메뉴 건너뛰기




Volumn 81, Issue 2, 1999, Pages 294-299

Aspirin induces cell death and caspase-dependent phosphatidylserine externalization in HT-29 human colon adenocarcinoma cells

Author keywords

Apoptosis; Aspirin; Caspases; Colon cancer; HT 29

Indexed keywords

ACETYLSALICYLIC ACID; CASPASE; CASPASE INHIBITOR; DNA FRAGMENT; LIPOCORTIN 5; PHOSPHATIDYLSERINE;

EID: 0032878530     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690690     Document Type: Article
Times cited : (35)

References (53)
  • 2
    • 0031985225 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drug effect on crypt cell proliferation and apoptosis during initiation of rat colon carcinogenesis
    • Barnes CJ, Cameron IL, Hardman WE and Lee M (1998) Non-steroidal anti-inflammatory drug effect on crypt cell proliferation and apoptosis during initiation of rat colon carcinogenesis. Br J Cancer 77: 573-580
    • (1998) Br J Cancer , vol.77 , pp. 573-580
    • Barnes, C.J.1    Cameron, I.L.2    Hardman, W.E.3    Lee, M.4
  • 4
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF-κB in preventing TNF-α-induced cell death
    • Beg AA and Baltimore D (1996) An essential role for NF-κB in preventing TNF-α-induced cell death. Science 274: 782-784
    • (1996) Science , vol.274 , pp. 782-784
    • Beg, A.A.1    Baltimore, D.2
  • 5
    • 7144251162 scopus 로고    scopus 로고
    • Nitrogen mustard up-regulates Bcl-2 and GSH and increases NTP and PCr in HT-29 colon cancer cells
    • Boddie AW, Constantinou A, Williams C and Reed A (1998) Nitrogen mustard up-regulates Bcl-2 and GSH and increases NTP and PCr in HT-29 colon cancer cells. Br J Cancer 77: 1395-1404
    • (1998) Br J Cancer , vol.77 , pp. 1395-1404
    • Boddie, A.W.1    Constantinou, A.2    Williams, C.3    Reed, A.4
  • 9
    • 0030931876 scopus 로고    scopus 로고
    • Caspases; the executioners of apoptosis
    • Cohen GM (1997) Caspases; the executioners of apoptosis. Biochem J 326: 1-16
    • (1997) Biochem J , vol.326 , pp. 1-16
    • Cohen, G.M.1
  • 10
    • 2642689658 scopus 로고    scopus 로고
    • Proteases to die for
    • Cryns V and Yuan J (1998) Proteases to die for. Genes Dev 12: 1551-1557
    • (1998) Genes Dev , vol.12 , pp. 1551-1557
    • Cryns, V.1    Yuan, J.2
  • 11
    • 0002230857 scopus 로고
    • Morphological and biochemical assays of apoptosis
    • Coligan JE and Kruisbeak AM (eds), John Wiley & Sons: New York
    • Duke RC and Cohen JJ (1992) Morphological and biochemical assays of apoptosis. In: Current Protocols in Immunology, Coligan JE and Kruisbeak AM (eds), pp. 3.17.1-3.17.16. John Wiley & Sons: New York
    • (1992) Current Protocols in Immunology , pp. 3171-31716
    • Duke, R.C.1    Cohen, J.J.2
  • 13
    • 0031924535 scopus 로고    scopus 로고
    • COX-2 inhibitor for colorectal cancer
    • Elder DJ and Paraskeva C (1998) COX-2 inhibitor for colorectal cancer. Nat Med 4: 392-393
    • (1998) Nat Med , vol.4 , pp. 392-393
    • Elder, D.J.1    Paraskeva, C.2
  • 14
    • 0030002547 scopus 로고    scopus 로고
    • Differential growth inhibition by the aspirin metabolite salicylate in human colorectal tumor cell lines; enhanced apoptosis in carcinoma and in vitro-transformed adenoma relative to adenoma cell lines
    • Elder DJ, Hague A, Hicks DJ and Paraskeva C (1996) Differential growth inhibition by the aspirin metabolite salicylate in human colorectal tumor cell lines; enhanced apoptosis in carcinoma and in vitro-transformed adenoma relative to adenoma cell lines. Cancer Res 56: 2273-2276
    • (1996) Cancer Res , vol.56 , pp. 2273-2276
    • Elder, D.J.1    Hague, A.2    Hicks, D.J.3    Paraskeva, C.4
  • 15
    • 0030879456 scopus 로고    scopus 로고
    • Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase 2 (COX-2) selective nonsteroidal anti inflammatory drug: Independence from COX 2 protein expression
    • Elder DJE, Halton DE, Hague A and Paraskeva C (1997) Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase 2 (COX-2) selective nonsteroidal anti inflammatory drug: independence from COX 2 protein expression. Clin Cancer Res 3: 1679-1983
    • (1997) Clin Cancer Res , vol.3 , pp. 1679-1983
    • Elder, D.J.E.1    Halton, D.E.2    Hague, A.3    Paraskeva, C.4
  • 16
    • 0031957722 scopus 로고    scopus 로고
    • Aspirin, NSAIDs, and colon career prevention: Mechanisms?
    • Gupta RA and DuBois RN (1998) Aspirin, NSAIDs, and colon career prevention: mechanisms? Gastroenterology 114: 1095-1100
    • (1998) Gastroenterology , vol.114 , pp. 1095-1100
    • Gupta, R.A.1    DuBois, R.N.2
  • 17
    • 0028589378 scopus 로고
    • Regulation of cell number in the mammalian gastrointestinal tract: The importance of apoptosis
    • Hall PA, Coates PJ, Ansari B and Hopwood D (1994) Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosis. J Cell Sci 107: 3569-3577
    • (1994) J Cell Sci , vol.107 , pp. 3569-3577
    • Hall, P.A.1    Coates, P.J.2    Ansari, B.3    Hopwood, D.4
  • 18
    • 0028286187 scopus 로고
    • Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines
    • Heerdt BG, Houston MA and Augenlicht LH (1994) Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines. Cancer Res 54: 3288-3294
    • (1994) Cancer Res , vol.54 , pp. 3288-3294
    • Heerdt, B.G.1    Houston, M.A.2    Augenlicht, L.H.3
  • 20
    • 0030999750 scopus 로고    scopus 로고
    • Apoptosis and the dilemma of cancer chemotherapy
    • Hannun YA (1997) Apoptosis and the dilemma of cancer chemotherapy. Blood 89: 1845-1853
    • (1997) Blood , vol.89 , pp. 1845-1853
    • Hannun, Y.A.1
  • 21
    • 0028229125 scopus 로고
    • Molecular control of apoptosis: Differentiation/growth arrest primary response genes, proto-oncogenes, and tumor supressor genes as positive and negative modulators
    • Hoffman B and Liebermann DA (1994) Molecular control of apoptosis: differentiation/growth arrest primary response genes, proto-oncogenes, and tumor supressor genes as positive and negative modulators. Oncogene 9: 1807-1812
    • (1994) Oncogene , vol.9 , pp. 1807-1812
    • Hoffman, B.1    Liebermann, D.A.2
  • 22
    • 0040298568 scopus 로고    scopus 로고
    • Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
    • Janicke RU, Sprengart ML, Wati MR and Porter AG (1998) Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J Biol Chem 273: 9357-9360
    • (1998) J Biol Chem , vol.273 , pp. 9357-9360
    • Janicke, R.U.1    Sprengart, M.L.2    Wati, M.R.3    Porter, A.G.4
  • 23
    • 0028167846 scopus 로고
    • Inhibition of NF-κB by sodium salicylate and aspirin
    • Kopp E and Ghosh S (1994) Inhibition of NF-κB by sodium salicylate and aspirin. Science 265: 956-959
    • (1994) Science , vol.265 , pp. 956-959
    • Kopp, E.1    Ghosh, S.2
  • 24
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 25
    • 0030298294 scopus 로고    scopus 로고
    • Dissection of TNF receptor 1 effector functions. JNK activation is not linked to apoptosis while NF-κB activation prevents cell death
    • Liu ZG, Hsu H, Goeddel DV and Karin M (1996) Dissection of TNF receptor 1 effector functions. JNK activation is not linked to apoptosis while NF-κB activation prevents cell death. Cell 87: 565-576
    • (1996) Cell , vol.87 , pp. 565-576
    • Liu, Z.G.1    Hsu, H.2    Goeddel, D.V.3    Karin, M.4
  • 26
    • 0029117289 scopus 로고
    • Nonsteroidal antiinflammatory drugs cause apoptosis and induce cyclooxygenases in chicken embryo fibroblasts
    • Lu X, Xie W, Reed D, Bradshaw WS and Simmons DL (1995) Nonsteroidal antiinflammatory drugs cause apoptosis and induce cyclooxygenases in chicken embryo fibroblasts. Proc Natl Acad Sci USA 92: 7961-7965
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7961-7965
    • Lu, X.1    Xie, W.2    Reed, D.3    Bradshaw, W.S.4    Simmons, D.L.5
  • 27
    • 0031984653 scopus 로고    scopus 로고
    • All-trans retinoic acid (ATRA)-induced apoptosis is preceded by G1 arrest in human MCF-7 breast cancer cells
    • Mangiarotti R, Danova M, Alberici R and Pellicciari C (1998) All-trans retinoic acid (ATRA)-induced apoptosis is preceded by G1 arrest in human MCF-7 breast cancer cells. Br J Cancer 77: 186-191
    • (1998) Br J Cancer , vol.77 , pp. 186-191
    • Mangiarotti, R.1    Danova, M.2    Alberici, R.3    Pellicciari, C.4
  • 28
    • 0029802815 scopus 로고    scopus 로고
    • Phosphatidylserine externalization during CD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity
    • Martin SJ, Finucane DM, Amarante-Mendes GP, O'Brien GA and Green DR (1996) Phosphatidylserine externalization during CD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity. J Biol Chem 271: 28753-28756
    • (1996) J Biol Chem , vol.271 , pp. 28753-28756
    • Martin, S.J.1    Finucane, D.M.2    Amarante-Mendes, G.P.3    O'Brien, G.A.4    Green, D.R.5
  • 29
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 30
    • 0027217084 scopus 로고
    • Apoptotic death in epithelial cells: Cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation
    • Oberhammer F, Wilson JW, Dive C, Morris ID, Hickman JA, Wakeling AE, Walker PR and Sikorska M (1993) Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J 12: 3679-3684
    • (1993) EMBO J , vol.12 , pp. 3679-3684
    • Oberhammer, F.1    Wilson, J.W.2    Dive, C.3    Morris, I.D.4    Hickman, J.A.5    Wakeling, A.E.6    Walker, P.R.7    Sikorska, M.8
  • 33
    • 0030968757 scopus 로고    scopus 로고
    • Apoptosis primarily accounts for the growth-inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest, and p53 induction
    • Piazza GA, Rahm AK, Finn TS, Fryer BH, Li H, Stoumen AL, Pamukeu R and Ahnen DJ (1997) Apoptosis primarily accounts for the growth-inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest, and p53 induction. Cancer Res 57: 2452-2459
    • (1997) Cancer Res , vol.57 , pp. 2452-2459
    • Piazza, G.A.1    Rahm, A.K.2    Finn, T.S.3    Fryer, B.H.4    Li, H.5    Stoumen, A.L.6    Pamukeu, R.7    Ahnen, D.J.8
  • 34
    • 0031911922 scopus 로고    scopus 로고
    • Effect of aspirin on induction of apoptosis in HT-29 human colon adenocarcinoma cells
    • Qiao L, Hanif R, Sphicas E, Shiff SJ and Rigas B (1998) Effect of aspirin on induction of apoptosis in HT-29 human colon adenocarcinoma cells. Biochem Pharmacol 55: 53-64
    • (1998) Biochem Pharmacol , vol.55 , pp. 53-64
    • Qiao, L.1    Hanif, R.2    Sphicas, E.3    Shiff, S.J.4    Rigas, B.5
  • 36
    • 0031982964 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase by sodium salicylate leads to inhibition of tumor necrosis factor-induced I kappaB alpha phosphorylation and degradation
    • Schwenger P, Alpert D, Skolnik EY and Vilcek J (1998) Activation of p38 mitogen-activated protein kinase by sodium salicylate leads to inhibition of tumor necrosis factor-induced I kappaB alpha phosphorylation and degradation. Mol Cell Biol 18: 78-84
    • (1998) Mol Cell Biol , vol.18 , pp. 78-84
    • Schwenger, P.1    Alpert, D.2    Skolnik, E.Y.3    Vilcek, J.4
  • 37
    • 0031213555 scopus 로고    scopus 로고
    • 7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53
    • Shao RG, Shimizu T and Pommier Y (1997) 7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53. Exp Cell Res 234: 388-397
    • (1997) Exp Cell Res , vol.234 , pp. 388-397
    • Shao, R.G.1    Shimizu, T.2    Pommier, Y.3
  • 38
    • 0030813607 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and colorectal cancer; evolving concepts of their chemopreventive actions
    • Shiff SJ and Rigas B (1997) Nonsteroidal anti-inflammatory drugs and colorectal cancer; evolving concepts of their chemopreventive actions. Gastroenterology 113: 1992-1998
    • (1997) Gastroenterology , vol.113 , pp. 1992-1998
    • Shiff, S.J.1    Rigas, B.2
  • 39
    • 0029115954 scopus 로고
    • Sulindae sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cells
    • Shiff SJ, Qiao L, Tsai LL and Rigas B (1995) Sulindae sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cells. J Clin Invest 96: 491-503
    • (1995) J Clin Invest , vol.96 , pp. 491-503
    • Shiff, S.J.1    Qiao, L.2    Tsai, L.L.3    Rigas, B.4
  • 40
    • 0030038519 scopus 로고    scopus 로고
    • Non steroidal antiinflammatory drugs inhibit the proliferation of colon adenocarcioma cells: Effects on cell cycle and apoptosis
    • Shiff SJ, Koutsos MI, Qiao L and Rigas B (1996) Non steroidal antiinflammatory drugs inhibit the proliferation of colon adenocarcioma cells: effects on cell cycle and apoptosis. Exp Cell Res 222: 179-188
    • (1996) Exp Cell Res , vol.222 , pp. 179-188
    • Shiff, S.J.1    Koutsos, M.I.2    Qiao, L.3    Rigas, B.4
  • 41
    • 0030628655 scopus 로고    scopus 로고
    • Colorectal cancer and nonsteroidal anti-inflammatory drugs
    • Smalley WE and DuBois RN (1997) Colorectal cancer and nonsteroidal anti-inflammatory drugs. Adv Pharmacol 39: 1-20
    • (1997) Adv Pharmacol , vol.39 , pp. 1-20
    • Smalley, W.E.1    DuBois, R.N.2
  • 42
    • 0024558198 scopus 로고
    • The cicosanoids and their biochemical mechanism of action
    • Smith WL (1989) The cicosanoids and their biochemical mechanism of action. Biochem J 259: 315-324
    • (1989) Biochem J , vol.259 , pp. 315-324
    • Smith, W.L.1
  • 43
    • 0032127342 scopus 로고    scopus 로고
    • Aspirin toxicity for human colonic tumor cells results from necrosis and is accompanied by cell cycle arrest
    • Subbegowda R and Frommel TO (1998) Aspirin toxicity for human colonic tumor cells results from necrosis and is accompanied by cell cycle arrest. Cancer Res 58: 2772-2776.
    • (1998) Cancer Res , vol.58 , pp. 2772-2776
    • Subbegowda, R.1    Frommel, T.O.2
  • 44
    • 0028803728 scopus 로고
    • Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
    • Tsujii M and Dubois RN (1995) Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 83: 493-501
    • (1995) Cell , vol.83 , pp. 493-501
    • Tsujii, M.1    Dubois, R.N.2
  • 45
    • 0003504049 scopus 로고    scopus 로고
    • Cyclooxygenase regulates angiogenesis induced by colon cancer cells
    • Tsujii M, Kawano S, Tsuji S, Sawaoka H, Hori M and DuBois RN (1998) Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 93: 705-716
    • (1998) Cell , vol.93 , pp. 705-716
    • Tsujii, M.1    Kawano, S.2    Tsuji, S.3    Sawaoka, H.4    Hori, M.5    DuBois, R.N.6
  • 46
    • 10544238107 scopus 로고    scopus 로고
    • Protease involvement in fodrin cleavage and phosphalidylserine exposure in apoptosis
    • Vanags DM, Porn-Ares MI, Coppola S, Burgess DH and Orrenius S (1996) Protease involvement in fodrin cleavage and phosphalidylserine exposure in apoptosis. J Biol Chem 271: 31075-31085
    • (1996) J Biol Chem , vol.271 , pp. 31075-31085
    • Vanags, D.M.1    Porn-Ares, M.I.2    Coppola, S.3    Burgess, D.H.4    Orrenius, S.5
  • 48
    • 0031985647 scopus 로고    scopus 로고
    • Annexin V-affinity assay: A review on an apoptosis detection system based on phosphatidylserine exposure
    • Van Engeland M, Nieland LJ, Ramackers FC, Schutte B and Reutelingsperger CP (1998) Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure. Cytometry 31: 1-9
    • (1998) Cytometry , vol.31 , pp. 1-9
    • Van Engeland, M.1    Nieland, L.J.2    Ramackers, F.C.3    Schutte, B.4    Reutelingsperger, C.P.5
  • 49
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
    • Vane JR (1971) Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature New Biol 231: 232-235
    • (1971) Nature New Biol , vol.231 , pp. 232-235
    • Vane, J.R.1
  • 50
    • 0029858387 scopus 로고    scopus 로고
    • TNF and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB in preventing TNF-α-induced cell death
    • Wang CY, Mayo MW and Baldwin AS (1996) TNF and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB in preventing TNF-α-induced cell death. Science 274: 784-787
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.Y.1    Mayo, M.W.2    Baldwin, A.S.3
  • 52
    • 0032487857 scopus 로고    scopus 로고
    • The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta
    • Yin MJ, Yamamoto Y and Gaynor RB (1998) The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Nature 396: 77-80
    • (1998) Nature , vol.396 , pp. 77-80
    • Yin, M.J.1    Yamamoto, Y.2    Gaynor, R.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.