Diclofenac attenuates Wnt/β-catenin signaling in colon cancer cells by activation of NF-κB

FEBS Letters

Volumn 579, Issue 20, 2005, Pages 4213-4218

  Cho, Munju ^a   Gwak, Jungsug ^a   Park, Seoyoung ^a   Won, Jaejoon ^b   Kim, Dong Eun ^c   Sung, Su Yea ^a   Cha, In June ^a   Tae, Kook Kim ^b   Shin, Jae Gook ^a   Oh, Sangtaek ^a  

^a Inje University   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^c Dong Eui University   (South Korea)

Author keywords

Colon cancer cell; Diclofenac; Nuclear factor B; Wnt catenin signaling

Indexed keywords

ACETYLSALICYLIC ACID; BETA CATENIN; DICLOFENAC; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SULINDAC; SYNAPTOTAGMIN; WNT PROTEIN;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; EMBRYO; GENE EXPRESSION REGULATION; GENE REPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTINEOPLASTIC AGENTS; BETA CATENIN; CALCIUM-BINDING PROTEINS; COLONIC NEOPLASMS; CYTOSKELETAL PROTEINS; DICLOFENAC; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE GLYCOPROTEINS; NERVE TISSUE PROTEINS; NF-KAPPA B; SIGNAL TRANSDUCTION; SYNAPTOTAGMIN I; SYNAPTOTAGMINS; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; WNT PROTEINS;

EID: 23744505379     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.06.049     Document Type: Article

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