-
1
-
-
0026030199
-
Biochemical mechanisms of MPTP toxicity
-
Adams J.D., Odunze I.N. Biochemical mechanisms of MPTP toxicity. Biochem Pharmaco 1991, 41:1099-1105.
-
(1991)
Biochem Pharmaco
, vol.41
, pp. 1099-1105
-
-
Adams, J.D.1
Odunze, I.N.2
-
2
-
-
0037349612
-
The Southeast Collaboratory for Structural Genomics: a high-throughput gene to structure factory
-
Adams M.W., Dailey H.A., DeLucas L.J., Luo M., Prestegard J.H., Rose J.P., Wang B.C. The Southeast Collaboratory for Structural Genomics: a high-throughput gene to structure factory. Acc Chem Res 2003, 36:191-198.
-
(2003)
Acc Chem Res
, vol.36
, pp. 191-198
-
-
Adams, M.W.1
Dailey, H.A.2
DeLucas, L.J.3
Luo, M.4
Prestegard, J.H.5
Rose, J.P.6
Wang, B.C.7
-
3
-
-
0031194076
-
A Cdc42 target protein with homology to the nonkinase domain of FER has a potential role in regulating the actin cytoskeleton
-
Aspenstrom P. A Cdc42 target protein with homology to the nonkinase domain of FER has a potential role in regulating the actin cytoskeleton. Curr Biol 1997, 7:479-487.
-
(1997)
Curr Biol
, vol.7
, pp. 479-487
-
-
Aspenstrom, P.1
-
4
-
-
0142135452
-
Dopamine transmission in DYT1 dystonia
-
Lippincott Williams & Wilkins Publishers, Philadelphia, S. Fahn, M.A. Hallet, M.R. De Long (Eds.)
-
Augood S.J., Hollingsworth Z., Albers D.S., Yang L., Leung J.C., Breakefield X.O., Standaert D.G. Dopamine transmission in DYT1 dystonia. Dystonia 4: Advances in Neurology 2003, 53-60. Lippincott Williams & Wilkins Publishers, Philadelphia. S. Fahn, M.A. Hallet, M.R. De Long (Eds.).
-
(2003)
Dystonia 4: Advances in Neurology
, pp. 53-60
-
-
Augood, S.J.1
Hollingsworth, Z.2
Albers, D.S.3
Yang, L.4
Leung, J.C.5
Breakefield, X.O.6
Standaert, D.G.7
-
5
-
-
0032754787
-
Distribution of the mRNAs encoding torsin A and torsinB in the normal adult human brain
-
Augood S.J., Martin D.M., Ozelius L.J., Breakefield X.O., Penney J.B., Standaert D.G. Distribution of the mRNAs encoding torsin A and torsinB in the normal adult human brain. Ann Neurol 1999, 46:761-769.
-
(1999)
Ann Neurol
, vol.46
, pp. 761-769
-
-
Augood, S.J.1
Martin, D.M.2
Ozelius, L.J.3
Breakefield, X.O.4
Penney, J.B.5
Standaert, D.G.6
-
6
-
-
0036468432
-
Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease
-
Auluck P.K., Chan H.Y., Trojanowski J.Q., Lee V.M., Bonini N.M. Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science 2002, 295:865-868.
-
(2002)
Science
, vol.295
, pp. 865-868
-
-
Auluck, P.K.1
Chan, H.Y.2
Trojanowski, J.Q.3
Lee, V.M.4
Bonini, N.M.5
-
7
-
-
0032509484
-
Neurobiology of the Caenorhabditis elegans genome
-
Bargmann C.I. Neurobiology of the Caenorhabditis elegans genome. Science 1998, 282:2028-2033.
-
(1998)
Science
, vol.282
, pp. 2028-2033
-
-
Bargmann, C.I.1
-
8
-
-
0033571036
-
Mutations in ooc-5 and ooc-3 disrupt oocyte formation and the reestablishment of asymmetric PAR protein localization in two-cell Caenorhabditis elegans embryos
-
Basham S.E., Rose L.S. Mutations in ooc-5 and ooc-3 disrupt oocyte formation and the reestablishment of asymmetric PAR protein localization in two-cell Caenorhabditis elegans embryos. Dev Biol 1999, 215:253-263.
-
(1999)
Dev Biol
, vol.215
, pp. 253-263
-
-
Basham, S.E.1
Rose, L.S.2
-
9
-
-
0035202870
-
The Caenorhabditis elegans polarity gene ooc-5 encodes a torsin-related protein of the AAA+ATPase superfamily
-
Basham S.E., Rose L.S. The Caenorhabditis elegans polarity gene ooc-5 encodes a torsin-related protein of the AAA+ATPase superfamily. Development 2001, 28:4645-4656.
-
(2001)
Development
, vol.28
, pp. 4645-4656
-
-
Basham, S.E.1
Rose, L.S.2
-
10
-
-
0038051345
-
Mitochondria, oxidative damage and inflammation in Parkinson's disease
-
Beal M.F. Mitochondria, oxidative damage and inflammation in Parkinson's disease. Ann N Y Acad Sci 2003, 991:120-131.
-
(2003)
Ann N Y Acad Sci
, vol.991
, pp. 120-131
-
-
Beal, M.F.1
-
11
-
-
0025372762
-
The MPTP model: versatile contributions to the treatment of idiopathic Parkinson's disease
-
Bloem B.R., Irwin I., Buruma O.F., Hann J., Roos F.A., Tetrud J.W., Langston J.W. The MPTP model: versatile contributions to the treatment of idiopathic Parkinson's disease. J Neurol Sci 1990, 97:273-293.
-
(1990)
J Neurol Sci
, vol.97
, pp. 273-293
-
-
Bloem, B.R.1
Irwin, I.2
Buruma, O.F.3
Hann, J.4
Roos, F.A.5
Tetrud, J.W.6
Langston, J.W.7
-
12
-
-
0037142086
-
A global analysis of Caenorhabditis elegans operons
-
Blumenthal T., Evans D., Link C.D., Guffanti A., Lawson D., Thierry-Mieg J., Thierry-Mieg D., et al. A global analysis of Caenorhabditis elegans operons. Nature 2002, 417:851-854.
-
(2002)
Nature
, vol.417
, pp. 851-854
-
-
Blumenthal, T.1
Evans, D.2
Link, C.D.3
Guffanti, A.4
Lawson, D.5
Thierry-Mieg, J.6
Thierry-Mieg, D.7
-
13
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
Bonifati V., Rizzu P., van Baren M.J., Schaap O., Breedveld G.J., Krieger E., Dekker M.C., et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 2003, 299:256-259.
-
(2003)
Science
, vol.299
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
van Baren, M.J.3
Schaap, O.4
Breedveld, G.J.5
Krieger, E.6
Dekker, M.C.7
-
14
-
-
0035978884
-
Insulin-like signaling, metabolism, stress resistance and aging in C. elegans
-
Braeckman B.P., Houthoofd K., Vanfleteren J.R. Insulin-like signaling, metabolism, stress resistance and aging in C. elegans. Mech Ageing Dev 2001, 122:673-693.
-
(2001)
Mech Ageing Dev
, vol.122
, pp. 673-693
-
-
Braeckman, B.P.1
Houthoofd, K.2
Vanfleteren, J.R.3
-
15
-
-
0016063911
-
The genetics of Caenorhabditis elegans
-
Brenne S. The genetics of Caenorhabditis elegans. Genetics 1974, 77:71-94.
-
(1974)
Genetics
, vol.77
, pp. 71-94
-
-
Brenne, S.1
-
16
-
-
0142040246
-
Dystonia genotypes, phenotypes and classification
-
Lippincott Williams & Wilkins Publishers, Philadelphia, S. Fahn, M.A. Hallet, M.R. De Long (Eds.)
-
Bressman S.B. Dystonia genotypes, phenotypes and classification. Dystonia 4: Advances in Neurology 2003, 101-107. Lippincott Williams & Wilkins Publishers, Philadelphia. S. Fahn, M.A. Hallet, M.R. De Long (Eds.).
-
(2003)
Dystonia 4: Advances in Neurology
, pp. 101-107
-
-
Bressman, S.B.1
-
17
-
-
0032509302
-
C. elegans Sequencing Consortium Genome sequence of the nematode Caenorhabditis elegans: a platform for investigating biology
-
C. elegans Sequencing Consortium Genome sequence of the nematode Caenorhabditis elegans: a platform for investigating biology. Science 1998, 282:2012-2018.
-
(1998)
Science
, vol.282
, pp. 2012-2018
-
-
-
18
-
-
0037319121
-
Suppression of polyglutamine-induced protein aggregation in C. elegans by torsin proteins
-
Caldwell G.A., Cao S., Gelwix C.C., Sexton E.G., Bevel J.P., Caldwell K.A. Suppression of polyglutamine-induced protein aggregation in C. elegans by torsin proteins. Hum Mol Genet 2003, 12:307-319.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 307-319
-
-
Caldwell, G.A.1
Cao, S.2
Gelwix, C.C.3
Sexton, E.G.4
Bevel, J.P.5
Caldwell, K.A.6
-
19
-
-
0142103755
-
An animal model to discern torsin function: suppression of protein aggregation in C. elegans
-
Lippincott Williams & Wilkins Publishers, Philadelphia, S. Fahn, M.A. Hallet, M.R. De Long (Eds.)
-
Caldwell G.A., Cao S., Gelwix C.C., Sexton E.G., Caldwell K.A. An animal model to discern torsin function: suppression of protein aggregation in C. elegans. Dystonia 4: Advances in Neurology 2004, 79-85. Lippincott Williams & Wilkins Publishers, Philadelphia. S. Fahn, M.A. Hallet, M.R. De Long (Eds.).
-
(2004)
Dystonia 4: Advances in Neurology
, pp. 79-85
-
-
Caldwell, G.A.1
Cao, S.2
Gelwix, C.C.3
Sexton, E.G.4
Caldwell, K.A.5
-
20
-
-
3242700773
-
+-ATPase 23 Gene ATP1A3 are Associated with Rapid-Onset Dystonia Parkinsonism
-
+-ATPase 23 Gene ATP1A3 are Associated with Rapid-Onset Dystonia Parkinsonism. Neuron 2004, 43:169-175.
-
(2004)
Neuron
, vol.43
, pp. 169-175
-
-
De Carvalho Aguiar, P.1
Sweadhner, K.J.2
Penniston, J.T.3
Zaremba, J.4
Liu, L.5
Caton, M.6
Linazasoro, G.7
-
21
-
-
0037726598
-
Interaction of Aktphosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1
-
Chen H.K., Femandez-Funez P., Acevedo S.F., Lam Y.V., Kaytor M.D., Femandez-Funez M.H., Acevedo S.F., Lam Y.V., Kaytor M.D., Femandez M.H., Aitken A., et al. Interaction of Aktphosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1. Cell 2003, 113:457-468.
-
(2003)
Cell
, vol.113
, pp. 457-468
-
-
Chen, H.K.1
Femandez-Funez, P.2
Acevedo, S.F.3
Lam, Y.V.4
Kaytor, M.D.5
Femandez-Funez, M.H.6
Acevedo, S.F.7
Lam, Y.V.8
Kaytor, M.D.9
Femandez, M.H.10
Aitken, A.11
-
22
-
-
23444431611
-
Green fluorescent protein as a marker for gene expression
-
Chalfie M., Tu Y., Euskirchen G., Ward W.W., Prasher D.C. Green fluorescent protein as a marker for gene expression. Science 1994, 263:802-805.
-
(1994)
Science
, vol.263
, pp. 802-805
-
-
Chalfie, M.1
Tu, Y.2
Euskirchen, G.3
Ward, W.W.4
Prasher, D.C.5
-
23
-
-
0037075202
-
A primary culture system for functional analysis of C. elegans neurons and muscle cells
-
Christensen M., Estevez A., Yin X., Fox R., Morrison R., McDonnell M., Gleason C., et al. A primary culture system for functional analysis of C. elegans neurons and muscle cells. Neuron 2002, 33:503-514.
-
(2002)
Neuron
, vol.33
, pp. 503-514
-
-
Christensen, M.1
Estevez, A.2
Yin, X.3
Fox, R.4
Morrison, R.5
McDonnell, M.6
Gleason, C.7
-
24
-
-
0141987860
-
The ubiquitin proteosome system in neurodegenerative disease: sometimes the chicken, sometimes the egg
-
Ciechanover A., Brundin P. The ubiquitin proteosome system in neurodegenerative disease: sometimes the chicken, sometimes the egg. Neuron 2003, 40:427-446.
-
(2003)
Neuron
, vol.40
, pp. 427-446
-
-
Ciechanover, A.1
Brundin, P.2
-
25
-
-
0037426917
-
Pathways to Parkinsonism
-
Cookson M. Pathways to Parkinsonism. Neuron 2003, 37:7-10.
-
(2003)
Neuron
, vol.37
, pp. 7-10
-
-
Cookson, M.1
-
26
-
-
0034008852
-
Enhanced vulnerability to oxidative stress by alpha-synuclein mutations and C-terminal truncation
-
Danda S., Bishop J.F., Eglitis M.A., Yang Y., Mouradian M.M. Enhanced vulnerability to oxidative stress by alpha-synuclein mutations and C-terminal truncation. Neuroscience 2000, 97:279-284.
-
(2000)
Neuroscience
, vol.97
, pp. 279-284
-
-
Danda, S.1
Bishop, J.F.2
Eglitis, M.A.3
Yang, Y.4
Mouradian, M.M.5
-
27
-
-
18544410106
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
-
Davies S.W., Turmaine M., Cozens B.A., Difglia M., Sharp A.H., Ross C.A., Scherzinger E., et al. Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation. Cell 1997, 90:537-548.
-
(1997)
Cell
, vol.90
, pp. 537-548
-
-
Davies, S.W.1
Turmaine, M.2
Cozens, B.A.3
Difglia, M.4
Sharp, A.H.5
Ross, C.A.6
Scherzinger, E.7
-
28
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
DiFiglia M., Sapp E., Chase K.O., Davies S.W., Bates G.P., Vonsattel J.P., Aronin N. Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science 1997, 277:1990-1993.
-
(1997)
Science
, vol.277
, pp. 1990-1993
-
-
DiFiglia, M.1
Sapp, E.2
Chase, K.O.3
Davies, S.W.4
Bates, G.P.5
Vonsattel, J.P.6
Aronin, N.7
-
29
-
-
0026164539
-
Mitochondrial DNA and Parkinson's disease
-
Di Monte D.A. Mitochondrial DNA and Parkinson's disease. Neurology 1991, 41:38-42.
-
(1991)
Neurology
, vol.41
, pp. 38-42
-
-
Di Monte, D.A.1
-
30
-
-
12244281810
-
Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid beta-peptide (1-42) in a transgenic Caenorhaditis elegans model
-
Drake J., Link C.D., Butterfield D. Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid beta-peptide (1-42) in a transgenic Caenorhaditis elegans model. Neurobiol Aging 2003, 24:415-420.
-
(2003)
Neurobiol Aging
, vol.24
, pp. 415-420
-
-
Drake, J.1
Link, C.D.2
Butterfield, D.3
-
31
-
-
0037373633
-
Dying for a cause: invertebrate genetics takes on human neurodegeneration
-
Driscoll M., Grestbrein B. Dying for a cause: invertebrate genetics takes on human neurodegeneration. Nat Rev Genet 2003, 4:181-194.
-
(2003)
Nat Rev Genet
, vol.4
, pp. 181-194
-
-
Driscoll, M.1
Grestbrein, B.2
-
32
-
-
0035807904
-
Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease
-
Du Y., Ma Z., Lin S., Dodel R.C., Gao F., Bales K.P., Triarhou L.C., et al. Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease. Proc Natl Acad Sci USA 2001, 98:14669-14674.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 14669-14674
-
-
Du, Y.1
Ma, Z.2
Lin, S.3
Dodel, R.C.4
Gao, F.5
Bales, K.P.6
Triarhou, L.C.7
-
33
-
-
0032958758
-
The cat-1 gene of Caenorhabditis elegans encodes a vesicular monoamine transporter required for specific monoamine-dependent behaviors
-
Duerr J.S., Frisby D.L., Gaskin J., Duke A., Asermely K., Huddleston D., Eiden L.E., Rand J.B. The cat-1 gene of Caenorhabditis elegans encodes a vesicular monoamine transporter required for specific monoamine-dependent behaviors. J Neurosci 1999, 19:72-84.
-
(1999)
J Neurosci
, vol.19
, pp. 72-84
-
-
Duerr, J.S.1
Frisby, D.L.2
Gaskin, J.3
Duke, A.4
Asermely, K.5
Huddleston, D.6
Eiden, L.E.7
Rand, J.B.8
-
34
-
-
0027240431
-
Trinucleotide repeat length instability and age of onset in Huntington's disease
-
Duyao M., Ambrose C., Myers R., Novelletto A., Persichetti F., Frontali M., Folstein S., et al. Trinucleotide repeat length instability and age of onset in Huntington's disease. Nat Genet 1993, 4:387-392.
-
(1993)
Nat Genet
, vol.4
, pp. 387-392
-
-
Duyao, M.1
Ambrose, C.2
Myers, R.3
Novelletto, A.4
Persichetti, F.5
Frontali, M.6
Folstein, S.7
-
35
-
-
0037846441
-
Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice
-
Emamian E.S., Kaytor M.D., Duvick L.A., Zu T., Tousey S.K., Zoghbi H.Y., Clark H.B., Orr H.T. Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice. Neuron 2003, 38:375-387.
-
(2003)
Neuron
, vol.38
, pp. 375-387
-
-
Emamian, E.S.1
Kaytor, M.D.2
Duvick, L.A.3
Zu, T.4
Tousey, S.K.5
Zoghbi, H.Y.6
Clark, H.B.7
Orr, H.T.8
-
36
-
-
0029042393
-
Biochemical, physiological and medical aspects of ubiquinone function
-
Ernster E.D. Biochemical, physiological and medical aspects of ubiquinone function. Biochim Biophys Acta 1995, 1271:195-204.
-
(1995)
Biochim Biophys Acta
, vol.1271
, pp. 195-204
-
-
Ernster, E.D.1
-
37
-
-
0031662269
-
Huntingtin interacts with a family of WW domain proteins
-
Faber P.W., Barnes G.T., Srinidhi J., Chen J., Gusella J.F., MacDonald M.E. Huntingtin interacts with a family of WW domain proteins. Hum Mol Genet 1998, 7:1463-1474.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 1463-1474
-
-
Faber, P.W.1
Barnes, G.T.2
Srinidhi, J.3
Chen, J.4
Gusella, J.F.5
MacDonald, M.E.6
-
38
-
-
0033524413
-
Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron
-
Faber P.W., Alter J.R., Macdonald M.E., Hart A.C. Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron. Proc Natl Acad Sci USA 1999, 96:179-184.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 179-184
-
-
Faber, P.W.1
Alter, J.R.2
Macdonald, M.E.3
Hart, A.C.4
-
39
-
-
0037168585
-
Glutamine/proline-rich PQE-1 proteins protect Caenorhabditis elegans neurons from huntingtin polyglutamine neurotoxicity
-
Faber P.W., Voisine C., King D.C., Bates E.A., Hart A.C. Glutamine/proline-rich PQE-1 proteins protect Caenorhabditis elegans neurons from huntingtin polyglutamine neurotoxicity. Proc Natl Acad Sci USA 2002, 99:17131-17136.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 17131-17136
-
-
Faber, P.W.1
Voisine, C.2
King, D.C.3
Bates, E.A.4
Hart, A.C.5
-
40
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
Feany M.B., Bender W.W. A Drosophila model of Parkinson's disease. Nature 2000, 404:394-398.
-
(2000)
Nature
, vol.404
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
41
-
-
0141483742
-
Transport of dsRNA into cells by the transmembrane protein SID-1
-
Feinberg E.H., Hunter C.P. Transport of dsRNA into cells by the transmembrane protein SID-1. Science 2003, 301:1545-1547.
-
(2003)
Science
, vol.301
, pp. 1545-1547
-
-
Feinberg, E.H.1
Hunter, C.P.2
-
42
-
-
0033118981
-
CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans
-
Felkai S., Ewbank J.J., Lemieux J., Labbe J.C., Brown G.G., Hekimi S. CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans. EMBO J 1999, 18:1783-1792.
-
(1999)
EMBO J
, vol.18
, pp. 1783-1792
-
-
Felkai, S.1
Ewbank, J.J.2
Lemieux, J.3
Labbe, J.C.4
Brown, G.G.5
Hekimi, S.6
-
43
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A., Xu S., Montgomery M.K., Kostas S.A., Driver S.E., Mello C.C. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998, 391:806-881.
-
(1998)
Nature
, vol.391
, pp. 806-881
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
44
-
-
0024021560
-
AcylCoA dehydrogenase, electron transport flavoproteins and electron transport flavoprotein dehydrogenase
-
Frerman F.E. AcylCoA dehydrogenase, electron transport flavoproteins and electron transport flavoprotein dehydrogenase. Biochem Soc Trans 1988, 16:416-418.
-
(1988)
Biochem Soc Trans
, vol.16
, pp. 416-418
-
-
Frerman, F.E.1
-
45
-
-
0031727163
-
Genetics of Parkinson's disease
-
Gasser T. Genetics of Parkinson's disease. Clin Genet 1998, 54:259-265.
-
(1998)
Clin Genet
, vol.54
, pp. 259-265
-
-
Gasser, T.1
-
47
-
-
0035409575
-
Alpha-synuclein and neurodegenerative diseases
-
Goedert M. Alpha-synuclein and neurodegenerative diseases. Nat Rev Neurosci 2001, 2:492-501.
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 492-501
-
-
Goedert, M.1
-
48
-
-
0343052915
-
Age-related changes in nociception, behavior and monoamine levels in rats
-
Goicoechea C., Ormazabal M., Alfaro M., Martin M. Age-related changes in nociception, behavior and monoamine levels in rats. Gen Pharm 1997, 28:116-331.
-
(1997)
Gen Pharm
, vol.28
, pp. 116-331
-
-
Goicoechea, C.1
Ormazabal, M.2
Alfaro, M.3
Martin, M.4
-
49
-
-
0034043595
-
Neuroprotective strategies in Parkinson's disease using the models of 6-OHDA and MPTP
-
Grunblatt E., Mandel S., Youdim M.B. Neuroprotective strategies in Parkinson's disease using the models of 6-OHDA and MPTP. Ann NY Acad Sci 2000, 899:262-273.
-
(2000)
Ann NY Acad Sci
, vol.899
, pp. 262-273
-
-
Grunblatt, E.1
Mandel, S.2
Youdim, M.B.3
-
50
-
-
0026754574
-
Reactive oxygen species and the central nervous system
-
Halliwell B. Reactive oxygen species and the central nervous system. J Neurochem 1992, 59:1609-1623.
-
(1992)
J Neurochem
, vol.59
, pp. 1609-1623
-
-
Halliwell, B.1
-
51
-
-
0037246685
-
WormBase: a cross-species database for comparative genomics
-
Harris T.W., Lee R., Schwarz E., Bradnam K., Lawson D., Chen W., Blasier D., et al. WormBase: a cross-species database for comparative genomics. Nucleic Acids Res 2003, 31:133-137.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 133-137
-
-
Harris, T.W.1
Lee, R.2
Schwarz, E.3
Bradnam, K.4
Lawson, D.5
Chen, W.6
Blasier, D.7
-
52
-
-
0037167855
-
Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans
-
Herndon L.A., Schmeissner P.J., Dudaronek J.M., Brown P.A., Listner K.M., Sakano Y., Paupard M.C., et al. Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans. Nature 2002, 419:808-814.
-
(2002)
Nature
, vol.419
, pp. 808-814
-
-
Herndon, L.A.1
Schmeissner, P.J.2
Dudaronek, J.M.3
Brown, P.A.4
Listner, K.M.5
Sakano, Y.6
Paupard, M.C.7
-
53
-
-
0034702033
-
Mutant torsin A, responsible for early-onset torsion dystonia, forms membrane inclusions in cultured neural cells
-
Hewett J., Gonzalez-Agosti C., Slater D., Ziefer P., Li S., Bergeron D., Jacoby D.J., et al. Mutant torsin A, responsible for early-onset torsion dystonia, forms membrane inclusions in cultured neural cells. Hum Mol Gen 2000, 9:1203-1313.
-
(2000)
Hum Mol Gen
, vol.9
, pp. 1203-1313
-
-
Hewett, J.1
Gonzalez-Agosti, C.2
Slater, D.3
Ziefer, P.4
Li, S.5
Bergeron, D.6
Jacoby, D.J.7
-
54
-
-
0344838402
-
Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease
-
Holbert S., Dedeoglu A., Humbert S., Saudou F., Ferrante R.J., Neri C. Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease. Proc Natl Acad Sci USA 2003, 100:2712-2717.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 2712-2717
-
-
Holbert, S.1
Dedeoglu, A.2
Humbert, S.3
Saudou, F.4
Ferrante, R.J.5
Neri, C.6
-
55
-
-
0033890821
-
Alpha-synuclein promotes mitochondrial deficit and oxidative stress
-
Hsu L.J., Sagara Y., Arroyo A., Rockenstein E., Sisk A., Mallory M., Wong J., et al. Alpha-synuclein promotes mitochondrial deficit and oxidative stress. Am J Pathol 2000, 157:401-410.
-
(2000)
Am J Pathol
, vol.157
, pp. 401-410
-
-
Hsu, L.J.1
Sagara, Y.2
Arroyo, A.3
Rockenstein, E.4
Sisk, A.5
Mallory, M.6
Wong, J.7
-
56
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
Huntington's Disease Collaborative Research Group
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993, 72:971-983. Huntington's Disease Collaborative Research Group.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
57
-
-
0028151448
-
Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene
-
Ichinose H., Ohye T., Takahashi E., Seki N., Hori T., Segawa M., Nomura Y., et al. Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene. Nat Genet 1994, 8:236-242.
-
(1994)
Nat Genet
, vol.8
, pp. 236-242
-
-
Ichinose, H.1
Ohye, T.2
Takahashi, E.3
Seki, N.4
Hori, T.5
Segawa, M.6
Nomura, Y.7
-
58
-
-
0000340348
-
Parkinsonism-inducing neurotoxin, N-MPTP: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity
-
Javitch J., D'Amato R.J., Strittmatter S.M., Snyder S.H. Parkinsonism-inducing neurotoxin, N-MPTP: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity. Proc Natl Acad Sci USA 1985, 82:2173-2177.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 2173-2177
-
-
Javitch, J.1
D'Amato, R.J.2
Strittmatter, S.M.3
Snyder, S.H.4
-
59
-
-
0031754719
-
The C. elegans gene T23G5.5 encodes an antidepressant and cocaine sensitive dopamine transporter
-
Jayanthi L.D., Apparsundaram S., Malone D., Ward E., Miller D.M., Eppler M., Blakely R.D. The C. elegans gene T23G5.5 encodes an antidepressant and cocaine sensitive dopamine transporter. Mol Pharmacol 1998, 545:601-609.
-
(1998)
Mol Pharmacol
, vol.545
, pp. 601-609
-
-
Jayanthi, L.D.1
Apparsundaram, S.2
Malone, D.3
Ward, E.4
Miller, D.M.5
Eppler, M.6
Blakely, R.D.7
-
60
-
-
0035895199
-
A dietary source of coenzyme Q is essential for growth of longlived C. elegans clk-1 mutants
-
Jonassen T., Larsen P.L., Clarke C.F. A dietary source of coenzyme Q is essential for growth of longlived C. elegans clk-1 mutants. Proc Natl Acad Sci USA 2001, 2:421-426.
-
(2001)
Proc Natl Acad Sci USA
, vol.2
, pp. 421-426
-
-
Jonassen, T.1
Larsen, P.L.2
Clarke, C.F.3
-
61
-
-
0036254584
-
The art and design of genetic screens: Caenorhabditis elegans
-
Jorgensen E.M., Mango S.E. The art and design of genetic screens: Caenorhabditis elegans. Nat Rev Genet 2002, 3:356-369.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 356-369
-
-
Jorgensen, E.M.1
Mango, S.E.2
-
62
-
-
0035229245
-
Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans
-
Kamath R.S., Martinez-Campos M., Zipperlen P., Fraser A.G., Ahringer J. Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans. Genome Biol 2001, 2:1-10.
-
(2001)
Genome Biol
, vol.2
, pp. 1-10
-
-
Kamath, R.S.1
Martinez-Campos, M.2
Zipperlen, P.3
Fraser, A.G.4
Ahringer, J.5
-
63
-
-
0037448540
-
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
-
Kamath R.S., Fraser A.G., Dong Y., Durbin Y., Poulin G., Durbin R., Cotta M., et al. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 2003, 421:231-237.
-
(2003)
Nature
, vol.421
, pp. 231-237
-
-
Kamath, R.S.1
Fraser, A.G.2
Dong, Y.3
Durbin, Y.4
Poulin, G.5
Durbin, R.6
Cotta, M.7
-
64
-
-
0033680858
-
Optical imaging of calcium transients in neurons and pharyngeal muscle of C. elegans
-
Kerr R., Lev-Ram V., Baird G., Incent P., Tsien R.Y., Schafer W.R. Optical imaging of calcium transients in neurons and pharyngeal muscle of C. elegans. Neuron 2000, 26:583-594.
-
(2000)
Neuron
, vol.26
, pp. 583-594
-
-
Kerr, R.1
Lev-Ram, V.2
Baird, G.3
Incent, P.4
Tsien, R.Y.5
Schafer, W.R.6
-
65
-
-
0034457113
-
The ortholog of human ataxin-2 is essential for early embryonic patterning in C. elegans
-
Kiehl T.R., Shibata H., Pulst S.M. The ortholog of human ataxin-2 is essential for early embryonic patterning in C. elegans. J Mol Neurosci 2000, 15:231-241.
-
(2000)
J Mol Neurosci
, vol.15
, pp. 231-241
-
-
Kiehl, T.R.1
Shibata, H.2
Pulst, S.M.3
-
66
-
-
0035860551
-
A gene expression map for Caenorhabditis elegans
-
Kim S.K., Lund J., Kiraly M., Duke K., Jiang M., Stuart J.M., Eizinger A., et al. A gene expression map for Caenorhabditis elegans. Science 2001, 293:2087-2092.
-
(2001)
Science
, vol.293
, pp. 2087-2092
-
-
Kim, S.K.1
Lund, J.2
Kiraly, M.3
Duke, K.4
Jiang, M.5
Stuart, J.M.6
Eizinger, A.7
-
67
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T., Asakawa S., Hattori N., Matsumine H., Yamamura Y., Minoshima S., Yokochi M., et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998, 392:605-608.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
-
68
-
-
0026671035
-
Parkinsonism-inducing neurotoxin MPP+; uptake and toxicity in nonneuronal COS cells expressing dopamine transporter cDNA
-
Kitayama S., Shimada S., Uhl G.R. Parkinsonism-inducing neurotoxin MPP+; uptake and toxicity in nonneuronal COS cells expressing dopamine transporter cDNA. Ann Neurol 1992, 32:109-111.
-
(1992)
Ann Neurol
, vol.32
, pp. 109-111
-
-
Kitayama, S.1
Shimada, S.2
Uhl, G.R.3
-
69
-
-
0034578389
-
Aggresomes, inclusion bodies and protein aggregation
-
Kopito R.R. Aggresomes, inclusion bodies and protein aggregation. Trends Cell Biol 2000, 10:524-530.
-
(2000)
Trends Cell Biol
, vol.10
, pp. 524-530
-
-
Kopito, R.R.1
-
70
-
-
0031990490
-
Ala30Pro mutation in the gene encoding ?-synuclein gene identified in families with Parkinson's disease
-
Kruger R., Kuhn W., Muller T., Woitalla D., Graeber M., Kosel S., Przuntek H., et al. Ala30Pro mutation in the gene encoding ?-synuclein gene identified in families with Parkinson's disease. Nat Genet 1998, 28:106-108.
-
(1998)
Nat Genet
, vol.28
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
Przuntek, H.7
-
71
-
-
0034623158
-
TorsinA and its torsion dystonia-associated mutant forms are lumenal glycoproteins that exhibit distinct subcellular localizations
-
Kustedjo K., Bracey M.H., Cravatt B.F. TorsinA and its torsion dystonia-associated mutant forms are lumenal glycoproteins that exhibit distinct subcellular localizations. J Biol Chem 2000, 275:27933-27939.
-
(2000)
J Biol Chem
, vol.275
, pp. 27933-27939
-
-
Kustedjo, K.1
Bracey, M.H.2
Cravatt, B.F.3
-
72
-
-
0037971209
-
Dopaminergic neuronal loss and motor deficits in C. elegans overexpressing human ?-synuclein
-
Lakso M., Vartiainen S., Moilanen A., Sirvio J., Thomas J.H., Nass R., Blakely R.D., Wong G. Dopaminergic neuronal loss and motor deficits in C. elegans overexpressing human ?-synuclein. J Neurochem 2003, 86:165-172.
-
(2003)
J Neurochem
, vol.86
, pp. 165-172
-
-
Lakso, M.1
Vartiainen, S.2
Moilanen, A.3
Sirvio, J.4
Thomas, J.H.5
Nass, R.6
Blakely, R.D.7
Wong, G.8
-
73
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander E.S., Linton L.M., Birren B., Nusbaum C., Zody M.C., Baldwin J., Devon K., et al. Initial sequencing and analysis of the human genome. Nature 2001, 409:860-921.
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
Nusbaum, C.4
Zody, M.C.5
Baldwin, J.6
Devon, K.7
-
74
-
-
0032497504
-
Parkinson's disease. First of two parts
-
Lang A.E., Lozano A.M. Parkinson's disease. First of two parts. N Engl J Med 1998, 339:1044-1053.
-
(1998)
N Engl J Med
, vol.339
, pp. 1044-1053
-
-
Lang, A.E.1
Lozano, A.M.2
-
75
-
-
0037016442
-
Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q
-
Larsen P.L., Clarke C.F. Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q. Science 2002, 295:120-123.
-
(2002)
Science
, vol.295
, pp. 120-123
-
-
Larsen, P.L.1
Clarke, C.F.2
-
76
-
-
0037228016
-
A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
-
Lee S.S., Lee R.Y.N., Fraser A.G., Kamath R.S., Ahringer J., Ruvkun G. A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Nat Gene 2002, 33:40-48.
-
(2002)
Nat Gene
, vol.33
, pp. 40-48
-
-
Lee, S.S.1
Lee, R.Y.N.2
Fraser, A.G.3
Kamath, R.S.4
Ahringer, J.5
Ruvkun, G.6
-
77
-
-
18044403431
-
Novel mutation in the TOR1A (DYT1) gene in atypical early onset dystonia and polymorphisms in dystonia and early onset parkinsonism
-
Leung J.C., Klein C., Friedman J., Vieregge P., Jacobs H., Doheny D., Kamm C., et al. Novel mutation in the TOR1A (DYT1) gene in atypical early onset dystonia and polymorphisms in dystonia and early onset parkinsonism. Neurogenetics 2001, 3:133-143.
-
(2001)
Neurogenetics
, vol.3
, pp. 133-143
-
-
Leung, J.C.1
Klein, C.2
Friedman, J.3
Vieregge, P.4
Jacobs, H.5
Doheny, D.6
Kamm, C.7
-
78
-
-
0035975702
-
Transgenic invertebrate models of age-associated neurodegenerative diseases
-
Link C.D. Transgenic invertebrate models of age-associated neurodegenerative diseases. Mech Ageing Dev 2001, 122:1639-1649.
-
(2001)
Mech Ageing Dev
, vol.122
, pp. 1639-1649
-
-
Link, C.D.1
-
79
-
-
0036175825
-
Stress resistance as a determinant of C. elegans lifespan
-
Lithgow G.J., Walker G.A. Stress resistance as a determinant of C. elegans lifespan. Mech Ageing Dev 2002, 123:765-771.
-
(2002)
Mech Ageing Dev
, vol.123
, pp. 765-771
-
-
Lithgow, G.J.1
Walker, G.A.2
-
80
-
-
0033374598
-
Patterning of dopaminergic neurotransmitter identity among C. elegans ray sensory neurons by a TGFB family signaling pathway and a Hox gene
-
Lints R., Emmons S.W. Patterning of dopaminergic neurotransmitter identity among C. elegans ray sensory neurons by a TGFB family signaling pathway and a Hox gene. Development 1999, 126:5819-5831.
-
(1999)
Development
, vol.126
, pp. 5819-5831
-
-
Lints, R.1
Emmons, S.W.2
-
81
-
-
0027131206
-
Serotonin-deficient mutants and male mating behavior in the nematode C. elegans
-
Loer C.M., Kenyon C.J. Serotonin-deficient mutants and male mating behavior in the nematode C. elegans. J Neurosci 1993, 13:5407-5417.
-
(1993)
J Neurosci
, vol.13
, pp. 5407-5417
-
-
Loer, C.M.1
Kenyon, C.J.2
-
82
-
-
0034285017
-
CREB-binding protein sequestration by expanded polyglutamine
-
McCampbell A., Taylor J.P., Taye A.A., Robitschek J., Li M., Walcott J., Merry D., et al. CREB-binding protein sequestration by expanded polyglutamine. Hum Mol Genet 2000, 9:2197-2202.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 2197-2202
-
-
McCampbell, A.1
Taylor, J.P.2
Taye, A.A.3
Robitschek, J.4
Li, M.5
Walcott, J.6
Merry, D.7
-
83
-
-
0036846119
-
TorsinA and heat shock proteins act a molecular chaperones: suppression of ?-synuclein aggregation
-
McLean P.J., Kawamata H., Saadat S., Hewett J., Sharma N., Ueda K., Breakefield X.O., Hyman B.T. TorsinA and heat shock proteins act a molecular chaperones: suppression of ?-synuclein aggregation. J Neurochem 2002, 83:846-854.
-
(2002)
J Neurochem
, vol.83
, pp. 846-854
-
-
McLean, P.J.1
Kawamata, H.2
Saadat, S.3
Hewett, J.4
Sharma, N.5
Ueda, K.6
Breakefield, X.O.7
Hyman, B.T.8
-
84
-
-
0141891215
-
Pathogenesis of polyglutamine disorders: aggregation revisited
-
Michalik A., Van Broeckhoven C. Pathogenesis of polyglutamine disorders: aggregation revisited. Hum Mol Genet 2003, 12:R173-R186.
-
(2003)
Hum Mol Genet
, vol.12
-
-
Michalik, A.1
Van Broeckhoven, C.2
-
85
-
-
0032914618
-
A two-color GFP expression system for C. elegans
-
Miller D.M., Desai N., Hardin D., Piston D.W., Patterson G.H., Fleenor J., Xu S.Q., Fire A. A two-color GFP expression system for C. elegans. BioTechniques 1999, 26:914-921.
-
(1999)
BioTechniques
, vol.26
, pp. 914-921
-
-
Miller, D.M.1
Desai, N.2
Hardin, D.3
Piston, D.W.4
Patterson, G.H.5
Fleenor, J.6
Xu, S.Q.7
Fire, A.8
-
86
-
-
0036678146
-
The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans
-
Morley J.F., Brignull H.R., Weyers J.J., Morimoto R.I. The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans. Proc Natl Acad Sci USA 2002, 99:10417-10422.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10417-10422
-
-
Morley, J.F.1
Brignull, H.R.2
Weyers, J.J.3
Morimoto, R.I.4
-
87
-
-
0036100124
-
Evidence suggesting that a fifth of annotated Caenorhabditis elegans genes may be pseudogenes
-
Mounsey A., Bauer P., Hope I.A. Evidence suggesting that a fifth of annotated Caenorhabditis elegans genes may be pseudogenes. Genome Res 2002, 12:770-775.
-
(2002)
Genome Res
, vol.12
, pp. 770-775
-
-
Mounsey, A.1
Bauer, P.2
Hope, I.A.3
-
88
-
-
0042092531
-
-
Murphy C.T., McCarroll S.A., Bargmann C.I., Fraser A., Kamath R.S., Ahringer J., Li H., Kenyon C. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans 2003, 424:277-284.
-
(2003)
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
, vol.424
, pp. 277-284
-
-
Murphy, C.T.1
McCarroll, S.A.2
Bargmann, C.I.3
Fraser, A.4
Kamath, R.S.5
Ahringer, J.6
Li, H.7
Kenyon, C.8
-
89
-
-
0037022668
-
Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans
-
Nass R., Hall D.H., Miller D.M., Blakely R.D. Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans. Proc Natl Acad Sci USA 2002, 99:3264-3269.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 3264-3269
-
-
Nass, R.1
Hall, D.H.2
Miller, D.M.3
Blakely, R.D.4
-
90
-
-
0034594461
-
Dopamine and senescence in D. melanogaster
-
Neckamayer W., Woodrome S., Holt B., Mayer A. Dopamine and senescence in D. melanogaster. Neurobiol Aging 2000, 1:145-152.
-
(2000)
Neurobiol Aging
, vol.1
, pp. 145-152
-
-
Neckamayer, W.1
Woodrome, S.2
Holt, B.3
Mayer, A.4
-
91
-
-
0032969563
-
AAA+: a class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes
-
Neuwald A.F., Aravind L., Spouge J.L., Koonin E.V. AAA+: a class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res 1999, 9:27-43.
-
(1999)
Genome Res
, vol.9
, pp. 27-43
-
-
Neuwald, A.F.1
Aravind, L.2
Spouge, J.L.3
Koonin, E.V.4
-
92
-
-
0035937523
-
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity
-
Nucifora F.C.J., Sasaki M., Peters M.F., Huang H., Cooper J.K., Yamada M., Takahashi H., et al. Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity. Science 2001, 2423-2428.
-
(2001)
Science
, pp. 2423-2428
-
-
Nucifora, F.C.J.1
Sasaki, M.2
Peters, M.F.3
Huang, H.4
Cooper, J.K.5
Yamada, M.6
Takahashi, H.7
-
93
-
-
0034772838
-
Oxidative stress causes abnormal accumulation of familial amyotrophic lateral sclerosis-related mutant SOD1 in transgenic Caenorhabditis elegans
-
Oeda T., Shimohama S., Kitagawa N., Kohno R., Mura T., Shibasaki H., Ishii N. Oxidative stress causes abnormal accumulation of familial amyotrophic lateral sclerosis-related mutant SOD1 in transgenic Caenorhabditis elegans. Hum Mol Genet 2003, 19:2013=2023.
-
(2003)
Hum Mol Genet
, vol.19
-
-
Oeda, T.1
Shimohama, S.2
Kitagawa, N.3
Kohno, R.4
Mura, T.5
Shibasaki, H.6
Ishii, N.7
-
94
-
-
0031577584
-
Oligomerization of expanded-polyglutamine domain fluorescent fusion proteins in cultured mammalian cells
-
Onodera O., Burke J.R., Miller S.E., Hester S., Tsuji S., Roses A.D., Strittmatter W.J. Oligomerization of expanded-polyglutamine domain fluorescent fusion proteins in cultured mammalian cells. Biochem Biophys Res Comm 1997, 238:599-605.
-
(1997)
Biochem Biophys Res Comm
, vol.238
, pp. 599-605
-
-
Onodera, O.1
Burke, J.R.2
Miller, S.E.3
Hester, S.4
Tsuji, S.5
Roses, A.D.6
Strittmatter, W.J.7
-
95
-
-
16944366666
-
The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein
-
Ozelius L.J., Hewett J.W., Page C.E., Bressman S.B., Kramer P.L., Shalish C., de Leon D., et al. The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein. Nat Genet 1997, 17:40-48.
-
(1997)
Nat Genet
, vol.17
, pp. 40-48
-
-
Ozelius, L.J.1
Hewett, J.W.2
Page, C.E.3
Bressman, S.B.4
Kramer, P.L.5
Shalish, C.6
de Leon, D.7
-
96
-
-
0033572356
-
The TOR1A (DYT1) gene family and its role in early onset torsion dystonia
-
Ozelius L.J., Page C.E., Klein C., Hewett J.W., Mineta M., Leung J., Shalish C., et al. The TOR1A (DYT1) gene family and its role in early onset torsion dystonia. Genomics 1999, 62:377-384.
-
(1999)
Genomics
, vol.62
, pp. 377-384
-
-
Ozelius, L.J.1
Page, C.E.2
Klein, C.3
Hewett, J.W.4
Mineta, M.5
Leung, J.6
Shalish, C.7
-
97
-
-
0035818590
-
Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death
-
Parker J.A., Connolly J.B., Wellington C., Hayden M., Dausset J., Neri C. Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death. Proc Natl Acad Sci USA 2001, 98:13318-13323.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13318-13323
-
-
Parker, J.A.1
Connolly, J.B.2
Wellington, C.3
Hayden, M.4
Dausset, J.5
Neri, C.6
-
98
-
-
0031864164
-
Extension of Drosophila life span by overexpression of human SOD1 in motorneurons
-
Parkes T.L., Elia A.J., Dickinson D., Hilliker A.J., Phillips J.P., Boulianne G.L. Extension of Drosophila life span by overexpression of human SOD1 in motorneurons. Nature Genetics 1998, 19:171-174.
-
(1998)
Nature Genetics
, vol.19
, pp. 171-174
-
-
Parkes, T.L.1
Elia, A.J.2
Dickinson, D.3
Hilliker, A.J.4
Phillips, J.P.5
Boulianne, G.L.6
-
99
-
-
0036680051
-
Oxidation of DNA, protein and lipids by DOPA protein-bound DOPA, and related catecholamines
-
Pattison D.I., Dean R.T., Davies M.J. Oxidation of DNA, protein and lipids by DOPA protein-bound DOPA, and related catecholamines. Toxicology 2001, 177:23-37.
-
(2001)
Toxicology
, vol.177
, pp. 23-37
-
-
Pattison, D.I.1
Dean, R.T.2
Davies, M.J.3
-
100
-
-
0030850412
-
Intranuclear inclusions of expanded polyglutamine protein in spino cerebellar ataxia type 3
-
Paulson H.L., Perez M.K., Trottier Y., Trojanowski J.Q., Subramony S.H., Das S.S., P.Vig, et al. Intranuclear inclusions of expanded polyglutamine protein in spino cerebellar ataxia type 3. Neuron 1997, 19:333-344.
-
(1997)
Neuron
, vol.19
, pp. 333-344
-
-
Paulson, H.L.1
Perez, M.K.2
Trottier, Y.3
Trojanowski, J.Q.4
Subramony, S.H.5
Das, S.S.6
Vig, P.7
-
101
-
-
0032847708
-
Nuclear targeting of mutant Huntingtin increases toxicity
-
Peters M.F., Nucifora F.C., Kushi J., Seaman H.C., Cooper J.K., Herring W.J., Dawson V.L., et al. Nuclear targeting of mutant Huntingtin increases toxicity. Mol Cell Neurosci 1999, 14:121-128.
-
(1999)
Mol Cell Neurosci
, vol.14
, pp. 121-128
-
-
Peters, M.F.1
Nucifora, F.C.2
Kushi, J.3
Seaman, H.C.4
Cooper, J.K.5
Herring, W.J.6
Dawson, V.L.7
-
102
-
-
0027454020
-
Dopamine transporter expression confers cytotoxicity to low doses of the parkinsonism-inducing neurotoxin 1-MPP
-
Pifl C., Giros B., Caron M.G. Dopamine transporter expression confers cytotoxicity to low doses of the parkinsonism-inducing neurotoxin 1-MPP. J Neurosci 1993, 13:4246-4253.
-
(1993)
J Neurosci
, vol.13
, pp. 4246-4253
-
-
Pifl, C.1
Giros, B.2
Caron, M.G.3
-
103
-
-
0030744876
-
Mutation in the ?-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos M.H., Lavedan C., Leroy E., Ide S.E., Dehejia A., Dutra A., Pike B., et al. Mutation in the ?-synuclein gene identified in families with Parkinson's disease. Science 1997, 276:2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
-
104
-
-
0029089172
-
When more is less: pathogenesis of glutamine repeat neurodegenerative diseases
-
Ross C.A. When more is less: pathogenesis of glutamine repeat neurodegenerative diseases. Neuron 1995, 15:493-496.
-
(1995)
Neuron
, vol.15
, pp. 493-496
-
-
Ross, C.A.1
-
105
-
-
0034705224
-
Polyglutamine aggregates alter protein-folding homeostasis in Caenorhabditis elegans
-
Satyal S.H., Schmidt E., Kitagawa K., Sondheimer N., Lindquist S., Kramer J.M., Morimoto R.I. Polyglutamine aggregates alter protein-folding homeostasis in Caenorhabditis elegans. Proc Natl Acad Sci U S A 2000, 97:5750-5755.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 5750-5755
-
-
Satyal, S.H.1
Schmidt, E.2
Kitagawa, K.3
Sondheimer, N.4
Lindquist, S.5
Kramer, J.M.6
Morimoto, R.I.7
-
106
-
-
0032475931
-
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions
-
Saudou F., Finkbeiner S., Devys D., Greenberg M.E. Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell 1998, 95:55-66.
-
(1998)
Cell
, vol.95
, pp. 55-66
-
-
Saudou, F.1
Finkbeiner, S.2
Devys, D.3
Greenberg, M.E.4
-
107
-
-
0033714116
-
C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway
-
Sawin E.R., Ranganathan R., Horvitz H.R. C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway. Neuron 2000, 26:619-631.
-
(2000)
Neuron
, vol.26
, pp. 619-631
-
-
Sawin, E.R.1
Ranganathan, R.2
Horvitz, H.R.3
-
108
-
-
0141841634
-
Gene expression changes presage neurodegeneration in a Drosophila model of PD
-
Scherzer C.R., Jensen R.V., Gullans S.R., Feany M.B. Gene expression changes presage neurodegeneration in a Drosophila model of PD. Hum Mol Genet 2003, 12:2457-2466.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 2457-2466
-
-
Scherzer, C.R.1
Jensen, R.V.2
Gullans, S.R.3
Feany, M.B.4
-
109
-
-
0035404388
-
A close association of torsinA and alpha-synuclein in Lewy bodies: a fluorescence resonance energy transfer study
-
Sharma N., Hewett J., Ozelius L.J., Ramesh V., McLean P.J., Breakefield X.O., Hyman B.T. A close association of torsinA and alpha-synuclein in Lewy bodies: a fluorescence resonance energy transfer study. Am J Pathol 2001, 159:339-344.
-
(2001)
Am J Pathol
, vol.159
, pp. 339-344
-
-
Sharma, N.1
Hewett, J.2
Ozelius, L.J.3
Ramesh, V.4
McLean, P.J.5
Breakefield, X.O.6
Hyman, B.T.7
-
110
-
-
0034703336
-
TorsinA accumulation in Lewy bodies in sporadic Parkinson's disease
-
Shashidharan P., Good P.F., Hsu A., Perl D.P., Brin M.F., Olanow C.W. TorsinA accumulation in Lewy bodies in sporadic Parkinson's disease. Brain Res 2000, 877:379-381.
-
(2000)
Brain Res
, vol.877
, pp. 379-381
-
-
Shashidharan, P.1
Good, P.F.2
Hsu, A.3
Perl, D.P.4
Brin, M.F.5
Olanow, C.W.6
-
111
-
-
0033987354
-
Immunohistochemical localization and distribution of torsin A in normal human and rat brain
-
Shashidharan P., Kramer B.C., Walker R.H., Olanow C.W., Brin M.F. Immunohistochemical localization and distribution of torsin A in normal human and rat brain. Brain Res 2000, 853:197-206.
-
(2000)
Brain Res
, vol.853
, pp. 197-206
-
-
Shashidharan, P.1
Kramer, B.C.2
Walker, R.H.3
Olanow, C.W.4
Brin, M.F.5
-
112
-
-
0037031152
-
Loss of the putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi
-
Simmer F., Tijsterman M., Parrish S., Koushika S.P., Nonet M.L., Fire A., Ahringer J., Plasterk R.H. Loss of the putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi. Curr Biol 2002, 12(15):1317-1319.
-
(2002)
Curr Biol
, vol.12
, Issue.15
, pp. 1317-1319
-
-
Simmer, F.1
Tijsterman, M.2
Parrish, S.3
Koushika, S.P.4
Nonet, M.L.5
Fire, A.6
Ahringer, J.7
Plasterk, R.H.8
-
113
-
-
0242300619
-
Alpha-synuclei locus triplication causes Parkinson's disease
-
Singleton A.B., Farrer M., Johnson J., Singleton A., Hague S., Kachergus J., Hulihan M., et al. Alpha-synuclei locus triplication causes Parkinson's disease. Science 2003, 302:841.
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
-
114
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
Spillantini M.G., Schmidt M.L., Lee V.M., Trojanowski J.Q., Jakes R., Goedert M. Alpha-synuclein in Lewy bodies. Nature 1997, 388:839-840.
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
115
-
-
0026577362
-
The C. elegans genome sequencing project: A beginning
-
Sulston J., Du Z., Thomas K., Wilson R., Hillier L., Staden R., Halloran N., et al. The C. elegans genome sequencing project: A beginning. Nature 1992, 356:37-41.
-
(1992)
Nature
, vol.356
, pp. 37-41
-
-
Sulston, J.1
Du, Z.2
Thomas, K.3
Wilson, R.4
Hillier, L.5
Staden, R.6
Halloran, N.7
-
116
-
-
0032538391
-
RNAi in C. elegans: soaking in the genome sequence
-
Tabara H., Grishok A., Mello C.C. RNAi in C. elegans: soaking in the genome sequence. Science 1998, 282:430-431.
-
(1998)
Science
, vol.282
, pp. 430-431
-
-
Tabara, H.1
Grishok, A.2
Mello, C.C.3
-
117
-
-
0035870881
-
Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
-
Tanaka Y., Engelender S., Igarashi S., Rao R.K., Wanner T., Tanzi R.E., Sawa A.L., et al. Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis. Hum Mol Gen 2001, 10:919-926.
-
(2001)
Hum Mol Gen
, vol.10
, pp. 919-926
-
-
Tanaka, Y.1
Engelender, S.2
Igarashi, S.3
Rao, R.K.4
Wanner, T.5
Tanzi, R.E.6
Sawa, A.L.7
-
118
-
-
0036132431
-
Caloric restriction and lifespan: a role for protein turnover?
-
Tavernarakis N., Driscoll M. Caloric restriction and lifespan: a role for protein turnover?. Mech Aging Dev 2002, 123:215-229.
-
(2002)
Mech Aging Dev
, vol.123
, pp. 215-229
-
-
Tavernarakis, N.1
Driscoll, M.2
-
119
-
-
0033968037
-
Heritable and inducible genetic interference by double stranded RNA encoded by transgenes
-
Tavernarakis N., Wang S., Dorovokov M., Ryazanov A., Driscoll M. Heritable and inducible genetic interference by double stranded RNA encoded by transgenes. Nature Genetics 2000, 24:180-183.
-
(2000)
Nature Genetics
, vol.24
, pp. 180-183
-
-
Tavernarakis, N.1
Wang, S.2
Dorovokov, M.3
Ryazanov, A.4
Driscoll, M.5
-
120
-
-
0035941485
-
Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans
-
Timmons L., Court D.L., Fire A. Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene 2001, 263:103-112.
-
(2001)
Gene
, vol.263
, pp. 103-112
-
-
Timmons, L.1
Court, D.L.2
Fire, A.3
-
121
-
-
0019558007
-
New concepts on the role of ubiquinone in the mitochondrial respiratory chain
-
Trumpower B. New concepts on the role of ubiquinone in the mitochondrial respiratory chain. J Bioenerg Biomem 1981, 13:1-24.
-
(1981)
J Bioenerg Biomem
, vol.13
, pp. 1-24
-
-
Trumpower, B.1
-
122
-
-
0034632063
-
AAA proteins. Lords of the ring
-
Vale R.D. AAA proteins. Lords of the ring. J Cell Biol 2000, 150:F13-F19.
-
(2000)
J Cell Biol
, vol.150
-
-
Vale, R.D.1
-
123
-
-
2442668926
-
Hereditary Early-Onset Parkinsonism Disease caused by mutations in PINK1
-
Valente F.M., Abou-Sleiman P.M., Caputo V., Muquit M.M.K., Harvey K., Gispert S., Ali Z., et al. Hereditary Early-Onset Parkinsonism Disease caused by mutations in PINK1. Science 2004, 304:1158-1160.
-
(2004)
Science
, vol.304
, pp. 1158-1160
-
-
Valente, F.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muquit, M.M.K.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
-
124
-
-
0035895505
-
The sequence of the human genome
-
Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., et al. The sequence of the human genome. Science 2001, 291:1304-1351.
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
Sutton, G.G.6
Smith, H.O.7
-
125
-
-
0034614678
-
Protein interaction mapping in C. elegans using proteins involved in vulval development
-
Walhout A.J., Sordella R., Lu X., Hartley J.L., Temple G.F., Brasch M.A., Thierry-Mieg N., Vidal M. Protein interaction mapping in C. elegans using proteins involved in vulval development. Science 2000, 287:116-122.
-
(2000)
Science
, vol.287
, pp. 116-122
-
-
Walhout, A.J.1
Sordella, R.2
Lu, X.3
Hartley, J.L.4
Temple, G.F.5
Brasch, M.A.6
Thierry-Mieg, N.7
Vidal, M.8
-
126
-
-
0141836952
-
TorsinA immunore-activity in inclusion bodies in trinucleotide repeat diseases
-
Walker R.H., Good P.F., Shashidharan P. TorsinA immunore-activity in inclusion bodies in trinucleotide repeat diseases. Mov Disord 2003, 18:1041-1044.
-
(2003)
Mov Disord
, vol.18
, pp. 1041-1044
-
-
Walker, R.H.1
Good, P.F.2
Shashidharan, P.3
-
127
-
-
0242382819
-
Developments in the molecular biology of DYT1 dystonia
-
Walker R.H., Shashidharan P. Developments in the molecular biology of DYT1 dystonia. Mov Disord 2003, 18:1102-1107.
-
(2003)
Mov Disord
, vol.18
, pp. 1102-1107
-
-
Walker, R.H.1
Shashidharan, P.2
-
128
-
-
0017303522
-
The structure of the ventral nerve cord of Caenorhabditis elegans
-
White J.G., Southgate E., Thomson J.N., Brenner S. The structure of the ventral nerve cord of Caenorhabditis elegans. Philos Trans R Soc Lond B Biol Sci 1976, 275:327-348.
-
(1976)
Philos Trans R Soc Lond B Biol Sci
, vol.275
, pp. 327-348
-
-
White, J.G.1
Southgate, E.2
Thomson, J.N.3
Brenner, S.4
-
129
-
-
0035032378
-
Dopamine signaling in Caenorhabditis elegans-potential for parkinsonism research
-
Wintle R.F., Van Tol H.H.M. Dopamine signaling in Caenorhabditis elegans-potential for parkinsonism research. Parkinsonism and Related Disorders 2001, 7:177-183.
-
(2001)
Parkinsonism and Related Disorders
, vol.7
, pp. 177-183
-
-
Wintle, R.F.1
Van Tol, H.H.M.2
-
130
-
-
0004291817
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
-
Wood W.B. The Nematode Caenorhabditis eleganis 1988, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
-
(1988)
The Nematode Caenorhabditis eleganis
-
-
Wood, W.B.1
-
131
-
-
0037701612
-
Huntingtin contains a highly conserved nuclear export signal
-
Xia J., Lee D.H., Taylor J., Vandelft M., Truant R. Huntingtin contains a highly conserved nuclear export signal. Hum Mol Genet 2003, 12:1393-1403.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1393-1403
-
-
Xia, J.1
Lee, D.H.2
Taylor, J.3
Vandelft, M.4
Truant, R.5
-
132
-
-
0036278335
-
Dopamine-dependent neurotoxicity of ?-synuclein: A mechanism for selective neurodegeneration in PD
-
Xu J., Kao S., Lee G.J.S., Song W., Jin L., Yankner B.A. Dopamine-dependent neurotoxicity of ?-synuclein: A mechanism for selective neurodegeneration in PD. Nat Med 2002, 8:600-606.
-
(2002)
Nat Med
, vol.8
, pp. 600-606
-
-
Xu, J.1
Kao, S.2
Lee, G.J.S.3
Song, W.4
Jin, L.5
Yankner, B.A.6
-
133
-
-
0034094873
-
Glutamine repeats and neurodegeneration
-
Zoghbi H.Y., Orr H.T. Glutamine repeats and neurodegeneration. A Rev Neurosci 2000, 23.
-
(2000)
A Rev Neurosci
, vol.23
-
-
Zoghbi, H.Y.1
Orr, H.T.2
|