Nitric oxide-donating aspirin induces apoptosis in human colon cancer cells through induction of oxidative stress

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 47, 2005, Pages 17207-17212

  Gao, Jianjun ^a   Liu, Xiaoping ^a   Rigas, Basil ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

Cell death; Chemoprevention; NO aspirin; Wnt signaling

Indexed keywords

ACETYLSALICYLIC ACID; BETA CATENIN; GLUTATHIONE; NITRIC OXIDE DONATING ASPIRIN; OXYGEN; PEROXIDE; PLAKOGLOBIN; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CELL JUNCTION; CELL KINETICS; CELL PROLIFERATION; CHEMOPROPHYLAXIS; COLON CANCER; COLON CARCINOGENESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG EFFECT; DRUG FORMULATION; DRUG MECHANISM; DRUG POTENCY; DRUG RELEASE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ADENOCARCINOMA; ADHERENS JUNCTIONS; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; ASPIRIN; BETA CATENIN; CASPASE 3; CASPASES; CELL LINE, TUMOR; COLONIC NEOPLASMS; CYCLIN D1; DOWN-REGULATION; GENES, APC; HUMANS; HYDROLYSIS; MICE; MICE, INBRED C57BL; NITRIC OXIDE DONORS; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 28044436484     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0506893102     Document Type: Article

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