polyamine-dependent effect
    • 2-s2.0-78149248334 10.1093/carcin/bgq149
    • Huang L., Zhu C., Sun Y., Xie G., Mackenzie G. G., Qiao G., Komninou D., Rigas B., Phospho-sulindac (OXT-922) inhibits the growth of human colon cancer cell lines: a redox/polyamine-dependent effect. Carcinogenesis 2010 31 11 1982 1990 2-s2.0-78149248334 10.1093/carcin/bgq149
    • (2010) Carcinogenesis , vol.31 , Issue.11 , pp. 1982-1990
    • Huang, L.1    Zhu, C.2    Sun, Y.3    Xie, G.4    Mackenzie, G.G.5    Qiao, G.6    Komninou, D.7    Rigas, B.8
  • 21
    • 84255170384 scopus 로고    scopus 로고
    • Chemotherapeutic properties of phospho-nonsteroidal anti-inflammatory drugs, a new class of anticancer compounds
    • 2-s2.0-84255170384 10.1158/0008-5472.CAN-11-2349
    • Huang L., Mackenzie G. G., Sun Y., Ouyang N., Xie G., Vrankova K., Komninou D., Rigas B., Chemotherapeutic properties of phospho-nonsteroidal anti-inflammatory drugs, a new class of anticancer compounds. Cancer Research 2011 71 24 7617 7627 2-s2.0-84255170384 10.1158/0008-5472.CAN-11-2349
    • (2011) Cancer Research , vol.71 , Issue.24 , pp. 7617-7627
    • Huang, L.1    Mackenzie, G.G.2    Sun, Y.3    Ouyang, N.4    Xie, G.5    Vrankova, K.6    Komninou, D.7    Rigas, B.8
  • 22
    • 84857056141 scopus 로고    scopus 로고
    • Hydrogen sulfide-releasing NSAIDs inhibit the growth of human cancer cells: A general property and evidence of a tissue type-independent effect
    • 2-s2.0-84857056141 10.1016/j.bcp.2011.12.018
    • Chattopadhyay M., Kodela R., Nath N., Dastagirzada Y. M., Velázquez-Martínez C. A., Boring D., Kashfi K., Hydrogen sulfide-releasing NSAIDs inhibit the growth of human cancer cells: a general property and evidence of a tissue type-independent effect. Biochemical Pharmacology 2012 83 6 715 722 2-s2.0-84857056141 10.1016/j.bcp.2011.12.018
    • (2012) Biochemical Pharmacology , vol.83 , Issue.6 , pp. 715-722
    • Chattopadhyay, M.1    Kodela, R.2    Nath, N.3    Dastagirzada, Y.M.4    Velázquez- Martínez, C.A.5    Boring, D.6    Kashfi, K.7
  • 23
    • 84858182910 scopus 로고    scopus 로고
    • NOSH-aspirin: A novel nitric oxide-hydrogen sulfide-releasing hybrid: A new class of anti-inflammatory pharmaceuticals
    • 2-s2.0-84858182910 10.1021/ml300002m
    • Kodela R., Chattopadhyay M., Kashfi K., NOSH-aspirin: a novel nitric oxide-hydrogen sulfide-releasing hybrid: a new class of anti-inflammatory pharmaceuticals. ACS Medicinal Chemistry Letters 2012 3 3 257 262 2-s2.0-84858182910 10.1021/ml300002m
    • (2012) ACS Medicinal Chemistry Letters , vol.3 , Issue.3 , pp. 257-262
    • Kodela, R.1    Chattopadhyay, M.2    Kashfi, K.3
  • 24
    • 84858289256 scopus 로고    scopus 로고
    • NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse model
    • 2-s2.0-84858289256 10.1016/j.bbrc.2012.02.051
    • Chattopadhyay M., Kodela R., Olson K. R., Kashfi K., NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse model. Biochemical and Biophysical Research Communications 2012 419 3 523 528 2-s2.0-84858289256 10.1016/j.bbrc.2012.02.051
    • (2012) Biochemical and Biophysical Research Communications , vol.419 , Issue.3 , pp. 523-528
    • Chattopadhyay, M.1    Kodela, R.2    Olson, K.R.3    Kashfi, K.4
  • 25
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • 2-s2.0-0037180757 10.1038/nature01322
    • Coussens L. M., Werb Z., Inflammation and cancer. Nature 2002 420 6917 860 867 2-s2.0-0037180757 10.1038/nature01322
    • (2002) Nature , vol.420 , Issue.6917 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 26
    • 0027183769 scopus 로고
    • Inhibitory effect of aspirin on azoxymethane-induced colon carcinogenesis in F344 rats
    • 2-s2.0-0027183769
    • Reddy B. S., Rao C. V., Rivenson A., Kelloff G., Inhibitory effect of aspirin on azoxymethane-induced colon carcinogenesis in F344 rats. Carcinogenesis 1993 14 8 1493 1497 2-s2.0-0027183769
    • (1993) Carcinogenesis , vol.14 , Issue.8 , pp. 1493-1497
    • Reddy, B.S.1    Rao, C.V.2    Rivenson, A.3    Kelloff, G.4
  • 27
    • 0031911922 scopus 로고    scopus 로고
    • Effect of aspirin on induction of apoptosis in HT-29 human colon adenocarcinoma cells
    • 2-s2.0-0031911922 10.1016/S0006-2952(97)00400-0
    • Qiao L., Hanif R., Sphicas E., Shiff S. J., Rigas B., Effect of aspirin on induction of apoptosis in HT-29 human colon adenocarcinoma cells. Biochemical Pharmacology 1998 55 1 53 64 2-s2.0-0031911922 10.1016/S0006-2952(97)00400-0
    • (1998) Biochemical Pharmacology , vol.55 , Issue.1 , pp. 53-64
    • Qiao, L.1    Hanif, R.2    Sphicas, E.3    Shiff, S.J.4    Rigas, B.5
  • 29
    • 11044230487 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs inhibit cellular proliferation and upregulate cyclooxygenase-2 protein expression in endometrial cancer cells
    • 2-s2.0-11044230487 10.1111/j.1349-7006.2004.tb02200.x
    • Gao J., Niwa K., Sun W., Takemura M., Lian Z., Onogi K., Seishima M., Mori H., Tamaya T., Non-steroidal anti-inflammatory drugs inhibit cellular proliferation and upregulate cyclooxygenase-2 protein expression in endometrial cancer cells. Cancer Science 2004 95 11 901 907 2-s2.0-11044230487 10.1111/j.1349-7006.2004.tb02200.x
    • (2004) Cancer Science , vol.95 , Issue.11 , pp. 901-907
    • Gao, J.1    Niwa, K.2    Sun, W.3    Takemura, M.4    Lian, Z.5    Onogi, K.6    Seishima, M.7    Mori, H.8    Tamaya, T.9
  • 32
    • 1642514550 scopus 로고    scopus 로고
    • Aspirin commits yeast cells to apoptosis depending on carbon source
    • 2-s2.0-1642514550
    • Balzan R., Sapienza K., Galea D. R., Vassallo N., Frey H., Bannister W. H., Aspirin commits yeast cells to apoptosis depending on carbon source. Microbiology 2004 150 1 109 115 2-s2.0-1642514550
    • (2004) Microbiology , vol.150 , Issue.1 , pp. 109-115
    • Balzan, R.1    Sapienza, K.2    Galea, D.R.3    Vassallo, N.4    Frey, H.5    Bannister, W.H.6
  • 33
    • 79952253994 scopus 로고    scopus 로고
    • Subunits Rip1p and Cox9p of the respiratory chain contribute to diclofenac-induced mitochondrial dysfunction
    • 2-s2.0-79952253994 10.1099/mic.0.044578-0
    • Van Leeuwen J. S., Orij R., Luttik M. A. H., Smits G. J., Vermeulen N. P. E., Vos J. C., Subunits Rip1p and Cox9p of the respiratory chain contribute to diclofenac-induced mitochondrial dysfunction. Microbiology 2011 157 3 685 694 2-s2.0-79952253994 10.1099/mic.0.044578-0
    • (2011) Microbiology , vol.157 , Issue.3 , pp. 685-694
    • Van Leeuwen, J.S.1    Orij, R.2    Luttik, M.A.H.3    Smits, G.J.4    Vermeulen, N.P.E.5    Vos, J.C.6
  • 34
    • 0032878530 scopus 로고    scopus 로고
    • Aspirin induces cell death and caspase-dependent phosphatidylserine externalization in HT-29 human colon adenocarcinoma cells
    • 2-s2.0-0032878530 10.1038/sj.bjc.6690690
    • Castaño E., Dalmau M., Barragán M., Pueyo G., Bartrons R., Gil J., Aspirin induces cell death and caspase-dependent phosphatidylserine externalization in HT-29 human colon adenocarcinoma cells. British Journal of Cancer 1999 81 2 294 299 2-s2.0-0032878530 10.1038/sj.bjc.6690690
    • (1999) British Journal of Cancer , vol.81 , Issue.2 , pp. 294-299
    • Castaño, E.1    Dalmau, M.2    Barragán, M.3    Pueyo, G.4    Bartrons, R.5    Gil, J.6
  • 35
    • 0035740372 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs stimulate spermidine/spermine acetyltransferase and deplete polyamine content in colon cancer cells
    • 2-s2.0-0035740372 10.1046/j.1365-2362.2001.00901.x
    • Turchanowa L., Dauletbaev N., Milovic V., Stein J., Nonsteroidal anti-inflammatory drugs stimulate spermidine/spermine acetyltransferase and deplete polyamine content in colon cancer cells. European Journal of Clinical Investigation 2001 31 10 887 893 2-s2.0-0035740372 10.1046/j.1365-2362.2001. 00901.x
    • (2001) European Journal of Clinical Investigation , vol.31 , Issue.10 , pp. 887-893
    • Turchanowa, L.1    Dauletbaev, N.2    Milovic, V.3    Stein, J.4
  • 36
    • 0035348486 scopus 로고    scopus 로고
    • Aspirin-induced activation of the NF-kappaB signaling pathway: A novel mechanism for aspirin-mediated apoptosis in colon cancer cells
    • 2-s2.0-0035348486
    • Stark L. A., Din F. V., Zwacka R. M., Dunlop M. G., Aspirin-induced activation of the NF-kappaB signaling pathway: a novel mechanism for aspirin-mediated apoptosis in colon cancer cells. The FASEB Journal 2001 15 7 1273 1275 2-s2.0-0035348486
    • (2001) The FASEB Journal , vol.15 , Issue.7 , pp. 1273-1275
    • Stark, L.A.1    Din, F.V.2    Zwacka, R.M.3    Dunlop, M.G.4
  • 37
    • 0032529499 scopus 로고    scopus 로고
    • Aspirin and salicylate induce apoptosis and activation of caspases in B-cell chronic lymphocytic leukemia cells
    • 2-s2.0-0032529499
    • Bellosillo B., Piqué M., Barragán M., Castaño E., Villamor N., Colomer D., Montserrat E., Pons G., Gil J., Aspirin and salicylate induce apoptosis and activation of caspases in B-cell chronic lymphocytic leukemia cells. Blood 1998 92 4 1406 1414 2-s2.0-0032529499
    • (1998) Blood , vol.92 , Issue.4 , pp. 1406-1414
    • Bellosillo, B.1    Piqué, M.2    Barragán, M.3    Castaño, E.4    Villamor, N.5    Colomer, D.6    Montserrat, E.7    Pons, G.8    Gil, J.9
  • 38
    • 0034284923 scopus 로고    scopus 로고
    • Aspirin induces apoptosis through mitochondrial cytochrome c release
    • 2-s2.0-0034284923 10.1016/S0014-5793(00)01922-0
    • Piqué M., Barragán M., Dalmau M., Bellosillo B., Pons G., Gil J., Aspirin induces apoptosis through mitochondrial cytochrome c release. FEBS Letters 2000 480 2-3 193 196 2-s2.0-0034284923 10.1016/S0014-5793(00)01922- 0
    • (2000) FEBS Letters , vol.480 , Issue.2-3 , pp. 193-196
    • Piqué, M.1    Barragán, M.2    Dalmau, M.3    Bellosillo, B.4    Pons, G.5    Gil, J.6
  • 39
    • 0034487768 scopus 로고    scopus 로고
    • Aspirin induces apoptosis through release of cytochrome c from mitochondria
    • 2-s2.0-0034487768
    • Zimmermann K. C., Waterhouse N. J., Goldstein J. C., Schuler M., Green D. R., Aspirin induces apoptosis through release of cytochrome c from mitochondria. Neoplasia 2000 2 6 505 513 2-s2.0-0034487768
    • (2000) Neoplasia , vol.2 , Issue.6 , pp. 505-513
    • Zimmermann, K.C.1    Waterhouse, N.J.2    Goldstein, J.C.3    Schuler, M.4    Green, D.R.5
  • 40
    • 84864083713 scopus 로고    scopus 로고
    • Aspirin enhances TRAIL-induced apoptosis via regulation of ERK1/2 activation in human cervical cancer cells
    • Im R., Jang Y. J., Aspirin enhances TRAIL-induced apoptosis via regulation of ERK1/2 activation in human cervical cancer cells. Biochemical and Biophysical Research Communications 2012 424 65 70
    • (2012) Biochemical and Biophysical Research Communications , vol.424 , pp. 65-70
    • Im, R.1    Jang, Y.J.2
  • 41
    • 4644240763 scopus 로고    scopus 로고
    • Aspirin-induced mucosal cell death in human gastric cells: Evidence supporting an apoptotic mechanism
    • 2-s2.0-4644240763 10.1023/B:DDAS.0000042258.41480.30
    • Power J. J., Dennis M. S., Redlak M. J., Miller T. A., Aspirin-induced mucosal cell death in human gastric cells: evidence supporting an apoptotic mechanism. Digestive Diseases and Sciences 2004 49 9 1518 1525 2-s2.0-4644240763 10.1023/B:DDAS.0000042258.41480.30
    • (2004) Digestive Diseases and Sciences , vol.49 , Issue.9 , pp. 1518-1525
    • Power, J.J.1    Dennis, M.S.2    Redlak, M.J.3    Miller, T.A.4
  • 43
    • 25444453189 scopus 로고    scopus 로고
    • Role of mitochondria in aspirin-induced apoptosis in human gastric epithelial cells
    • 2-s2.0-25444453189 10.1152/ajpgi.00150.2005
    • Redlak M. J., Power J. J., Miller T. A., Role of mitochondria in aspirin-induced apoptosis in human gastric epithelial cells. American Journal of Physiology 2005 289 4 G731 G738 2-s2.0-25444453189 10.1152/ajpgi.00150.2005
    • (2005) American Journal of Physiology , vol.289 , Issue.4
    • Redlak, M.J.1    Power, J.J.2    Miller, T.A.3
  • 44
    • 0034806996 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs induce apoptosis in gastric cancer cells through up-regulation of bax and bak
    • 2-s2.0-0034806996
    • Zhou X. M., Wong B. C. Y., Fan X. M., Zhang H. B., Lin M. C. M., Kung H. F., Fan D. M., Lam S. K., Non-steroidal anti-inflammatory drugs induce apoptosis in gastric cancer cells through up-regulation of bax and bak. Carcinogenesis 2001 22 9 1393 1397 2-s2.0-0034806996
    • (2001) Carcinogenesis , vol.22 , Issue.9 , pp. 1393-1397
    • Zhou, X.M.1    Wong, B.C.Y.2    Fan, X.M.3    Zhang, H.B.4    Lin, M.C.M.5    Kung, H.F.6    Fan, D.M.7    Lam, S.K.8
  • 45
    • 80052043989 scopus 로고    scopus 로고
    • Acetylsalicylic acid-induced oxidative stress, cell cycle arrest, apoptosis and mitochondrial dysfunction in human hepatoma HepG2 cells
    • 2-s2.0-80052043989 10.1016/j.ejphar.2011.06.016
    • Raza H., John A., Benedict S., Acetylsalicylic acid-induced oxidative stress, cell cycle arrest, apoptosis and mitochondrial dysfunction in human hepatoma HepG2 cells. European Journal of Pharmacology 2011 668 1-2 15 24 2-s2.0-80052043989 10.1016/j.ejphar.2011.06.016
    • (2011) European Journal of Pharmacology , vol.668 , Issue.1-2 , pp. 15-24
    • Raza, H.1    John, A.2    Benedict, S.3
  • 46
    • 84863337989 scopus 로고    scopus 로고
    • Aspirin induces apoptosis in vitro and inhibits tumor growth of human hepatocellular carcinoma cells in a nude mouse xenograft model
    • 2-s2.0-84858627843 10.3892/ijo.2011.1304
    • Hossain M. A., Kim D. H., Jang J. Y., Kang Y. J., Yoon J.-H., Moon J.-O., Chung H. Y., Kim G.-Y., Choi Y. H., Copple B. L., Kim N. D., Aspirin induces apoptosis in vitro and inhibits tumor growth of human hepatocellular carcinoma cells in a nude mouse xenograft model. International Journal of Oncology 2012 40 4 1298 1304 2-s2.0-84858627843 10.3892/ijo.2011.1304
    • (2012) International Journal of Oncology , vol.40 , Issue.4 , pp. 1298-1304
    • Hossain, M.A.1    Kim, D.H.2    Jang, J.Y.3    Kang, Y.J.4    Yoon, J.-H.5    Moon, J.-O.6    Chung, H.Y.7    Kim, G.-Y.8    Choi, Y.H.9    Copple, B.L.10    Kim, N.D.11
  • 47
    • 33749404802 scopus 로고    scopus 로고
    • Aspirin induces apoptosis through the inhibition of proteasome function
    • 2-s2.0-33749404802 10.1074/jbc.M602629200
    • Dikshit P., Chatterjee M., Goswami A., Mishra A., Jana N. R., Aspirin induces apoptosis through the inhibition of proteasome function. Journal of Biological Chemistry 2006 281 39 29228 29235 2-s2.0-33749404802 10.1074/jbc.M602629200
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.39 , pp. 29228-29235
    • Dikshit, P.1    Chatterjee, M.2    Goswami, A.3    Mishra, A.4    Jana, N.R.5
  • 48
    • 0035884187 scopus 로고    scopus 로고
    • Sulindac sulfide-induced apoptosis involves death receptor 5 and the caspase 8-dependent pathway in human colon and prostate cancer cells
    • 2-s2.0-0035884187
    • Huang Y., He Q., Hillman M. J., Rong R., Sheikh M. S., Sulindac sulfide-induced apoptosis involves death receptor 5 and the caspase 8-dependent pathway in human colon and prostate cancer cells. Cancer Research 2001 61 18 6918 6924 2-s2.0-0035884187
    • (2001) Cancer Research , vol.61 , Issue.18 , pp. 6918-6924
    • Huang, Y.1    He, Q.2    Hillman, M.J.3    Rong, R.4    Sheikh, M.S.5
  • 49
    • 0346850853 scopus 로고    scopus 로고
    • Cyclooxygenase-independent induction of apoptosis by sulindac sulfone is mediated by polyamines in colon cancer
    • 2-s2.0-0346850853 10.1074/jbc.M307265200
    • Babbar N., Ignatenko N. A., Casero R. A. Jr., Gerner E. W., Cyclooxygenase-independent induction of apoptosis by sulindac sulfone is mediated by polyamines in colon cancer. Journal of Biological Chemistry 2003 278 48 47762 47775 2-s2.0-0346850853 10.1074/jbc.M307265200
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.48 , pp. 47762-47775
    • Babbar, N.1    Ignatenko, N.A.2    Casero, Jr.R.A.3    Gerner, E.W.4
  • 51
    • 78650840096 scopus 로고    scopus 로고
    • Ibuprofen inhibits activation of nuclear β -catenin in human colon adenomas and induces the phosphorylation of GSK-3 β
    • 2-s2.0-78650840096 10.1158/1940-6207.CAPR-10-0021
    • Greenspan E. J., Madigan J. P., Boardman L. A., Rosenberg D. W., Ibuprofen inhibits activation of nuclear β -catenin in human colon adenomas and induces the phosphorylation of GSK-3 β Cancer Prevention Research 2011 4 1 161 171 2-s2.0-78650840096 10.1158/1940-6207.CAPR-10-0021
    • (2011) Cancer Prevention Research , vol.4 , Issue.1 , pp. 161-171
    • Greenspan, E.J.1    Madigan, J.P.2    Boardman, L.A.3    Rosenberg, D.W.4
  • 52
    • 84867064767 scopus 로고    scopus 로고
    • Small molecule tolfenamic acid inhibits PC-3 cell proliferation and invasion in vitro, and tumor growth in orthotopic mouse model for prostate cancer
    • 2-s2.0-84859151159 10.1002/pros.22518
    • Sankpal U. T., Abdelrahim M., Connelly S. F., Lee C. M., Madero-Visbal R., Colon J., Smith J., Safe S., Maliakal P., Basha R., Small molecule tolfenamic acid inhibits PC-3 cell proliferation and invasion in vitro, and tumor growth in orthotopic mouse model for prostate cancer. Prostate 2012 72 1648 1658 2-s2.0-84859151159 10.1002/pros.22518
    • (2012) Prostate , vol.72 , pp. 1648-1658
    • Sankpal, U.T.1    Abdelrahim, M.2    Connelly, S.F.3    Lee, C.M.4    Madero-Visbal, R.5    Colon, J.6    Smith, J.7    Safe, S.8    Maliakal, P.9    Basha, R.10
  • 53
    • 57349145254 scopus 로고    scopus 로고
    • Nitric oxide-donating aspirin inhibits the growth of pancreatic cancer cells through redox-dependent signaling
    • 2-s2.0-57349145254 10.1016/j.canlet.2008.08.006
    • Zhou H., Huang L., Sun Y., Rigas B., Nitric oxide-donating aspirin inhibits the growth of pancreatic cancer cells through redox-dependent signaling. Cancer Letters 2009 273 2 292 299 2-s2.0-57349145254 10.1016/j.canlet.2008.08.006
    • (2009) Cancer Letters , vol.273 , Issue.2 , pp. 292-299
    • Zhou, H.1    Huang, L.2    Sun, Y.3    Rigas, B.4
  • 54
    • 0345275877 scopus 로고    scopus 로고
    • Growth inhibition of human colon cancer cells by nitric oxide (NO)-donating aspirin is associated with cyclooxygenase-2 induction and beta-catenin/T-cell factor signaling, nuclear factor-kappaB, and NO synthase 2 inhibition: Implications for chemoprevention
    • 2-s2.0-0345275877
    • Williams J. L., Nath N., Chen J., Hundley T. R., Gao J., Kopelovich L., Kashfi K., Rigas B., Growth inhibition of human colon cancer cells by nitric oxide (NO)-donating aspirin is associated with cyclooxygenase-2 induction and beta-catenin/T-cell factor signaling, nuclear factor-kappaB, and NO synthase 2 inhibition: Implications for chemoprevention. Cancer Research 2003 63 22 7613 7618 2-s2.0-0345275877
    • (2003) Cancer Research , vol.63 , Issue.22 , pp. 7613-7618
    • Williams, J.L.1    Nath, N.2    Chen, J.3    Hundley, T.R.4    Gao, J.5    Kopelovich, L.6    Kashfi, K.7    Rigas, B.8
  • 55
    • 40549088542 scopus 로고    scopus 로고
    • NO-donating aspirin inhibits the activation of NF- B in human cancer cell lines and Min mice
    • 2-s2.0-40549088542 10.1093/carcin/bgm275
    • Williams J. I., Ji P., Ouyang N., Liu X., Rigas B., NO-donating aspirin inhibits the activation of NF- B in human cancer cell lines and Min mice. Carcinogenesis 2008 29 2 390 397 2-s2.0-40549088542 10.1093/carcin/bgm275
    • (2008) Carcinogenesis , vol.29 , Issue.2 , pp. 390-397
    • Williams, J.I.1    Ji, P.2    Ouyang, N.3    Liu, X.4    Rigas, B.5
  • 56
    • 54249105017 scopus 로고    scopus 로고
    • The thioredoxin system mediates redox-induced cell death in human colon cancer cells: Implications for the mechanism of action of anticancer agents
    • 2-s2.0-54249105017 10.1158/0008-5472.CAN-08-2010
    • Sun Y., Rigas B., The thioredoxin system mediates redox-induced cell death in human colon cancer cells: implications for the mechanism of action of anticancer agents. Cancer Research 2008 68 20 8269 8277 2-s2.0-54249105017 10.1158/0008-5472.CAN-08-2010
    • (2008) Cancer Research , vol.68 , Issue.20 , pp. 8269-8277
    • Sun, Y.1    Rigas, B.2
  • 57
    • 77957938071 scopus 로고    scopus 로고
    • NO-releasing NSAIDs suppress NF- B signaling in vitro and in vivo through S-nitrosylation
    • 2-s2.0-77957938071 10.1016/j.canlet.2010.07.006
    • Chattopadhyay M., Goswami S., Rodes D. B., Kodela R., Velazquez C. A., Boring D., Crowell J. A., Kashfi K., NO-releasing NSAIDs suppress NF- B signaling in vitro and in vivo through S-nitrosylation. Cancer Letters 2010 298 2 204 211 2-s2.0-77957938071 10.1016/j.canlet.2010.07.006
    • (2010) Cancer Letters , vol.298 , Issue.2 , pp. 204-211
    • Chattopadhyay, M.1    Goswami, S.2    Rodes, D.B.3    Kodela, R.4    Velazquez, C.A.5    Boring, D.6    Crowell, J.A.7    Kashfi, K.8
  • 58
    • 28044436484 scopus 로고    scopus 로고
    • Nitric oxide-donating aspirin induces apoptosis in human colon cancer cells through induction of oxidative stress
    • 2-s2.0-28044436484 10.1073/pnas.0506893102
    • Gao J., Liu X., Rigas B., Nitric oxide-donating aspirin induces apoptosis in human colon cancer cells through induction of oxidative stress. Proceedings of the National Academy of Sciences of the United States of America 2005 102 47 17207 17212 2-s2.0-28044436484 10.1073/pnas.0506893102
    • (2005) Proceedings of the National Academy of Sciences of the United States of America , vol.102 , Issue.47 , pp. 17207-17212
    • Gao, J.1    Liu, X.2    Rigas, B.3
  • 60
    • 84857060149 scopus 로고    scopus 로고
    • Hydrogen sulfide-releasing aspirin suppresses NF- B signaling in estrogen receptor negative breast cancer cells in vitro and in vivo
    • 2-s2.0-84857060149 10.1016/j.bcp.2011.12.019
    • Chattopadhyay M., Kodela R., Nath N., Barsegian A., Boring D., Kashfi K., Hydrogen sulfide-releasing aspirin suppresses NF- B signaling in estrogen receptor negative breast cancer cells in vitro and in vivo. Biochemical Pharmacology 2012 83 6 723 732 2-s2.0-84857060149 10.1016/j.bcp.2011.12.019
    • (2012) Biochemical Pharmacology , vol.83 , Issue.6 , pp. 723-732
    • Chattopadhyay, M.1    Kodela, R.2    Nath, N.3    Barsegian, A.4    Boring, D.5    Kashfi, K.6
  • 61
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
    • 2-s2.0-0015237292
    • Vane J. R., Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature: New biology 1971 231 25 232 235 2-s2.0-0015237292
    • (1971) Nature: New Biology , vol.231 , Issue.25 , pp. 232-235
    • Vane, J.R.1
  • 63
    • 0033971808 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is related to prostaglandin biosynthesis and angiogenesis in human gastric cancer
    • 2-s2.0-0033971808
    • Uefuji K., Ichikura T., Mochizuki H., Cyclooxygenase-2 expression is related to prostaglandin biosynthesis and angiogenesis in human gastric cancer. Clinical Cancer Research 2000 6 1 135 138 2-s2.0-0033971808
    • (2000) Clinical Cancer Research , vol.6 , Issue.1 , pp. 135-138
    • Uefuji, K.1    Ichikura, T.2    Mochizuki, H.3
  • 64
    • 82155187174 scopus 로고    scopus 로고
    • Effects of cyclooxygenase-2 on human esophageal squamous cell carcinoma
    • 2-s2.0-82155187174 10.3748/wjg.v17.i41.4572
    • Zhang L., Wu Y.-D., Li P., Tu J., Niu Y.-L., Xu C.-M., Zhang S.-T., Effects of cyclooxygenase-2 on human esophageal squamous cell carcinoma. World Journal of Gastroenterology 2011 17 41 4572 4580 2-s2.0-82155187174 10.3748/wjg.v17.i41.4572
    • (2011) World Journal of Gastroenterology , vol.17 , Issue.41 , pp. 4572-4580
    • Zhang, L.1    Wu, Y.-D.2    Li, P.3    Tu, J.4    Niu, Y.-L.5    Xu, C.-M.6    Zhang, S.-T.7
  • 65
    • 0027993458 scopus 로고
    • Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
    • 2-s2.0-0027993458
    • Eberhart C. E., Coffey R. J., Radhika A., Giardiello F. M., Ferrenbach S., Dubois R. N., Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 1994 107 4 1183 1188 2-s2.0-0027993458
    • (1994) Gastroenterology , vol.107 , Issue.4 , pp. 1183-1188
    • Eberhart, C.E.1    Coffey, R.J.2    Radhika, A.3    Giardiello, F.M.4    Ferrenbach, S.5    Dubois, R.N.6
  • 68
    • 0030000645 scopus 로고    scopus 로고
    • Prostaglandins, their inhibitors and cancer
    • 2-s2.0-0030000645 10.1016/S0952-3278(96)90064-2
    • Lupulescu A., Prostaglandins, their inhibitors and cancer. Prostaglandins Leukotrienes and Essential Fatty Acids 1996 54 2 83 94 2-s2.0-0030000645 10.1016/S0952-3278(96)90064-2
    • (1996) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.54 , Issue.2 , pp. 83-94
    • Lupulescu, A.1
  • 69
    • 0030894288 scopus 로고    scopus 로고
    • Prostaglandin H synthases, nonsteroidal anti-inflammatory drugs, and colon cancer
    • 2-s2.0-0030894288
    • Levy G. N., Prostaglandin H synthases, nonsteroidal anti-inflammatory drugs, and colon cancer. FASEB Journal 1997 11 4 234 247 2-s2.0-0030894288
    • (1997) FASEB Journal , vol.11 , Issue.4 , pp. 234-247
    • Levy, G.N.1
  • 70
    • 0030813607 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and colorectal cancer: Evolving concepts of their chemopreventive actions
    • 2-s2.0-0030813607
    • Shiff S. J., Rigas B., Nonsteroidal anti-inflammatory drugs and colorectal cancer: evolving concepts of their chemopreventive actions. Gastroenterology 1997 113 6 1992 1998 2-s2.0-0030813607
    • (1997) Gastroenterology , vol.113 , Issue.6 , pp. 1992-1998
    • Shiff, S.J.1    Rigas, B.2
  • 71
    • 29244449354 scopus 로고    scopus 로고
    • Prostaglandins and cancer
    • 2-s2.0-29244449354 10.1136/gut.2004.047100
    • Wang D., Dubois R. N., Prostaglandins and cancer. Gut 2006 55 1 115 122 2-s2.0-29244449354 10.1136/gut.2004.047100
    • (2006) Gut , vol.55 , Issue.1 , pp. 115-122
    • Wang, D.1    Dubois, R.N.2
  • 72
    • 0030606299 scopus 로고    scopus 로고
    • Suppression of intestinal polyposis in Apc(Δ716) knockout mice by inhibition of cyclooxygenase 2 (COX-2)
    • 2-s2.0-0030606299 10.1016/S0092-8674(00)81988-1
    • Oshima M., Dinchuk J. E., Kargman S. L., Oshima H., Hancock B., Kwong E., Trzaskos J. M., Evans J. F., Taketo M. M., Suppression of intestinal polyposis in Apc(Δ716) knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell 1996 87 5 803 809 2-s2.0-0030606299 10.1016/S0092-8674(00)81988-1
    • (1996) Cell , vol.87 , Issue.5 , pp. 803-809
    • Oshima, M.1    Dinchuk, J.E.2    Kargman, S.L.3    Oshima, H.4    Hancock, B.5    Kwong, E.6    Trzaskos, J.M.7    Evans, J.F.8    Taketo, M.M.9
  • 74
    • 0029794742 scopus 로고    scopus 로고
    • Evaluation of cyclooxygenase-2 inhibitor for potential chemopreventive properties in colon carcinogenesis
    • 2-s2.0-0029794742
    • Reddy B. S., Rao C. V., Seibert K., Evaluation of cyclooxygenase-2 inhibitor for potential chemopreventive properties in colon carcinogenesis. Cancer Research 1996 56 20 4566 4569 2-s2.0-0029794742
    • (1996) Cancer Research , vol.56 , Issue.20 , pp. 4566-4569
    • Reddy, B.S.1    Rao, C.V.2    Seibert, K.3
  • 77
    • 33744479992 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs in prevention gastric cancer
    • 2-s2.0-33744479992
    • Dai Y., Wang W.-H., Non-steroidal anti-inflammatory drugs in prevention gastric cancer. World Journal of Gastroenterology 2006 12 19 2884 2889 2-s2.0-33744479992
    • (2006) World Journal of Gastroenterology , vol.12 , Issue.19 , pp. 2884-2889
    • Dai, Y.1    Wang, W.-H.2
  • 78
    • 43049168293 scopus 로고    scopus 로고
    • NSAIDs and apoptosis
    • 2-s2.0-43049168293 10.1007/s00018-008-7511-x
    • Jana N. R., NSAIDs and apoptosis. Cellular and Molecular Life Sciences 2008 65 9 1295 1301 2-s2.0-43049168293 10.1007/s00018-008-7511-x
    • (2008) Cellular and Molecular Life Sciences , vol.65 , Issue.9 , pp. 1295-1301
    • Jana, N.R.1
  • 80
    • 0030758925 scopus 로고    scopus 로고
    • Sulindac causes rapid regression of preexisting tumors in Min/+ mice independent of prostaglandin biosynthesis
    • 2-s2.0-0030758925
    • Chiu C.-H., McEntee M. F., Whelan J., Sulindac causes rapid regression of preexisting tumors in Min/+ mice independent of prostaglandin biosynthesis. Cancer Research 1997 57 19 4267 4273 2-s2.0-0030758925
    • (1997) Cancer Research , vol.57 , Issue.19 , pp. 4267-4273
    • Chiu, C.-H.1    McEntee, M.F.2    Whelan, J.3
  • 81
    • 0030602860 scopus 로고    scopus 로고
    • Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway
    • 2-s2.0-0030602860 10.1016/0006-2952(96)00181-5
    • Hanif R., Pittas A., Feng Y., Koutsos M. I., Qiao L., Staiano-Coico L., Shiff S. I., Rigas B., Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway. Biochemical Pharmacology 1996 52 2 237 245 2-s2.0-0030602860 10.1016/0006-2952(96)00181-5
    • (1996) Biochemical Pharmacology , vol.52 , Issue.2 , pp. 237-245
    • Hanif, R.1    Pittas, A.2    Feng, Y.3    Koutsos, M.I.4    Qiao, L.5    Staiano-Coico, L.6    Shiff, S.I.7    Rigas, B.8
  • 82
    • 0030448021 scopus 로고    scopus 로고
    • Functions of ceramide in coordinating cellular responses to stress
    • 2-s2.0-0030448021 10.1126/science.274.5294.1855
    • Hannun Y. A., Functions of ceramide in coordinating cellular responses to stress. Science 1996 274 5294 1855 1859 2-s2.0-0030448021 10.1126/science.274. 5294.1855
    • (1996) Science , vol.274 , Issue.5294 , pp. 1855-1859
    • Hannun, Y.A.1
  • 84
    • 0035853767 scopus 로고    scopus 로고
    • Arachidonic acid causes cell death through the mitochondrial permeability transition. Implications for tumor necrosis factor- α; apoptotic signaling
    • 2-s2.0-0035853767 10.1074/jbc.M010603200
    • Scorrano L., Penzo D., Petronilli V., Pagano F., Bernardi P., Arachidonic acid causes cell death through the mitochondrial permeability transition. Implications for tumor necrosis factor- α; apoptotic signaling. Journal of Biological Chemistry 2001 276 15 12035 12040 2-s2.0-0035853767 10.1074/jbc.M010603200
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.15 , pp. 12035-12040
    • Scorrano, L.1    Penzo, D.2    Petronilli, V.3    Pagano, F.4    Bernardi, P.5
  • 85
    • 0033575760 scopus 로고    scopus 로고
    • Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts
    • 2-s2.0-0033575760 10.1084/jem.190.4.451
    • Zhang X., Morham S. G., Langenbach R., Young D. A., Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts. Journal of Experimental Medicine 1999 190 4 451 459 2-s2.0-0033575760 10.1084/jem.190.4.451
    • (1999) Journal of Experimental Medicine , vol.190 , Issue.4 , pp. 451-459
    • Zhang, X.1    Morham, S.G.2    Langenbach, R.3    Young, D.A.4
  • 86
    • 0030879456 scopus 로고    scopus 로고
    • Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: Independence from COX-2 protein expression
    • 2-s2.0-0030879456
    • Elder D. J. E., Halton D. E., Hague A., Paraskeva C., Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: independence from COX-2 protein expression. Clinical Cancer Research 1997 3 10 1679 1683 2-s2.0-0030879456
    • (1997) Clinical Cancer Research , vol.3 , Issue.10 , pp. 1679-1683
    • Elder, D.J.E.1    Halton, D.E.2    Hague, A.3    Paraskeva, C.4
  • 89
    • 0029974533 scopus 로고    scopus 로고
    • Inhibition of colon cancer precursors in the rat by sulindac sulphone is not dependent on inhibition of prostaglandin synthesis
    • 2-s2.0-0029974533
    • Charalambous D., O'Brien P. E., Inhibition of colon cancer precursors in the rat by sulindac sulphone is not dependent on inhibition of prostaglandin synthesis. Journal of Gastroenterology and Hepatology 1996 11 4 307 310 2-s2.0-0029974533
    • (1996) Journal of Gastroenterology and Hepatology , vol.11 , Issue.4 , pp. 307-310
    • Charalambous, D.1    O'Brien, P.E.2
  • 91
    • 0036912306 scopus 로고    scopus 로고
    • Aspirin and sodium salicylate inhibit proliferation and induce apoptosis in rheumatoid synovial cells
    • 2-s2.0-0036912306 10.1211/002235702261
    • Yamazaki R., Kusunoki N., Matsuzaki T., Hashimoto S., Kawai S., Aspirin and sodium salicylate inhibit proliferation and induce apoptosis in rheumatoid synovial cells. Journal of Pharmacy and Pharmacology 2002 54 12 1675 1679 2-s2.0-0036912306 10.1211/002235702261
    • (2002) Journal of Pharmacy and Pharmacology , vol.54 , Issue.12 , pp. 1675-1679
    • Yamazaki, R.1    Kusunoki, N.2    Matsuzaki, T.3    Hashimoto, S.4    Kawai, S.5
  • 92
    • 0033575255 scopus 로고    scopus 로고
    • Suicidal tendencies: Apoptotic cell death by caspase family proteinases
    • 2-s2.0-0033575255 10.1074/jbc.274.29.20049
    • Wolf B. B., Green D. R., Suicidal tendencies: apoptotic cell death by caspase family proteinases. Journal of Biological Chemistry 1999 274 29 20049 20052 2-s2.0-0033575255 10.1074/jbc.274.29.20049
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.29 , pp. 20049-20052
    • Wolf, B.B.1    Green, D.R.2
  • 93
    • 53449089446 scopus 로고    scopus 로고
    • Mitochondrial involvement in aspirin-induced apoptosis in yeast
    • 2-s2.0-53449089446 10.1099/mic.0.2008/017228-0
    • Sapienza K., Bannister W., Balzan R., Mitochondrial involvement in aspirin-induced apoptosis in yeast. Microbiology 2008 154 9 2740 2747 2-s2.0-53449089446 10.1099/mic.0.2008/017228-0
    • (2008) Microbiology , vol.154 , Issue.9 , pp. 2740-2747
    • Sapienza, K.1    Bannister, W.2    Balzan, R.3
  • 94
    • 0032555697 scopus 로고    scopus 로고
    • Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
    • 2-s2.0-0032555697
    • Li H., Zhu H., Xu C.-J., Yuan J., Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998 94 4 491 501 2-s2.0-0032555697
    • (1998) Cell , vol.94 , Issue.4 , pp. 491-501
    • Li, H.1    Zhu, H.2    Xu, C.-J.3    Yuan, J.4
  • 95
    • 0033647484 scopus 로고    scopus 로고
    • Caspase-8 in apoptosis: The beginning of "the end"?
    • 2-s2.0-0033647484
    • Kruidering M., Evan G. I., Caspase-8 in apoptosis: the beginning of "the end"? IUBMB Life 2000 50 2 85 90 2-s2.0-0033647484
    • (2000) IUBMB Life , vol.50 , Issue.2 , pp. 85-90
    • Kruidering, M.1    Evan, G.I.2
  • 96
    • 0037115740 scopus 로고    scopus 로고
    • Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein
    • 2-s2.0-0037115740 10.1042/BJ20020972
    • Roucou X., Montessuit S., Antonsson B., Martinou J.-C., Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein. Biochemical Journal 2002 368 3 915 921 2-s2.0-0037115740 10.1042/BJ20020972
    • (2002) Biochemical Journal , vol.368 , Issue.3 , pp. 915-921
    • Roucou, X.1    Montessuit, S.2    Antonsson, B.3    Martinou, J.-C.4
  • 97
    • 9644282960 scopus 로고    scopus 로고
    • NO-donating aspirin inhibits the growth of leukemic Jurkat cells and modulates β -catenin expression
    • 2-s2.0-9644282960 10.1016/j.bbrc.2004.11.009
    • Nath N., Labaze G., Rigas B., Kashfi K., NO-donating aspirin inhibits the growth of leukemic Jurkat cells and modulates β -catenin expression. Biochemical and Biophysical Research Communications 2005 326 1 93 99 2-s2.0-9644282960 10.1016/j.bbrc.2004.11.009
    • (2005) Biochemical and Biophysical Research Communications , vol.326 , Issue.1 , pp. 93-99
    • Nath, N.1    Labaze, G.2    Rigas, B.3    Kashfi, K.4
  • 98
    • 55949136916 scopus 로고    scopus 로고
    • NSAIDs downregulate Bcl-XL and dissociate BAX and Bcl-X L to induce apoptosis in colon cancer cells
    • 2-s2.0-55949136916 10.1080/01635580802381261
    • Bank A., Yu J., Zhang L., NSAIDs downregulate Bcl-XL and dissociate BAX and Bcl-X L to induce apoptosis in colon cancer cells. Nutrition and Cancer 2008 60 1 98 103 2-s2.0-55949136916 10.1080/01635580802381261
    • (2008) Nutrition and Cancer , vol.60 , Issue.1 , pp. 98-103
    • Bank, A.1    Yu, J.2    Zhang, L.3
  • 99
    • 0031036081 scopus 로고    scopus 로고
    • Uncoupling effects of diclofenac and aspirin in the perfused liver and isolated hepatic mitochondria of rat
    • 2-s2.0-0031036081 10.1016/S0005-2728(96)00109-0
    • Petrescu I., Tarba C., Uncoupling effects of diclofenac and aspirin in the perfused liver and isolated hepatic mitochondria of rat. Biochimica et Biophysica Acta-Bioenergetics 1997 1318 3 385 394 2-s2.0-0031036081 10.1016/S0005-2728(96)00109-0
    • (1997) Biochimica et Biophysica Acta-Bioenergetics , vol.1318 , Issue.3 , pp. 385-394
    • Petrescu, I.1    Tarba, C.2
  • 100
    • 0031570791 scopus 로고    scopus 로고
    • Diclofenac sodium and mefenamic acid: Potent inducers of the membrane permeability transition in renal cortex mitochondria
    • 2-s2.0-0031570791 10.1006/abbi.1997.9985
    • Uyemura S. A., Santos A. C., Mingatto F. E., Jordani M. C., Curti C., Diclofenac sodium and mefenamic acid: potent inducers of the membrane permeability transition in renal cortex mitochondria. Archives of Biochemistry and Biophysics 1997 342 2 231 235 2-s2.0-0031570791 10.1006/abbi.1997.9985
    • (1997) Archives of Biochemistry and Biophysics , vol.342 , Issue.2 , pp. 231-235
    • Uyemura, S.A.1    Santos, A.C.2    Mingatto, F.E.3    Jordani, M.C.4    Curti, C.5
  • 101
    • 0037986693 scopus 로고    scopus 로고
    • Salicylate enhances necrosis and apoptosis mediated by the mitochondrial permeability transition
    • 2-s2.0-0037986693 10.1093/toxsci/kfg045
    • Oh K.-W., Qian T., Brenner D. A., Lemasters J. J., Salicylate enhances necrosis and apoptosis mediated by the mitochondrial permeability transition. Toxicological Sciences 2003 73 1 44 52 2-s2.0-0037986693 10.1093/toxsci/kfg045
    • (2003) Toxicological Sciences , vol.73 , Issue.1 , pp. 44-52
    • Oh, K.-W.1    Qian, T.2    Brenner, D.A.3    Lemasters, J.J.4
  • 102
    • 0023881236 scopus 로고
    • Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy
    • 2-s2.0-0023881236
    • Pegg A. E., Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy. Cancer Research 1988 48 4 759 774 2-s2.0-0023881236
    • (1988) Cancer Research , vol.48 , Issue.4 , pp. 759-774
    • Pegg, A.E.1
  • 103
    • 0014323475 scopus 로고
    • Amine synthesis in rapidly growing tissues: Ornithine decarboxylase activity in regenerating rat liver, chick embryo, and various tumors
    • 2-s2.0-0014323475
    • Russell D., Snyder S. H., Amine synthesis in rapidly growing tissues: ornithine decarboxylase activity in regenerating rat liver, chick embryo, and various tumors. Proceedings of the National Academy of Sciences of the United States of America 1968 60 4 1420 1427 2-s2.0-0014323475
    • (1968) Proceedings of the National Academy of Sciences of the United States of America , vol.60 , Issue.4 , pp. 1420-1427
    • Russell, D.1    Snyder, S.H.2
  • 104
    • 0029134770 scopus 로고
    • Development of difluoromethylornithine as a chemoprevention agent for the management of colon cancer
    • 2-s2.0-0029134770
    • Meyskens F. L. Jr., Gerner E. W., Development of difluoromethylornithine as a chemoprevention agent for the management of colon cancer. Journal of Cellular Biochemistry 1995 58 22 126 131 2-s2.0-0029134770
    • (1995) Journal of Cellular Biochemistry , vol.58 , Issue.22 , pp. 126-131
    • Meyskens, Jr.F.L.1    Gerner, E.W.2
  • 105
    • 0035865678 scopus 로고    scopus 로고
    • Manipulation of the expression of regulatory genes of polyamine metabolism results in specific alterations of the cell-cycle progression
    • 2-s2.0-0035865678 10.1042/0264-6021:3540217
    • Scorcioni F., Corti A., Davalli P., Astancolle S., Bettuzzi S., Manipulation of the expression of regulatory genes of polyamine metabolism results in specific alterations of the cell-cycle progression. Biochemical Journal 2001 354 1 217 223 2-s2.0-0035865678 10.1042/0264-6021:3540217
    • (2001) Biochemical Journal , vol.354 , Issue.1 , pp. 217-223
    • Scorcioni, F.1    Corti, A.2    Davalli, P.3    Astancolle, S.4    Bettuzzi, S.5
  • 106
    • 0035026932 scopus 로고    scopus 로고
    • NF- B activation and susceptibility to apoptosis after polyamine depletion in intestinal epithelial cells
    • 2-s2.0-0035026932
    • Li L., Rao J. N., Bass B. L., Wang J.-Y., NF- B activation and susceptibility to apoptosis after polyamine depletion in intestinal epithelial cells. American Journal of Physiology 2001 280 5 G992 G1004 2-s2.0-0035026932
    • (2001) American Journal of Physiology , vol.280 , Issue.5
    • Li, L.1    Rao, J.N.2    Bass, B.L.3    Wang, J.-Y.4
  • 107
    • 32944475762 scopus 로고    scopus 로고
    • Induction of spermidine/spermine N1-acetyltransferase (SSAT) by aspirin in Caco-2 colon cancer cells
    • 2-s2.0-32944475762 10.1042/BJ20051298
    • Babbar N., Gerner E. W., Casero R. A. Jr., Induction of spermidine/spermine N1-acetyltransferase (SSAT) by aspirin in Caco-2 colon cancer cells. Biochemical Journal 2006 394 1 317 324 2-s2.0-32944475762 10.1042/BJ20051298
    • (2006) Biochemical Journal , vol.394 , Issue.1 , pp. 317-324
    • Babbar, N.1    Gerner, E.W.2    Casero, Jr.R.A.3
  • 110
    • 79960103968 scopus 로고    scopus 로고
    • Phospho-sulindac (OXT-328) combined with difluoromethylornithine prevents colon cancer in mice
    • 2-s2.0-79960103968 10.1158/1940-6207.CAPR-11-0067
    • Mackenzie G. G., Ouyang N., Xie G., Vrankova K., Huang L., Sun Y., Komninou D., Kopelovich L., Rigas B., Phospho-sulindac (OXT-328) combined with difluoromethylornithine prevents colon cancer in mice. Cancer Prevention Research 2011 4 7 1052 1060 2-s2.0-79960103968 10.1158/1940-6207.CAPR-11-0067
    • (2011) Cancer Prevention Research , vol.4 , Issue.7 , pp. 1052-1060
    • Mackenzie, G.G.1    Ouyang, N.2    Xie, G.3    Vrankova, K.4    Huang, L.5    Sun, Y.6    Komninou, D.7    Kopelovich, L.8    Rigas, B.9
  • 111
    • 77957350899 scopus 로고    scopus 로고
    • Phospho-sulindac (OXT-328), a novel sulindac derivative, is safe and effective in colon cancer prevention in mice
    • 2-s2.0-77957350899 10.1053/j.gastro.2010.06.044
    • MacKenzie G. G., Sun Y., Huang L., Xie G., Ouyang N., Gupta R. C., Johnson F., Komninou D., Kopelovich L., Rigas B., Phospho-sulindac (OXT-328), a novel sulindac derivative, is safe and effective in colon cancer prevention in mice. Gastroenterology 2010 139 4 1320 1332 2-s2.0-77957350899 10.1053/j.gastro.2010.06.044
    • (2010) Gastroenterology , vol.139 , Issue.4 , pp. 1320-1332
    • Mackenzie, G.G.1    Sun, Y.2    Huang, L.3    Xie, G.4    Ouyang, N.5    Gupta, R.C.6    Johnson, F.7    Komninou, D.8    Kopelovich, L.9    Rigas, B.10
  • 112
    • 0030271387 scopus 로고    scopus 로고
    • Nf- B: Ten years after
    • 2-s2.0-0030271387 10.1016/S0092-8674(00)81318-5
    • Baeuerle P. A., Baltimore D., Nf- B: ten years after. Cell 1996 87 1 13 20 2-s2.0-0030271387 10.1016/S0092-8674(00)81318-5
    • (1996) Cell , vol.87 , Issue.1 , pp. 13-20
    • Baeuerle, P.A.1    Baltimore, D.2
  • 113
    • 0033600604 scopus 로고    scopus 로고
    • The beginning of the end: I B kinase (IKK) and NF- B activation
    • 2-s2.0-0033600604 10.1074/jbc.274.39.27339
    • Karin M., The beginning of the end: I B kinase (IKK) and NF- B activation. Journal of Biological Chemistry 1999 274 39 27339 27342 2-s2.0-0033600604 10.1074/jbc.274.39.27339
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.39 , pp. 27339-27342
    • Karin, M.1
  • 114
    • 0032487857 scopus 로고    scopus 로고
    • The anti-inflammatory agents aspirin and salicylate inhibit the activity of i B kinase- β
    • 2-s2.0-0032487857 10.1038/23948
    • Yin M.-J., Yamamoto Y., Gaynor R. B., The anti-inflammatory agents aspirin and salicylate inhibit the activity of I B kinase- β Nature 1998 396 6706 77 80 2-s2.0-0032487857 10.1038/23948
    • (1998) Nature , vol.396 , Issue.6706 , pp. 77-80
    • Yin, M.-J.1    Yamamoto, Y.2    Gaynor, R.B.3
  • 116
    • 33846006906 scopus 로고    scopus 로고
    • HER-2 and NF- B as the targets for therapy-resistant breast cancer
    • 2-s2.0-33846006906
    • Ahmed K. M., Cao N., Li J. J., HER-2 and NF- B as the targets for therapy-resistant breast cancer. Anticancer Research 2006 26 6 B 4235 4243 2-s2.0-33846006906
    • (2006) Anticancer Research , vol.26 , Issue.B6 , pp. 4235-4243
    • Ahmed, K.M.1    Cao, N.2    Li, J.J.3
  • 117
    • 84865662406 scopus 로고    scopus 로고
    • Downregulation of NF-kappaB and PCNA in the regulatory pathways of apoptosis by cyclooxygenase-2 inhibitors in experimental lung cancer
    • Setia S., Sanyal S. N., Downregulation of NF-kappaB and PCNA in the regulatory pathways of apoptosis by cyclooxygenase-2 inhibitors in experimental lung cancer. Molecular and Cellular Biochemistry 2012 369 75 86
    • (2012) Molecular and Cellular Biochemistry , vol.369 , pp. 75-86
    • Setia, S.1    Sanyal, S.N.2
  • 118
    • 33845344739 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs to potentiate chemotherapy effects: From lab to clinic
    • 2-s2.0-33845344739 10.1016/j.critrevonc.2006.07.001
    • de Groot D. J. A., de Vries E. G. E., Groen H. J. M., de Jong S., Non-steroidal anti-inflammatory drugs to potentiate chemotherapy effects: from lab to clinic. Critical Reviews in Oncology/Hematology 2007 61 1 52 69 2-s2.0-33845344739 10.1016/j.critrevonc.2006.07.001
    • (2007) Critical Reviews in Oncology/Hematology , vol.61 , Issue.1 , pp. 52-69
    • De Groot, D.J.A.1    De Vries, E.G.E.2    Groen, H.J.M.3    De Jong, S.4
  • 119
    • 0028167846 scopus 로고
    • Inhibition of NF- B by sodium salicylate and aspirin
    • 2-s2.0-0028167846
    • Kopp E., Ghosh S., Inhibition of NF- B by sodium salicylate and aspirin. Science 1994 265 5174 956 959 2-s2.0-0028167846
    • (1994) Science , vol.265 , Issue.5174 , pp. 956-959
    • Kopp, E.1    Ghosh, S.2
  • 120
    • 0029870463 scopus 로고    scopus 로고
    • Salicylates inhibit i B- α; phosphorylation, endothelial-leukocyte adhesion molecule expression, and neutrophil transmigration
    • 2-s2.0-0029870463
    • Pierce J. W., Read M. A., Ding H., Luscinskas F. W., Collins T., Salicylates inhibit I B- α; phosphorylation, endothelial-leukocyte adhesion molecule expression, and neutrophil transmigration. Journal of Immunology 1996 156 10 3961 3969 2-s2.0-0029870463
    • (1996) Journal of Immunology , vol.156 , Issue.10 , pp. 3961-3969
    • Pierce, J.W.1    Read, M.A.2    Ding, H.3    Luscinskas, F.W.4    Collins, T.5
  • 121
    • 0031982964 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase by sodium salicylate leads to inhibition of tumor necrosis factor-induced i B α; phosphorylation and degradation
    • 2-s2.0-0031982964
    • Schwenger P., Alpert D., Skolnik E. Y., Vilček J., Activation of p38 mitogen-activated protein kinase by sodium salicylate leads to inhibition of tumor necrosis factor-induced I B α; phosphorylation and degradation. Molecular and Cellular Biology 1998 18 1 78 84 2-s2.0-0031982964
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.1 , pp. 78-84
    • Schwenger, P.1    Alpert, D.2    Skolnik, E.Y.3    Vilček, J.4
  • 122
    • 0033578879 scopus 로고    scopus 로고
    • Sulindac inhibits activation of the NF- B pathway
    • 2-s2.0-0033578879 10.1074/jbc.274.38.27307
    • Yamamoto Y., Yin M.-J., Lin K.-M., Gaynor R. B., Sulindac inhibits activation of the NF- B pathway. Journal of Biological Chemistry 1999 274 38 27307 27314 2-s2.0-0033578879 10.1074/jbc.274.38.27307
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.38 , pp. 27307-27314
    • Yamamoto, Y.1    Yin, M.-J.2    Lin, K.-M.3    Gaynor, R.B.4
  • 123
    • 0026715172 scopus 로고
    • Thioredoxin regulates the DNA binding activity of N F- B by reduction of a disulphide bond involving cysteine 62
    • 2-s2.0-0026715172
    • Matthews J. R., Wakasugi N., Virelizier J.-L., Yodoi J., Hay R. T., Thioredoxin regulates the DNA binding activity of N F- B by reduction of a disulphide bond involving cysteine 62. Nucleic Acids Research 1992 20 15 3821 3830 2-s2.0-0026715172
    • (1992) Nucleic Acids Research , vol.20 , Issue.15 , pp. 3821-3830
    • Matthews, J.R.1    Wakasugi, N.2    Virelizier, J.-L.3    Yodoi, J.4    Hay, R.T.5
  • 124
    • 3843138492 scopus 로고    scopus 로고
    • Evidence for colorectal cancer cell specificity of aspirin effects on NF B signalling and apoptosis
    • 2-s2.0-3843138492
    • Din F. V. N., Dunlop M. G., Stark L. A., Evidence for colorectal cancer cell specificity of aspirin effects on NF B signalling and apoptosis. British Journal of Cancer 2004 91 2 381 388 2-s2.0-3843138492
    • (2004) British Journal of Cancer , vol.91 , Issue.2 , pp. 381-388
    • Din, F.V.N.1    Dunlop, M.G.2    Stark, L.A.3
  • 125
    • 33750097303 scopus 로고    scopus 로고
    • Therapeutic levels of aspirin and salicylate directly inhibit a model of angiogenesis through a Cox-independent mechanism
    • 2-s2.0-33750097303 10.1096/fj.06-5987com
    • Borthwick G. M., Johnson A. S., Partington M., Burn J., Wilson R., Arthur H. M., Therapeutic levels of aspirin and salicylate directly inhibit a model of angiogenesis through a Cox-independent mechanism. FASEB Journal 2006 20 12 2009 2016 2-s2.0-33750097303 10.1096/fj.06-5987com
    • (2006) FASEB Journal , vol.20 , Issue.12 , pp. 2009-2016
    • Borthwick, G.M.1    Johnson, A.S.2    Partington, M.3    Burn, J.4    Wilson, R.5    Arthur, H.M.6
  • 126
    • 34447099200 scopus 로고    scopus 로고
    • Aspirin activates the NF- B signalling pathway and induces apoptosis in intestinal neoplasia in two in vivo models of human colorectal cancer
    • 2-s2.0-34447099200 10.1093/carcin/bgl220
    • Stark L. A., Reid K., Sansom O. J., Din F. V., Guichard S., Mayer I., Jodrell D. I., Clarke A. R., Dunlop M. G., Aspirin activates the NF- B signalling pathway and induces apoptosis in intestinal neoplasia in two in vivo models of human colorectal cancer. Carcinogenesis 2007 28 5 968 976 2-s2.0-34447099200 10.1093/carcin/bgl220
    • (2007) Carcinogenesis , vol.28 , Issue.5 , pp. 968-976
    • Stark, L.A.1    Reid, K.2    Sansom, O.J.3    Din, F.V.4    Guichard, S.5    Mayer, I.6    Jodrell, D.I.7    Clarke, A.R.8    Dunlop, M.G.9
  • 127
    • 23744505379 scopus 로고    scopus 로고
    • Diclofenac attenuates Wnt/ β -catenin signaling in colon cancer cells by activation of NF- B
    • 2-s2.0-23744505379 10.1016/j.febslet.2005.06.049
    • Cho M., Gwak J., Park S., Won J., Kim D.-E., Sung S. Y., Cha I.-J., Tae K. K., Shin J.-G., Oh S., Diclofenac attenuates Wnt/ β -catenin signaling in colon cancer cells by activation of NF- B. FEBS Letters 2005 579 20 4213 4218 2-s2.0-23744505379 10.1016/j.febslet.2005.06.049
    • (2005) FEBS Letters , vol.579 , Issue.20 , pp. 4213-4218
    • Cho, M.1    Gwak, J.2    Park, S.3    Won, J.4    Kim, D.-E.5    Sung, S.Y.6    Cha, I.-J.7    Tae, K.K.8    Shin, J.-G.9    Oh, S.10
  • 129
    • 0029043582 scopus 로고
    • How MAP kinases are regulated
    • 2-s2.0-0029043582 10.1074/jbc.270.25.14843
    • Cobb M. H., Goldsmith E. J., How MAP kinases are regulated. Journal of Biological Chemistry 1995 270 25 14843 14846 2-s2.0-0029043582 10.1074/jbc.270.25.14843
    • (1995) Journal of Biological Chemistry , vol.270 , Issue.25 , pp. 14843-14846
    • Cobb, M.H.1    Goldsmith, E.J.2
  • 130
    • 0031004569 scopus 로고    scopus 로고
    • Sodium salicylate induces apoptosis via p38 mitogen-activated protein kinase but inhibits tumor necrosis factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activation
    • 2-s2.0-0031004569 10.1073/pnas.94.7.2869
    • Schwenger P., Bellosta P., Vietor I., Basilico C., Skolnik E. Y., Vilček J., Sodium salicylate induces apoptosis via p38 mitogen-activated protein kinase but inhibits tumor necrosis factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activation. Proceedings of the National Academy of Sciences of the United States of America 1997 94 7 2869 2873 2-s2.0-0031004569 10.1073/pnas.94.7.2869
    • (1997) Proceedings of the National Academy of Sciences of the United States of America , vol.94 , Issue.7 , pp. 2869-2873
    • Schwenger, P.1    Bellosta, P.2    Vietor, I.3    Basilico, C.4    Skolnik, E.Y.5    Vilček, J.6
  • 131
    • 0029970288 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor-induced p42/p44 mitogen-activated protein kinase activation by sodium salicylate
    • 2-s2.0-0029970288 10.1074/jbc.271.14.8089
    • Schwenger P., Skolnik E. Y., Vilček J., Inhibition of tumor necrosis factor-induced p42/p44 mitogen-activated protein kinase activation by sodium salicylate. Journal of Biological Chemistry 1996 271 14 8089 8094 2-s2.0-0029970288 10.1074/jbc.271.14.8089
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.14 , pp. 8089-8094
    • Schwenger, P.1    Skolnik, E.Y.2    Vilček, J.3
  • 132
    • 0032750920 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing
    • 2-s2.0-0032750920 10.1038/70995
    • Jones M. K., Wang H., Peskar B. M., Levin E., Itani R. M., Sarfeh I. J., Tarnawski A. S., Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing. Nature Medicine 1999 5 12 1418 1423 2-s2.0-0032750920 10.1038/70995
    • (1999) Nature Medicine , vol.5 , Issue.12 , pp. 1418-1423
    • Jones, M.K.1    Wang, H.2    Peskar, B.M.3    Levin, E.4    Itani, R.M.5    Sarfeh, I.J.6    Tarnawski, A.S.7
  • 133
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • 2-s2.0-0028880006
    • Xia Z., Dickens M., Raingeaud J., Davis R. J., Greenberg M. E., Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995 270 5240 1326 1331 2-s2.0-0028880006
    • (1995) Science , vol.270 , Issue.5240 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5
  • 134
    • 0030980026 scopus 로고    scopus 로고
    • Inhibition of activator protein 1 activity and neoplastic transformation by aspirin
    • 2-s2.0-0030980026 10.1074/jbc.272.15.9962
    • Dong Z., Huang C., Brown R. E., Ma W.-Y., Inhibition of activator protein 1 activity and neoplastic transformation by aspirin. Journal of Biological Chemistry 1997 272 15 9962 9970 2-s2.0-0030980026 10.1074/jbc.272.15.9962
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.15 , pp. 9962-9970
    • Dong, Z.1    Huang, C.2    Brown, R.E.3    Ma, W.-Y.4
  • 135
    • 29244436809 scopus 로고    scopus 로고
    • Nitric oxide-donating aspirin inhibits colon cancer cell growth via mitogen-activated protein kinase activation
    • 2-s2.0-29244436809 10.1124/jpet.105.091363
    • Hundley T. R., Rigas B., Nitric oxide-donating aspirin inhibits colon cancer cell growth via mitogen-activated protein kinase activation. Journal of Pharmacology and Experimental Therapeutics 2006 316 1 25 34 2-s2.0-29244436809 10.1124/jpet.105.091363
    • (2006) Journal of Pharmacology and Experimental Therapeutics , vol.316 , Issue.1 , pp. 25-34
    • Hundley, T.R.1    Rigas, B.2
  • 136
    • 0035984912 scopus 로고    scopus 로고
    • ROS, stress-activated kinases and stress signaling in cancer
    • 2-s2.0-0035984912 10.1093/embo-reports/kvf094
    • Benhar M., Engelberg D., Levitzki A., ROS, stress-activated kinases and stress signaling in cancer. EMBO Reports 2002 3 5 420 425 2-s2.0-0035984912 10.1093/embo-reports/kvf094
    • (2002) EMBO Reports , vol.3 , Issue.5 , pp. 420-425
    • Benhar, M.1    Engelberg, D.2    Levitzki, A.3
  • 137
    • 0037205007 scopus 로고    scopus 로고
    • The promise and perils of Wnt signaling through β -catenin
    • 2-s2.0-0037205007 10.1126/science.1071549
    • Moon R. T., Bowerman B., Boutros M., Perrimon N., The promise and perils of Wnt signaling through β -catenin. Science 2002 296 5573 1644 1646 2-s2.0-0037205007 10.1126/science.1071549
    • (2002) Science , vol.296 , Issue.5573 , pp. 1644-1646
    • Moon, R.T.1    Bowerman, B.2    Boutros, M.3    Perrimon, N.4
  • 138
    • 0035890420 scopus 로고    scopus 로고
    • β -catenin expression is altered in human colonic aberrant crypt foci
    • 2-s2.0-0035890420
    • Hao X. P., Pretlow T. G., Rao J. S., Pretlow T. P., β -catenin expression is altered in human colonic aberrant crypt foci. Cancer Research 2001 61 22 8085 8088 2-s2.0-0035890420
    • (2001) Cancer Research , vol.61 , Issue.22 , pp. 8085-8088
    • Hao, X.P.1    Pretlow, T.G.2    Rao, J.S.3    Pretlow, T.P.4
  • 139
    • 0037041627 scopus 로고    scopus 로고
    • Nuclear β -catenin expression is closely related to ulcerative growth of colorectal carcinoma
    • 2-s2.0-0037041627
    • Chiang J. M., Wu Chou Y. H., Chen T. C., Ng K. F., Lin J. L., Nuclear β -catenin expression is closely related to ulcerative growth of colorectal carcinoma. British Journal of Cancer 2002 86 7 1124 1129 2-s2.0-0037041627
    • (2002) British Journal of Cancer , vol.86 , Issue.7 , pp. 1124-1129
    • Chiang, J.M.1    Wu Chou, Y.H.2    Chen, T.C.3    Ng, K.F.4    Lin, J.L.5
  • 142
    • 57249108188 scopus 로고    scopus 로고
    • Suppression of Wnt/ β -catenin signaling inhibits prostate cancer cell proliferation
    • 2-s2.0-57249108188 10.1016/j.ejphar.2008.10.053
    • Lu W., Tinsley H. N., Keeton A., Qu Z., Piazza G. A., Li Y., Suppression of Wnt/ β -catenin signaling inhibits prostate cancer cell proliferation. European Journal of Pharmacology 2009 602 1 8 14 2-s2.0-57249108188 10.1016/j.ejphar.2008.10.053
    • (2009) European Journal of Pharmacology , vol.602 , Issue.1 , pp. 8-14
    • Lu, W.1    Tinsley, H.N.2    Keeton, A.3    Qu, Z.4    Piazza, G.A.5    Li, Y.6
  • 143
    • 24644487443 scopus 로고    scopus 로고
    • Cadherins and catenins in breast cancer
    • 2-s2.0-24644487443 10.1016/j.ceb.2005.08.014
    • Cowin P., Rowlands T. M., Hatsell S. J., Cadherins and catenins in breast cancer. Current Opinion in Cell Biology 2005 17 5 499 508 2-s2.0-24644487443 10.1016/j.ceb.2005.08.014
    • (2005) Current Opinion in Cell Biology , vol.17 , Issue.5 , pp. 499-508
    • Cowin, P.1    Rowlands, T.M.2    Hatsell, S.J.3
  • 145
    • 0242300130 scopus 로고    scopus 로고
    • Nitric oxide-donating aspirin inhibits β -catenin/T cell factor (TCF) signaling in SW480 colon cancer cells by disrupting the nuclear β -catenin-TCF association
    • 2-s2.0-0242300130 10.1073/pnas.2134840100
    • Nath N., Kashfi K., Chen J., Rigas B., Nitric oxide-donating aspirin inhibits β -catenin/T cell factor (TCF) signaling in SW480 colon cancer cells by disrupting the nuclear β -catenin-TCF association. Proceedings of the National Academy of Sciences of the United States of America 2003 100 22 12584 12589 2-s2.0-0242300130 10.1073/pnas.2134840100
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.22 , pp. 12584-12589
    • Nath, N.1    Kashfi, K.2    Chen, J.3    Rigas, B.4
  • 146
    • 0035252741 scopus 로고    scopus 로고
    • The nonsteroidal anti-inflammatory drugs aspirin and indomethacin attenuate β -catenin/TCF-4 signaling
    • 2-s2.0-0035252741 10.1038/sj.onc.1204123
    • Dihlmann S., Siermann A., Von Knebel Doeberitz M., The nonsteroidal anti-inflammatory drugs aspirin and indomethacin attenuate β -catenin/TCF-4 signaling. Oncogene 2001 20 5 645 653 2-s2.0-0035252741 10.1038/sj.onc.1204123
    • (2001) Oncogene , vol.20 , Issue.5 , pp. 645-653
    • Dihlmann, S.1    Siermann, A.2    Von Knebel Doeberitz, M.3
  • 147
    • 1542649391 scopus 로고    scopus 로고
    • Reduction of beta-catenin/T-cell transcription factor signaling by aspirin and indomethacin is caused by an increased stabilization of phosphorylated beta-catenin
    • 2-s2.0-1542649391
    • Dihlmann S., Klein S., Doeberitz Mv M. V. K., Reduction of beta-catenin/T-cell transcription factor signaling by aspirin and indomethacin is caused by an increased stabilization of phosphorylated beta-catenin. Molecular cancer therapeutics 2003 2 6 509 516 2-s2.0-1542649391
    • (2003) Molecular Cancer Therapeutics , vol.2 , Issue.6 , pp. 509-516
    • Dihlmann, S.1    Klein, S.2    Doeberitz Mv, M.V.K.3
  • 148
    • 33750223793 scopus 로고    scopus 로고
    • Effect of aspirin on the Wnt/ β -catenin pathway is mediated via protein phosphatase 2A
    • 2-s2.0-33750223793 10.1038/sj.onc.1209658
    • Bos C. L., Kodach L. L., Van Den Brink G. R., Diks S. H., Van Santen M. M., Richel D. J., Peppelenbosch M. P., Hardwick J. C. H., Effect of aspirin on the Wnt/ β -catenin pathway is mediated via protein phosphatase 2A. Oncogene 2006 25 49 6447 6456 2-s2.0-33750223793 10.1038/sj.onc.1209658
    • (2006) Oncogene , vol.25 , Issue.49 , pp. 6447-6456
    • Bos, C.L.1    Kodach, L.L.2    Van Den Brink, G.R.3    Diks, S.H.4    Van Santen, M.M.5    Richel, D.J.6    Peppelenbosch, M.P.7    Hardwick, J.C.H.8
  • 149
    • 84868146644 scopus 로고    scopus 로고
    • Aspirin inhibits colon cancer cell and tumor growth and downregulates specificity protein (sp) transcription factors
    • e48208
    • Pathi S., Jutooru I., Chadalapaka G., Nair V., Lee S. O., Safe S., Aspirin inhibits colon cancer cell and tumor growth and downregulates specificity protein (sp) transcription factors. PLoS ONE 2012 7 e48208
    • (2012) PLoS ONE , vol.7
    • Pathi, S.1    Jutooru, I.2    Chadalapaka, G.3    Nair, V.4    Lee, S.O.5    Safe, S.6
  • 150
    • 0642287832 scopus 로고    scopus 로고
    • Sulindac metabolites induce caspase- and proteasome-dependent degradation of beta-catenin protein in human colon cancer cells
    • 2-s2.0-0642287832
    • Rice P. L., Kelloff J., Sullivan H., Driggers L. J., Beard K. S., Kuwada S., Piazza G., Ahnen D. J., Sulindac metabolites induce caspase- and proteasome-dependent degradation of beta-catenin protein in human colon cancer cells. Molecular cancer therapeutics 2003 2 9 885 892 2-s2.0-0642287832
    • (2003) Molecular Cancer Therapeutics , vol.2 , Issue.9 , pp. 885-892
    • Rice, P.L.1    Kelloff, J.2    Sullivan, H.3    Driggers, L.J.4    Beard, K.S.5    Kuwada, S.6    Piazza, G.7    Ahnen, D.J.8
  • 151
    • 33745952028 scopus 로고    scopus 로고
    • Growth inhibition of mesenchymal stem cells by aspirin: Involvement of the wnt/ β -catenin signal pathway
    • 2-s2.0-33745952028 10.1111/j.1440-1681.2006.04432.x
    • Wang Y., Chen X., Zhu W., Zhang H., Hu S., Cong X., Growth inhibition of mesenchymal stem cells by aspirin: involvement of the wnt/ β -catenin signal pathway. Clinical and Experimental Pharmacology and Physiology 2006 33 8 696 701 2-s2.0-33745952028 10.1111/j.1440-1681.2006.04432.x
    • (2006) Clinical and Experimental Pharmacology and Physiology , vol.33 , Issue.8 , pp. 696-701
    • Wang, Y.1    Chen, X.2    Zhu, W.3    Zhang, H.4    Hu, S.5    Cong, X.6
  • 152
    • 0036830654 scopus 로고    scopus 로고
    • Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve β -catenin and cyclin D1 down-regulation
    • 2-s2.0-0036830654 10.1016/S0006-2952(02)01345-X
    • Li H., Liu L., David M. L., Whitehead C. M., Chen M., Fetter J. R., Sperl G. J., Pamukcu R., Thompson W. J., Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve β -catenin and cyclin D1 down-regulation. Biochemical Pharmacology 2002 64 9 1325 1336 2-s2.0-0036830654 10.1016/S0006-2952(02)01345-X
    • (2002) Biochemical Pharmacology , vol.64 , Issue.9 , pp. 1325-1336
    • Li, H.1    Liu, L.2    David, M.L.3    Whitehead, C.M.4    Chen, M.5    Fetter, J.R.6    Sperl, G.J.7    Pamukcu, R.8    Thompson, W.J.9
  • 153
    • 70350464124 scopus 로고    scopus 로고
    • Aspirin induces apoptosis in mesenchymal stem cells requiring Wnt/ β -catenin pathway
    • 2-s2.0-70350464124 10.1111/j.1365-2184.2009.00639.x
    • Deng L., Hu S., Baydoun A. R., Chen J., Chen X., Cong X., Aspirin induces apoptosis in mesenchymal stem cells requiring Wnt/ β -catenin pathway. Cell Proliferation 2009 42 6 721 730 2-s2.0-70350464124 10.1111/j.1365-2184. 2009.00639.x
    • (2009) Cell Proliferation , vol.42 , Issue.6 , pp. 721-730
    • Deng, L.1    Hu, S.2    Baydoun, A.R.3    Chen, J.4    Chen, X.5    Cong, X.6
  • 154
    • 33746061276 scopus 로고    scopus 로고
    • Nitric oxide-releasing aspirin and indomethacin are potent inhibitors against colon cancer in azoxymethane-treated rats: Effects on molecular targets
    • 2-s2.0-33746061276 10.1158/1535-7163.MCT-06-0061
    • Rao C. V., Reddy B. S., Steele V. E., Wang C.-X., Liu X., Ouyang N., Patlolla J. M. R., Simi B., Kopelovich L., Rigas B., Nitric oxide-releasing aspirin and indomethacin are potent inhibitors against colon cancer in azoxymethane-treated rats: effects on molecular targets. Molecular Cancer Therapeutics 2006 5 6 1530 1538 2-s2.0-33746061276 10.1158/1535-7163.MCT-06-0061
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.6 , pp. 1530-1538
    • Rao, C.V.1    Reddy, B.S.2    Steele, V.E.3    Wang, C.-X.4    Liu, X.5    Ouyang, N.6    Patlolla, J.M.R.7    Simi, B.8    Kopelovich, L.9    Rigas, B.10
  • 155
    • 70349454049 scopus 로고    scopus 로고
    • Nitro-aspirin inhibits MCF-7 breast cancer cell growth: Effects on COX-2 expression and Wnt/ β -catenin/TCF-4 signaling
    • 2-s2.0-70349454049 10.1016/j.bcp.2009.06.104
    • Nath N., Vassell R., Chattopadhyay M., Kogan M., Kashfi K., Nitro-aspirin inhibits MCF-7 breast cancer cell growth: effects on COX-2 expression and Wnt/ β -catenin/TCF-4 signaling. Biochemical Pharmacology 2009 78 10 1298 1304 2-s2.0-70349454049 10.1016/j.bcp.2009.06.104
    • (2009) Biochemical Pharmacology , vol.78 , Issue.10 , pp. 1298-1304
    • Nath, N.1    Vassell, R.2    Chattopadhyay, M.3    Kogan, M.4    Kashfi, K.5
  • 156
    • 84866691169 scopus 로고    scopus 로고
    • Phosphosulindac (OXT-328) selectively targets breast cancer stem cells in vitro and in human breast cancer xenografts
    • Zhu C., Cheng K. W., Ouyang N., Phosphosulindac (OXT-328) selectively targets breast cancer stem cells in vitro and in human breast cancer xenografts. Stem Cells 2012 30 2065 2075
    • (2012) Stem Cells , vol.30 , pp. 2065-2075
    • Zhu, C.1    Cheng, K.W.2    Ouyang, N.3
  • 157
    • 33947545295 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and oxidative stress in cancer cells
    • 2-s2.0-33947545295
    • Adachi M., Sakamoto H., Kawamura R., Wang W., Imai K., Shinomura Y., Nonsteroidal anti-inflammatory drugs and oxidative stress in cancer cells. Histology and Histopathology 2007 22 4-6 437 442 2-s2.0-33947545295
    • (2007) Histology and Histopathology , vol.22 , Issue.4-6 , pp. 437-442
    • Adachi, M.1    Sakamoto, H.2    Kawamura, R.3    Wang, W.4    Imai, K.5    Shinomura, Y.6
  • 158
    • 36749022313 scopus 로고    scopus 로고
    • Novel agents for cancer prevention based on nitric oxide
    • 2-s2.0-36749022313 10.1042/BST0351364
    • Rigas B., Novel agents for cancer prevention based on nitric oxide. Biochemical Society Transactions 2007 35 5 1364 1368 2-s2.0-36749022313 10.1042/BST0351364
    • (2007) Biochemical Society Transactions , vol.35 , Issue.5 , pp. 1364-1368
    • Rigas, B.1
  • 159
    • 0142138618 scopus 로고    scopus 로고
    • The metabolism of sulindac enhances its scavenging activity against reactive oxygen and nitrogen species
    • 2-s2.0-0142138618 10.1016/S0891-5849(03)00437-4
    • Fernandes E., Toste S. A., Lima J. L. F. C., Reis S., The metabolism of sulindac enhances its scavenging activity against reactive oxygen and nitrogen species. Free Radical Biology and Medicine 2003 35 9 1008 1017 2-s2.0-0142138618 10.1016/S0891-5849(03)00437-4
    • (2003) Free Radical Biology and Medicine , vol.35 , Issue.9 , pp. 1008-1017
    • Fernandes, E.1    Toste, S.A.2    Lima, J.L.F.C.3    Reis, S.4
  • 160
    • 16244417812 scopus 로고    scopus 로고
    • Hydrogen peroxide scavenging activity by non-steroidal anti-inflammatory drugs
    • 2-s2.0-16244417812 10.1016/j.lfs.2004.10.052
    • Costa D., Gomes A., Reis S., Lima J. L. F. C., Fernandes E., Hydrogen peroxide scavenging activity by non-steroidal anti-inflammatory drugs. Life Sciences 2005 76 24 2841 2848 2-s2.0-16244417812 10.1016/j.lfs.2004.10.052
    • (2005) Life Sciences , vol.76 , Issue.24 , pp. 2841-2848
    • Costa, D.1    Gomes, A.2    Reis, S.3    Lima, J.L.F.C.4    Fernandes, E.5
  • 161
    • 0036628762 scopus 로고    scopus 로고
    • Prevention of hypertension, hyperglycemia and vascular oxidative stress by aspirin treatment in chronically glucose-fed rats
    • 2-s2.0-0036628762 10.1097/00004872-200207000-00028
    • El Midaoui A., Wu R., De Champlain J., Prevention of hypertension, hyperglycemia and vascular oxidative stress by aspirin treatment in chronically glucose-fed rats. Journal of Hypertension 2002 20 7 1407 1412 2-s2.0-0036628762 10.1097/00004872-200207000-00028
    • (2002) Journal of Hypertension , vol.20 , Issue.7 , pp. 1407-1412
    • El Midaoui, A.1    Wu, R.2    De Champlain, J.3
  • 162
    • 40649106179 scopus 로고    scopus 로고
    • Acetylsalicylic acid provides cerebrovascular protection from oxidant damage in salt-loaded stroke-prone rats
    • 2-s2.0-40649106179 10.1016/j.lfs.2008.01.017
    • Ishizuka T., Niwa A., Tabuchi M., Ooshima K., Higashino H., Acetylsalicylic acid provides cerebrovascular protection from oxidant damage in salt-loaded stroke-prone rats. Life Sciences 2008 82 13-14 806 815 2-s2.0-40649106179 10.1016/j.lfs.2008.01.017
    • (2008) Life Sciences , vol.82 , Issue.13-14 , pp. 806-815
    • Ishizuka, T.1    Niwa, A.2    Tabuchi, M.3    Ooshima, K.4    Higashino, H.5
  • 163
    • 0025152819 scopus 로고
    • Protective action of aspirin in experimental myocardial infarction induced by isoproterenol in rats and its effect on lipid peroxidation
    • 2-s2.0-0025152819
    • Kumari S. S., Varghese A., Muraleedharan D., Menon V. P., Protective action of aspirin in experimental myocardial infarction induced by isoproterenol in rats and its effect on lipid peroxidation. Indian Journal of Experimental Biology 1990 28 5 480 485 2-s2.0-0025152819
    • (1990) Indian Journal of Experimental Biology , vol.28 , Issue.5 , pp. 480-485
    • Kumari, S.S.1    Varghese, A.2    Muraleedharan, D.3    Menon, V.P.4
  • 164
    • 2442517591 scopus 로고    scopus 로고
    • Protective effects and mechanism of action of aspirin on focal cerebral ischemia-reperfusion in rats
    • 2-s2.0-2442517591
    • Qiu L.-Y., Yu J., Zhou Y., Chen C.-H., Protective effects and mechanism of action of aspirin on focal cerebral ischemia-reperfusion in rats. Yaoxue Xuebao 2003 38 8 561 564 2-s2.0-2442517591
    • (2003) Yaoxue Xuebao , vol.38 , Issue.8 , pp. 561-564
    • Qiu, L.-Y.1    Yu, J.2    Zhou, Y.3    Chen, C.-H.4
  • 165
    • 33846065151 scopus 로고    scopus 로고
    • Aspirin restores normal baroreflex function in hypercholesterolemic rats by its antioxidative action
    • 2-s2.0-33846065151 10.1016/j.ejphar.2006.11.029
    • Tauseef M., Sharma K. K., Fahim M., Aspirin restores normal baroreflex function in hypercholesterolemic rats by its antioxidative action. European Journal of Pharmacology 2007 556 1-3 136 143 2-s2.0-33846065151 10.1016/j.ejphar.2006.11.029
    • (2007) European Journal of Pharmacology , vol.556 , Issue.1-3 , pp. 136-143
    • Tauseef, M.1    Sharma, K.K.2    Fahim, M.3
  • 166
    • 45549098786 scopus 로고    scopus 로고
    • Antioxidative effects of nonsteroidal anti-inflammatory drugs during the initiation stages of experimental colon carcinogenesis in rats
    • 2-s2.0-45549098786
    • Kanwar S. S., Vaiphei K., Nehru B., Sanyal S. N., Antioxidative effects of nonsteroidal anti-inflammatory drugs during the initiation stages of experimental colon carcinogenesis in rats. Journal of Environmental Pathology, Toxicology and Oncology 2008 27 2 89 100 2-s2.0-45549098786
    • (2008) Journal of Environmental Pathology, Toxicology and Oncology , vol.27 , Issue.2 , pp. 89-100
    • Kanwar, S.S.1    Vaiphei, K.2    Nehru, B.3    Sanyal, S.N.4
  • 167
    • 60049096828 scopus 로고    scopus 로고
    • Protective effect of salicylates against hydrogen peroxide stress in yeast
    • 2-s2.0-60049096828 10.1111/j.1365-2672.2008.04061.x
    • Yiannakopoulou E. C., Tiligada E., Protective effect of salicylates against hydrogen peroxide stress in yeast. Journal of Applied Microbiology 2009 106 3 903 908 2-s2.0-60049096828 10.1111/j.1365-2672.2008.04061.x
    • (2009) Journal of Applied Microbiology , vol.106 , Issue.3 , pp. 903-908
    • Yiannakopoulou, E.C.1    Tiligada, E.2
  • 168
    • 0032762624 scopus 로고    scopus 로고
    • Reactive oxygen species are involved in the apoptosis induced by nonsteroidal anti-inflammatory drugs in cultured gastric cells
    • 2-s2.0-0032762624 10.1016/S0014-2999(99)00599-3
    • Kusuhara H., Komatsu H., Sumichika H., Sugahara K., Reactive oxygen species are involved in the apoptosis induced by nonsteroidal anti-inflammatory drugs in cultured gastric cells. European Journal of Pharmacology 1999 383 3 331 337 2-s2.0-0032762624 10.1016/S0014-2999(99)00599-3
    • (1999) European Journal of Pharmacology , vol.383 , Issue.3 , pp. 331-337
    • Kusuhara, H.1    Komatsu, H.2    Sumichika, H.3    Sugahara, K.4
  • 169
    • 0032485472 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs, short-chain fatty acids, and reactive oxygen metabolism in human colorectal cancer cells
    • 2-s2.0-0032485472 10.1016/S0167-4889(97)00140-7
    • Giardina C., Inan M. S., Nonsteroidal anti-inflammatory drugs, short-chain fatty acids, and reactive oxygen metabolism in human colorectal cancer cells. Biochimica et Biophysica Acta 1998 1401 3 277 288 2-s2.0-0032485472 10.1016/S0167-4889(97)00140-7
    • (1998) Biochimica et Biophysica Acta , vol.1401 , Issue.3 , pp. 277-288
    • Giardina, C.1    Inan, M.S.2
  • 170
    • 0037441392 scopus 로고    scopus 로고
    • Molecular ordering of ROS production, mitochondrial changes, and caspase activation during sodium salicylate-induced apoptosis
    • 2-s2.0-0037441392 10.1016/S0891-5849(02)01301-1
    • Chung Y. M., Bae Y. S., Lee S. Y., Molecular ordering of ROS production, mitochondrial changes, and caspase activation during sodium salicylate-induced apoptosis. Free Radical Biology and Medicine 2003 34 4 434 442 2-s2.0-0037441392 10.1016/S0891-5849(02)01301-1
    • (2003) Free Radical Biology and Medicine , vol.34 , Issue.4 , pp. 434-442
    • Chung, Y.M.1    Bae, Y.S.2    Lee, S.Y.3
  • 171
    • 22344434243 scopus 로고    scopus 로고
    • Sulindac enhances the proteasome inhibitor bortezomib-mediated oxidative stress and anticancer activity
    • 2-s2.0-22344434243 10.1158/1078-0432.CCR-05-0085
    • Minami T., Adachi M., Kawamura R., Zhang Y., Shinomura Y., Imai K., Sulindac enhances the proteasome inhibitor bortezomib-mediated oxidative stress and anticancer activity. Clinical Cancer Research 2005 11 14 5248 5256 2-s2.0-22344434243 10.1158/1078-0432.CCR-05-0085
    • (2005) Clinical Cancer Research , vol.11 , Issue.14 , pp. 5248-5256
    • Minami, T.1    Adachi, M.2    Kawamura, R.3    Zhang, Y.4    Shinomura, Y.5    Imai, K.6
  • 172
    • 49349100455 scopus 로고    scopus 로고
    • Redox control and oxidative stress in yeast cells
    • 2-s2.0-49349100455 10.1016/j.bbagen.2007.12.004
    • Herrero E., Ros J., Bellí G., Cabiscol E., Redox control and oxidative stress in yeast cells. Biochimica et Biophysica Acta 2008 1780 11 1217 1235 2-s2.0-49349100455 10.1016/j.bbagen.2007.12.004
    • (2008) Biochimica et Biophysica Acta , vol.1780 , Issue.11 , pp. 1217-1235
    • Herrero, E.1    Ros, J.2    Bellí, G.3    Cabiscol, E.4
  • 173
    • 26644432066 scopus 로고    scopus 로고
    • Oxidative stress is responsible for mitochondrial permeability transition induction by salicylate in liver mitochondria
    • 2-s2.0-26644432066 10.1074/jbc.M502391200
    • Battaglia V., Salvi M., Toninello A., Oxidative stress is responsible for mitochondrial permeability transition induction by salicylate in liver mitochondria. Journal of Biological Chemistry 2005 280 40 33864 33872 2-s2.0-26644432066 10.1074/jbc.M502391200
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.40 , pp. 33864-33872
    • Battaglia, V.1    Salvi, M.2    Toninello, A.3
  • 174
    • 84860480140 scopus 로고    scopus 로고
    • Implications of altered glutathione metabolism in aspirin-induced oxidative stress and mitochondrial dysfunction in HepG2 cells
    • 2-s2.0-84860480140 10.1371/journal.pone.0036325 e36325
    • Raza H., John A., Implications of altered glutathione metabolism in aspirin-induced oxidative stress and mitochondrial dysfunction in HepG2 cells. PLoS ONE 2012 7 4 2-s2.0-84860480140 10.1371/journal.pone.0036325 e36325
    • (2012) PLoS ONE , vol.7 , Issue.4
    • Raza, H.1    John, A.2
  • 175
    • 27744593467 scopus 로고    scopus 로고
    • Metabolic aspects of aspirin-induced apoptosis in yeast
    • 2-s2.0-27744593467 10.1016/j.femsyr.2005.05.001
    • Sapienza K., Balzan R., Metabolic aspects of aspirin-induced apoptosis in yeast. FEMS Yeast Research 2005 5 12 1207 1213 2-s2.0-27744593467 10.1016/j.femsyr.2005.05.001
    • (2005) FEMS Yeast Research , vol.5 , Issue.12 , pp. 1207-1213
    • Sapienza, K.1    Balzan, R.2
  • 176
    • 33745087154 scopus 로고    scopus 로고
    • Survivin, a cancer target with an emerging role in normal adult tissues
    • 2-s2.0-33745087154 10.1158/1535-7163.MCT-05-0375
    • Fukuda S., Pelus L. M., Survivin, a cancer target with an emerging role in normal adult tissues. Molecular Cancer Therapeutics 2006 5 5 1087 1098 2-s2.0-33745087154 10.1158/1535-7163.MCT-05-0375
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.5 , pp. 1087-1098
    • Fukuda, S.1    Pelus, L.M.2
  • 177
    • 49649095644 scopus 로고    scopus 로고
    • Aspirin sensitizes cancer cells to TRAIL-induced apoptosis by reducing survivin levels
    • 2-s2.0-49649095644 10.1158/1078-0432.CCR-07-4362
    • Lu M., Strohecker A., Chen F., Kwan T., Bosman J., Jordan V. C., Cryns V. L., Aspirin sensitizes cancer cells to TRAIL-induced apoptosis by reducing survivin levels. Clinical Cancer Research 2008 14 10 3168 3176 2-s2.0-49649095644 10.1158/1078-0432.CCR-07-4362
    • (2008) Clinical Cancer Research , vol.14 , Issue.10 , pp. 3168-3176
    • Lu, M.1    Strohecker, A.2    Chen, F.3    Kwan, T.4    Bosman, J.5    Jordan, V.C.6    Cryns, V.L.7
  • 178
    • 0036510539 scopus 로고    scopus 로고
    • Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2
    • 2-s2.0-0036510539 10.1074/jbc.M106043200
    • Wang M., Tan Z., Zhang R., Kotenko S. V., Liang P., Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2. Journal of Biological Chemistry 2002 277 9 7341 7347 2-s2.0-0036510539 10.1074/jbc.M106043200
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.9 , pp. 7341-7347
    • Wang, M.1    Tan, Z.2    Zhang, R.3    Kotenko, S.V.4    Liang, P.5
  • 182
    • 20044366739 scopus 로고    scopus 로고
    • Selective induction of cell cycle arrest and apoptosis in human prostate cancer cells through adenoviral transfer of the melanoma differentiation- associated-7 (mda-7)/interleukin-24 (IL-24) gene
    • 2-s2.0-20044366739 10.1038/sj.cgt.7700780
    • Saito Y., Miyahara R., Gopalan B., Litvak A., Inoue S., Shanker M., Branch C. D., Mhashilkar A. M., Roth J. A., Chada S., Ramesh R., Selective induction of cell cycle arrest and apoptosis in human prostate cancer cells through adenoviral transfer of the melanoma differentiation- associated-7 (mda-7)/interleukin-24 (IL-24) gene. Cancer Gene Therapy 2005 12 3 238 247 2-s2.0-20044366739 10.1038/sj.cgt.7700780
    • (2005) Cancer Gene Therapy , vol.12 , Issue.3 , pp. 238-247
    • Saito, Y.1    Miyahara, R.2    Gopalan, B.3    Litvak, A.4    Inoue, S.5    Shanker, M.6    Branch, C.D.7    Mhashilkar, A.M.8    Roth, J.A.9    Chada, S.10    Ramesh, R.11
  • 184
    • 58949094558 scopus 로고    scopus 로고
    • Chemopreventive agents induce oxidative stress in cancer cells leading to COX-2 overexpression and COX-2-independent cell death
    • 2-s2.0-58949094558 10.1093/carcin/bgn242
    • Sun Y., Chen J., Rigas B., Chemopreventive agents induce oxidative stress in cancer cells leading to COX-2 overexpression and COX-2-independent cell death. Carcinogenesis 2009 30 1 93 100 2-s2.0-58949094558 10.1093/carcin/bgn242
    • (2009) Carcinogenesis , vol.30 , Issue.1 , pp. 93-100
    • Sun, Y.1    Chen, J.2    Rigas, B.3
  • 185
    • 41649096518 scopus 로고    scopus 로고
    • Induction of oxidative stress as a mechanism of action of chemopreventive agents against cancer
    • 2-s2.0-41649096518 10.1038/sj.bjc.6604225
    • Rigas B., Sun Y., Induction of oxidative stress as a mechanism of action of chemopreventive agents against cancer. British Journal of Cancer 2008 98 7 1157 1160 2-s2.0-41649096518 10.1038/sj.bjc.6604225
    • (2008) British Journal of Cancer , vol.98 , Issue.7 , pp. 1157-1160
    • Rigas, B.1    Sun, Y.2
  • 187
    • 0035889658 scopus 로고    scopus 로고
    • Mn-SOD antisense upregulates in vivo apoptosis of squamous cell carcinoma cells by anticancer drugs and γ -rays regulating expression of the BcL-2 family proteins, COX-2 and p21
    • 2-s2.0-0035889658 10.1002/ijc.1513
    • Ueta E., Yoneda K., Kimura T., Tatemoto Y., Doi S., Yamamoto T., Osaki T., Mn-SOD antisense upregulates in vivo apoptosis of squamous cell carcinoma cells by anticancer drugs and γ -rays regulating expression of the BcL-2 family proteins, COX-2 and p21. International Journal of Cancer 2001 94 4 545 550 2-s2.0-0035889658 10.1002/ijc.1513
    • (2001) International Journal of Cancer , vol.94 , Issue.4 , pp. 545-550
    • Ueta, E.1    Yoneda, K.2    Kimura, T.3    Tatemoto, Y.4    Doi, S.5    Yamamoto, T.6    Osaki, T.7


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