Zfp521 antagonizes Runx2, delays osteoblast differentiation in vitro, and promotes bone formation in vivo

Bone

Volumn 44, Issue 4, 2009, Pages 528-536

  Wu, Meilin ^a,c   Hesse, Eric ^a,b   Morvan, Frederic ^a,d   Zhang, Jian Ping ^a   Correa, Diego ^a,b   Rowe, Glenn C ^a,b   Kiviranta, Riku ^a,b   Neff, Lynn ^a   Philbrick, William M ^a   Horne, William C ^a,b   Baron, Roland ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

^c Molecular Cardiology Research Center   (United States)

^d NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Bone formation; Differentiation; Osteoblast; Runx2; Zfp521

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; OSTEOCALCIN; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN 521;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MASS; CARTILAGE CELL; CELL DIFFERENTIATION; COMPETITIVE INHIBITION; CONTROLLED STUDY; GENE OVEREXPRESSION; GENETIC MARKER; GENETIC TRANSCRIPTION; IN VITRO STUDY; IN VIVO STUDY; MESENCHYME CELL; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; PERICHONDRIUM; PERIOSTEUM; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION;

ANIMALS; BLOTTING, NORTHERN; CELL DIFFERENTIATION; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DNA-BINDING PROTEINS; FLUORESCENT ANTIBODY TECHNIQUE; IN SITU HYBRIDIZATION; MICE; MICE, TRANSGENIC; OSTEOBLASTS; OSTEOGENESIS; PROTO-ONCOGENES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 61849130657     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2008.11.011     Document Type: Article

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