Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

Cell

Volumn 93, Issue 2, 1998, Pages 165-176

  Lacey, D L ^a   Timms, E ^a   Tan, H L ^a   Kelley, M J ^a   Dunstan, C R ^a   Burgess, T ^a   Elliott, R ^a   Colombero, A ^a   Elliott, G ^a   Scully, S ^a   Hsu, H ^a   Sullivan, J ^a   Hawkins, N ^a   Davy, E ^a   Capparelli, C ^a   Eli, A ^a   Qian, Y X ^a   Kaufman, S ^a   Sarosi, I ^a   Shalhoub, V ^a   Senaldi, G ^a   Guo, J ^a   Delaney, J ^a   Boyle, W J ^a   more..

^a AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; LIGAND; OSTEOPROTEGERIN; RECEPTOR PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYPERCALCEMIA; LIGAND BINDING; MALE; MOUSE; NONHUMAN; OSTEOCLAST; PRIORITY JOURNAL;

ANIMALIA;

EID: 0032540319     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81569-X     Document Type: Article

References (24)

1. Abe, E., Tanaka, H., Ishimi, Y., Miyaura, C., Hayashi, T., Nagasawa, H., Tomida, M., Yamaguchi, Y., Hozumi, M., and Suda, T. (1986). Differentiation-inducing factor purified from conditioned medium of mitogen-treated spleen cell cultures stimulates bone resorption. Proc. Natl. Acad. Sci. USA 83, 5958-5962.
2. Anderson, D.M., Maraskovsky, E., Billinglsey, W.L., Dougall, W.C., Tometsko, M.E., Roux, E.R., Teepe, M.C., DuBose, R.F., Cosman, D., and Galibert, L. (1997). A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature 390, 175-179.
3. Arnett, T.R., and Dempster, D.W. (1986). Effect of pH on bone resorption by rat osteoclasts in vitro. Endocrinology 119, 119-124.
4. Banner, D.W., D'Arcy, A., Janes, W., Gentz, R., Schoenfeld, H.-J., Broger, C., Loetscher, H., and Lesslauer, W. (1993). Crystal structure of the soluble human 55 kd TNF receptor-human TNFb complex: implications for TNF receptor activation. Cell 73, 431-445.
5. Bartley, T.D., Hunt, R.W., Welcher, A.A., Boyle, W.J., Parker, V.P., Lindberg, R.A., Lu, H.S., Colombero, A.M., Elliott, R.L., Guthrie, B.A., et al. (1994). B61 is a ligand for the ECK receptor protein-tyrosine kinase. Nature 368, 558-560.
6. Chen, P.C.-H., DuBois, G.C., and Chen, M.-J. (1995). Mapping the domain(s) critical for the binding of human tumor necrosis factor-α to its two receptors. J. Biol. Chem. 270, 2874-2878.
7. Chinnaiyan, A.M., O'Rourke, K., Yu, G.L., Lyons, R.H., Garg, M., Duan, D.R., Xing, L., Gentz., R., Ni, J., and Dixit, V.M. (1996). Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95. Science 274, 990-992.
8. Evans, R.A., Dunstan, C.R., and Baylink, D.J. (1979). Histochemical identification of osteoclasts in undecalcified sections of human bone. Mineral Electolyte Metab. 2, 179-185.
9. Fuller, K., Gallagher, A.C., and Chambers, T.J. (1991). Osteoclast resorption-stimulating activity is associated with the osteoblast cell surface and/or the extracellular matrix. Biochem. Biophys. Res. Commun. 181, 67-73.
10. Hentunen, T.A., Cunningham, N.S., Vuolteenaho, O., Reddi, A.H., and Vaananen, H.K. (1994). Osteoclast recruiting activity in bone matrix. Bone Min. 25, 183-198.
11. Norton, J.E. (1972). Bone resorbing activity in supernatant fluid from cultured human periperhal blood leukocytes. Science 177, 793-795.
12. Hsu, H., Solovyev, I., Colombero, A., Elliott, R., Kelley, M., and Boyle, W.J. (1997). ATAR, a novel tumor necrosis factor receptor family member, signals through TRAF2 and TRAF5. J. Biol. Chem. 272, 13471-13474.
13. Lacey, D.L., Erdmann, J.M., Teitelbaum, S.L., Tan, H.-L., O'Hara, J., and Shioi, A. (1995). Interleukin 4, Interferon-γ, and prostaglandin E impact the osteoclastic cell-forming potential of murine bone marrow macrophages. Endocrinology 136, 2367-2376.
14. Lee, M.Y., Eyre, D.R., and Osborne, W.R.A. (1991). Isolation of a murine osteoclast colony-stimulating factor. Proc. Natl. Acad. Sci. USA 88, 8500-8504.
15. Pitti, R.M., Marsters, S.A., Ruppert, S., Donahue, C.J., Moore, A., and Ashkenazi, A. (1996). Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J. Biol. Chem. 271, 12687-12690.
16. Simonet, W.S., Lacey, D.L., Dunstan, C.R., Kelley, M., Chang, M.-S., Luthy, R., Nguyen, H.Q., Wooden, S., Bennett, L., Boone, T., et al. (1997). Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 89, 309-319.
17. Suda, T., Takahashi, N., and Martin, T.J. (1992). Modulation of osteoclast differentiation. Endocr. Rev. 13, 66-80.
18. Takahashi, N., Yamana, H., Yoshiki, S., Roodman, G.D., Mundy, G.R., Jones, S.J., Boyde, A., and Suda, T. (1988). Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures. Endocrinology 122, 1373-1382.
19. Udagawa, N., Chan, J., Wada, S., Findlay, D.M., Hamilton, J.A., and Martin, T.J. (1996). c-fos antisense DNA inhibits proliferation of osteoclast progenitors in osteoclast development but not macrophage differentiation in vitro. Bone 18, 511-516.
20. Wilcox, J.N. (1993). Fundamental principles of in situ hybridization. J. Histochem. Cytochem. 41, 1725-1733.
21. Wiley, S.R., Schooley, K., Smolak, P.J., Din, W.S., Huang, C.-P., Nicholl, J.K., Sutherland, G.R., Smith, T.D., Rauch, C., Smith, C.A., and Goodwin, R.G. (1995). Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3, 673-682.
22. Wilson, C.A., Payton, M.N., Elliott, G.S., Buuas, F.W., Cajulis, E.E., Grosshans, D., Ramos, L., Reese, D.M., Slamon, D.J., and Calzone, F.J. (1997). Differential subcellular localization, expression and biological toxicity of BRAC1 and the splice varient BRAC1-D11B. Oncogene 14, 1-16.
23. Wong, B.R., Rho, J., Arron, J., Robinson, E., Orlinick, J., Chao, M., Kalachikov, S., Cayani, E., Bartlett, F.S., III., Frankel, W.N., Lee, S.Y., and Choi, Y. (1997). TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells. J. Biol. Chem. 272, 25190-25194.
24. Yoneda, T., Kato, I., Bonewald, L.F., Burgess, W.H., and Mundy, G.R. (1993). A novel cytokine with osteoclastopoietic activity. J. Periodontal Res. 28, 521-522.