TRANCE (Tumor necrosis factor [TNF]-related Activation-induced Cytokine), a new TNF family member predominantly expressed in t cells, is a dendritic cell-specific survival factor

Journal of Experimental Medicine

Volumn 186, Issue 12, 1997, Pages 2075-2080

  Wong, Brian R ^a   Josien, Régis ^a   Lee, Soo Young ^a   Sauter, Birthe ^a   Li, Hong Li ^a   Steinman, Ralph M ^a   Choi, Yongwon ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; DENDRITIC CELL; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; T LYMPHOCYTE;

ANIMALS; APOPTOSIS; B-LYMPHOCYTES; BCL-X PROTEIN; BONE MARROW CELLS; CARRIER PROTEINS; CD40 LIGAND; CELL SEPARATION; CELL SURVIVAL; CYTOKINES; DENDRITIC CELLS; FLOW CYTOMETRY; HUMANS; MEMBRANE GLYCOPROTEINS; MICE; MICE, TRANSGENIC; PROTO-ONCOGENE PROTEINS C-BCL-2; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; RNA, MESSENGER; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 0031439265     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.186.12.2075     Document Type: Article

References (32)

1. Wyllie, A.H. 1992. Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: an overview. Cancer Metastasis Rev. 11:95-103.
2. Russell, J.H. 1995. Activation-induced death of mature T cells in the regulation of immune responses. Curr. Opin. Immunol. 7:382-388.
3. Lynch, D.H., F. Ramsdell, and M.R. Alderson. 1995. Fas and FasL in the homeostatic regulation of immune responses. Immunol. Today. 16:569-574.
4. Smith, C.A., T. Farrah, and R.G. Goodwin. 1994. The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death. Cell. 76:959-962.
5. Rothe, M., S.C. Wong, W.J. Henzel, and D.V. Goeddel. 1994. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor. Cell. 78:681-692.
6. Rothe, M., V. Sarma, V.M. Dixit, and D.V. Goeddel. 1995. TRAF2-mediated activation of NF-κB by TNF receptor 2 and CD40. Science. 269:1424-1427.
7. Natoli, G., A. Costanzo, A. Ianni, D.J. Templeton, J.R. Woodgett, C. Balsano, and M. Levrero. 1997. Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway. Science. 275:200-203.
8. Reinhard, C., B. Shamoon, V. Shyamala, and L.T. Williams. 1997. Tumor necrosis factor α-induced activation of c-jun N-terminal kinase is mediated by TRAF2. EMBO (Eur. Mol. Biol. Organ.) J. 16:1080-1092.
9. Liu, Z.G., H. Hsu, D.V. Goeddel, and M. Karin. 1996. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death. Cell. 87:565-576.
10. Darnay, B.G., and B.B. Aggarwal. 1997. Early events in TNF signaling: a story of associations and dissociations. J. Leukocyte Biol. 61:559-566.
11. Baeuerle, P.A., and D. Baltimore. 1996. NF-κB: Ten years after. Cell. 87:13-20.
12. Bjorck, P., J. Banchereau, and R.L. Flores. 1997. CD40 ligation counteracts Fas-induced apoptosis of human dendritic cells. Int. Immunol. 9:365-372.
13. Wang, Z., J.G. Karras, R.G. Howard, and T.L. Rothstein. 1995. Induction of bcl-x by CD40 engagement rescues sIg-induced apoptosis in murine B cells. J. Immunol. 155:3722-3725.
14. L forms an ion channel in synthetic lipid membranes. Nature. 385:353-357.
15. Chinnaiyan, A.M., K. O'Rourke, B.R. Lane, and V.M. Dixit. 1997. Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death. Science. 275:1122-1126.
16. xL function upstream of the CED-3-like apoptotic proteases. J. Biol. Chem. 271:4573-4576.
17. Steinman, R.M. 1991. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 9:271-296.
18. + hematopoietic progenitors induces their proliferation and differentiation into functional dendritic cells. J. Exp. Med. 185:341-349.
19. + TNFα. J. Exp. Med. 184:695-706.
20. + bone marrow progenitors that are expanded by c-kit-ligand and yield pure dendritic cell colonies in the presence of granulocyte/macrophage colony-stimulating factor and tumor necrosis factor α. J. Exp. Med. 182:1111-1119.
21. van Kooten, C., and J. Banchereau. 1997. Functions of CD40 on B cells, dendritic cells and other cells. Curr. Opin. Immunol. 3:330-337.
22. Wong, B., J. Rho, J. Arron, E. Robinson, J. Orlinick, M. Chao, S. Kalachikov, E. Cayani, F.S. Bartlett III, W. Frankel, et al. 1997. TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells. J. Biol. Chem. 372:25190-25194.
23. Lee, S., A. Reichlin, A. Santana, K. Sokol, M. Nussenzweig, and Y. Choi. 1997. TRAF2 is essential for JNK but not NF-κB activation and regulates lymphocyte proliferation and survival. Immunity. In press.
24. Inaba, K., M. Inaba, N. Romani, H. Aya, M. Deguchi, S. Ikehara, S. Muramatsu, and R.M. Steinman. 1992. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176:1693-1702.
25. Steinman, R.M., G. Kaplan, M.D. Witmer, and Z.A. Cohn. 1979. Identification of a novel cell type in peripheral lymphoid organs of mice. V. Purification of spleen dendritic cells, new surface markers, and maintenance in vitro. J. Exp. Med. 144:1-16.
26. Bender, A., M. Sapp, G. Schuler, R.M. Steinman, and N. Bhardwaj. 1996. Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood. J. Immunol. Methods. 196:121-135.
27. 2+-dependent mechanism. J. Exp. Med. 186:467-472.
28. Caux, C., C. Massacrier, U. Vanbervliet, B. Dubois, C. Kootan, I. Durand, and J. Banchereau. 1994. Activation of human dendritic cells through CD40 cross-linking. J. Exp. Med. 180:1263-1272.
29. Ludewig, B., D. Graf, H. Gelderblom, Y. Becker, R. Kroczek, and G. Pauli. 1995. Spontaneous apoptosis of dendritic cells is inhibited by TRAP (CD40-ligand) and TNF-α, but strongly enhanced by interleukin-10. Eur. J. Immunol. 25:1943-1950.
30. Granelli, P.A., M. Pope, K. Inaba, and R.M. Steinman. 1995. Coexpression of NF-κB/Rel and Sp1 transcription factors in human immunodeficiency virus 1-induced, dendritic cell-T-cell syncytia. Proc. Natl. Acad. Sci. USA. 92:10944-10948.
31. Steinman, R.M., M. Pack, and K. Inaba. 1997. Dendritic cells in the T-cell areas of lymphoid organs. Immunol. Rev. 156:25-37.
32. Young, J.W., and K. Inaba. 1996. Dendritic cells as adjuvants for class I major histocompatibility complex-restricted antitumor immunity. J. Exp. Med. 183:7-11.