Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 1, 1999, Pages 179-184

  Faber, Peter W ^a,b   Alter, Janet R ^a,b   Macdonald, Marcy E ^a   Hart, Anne C ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMINE DERIVATIVE; GREEN FLUORESCENT PROTEIN; HUNTINGTIN; HYBRID PROTEIN; POLYAMINE;

AGING; AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CAENORHABDITIS ELEGANS; CELL STRUCTURE; CELL SURVIVAL; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; NERVE CELL DEGENERATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN AGGREGATION; SENSORY NERVE CELL;

AGE FACTORS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; APOPTOSIS; BEHAVIOR, ANIMAL; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CASPASES; CYSTEINE ENDOPEPTIDASES; HELMINTH PROTEINS; HUMANS; HUNTINGTON DISEASE; NERVE TISSUE PROTEINS; NEURONS, AFFERENT; NUCLEAR PROTEINS; PEPTIDE FRAGMENTS; PEPTIDES; TOUCH;

ANIMALIA; CAENORHABDITIS ELEGANS; INVERTEBRATA;

EID: 0033524413     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.1.179     Document Type: Article

References (46)

1. Huntington's Disease Collaborative Research Group (1993) Cell 72, 971-983.
2. Strong, T. V., Tagle, D. A., Valdes, J. M., Elmer, L. W., Boehm, K., Swaroop, M., Kaatz, K. W., Collins, F. S. & Albin, R. L. (1993) Nat. Genet. 5, 259-265.
3. Martin, J. B. & Gusella, J. F. (1986) N. Engl. J. Med. 315, 1267-1276.
4. Vonsattel, J. P., Myers, R. H., Stevens, T. J., Ferrante, R. J., Bird, E. D. & Richardson, E. P., Jr. (1985) J. Neuropathol. Exp. Neurol. 44, 559-577.
5. Gusella, J. F. & MacDonald, M. E. (1995) Curr. Opin. Neurobiol. 5, 656-662.
6. La Spada, A. R., Wilson, E. M., Lubahn, D. B., Harding, A. E. & Fischbeck, K. H. (1991) Nature (London) 352, 77-79.
7. Koide, R., Ikeuchi, T., Onodera, O., Tanaka, H., Igarashi, S., Endo, K., Takahashi, H., Kondo, R., Ishikawa, A., Hayashi, T., et al. (1994) Nat. Genet. 6, 9-13.
8. Orr, H. T., Chung, M. Y., Banfi, S., Kwiatkowski, T. J., Jr., Servadio, A., Beaudet, A. L., McCall, A. E., Duvick, L. A., Ranum, L. P. & Zoghbi, H. Y. (1993) Nat. Genet. 4, 221-226.
9. Sanpei, K., Takano, H., Igarashi, S., Sato, T., Oyake, M., Sasaki, H., Wakisaka, A., Tashiro, K., Ishida, Y., Ikeuchi, T., et al. (1996) Nat. Genet. 14, 277-284.
10. Pulst, S. M., Nechiporuk, A., Nechiporuk, T., Gispert, S., Chen, X. N., Lopes-Cendes, I., Pearlman, S., Starkman, S., Orozco-Diaz, G., Lunkes, A., et al. (1996) Nat. Genet. 14, 269-276.
11. Imbert, G., Saudou, F., Yvert, G., Devys, D., Trottier, Y., Garnier, J. M., Weber, C., Mandel, J. L., Cancel, G., Abbas, N., et al. (1996) Nat. Genet. 14, 285-291.
12. Kawaguchi, Y., Okamoto, T., Taniwaki, M., Aizawa, M., Inoue, M., Katayama, S., Kawakami, H., Nakamura, S., Nishimura, M., Akiguchi, I., et al. (1994) Nat. Genet. 8, 221-228.
13. Zhuchenko, O., Bailey, J., Bonnen, P., Ashizawa, T., Stockton, D. W., Amos, C., Dobyns, W. B., Subramony, S. H., Zoghbi, H. Y. & Lee, C. C. (1997) Nat. Genet. 15, 62-69.
14. David, G., Abbas, N., Stevanin, G., Durr, A., Yvert, G., Cancel, G., Weber, C., Imbert, G., Saudou, F., Antoniou, E., et al. (1997) Nat. Genet. 17, 65-70.
15. Reddy, P. S. & Housman, D. E. (1997) Curr. Opin. Cell Biol. 9, 364-372.
16. Trottier, Y., Lutz, Y., Stevanin, G., Imbert, G., Devys, D., Cancel, G., Saudou, F., Weber, C., David, G., Tora, L., et al. (1995) Nature (London) 378, 403-406.
17. White, J. K., Auerbach, W., Duyao, M. P., Vonsattel, J. P., Gusella, J. F., Joyner, A. L. & MacDonald, M. E. (1997) Nat. Genet. 17, 404-410.
18. DiFiglia, M., Sapp, E., Chase, K. O., Davies, S. W., Bates, G. P., Vonsattel, J. P. & Aronin, N. (1997) Science 277, 1990-1993.
19. Mangiarini, L., Sathasivam, K., Seller, M., Cozens, B., Harper, A., Hetherington, C., Lawton, M., Trottier, Y., Lehrach, H., Davies, S. W. & Bates, G. P. (1996) Cell 87, 493-506.
20. Davies, S. W., Turmaine, M., Cozens, B. A., DiFiglia, M., Sharp, A. H., Ross, C. A., Scherzinger, E., Wanker, E. E., Mangiarini, L. & Bates, G. P. (1997) Cell 90, 537-548.
21. Ross, C. A. (1997) Neuron 19, 1147-1150.
22. Scherzinger, E., Lurz, R., Turmaine, M., Mangiarini, L., Hollenbach, B., Hasenbank, R., Bates, G. P., Davies, S. W., Lehrach, H. & Wanker, E. E. (1997) Cell 90, 549-558.
23. Martindale, D., Hackam, A., Wieczorek, A., Ellerby, L., Wellington, C., McCutcheon, K., Singaraja, R., Kazemi-Esfarjani, P., Devon, R., Kim, S. U., et al. (1998) Nat. Genet. 18, 150-154.
24. Cooper, J. K., Schilling, G., Peters, M. F., Herring, W. J., Sharp, A. H., Kaminsky, Z., Masone, J., Khan, F. A., Delanoy, H., Borchelt, D. R., et al. (1998) Hum. Mol. Genet. 7, 783-790.
25. Hackam, A. S., Singaraja, R., Wellington, C. L., Metzler, M., McCutcheon, K., Zhang, T., Kalchman, M. & Hayden, M. R. (1998) J. Cell Biol. 141, 1097-1105.
26. Li, S. H. & Li, X. J. (1998) Hum. Mol. Genet. 7, 777-782.
27. Hedgecock, E. M., Culotti, J. G., Thomson, J. N. & Perkins, L. A. (1985) Dev. Biol. 111, 158-170.
28. Bargmann, C. I., Thomas, J. H. & Horvitz, H. R. (1990) Cold Spring Harbor Symp. Quant. Biol. 55, 529-538.
29. Kaplan, J. M. & Horvitz, H. R. (1993) Proc. Natl. Acad. Sci. USA 90, 2227-2231.
30. Troemel, E. R., Chou, J. H., Dwyer, N. D., Colbert, H. A. & Bargmann, C. I. (1995) Cell 83, 207-218.
31. Fire, A., Harrison, S. W. & Dixon, D. (1990) Gene 93, 189-198.
32. Mello, C. & Fire, A. (1995) Methods Cell Biol. 48, 451-482.
33. Han, M. & Sternberg, P. W. (1991) Genes Dev. 5, 2188-2198.
34. Hart, A. C., Sims, S. & Kaplan, J. M. (1995) Nature (London) 378, 82-85.
35. Persichetti, F., Ambrose, C. M., Ge, P., McNeil, S. M., Srinidhi, J., Anderson, M. A., Jenkins, B., Barnes, G. T., Duyao, M. P., Kanaley, L., et al. (1995) Mol. Med. 1, 374-383.
36. Nonet, M. L., Staunton, J. E., Kilgard, M. P., Fergestad, T., Hartwieg, E., Horvitz, H. R., Jorgensen, E. M. & Meyer, B., (1997) J. Neurosci. 17, 8061-8073.
37. Perkins, L. A., Hedgecock, E. M., Thomson, J. N. & Culotti, J. G. (1986) Dev. Biol. 117, 456-487.
38. Starich, T. A., Herman, R. K., Kari, C. K., Yeh, W. H., Schackwitz, W. S., Schuyler, M. W., Collet, J., Thomas, J. H. & Riddle, D. L. (1995) Genetics 139, 171-188.
39. Hengartner, M. O. & Horvitz, H. R. (1994) Curr. Opin. Genet. Dev. 4, 581-586.
40. Burright, E. N., Clark, H. B., Servadio, A., Matilla, T., Feddersen, R. M., Yunis, W. S., Duvick, L. A., Zoghbi, H. Y. & Orr, H. T. (1995) Cell 82, 937-948.
41. Ikeda, H., Yamaguchi, M., Sugai, S., Aze, Y., Narumiya, S. & Kakizuka, A. (1996) Nat. Genet. 13, 196-202.
42. Ordway, J. M., Tallaksen-Greene, S., Gutekunst, C. A., Benstein, E. M., Cearley, J. A., Wiener, H. W., Dure, L. S. T., Lindsey, R., Hersch, S. M., Jope, R. S., et al. (1997) Cell 91, 753-763.
43. Warrick, J. M., Paulson, H. L., Gray-Board, G. L., Bui, Q. T., Fischbeck, K. H., Pittman, R. N. & Bonini, N. M. (1998) Cell 93, 939-949.
44. Jackson, G. R., Salecker, L, Dong, X., Yao, X., Arnheim, N., Faber, P. W., MacDonald, M. E. & Zipursky, S. L. (1998) Neuron 21, 633-642.
45. Dragunow, M., Faull, R. L., Lawlor, P., Beilharz, E. J., Singleton K., Walker, E. B. & Mee, E. (1995) Neuroreport 6, 1053-1057.
46. Hengartner, M. (1997) in C. elegans II, eds. Riddle, D. L. Blumenthal, T., Meyer, B. J. & Preiss, J. R. (Cold Spring Harbor Lab. Press, Plainview, NY), pp. 383-416.