Global gene profiling reveals a downregulation of BMP gene expression in experimental atrophic nonunions compared to standard healing fractures

Journal of Orthopaedic Research

Volumn 24, Issue 7, 2006, Pages 1463-1471

  Niikura, Takahiro ^a   Hak, David J ^a   Hari Reddi, A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

BMP antagonists; Bone morphogenetic proteins; Fracture healing; Gene expression; Nonunion

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 12; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 6; BONE MORPHOGENETIC PROTEIN AND ACTIVIN MEMBRANE BOUND INHIBITOR; COMPLEMENTARY DNA; DRM PROTEIN; GREMLIN 1 HOMOLOG PROTEIN; GROWTH DIFFERENTIATION FACTOR 5; MESSENGER RNA; NOGGIN; OSTEOGENIC PROTEIN 1; OSTEOGENIN; OSTEOGENIN B; PROTEIN DERIVATIVE; SCRELOSTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; CALLUS; CAUTERIZATION; CONTROLLED STUDY; DOWN REGULATION; FEMUR SHAFT FRACTURE; FRACTURE HEALING; FRACTURE NONUNION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MALE; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIOSTEUM; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION;

ANIMALS; BONE MORPHOGENETIC PROTEINS; CARRIER PROTEINS; DOWN-REGULATION; FEMORAL FRACTURES; FRACTURE HEALING; FRACTURES, CLOSED; FRACTURES, UNUNITED; GENE EXPRESSION PROFILING; GENETIC MARKERS; GLYCOPROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, LONG-EVANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 33746134510     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20182     Document Type: Article

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