메뉴 건너뛰기




Volumn 26, Issue 1, 2008, Pages 223-234

Circulating bone marrow-derived osteoblast progenitor cells are recruited to the bone-forming site by the CXCR4/stromal cell-derived factor-1 pathway

Author keywords

Bone marrow cells; Chemokine receptor CXCR4; Mobilization kinetics; Osteoblast; Peripheral blood; Stem progenitor cell; Stromal derived factor 1; Tissue regeneration

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; CD45 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; HERMES ANTIGEN; OSTEOPONTIN; OSTEOPONTIN RECEPTOR; STROMAL CELL DERIVED FACTOR 1; UNCLASSIFIED DRUG;

EID: 38349073636     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2007-0515     Document Type: Article
Times cited : (259)

References (51)
  • 1
    • 0037019337 scopus 로고    scopus 로고
    • Pluripotency of mesenchymal stem cells derived from adult marrow
    • Jiang Y, Jahagirdar BN, Reinhardt RL et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002;418:41-49.
    • (2002) Nature , vol.418 , pp. 41-49
    • Jiang, Y.1    Jahagirdar, B.N.2    Reinhardt, R.L.3
  • 2
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • Pittenger MF, Mackay AM, Beck SC et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999;284:143-147.
    • (1999) Science , vol.284 , pp. 143-147
    • Pittenger, M.F.1    Mackay, A.M.2    Beck, S.C.3
  • 3
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for nonhematopoietic tissues
    • Prockop DJ. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 1997;276:71-74.
    • (1997) Science , vol.276 , pp. 71-74
    • Prockop, D.J.1
  • 5
    • 0029000896 scopus 로고
    • Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice
    • Pereira RF, Halford KW, O'Hara MD et al. Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice. Proc Natl Acad Sci U S A 1995;92:4857-4861.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 4857-4861
    • Pereira, R.F.1    Halford, K.W.2    O'Hara, M.D.3
  • 8
    • 33646173257 scopus 로고    scopus 로고
    • Allogenic peripheral blood derived mesenchymal stem cells (MSCs) enhance bone regeneration in rabbit ulna critical-sized bone defect model
    • Wan C, He Q, Li G. Allogenic peripheral blood derived mesenchymal stem cells (MSCs) enhance bone regeneration in rabbit ulna critical-sized bone defect model. J Orthop Res 2006;24:610-618.
    • (2006) J Orthop Res , vol.24 , pp. 610-618
    • Wan, C.1    He, Q.2    Li, G.3
  • 9
    • 0024256133 scopus 로고
    • Novel regulators of bone formation: Molecular clones and activities
    • Wozney JM, Rosen V, Celeste AJ et al. Novel regulators of bone formation: Molecular clones and activities. Science 1988;242:1528-1534.
    • (1988) Science , vol.242 , pp. 1528-1534
    • Wozney, J.M.1    Rosen, V.2    Celeste, A.J.3
  • 10
    • 0023755311 scopus 로고
    • Ectopic bone induction on and in porous hydroxyapatite combined with collagen and bone morphogenetic protein
    • Takaoka K, Nakahara H, Yoshikawa H et al. Ectopic bone induction on and in porous hydroxyapatite combined with collagen and bone morphogenetic protein. Clin Orthop Relat Res 1988:250-254.
    • (1988) Clin Orthop Relat Res , pp. 250-254
    • Takaoka, K.1    Nakahara, H.2    Yoshikawa, H.3
  • 11
    • 33846498515 scopus 로고    scopus 로고
    • Bone marrow-derived osteoblast progenitor cells in circulating blood contribute to ectopic bone formation in mice
    • Otsuru S, Tamai K, Yamazaki T et al. Bone marrow-derived osteoblast progenitor cells in circulating blood contribute to ectopic bone formation in mice. Biochem Biophys Res Commun 2007;354:453-458.
    • (2007) Biochem Biophys Res Commun , vol.354 , pp. 453-458
    • Otsuru, S.1    Tamai, K.2    Yamazaki, T.3
  • 12
    • 0030904130 scopus 로고    scopus 로고
    • Green mice' as a source of ubiquitous green cells
    • Okabe M, Ikawa M, Kominami K et al. 'Green mice' as a source of ubiquitous green cells. FEBS Lett 1997;407:313-319.
    • (1997) FEBS Lett , vol.407 , pp. 313-319
    • Okabe, M.1    Ikawa, M.2    Kominami, K.3
  • 13
    • 0035976526 scopus 로고    scopus 로고
    • Physiological migration of hematopoietic stem and progenitor cells
    • Wright DE, Wagers AJ, Gulati AP et al. Physiological migration of hematopoietic stem and progenitor cells. Science 2001;294:1933-1936.
    • (2001) Science , vol.294 , pp. 1933-1936
    • Wright, D.E.1    Wagers, A.J.2    Gulati, A.P.3
  • 14
    • 0036155461 scopus 로고    scopus 로고
    • Involvement of phosphodiesterase isozymes in osteoblastic differentiation
    • Wakabayashi S, Tsutsumimoto T, Kawasaki S et al. Involvement of phosphodiesterase isozymes in osteoblastic differentiation. J Bone Miner Res 2002;17:249-256.
    • (2002) J Bone Miner Res , vol.17 , pp. 249-256
    • Wakabayashi, S.1    Tsutsumimoto, T.2    Kawasaki, S.3
  • 15
    • 0036133113 scopus 로고    scopus 로고
    • Novel hydroxyapatite ceramics with an interconnective porous structure exhibit superior osteoconduction in vivo
    • Tamai N, Myoui A, Tomita T et al. Novel hydroxyapatite ceramics with an interconnective porous structure exhibit superior osteoconduction in vivo. J Biomed Mater Res 2002;59:110-117.
    • (2002) J Biomed Mater Res , vol.59 , pp. 110-117
    • Tamai, N.1    Myoui, A.2    Tomita, T.3
  • 16
    • 4444372639 scopus 로고    scopus 로고
    • Bone tissue engineering using novel interconnected porous hydroxyapatite ceramics combined with marrow mesenchymal cells: Quantitative and three-dimensional image analysis
    • Nishikawa M, Myoui A, Ohgushi H et al. Bone tissue engineering using novel interconnected porous hydroxyapatite ceramics combined with marrow mesenchymal cells: Quantitative and three-dimensional image analysis. Cell Transplant 2004;13:367-376.
    • (2004) Cell Transplant , vol.13 , pp. 367-376
    • Nishikawa, M.1    Myoui, A.2    Ohgushi, H.3
  • 17
    • 31444455331 scopus 로고    scopus 로고
    • The effect of simulated microgravity by three-dimensional clinostat on bone tissue engineering
    • Nishikawa M, Ohgushi H, Tamai N et al. The effect of simulated microgravity by three-dimensional clinostat on bone tissue engineering. Cell Transplant 2005;14:829-835.
    • (2005) Cell Transplant , vol.14 , pp. 829-835
    • Nishikawa, M.1    Ohgushi, H.2    Tamai, N.3
  • 18
    • 0030064334 scopus 로고    scopus 로고
    • Receptor-ligand interaction between CD44 and osteopontin (Eta-1)
    • Weber GF, Ashkar S, Glimcher MJ et al. Receptor-ligand interaction between CD44 and osteopontin (Eta-1). Science 1996;271:509-512.
    • (1996) Science , vol.271 , pp. 509-512
    • Weber, G.F.1    Ashkar, S.2    Glimcher, M.J.3
  • 19
    • 0029775576 scopus 로고    scopus 로고
    • The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
    • Bleul CC, Farzan M, Choe H et al. The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 1996;382:829-833.
    • (1996) Nature , vol.382 , pp. 829-833
    • Bleul, C.C.1    Farzan, M.2    Choe, H.3
  • 20
    • 27144443385 scopus 로고    scopus 로고
    • Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells
    • Dar A, Goichberg P, Shinder V et al. Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells. Nat Immunol 2005;6:1038-1046.
    • (2005) Nat Immunol , vol.6 , pp. 1038-1046
    • Dar, A.1    Goichberg, P.2    Shinder, V.3
  • 21
    • 0033119201 scopus 로고    scopus 로고
    • The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment
    • Ma Q, Jones D, Springer TA. The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment. Immunity 1999;10:463-471.
    • (1999) Immunity , vol.10 , pp. 463-471
    • Ma, Q.1    Jones, D.2    Springer, T.A.3
  • 22
    • 0029758113 scopus 로고    scopus 로고
    • Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1
    • Nagasawa T, Hirota S, Tachibana K et al. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature 1996;382:635-638.
    • (1996) Nature , vol.382 , pp. 635-638
    • Nagasawa, T.1    Hirota, S.2    Tachibana, K.3
  • 23
    • 4043184065 scopus 로고    scopus 로고
    • Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
    • Ceradini DJ, Kulkarni AR, Callaghan MJ et al. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat Med 2004;10:858-864.
    • (2004) Nat Med , vol.10 , pp. 858-864
    • Ceradini, D.J.1    Kulkarni, A.R.2    Callaghan, M.J.3
  • 24
    • 0038024047 scopus 로고    scopus 로고
    • Expression of functional CXCR4 by muscle satellite cells and secretion of SDF-1 by muscle-derived fibroblasts is associated with the presence of both muscle progenitors in bone marrow and hematopoietic stem/progenitor cells in muscles
    • Ratajczak MZ, Majka M, Kucia M et al. Expression of functional CXCR4 by muscle satellite cells and secretion of SDF-1 by muscle-derived fibroblasts is associated with the presence of both muscle progenitors in bone marrow and hematopoietic stem/progenitor cells in muscles. STEM CELLS 2003;21:363-371.
    • (2003) STEM CELLS , vol.21 , pp. 363-371
    • Ratajczak, M.Z.1    Majka, M.2    Kucia, M.3
  • 25
    • 1842404184 scopus 로고    scopus 로고
    • Detection of stromal cells in peripheral blood progenitor cell collections from breast cancer patients
    • Fernandez M, Simon V, Herrera G et al. Detection of stromal cells in peripheral blood progenitor cell collections from breast cancer patients. Bone Marrow Transplant 1997;20:265-271.
    • (1997) Bone Marrow Transplant , vol.20 , pp. 265-271
    • Fernandez, M.1    Simon, V.2    Herrera, G.3
  • 27
    • 0031733871 scopus 로고    scopus 로고
    • Expression of bone morphogenetic proteins in fracture healing
    • Bostrom MP. Expression of bone morphogenetic proteins in fracture healing. Clin Orthop Relat Res 1998:S116-S123.
    • (1998) Clin Orthop Relat Res
    • Bostrom, M.P.1
  • 28
    • 0029008655 scopus 로고
    • Immunolocalization and expression of bone morphogenetic proteins 2 and 4 in fracture healing
    • Bostrom MP, Lane JM, Berberian WS et al. Immunolocalization and expression of bone morphogenetic proteins 2 and 4 in fracture healing. J Orthop Res 1995;13:357-367.
    • (1995) J Orthop Res , vol.13 , pp. 357-367
    • Bostrom, M.P.1    Lane, J.M.2    Berberian, W.S.3
  • 29
    • 0028787830 scopus 로고
    • Enhanced expression of type I receptors for bone morphogenetic proteins during bone formation
    • Ishidou Y, Kitajima I, Obama H et al. Enhanced expression of type I receptors for bone morphogenetic proteins during bone formation. J Bone Miner Res 1995;10:1651-1659.
    • (1995) J Bone Miner Res , vol.10 , pp. 1651-1659
    • Ishidou, Y.1    Kitajima, I.2    Obama, H.3
  • 30
    • 0030775766 scopus 로고    scopus 로고
    • Human bone marrow-derived mesenchymal (stromal) progenitor cells (MPCs) cannot be recovered from peripheral blood progenitor cell collections
    • Lazarus HM, Haynesworth SE, Gerson SL et al. Human bone marrow-derived mesenchymal (stromal) progenitor cells (MPCs) cannot be recovered from peripheral blood progenitor cell collections. J Hematother 1997;6:447-455.
    • (1997) J Hematother , vol.6 , pp. 447-455
    • Lazarus, H.M.1    Haynesworth, S.E.2    Gerson, S.L.3
  • 31
    • 0037541500 scopus 로고    scopus 로고
    • Adult bone marrow is a rich source of human mesenchymal 'stem' cells but umbilical cord and mobilized adult blood are not
    • Wexler SA, Donaldson C, Denning-Kendall P et al. Adult bone marrow is a rich source of human mesenchymal 'stem' cells but umbilical cord and mobilized adult blood are not. Br J Haematol 2003;121:368-374.
    • (2003) Br J Haematol , vol.121 , pp. 368-374
    • Wexler, S.A.1    Donaldson, C.2    Denning-Kendall, P.3
  • 32
    • 0029906582 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin
    • Nagasawa T, Nakajima T, Tachibana K et al. Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin. Proc Natl Acad Sci U S A 1996;93:14726-14729.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 14726-14729
    • Nagasawa, T.1    Nakajima, T.2    Tachibana, K.3
  • 33
    • 0034468279 scopus 로고    scopus 로고
    • Mesenchymal precursor cells in the blood of normal individuals
    • Zvaifler NJ, Marinova-Mutafchieva L, Adams G et al. Mesenchymal precursor cells in the blood of normal individuals. Arthritis Res 2000;2:477-488.
    • (2000) Arthritis Res , vol.2 , pp. 477-488
    • Zvaifler, N.J.1    Marinova-Mutafchieva, L.2    Adams, G.3
  • 34
    • 0031026475 scopus 로고    scopus 로고
    • The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood
    • Aiuti A, Webb IJ, Bleul C et al. The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood. J Exp Med 1997;185:111-120.
    • (1997) J Exp Med , vol.185 , pp. 111-120
    • Aiuti, A.1    Webb, I.J.2    Bleul, C.3
  • 35
    • 0029833943 scopus 로고    scopus 로고
    • A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)
    • Bleul CC, Fuhlbrigge RC, Casasnovas JM et al. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1). J Exp Med 1996;184:1101-1109.
    • (1996) J Exp Med , vol.184 , pp. 1101-1109
    • Bleul, C.C.1    Fuhlbrigge, R.C.2    Casasnovas, J.M.3
  • 36
    • 30344437303 scopus 로고    scopus 로고
    • VEGF-induced adult neovascularization: Recruitment, retention, and role of accessory cells
    • Grunewald M, Avraham I, Dor Y et al. VEGF-induced adult neovascularization: Recruitment, retention, and role of accessory cells. Cell 2006;124:175-189.
    • (2006) Cell , vol.124 , pp. 175-189
    • Grunewald, M.1    Avraham, I.2    Dor, Y.3
  • 37
    • 19944426191 scopus 로고    scopus 로고
    • Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway
    • Imitola J, Raddassi K, Park KI et al. Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway. Proc Natl Acad Sci U S A 2004;101:18117-18122.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 18117-18122
    • Imitola, J.1    Raddassi, K.2    Park, K.I.3
  • 38
    • 2942555661 scopus 로고    scopus 로고
    • Interactions of chemokines and chemokine receptors mediate the migration of mesenchymal stem cells to the impaired site in the brain after hypoglossal nerve injury
    • Ji JF, He BP, Dheen ST et al. Interactions of chemokines and chemokine receptors mediate the migration of mesenchymal stem cells to the impaired site in the brain after hypoglossal nerve injury. STEM CELLS 2004;22:415-427.
    • (2004) STEM CELLS , vol.22 , pp. 415-427
    • Ji, J.F.1    He, B.P.2    Dheen, S.T.3
  • 39
    • 0027937391 scopus 로고
    • Localization of the mRNA for bone matrix proteins during fracture healing as determined by in situ hybridization
    • Hirakawa K, Hirota S, Ikeda T et al. Localization of the mRNA for bone matrix proteins during fracture healing as determined by in situ hybridization. J Bone Miner Res 1994;9:1551-1557.
    • (1994) J Bone Miner Res , vol.9 , pp. 1551-1557
    • Hirakawa, K.1    Hirota, S.2    Ikeda, T.3
  • 40
    • 0033029158 scopus 로고    scopus 로고
    • Spatial and temporal distribution of CD44 and osteopontin in fracture callus
    • Yamazaki M, Nakajima F, Ogasawara A et al. Spatial and temporal distribution of CD44 and osteopontin in fracture callus. J Bone Joint Surg Br 1999;81:508-515.
    • (1999) J Bone Joint Surg Br , vol.81 , pp. 508-515
    • Yamazaki, M.1    Nakajima, F.2    Ogasawara, A.3
  • 41
    • 33749529321 scopus 로고    scopus 로고
    • Multipotential mesenchymal stem cells are mobilized into peripheral blood by hypoxia
    • Rochefort GY, Delorme B, Lopez A et al. Multipotential mesenchymal stem cells are mobilized into peripheral blood by hypoxia. STEM CELLS 2006;24:2202-2208.
    • (2006) STEM CELLS , vol.24 , pp. 2202-2208
    • Rochefort, G.Y.1    Delorme, B.2    Lopez, A.3
  • 42
    • 0033105596 scopus 로고    scopus 로고
    • Augmentation of spinal arthrodesis with autologous bone marrow in a rabbit posterolateral spine fusion model
    • discussion 438-439
    • Curylo LJ, Johnstone B, Petersilge CA et al. Augmentation of spinal arthrodesis with autologous bone marrow in a rabbit posterolateral spine fusion model. Spine 1999;24:434-438; discussion 438-439.
    • (1999) Spine , vol.24 , pp. 434-438
    • Curylo, L.J.1    Johnstone, B.2    Petersilge, C.A.3
  • 43
    • 0026318653 scopus 로고
    • Autogeneic bone marrow and porous biphasic calcium phosphate ceramic for segmental bone defects in the canine ulna
    • Grundel RE, Chapman MW, Yee T et al. Autogeneic bone marrow and porous biphasic calcium phosphate ceramic for segmental bone defects in the canine ulna. Clin Orthop Relat Res 1991:244-258.
    • (1991) Clin Orthop Relat Res , pp. 244-258
    • Grundel, R.E.1    Chapman, M.W.2    Yee, T.3
  • 44
    • 0020367405 scopus 로고
    • Extraskeletal and intraskeletal new bone formation induced by demineralized bone matrix combined with bone marrow cells
    • Lindholm TS, Nilsson OS, Lindholm TC. Extraskeletal and intraskeletal new bone formation induced by demineralized bone matrix combined with bone marrow cells. Clin Orthop Relat Res 1982:251-255.
    • (1982) Clin Orthop Relat Res , pp. 251-255
    • Lindholm, T.S.1    Nilsson, O.S.2    Lindholm, T.C.3
  • 45
    • 0023912957 scopus 로고
    • Response of bone marrow stroma cells to demineralized cortical bone matrix in experimental spinal fusion in rabbits
    • Lindholm TS, Ragni P, Lindholm TC. Response of bone marrow stroma cells to demineralized cortical bone matrix in experimental spinal fusion in rabbits. Clin Orthop Relat Res 1988:296-302.
    • (1988) Clin Orthop Relat Res , pp. 296-302
    • Lindholm, T.S.1    Ragni, P.2    Lindholm, T.C.3
  • 46
    • 0020420825 scopus 로고
    • The role of bone marrow in bone morphogenetic protein-induced repair of femoral massive diaphyseal defects
    • Takagi K, Urist MR. The role of bone marrow in bone morphogenetic protein-induced repair of femoral massive diaphyseal defects. Clin Orthop Relat Res 1982:224-231.
    • (1982) Clin Orthop Relat Res , pp. 224-231
    • Takagi, K.1    Urist, M.R.2
  • 47
    • 0029659155 scopus 로고    scopus 로고
    • Qualitative and quantitative analysis of orthotopic bone regeneration by marrow
    • Werntz JR, Lane JM, Burstein AH et al. Qualitative and quantitative analysis of orthotopic bone regeneration by marrow. J Orthop Res 1996;14:85-93.
    • (1996) J Orthop Res , vol.14 , pp. 85-93
    • Werntz, J.R.1    Lane, J.M.2    Burstein, A.H.3
  • 48
    • 10744222737 scopus 로고    scopus 로고
    • Gene targeting in stem cells from individuals with osteogenesis imperfecta
    • Chamberlain JR, Schwarze U, Wang PR et al. Gene targeting in stem cells from individuals with osteogenesis imperfecta. Science 2004;303:1198-1201.
    • (2004) Science , vol.303 , pp. 1198-1201
    • Chamberlain, J.R.1    Schwarze, U.2    Wang, P.R.3
  • 49
    • 0032976690 scopus 로고    scopus 로고
    • Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta
    • Horwitz EM, Prockop DJ, Fitzpatrick LA et al. Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta. Nat Med 1999;5:309-313.
    • (1999) Nat Med , vol.5 , pp. 309-313
    • Horwitz, E.M.1    Prockop, D.J.2    Fitzpatrick, L.A.3
  • 50
    • 0344961120 scopus 로고    scopus 로고
    • Murine marrow-derived mesenchymal stem cell: Isolation, in vitro expression, and characterization
    • Meirelles LS, Nardi NB. Murine marrow-derived mesenchymal stem cell: Isolation, in vitro expression, and characterization. Br J Haematol 2003;123:702-711.
    • (2003) Br J Haematol , vol.123 , pp. 702-711
    • Meirelles, L.S.1    Nardi, N.B.2
  • 51
    • 0043071544 scopus 로고    scopus 로고
    • Characterization of mesenchymal stem cells isolated from murine bone marrow by negative selection
    • Baddoo M, Hill K, Wilkinson R et al. Characterization of mesenchymal stem cells isolated from murine bone marrow by negative selection. J Cell Biochem 2003;89:1235-1249.
    • (2003) J Cell Biochem , vol.89 , pp. 1235-1249
    • Baddoo, M.1    Hill, K.2    Wilkinson, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.