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Volumn , Issue , 2013, Pages 5-26

Basic Principles of Bone Cell Biology

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EID: 84882756427     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-415784-2.00002-6     Document Type: Chapter
Times cited : (4)

References (225)
  • 1
    • 50949132946 scopus 로고    scopus 로고
    • Cell-cell communication in the osteoblast/osteocyte lineage
    • Civitelli R. Cell-cell communication in the osteoblast/osteocyte lineage. Arch Biochem Biophys 2008 May 15, 473(2):188-192.
    • (2008) Arch Biochem Biophys , vol.473 , Issue.2 , pp. 188-192
    • Civitelli, R.1
  • 2
    • 0001001573 scopus 로고
    • Bone cells: biochemical and biological studies after enzymatic isolation
    • Peck W.A., Birge S.J., Fedak S.A. Bone cells: biochemical and biological studies after enzymatic isolation. Science 1964 Dec 11, 146:1476-1477.
    • (1964) Science , vol.146 , pp. 1476-1477
    • Peck, W.A.1    Birge, S.J.2    Fedak, S.A.3
  • 3
    • 0017070871 scopus 로고
    • Biochemical characterization with parathormone and calcitonin of isolated bone cells: provisional identification of osteoclasts and osteoblasts
    • Luben R.A., Wong G.L., Cohn D.V. Biochemical characterization with parathormone and calcitonin of isolated bone cells: provisional identification of osteoclasts and osteoblasts. Endocrinology 1976 Aug, 99(2):526-534.
    • (1976) Endocrinology , vol.99 , Issue.2 , pp. 526-534
    • Luben, R.A.1    Wong, G.L.2    Cohn, D.V.3
  • 4
    • 0020562941 scopus 로고
    • Morphological and biochemical characterization of four clonal osteogenic sarcoma cell lines of rat origin
    • Partridge N.C., Alcorn D., Michelangeli V.P., Ryan G., Martin T.J. Morphological and biochemical characterization of four clonal osteogenic sarcoma cell lines of rat origin. Cancer Res 1983 Sep, 43(9):4308-4314.
    • (1983) Cancer Res , vol.43 , Issue.9 , pp. 4308-4314
    • Partridge, N.C.1    Alcorn, D.2    Michelangeli, V.P.3    Ryan, G.4    Martin, T.J.5
  • 5
    • 0018926608 scopus 로고
    • Parathyroid hormone-responsive clonal cell lines from rat osteosarcoma
    • Majeska R.J., Rodan S.B., Rodan G.A. Parathyroid hormone-responsive clonal cell lines from rat osteosarcoma. Endocrinology 1980 Nov, 107(5):1494-1503.
    • (1980) Endocrinology , vol.107 , Issue.5 , pp. 1494-1503
    • Majeska, R.J.1    Rodan, S.B.2    Rodan, G.A.3
  • 6
    • 0018097803 scopus 로고
    • Rat osteogenic sarcoma cells: comparison of the effects of prostaglandins E1, E2, I2 (prostacyclin), 6-keto F1alpha and thromboxane B2 on cyclic AMP production and adenylate cyclase activity
    • Crawford A., Atkins D., Martin T.J. Rat osteogenic sarcoma cells: comparison of the effects of prostaglandins E1, E2, I2 (prostacyclin), 6-keto F1alpha and thromboxane B2 on cyclic AMP production and adenylate cyclase activity. Biochem Biophys Res Commun 1978 Jun 29, 82(4):1195-1201.
    • (1978) Biochem Biophys Res Commun , vol.82 , Issue.4 , pp. 1195-1201
    • Crawford, A.1    Atkins, D.2    Martin, T.J.3
  • 7
    • 0019365043 scopus 로고
    • Functional properties of hormonally responsive cultured normal and malignant rat osteoblastic cells
    • Partridge N.C., Alcorn D., Michelangeli V.P., Kemp B.E., Ryan G.B., Martin T.J. Functional properties of hormonally responsive cultured normal and malignant rat osteoblastic cells. Endocrinology 1981 Jan, 108(1):213-219.
    • (1981) Endocrinology , vol.108 , Issue.1 , pp. 213-219
    • Partridge, N.C.1    Alcorn, D.2    Michelangeli, V.P.3    Kemp, B.E.4    Ryan, G.B.5    Martin, T.J.6
  • 8
    • 0020156953 scopus 로고
    • Activity ratio measurements reflect intracellular activation of adenosine 3′,5′-monophosphate-dependent protein kinase in osteoblasts
    • Partridge N.C., Kemp B.E., Livesey S.A., Martin T.J. Activity ratio measurements reflect intracellular activation of adenosine 3′,5′-monophosphate-dependent protein kinase in osteoblasts. Endocrinology 1982 Jul, 111(1):178-183.
    • (1982) Endocrinology , vol.111 , Issue.1 , pp. 178-183
    • Partridge, N.C.1    Kemp, B.E.2    Livesey, S.A.3    Martin, T.J.4
  • 9
    • 0020678843 scopus 로고
    • In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria
    • Sudo H., Kodama H.A., Amagai Y., Yamamoto S., Kasai S. In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria. J Cell Biol 1983 Jan, 96(1):191-198.
    • (1983) J Cell Biol , vol.96 , Issue.1 , pp. 191-198
    • Sudo, H.1    Kodama, H.A.2    Amagai, Y.3    Yamamoto, S.4    Kasai, S.5
  • 11
    • 0024779001 scopus 로고
    • The onset and progression of osteoblast differentiation is functionally related to cellular proliferation
    • Stein G.S., Lian J.B., Gerstenfeld L.G., Shalhoub V., Aronow M., Owen T., et al. The onset and progression of osteoblast differentiation is functionally related to cellular proliferation. Connect Tissue Res 1989, 20(1-4):3-13.
    • (1989) Connect Tissue Res , vol.20 , Issue.1-4 , pp. 3-13
    • Stein, G.S.1    Lian, J.B.2    Gerstenfeld, L.G.3    Shalhoub, V.4    Aronow, M.5    Owen, T.6
  • 12
    • 41549139755 scopus 로고    scopus 로고
    • Mesenchymal stem cells: revisiting history, concepts, and assays
    • Bianco P., Robey P.G., Simmons P.J. Mesenchymal stem cells: revisiting history, concepts, and assays. Cell Stem Cell 2008 Apr 10, 2(4):313-319.
    • (2008) Cell Stem Cell , vol.2 , Issue.4 , pp. 313-319
    • Bianco, P.1    Robey, P.G.2    Simmons, P.J.3
  • 13
    • 77957853504 scopus 로고    scopus 로고
    • "Mesenchymal" stem cells in human bone marrow (skeletal stem cells): a critical discussion of their nature, identity, and significance in incurable skeletal disease
    • Bianco P., Robey P.G., Saggio I., Riminucci M. "Mesenchymal" stem cells in human bone marrow (skeletal stem cells): a critical discussion of their nature, identity, and significance in incurable skeletal disease. Hum Gene Ther 2010 Sep, 21(9):1057-1066.
    • (2010) Hum Gene Ther , vol.21 , Issue.9 , pp. 1057-1066
    • Bianco, P.1    Robey, P.G.2    Saggio, I.3    Riminucci, M.4
  • 14
    • 0017103248 scopus 로고
    • Precursor cells of mechanocytes
    • Friedenstein A.J. Precursor cells of mechanocytes. Int Rev Cytol 1976, 47:327-359.
    • (1976) Int Rev Cytol , vol.47 , pp. 327-359
    • Friedenstein, A.J.1
  • 15
    • 0021149666 scopus 로고
    • Assessment of an in vivo diffusion chamber method as a quantitative assay for osteogenesis
    • Bab I., Ashton B.A., Syftestad G.T., Owen M.E. Assessment of an in vivo diffusion chamber method as a quantitative assay for osteogenesis. Calcif Tissue Int 1984 Jan, 36(1):77-82.
    • (1984) Calcif Tissue Int , vol.36 , Issue.1 , pp. 77-82
    • Bab, I.1    Ashton, B.A.2    Syftestad, G.T.3    Owen, M.E.4
  • 17
    • 0000670671 scopus 로고
    • Osteogenic stem cells
    • Elsevier, Amsterdam, J.N.M. Heerschje, J.A. Kanis (Eds.)
    • Friedenstein A.J. Osteogenic stem cells. Bone and Mineral Research 1990, 243-272. Elsevier, Amsterdam. J.N.M. Heerschje, J.A. Kanis (Eds.).
    • (1990) Bone and Mineral Research , pp. 243-272
    • Friedenstein, A.J.1
  • 18
    • 34547107887 scopus 로고    scopus 로고
    • Greater bone formation of Y2 knockout mice is associated with increased osteoprogenitor numbers and altered Y1 receptor expression
    • Lundberg P., Allison S.J., Lee N.J., Baldock P.A., Brouard N., Rost S., et al. Greater bone formation of Y2 knockout mice is associated with increased osteoprogenitor numbers and altered Y1 receptor expression. J Biol Chem 2007 Jun 29, 282(26):19082-19091.
    • (2007) J Biol Chem , vol.282 , Issue.26 , pp. 19082-19091
    • Lundberg, P.1    Allison, S.J.2    Lee, N.J.3    Baldock, P.A.4    Brouard, N.5    Rost, S.6
  • 19
    • 21644486143 scopus 로고    scopus 로고
    • Expression profile of osteoblast lineage at defined stages of differentiation
    • Kalajzic I., Staal A., Yang W.P., Wu Y., Johnson S.E., Feyen J.H., et al. Expression profile of osteoblast lineage at defined stages of differentiation. J Biol Chem 2005 Jul 1, 280(26):24618-24626.
    • (2005) J Biol Chem , vol.280 , Issue.26 , pp. 24618-24626
    • Kalajzic, I.1    Staal, A.2    Yang, W.P.3    Wu, Y.4    Johnson, S.E.5    Feyen, J.H.6
  • 20
    • 68849117424 scopus 로고    scopus 로고
    • Identification of differentially expressed genes between osteoblasts and osteocytes
    • Paic F., Igwe J.C., Nori R., Kronenberg M.S., Franceschetti T., Harrington P., et al. Identification of differentially expressed genes between osteoblasts and osteocytes. Bone 2009 Oct, 45(4):682-692.
    • (2009) Bone , vol.45 , Issue.4 , pp. 682-692
    • Paic, F.1    Igwe, J.C.2    Nori, R.3    Kronenberg, M.S.4    Franceschetti, T.5    Harrington, P.6
  • 21
    • 38649092398 scopus 로고    scopus 로고
    • Skeletal stem/osteoprogenitor cells: current concepts, alternate hypotheses, and relationship to the bone remodeling compartment
    • Modder U.I., Khosla S. Skeletal stem/osteoprogenitor cells: current concepts, alternate hypotheses, and relationship to the bone remodeling compartment. J Cell Biochem 2008 Feb 1, 103(2):393-400.
    • (2008) J Cell Biochem , vol.103 , Issue.2 , pp. 393-400
    • Modder, U.I.1    Khosla, S.2
  • 22
    • 38349073636 scopus 로고    scopus 로고
    • Circulating bone marrow-derived osteoblast progenitor cells are recruited to the bone-forming site by the CXCR4/stromal cell-derived factor-1 pathway
    • Otsuru S., Tamai K., Yamazaki T., Yoshikawa H., Kaneda Y. Circulating bone marrow-derived osteoblast progenitor cells are recruited to the bone-forming site by the CXCR4/stromal cell-derived factor-1 pathway. Stem Cells 2008 Jan, 26(1):223-234.
    • (2008) Stem Cells , vol.26 , Issue.1 , pp. 223-234
    • Otsuru, S.1    Tamai, K.2    Yamazaki, T.3    Yoshikawa, H.4    Kaneda, Y.5
  • 24
    • 49149128079 scopus 로고    scopus 로고
    • Use of an alpha-smooth muscle actin GFP reporter to identify an osteoprogenitor population
    • Kalajzic Z., Li H., Wang L.P., Jiang X., Lamothe K., Adams D.J., et al. Use of an alpha-smooth muscle actin GFP reporter to identify an osteoprogenitor population. Bone 2008 Sep, 43(3):501-510.
    • (2008) Bone , vol.43 , Issue.3 , pp. 501-510
    • Kalajzic, Z.1    Li, H.2    Wang, L.P.3    Jiang, X.4    Lamothe, K.5    Adams, D.J.6
  • 25
  • 26
    • 79958279325 scopus 로고    scopus 로고
    • In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche
    • Fujisaki J., Wu J., Carlson A.L., Silberstein L., Putheti P., Larocca R., et al. In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche. Nature 2011 Jun 9, 474(7350):216-219.
    • (2011) Nature , vol.474 , Issue.7350 , pp. 216-219
    • Fujisaki, J.1    Wu, J.2    Carlson, A.L.3    Silberstein, L.4    Putheti, P.5    Larocca, R.6
  • 27
    • 0025741349 scopus 로고
    • Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1
    • Simmons P.J., Torok-Storb B. Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1. Blood 1991 Jul 1, 78(1):55-62.
    • (1991) Blood , vol.78 , Issue.1 , pp. 55-62
    • Simmons, P.J.1    Torok-Storb, B.2
  • 28
    • 0032892727 scopus 로고    scopus 로고
    • Differential cell surface expression of the STRO-1 and alkaline phosphatase antigens on discrete developmental stages in primary cultures of human bone cells
    • Gronthos S., Zannettino A.C., Graves S.E., Ohta S., Hay S.J., Simmons P.J. Differential cell surface expression of the STRO-1 and alkaline phosphatase antigens on discrete developmental stages in primary cultures of human bone cells. J Bone Miner Res 1999 Jan, 14(1):47-56.
    • (1999) J Bone Miner Res , vol.14 , Issue.1 , pp. 47-56
    • Gronthos, S.1    Zannettino, A.C.2    Graves, S.E.3    Ohta, S.4    Hay, S.J.5    Simmons, P.J.6
  • 29
    • 0032809980 scopus 로고    scopus 로고
    • Further characterization of cells expressing STRO-1 in cultures of adult human bone marrow stromal cells
    • Stewart K., Walsh S., Screen J., Jefferiss C.M., Chainey J., Jordan G.R., et al. Further characterization of cells expressing STRO-1 in cultures of adult human bone marrow stromal cells. J Bone Miner Res 1999 Aug, 14(8):1345-1356.
    • (1999) J Bone Miner Res , vol.14 , Issue.8 , pp. 1345-1356
    • Stewart, K.1    Walsh, S.2    Screen, J.3    Jefferiss, C.M.4    Chainey, J.5    Jordan, G.R.6
  • 30
    • 0035236997 scopus 로고    scopus 로고
    • Regulation of osteoblast formation and function
    • Aubin J.E. Regulation of osteoblast formation and function. Rev Endocr Metab Disord 2001 Jan, 2(1):81-94.
    • (2001) Rev Endocr Metab Disord , vol.2 , Issue.1 , pp. 81-94
    • Aubin, J.E.1
  • 31
    • 0032323828 scopus 로고    scopus 로고
    • Advances in the osteoblast lineage
    • Aubin J.E. Advances in the osteoblast lineage. Biochem Cell Biol 1998, 76(6):899-910.
    • (1998) Biochem Cell Biol , vol.76 , Issue.6 , pp. 899-910
    • Aubin, J.E.1
  • 32
    • 0027321842 scopus 로고
    • Molecular mechanisms mediating proliferation/differentiation interrelationships during progressive development of the osteoblast phenotype
    • Stein G.S., Lian J.B. Molecular mechanisms mediating proliferation/differentiation interrelationships during progressive development of the osteoblast phenotype. Endocr Rev 1993 Aug, 14(4):424-442.
    • (1993) Endocr Rev , vol.14 , Issue.4 , pp. 424-442
    • Stein, G.S.1    Lian, J.B.2
  • 33
    • 0034984151 scopus 로고    scopus 로고
    • Minireview: transcriptional control of osteoblast differentiation
    • Karsenty G. Minireview: transcriptional control of osteoblast differentiation. Endocrinology 2001 Jul, 142(7):2731-2733.
    • (2001) Endocrinology , vol.142 , Issue.7 , pp. 2731-2733
    • Karsenty, G.1
  • 35
    • 0033560784 scopus 로고    scopus 로고
    • A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development
    • Ducy P., Starbuck M., Priemel M., Shen J., Pinero G., Geoffroy V., et al. A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development. Genes Dev 1999 Apr 15, 13(8):1025-1036.
    • (1999) Genes Dev , vol.13 , Issue.8 , pp. 1025-1036
    • Ducy, P.1    Starbuck, M.2    Priemel, M.3    Shen, J.4    Pinero, G.5    Geoffroy, V.6
  • 36
    • 0035965326 scopus 로고    scopus 로고
    • Stimulation of osteoprotegerin (OPG) gene expression by transforming growth factor-beta (TGF-beta). Mapping of the OPG promoter region that mediates TGF-beta effects
    • Thirunavukkarasu K., Miles R.R., Halladay D.L., Yang X., Galvin R.J., Chandrasekhar S., et al. Stimulation of osteoprotegerin (OPG) gene expression by transforming growth factor-beta (TGF-beta). Mapping of the OPG promoter region that mediates TGF-beta effects. J Biol Chem 2001 Sep 28, 276(39):36241-36250.
    • (2001) J Biol Chem , vol.276 , Issue.39 , pp. 36241-36250
    • Thirunavukkarasu, K.1    Miles, R.R.2    Halladay, D.L.3    Yang, X.4    Galvin, R.J.5    Chandrasekhar, S.6
  • 37
    • 0037059614 scopus 로고    scopus 로고
    • The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation
    • Nakashima K., Zhou X., Kunkel G., Zhang Z., Deng J.M., Behringer R.R., et al. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 2002 Jan 11, 108(1):17-29.
    • (2002) Cell , vol.108 , Issue.1 , pp. 17-29
    • Nakashima, K.1    Zhou, X.2    Kunkel, G.3    Zhang, Z.4    Deng, J.M.5    Behringer, R.R.6
  • 38
    • 11144357428 scopus 로고    scopus 로고
    • ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry syndrome
    • Yang X., Matsuda K., Bialek P., Jacquot S., Masuoka H.C., Schinke T., et al. ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry syndrome. Cell 2004 Apr 30, 117(3):387-398.
    • (2004) Cell , vol.117 , Issue.3 , pp. 387-398
    • Yang, X.1    Matsuda, K.2    Bialek, P.3    Jacquot, S.4    Masuoka, H.C.5    Schinke, T.6
  • 39
    • 0033624587 scopus 로고    scopus 로고
    • Overexpression of DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis
    • Sabatakos G., Sims N.A., Chen J., Aoki K., Kelz M.B., Amling M., et al. Overexpression of DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis. Nat Med 2000 Sep, 6(9):985-990.
    • (2000) Nat Med , vol.6 , Issue.9 , pp. 985-990
    • Sabatakos, G.1    Sims, N.A.2    Chen, J.3    Aoki, K.4    Kelz, M.B.5    Amling, M.6
  • 40
    • 0034766416 scopus 로고    scopus 로고
    • Regulation of the activity of the transcription factor Runx2 by two homeobox proteins, Msx2 and Dlx5
    • Shirakabe K., Terasawa K., Miyama K., Shibuya H., Nishida E. Regulation of the activity of the transcription factor Runx2 by two homeobox proteins, Msx2 and Dlx5. Genes Cells 2001 Oct, 6(10):851-856.
    • (2001) Genes Cells , vol.6 , Issue.10 , pp. 851-856
    • Shirakabe, K.1    Terasawa, K.2    Miyama, K.3    Shibuya, H.4    Nishida, E.5
  • 42
    • 0031021336 scopus 로고    scopus 로고
    • Mutations in TWIST, a basic helix-loop-helix transcription factor, in Saethre-Chotzen syndrome
    • Howard T.D., Paznekas W.A., Green E.D., Chiang L.C., Ma N., Ortiz de Luna R.I., et al. Mutations in TWIST, a basic helix-loop-helix transcription factor, in Saethre-Chotzen syndrome. Nat Genet 1997 Jan, 15(1):36-41.
    • (1997) Nat Genet , vol.15 , Issue.1 , pp. 36-41
    • Howard, T.D.1    Paznekas, W.A.2    Green, E.D.3    Chiang, L.C.4    Ma, N.5    Ortiz de Luna, R.I.6
  • 43
    • 0037059765 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression
    • Gutierrez S., Javed A., Tennant D.K., van Rees M., Montecino M., Stein G.S., et al. CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression. J Biol Chem 2002 Jan 11, 277(2):1316-1323.
    • (2002) J Biol Chem , vol.277 , Issue.2 , pp. 1316-1323
    • Gutierrez, S.1    Javed, A.2    Tennant, D.K.3    van Rees, M.4    Montecino, M.5    Stein, G.S.6
  • 44
    • 61849130657 scopus 로고    scopus 로고
    • Zfp521 antagonizes Runx2, delays osteoblast differentiation in vitro, and promotes bone formation in vivo
    • Wu M., Hesse E., Morvan F., Zhang J.P., Correa D., Rowe G.C., et al. Zfp521 antagonizes Runx2, delays osteoblast differentiation in vitro, and promotes bone formation in vivo. Bone 2009 Apr, 44(4):528-536.
    • (2009) Bone , vol.44 , Issue.4 , pp. 528-536
    • Wu, M.1    Hesse, E.2    Morvan, F.3    Zhang, J.P.4    Correa, D.5    Rowe, G.C.6
  • 45
    • 0033213637 scopus 로고    scopus 로고
    • PPAR gamma is required for placental, cardiac, and adipose tissue development
    • Barak Y., Nelson M.C., Ong E.S., Jones Y.Z., Ruiz-Lozano P., Chien K.R., et al. PPAR gamma is required for placental, cardiac, and adipose tissue development. Mol Cell 1999 Oct, 4(4):585-595.
    • (1999) Mol Cell , vol.4 , Issue.4 , pp. 585-595
    • Barak, Y.1    Nelson, M.C.2    Ong, E.S.3    Jones, Y.Z.4    Ruiz-Lozano, P.5    Chien, K.R.6
  • 46
    • 0031435337 scopus 로고    scopus 로고
    • Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene
    • Tanaka T., Yoshida N., Kishimoto T., Akira S. Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene. EMBO J 1997 Dec 15, 16(24):7432-7443.
    • (1997) EMBO J , vol.16 , Issue.24 , pp. 7432-7443
    • Tanaka, T.1    Yoshida, N.2    Kishimoto, T.3    Akira, S.4
  • 47
    • 79953000714 scopus 로고    scopus 로고
    • Zinc finger protein 467 is a novel regulator of osteoblast and adipocyte commitment
    • Quach J.M., Walker E.C., Allan E., Solano M., Yokoyama A., Kato S., et al. Zinc finger protein 467 is a novel regulator of osteoblast and adipocyte commitment. J Biol Chem 2011 Feb 11, 286(6):4186-4198.
    • (2011) J Biol Chem , vol.286 , Issue.6 , pp. 4186-4198
    • Quach, J.M.1    Walker, E.C.2    Allan, E.3    Solano, M.4    Yokoyama, A.5    Kato, S.6
  • 48
    • 0034842784 scopus 로고    scopus 로고
    • Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis
    • Justesen J., Stenderup K., Ebbesen E.N., Mosekilde L., Steiniche T., Kassem M. Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis. Biogerontology 2001, 2(3):165-171.
    • (2001) Biogerontology , vol.2 , Issue.3 , pp. 165-171
    • Justesen, J.1    Stenderup, K.2    Ebbesen, E.N.3    Mosekilde, L.4    Steiniche, T.5    Kassem, M.6
  • 49
    • 0025129055 scopus 로고
    • Bone marrow fat content in relation to bone remodeling and serum chemistry in intact and ovariectomized dogs
    • Martin R.B., Chow B.D., Lucas P.A. Bone marrow fat content in relation to bone remodeling and serum chemistry in intact and ovariectomized dogs. Calcif Tissue Int 1990 Mar, 46(3):189-194.
    • (1990) Calcif Tissue Int , vol.46 , Issue.3 , pp. 189-194
    • Martin, R.B.1    Chow, B.D.2    Lucas, P.A.3
  • 50
    • 0036128727 scopus 로고    scopus 로고
    • Transforming growth factor beta2 inhibits adipocyte differentiation induced by skeletal unloading in rat bone marrow stroma
    • Ahdjoudj S., Lasmoles F., Holy X., Zerath E., Marie P.J. Transforming growth factor beta2 inhibits adipocyte differentiation induced by skeletal unloading in rat bone marrow stroma. J Bone Miner Res 2002 Apr, 17(4):668-677.
    • (2002) J Bone Miner Res , vol.17 , Issue.4 , pp. 668-677
    • Ahdjoudj, S.1    Lasmoles, F.2    Holy, X.3    Zerath, E.4    Marie, P.J.5
  • 51
    • 56749103188 scopus 로고    scopus 로고
    • Cardiotrophin-1 is an osteoclast-derived stimulus of bone formation required for normal bone remodeling
    • Walker E., McGregor N., Poulton I., Pompolo S., Allan E., Quinn J., et al. Cardiotrophin-1 is an osteoclast-derived stimulus of bone formation required for normal bone remodeling. J Bone Miner Res 2008 Dec, 23:2025-2032.
    • (2008) J Bone Miner Res , vol.23 , pp. 2025-2032
    • Walker, E.1    McGregor, N.2    Poulton, I.3    Pompolo, S.4    Allan, E.5    Quinn, J.6
  • 52
    • 76649121173 scopus 로고    scopus 로고
    • Oncostatin M promotes bone formation independently of resorption through the leukemia inhibitory factor receptor
    • in press
    • Walker E.C., McGregor N.E., Poulton I.J., Solano M., Pompolo S., Fernandes T.J., et al. Oncostatin M promotes bone formation independently of resorption through the leukemia inhibitory factor receptor. J Clin Invest 2010, in press.
    • (2010) J Clin Invest
    • Walker, E.C.1    McGregor, N.E.2    Poulton, I.J.3    Solano, M.4    Pompolo, S.5    Fernandes, T.J.6
  • 53
    • 0037118285 scopus 로고    scopus 로고
    • High bone density due to a mutation in LDL-receptor-related protein 5
    • Boyden L.M., Mao J., Belsky J., Mitzner L., Farhi A., Mitnick M.A., et al. High bone density due to a mutation in LDL-receptor-related protein 5. N Engl J Med 2002 May 16, 346(20):1513-1521.
    • (2002) N Engl J Med , vol.346 , Issue.20 , pp. 1513-1521
    • Boyden, L.M.1    Mao, J.2    Belsky, J.3    Mitzner, L.4    Farhi, A.5    Mitnick, M.A.6
  • 54
    • 18044386744 scopus 로고    scopus 로고
    • LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
    • Gong Y., Slee R.B., Fukai N., Rawadi G., Roman-Roman S., Reginato A.M., et al. LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell 2001 Nov 16, 107(4):513-523.
    • (2001) Cell , vol.107 , Issue.4 , pp. 513-523
    • Gong, Y.1    Slee, R.B.2    Fukai, N.3    Rawadi, G.4    Roman-Roman, S.5    Reginato, A.M.6
  • 55
    • 0142241118 scopus 로고    scopus 로고
    • BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a Wnt autocrine loop
    • Rawadi G., Vayssiere B., Dunn F., Baron R., Roman-Roman S. BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a Wnt autocrine loop. J Bone Miner Res 2003 Oct, 18(10):1842-1853.
    • (2003) J Bone Miner Res , vol.18 , Issue.10 , pp. 1842-1853
    • Rawadi, G.1    Vayssiere, B.2    Dunn, F.3    Baron, R.4    Roman-Roman, S.5
  • 56
    • 0037092049 scopus 로고    scopus 로고
    • Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor
    • Kato M., Patel M.S., Levasseur R., Lobov I., Chang B.H., Glass D.A., et al. Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor. J Cell Biol 2002 Apr 15, 157(2):303-314.
    • (2002) J Cell Biol , vol.157 , Issue.2 , pp. 303-314
    • Kato, M.1    Patel, M.S.2    Levasseur, R.3    Lobov, I.4    Chang, B.H.5    Glass, D.A.6
  • 58
    • 34250848174 scopus 로고    scopus 로고
    • In vivo analysis of Wnt signaling in bone
    • Glass D.A., Karsenty G. In vivo analysis of Wnt signaling in bone. Endocrinology 2007 Jun, 148(6):2630-2634.
    • (2007) Endocrinology , vol.148 , Issue.6 , pp. 2630-2634
    • Glass, D.A.1    Karsenty, G.2
  • 59
  • 60
    • 33646414025 scopus 로고    scopus 로고
    • Orally bioavailable GSK-3alpha/beta dual inhibitor increases markers of cellular differentiation in vitro and bone mass in vivo
    • Kulkarni N.H., Onyia J.E., Zeng Q., Tian X., Liu M., Halladay D.L., et al. Orally bioavailable GSK-3alpha/beta dual inhibitor increases markers of cellular differentiation in vitro and bone mass in vivo. J Bone Miner Res 2006 Jun, 21(6):910-920.
    • (2006) J Bone Miner Res , vol.21 , Issue.6 , pp. 910-920
    • Kulkarni, N.H.1    Onyia, J.E.2    Zeng, Q.3    Tian, X.4    Liu, M.5    Halladay, D.L.6
  • 61
    • 20244373613 scopus 로고    scopus 로고
    • Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation
    • Glass D.A., Bialek P., Ahn J.D., Starbuck M., Patel M.S., Clevers H., et al. Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell 2005 May, 8(5):751-764.
    • (2005) Dev Cell , vol.8 , Issue.5 , pp. 751-764
    • Glass, D.A.1    Bialek, P.2    Ahn, J.D.3    Starbuck, M.4    Patel, M.S.5    Clevers, H.6
  • 62
    • 77953407742 scopus 로고    scopus 로고
    • Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis
    • Kramer I., Halleux C., Keller H., Pegurri M., Gooi J.H., Weber P.B., et al. Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis. Mol Cell Biol 2010 Jun, 30(12):3071-3085.
    • (2010) Mol Cell Biol , vol.30 , Issue.12 , pp. 3071-3085
    • Kramer, I.1    Halleux, C.2    Keller, H.3    Pegurri, M.4    Gooi, J.H.5    Weber, P.B.6
  • 63
    • 52949105706 scopus 로고    scopus 로고
    • Lrp6 hypomorphic mutation affects bone mass through bone resorption in mice and impairs interaction with Mesd
    • Kubota T., Michigami T., Sakaguchi N., Kokubu C., Suzuki A., Namba N., et al. Lrp6 hypomorphic mutation affects bone mass through bone resorption in mice and impairs interaction with Mesd. J Bone Miner Res 2008 Oct, 23(10):1661-1671.
    • (2008) J Bone Miner Res , vol.23 , Issue.10 , pp. 1661-1671
    • Kubota, T.1    Michigami, T.2    Sakaguchi, N.3    Kokubu, C.4    Suzuki, A.5    Namba, N.6
  • 65
    • 56349162283 scopus 로고    scopus 로고
    • Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum
    • Yadav V.K., Ryu J.H., Suda N., Tanaka K.F., Gingrich J.A., Schutz G., et al. Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum. Cell 2008 Nov 28, 135(5):825-837.
    • (2008) Cell , vol.135 , Issue.5 , pp. 825-837
    • Yadav, V.K.1    Ryu, J.H.2    Suda, N.3    Tanaka, K.F.4    Gingrich, J.A.5    Schutz, G.6
  • 66
    • 77949270283 scopus 로고    scopus 로고
    • Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis
    • Yadav V.K., Balaji S., Suresh P.S., Liu X.S., Lu X., Li Z., et al. Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis. Nat Med 2010 Mar, 16(3):308-312.
    • (2010) Nat Med , vol.16 , Issue.3 , pp. 308-312
    • Yadav, V.K.1    Balaji, S.2    Suresh, P.S.3    Liu, X.S.4    Lu, X.5    Li, Z.6
  • 67
  • 69
    • 79251493453 scopus 로고    scopus 로고
    • The amazing osteocyte
    • Bonewald L.F. The amazing osteocyte. J Bone Miner Res 2011 Feb, 26(2):229-238.
    • (2011) J Bone Miner Res , vol.26 , Issue.2 , pp. 229-238
    • Bonewald, L.F.1
  • 70
    • 20944440742 scopus 로고    scopus 로고
    • The metalloproteinase MT1-MMP is required for normal development and maintenance of osteocyte processes in bone
    • Holmbeck K., Bianco P., Pidoux I., Inoue S., Billinghurst R.C., Wu W., et al. The metalloproteinase MT1-MMP is required for normal development and maintenance of osteocyte processes in bone. J Cell Sci 2005 Jan 1, 118(Pt 1):147-156.
    • (2005) J Cell Sci , vol.118 , Issue.PT 1 , pp. 147-156
    • Holmbeck, K.1    Bianco, P.2    Pidoux, I.3    Inoue, S.4    Billinghurst, R.C.5    Wu, W.6
  • 71
    • 0029881460 scopus 로고    scopus 로고
    • Characterization and cloning of the E11 antigen, a marker expressed by rat osteoblasts and osteocytes
    • Wetterwald A., Hoffstetter W., Cecchini M.G., Lanske B., Wagner C., Fleisch H., et al. Characterization and cloning of the E11 antigen, a marker expressed by rat osteoblasts and osteocytes. Bone 1996 Feb, 18(2):125-132.
    • (1996) Bone , vol.18 , Issue.2 , pp. 125-132
    • Wetterwald, A.1    Hoffstetter, W.2    Cecchini, M.G.3    Lanske, B.4    Wagner, C.5    Fleisch, H.6
  • 72
    • 22244474640 scopus 로고    scopus 로고
    • Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease
    • Loots G.G., Kneissel M., Keller H., Baptist M., Chang J., Collette N.M., et al. Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease. Genome Res 2005 Jul, 15(7):928-935.
    • (2005) Genome Res , vol.15 , Issue.7 , pp. 928-935
    • Loots, G.G.1    Kneissel, M.2    Keller, H.3    Baptist, M.4    Chang, J.5    Collette, N.M.6
  • 73
    • 18244403197 scopus 로고    scopus 로고
    • Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease
    • Balemans W., Patel N., Ebeling M., Van Hul E., Wuyts W., Lacza C., et al. Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease. J Med Genet 2002 Feb, 39(2):91-97.
    • (2002) J Med Genet , vol.39 , Issue.2 , pp. 91-97
    • Balemans, W.1    Patel, N.2    Ebeling, M.3    Van Hul, E.4    Wuyts, W.5    Lacza, C.6
  • 74
    • 0035282968 scopus 로고    scopus 로고
    • Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)
    • Balemans W., Ebeling M., Patel N., Van Hul E., Olson P., Dioszegi M., et al. Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST). Hum Mol Genet 2001 Mar 1, 10(5):537-543.
    • (2001) Hum Mol Genet , vol.10 , Issue.5 , pp. 537-543
    • Balemans, W.1    Ebeling, M.2    Patel, N.3    Van Hul, E.4    Olson, P.5    Dioszegi, M.6
  • 75
    • 65549152230 scopus 로고    scopus 로고
    • Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis
    • Li X., Ominsky M.S., Warmington K.S., Morony S., Gong J., Cao J., et al. Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis. J Bone Miner Res 2009 Apr, 24(4):578-588.
    • (2009) J Bone Miner Res , vol.24 , Issue.4 , pp. 578-588
    • Li, X.1    Ominsky, M.S.2    Warmington, K.S.3    Morony, S.4    Gong, J.5    Cao, J.6
  • 76
    • 70349920691 scopus 로고    scopus 로고
    • A short treatment with an antibody to sclerostin can inhibit bone loss in an ongoing model of colitis
    • Eddleston A., Marenzana M., Moore A.R., Stephens P., Muzylak M., Marshall D., et al. A short treatment with an antibody to sclerostin can inhibit bone loss in an ongoing model of colitis. J Bone Miner Res 2009 Oct, 24(10):1662-1671.
    • (2009) J Bone Miner Res , vol.24 , Issue.10 , pp. 1662-1671
    • Eddleston, A.1    Marenzana, M.2    Moore, A.R.3    Stephens, P.4    Muzylak, M.5    Marshall, D.6
  • 77
    • 78650958526 scopus 로고    scopus 로고
    • Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody
    • Padhi D., Jang G., Stouch B., Fang L., Posvar E. Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody. J Bone Miner Res 2011 Jan, 26(1):19-26.
    • (2011) J Bone Miner Res , vol.26 , Issue.1 , pp. 19-26
    • Padhi, D.1    Jang, G.2    Stouch, B.3    Fang, L.4    Posvar, E.5
  • 79
    • 21844467220 scopus 로고    scopus 로고
    • SOST is a target gene for PTH in bone
    • Keller H., Kneissel M. SOST is a target gene for PTH in bone. Bone 2005 Aug, 37(2):148-158.
    • (2005) Bone , vol.37 , Issue.2 , pp. 148-158
    • Keller, H.1    Kneissel, M.2
  • 80
    • 79952742823 scopus 로고    scopus 로고
    • Prostaglandin E2 signals through PTGER2 to regulate sclerostin expression
    • Genetos D.C., Yellowley C.E., Loots G.G. Prostaglandin E2 signals through PTGER2 to regulate sclerostin expression. PLoS ONE 2011, 6(3):e17772.
    • (2011) PLoS ONE , vol.6 , Issue.3
    • Genetos, D.C.1    Yellowley, C.E.2    Loots, G.G.3
  • 82
    • 79953701946 scopus 로고    scopus 로고
    • Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses
    • Powell W.F., Barry K.J., Tulum I., Kobayashi T., Harris S.E., Bringhurst F.R., et al. Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses. J Endocrinol 2011 Apr, 209(1):21-32.
    • (2011) J Endocrinol , vol.209 , Issue.1 , pp. 21-32
    • Powell, W.F.1    Barry, K.J.2    Tulum, I.3    Kobayashi, T.4    Harris, S.E.5    Bringhurst, F.R.6
  • 83
    • 0031442990 scopus 로고    scopus 로고
    • Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide
    • Schipani E., Lanske B., Hunzelman J., Luz A., Kovacs C.S., Lee K., et al. Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide. Proc Natl Acad Sci USA 1997 Dec 9, 94(25):13689-13694.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.25 , pp. 13689-13694
    • Schipani, E.1    Lanske, B.2    Hunzelman, J.3    Luz, A.4    Kovacs, C.S.5    Lee, K.6
  • 84
    • 27844517983 scopus 로고    scopus 로고
    • Sympathetic nervous system does not mediate the load-induced cortical new bone formation
    • de Souza R.L., Pitsillides A.A., Lanyon L.E., Skerry T.M., Chenu C. Sympathetic nervous system does not mediate the load-induced cortical new bone formation. J Bone Miner Res 2005 Dec, 20(12):2159-2168.
    • (2005) J Bone Miner Res , vol.20 , Issue.12 , pp. 2159-2168
    • de Souza, R.L.1    Pitsillides, A.A.2    Lanyon, L.E.3    Skerry, T.M.4    Chenu, C.5
  • 85
    • 33747674263 scopus 로고    scopus 로고
    • The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment
    • Sawakami K., Robling A.G., Ai M., Pitner N.D., Liu D., Warden S.J., et al. The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment. J Biol Chem 2006 Aug 18, 281(33):23698-23711.
    • (2006) J Biol Chem , vol.281 , Issue.33 , pp. 23698-23711
    • Sawakami, K.1    Robling, A.G.2    Ai, M.3    Pitner, N.D.4    Liu, D.5    Warden, S.J.6
  • 86
    • 33846202013 scopus 로고    scopus 로고
    • Mechanical stimulation in vivo reduces osteocyte expression of sclerostin
    • Robling A.G., Bellido T., Turner C.H. Mechanical stimulation in vivo reduces osteocyte expression of sclerostin. J Musculoskelet Neuronal Interact 2006 Oct-Dec, 6(4):354.
    • (2006) J Musculoskelet Neuronal Interact , vol.6 , Issue.4 , pp. 354
    • Robling, A.G.1    Bellido, T.2    Turner, C.H.3
  • 87
    • 84882787335 scopus 로고    scopus 로고
    • Mechanical loading-related changes in osteocyte sclerostin expression in mice are more closely associated with the subsequent osteogenic response than the peak strains engendered
    • Moustafa A., Sugiyama T., Prasad J., Zaman G., Gross T.S., Lanyon L.E., et al. Mechanical loading-related changes in osteocyte sclerostin expression in mice are more closely associated with the subsequent osteogenic response than the peak strains engendered. Osteoporos Int 2011 May 15.
    • (2011) Osteoporos Int
    • Moustafa, A.1    Sugiyama, T.2    Prasad, J.3    Zaman, G.4    Gross, T.S.5    Lanyon, L.E.6
  • 88
    • 34249657953 scopus 로고    scopus 로고
    • Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction
    • Tatsumi S., Ishii K., Amizuka N., Li M., Kobayashi T., Kohno K., et al. Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction. Cell Metab 2007 Jun, 5(6):464-475.
    • (2007) Cell Metab , vol.5 , Issue.6 , pp. 464-475
    • Tatsumi, S.1    Ishii, K.2    Amizuka, N.3    Li, M.4    Kobayashi, T.5    Kohno, K.6
  • 89
    • 77952771209 scopus 로고    scopus 로고
    • Increased sclerostin serum levels associated with bone formation and resorption markers in patients with immobilization-induced bone loss
    • Gaudio A., Pennisi P., Bratengeier C., Torrisi V., Lindner B., Mangiafico R.A., et al. Increased sclerostin serum levels associated with bone formation and resorption markers in patients with immobilization-induced bone loss. J Clin Endocrinol Metab 2010 May, 95(5):2248-2253.
    • (2010) J Clin Endocrinol Metab , vol.95 , Issue.5 , pp. 2248-2253
    • Gaudio, A.1    Pennisi, P.2    Bratengeier, C.3    Torrisi, V.4    Lindner, B.5    Mangiafico, R.A.6
  • 90
    • 70349934212 scopus 로고    scopus 로고
    • Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling
    • Lin C., Jiang X., Dai Z., Guo X., Weng T., Wang J., et al. Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling. J Bone Miner Res 2009 Oct, 24(10):1651-1661.
    • (2009) J Bone Miner Res , vol.24 , Issue.10 , pp. 1651-1661
    • Lin, C.1    Jiang, X.2    Dai, Z.3    Guo, X.4    Weng, T.5    Wang, J.6
  • 91
    • 78650983826 scopus 로고    scopus 로고
    • Sclerostin antibody increases bone mass by stimulating bone formation and inhibiting bone resorption in a hindlimb-immobilization rat model
    • Tian X., Jee W.S., Li X., Paszty C., Ke H.Z. Sclerostin antibody increases bone mass by stimulating bone formation and inhibiting bone resorption in a hindlimb-immobilization rat model. Bone 2011 Feb, 48(2):197-201.
    • (2011) Bone , vol.48 , Issue.2 , pp. 197-201
    • Tian, X.1    Jee, W.S.2    Li, X.3    Paszty, C.4    Ke, H.Z.5
  • 92
    • 72949088669 scopus 로고    scopus 로고
    • Modulation of sclerostin expression by mechanical loading and bone morphogenetic proteins in osteogenic cells
    • Papanicolaou S.E., Phipps R.J., Fyhrie D.P., Genetos D.C. Modulation of sclerostin expression by mechanical loading and bone morphogenetic proteins in osteogenic cells. Biorheology 2009, 46(5):389-399.
    • (2009) Biorheology , vol.46 , Issue.5 , pp. 389-399
    • Papanicolaou, S.E.1    Phipps, R.J.2    Fyhrie, D.P.3    Genetos, D.C.4
  • 93
    • 33746134510 scopus 로고    scopus 로고
    • Global gene profiling reveals a downregulation of BMP gene expression in experimental atrophic nonunions compared to standard healing fractures
    • Niikura T., Hak D.J., Reddi A.H. Global gene profiling reveals a downregulation of BMP gene expression in experimental atrophic nonunions compared to standard healing fractures. J Orthop Res 2006 Jul, 24(7):1463-1471.
    • (2006) J Orthop Res , vol.24 , Issue.7 , pp. 1463-1471
    • Niikura, T.1    Hak, D.J.2    Reddi, A.H.3
  • 94
    • 33644865453 scopus 로고    scopus 로고
    • Recombinant human BMP-7 effectively prevents non-union in both young and old rats
    • Hak D.J., Makino T., Niikura T., Hazelwood S.J., Curtiss S., Reddi A.H. Recombinant human BMP-7 effectively prevents non-union in both young and old rats. J Orthop Res 2006 Jan, 24(1):11-20.
    • (2006) J Orthop Res , vol.24 , Issue.1 , pp. 11-20
    • Hak, D.J.1    Makino, T.2    Niikura, T.3    Hazelwood, S.J.4    Curtiss, S.5    Reddi, A.H.6
  • 95
    • 78650926548 scopus 로고    scopus 로고
    • Gene expression patterns in bone following mechanical loading
    • Mantila Roosa S.M., Liu Y., Turner C.H. Gene expression patterns in bone following mechanical loading. J Bone Miner Res 2011 Jan, 26(1):100-112.
    • (2011) J Bone Miner Res , vol.26 , Issue.1 , pp. 100-112
    • Mantila Roosa, S.M.1    Liu, Y.2    Turner, C.H.3
  • 96
    • 33846258531 scopus 로고
    • Ground substance, bone salts, and cellular activity in bone formation and destruction
    • Heller-Steinberg M. Ground substance, bone salts, and cellular activity in bone formation and destruction. Am J Anat 1951 Nov, 89(3):347-379.
    • (1951) Am J Anat , vol.89 , Issue.3 , pp. 347-379
    • Heller-Steinberg, M.1
  • 97
    • 79251524147 scopus 로고
    • Parathormone-induced osteolysis in dogs. a microradiographic and alpharadiographic survey
    • Belanger L.F., Robichon J. Parathormone-induced osteolysis in dogs. a microradiographic and alpharadiographic survey. J Bone Joint Surg Am 1964 Jul, 46:1008-1012.
    • (1964) J Bone Joint Surg Am , vol.46 , pp. 1008-1012
    • Belanger, L.F.1    Robichon, J.2
  • 98
    • 0014671748 scopus 로고
    • Osteocytic osteolysis
    • Belanger L.F. Osteocytic osteolysis. Calcif Tissue Res 1969 Aug 11, 4(1):1-12.
    • (1969) Calcif Tissue Res , vol.4 , Issue.1 , pp. 1-12
    • Belanger, L.F.1
  • 99
    • 57449116758 scopus 로고    scopus 로고
    • Do osteocytes contribute to bone mineral homeostasis? Osteocytic osteolysis revisited
    • Teti A., Zallone A. Do osteocytes contribute to bone mineral homeostasis? Osteocytic osteolysis revisited. Bone 2009 Jan, 44(1):11-16.
    • (2009) Bone , vol.44 , Issue.1 , pp. 11-16
    • Teti, A.1    Zallone, A.2
  • 100
    • 0343816924 scopus 로고
    • Evidence against osteocytic osteolysis
    • Societe Nouvelle de Publications Medicales et Dentaires, Paris, W.S.S. Jee, A.M. Parfitt (Eds.)
    • Boyde A. Evidence against osteocytic osteolysis. Bone Histomorphometry Third International Workshop 1980, Societe Nouvelle de Publications Medicales et Dentaires, Paris. W.S.S. Jee, A.M. Parfitt (Eds.).
    • (1980) Bone Histomorphometry Third International Workshop
    • Boyde, A.1
  • 101
    • 0018719467 scopus 로고
    • Time-related changes in the ultrastructure of osteoclasts after injection of parathyroid hormone in young rats
    • Holtrop M.E., King G.J., Cox K.A., Reit B. Time-related changes in the ultrastructure of osteoclasts after injection of parathyroid hormone in young rats. Calcif Tissue Int 1979 Apr 17, 27(2):129-135.
    • (1979) Calcif Tissue Int , vol.27 , Issue.2 , pp. 129-135
    • Holtrop, M.E.1    King, G.J.2    Cox, K.A.3    Reit, B.4
  • 102
    • 0017642753 scopus 로고
    • The cellular basis of bone turnover and bone loss: a rebuttal of the osteocytic resorption-bone flow theory
    • Parfitt A.M. The cellular basis of bone turnover and bone loss: a rebuttal of the osteocytic resorption-bone flow theory. Clin Orthop Relat Res 1977, (127):236-247.
    • (1977) Clin Orthop Relat Res , Issue.127 , pp. 236-247
    • Parfitt, A.M.1
  • 103
    • 79251469023 scopus 로고    scopus 로고
    • Osteocyte perilacunar remodeling is regulated hormonally, but not by mechanical unloading
    • Qing H., Ardeshirpor L., Dusevich V., Wysolmerski J., Bonewald L.F. Osteocyte perilacunar remodeling is regulated hormonally, but not by mechanical unloading. J Bone Min Res 2009, 29(Suppl 1):S440.
    • (2009) J Bone Min Res , vol.29 , Issue.SUPPL.1
    • Qing, H.1    Ardeshirpor, L.2    Dusevich, V.3    Wysolmerski, J.4    Bonewald, L.F.5
  • 104
    • 79958121208 scopus 로고    scopus 로고
    • The holy grail of high bone mass
    • Bonewald L. The holy grail of high bone mass. Nat Med 2011 Jun, 17(6):657-658.
    • (2011) Nat Med , vol.17 , Issue.6 , pp. 657-658
    • Bonewald, L.1
  • 105
    • 80053938104 scopus 로고    scopus 로고
    • Evidence for osteocyte regulation of bone homeostasis through RANKL expression
    • Nakashima T., Hayashi M., Fukunaga T., Kurata K., Oh-Hora M., Feng J.Q., et al. Evidence for osteocyte regulation of bone homeostasis through RANKL expression. Nat Med 2011, 17(10):1231-1234.
    • (2011) Nat Med , vol.17 , Issue.10 , pp. 1231-1234
    • Nakashima, T.1    Hayashi, M.2    Fukunaga, T.3    Kurata, K.4    Oh-Hora, M.5    Feng, J.Q.6
  • 107
    • 44449087410 scopus 로고    scopus 로고
    • Apoptotic bodies convey activity capable of initiating osteoclastogenesis and localized bone destruction
    • Kogianni G., Mann V., Noble B.S. Apoptotic bodies convey activity capable of initiating osteoclastogenesis and localized bone destruction. J Bone Miner Res 2008 Jun, 23(6):915-927.
    • (2008) J Bone Miner Res , vol.23 , Issue.6 , pp. 915-927
    • Kogianni, G.1    Mann, V.2    Noble, B.S.3
  • 108
    • 84882430955 scopus 로고
    • Die Normal Resorption des Knochengewebes und ihre Bedeutung die Entstehung der Typischen Knochenformen
    • Kolliker A. Die Normal Resorption des Knochengewebes und ihre Bedeutung die Entstehung der Typischen Knochenformen. Liepzig: Vogel FCW 1873.
    • (1873) Liepzig: Vogel FCW
    • Kolliker, A.1
  • 109
    • 0017467371 scopus 로고
    • The ultrastructure of the osteoclast and its functional implications
    • Holtrop M.E., King G.J. The ultrastructure of the osteoclast and its functional implications. Clin Orthop Relat Res 1977 Mar-Apr, (123):177-196.
    • (1977) Clin Orthop Relat Res , Issue.123 , pp. 177-196
    • Holtrop, M.E.1    King, G.J.2
  • 110
    • 0023784985 scopus 로고
    • Cellular biology and biochemical mechanism of bone resorption. A review of recent developments on the formation, activation, and mode of action of osteoclasts
    • Vaes G. Cellular biology and biochemical mechanism of bone resorption. A review of recent developments on the formation, activation, and mode of action of osteoclasts. Clin Orthop Relat Res 1988 Jun, (231):239-271.
    • (1988) Clin Orthop Relat Res , Issue.231 , pp. 239-271
    • Vaes, G.1
  • 111
    • 0029915491 scopus 로고    scopus 로고
    • Molecular mechanisms of bone resorption: therapeutic implications
    • Baron R. Molecular mechanisms of bone resorption: therapeutic implications. Rev Rhum Engl Ed 1996 Nov, 63(10):633-638.
    • (1996) Rev Rhum Engl Ed , vol.63 , Issue.10 , pp. 633-638
    • Baron, R.1
  • 112
    • 0025188739 scopus 로고
    • Protons and osteoclasts
    • Arnett T.R., Dempster D.W. Protons and osteoclasts. J Bone Miner Res 1990 Nov, 5(11):1099-1103.
    • (1990) J Bone Miner Res , vol.5 , Issue.11 , pp. 1099-1103
    • Arnett, T.R.1    Dempster, D.W.2
  • 113
    • 0021684621 scopus 로고
    • Osteoclast formation from mononuclear phagocytes: role of bone-forming cells
    • Burger E.H., van der Meer J.W., Nijweide P.J. Osteoclast formation from mononuclear phagocytes: role of bone-forming cells. J Cell Biol 1984 Dec, 99(6):1901-1906.
    • (1984) J Cell Biol , vol.99 , Issue.6 , pp. 1901-1906
    • Burger, E.H.1    van der Meer, J.W.2    Nijweide, P.J.3
  • 114
    • 0022445685 scopus 로고
    • In vitro osteoclast generation from different bone marrow fractions, including a highly enriched haematopoietic stem cell population
    • Scheven B.A., Visser J.W., Nijweide P.J. In vitro osteoclast generation from different bone marrow fractions, including a highly enriched haematopoietic stem cell population. Nature 1986 May 1-7, 321(6065):79-81.
    • (1986) Nature , vol.321 , Issue.6065 , pp. 79-81
    • Scheven, B.A.1    Visser, J.W.2    Nijweide, P.J.3
  • 115
    • 0022500788 scopus 로고
    • Abundant calcitonin receptors in isolated rat osteoclasts. Biochemical and autoradiographic characterization
    • Nicholson G.C., Moseley J.M., Sexton P.M., Mendelsohn F.A., Martin T.J. Abundant calcitonin receptors in isolated rat osteoclasts. Biochemical and autoradiographic characterization. J Clin Invest 1986 Aug, 78(2):355-360.
    • (1986) J Clin Invest , vol.78 , Issue.2 , pp. 355-360
    • Nicholson, G.C.1    Moseley, J.M.2    Sexton, P.M.3    Mendelsohn, F.A.4    Martin, T.J.5
  • 116
    • 0042047388 scopus 로고
    • Osteoclasts and the aging skeleton: a cytological, cytochemical and autoradiographic study
    • Tonna E.A. Osteoclasts and the aging skeleton: a cytological, cytochemical and autoradiographic study. Anat Rec 1960 Jul, 137:251-269.
    • (1960) Anat Rec , vol.137 , pp. 251-269
    • Tonna, E.A.1
  • 117
    • 0001471296 scopus 로고
    • Cell proliferation and specialization during endochondral osteogenesis in young rats
    • Young R.W. Cell proliferation and specialization during endochondral osteogenesis in young rats. J Cell Biol 1962 Sep, 14:357-370.
    • (1962) J Cell Biol , vol.14 , pp. 357-370
    • Young, R.W.1
  • 119
    • 0016794081 scopus 로고
    • Investigation of cell lineage in bone using a chimaera of chick and quial embryonic tissue
    • Kahn A.J., Simmons D.J. Investigation of cell lineage in bone using a chimaera of chick and quial embryonic tissue. Nature 1975 Nov 27, 258(5533):325-327.
    • (1975) Nature , vol.258 , Issue.5533 , pp. 325-327
    • Kahn, A.J.1    Simmons, D.J.2
  • 120
    • 0022969659 scopus 로고
    • Cells of bone: proliferation, differentiation, and hormonal regulation
    • Nijweide P.J., Burger E.H., Feyen J.H. Cells of bone: proliferation, differentiation, and hormonal regulation. Physiol Rev 1986 Oct, 66(4):855-886.
    • (1986) Physiol Rev , vol.66 , Issue.4 , pp. 855-886
    • Nijweide, P.J.1    Burger, E.H.2    Feyen, J.H.3
  • 121
    • 0019993809 scopus 로고
    • Longevity of osteoclasts in radiation chimaeras of osteopetrotic beige and normal mice
    • Loutit J.F., Townsend K.M. Longevity of osteoclasts in radiation chimaeras of osteopetrotic beige and normal mice. Br J Exp Pathol 1982 Apr, 63(2):221-223.
    • (1982) Br J Exp Pathol , vol.63 , Issue.2 , pp. 221-223
    • Loutit, J.F.1    Townsend, K.M.2
  • 122
    • 3643124625 scopus 로고
    • Prostaglandin effects on bone and role in cancer hypercalcaemia
    • Elsevier, Amsterdam, I. MacIntyre, M. Szelke (Eds.)
    • Martin T.J., Partridge N.C., Greaves M., Atkins D., Ibbotson K.J. Prostaglandin effects on bone and role in cancer hypercalcaemia. Molecular Endocrinology 1979, 251-264. Elsevier, Amsterdam. I. MacIntyre, M. Szelke (Eds.).
    • (1979) Molecular Endocrinology , pp. 251-264
    • Martin, T.J.1    Partridge, N.C.2    Greaves, M.3    Atkins, D.4    Ibbotson, K.J.5
  • 123
    • 0019847761 scopus 로고
    • Role of osteoblasts in hormonal control of bone resorption-a hypothesis
    • Rodan G.A., Martin T.J. Role of osteoblasts in hormonal control of bone resorption-a hypothesis. Calcif Tissue Int 1981, 33(4):349-351.
    • (1981) Calcif Tissue Int , vol.33 , Issue.4 , pp. 349-351
    • Rodan, G.A.1    Martin, T.J.2
  • 124
    • 0019057542 scopus 로고
    • Cof bone resorption
    • Chambers T.J. cof bone resorption. Clin Orthop Relat Res 1980 Sep, (151):283-293.
    • (1980) Clin Orthop Relat Res , Issue.151 , pp. 283-293
    • Chambers, T.J.1
  • 125
    • 0021962076 scopus 로고
    • The pathobiology of the osteoclast
    • Chambers T.J. The pathobiology of the osteoclast. J Clin Pathol 1985 Mar, 38(3):241-252.
    • (1985) J Clin Pathol , vol.38 , Issue.3 , pp. 241-252
    • Chambers, T.J.1
  • 126
    • 0024384368 scopus 로고
    • Parathyroid hormone (PTH)-related protein is a potent stimulator of osteoclast-like multinucleated cell formation to the same extent as PTH in mouse marrow cultures
    • Akatsu T., Takahashi N., Udagawa N., Sato K., Nagata N., Moseley J.M., et al. Parathyroid hormone (PTH)-related protein is a potent stimulator of osteoclast-like multinucleated cell formation to the same extent as PTH in mouse marrow cultures. Endocrinology 1989 Jul, 125(1):20-27.
    • (1989) Endocrinology , vol.125 , Issue.1 , pp. 20-27
    • Akatsu, T.1    Takahashi, N.2    Udagawa, N.3    Sato, K.4    Nagata, N.5    Moseley, J.M.6
  • 127
    • 0026061080 scopus 로고
    • Role of prostaglandins in interleukin-1-induced bone resorption in mice in vitro
    • Akatsu T., Takahashi N., Udagawa N., Imamura K., Yamaguchi A., Sato K., et al. Role of prostaglandins in interleukin-1-induced bone resorption in mice in vitro. J Bone Miner Res 1991 Feb, 6(2):183-189.
    • (1991) J Bone Miner Res , vol.6 , Issue.2 , pp. 183-189
    • Akatsu, T.1    Takahashi, N.2    Udagawa, N.3    Imamura, K.4    Yamaguchi, A.5    Sato, K.6
  • 128
    • 0027136189 scopus 로고
    • Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6
    • Tamura T., Udagawa N., Takahashi N., Miyaura C., Tanaka S., Yamada Y., et al. Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6. Proc Natl Acad Sci USA 1993 Dec 15, 90(24):11924-11928.
    • (1993) Proc Natl Acad Sci USA , vol.90 , Issue.24 , pp. 11924-11928
    • Tamura, T.1    Udagawa, N.2    Takahashi, N.3    Miyaura, C.4    Tanaka, S.5    Yamada, Y.6
  • 129
    • 0023928381 scopus 로고
    • Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures
    • Takahashi N., Yamana H., Yoshiki S., Roodman G.D., Mundy G.R., Jones S.J., et al. Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures. Endocrinology 1988 Apr, 122(4):1373-1382.
    • (1988) Endocrinology , vol.122 , Issue.4 , pp. 1373-1382
    • Takahashi, N.1    Yamana, H.2    Yoshiki, S.3    Roodman, G.D.4    Mundy, G.R.5    Jones, S.J.6
  • 130
    • 85003152202 scopus 로고
    • Modulation of osteoclast differentiation
    • Suda T., Takahashi N., Martin T.J. Modulation of osteoclast differentiation. Endocr Rev 1992 Feb, 13(1):66-80.
    • (1992) Endocr Rev , vol.13 , Issue.1 , pp. 66-80
    • Suda, T.1    Takahashi, N.2    Martin, T.J.3
  • 132
    • 0025601761 scopus 로고
    • Cloning of an osteoblastic cell line involved in the formation of osteoclast-like cells
    • Yamashita T., Asano K., Takahashi N., Akatsu T., Udagawa N., Sasaki T., et al. Cloning of an osteoblastic cell line involved in the formation of osteoclast-like cells. J Cell Physiol 1990 Dec, 145(3):587-595.
    • (1990) J Cell Physiol , vol.145 , Issue.3 , pp. 587-595
    • Yamashita, T.1    Asano, K.2    Takahashi, N.3    Akatsu, T.4    Udagawa, N.5    Sasaki, T.6
  • 133
    • 0024435957 scopus 로고
    • The bone marrow-derived stromal cell lines MC3T3-G2/PA6 and ST2 support osteoclast-like cell differentiation in cocultures with mouse spleen cells
    • Udagawa N., Takahashi N., Akatsu T., Sasaki T., Yamaguchi A., Kodama H., et al. The bone marrow-derived stromal cell lines MC3T3-G2/PA6 and ST2 support osteoclast-like cell differentiation in cocultures with mouse spleen cells. Endocrinology 1989 Oct, 125(4):1805-1813.
    • (1989) Endocrinology , vol.125 , Issue.4 , pp. 1805-1813
    • Udagawa, N.1    Takahashi, N.2    Akatsu, T.3    Sasaki, T.4    Yamaguchi, A.5    Kodama, H.6
  • 134
    • 0036289336 scopus 로고    scopus 로고
    • Vitamin D(3) augments osteoclastogenesis via vitamin D-responsive element of mouse RANKL gene promoter
    • Kitazawa R., Kitazawa S. Vitamin D(3) augments osteoclastogenesis via vitamin D-responsive element of mouse RANKL gene promoter. Biochem Biophys Res Commun 2002 Jan 18, 290(2):650-655.
    • (2002) Biochem Biophys Res Commun , vol.290 , Issue.2 , pp. 650-655
    • Kitazawa, R.1    Kitazawa, S.2
  • 135
    • 0028786577 scopus 로고
    • Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors
    • Udagawa N., Takahashi N., Katagiri T., Tamura T., Wada S., Findlay D.M., et al. Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors. J Exp Med 1995 Nov 1, 182(5):1461-1468.
    • (1995) J Exp Med , vol.182 , Issue.5 , pp. 1461-1468
    • Udagawa, N.1    Takahashi, N.2    Katagiri, T.3    Tamura, T.4    Wada, S.5    Findlay, D.M.6
  • 136
    • 0031980544 scopus 로고    scopus 로고
    • Expression of IL-6 receptor and GP130 in mouse bone marrow cells during osteoclast differentiation
    • Gao Y., Morita I., Maruo N., Kubota T., Murota S., Aso T. Expression of IL-6 receptor and GP130 in mouse bone marrow cells during osteoclast differentiation. Bone 1998 May, 22(5):487-493.
    • (1998) Bone , vol.22 , Issue.5 , pp. 487-493
    • Gao, Y.1    Morita, I.2    Maruo, N.3    Kubota, T.4    Murota, S.5    Aso, T.6
  • 137
    • 0028035150 scopus 로고
    • Mechanisms by which cells of the osteoblast lineage control osteoclast formation and activity
    • Martin T.J., Ng K.W. Mechanisms by which cells of the osteoblast lineage control osteoclast formation and activity. J Cell Biochem 1994 Nov, 56(3):357-366.
    • (1994) J Cell Biochem , vol.56 , Issue.3 , pp. 357-366
    • Martin, T.J.1    Ng, K.W.2
  • 138
    • 0031005576 scopus 로고    scopus 로고
    • Osteoprotegerin: a novel secreted protein involved in the regulation of bone density
    • Simonet W.S., Lacey D.L., Dunstan C.R., Kelley M., Chang M.S., Luthy R., et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 1997 Apr 18, 89(2):309-319.
    • (1997) Cell , vol.89 , Issue.2 , pp. 309-319
    • Simonet, W.S.1    Lacey, D.L.2    Dunstan, C.R.3    Kelley, M.4    Chang, M.S.5    Luthy, R.6
  • 139
    • 0030989969 scopus 로고    scopus 로고
    • Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis
    • Tsuda E., Goto M., Mochizuki S., Yano K., Kobayashi F., Morinaga T., et al. Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis. Biochem Biophys Res Commun 1997 May 8, 234(1):137-142.
    • (1997) Biochem Biophys Res Commun , vol.234 , Issue.1 , pp. 137-142
    • Tsuda, E.1    Goto, M.2    Mochizuki, S.3    Yano, K.4    Kobayashi, F.5    Morinaga, T.6
  • 140
    • 0032540319 scopus 로고    scopus 로고
    • Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
    • Lacey D.L., Timms E., Tan H.L., Kelley M.J., Dunstan C.R., Burgess T., et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 1998 Apr 17, 93(2):165-176.
    • (1998) Cell , vol.93 , Issue.2 , pp. 165-176
    • Lacey, D.L.1    Timms, E.2    Tan, H.L.3    Kelley, M.J.4    Dunstan, C.R.5    Burgess, T.6
  • 141
    • 0032584208 scopus 로고    scopus 로고
    • Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
    • Yasuda H., Shima N., Nakagawa N., Yamaguchi K., Kinosaki M., Mochizuki S., et al. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci USA 1998 Mar 31, 95(7):3597-3602.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.7 , pp. 3597-3602
    • Yasuda, H.1    Shima, N.2    Nakagawa, N.3    Yamaguchi, K.4    Kinosaki, M.5    Mochizuki, S.6
  • 142
    • 0032079445 scopus 로고    scopus 로고
    • Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification
    • Bucay N., Sarosi I., Dunstan C.R., Morony S., Tarpley J., Capparelli C., et al. osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification. Genes Dev 1998 May 1, 12(9):1260-1268.
    • (1998) Genes Dev , vol.12 , Issue.9 , pp. 1260-1268
    • Bucay, N.1    Sarosi, I.2    Dunstan, C.R.3    Morony, S.4    Tarpley, J.5    Capparelli, C.6
  • 143
    • 17744388339 scopus 로고    scopus 로고
    • Osteoprotegerin produced by osteoblasts is an important regulator in osteoclast development and function
    • Udagawa N., Takahashi N., Yasuda H., Mizuno A., Itoh K., Ueno Y., et al. Osteoprotegerin produced by osteoblasts is an important regulator in osteoclast development and function. Endocrinology 2000 Sep, 141(9):3478-3484.
    • (2000) Endocrinology , vol.141 , Issue.9 , pp. 3478-3484
    • Udagawa, N.1    Takahashi, N.2    Yasuda, H.3    Mizuno, A.4    Itoh, K.5    Ueno, Y.6
  • 144
    • 0033581952 scopus 로고    scopus 로고
    • Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
    • Kong Y.Y., Feige U., Sarosi I., Bolon B., Tafuri A., Morony S., et al. Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand. Nature 1999 Nov 18, 402(6759):304-309.
    • (1999) Nature , vol.402 , Issue.6759 , pp. 304-309
    • Kong, Y.Y.1    Feige, U.2    Sarosi, I.3    Bolon, B.4    Tafuri, A.5    Morony, S.6
  • 146
    • 0031439265 scopus 로고    scopus 로고
    • TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor
    • Wong B.R., Josien R., Lee S.Y., Sauter B., Li H.L., Steinman R.M., et al. TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor. J Exp Med 1997 Dec 15, 186(12):2075-2080.
    • (1997) J Exp Med , vol.186 , Issue.12 , pp. 2075-2080
    • Wong, B.R.1    Josien, R.2    Lee, S.Y.3    Sauter, B.4    Li, H.L.5    Steinman, R.M.6
  • 147
    • 0030714605 scopus 로고    scopus 로고
    • A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function
    • Anderson D.M., Maraskovsky E., Billingsley W.L., Dougall W.C., Tometsko M.E., Roux E.R., et al. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature 1997 Nov 13, 390(6656):175-179.
    • (1997) Nature , vol.390 , Issue.6656 , pp. 175-179
    • Anderson, D.M.1    Maraskovsky, E.2    Billingsley, W.L.3    Dougall, W.C.4    Tometsko, M.E.5    Roux, E.R.6
  • 149
    • 0033168518 scopus 로고    scopus 로고
    • Osteoclast differentiation factor acts as a multifunctional regulator in murine osteoclast differentiation and function
    • Jimi E., Akiyama S., Tsurukai T., Okahashi N., Kobayashi K., Udagawa N., et al. Osteoclast differentiation factor acts as a multifunctional regulator in murine osteoclast differentiation and function. J Immunol 1999 Jul 1, 163(1):434-442.
    • (1999) J Immunol , vol.163 , Issue.1 , pp. 434-442
    • Jimi, E.1    Akiyama, S.2    Tsurukai, T.3    Okahashi, N.4    Kobayashi, K.5    Udagawa, N.6
  • 150
    • 0031778505 scopus 로고    scopus 로고
    • Human osteoclast formation from blood monocytes, peritoneal macrophages, and bone marrow cells
    • Quinn J.M., Neale S., Fujikawa Y., McGee J.O., Athanasou N.A. Human osteoclast formation from blood monocytes, peritoneal macrophages, and bone marrow cells. Calcif Tissue Int 1998 Jun, 62(6):527-531.
    • (1998) Calcif Tissue Int , vol.62 , Issue.6 , pp. 527-531
    • Quinn, J.M.1    Neale, S.2    Fujikawa, Y.3    McGee, J.O.4    Athanasou, N.A.5
  • 151
    • 0032495975 scopus 로고    scopus 로고
    • Osteoclast differentiation factor (ODF) induces osteoclast-like cell formation in human peripheral blood mononuclear cell cultures
    • Matsuzaki K., Udagawa N., Takahashi N., Yamaguchi K., Yasuda H., Shima N., et al. Osteoclast differentiation factor (ODF) induces osteoclast-like cell formation in human peripheral blood mononuclear cell cultures. Biochem Biophys Res Commun 1998 May 8, 246(1):199-204.
    • (1998) Biochem Biophys Res Commun , vol.246 , Issue.1 , pp. 199-204
    • Matsuzaki, K.1    Udagawa, N.2    Takahashi, N.3    Yamaguchi, K.4    Yasuda, H.5    Shima, N.6
  • 152
    • 0031735152 scopus 로고    scopus 로고
    • Osteotropic agents regulate the expression of osteoclast differentiation factor and osteoprotegerin in osteoblastic stromal cells
    • Horwood N.J., Elliott J., Martin T.J., Gillespie M.T. Osteotropic agents regulate the expression of osteoclast differentiation factor and osteoprotegerin in osteoblastic stromal cells. Endocrinology 1998 Nov, 139(11):4743-4746.
    • (1998) Endocrinology , vol.139 , Issue.11 , pp. 4743-4746
    • Horwood, N.J.1    Elliott, J.2    Martin, T.J.3    Gillespie, M.T.4
  • 153
    • 0033305046 scopus 로고    scopus 로고
    • Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: correlation with osteoclast-like cell formation
    • Lee S.K., Lorenzo J.A. Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: correlation with osteoclast-like cell formation. Endocrinology 1999 Aug, 140(8):3552-3561.
    • (1999) Endocrinology , vol.140 , Issue.8 , pp. 3552-3561
    • Lee, S.K.1    Lorenzo, J.A.2
  • 154
    • 0033305222 scopus 로고    scopus 로고
    • Breast cancer cells interact with osteoblasts to support osteoclast formation
    • Thomas R.J., Guise T.A., Yin J.J., Elliott J., Horwood N.J., Martin T.J., et al. Breast cancer cells interact with osteoblasts to support osteoclast formation. Endocrinology 1999 Oct, 140(10):4451-4458.
    • (1999) Endocrinology , vol.140 , Issue.10 , pp. 4451-4458
    • Thomas, R.J.1    Guise, T.A.2    Yin, J.J.3    Elliott, J.4    Horwood, N.J.5    Martin, T.J.6
  • 155
    • 3242662500 scopus 로고    scopus 로고
    • Myeloma cells can directly contribute to the pool of RANKL in bone bypassing the classic stromal and osteoblast pathway of osteoclast stimulation
    • Lai F.P., Cole-Sinclair M., Cheng W.J., Quinn J.M., Gillespie M.T., Sentry J.W., et al. Myeloma cells can directly contribute to the pool of RANKL in bone bypassing the classic stromal and osteoblast pathway of osteoclast stimulation. Br J Haematol 2004 Jul, 126(2):192-201.
    • (2004) Br J Haematol , vol.126 , Issue.2 , pp. 192-201
    • Lai, F.P.1    Cole-Sinclair, M.2    Cheng, W.J.3    Quinn, J.M.4    Gillespie, M.T.5    Sentry, J.W.6
  • 156
    • 0037398261 scopus 로고    scopus 로고
    • Role of RANK ligand in mediating increased bone resorption in early postmenopausal women
    • Eghbali-Fatourechi G., Khosla S., Sanyal A., Boyle W.J., Lacey D.L., Riggs B.L. Role of RANK ligand in mediating increased bone resorption in early postmenopausal women. J Clin Invest 2003 Apr, 111(8):1221-1230.
    • (2003) J Clin Invest , vol.111 , Issue.8 , pp. 1221-1230
    • Eghbali-Fatourechi, G.1    Khosla, S.2    Sanyal, A.3    Boyle, W.J.4    Lacey, D.L.5    Riggs, B.L.6
  • 157
    • 0033304730 scopus 로고    scopus 로고
    • Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families
    • Suda T., Takahashi N., Udagawa N., Jimi E., Gillespie M.T., Martin T.J. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev 1999 Jun, 20(3):345-357.
    • (1999) Endocr Rev , vol.20 , Issue.3 , pp. 345-357
    • Suda, T.1    Takahashi, N.2    Udagawa, N.3    Jimi, E.4    Gillespie, M.T.5    Martin, T.J.6
  • 158
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • Boyle W.J., Simonet W.S., Lacey D.L. Osteoclast differentiation and activation. Nature 2003 May 15, 423(6937):337-342.
    • (2003) Nature , vol.423 , Issue.6937 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 159
    • 0043267732 scopus 로고    scopus 로고
    • Genetic regulation of osteoclast development and function
    • Teitelbaum S.L., Ross F.P. Genetic regulation of osteoclast development and function. Nat Rev Genet 2003 Aug, 4(8):638-649.
    • (2003) Nat Rev Genet , vol.4 , Issue.8 , pp. 638-649
    • Teitelbaum, S.L.1    Ross, F.P.2
  • 160
    • 38449087683 scopus 로고    scopus 로고
    • Ectodomain shedding of receptor activator of NF-kappaB ligand
    • Hikita A., Tanaka S. Ectodomain shedding of receptor activator of NF-kappaB ligand. Adv Exp Med Biol 2007, 602:15-21.
    • (2007) Adv Exp Med Biol , vol.602 , pp. 15-21
    • Hikita, A.1    Tanaka, S.2
  • 161
    • 0033532191 scopus 로고    scopus 로고
    • Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival
    • Lum L., Wong B.R., Josien R., Becherer J.D., Erdjument-Bromage H., Schlondorff J., et al. Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival. J Biol Chem 1999 May 7, 274(19):13613-13618.
    • (1999) J Biol Chem , vol.274 , Issue.19 , pp. 13613-13618
    • Lum, L.1    Wong, B.R.2    Josien, R.3    Becherer, J.D.4    Erdjument-Bromage, H.5    Schlondorff, J.6
  • 162
    • 21144438505 scopus 로고    scopus 로고
    • MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL
    • Lynch C.C., Hikosaka A., Acuff H.B., Martin M.D., Kawai N., Singh R.K., et al. MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL. Cancer Cell 2005 May, 7(5):485-496.
    • (2005) Cancer Cell , vol.7 , Issue.5 , pp. 485-496
    • Lynch, C.C.1    Hikosaka, A.2    Acuff, H.B.3    Martin, M.D.4    Kawai, N.5    Singh, R.K.6
  • 163
    • 33845994375 scopus 로고    scopus 로고
    • Negative regulation of osteoclastogenesis by ectodomain shedding of receptor activator of NF-kappaB ligand
    • Hikita A., Yana I., Wakeyama H., Nakamura M., Kadono Y., Oshima Y., et al. Negative regulation of osteoclastogenesis by ectodomain shedding of receptor activator of NF-kappaB ligand. J Biol Chem 2006 Dec 1, 281(48):36846-36855.
    • (2006) J Biol Chem , vol.281 , Issue.48 , pp. 36846-36855
    • Hikita, A.1    Yana, I.2    Wakeyama, H.3    Nakamura, M.4    Kadono, Y.5    Oshima, Y.6
  • 164
    • 0034076456 scopus 로고    scopus 로고
    • Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in rheumatoid synovium
    • Yamanaka H., Makino K., Takizawa M., Nakamura H., Fujimoto N., Moriya H., et al. Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in rheumatoid synovium. Lab Invest 2000 May, 80(5):677-687.
    • (2000) Lab Invest , vol.80 , Issue.5 , pp. 677-687
    • Yamanaka, H.1    Makino, K.2    Takizawa, M.3    Nakamura, H.4    Fujimoto, N.5    Moriya, H.6
  • 165
    • 77954355093 scopus 로고    scopus 로고
    • Shedding of RANKL by tumor-associated MT1-MMP activates Src-dependent prostate cancer cell migration
    • Sabbota A.L., Kim H.R., Zhe X., Fridman R., Bonfil R.D., Cher M.L. Shedding of RANKL by tumor-associated MT1-MMP activates Src-dependent prostate cancer cell migration. Cancer Res 2010 Jul 1, 70(13):5558-5566.
    • (2010) Cancer Res , vol.70 , Issue.13 , pp. 5558-5566
    • Sabbota, A.L.1    Kim, H.R.2    Zhe, X.3    Fridman, R.4    Bonfil, R.D.5    Cher, M.L.6
  • 166
    • 48649097728 scopus 로고    scopus 로고
    • Cathepsin G enhances mammary tumor-induced osteolysis by generating soluble receptor activator of nuclear factor-kappaB ligand
    • Wilson T.J., Nannuru K.C., Futakuchi M., Sadanandam A., Singh R.K. Cathepsin G enhances mammary tumor-induced osteolysis by generating soluble receptor activator of nuclear factor-kappaB ligand. Cancer Res 2008 Jul 15, 68(14):5803-5811.
    • (2008) Cancer Res , vol.68 , Issue.14 , pp. 5803-5811
    • Wilson, T.J.1    Nannuru, K.C.2    Futakuchi, M.3    Sadanandam, A.4    Singh, R.K.5
  • 167
    • 68849123934 scopus 로고    scopus 로고
    • Orchiectomy upregulates free soluble RANKL in bone marrow of aged rats
    • Proell V., Xu H., Schuler C., Weber K., Hofbauer L.C., Erben R.G. Orchiectomy upregulates free soluble RANKL in bone marrow of aged rats. Bone 2009 Oct, 45(4):677-681.
    • (2009) Bone , vol.45 , Issue.4 , pp. 677-681
    • Proell, V.1    Xu, H.2    Schuler, C.3    Weber, K.4    Hofbauer, L.C.5    Erben, R.G.6
  • 168
    • 0001505618 scopus 로고
    • Dynamics of bone remodeling
    • Frost
    • Frost Dynamics of bone remodeling. Bone Biodyn 1964, 1964:315-333.
    • (1964) Bone Biodyn , vol.1964 , pp. 315-333
  • 169
    • 0020023849 scopus 로고
    • The coupling of bone formation to bone resorption: a critical analysis of the concept and of its relevance to the pathogenesis of osteoporosis
    • Parfitt A.M. The coupling of bone formation to bone resorption: a critical analysis of the concept and of its relevance to the pathogenesis of osteoporosis. Metab Bone Dis Relat Res 1982, 4(1):1-6.
    • (1982) Metab Bone Dis Relat Res , vol.4 , Issue.1 , pp. 1-6
    • Parfitt, A.M.1
  • 170
    • 0022815786 scopus 로고
    • Normal and pathological remodeling of human trabecular bone: three dimensional reconstruction of the remodeling sequence in normals and in metabolic bone disease
    • Eriksen E.F. Normal and pathological remodeling of human trabecular
    • (1986) Endocr Rev , vol.7 , Issue.4 , pp. 379-408
    • Eriksen, E.F.1
  • 171
    • 58849164046 scopus 로고    scopus 로고
    • Molecular mechanisms in coupling of bone formation to resorption
    • Martin T.J., Gooi J.H., Sims N.A. Molecular mechanisms in coupling of bone formation to resorption. Crit Rev Eukaryot Gene Expr 2009, 19:73-88.
    • (2009) Crit Rev Eukaryot Gene Expr , vol.19 , pp. 73-88
    • Martin, T.J.1    Gooi, J.H.2    Sims, N.A.3
  • 172
    • 0018222773 scopus 로고
    • Mean wall thickness of trabecular bone packets in the human iliac crest: changes with age
    • Lips P., Courpron P., Meunier P.J. Mean wall thickness of trabecular bone packets in the human iliac crest: changes with age. Calcif Tissue Res 1978 Nov 10, 26(1):13-17.
    • (1978) Calcif Tissue Res , vol.26 , Issue.1 , pp. 13-17
    • Lips, P.1    Courpron, P.2    Meunier, P.J.3
  • 173
    • 0034874481 scopus 로고    scopus 로고
    • Cancellous bone remodeling occurs in specialized compartments lined by cells expressing osteoblastic markers
    • Hauge E.M., Qvesel D., Eriksen E.F., Mosekilde L., Melsen F. Cancellous bone remodeling occurs in specialized compartments lined by cells expressing osteoblastic markers. J Bone Miner Res 2001 Sep, 16(9):1575-1582.
    • (2001) J Bone Miner Res , vol.16 , Issue.9 , pp. 1575-1582
    • Hauge, E.M.1    Qvesel, D.2    Eriksen, E.F.3    Mosekilde, L.4    Melsen, F.5
  • 174
    • 0029793393 scopus 로고    scopus 로고
    • The human osteoclast precursor circulates in the monocyte fraction
    • Fujikawa Y., Quinn J.M., Sabokbar A., McGee J.O., Athanasou N.A. The human osteoclast precursor circulates in the monocyte fraction. Endocrinology 1996 Sep, 137(9):4058-4060.
    • (1996) Endocrinology , vol.137 , Issue.9 , pp. 4058-4060
    • Fujikawa, Y.1    Quinn, J.M.2    Sabokbar, A.3    McGee, J.O.4    Athanasou, N.A.5
  • 177
    • 27744466811 scopus 로고    scopus 로고
    • The postnatal rat aorta contains pericyte progenitor cells that form spheroidal colonies in suspension culture
    • Howson K.M., Aplin A.C., Gelati M., Alessandri G., Parati E.A., Nicosia R.F. The postnatal rat aorta contains pericyte progenitor cells that form spheroidal colonies in suspension culture. Am J Physiol Cell Physiol 2005 Dec, 289(6):C1396-C1407.
    • (2005) Am J Physiol Cell Physiol , vol.289 , Issue.6
    • Howson, K.M.1    Aplin, A.C.2    Gelati, M.3    Alessandri, G.4    Parati, E.A.5    Nicosia, R.F.6
  • 178
    • 34047266512 scopus 로고    scopus 로고
    • Therapeutic potential of vasculogenesis and osteogenesis promoted by peripheral blood CD34-positive cells for functional bone healing
    • Matsumoto T., Kawamoto A., Kuroda R., Ishikawa M., Mifune Y., Iwasaki H., et al. Therapeutic potential of vasculogenesis and osteogenesis promoted by peripheral blood CD34-positive cells for functional bone healing. Am J Pathol 2006 Oct, 169(4):1440-1457.
    • (2006) Am J Pathol , vol.169 , Issue.4 , pp. 1440-1457
    • Matsumoto, T.1    Kawamoto, A.2    Kuroda, R.3    Ishikawa, M.4    Mifune, Y.5    Iwasaki, H.6
  • 179
    • 33745173528 scopus 로고    scopus 로고
    • Osteoblasts provide a suitable microenvironment for the action of receptor activator of nuclear factor-kappaB ligand
    • Yamamoto Y., Udagawa N., Matsuura S., Nakamichi Y., Horiuchi H., Hosoya A., et al. Osteoblasts provide a suitable microenvironment for the action of receptor activator of nuclear factor-kappaB ligand. Endocrinology 2006 Jul, 147(7):3366-3374.
    • (2006) Endocrinology , vol.147 , Issue.7 , pp. 3366-3374
    • Yamamoto, Y.1    Udagawa, N.2    Matsuura, S.3    Nakamichi, Y.4    Horiuchi, H.5    Hosoya, A.6
  • 180
    • 61449147145 scopus 로고    scopus 로고
    • Identification of cell cycle-arrested quiescent osteoclast precursors in vivo
    • Mizoguchi T., Muto A., Udagawa N., Arai A., Yamashita T., Hosoya A., et al. Identification of cell cycle-arrested quiescent osteoclast precursors in vivo. J Cell Biol 2009 Feb 23, 184(4):541-554.
    • (2009) J Cell Biol , vol.184 , Issue.4 , pp. 541-554
    • Mizoguchi, T.1    Muto, A.2    Udagawa, N.3    Arai, A.4    Yamashita, T.5    Hosoya, A.6
  • 181
    • 0020409812 scopus 로고
    • Dissociation of organic acid secretion from macrophage mediated bone resorption
    • Malone J.D., Kahn A.J., Teitelbaum S.L. Dissociation of organic acid secretion from macrophage mediated bone resorption. Biochem Biophys Res Commun 1982 Sep 30, 108(2):468-473.
    • (1982) Biochem Biophys Res Commun , vol.108 , Issue.2 , pp. 468-473
    • Malone, J.D.1    Kahn, A.J.2    Teitelbaum, S.L.3
  • 182
    • 0347397553 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 (SDF-1) recruits osteoclast precursors by inducing chemotaxis, matrix metalloproteinase-9 (MMP-9) activity, and collagen transmigration
    • Yu X., Huang Y., Collin-Osdoby P., Osdoby P. Stromal cell-derived factor-1 (SDF-1) recruits osteoclast precursors by inducing chemotaxis, matrix metalloproteinase-9 (MMP-9) activity, and collagen transmigration. J Bone Miner Res 2003 Aug, 18(8):1404-1418.
    • (2003) J Bone Miner Res , vol.18 , Issue.8 , pp. 1404-1418
    • Yu, X.1    Huang, Y.2    Collin-Osdoby, P.3    Osdoby, P.4
  • 183
    • 0033981552 scopus 로고    scopus 로고
    • Loss of osteocyte integrity in association with microdamage and bone remodeling after fatigue in vivo
    • Verborgt O., Gibson G.J., Schaffler M.B. Loss of osteocyte integrity in association with microdamage and bone remodeling after fatigue in vivo. J Bone Miner Res 2000 Jan, 15(1):60-67.
    • (2000) J Bone Miner Res , vol.15 , Issue.1 , pp. 60-67
    • Verborgt, O.1    Gibson, G.J.2    Schaffler, M.B.3
  • 184
    • 0036236905 scopus 로고    scopus 로고
    • Spatial distribution of Bax and Bcl-2 in osteocytes after bone fatigue: complementary roles in bone remodeling regulation?
    • Verborgt O., Tatton N.A., Majeska R.J., Schaffler M.B. Spatial distribution of Bax and Bcl-2 in osteocytes after bone fatigue: complementary roles in bone remodeling regulation?. J Bone Miner Res 2002 May, 17(5):907-914.
    • (2002) J Bone Miner Res , vol.17 , Issue.5 , pp. 907-914
    • Verborgt, O.1    Tatton, N.A.2    Majeska, R.J.3    Schaffler, M.B.4
  • 185
    • 0037376698 scopus 로고    scopus 로고
    • Mechanical loading: biphasic osteocyte survival and targeting of osteoclasts for bone destruction in rat cortical bone
    • Noble B.S., Peet N., Stevens H.Y., Brabbs A., Mosley J.R., Reilly G.C., et al. Mechanical loading: biphasic osteocyte survival and targeting of osteoclasts for bone destruction in rat cortical bone. Am J Physiol Cell Physiol 2003 Apr, 284(4):C934-C943.
    • (2003) Am J Physiol Cell Physiol , vol.284 , Issue.4
    • Noble, B.S.1    Peet, N.2    Stevens, H.Y.3    Brabbs, A.4    Mosley, J.R.5    Reilly, G.C.6
  • 186
    • 0037129205 scopus 로고    scopus 로고
    • RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-beta
    • Takayanagi H., Kim S., Matsuo K., Suzuki H., Suzuki T., Sato K., et al. RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-beta. Nature 2002 Apr 18, 416(6882):744-749.
    • (2002) Nature , vol.416 , Issue.6882 , pp. 744-749
    • Takayanagi, H.1    Kim, S.2    Matsuo, K.3    Suzuki, H.4    Suzuki, T.5    Sato, K.6
  • 187
    • 0028173214 scopus 로고
    • C-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling
    • Grigoriadis A.E., Wang Z.Q., Cecchini M.G., Hofstetter W., Felix R., Fleisch H.A., et al. c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling. Science 1994 Oct 21, 266(5184):443-448.
    • (1994) Science , vol.266 , Issue.5184 , pp. 443-448
    • Grigoriadis, A.E.1    Wang, Z.Q.2    Cecchini, M.G.3    Hofstetter, W.4    Felix, R.5    Fleisch, H.A.6
  • 188
    • 33746528704 scopus 로고    scopus 로고
    • Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis
    • Zhao C., Irie N., Takada Y., Shimoda K., Miyamoto T., Nishiwaki T., et al. Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis. Cell Metab 2006 Aug, 4(2):111-121.
    • (2006) Cell Metab , vol.4 , Issue.2 , pp. 111-121
    • Zhao, C.1    Irie, N.2    Takada, Y.3    Shimoda, K.4    Miyamoto, T.5    Nishiwaki, T.6
  • 189
    • 0030722948 scopus 로고    scopus 로고
    • Apoptosis in bone physiology and disease
    • Hughes D.E., Boyce B.F. Apoptosis in bone physiology and disease. Mol Pathol 1997 Jun, 50(3):132-137.
    • (1997) Mol Pathol , vol.50 , Issue.3 , pp. 132-137
    • Hughes, D.E.1    Boyce, B.F.2
  • 190
    • 34548274444 scopus 로고    scopus 로고
    • Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts
    • Nakamura T., Imai Y., Matsumoto T., Sato S., Takeuchi K., Igarashi K., et al. Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts. Cell 2007 Sep 7, 130(5):811-823.
    • (2007) Cell , vol.130 , Issue.5 , pp. 811-823
    • Nakamura, T.1    Imai, Y.2    Matsumoto, T.3    Sato, S.4    Takeuchi, K.5    Igarashi, K.6
  • 191
    • 1942533447 scopus 로고    scopus 로고
    • Characterization of osteoclasts from patients harboring a G215R mutation in ClC-7 causing autosomal dominant osteopetrosis type II
    • Henriksen K., Gram J., Schaller S., Dahl B.H., Dziegiel M.H., Bollerslev J., et al. Characterization of osteoclasts from patients harboring a G215R mutation in ClC-7 causing autosomal dominant osteopetrosis type II. Am J Pathol 2004 May, 164(5):1537-1545.
    • (2004) Am J Pathol , vol.164 , Issue.5 , pp. 1537-1545
    • Henriksen, K.1    Gram, J.2    Schaller, S.3    Dahl, B.H.4    Dziegiel, M.H.5    Bollerslev, J.6
  • 192
    • 19944432718 scopus 로고    scopus 로고
    • Acidification of the osteoclastic resorption compartment provides insight into the coupling of bone formation to bone resorption
    • Karsdal M.A., Henriksen K., Sorensen M.G., Gram J., Schaller S., Dziegiel M.H., et al. Acidification of the osteoclastic resorption compartment provides insight into the coupling of bone formation to bone resorption. Am J Pathol 2005 Feb, 166(2):467-476.
    • (2005) Am J Pathol , vol.166 , Issue.2 , pp. 467-476
    • Karsdal, M.A.1    Henriksen, K.2    Sorensen, M.G.3    Gram, J.4    Schaller, S.5    Dziegiel, M.H.6
  • 194
    • 20444400468 scopus 로고    scopus 로고
    • (Pre-)osteoclasts induce retraction of osteoblasts before their fusion to osteoclasts
    • Perez-Amodio S., Beertsen W., Everts V. (Pre-)osteoclasts induce retraction of osteoblasts before their fusion to osteoclasts. J Bone Miner Res 2004 Oct, 19(10):1722-1731.
    • (2004) J Bone Miner Res , vol.19 , Issue.10 , pp. 1722-1731
    • Perez-Amodio, S.1    Beertsen, W.2    Everts, V.3
  • 195
    • 12344291865 scopus 로고    scopus 로고
    • Bone morphogenetic proteins
    • Chen D., Zhao M., Mundy G.R. Bone morphogenetic proteins. Growth Factors 2004 Dec, 22(4):233-241.
    • (2004) Growth Factors , vol.22 , Issue.4 , pp. 233-241
    • Chen, D.1    Zhao, M.2    Mundy, G.R.3
  • 196
    • 0026770377 scopus 로고
    • Integrins: versatility, modulation, and signaling in cell adhesion
    • Hynes R.O. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 1992 Apr 3, 69(1):11-25.
    • (1992) Cell , vol.69 , Issue.1 , pp. 11-25
    • Hynes, R.O.1
  • 198
    • 0023037767 scopus 로고
    • Growth factors in bone matrix. Isolation of multiple types by affinity chromatography on heparin-Sepharose
    • Hauschka P.V., Mavrakos A.E., Iafrati M.D., Doleman S.E., Klagsbrun M. Growth factors in bone matrix. Isolation of multiple types by affinity chromatography on heparin-Sepharose. J Biol Chem 1986 Sep 25, 261(27):12665-12674.
    • (1986) J Biol Chem , vol.261 , Issue.27 , pp. 12665-12674
    • Hauschka, P.V.1    Mavrakos, A.E.2    Iafrati, M.D.3    Doleman, S.E.4    Klagsbrun, M.5
  • 199
    • 0028345076 scopus 로고
    • The effects of age on the response of rabbit periosteal osteoprogenitor cells to exogenous transforming growth factor-beta 2
    • Critchlow M.A., Bland Y.S., Ashhurst D.E. The effects of age on the response of rabbit periosteal osteoprogenitor cells to exogenous transforming growth factor-beta 2. J Cell Sci 1994 Feb, 107(Pt 2):499-516.
    • (1994) J Cell Sci , vol.107 , Issue.PT 2 , pp. 499-516
    • Critchlow, M.A.1    Bland, Y.S.2    Ashhurst, D.E.3
  • 200
    • 0025340885 scopus 로고
    • Transforming growth factor-beta and the initiation of chondrogenesis and osteogenesis in the rat femur
    • Joyce M.E., Roberts A.B., Sporn M.B., Bolander M.E. Transforming growth factor-beta and the initiation of chondrogenesis and osteogenesis in the rat femur. J Cell Biol 1990 Jun, 110(6):2195-2207.
    • (1990) J Cell Biol , vol.110 , Issue.6 , pp. 2195-2207
    • Joyce, M.E.1    Roberts, A.B.2    Sporn, M.B.3    Bolander, M.E.4
  • 201
    • 0025998393 scopus 로고
    • Latent forms of transforming growth factor-beta (TGF beta) derived from bone cultures: identification of a naturally occurring 100-kDa complex with similarity to recombinant latent TGF beta
    • Bonewald L.F., Wakefield L., Oreffo R.O., Escobedo A., Twardzik D.R., Mundy G.R. Latent forms of transforming growth factor-beta (TGF beta) derived from bone cultures: identification of a naturally occurring 100-kDa complex with similarity to recombinant latent TGF beta. Mol Endocrinol 1991 Jun, 5(6):741-751.
    • (1991) Mol Endocrinol , vol.5 , Issue.6 , pp. 741-751
    • Bonewald, L.F.1    Wakefield, L.2    Oreffo, R.O.3    Escobedo, A.4    Twardzik, D.R.5    Mundy, G.R.6
  • 202
    • 0027749317 scopus 로고
    • The plasminogen activator and inhibitor system in bone remodelling
    • Martin T.J., Allan E.H., Fukumoto S. The plasminogen activator and inhibitor system in bone remodelling. Growth Regul 1993 Dec, 3(4):209-214.
    • (1993) Growth Regul , vol.3 , Issue.4 , pp. 209-214
    • Martin, T.J.1    Allan, E.H.2    Fukumoto, S.3
  • 203
    • 67650506105 scopus 로고    scopus 로고
    • TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation
    • Tang Y., Wu X., Lei W., Pang L., Wan C., Shi Z., et al. TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation. Nat Med 2009 Jul, 15(7):757-765.
    • (2009) Nat Med , vol.15 , Issue.7 , pp. 757-765
    • Tang, Y.1    Wu, X.2    Lei, W.3    Pang, L.4    Wan, C.5    Shi, Z.6
  • 204
    • 78049510298 scopus 로고    scopus 로고
    • Inhibition of Sca-1-positive skeletal stem cell recruitment by alendronate blunts the anabolic effects of parathyroid hormone on bone remodeling
    • Wu X., Pang L., Lei W., Lu W., Li J., Li Z., et al. Inhibition of Sca-1-positive skeletal stem cell recruitment by alendronate blunts the anabolic effects of parathyroid hormone on bone remodeling. Cell Stem Cell 2010 Nov 5, 7(5):571-580.
    • (2010) Cell Stem Cell , vol.7 , Issue.5 , pp. 571-580
    • Wu, X.1    Pang, L.2    Lei, W.3    Lu, W.4    Li, J.5    Li, Z.6
  • 205
    • 0030002099 scopus 로고    scopus 로고
    • Topographically induced bone formation in vitro: implications for bone implants and bone grafts
    • Gray C., Boyde A., Jones S.J. Topographically induced bone formation in vitro: implications for bone implants and bone grafts. Bone 1996 Feb, 18(2):115-123.
    • (1996) Bone , vol.18 , Issue.2 , pp. 115-123
    • Gray, C.1    Boyde, A.2    Jones, S.J.3
  • 206
    • 28944448540 scopus 로고    scopus 로고
    • Gap junctions in skeletal development and function
    • Stains J.P., Civitelli R. Gap junctions in skeletal development and function. Biochim Biophys Acta 2005 Dec 20, 1719(1-2):69-81.
    • (2005) Biochim Biophys Acta , vol.1719 , Issue.1-2 , pp. 69-81
    • Stains, J.P.1    Civitelli, R.2
  • 208
    • 47849098824 scopus 로고    scopus 로고
    • EphrinB2 regulation by PTH and PTHrP revealed by molecular profiling in differentiating osteoblasts
    • Allan E.H., Hausler K.D., Wei T., Gooi J.H., Quinn J.M., Crimeen-Irwin B., et al. EphrinB2 regulation by PTH and PTHrP revealed by molecular profiling in differentiating osteoblasts. J Bone Miner Res 2008 Aug, 23(8):1170-1181.
    • (2008) J Bone Miner Res , vol.23 , Issue.8 , pp. 1170-1181
    • Allan, E.H.1    Hausler, K.D.2    Wei, T.3    Gooi, J.H.4    Quinn, J.M.5    Crimeen-Irwin, B.6
  • 209
    • 15844429889 scopus 로고    scopus 로고
    • Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis
    • Gale N.W., Holland S.J., Valenzuela D.M., Flenniken A., Pan L., Ryan T.E., et al. Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis. Neuron 1996 Jul, 17(1):9-19.
    • (1996) Neuron , vol.17 , Issue.1 , pp. 9-19
    • Gale, N.W.1    Holland, S.J.2    Valenzuela, D.M.3    Flenniken, A.4    Pan, L.5    Ryan, T.E.6
  • 210
    • 20344396123 scopus 로고    scopus 로고
    • Eph receptor signalling casts a wide net on cell behaviour
    • Pasquale E.B. Eph receptor signalling casts a wide net on cell behaviour. Nat Rev Mol Cell Biol 2005 Jun, 6(6):462-475.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , Issue.6 , pp. 462-475
    • Pasquale, E.B.1
  • 211
    • 72749094300 scopus 로고    scopus 로고
    • Intermittent PTH administration stimulates pre-osteoblastic proliferation without leading to enhanced bone formation in osteoclast-less c-fos(-/-) mice
    • Luiz de Freitas P.H., Li M., Ninomiya T., Nakamura M., Ubaidus S., Oda K., et al. Intermittent PTH administration stimulates pre-osteoblastic proliferation without leading to enhanced bone formation in osteoclast-less c-fos(-/-) mice. J Bone Miner Res 2009 Sep, 24(9):1586-1597.
    • (2009) J Bone Miner Res , vol.24 , Issue.9 , pp. 1586-1597
    • Luiz de Freitas, P.H.1    Li, M.2    Ninomiya, T.3    Nakamura, M.4    Ubaidus, S.5    Oda, K.6
  • 212
    • 33645789497 scopus 로고    scopus 로고
    • Clinical, genetic, and cellular analysis of 49 osteopetrotic patients: implications for diagnosis and treatment
    • Del Fattore A., Peruzzi B., Rucci N., Recchia I., Cappariello A., Longo M., et al. Clinical, genetic, and cellular analysis of 49 osteopetrotic patients: implications for diagnosis and treatment. J Med Genet 2006 Apr, 43(4):315-325.
    • (2006) J Med Genet , vol.43 , Issue.4 , pp. 315-325
    • Del Fattore, A.1    Peruzzi, B.2    Rucci, N.3    Recchia, I.4    Cappariello, A.5    Longo, M.6
  • 213
    • 0026023289 scopus 로고
    • Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
    • Soriano P., Montgomery C., Geske R., Bradley A. Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 1991 Feb 22, 64(4):693-702.
    • (1991) Cell , vol.64 , Issue.4 , pp. 693-702
    • Soriano, P.1    Montgomery, C.2    Geske, R.3    Bradley, A.4
  • 214
    • 0035951282 scopus 로고    scopus 로고
    • Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man
    • Kornak U., Kasper D., Bosl M.R., Kaiser E., Schweizer M., Schulz A., et al. Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man. Cell 2001 Jan 26, 104(2):205-215.
    • (2001) Cell , vol.104 , Issue.2 , pp. 205-215
    • Kornak, U.1    Kasper, D.2    Bosl, M.R.3    Kaiser, E.4    Schweizer, M.5    Schulz, A.6
  • 215
    • 58249097157 scopus 로고    scopus 로고
    • Bone density, strength, and formation in adult cathepsin K (-/-) mice
    • Pennypacker B., Shea M., Liu Q., Masarachia P., Saftig P., Rodan S., et al. Bone density, strength, and formation in adult cathepsin K (-/-) mice. Bone 2009 Feb, 44(2):199-207.
    • (2009) Bone , vol.44 , Issue.2 , pp. 199-207
    • Pennypacker, B.1    Shea, M.2    Liu, Q.3    Masarachia, P.4    Saftig, P.5    Rodan, S.6
  • 216
    • 9144223721 scopus 로고    scopus 로고
    • Tyrosine phosphatase epsilon is a positive regulator of osteoclast function in vitro and in vivo
    • Chiusaroli R., Knobler H., Luxenburg C., Sanjay A., Granot-Attas S., Tiran Z., et al. Tyrosine phosphatase epsilon is a positive regulator of osteoclast function in vitro and in vivo. Mol Biol Cell 2004 Jan, 15(1):234-244.
    • (2004) Mol Biol Cell , vol.15 , Issue.1 , pp. 234-244
    • Chiusaroli, R.1    Knobler, H.2    Luxenburg, C.3    Sanjay, A.4    Granot-Attas, S.5    Tiran, Z.6
  • 217
    • 33845537394 scopus 로고    scopus 로고
    • V-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation
    • Lee S.H., Rho J., Jeong D., Sul J.Y., Kim T., Kim N., et al. v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation. Nat Med 2006 Dec, 12(12):1403-1409.
    • (2006) Nat Med , vol.12 , Issue.12 , pp. 1403-1409
    • Lee, S.H.1    Rho, J.2    Jeong, D.3    Sul, J.Y.4    Kim, T.5    Kim, N.6
  • 218
    • 85047691524 scopus 로고    scopus 로고
    • Glycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways
    • Sims N.A., Jenkins B.J., Quinn J.M., Nakamura A., Glatt M., Gillespie M.T., et al. Glycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways. J Clin Invest 2004 Feb, 113(3):379-389.
    • (2004) J Clin Invest , vol.113 , Issue.3 , pp. 379-389
    • Sims, N.A.1    Jenkins, B.J.2    Quinn, J.M.3    Nakamura, A.4    Glatt, M.5    Gillespie, M.T.6
  • 219
    • 13244267455 scopus 로고    scopus 로고
    • Osteoclast-derived activity in the coupling of bone formation to resorption
    • Martin T.J., Sims N.A. Osteoclast-derived activity in the coupling of bone formation to resorption. Trends Mol Med 2005 Feb, 11(2):76-81.
    • (2005) Trends Mol Med , vol.11 , Issue.2 , pp. 76-81
    • Martin, T.J.1    Sims, N.A.2
  • 220
    • 0037073709 scopus 로고    scopus 로고
    • Interleukin-11 as a stimulatory factor for bone formation prevents bone loss with advancing age in mice
    • Takeuchi Y., Watanabe S., Ishii G., Takeda S., Nakayama K., Fukumoto S., et al. Interleukin-11 as a stimulatory factor for bone formation prevents bone loss with advancing age in mice. J Biol Chem 2002 Dec 13, 277(50):49011-49018.
    • (2002) J Biol Chem , vol.277 , Issue.50 , pp. 49011-49018
    • Takeuchi, Y.1    Watanabe, S.2    Ishii, G.3    Takeda, S.4    Nakayama, K.5    Fukumoto, S.6
  • 221
    • 0027407272 scopus 로고
    • The effect of leukemia inhibitory factor on bone in vivo
    • Cornish J., Callon K., King A., Edgar S., Reid I.R. The effect of leukemia inhibitory factor on bone in vivo. Endocrinology 1993 Mar, 132(3):1359-1366.
    • (1993) Endocrinology , vol.132 , Issue.3 , pp. 1359-1366
    • Cornish, J.1    Callon, K.2    King, A.3    Edgar, S.4    Reid, I.R.5
  • 222
    • 58549115903 scopus 로고    scopus 로고
    • Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate
    • Pederson L., Ruan M., Westendorf J.J., Khosla S., Oursler M.J. Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate. Proc Natl Acad Sci USA 2008 Dec 30, 105(52):20764-20769.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.52 , pp. 20764-20769
    • Pederson, L.1    Ruan, M.2    Westendorf, J.J.3    Khosla, S.4    Oursler, M.J.5
  • 223
    • 14344279878 scopus 로고    scopus 로고
    • Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia
    • Shimada T., Mizutani S., Muto T., Yoneya T., Hino R., Takeda S., et al. Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia. Proc Natl Acad Sci USA 2001 May 22, 98(11):6500-6505.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.11 , pp. 6500-6505
    • Shimada, T.1    Mizutani, S.2    Muto, T.3    Yoneya, T.4    Hino, R.5    Takeda, S.6
  • 224
    • 77955035304 scopus 로고    scopus 로고
    • Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism
    • Ferron M., Wei J., Yoshizawa T., Del Fattore A., DePinho R.A., Teti A., et al. Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism. Cell 2010 Jul 23, 142(2):296-308.
    • (2010) Cell , vol.142 , Issue.2 , pp. 296-308
    • Ferron, M.1    Wei, J.2    Yoshizawa, T.3    Del Fattore, A.4    DePinho, R.A.5    Teti, A.6
  • 225
    • 79952289069 scopus 로고    scopus 로고
    • Endocrine regulation of male fertility by the skeleton
    • Oury F., Sumara G., Sumara O., Ferron M., Chang H., Smith C.E., et al. Endocrine regulation of male fertility by the skeleton. Cell 2011 Mar 4, 144(5):796-809.
    • (2011) Cell , vol.144 , Issue.5 , pp. 796-809
    • Oury, F.1    Sumara, G.2    Sumara, O.3    Ferron, M.4    Chang, H.5    Smith, C.E.6


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