-
1
-
-
0025074907
-
In vitro selection of RNA molecules that bind specific ligands
-
Ellington, A.D.; Szostak, J.W. In vitro selection of RNA molecules that bind specific ligands. Nature, 1990, 346, 818-22.
-
(1990)
Nature
, vol.346
, pp. 818-822
-
-
Ellington, A.D.1
Szostak, J.W.2
-
2
-
-
0025194307
-
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
-
Tuerk, C.; Gold, L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science, 1990, 249, 505-10.
-
(1990)
Science
, vol.249
, pp. 505-510
-
-
Tuerk, C.1
Gold, L.2
-
3
-
-
68249132689
-
Patents on SELEX and therapeutic aptamers
-
Pooja, D.; Soyoun, K; Dong-Ki, L. Patents on SELEX and Therapeutic Aptamers. Recent Patents on DNA & Gene Sequences, Volume 2, Number 3, 2008, pp. 172-186.
-
(2008)
Recent Patents on DNA & Gene Sequences
, vol.2
, Issue.3
, pp. 172-186
-
-
Pooja, D.1
Soyoun, K.2
Dong-Ki, L.3
-
4
-
-
34848813621
-
One-step selection of vaccinia virus-binding DNA aptamers by MonoLEX
-
Nitsche, A.; Kurth, A.; Dunkhorst, A.; Pänke, O.; Sielaff, H.; Junge, W.; Muth D.; Scheller, F.; Stöcklein, W.; Dahmen, C.; Pauli, G.; Kage, A. One-step selection of Vaccinia virus-binding DNA aptamers by MonoLEX. BMC Biotechnol., 2007, 7, 48-59.
-
(2007)
BMC Biotechnol.
, vol.7
, pp. 48-59
-
-
Nitsche, A.1
Kurth, A.2
Dunkhorst, A.3
Pänke, O.4
Sielaff, H.5
Junge, W.6
Muth, D.7
Scheller, F.8
Stöcklein, W.9
Dahmen, C.10
Pauli, G.11
Kage, A.12
-
5
-
-
0032539924
-
High affinity ligands from in vitro selection: Complex targets
-
DOI 10.1073/pnas.95.6.2902
-
Morris, K.N.; Jensen, K.B.; Julin, C.M.; Weil, M.; Gold, L. High affinity ligands from in vitro selection: complex targets. Proc. Natl. Acad. Sci. U. S. A., 1998, 95, 2902-2907. (Pubitemid 28135827)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.6
, pp. 2902-2907
-
-
Morris, K.N.1
Jensen, K.B.2
Julin, C.M.3
Weil, M.4
Gold, L.5
-
6
-
-
18344375927
-
Neutralizing aptamers from whole-cell SELEX inhibit the RET receptor tyrosine kinase
-
Cerchia, L.; Ducongé, F.; Pestourie, C.; Boulay, J.; Aissouni, Y.; Gombert, K.; Tavitian, B.; de Franciscis, V.; Libri D. Neutralizing aptamers from whole-cell SELEX inhibit the RET receptor tyrosine kinase. PLoS Biol., 2005, 3, e123.
-
(2005)
PLoS Biol.
, vol.3
-
-
Cerchia, L.1
Ducongé, F.2
Pestourie, C.3
Boulay, J.4
Aissouni, Y.5
Gombert, K.6
Tavitian, B.7
De Franciscis, V.8
Libri, D.9
-
7
-
-
43049143065
-
Cell-SELEX: Novel perspectives of aptamer-based therapeutics
-
DOI 10.3390/ijms9040668
-
Guo, K.T.; Ziemer, G.; Paul, A.; Wendel, H.P. CELL-SELEX: Novel perspectives of aptamer-based therapeutics. Int. J. Mol. Sci., 2008, 9, 668-678. (Pubitemid 351631122)
-
(2008)
International Journal of Molecular Sciences
, vol.9
, Issue.4
, pp. 668-678
-
-
Guo, K.-T.1
Paul, A.2
Schichor, C.3
Ziemer, G.4
Wendel, H.P.5
-
9
-
-
46049108242
-
Cell-specific internalization study of an aptamer from whole cell selection
-
Xiao, Z.; Shangguan D.; Cao Z.; Fang X.; Tan W. Cell-specific internalization study of an aptamer from whole cell selection. Chemistry, 2008, 14, 1769-75.
-
(2008)
Chemistry
, vol.14
, pp. 1769-1775
-
-
Xiao, Z.1
Shangguan, D.2
Cao, Z.3
Fang, X.4
Tan, W.5
-
10
-
-
34249870129
-
Aptamers evolved from cultured cancer cells reveal molecular differences of cancer cells in patient samples
-
DOI 10.1373/clinchem.2006.083246
-
Shangguan, D.; Cao, Z.C.; Li, Y.; Tan, W. Aptamers evolved from cultured cancer cells reveal molecular differences of cancer cells in patient samples. Clin. Chem., 2007, 53, 1153-1155. (Pubitemid 46867534)
-
(2007)
Clinical Chemistry
, vol.53
, Issue.6
, pp. 1153-1155
-
-
Shangguan, D.1
Cao, Z.C.2
Li, Y.3
Tan, W.4
-
11
-
-
67650088525
-
Identification of an aptamer targeting hnRNP A1 by tissue slide-based SELEX
-
Li, S.; Xu, H.; Ding, H.; Huang, Y.; Cao, X.; Yang, G.; Li, J.; Xie, Z.; Meng, Y.; Li, X.; Zhao, Q.; Shen B.; Shao N. Identification of an aptamer targeting hnRNP A1 by tissue slide-based SELEX. J. Pathol., 2009, 218, 327-336.
-
(2009)
J. Pathol.
, vol.218
, pp. 327-336
-
-
Li, S.1
Xu, H.2
Ding, H.3
Huang, Y.4
Cao, X.5
Yang, G.6
Li, J.7
Xie, Z.8
Meng, Y.9
Li, X.10
Zhao, Q.11
Shen, B.12
Shao, N.13
-
12
-
-
33749512390
-
A new technique for the isolation and surface immobilization of mesenchymal stem cells from whole bone marrow using high-specific DNA aptamers
-
DOI 10.1634/stemcells.2006-0015
-
Guo, K.T.; SchAfer, R.; Paul, A.; Gerber, A.; Ziemer, G.; Wendel, H.P. A new technique for the isolation and surface immobilization of mesenchymal stem cells from whole bone marrow using high-specific DNA aptamers. Stem Cells, 2006, 24, 2220-2231. (Pubitemid 44527475)
-
(2006)
Stem Cells
, vol.24
, Issue.10
, pp. 2220-2231
-
-
Guo, K.-T.1
Schafer, R.2
Paul, A.3
Gerber, A.4
Ziemer, G.5
Wendel, H.P.6
-
13
-
-
39049142223
-
Pegaptanib sodium for the treatment of age-related macular degeneration
-
DOI 10.1517/14656566.9.3.499
-
Apte R.S. Pegaptanib sodium for the treatment of age-related macular degeneration. Expert Opin. Pharmacother., 2008, 9, 499-508. (Pubitemid 351291794)
-
(2008)
Expert Opinion on Pharmacotherapy
, vol.9
, Issue.3
, pp. 499-508
-
-
Apte, R.S.1
-
14
-
-
0037213645
-
Evaluation of DNA aptamers directed to thrombin as potential thrombus imaging agents
-
DOI 10.1016/S0969-8051(02)00378-5, PII S0969805102003785
-
Dougan, H.; Weitz, J.I.; Stafford, A.R.; Gillespie, K.D.; Klement, P.; Hobbs, J.B.; Lyster, D.M. Evaluation of DNA aptamers directed to thrombin as potential thrombus imaging agents. Nucl. Med. Biol., 2003, 30, 61-72. (Pubitemid 35454163)
-
(2003)
Nuclear Medicine and Biology
, vol.30
, Issue.1
, pp. 61-72
-
-
Dougan, H.1
Weitz, J.I.2
Stafford, A.R.3
Gillespie, K.D.4
Klement, P.5
Hobbs, J.B.6
Lyster, D.M.7
-
15
-
-
77953350228
-
Current strategies to improve the efficacy and the delivery of nucleic acid based drugs
-
May
-
Grassi, M.; Cavallaro, G.; Scire, S.; Scaggiante, B.; Dapas, B.; Farra, R.; Baiz, D.; Giansante, C.; Guarnieri, G.; Perin, D.; Grassi, G. Current Strategies to Improve the Efficacy and the Delivery of Nucleic Acid Based Drugs. Current Signal Transduction Therapy, Volume 5, Number 2, May 2010, pp. 92-120.
-
(2010)
Current Signal Transduction Therapy
, vol.5
, Issue.2
, pp. 92-120
-
-
Grassi, M.1
Cavallaro, G.2
Scire, S.3
Scaggiante, B.4
Dapas, B.5
Farra, R.6
Baiz, D.7
Giansante, C.8
Guarnieri, G.9
Perin, D.10
Grassi, G.11
-
16
-
-
0033428608
-
Effect of phosphorothioate modifications on the ability of GTn oligodeoxynucleotides to specifically recognize single-stranded DNA-binding proteins and to affect human cancer cellular growth
-
DOI 10.1016/S0300-9084(99)00350-8
-
Morassutti, C.; Scaggiante, B.; Dapas, B.; Xodo, L.; Tell, G.; Quadrifoglio, F. Effect of phosphorothioate modifications on the ability of GTn oligodeoxynucleotides to specifically recognize single-stranded DNA-binding proteins and to affect human cancer cellular growth. Biochimie, 1999, 81, 1115-1122. (Pubitemid 30006551)
-
(1999)
Biochimie
, vol.81
, Issue.12
, pp. 1115-1122
-
-
Morassutti, C.1
Scaggiante, B.2
Dapas, B.3
Xodo, L.4
Tell, G.5
Quadrifoglio, F.6
-
17
-
-
0035695234
-
Alpha-anomeric configuration of GT oligodeoxynucleotide leads to loss of the specific aptameric and cytotoxic properties retained by the beta-anomeric analog
-
Scaggiante, B.; Dapas, B.; Quadrifoglio, F. Alpha-anomeric configuration of GT oligodeoxynucleotide leads to loss of the specific aptameric and cytotoxic properties retained by the beta-anomeric analog. Antisense Nucleic Acid Drug Dev., 2001, 11, 395-399. (Pubitemid 34106805)
-
(2001)
Antisense and Nucleic Acid Drug Development
, vol.11
, Issue.6
, pp. 395-399
-
-
Scaggiante, B.1
Dapas, B.2
Quadrifoglio, F.3
-
18
-
-
70349786346
-
The chemical biology of aptamers
-
Mayer, G. The chemical biology of aptamers. Angew Chem. Int. E., Engl., 2009, 48, 2672-2689.
-
(2009)
Angew Chem. Int. E., Engl.
, vol.48
, pp. 2672-2689
-
-
Mayer, G.1
-
19
-
-
27544486140
-
A versatile toolbox for variable DNA functionalization at high density
-
DOI 10.1021/ja051725b
-
Jäger, S.; Rasched, G.; Kornreich-Leshem, H.; Engeser, M.; Thum, O.; Famulok, M. A versatile toolbox for variable DNA functionali-zation at high density. J. Am. Chem. Soc., 2005, 127, 15071-15082. (Pubitemid 41547373)
-
(2005)
Journal of the American Chemical Society
, vol.127
, Issue.43
, pp. 15071-15082
-
-
Jager, S.1
Rasched, G.2
Kornreich-Leshem, H.3
Engeser, M.4
Thum, O.5
Famulok, M.6
-
20
-
-
33845939367
-
2'-deoxy purine, 2'-O-methyl pyrimidine [dRmY]aptamers as candidate therapeutics
-
Burmeister, P.E.; Wang, C.; Killough, J.R.; Lewis, S.D.; Horwitz, L.R.; Ferguson A.; Thompson, K.M.; Pendergrast, P.S.; McCauley, T.G.; Kurz, M.; Diener, J.; Cload, S.T.; Wilson, C.; Keefe, A.D. 2'-Deoxy purine, 2'-O-methyl pyrimidine [dRmY]aptamers as candidate therapeutics. Oligonucleotides, 2006, 16, 337-3351.
-
(2006)
Oligonucleotides
, vol.16
, pp. 337-3351
-
-
Burmeister, P.E.1
Wang, C.2
Killough, J.R.3
Lewis, S.D.4
Horwitz, L.R.5
Ferguson, A.6
Thompson, K.M.7
Pendergrast, P.S.8
McCauley, T.G.9
Kurz, M.10
Diener, J.11
Cload, S.T.12
Wilson, C.13
Keefe, A.D.14
-
21
-
-
46049121018
-
Polymerase chain reaction and transcription using locked nucleic acid nucleotide triphosphates
-
DOI 10.1021/ja801389n
-
Veedu, R.N.; Vester, B.; Wengel, J. Polymerase chain reaction and transcription using locked nucleic acid nucleotide triphosphates. J. Am. Chem Soc, 2008, 130, 8124-8125. (Pubitemid 351898512)
-
(2008)
Journal of the American Chemical Society
, vol.130
, Issue.26
, pp. 8124-8125
-
-
Veedu, R.N.1
Vester, B.2
Wengel, J.3
-
22
-
-
10244257661
-
Application of locked nucleic acids to improve aptamer in vivo stability and targeting function
-
DOI 10.1093/nar/gkh862
-
Schmidt, K.S.; Borkowski, S.; Kurreck, J.; Stephens, A.W.; Bald, R.; Hecht, M.; Friebe, M.; Dinkelborg, L.; Erdmann, V.A. Application of locked nucleic acids to improve aptamer in vivo stability and targeting function. Nucleic Acids Res., 2004, 32, 5757-5765. (Pubitemid 39619159)
-
(2004)
Nucleic Acids Research
, vol.32
, Issue.19
, pp. 5757-5765
-
-
Schmidt, K.S.1
Borkowski, S.2
Kurreck, J.3
Stephens, A.W.4
Bald, R.5
Hecht, M.6
Friebe, M.7
Dinkelberg, L.8
Erdmann, V.A.9
-
23
-
-
81455144711
-
Locked vs. Unlocked nucleic acids [LNA vs. UNA]: Contrasting structures work towards common therapeutic goals
-
Campbell, M.A.; Wengel, J. Locked vs. unlocked nucleic acids [LNA vs. UNA]: contrasting structures work towards common therapeutic goals. Chem. Soc. Rev., 2011, 40(12), 5680-9.
-
(2011)
Chem. Soc. Rev.
, vol.40
, Issue.12
, pp. 5680-5689
-
-
Campbell, M.A.1
Wengel, J.2
-
24
-
-
0032493654
-
165): Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain
-
DOI 10.1074/jbc.273.32.20556
-
Ruckman, J.; Green, L.S.; Beeson, J.; Waugh, S.; Gillette, W.L.; Henninger, D.D.; Claesson-Welsh, L.; Janjic, N. 2'-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor [VEGF165]. Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain. J. Biol. Chem., 1998, 273, 20556-20567. (Pubitemid 28377626)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.32
, pp. 20556-20567
-
-
Ruckman, J.1
Green, L.S.2
Beeson, J.3
Waugh, S.4
Gillette, W.L.5
Henninger, D.D.6
Claesson-Welsh, L.7
Janjic, N.8
-
25
-
-
77958109182
-
Combinatorial selection of DNA thioaptamers targeted to the HA binding domain of human CD44
-
Somasunderam, A.; Thiviyanathan, V; Tanaka, T.; Li, X.; Neerathilingam, M.; Lokesh, G.L.; Mann, A.; Peng, Y.; Ferrari, M.; Klostergaard, J.; Gorenstein, D.G. Combinatorial selection of DNA thioaptamers targeted to the HA binding domain of human CD44. Biochemistry, 2010, 49, 9106-9112.
-
(2010)
Biochemistry
, vol.49
, pp. 9106-9112
-
-
Somasunderam, A.1
Thiviyanathan, V.2
Tanaka, T.3
Li, X.4
Neerathilingam, M.5
Lokesh, G.L.6
Mann, A.7
Peng, Y.8
Ferrari, M.9
Klostergaard, J.10
Gorenstein, D.G.11
-
26
-
-
80052230213
-
Improving the stability of aptamers by chemical modification
-
Wang, R.E.; Wu, H.; Niu, Y.; Cai, J. Improving the stability of aptamers by chemical modification. Curr. Med. Chem., 2011, 8, 4126-4138.
-
(2011)
Curr. Med. Chem.
, vol.8
, pp. 4126-4138
-
-
Wang, R.E.1
Wu, H.2
Niu, Y.3
Cai, J.4
-
27
-
-
17644399512
-
Pharmacokinetics and biodistribution of novel aptamer compositions
-
DOI 10.1007/s11095-004-7676-4
-
Healy, J.M.; Lewis, S.D.; Kurz, M.; Boomer, R.M.; Thompson, K.M.; Wilson, C; McCauley, T.G. Pharmacokinetics and biodistribution of novel aptamer compositions. Pharm. Res., 2004, 21, 2234-2246. (Pubitemid 40568437)
-
(2004)
Pharmaceutical Research
, vol.21
, Issue.12
, pp. 2234-2246
-
-
Healy, J.M.1
Lewis, S.D.2
Kurz, M.3
Boomer, R.M.4
Thompson, K.M.5
Wilson, C.6
McCauley, T.G.7
-
28
-
-
32544435129
-
Pharmacologic and pharmacokinetic assessment of anti-TGFβ2 aptamers in rabbit plasma and aqueous humor
-
DOI 10.1007/s11095-005-9305-2
-
McCauley, T.G.; Kurz, J.C.; Merlino, P.G.; Lewis, S.D.; Gilbert, M.; Epstein, D.M.; Marsh, H.N. Pharmacologic and pharmacokinetic assessment of anti-TGFbeta2 aptamers in rabbit plasma and aqueous humor. Pharm. Res., 2006, 23, 303-311. (Pubitemid 43237861)
-
(2006)
Pharmaceutical Research
, vol.23
, Issue.2
, pp. 303-311
-
-
McCauley, T.G.1
Kurz, J.C.2
Merlino, P.G.3
Lewis, S.D.4
Gilbert, M.5
Epstein, D.M.6
Marsh, H.N.7
-
29
-
-
0142043453
-
Spiegelmers: Biostable aptamers
-
DOI 10.1002/cbic.200300663
-
Eulberg, D.; Klussmann, S. Spiegelmers: biostable aptamers. Chembiochem., 2003, 4 (10), 979-983. (Pubitemid 37267585)
-
(2003)
ChemBioChem
, vol.4
, Issue.10
, pp. 979-983
-
-
Eulberg, D.1
Klussmann, S.2
-
30
-
-
0037394518
-
32P-labeling of L-deoxyoligonucleotides
-
32P-labeling of L-deoxyoligonucleotides. Nucleic Acids Res., 2003, 31, e34.
-
(2003)
Nucleic Acids Res.
, vol.31
-
-
Frauendorf, C.1
Hausch, F.2
Röhl, I.3
Lichte, A.4
Vonhoff, S.5
Klussmann, S.6
-
31
-
-
0037173068
-
In vivo properties of an anti-GnRH Spiegelmer: An example of an oligonucleotide-based therapeutic substance class
-
DOI 10.1073/pnas.132067399
-
Wlotzka B.; Leva S.; Eschgfäller B.; Burmeister J.; Kleinjung F.; Kaduk C; Muhn P.; Hess-Stumpp H.; Klussmann S. In vivo properties of an anti-GnRH Spiegelmer: an example of an oligonucleo-tide-based therapeutic substance class. Proc. Natl. Acad. Sci. U. S. A., 2002, 99, 8898-8902. (Pubitemid 34693655)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.13
, pp. 8898-8902
-
-
Wlotzka, B.1
Leva, S.2
Eschgfaller, B.3
Burmeister, J.4
Kleinjung, F.5
Kaduk, C.6
Muhn, P.7
Hess-Stumpp, H.8
Klussmann, S.9
-
32
-
-
78650072690
-
Polyetheylenimine-polyplexes of spiegelmer NOX-A50 directed against intracellular high mobility group protein A1 [HMGA1] reduce tumor growth in vivo
-
Maasch C; Vater A.; Buchner K.; Purschke W.G.; Eulberg D.; Vonhoff S.; Klussmann S. Polyetheylenimine-polyplexes of Spiegelmer NOX-A50 directed against intracellular high mobility group protein A1 [HMGA1] reduce tumor growth in vivo. J. Biol. Chem., 2010, 285, 40012-40018.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 40012-40018
-
-
Maasch, C.1
Vater, A.2
Buchner, K.3
Purschke, W.G.4
Eulberg, D.5
Vonhoff, S.6
Klussmann, S.7
-
33
-
-
3843086053
-
Discriminatory aptamer reveals serum response element transcription regulated by cytohesin-2
-
DOI 10.1073/pnas.0402901101
-
Theis M.G.; Knorre A.; Kellersch B.; Moelleken J.; Wieland F.; Kolanus W.; Famulok M. Discriminatory aptamer reveals serum response element transcription regulated by cytohesin-2. Proc. Natl. Acad. Sci. U. S. A., 2004, 101, 11221-11226. (Pubitemid 39038328)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.31
, pp. 11221-11226
-
-
Theis, M.G.1
Knorre, A.2
Kellersch, B.3
Moelleken, J.4
Wieland, F.5
Kolanus, W.6
Famulok, M.7
-
34
-
-
74049099526
-
The therapeutic potential of cell-internalizing aptamers
-
Zhou J.; Rossi JJ. The therapeutic potential of cell-internalizing aptamers. Curr. Top. Med. Chem., 2009, 9, 1144-1157.
-
(2009)
Curr. Top. Med. Chem.
, vol.9
, pp. 1144-1157
-
-
Zhou, J.1
Rossi, J.J.2
-
35
-
-
76249127542
-
DNA aptamer-micelle as an efficient detection/delivery vehicle toward cancer cells
-
Wu Y.; Sefah K.; Liu H. Wang R.; Tan W. DNA aptamer-micelle as an efficient detection/delivery vehicle toward cancer cells. Proc. Natl. Acad. Sci. U. S. A., 2010, 107, 5-10.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 5-10
-
-
Wu, Y.1
Sefah, K.2
Liu, H.3
Wang, R.4
Tan, W.5
-
36
-
-
78650362849
-
Intracellular traffic of oligodeoxynucleotides in and out of the nucleus: Effect of exportins and DNA structure
-
Forsha S.J.; Panyutin I.V.; Neumann R.D.; Panyutin I.G. Intracellular traffic of oligodeoxynucleotides in and out of the nucleus: effect of exportins and DNA structure. Oligonucleotides, 2010, 20, 277-284.
-
(2010)
Oligonucleotides
, vol.20
, pp. 277-284
-
-
Forsha, S.J.1
Panyutin, I.V.2
Neumann, R.D.3
Panyutin, I.G.4
-
37
-
-
79551561775
-
Reversible targeting and controlled release delivery of daunorubicin to cancer cells by aptamer-wrapped carbon nanotubes
-
Taghdisi S.M.; Lavaee P.; Ramezani M.; Abnous K. Reversible targeting and controlled release delivery of daunorubicin to cancer cells by aptamer-wrapped carbon nanotubes. Eur. J. Pharm. Bio-pharm., 2011, 77, 200-206.
-
(2011)
Eur. J. Pharm. Bio-pharm.
, vol.77
, pp. 200-206
-
-
Taghdisi, S.M.1
Lavaee, P.2
Ramezani, M.3
Abnous, K.4
-
38
-
-
33746172167
-
Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models
-
DOI 10.1158/0008-5472.CAN-05-4199
-
Kirpotin D.B.; Drummond D.C.; Shao Y.; Shalaby M.R.; Hong K.; Nielsen U.B.; Marks J.D.; Benz CC; Park J.W. Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models. Cancer Res., 2006, 66, 6732-6740. (Pubitemid 44085631)
-
(2006)
Cancer Research
, vol.66
, Issue.13
, pp. 6732-6740
-
-
Kirpotin, D.B.1
Drummond, D.C.2
Shao, Y.3
Shalaby, M.R.4
Hong, K.5
Nielsen, U.B.6
Marks, J.D.7
Benz, C.C.8
Park, J.W.9
-
39
-
-
0033790673
-
Escort aptamers: A delivery service for diagnosis and therapy
-
Hicke B.J.; Stephens A.W. Escort aptamers: a delivery service for diagnosis and therapy. J Clin Invest., 2000, 106, 923-928.
-
(2000)
J Clin Invest.
, vol.106
, pp. 923-928
-
-
Hicke, B.J.1
Stephens, A.W.2
-
40
-
-
33845723241
-
An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform
-
DOI 10.1002/anie.200602251
-
Bagalkot V.; Farokhzad O.C; Langer R.; Jon S. An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform. Angew Chem. Int. Ed. Engl, 2006, 45, 8149-8152. (Pubitemid 44974149)
-
(2006)
Angewandte Chemie - International Edition
, vol.45
, Issue.48
, pp. 8149-8152
-
-
Bagalkot, V.1
Farokhzad, O.C.2
Langer, R.3
Jon, S.4
-
41
-
-
33646582037
-
Targeted nanoparticle-aptamer bio-conjugates for cancer chemotherapy in vivo
-
Farokhzad O.C.; Cheng J.; Teply B.A.; Sherifi I.; Jon S.; Kantoff P.W.; Richie J.P.; Langer R. Targeted nanoparticle-aptamer bio-conjugates for cancer chemotherapy in vivo. Proc. Natl. Acad. Sci. U. S. A., 2006, 103, 6315-6320.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 6315-6320
-
-
Farokhzad, O.C.1
Cheng, J.2
Teply, B.A.3
Sherifi, I.4
Jon, S.5
Kantoff, P.W.6
Richie, J.P.7
Langer, R.8
-
42
-
-
56249097260
-
Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized pt [IV] prodrug-PLGA-PEG nanoparticles
-
Dhar S.; Gu F.X.; Langer R.; Farokhzad O.C.; Lippard S.J. Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt [IV] prodrug-PLGA-PEG nanoparticles. Proc. Natl. Acad. Sci. U. S. A., 2008, 105, 17356-17361.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 17356-17361
-
-
Dhar, S.1
Gu, F.X.2
Langer, R.3
Farokhzad, O.C.4
Lippard, S.J.5
-
43
-
-
47049115502
-
Nanotechnology and aptamers: Applications in drug delivery
-
Levy-Nissenbaum E.; Radovic-Moreno A.F.; Wang A.Z.; Langer R; Farokhzad O.C. Nanotechnology and aptamers: applications in drug delivery. Trends Biotechnol., 2008, 26, 442-449.
-
(2008)
Trends Biotechnol.
, vol.26
, pp. 442-449
-
-
Levy-Nissenbaum, E.1
Radovic-Moreno, A.F.2
Wang, A.Z.3
Langer, R.4
Farokhzad, O.C.5
-
44
-
-
0347364648
-
A tenascin-C aptamer identified by tumor cell SELEX: Systematic evolution of ligands by exponential enrichment
-
DOI 10.1073/pnas.2136683100
-
Daniels D.A.; Chen H.; Hicke B.J.; Swiderek K.M.; Gold L. A tenascin-C aptamer identified by tumor cell SELEX: systematic evolution of ligands by exponential enrichment. Proc. Natl. Acad. Sci. U. S. A., 2003, 100, 15416-15421. (Pubitemid 38021004)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.26
, pp. 15416-15421
-
-
Daniels, D.A.1
Chen, H.2
Hicke, B.J.3
Swiderek, K.M.4
Gold, L.5
-
46
-
-
46049096465
-
Molecular recognition of small-cell lung cancer cells using aptamers
-
Chen H.W.; Medley C.D.; Sefah K.; Shangguan D.; Tang Z.; Meng L.; Smith J.E;. Tan W. Molecular recognition of small-cell lung cancer cells using aptamers. Chem. Med. Chem., 2008, 3, 991-1001.
-
(2008)
Chem. Med. Chem.
, vol.3
, pp. 991-1001
-
-
Chen, H.W.1
Medley, C.D.2
Sefah, K.3
Shangguan, D.4
Tang, Z.5
Meng, L.6
Smith, J.E.7
Tan, W.8
-
47
-
-
38849155858
-
Identification of liver cancer-specific aptamers using whole live cells
-
DOI 10.1021/ac701962v
-
Shangguan D.; Meng L.; Cao Z.C.; Xiao Z.; Fang X.; Li Y.; Cardona D.; Witek R.P.; Liu C.; Tan W. Identification of liver cancer-specific aptamers using whole live cells. Anal Chem., 2008, 80, 721-728. (Pubitemid 351206860)
-
(2008)
Analytical Chemistry
, vol.80
, Issue.3
, pp. 721-728
-
-
Shangguan, D.1
Meng, L.2
Cao, Z.C.3
Xiao, Z.4
Fang, X.5
Li, Y.6
Cardona, D.7
Witek, R.P.8
Liu, C.9
Tan, W.10
-
48
-
-
0037099536
-
Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen
-
Lupold S.E.; Hicke B.J.; Lin Y.; Coffey D.S. Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen. Cancer Res., 2002, 62, 4029-4033. (Pubitemid 34791070)
-
(2002)
Cancer Research
, vol.62
, Issue.14
, pp. 4029-4033
-
-
Lupold, S.E.1
Hicke, B.J.2
Lin, Y.3
Coffey, D.S.4
-
49
-
-
33745714275
-
Aptamer: Toxin conjugates that specifically target prostate tumor cells
-
Chu T.C.; Marks J.W. 3rd; Lavery L.A.; Faulkner S.; Rosenblum M.G.; Ellington A.D.; Levy M. Aptamer: toxin conjugates that specifically target prostate tumor cells. Cancer Res., 2006, 66, 5989-5992.
-
(2006)
Cancer Res.
, vol.66
, pp. 5989-5992
-
-
Chu, T.C.1
Marks III, J.W.2
Lavery, L.A.3
Faulkner, S.4
Rosenblum, M.G.5
Ellington, A.D.6
Levy, M.7
-
50
-
-
79951626552
-
Improving siRNA bio-distribution and minimizing side effects
-
Scaggiante B., Dapas B., Farra R., Grassi M., Pozzato G., Giansante C., Fiotti N., Grassi G. Improving siRNA bio-distribution and minimizing side effects. Curr. Drug Metab., 2011, 12, 11-23.
-
(2011)
Curr. Drug Metab.
, vol.12
, pp. 11-23
-
-
Scaggiante, B.1
Dapas, B.2
Farra, R.3
Grassi, M.4
Pozzato, G.5
Giansante, C.6
Fiotti, N.7
Grassi, G.8
-
51
-
-
33747031960
-
Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras
-
DOI 10.1038/nbt1223, PII NBT1223
-
McNamara J.O. 2nd; Andrechek E.R.; Wang Y.; Viles K.D.; Rempel R.E.; Gilboa E.; Sullenger B.A.; Giangrande PH. Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras. Nat. Biotechnol., 2006, 24, 1005-1015. (Pubitemid 44215395)
-
(2006)
Nature Biotechnology
, vol.24
, Issue.8
, pp. 1005-1015
-
-
McNamara II, J.O.1
Andrechek, E.R.2
Wang, Y.3
Viles, K.D.4
Rempel, R.E.5
Gilboa, E.6
Sullenger, B.A.7
Giangrande, P.H.8
-
52
-
-
70249110439
-
Systemic administration of optimized ap-tamer-siRNA chimeras promotes regression of PSMA-expressing tumors
-
Dassie J.P.; Liu X.Y.; Thomas G.S.; Whitaker R.M.; Thiel K.W.; Stockdale K.R.; Meyerholz D.K.; McCaffrey A.P.; McNamara J.O. 2nd; Giangrande P.H. Systemic administration of optimized ap-tamer-siRNA chimeras promotes regression of PSMA-expressing tumors. Nat. Biotechnol., 2009, 27, 839-849.
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 839-849
-
-
Dassie, J.P.1
Liu, X.Y.2
Thomas, G.S.3
Whitaker, R.M.4
Thiel, K.W.5
Stockdale, K.R.6
Meyerholz, D.K.7
McCaffrey, A.P.8
McNamara II, J.O.9
Giangrande, P.H.10
-
53
-
-
55449127119
-
Cell-specific induction of apoptosis by rationally designed bivalent ap-tamer-siRNA transcripts silencing Eukaryotic elongation factor 2
-
Wullner U.; Neef I.; Eller A.; Kleines M.; Tur M.K.; Barth S. Cell-specific induction of apoptosis by rationally designed bivalent ap-tamer-siRNA transcripts silencing eukaryotic elongation factor 2. Curr. Cancer Drug Target., 2008, 8, 554-565.
-
(2008)
Curr. Cancer Drug Target.
, vol.8
, pp. 554-565
-
-
Wullner, U.1
Neef, I.2
Eller, A.3
Kleines, M.4
Tur, M.K.5
Barth, S.6
-
54
-
-
77950051368
-
Prostate cancer cell death produced by the co-delivery of bcl-xL shRNA and doxorubicin using an aptamer-conjugated polyplex
-
Kim E.; Jung Y.; Choi H.; Yang J.; Suh J.S.; Huh Y.M.; Kim K.; Haam S. Prostate cancer cell death produced by the co-delivery of Bcl-xL shRNA and doxorubicin using an aptamer-conjugated polyplex. Biomaterials, 2010, 31, 4592-4599.
-
(2010)
Biomaterials
, vol.31
, pp. 4592-4599
-
-
Kim, E.1
Jung, Y.2
Choi, H.3
Yang, J.4
Suh, J.S.5
Huh, Y.M.6
Kim, K.7
Haam, S.8
-
55
-
-
76749138904
-
The formulation of aptamer-coated paclitaxel-polylactide nanoconjugates and their targeting to cancer cells
-
Tong R.; Yala L.; Fan T.M.; Cheng J. The formulation of aptamer-coated paclitaxel-polylactide nanoconjugates and their targeting to cancer cells. Biomaterials, 2010, 31, 3043-3053.
-
(2010)
Biomaterials
, vol.31
, pp. 3043-3053
-
-
Tong, R.1
Yala, L.2
Fan, T.M.3
Cheng, J.4
-
56
-
-
79952165883
-
Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo
-
Dhar S.; Kolishetti N.; Lippard S.J.; Farokhzad O.C. Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo. Proc. Natl. Acad. Sci. U. S. A., 2011, 108, 1850-1855.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 1850-1855
-
-
Dhar, S.1
Kolishetti, N.2
Lippard, S.J.3
Farokhzad, O.C.4
-
57
-
-
80054681184
-
Targeted chemoimmunotherapy using drug-loaded aptamer-dendrimer bio-conjugates
-
May 27, in press
-
Lee I.H.; An S.; Yu M.K.; Kwon H.K.; Im S.H.; Jon S. Targeted chemoimmunotherapy using drug-loaded aptamer-dendrimer bio-conjugates. J. Control. Release, 2011, May 27, in press.
-
(2011)
J. Control. Release
-
-
Lee, I.H.1
An, S.2
Yu, M.K.3
Kwon, H.K.4
Im, S.H.5
Jon, S.6
-
58
-
-
79957920185
-
Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts
-
doi: 10.1172/JCI45109
-
Ni X.; Zhang Y.; Ribas J.; Chowdhury W.H.; Castanares M.; Zhang Z.; Laiho M.; Deweese T.L.; Lupold S.E. Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts. J. Clin. Invest., 2011, http://www.jci.org, doi: 10.1172/JCI45109.
-
(2011)
J. Clin. Invest.
-
-
Ni, X.1
Zhang, Y.2
Ribas, J.3
Chowdhury, W.H.4
Castanares, M.5
Zhang, Z.6
Laiho, M.7
Deweese, T.L.8
Lupold, S.E.9
-
59
-
-
78651419151
-
Dual-aptamer-based delivery vehicle of doxorubicin to both PSMA [+]and PSMA [-] prostate cancers
-
Min K.; Jo H.; Song K.; Cho M.; Chun Y.S.; Jon S.; Kim W.J.; Ban C. Dual-aptamer-based delivery vehicle of doxorubicin to both PSMA [+]and PSMA [-] prostate cancers. Biomaterials, 2011, 32, 2124-2132.
-
(2011)
Biomaterials
, vol.32
, pp. 2124-2132
-
-
Min, K.1
Jo, H.2
Song, K.3
Cho, M.4
Chun, Y.S.5
Jon, S.6
Kim, W.J.7
Ban, C.8
-
60
-
-
0032837376
-
Nonsense-mediated mRNA decay in health and disease
-
DOI 10.1093/hmg/8.10.1893
-
Frischmeyer P.A.; Dietz H.C. Nonsense-mediated mRNA decay in health and disease. Hum. Mol. Genet., 1999, 8, 1893-1900. (Pubitemid 29458667)
-
(1999)
Human Molecular Genetics
, vol.8
, Issue.10
, pp. 1893-1900
-
-
Frischmeyer, P.A.1
Dietz, H.C.2
-
61
-
-
77952380547
-
Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay
-
Pastor F.; Kolonias D.; Giangrande P.H.; Gilboa E. Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay. Nature, 2010, 465, 227-230.
-
(2010)
Nature
, vol.465
, pp. 227-230
-
-
Pastor, F.1
Kolonias, D.2
Giangrande, P.H.3
Gilboa, E.4
-
62
-
-
38149096315
-
Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice
-
McNamara J.O.; Kolonias D.; Pastor F.; Mittler R.S.; Chen L.; Giangrande P.H.; Sullenger B.; Gilboa E. Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice. J. Clin. Invest., 2008, 118, 376-386.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 376-386
-
-
McNamara, J.O.1
Kolonias, D.2
Pastor, F.3
Mittler, R.S.4
Chen, L.5
Giangrande, P.H.6
Sullenger, B.7
Gilboa, E.8
-
63
-
-
80053576818
-
Targeting 4-1BB costimulation to disseminated tumor lesions with bi-specific oligonucleotide aptamers
-
Pastor F.; Kolonias D.; McNamara J.O.; Gilboa E. Targeting 4-1BB costimulation to disseminated tumor lesions with bi-specific oligonucleotide aptamers. Mol. Ther., 2011, 19, 1878-1886.
-
(2011)
Mol. Ther.
, vol.19
, pp. 1878-1886
-
-
Pastor, F.1
Kolonias, D.2
McNamara, J.O.3
Gilboa, E.4
-
64
-
-
0034522603
-
Human MUC1 mucin: A multifaceted glycoprotein
-
von Mensdorff-Pouilly S.; Snijdewint F.G.; Verstraeten A.A.; Verheijen R.H.; Kenemans P. Human MUC1 mucin: a multifaceted glycoprotein. Int. J. Biol. Markers, 2000, 15, 343-356. (Pubitemid 32041150)
-
(2000)
International Journal of Biological Markers
, vol.15
, Issue.4
, pp. 343-356
-
-
Von Mensdorff-Pouilly, S.1
Snijdewint, F.G.M.2
Verstraeten, A.A.3
Verheijen, R.H.M.4
Kenemans, P.5
-
65
-
-
0032852259
-
MUC1 and cancer
-
DOI 10.1016/S0925-4439(99)00055-1, PII S0925443999000551
-
Taylor-Papadimitriou J.; Burchell J.; Miles D.W.; Dalziel M. MUC1 and cancer. Biochim. Biophys. Acta, 1999, 1455, 301-313. (Pubitemid 29435996)
-
(1999)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1455
, Issue.2-3
, pp. 301-313
-
-
Taylor-Papadimitriou, J.1
Burchell, J.2
Miles, D.W.3
Dalziel, M.4
-
66
-
-
0347123435
-
Mucins in cancer: Protection and control of the cell surface
-
Hollingsworth M.A.; Swanson B.J. Mucins in cancer: protection and control of the cell surface. Nat. Rev. Cancer, 2004, 4, 45-60. (Pubitemid 38082153)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.1
, pp. 45-60
-
-
Hollingsworth, M.A.1
Swanson, B.J.2
-
67
-
-
0030829346
-
Comparison of MUC-1 mucin expression in epithelial and non-epithelial cancer cell lines and demonstration of a new short variant form (MUC-1/Z)
-
DOI 10.1002/(SICI)1097-0215(19970703)72:1<87::AID-IJC13>3.0.CO;2-7
-
Oosterkamp H.M.; Scheiner L.; Stefanova M.C.; Lloyd K.O.; Finstad C.L. Comparison of MUC-1 mucin expression in epithelial and non-epithelial cancer cell lines and demonstration of a new short variant form [MUC-1/Z]. Int. J. Cancer, 1997, 72, 87-94. (Pubitemid 27314644)
-
(1997)
International Journal of Cancer
, vol.72
, Issue.1
, pp. 87-94
-
-
Oosterkamp, H.M.1
Scheiner, L.2
Stefanova, M.C.3
Lloyd, K.O.4
Finstad, C.L.5
-
68
-
-
0035884392
-
The epithelial tumor antigen MUC1 is expressed in hematological malignancies and is recognized by MUC1-specific cytotoxic T-lymphocytes
-
Brossart P.; Schneider A.; Dill P.; Schammann T.; Grünebach F.; Wirths S.; Kanz L.; Bühring H.J.; Brugger W. The epithelial tumor antigen MUC1 is expressed in hematological malignancies and is recognized by MUC1-specific cytotoxic T-lymphocytes. Cancer Res., 2001, 61, 6846-6850. (Pubitemid 32896509)
-
(2001)
Cancer Research
, vol.61
, Issue.18
, pp. 6846-6850
-
-
Brossart, P.1
Schneider, A.2
Dill, P.3
Schammann, T.4
Grunebach, F.5
Wirths, S.6
Kanz, L.7
Buhring, H.-J.8
Brugger, W.9
-
69
-
-
33750445311
-
DNA aptamers that bind to MUC1 tumour marker: Design and characterization of MUC1-binding single-stranded DNA aptamers
-
DOI 10.1159/000096085
-
Ferreira C.S.M.; Matthews C.S.; Missailidis S. DNA Aptamers That Bind to MUC1 Tumour Marker: Design and Characterization of MUC1-Binding Single-Stranded DNA Aptamers. Tumor Biol., 2006, 27, 289-301. (Pubitemid 44646223)
-
(2006)
Tumor Biology
, vol.27
, Issue.6
, pp. 289-301
-
-
Ferreira, C.S.M.1
Matthews, C.S.2
Missailidis, S.3
-
71
-
-
38849205404
-
DNA aptamers against the MUC1 tumour marker: Design of aptamer-antibody sandwich ELISA for the early diagnosis of epithelial tumours
-
DOI 10.1007/s00216-007-1470-1, Aptamers and their applications
-
Ferreira C.S.; Papamichael K.; Guilbault G.; Schwarzacher T.; Gariepy J.; Missailidis S. DNA aptamers against the MUC1 tumour marker: design of aptamer-antibody sandwich ELISA for the early diagnosis of epithelial tumours. Anal Bioanal Chem., 2008, 390, 1039-1050. (Pubitemid 351207802)
-
(2008)
Analytical and Bioanalytical Chemistry
, vol.390
, Issue.4
, pp. 1039-1050
-
-
Ferreira, C.S.M.1
Papamichael, K.2
Guilbault, G.3
Schwarzacher, T.4
Gariepy, J.5
Missailidis, S.6
-
72
-
-
67651162036
-
Anti-MUC1 aptamers: Radiolabelling with [99m]Tc and biodistribution in MCF-7 tumour-bearing mice
-
Pieve C.D.; Perkins A.C.; Missailidis S. Anti-MUC1 aptamers: radiolabelling with [99m]Tc and biodistribution in MCF-7 tumour-bearing mice. Nucl. Med. Biol., 2009, 36, 703-710.
-
(2009)
Nucl. Med. Biol.
, vol.36
, pp. 703-710
-
-
Pieve, C.D.1
Perkins, A.C.2
Missailidis, S.3
-
73
-
-
80053903275
-
PEGylated anti-MUC1 aptamer-doxorubicin complex for targeted drug delivery to MCF7 breast cancer cells
-
Tan L.; Neoh K.G.; Kang E.T.; Choe W.S.; Su X. PEGylated anti-MUC1 aptamer-doxorubicin complex for targeted drug delivery to MCF7 breast cancer cells. Macromol. Biosci., 2011, 11, 1331-1335.
-
(2011)
Macromol. Biosci.
, vol.11
, pp. 1331-1335
-
-
Tan, L.1
Neoh, K.G.2
Kang, E.T.3
Choe, W.S.4
Su, X.5
-
74
-
-
63349112005
-
Phototoxic aptamers selectively enter and kill epithelial cancer cells
-
Ferreira C.S.; Cheung M.C.; Missailidis S.; Bisland S.; Gariépy J. Phototoxic aptamers selectively enter and kill epithelial cancer cells. Nucleic Acids Res., 2009, 37, 866-876.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 866-876
-
-
Ferreira, C.S.1
Cheung, M.C.2
Missailidis, S.3
Bisland, S.4
Gariépy, J.5
-
75
-
-
77949268954
-
Aptamer-biotin-streptavidin-C1q complexes can trigger the classical complement pathway to kill cancer cells
-
In Vitro
-
Bruno J.G. Aptamer-biotin-streptavidin-C1q complexes can trigger the classical complement pathway to kill cancer cells. In Vitro Cell Dev. Biol. Anim., 2010, 46, 107-113.
-
(2010)
Cell Dev. Biol. Anim.
, vol.46
, pp. 107-113
-
-
Bruno, J.G.1
-
76
-
-
67651003100
-
The emerging role of EpCAM in cancer and stem cell signaling
-
Munz M.; Baeuerle P.A.; Gires O. The emerging role of EpCAM in cancer and stem cell signaling. Cancer Res., 2009, 69, 5627-5629.
-
(2009)
Cancer Res.
, vol.69
, pp. 5627-5629
-
-
Munz, M.1
Baeuerle, P.A.2
Gires, O.3
-
77
-
-
77951881160
-
An open-label; randomized phase II study of adecatu-mumab; a fully human anti-epcam antibody; as monotherapy in patients with metastatic breast cancer
-
Schmidt M.; Scheulen M.E.; Dittrich C.; Obrist P.; Marschner N.; Dirix L.; Schmidt M.; Rüttinger D.; Schuler M.; Reinhardt C.; Awada A. An open-label; randomized phase II study of adecatu-mumab; a fully human anti-EpCAM antibody; as monotherapy in patients with metastatic breast cancer. Ann. Oncol., 2010, 21, 275-282.
-
(2010)
Ann. Oncol.
, vol.21
, pp. 275-282
-
-
Schmidt, M.1
Scheulen, M.E.2
Dittrich, C.3
Obrist, P.4
Marschner, N.5
Dirix, L.6
Schmidt, M.7
Rüttinger, D.8
Schuler, M.9
Reinhardt, C.10
Awada, A.11
-
78
-
-
78650991636
-
Phase II study of the human anti-epithelial cell adhesion molecule antibody adecatumumab in prostate cancer patients with increasing serum levels of prostate-specific antigen after radical prostatectomy
-
Marschner N.; Rüttinger D.; Zugmaier G.; Nemere G.; Lehmann J.; Obrist P.; Baeuerle P.A.; Wolf A.; Schmidt M.; Abrahamsson P.A.; Reinhardt C.; Heidenreich A. Phase II study of the human anti-epithelial cell adhesion molecule antibody adecatumumab in prostate cancer patients with increasing serum levels of prostate-specific antigen after radical prostatectomy. Urol. Int., 2010, 85, 386-395.
-
(2010)
Urol. Int.
, vol.85
, pp. 386-395
-
-
Marschner, N.1
Rüttinger, D.2
Zugmaier, G.3
Nemere, G.4
Lehmann, J.5
Obrist, P.6
Baeuerle, P.A.7
Wolf, A.8
Schmidt, M.9
Abrahamsson, P.A.10
Reinhardt, C.11
Heidenreich, A.12
-
79
-
-
79954858874
-
RNA aptamer against a cancer stem cell marker epithelial cell adhesion molecule
-
Shigdar S.; Lin J.; Yu Y.; Pastuovic M.; Wei M.; Duan W. RNA aptamer against a cancer stem cell marker epithelial cell adhesion molecule. Cancer Sci., 2011, 102, 991-998.
-
(2011)
Cancer Sci.
, vol.102
, pp. 991-998
-
-
Shigdar, S.1
Lin, J.2
Yu, Y.3
Pastuovic, M.4
Wei, M.5
Duan, W.6
-
81
-
-
80053334425
-
Thioaptamer conjugated liposomes for tumor vasculature targeting
-
Mann A.P.; Bhavane R.C.; Somasunderam A.; Liz Montalvo-Ortiz B.; Ghaghada K.B; Volk D.; Nieves-Alicea R.; Suh K.S; Ferrari M.; Annapragada A.; Gorenstein D.G.; Tanaka T. Thioaptamer conjugated liposomes for tumor vasculature targeting. Oncotarget, 2011, 2, 298-304.
-
(2011)
Oncotarget
, vol.2
, pp. 298-304
-
-
Mann, A.P.1
Bhavane, R.C.2
Somasunderam, A.3
Liz Montalvo-Ortiz, B.4
Ghaghada, K.B.5
Volk, D.6
Nieves-Alicea, R.7
Suh, K.S.8
Ferrari, M.9
Annapragada, A.10
Gorenstein, D.G.11
Tanaka, T.12
-
82
-
-
11344278689
-
RNA aptamers selected against the receptor activator of NF-αB acquire general affinity to proteins of the tumor necrosis factor receptor family
-
DOI 10.1093/nar/gkh949
-
Mori T.; Oguro A.; Ohtsu T.; Nakamura Y. RNA aptamers selected against the receptor activator of NF-kappaB acquire general affinity to proteins of the tumor necrosis factor receptor family. Nucleic Acids Res., 2004, 32, 6120-6128. (Pubitemid 40074006)
-
(2004)
Nucleic Acids Research
, vol.32
, Issue.20
, pp. 6120-6128
-
-
Mori, T.1
Oguro, A.2
Ohtsu, T.3
Nakamura, Y.4
-
83
-
-
70549112254
-
Using an RNA aptamer probe for flow cytometry detection of CD30-expressing lymphoma cells
-
Zhang P.; Zhao N.; Zeng Z.; Feng Y.; Tung C.H.; Chang C.C.; Zu Y. Using an RNA aptamer probe for flow cytometry detection of CD30-expressing lymphoma cells. Lab Invest., 2009, 89, 1423-1432.
-
(2009)
Lab Invest.
, vol.89
, pp. 1423-1432
-
-
Zhang, P.1
Zhao, N.2
Zeng, Z.3
Feng, Y.4
Tung, C.H.5
Chang, C.C.6
Zu, Y.7
-
84
-
-
34347396141
-
Downregulation of NPM-ALK by siRNA causes anaplastic large cell lymphoma cell growth inhibition and augments the anti cancer effects of chemotherapy in vitro
-
DOI 10.1080/07357900701206372, PII 779831627
-
Hsu F.Y.; Zhao Y.; Anderson W.F.; Johnston P.B. Downregulation of NPM-ALK by siRNA causes anaplastic large cell lymphoma cell growth inhibition and augments the anti cancer effects of chemotherapy in vitro. Cancer Invest, 2007, 25, 240-248. (Pubitemid 47026946)
-
(2007)
Cancer Investigation
, vol.25
, Issue.4
, pp. 240-248
-
-
Hsu, F.Y.-Y.1
Zhao, Y.2
Anderson, W.F.3
Johnston, P.B.4
-
85
-
-
79251568958
-
A nanocomplex that is both tumor cell-selective and cancer gene-specific for anaplastic large cell lymphoma
-
Zhao N.; Bagaria H.G.; Wong M.S.; Zu Y. A nanocomplex that is both tumor cell-selective and cancer gene-specific for anaplastic large cell lymphoma. J. Nanobiotechnol, 2011, 9, 2-12.
-
(2011)
J. Nanobiotechnol
, vol.9
, pp. 2-12
-
-
Zhao, N.1
Bagaria, H.G.2
Wong, M.S.3
Zu, Y.4
-
86
-
-
1642446081
-
Expert Review of Non-Hodgkin's Lymphomas in a Population-Based Cancer Registry: Reliability of Diagnosis and Subtype Classifications
-
DOI 10.1158/1055-9965.EPI-03-0250
-
Clarke CA.; Glaser S.L.; Dorfman R.F.; Bracci P.M.; Eberle E.; Holly E.A. Expert review of non-Hodgkin's lymphomas in a population-based cancer registry: reliability of diagnosis and subtype classifications. Cancer Epidemiol. Biomarkers Prev., 2004, 13, 138-143. (Pubitemid 38116631)
-
(2004)
Cancer Epidemiology Biomarkers and Prevention
, vol.13
, Issue.1
, pp. 138-143
-
-
Clarke, C.A.1
Glaser, S.L.2
Dorfman, R.F.3
Bracci, P.M.4
Eberle, E.5
Holly, E.A.6
-
87
-
-
38349061033
-
Aptamer directly evolved from live cells recognizes membrane bound immunoglobin heavy mu chain in Burkitt's lymphoma cells
-
Mallikaratchy P.; Tang Z.; Kwame S.; Meng L.; Shangguan D.; Tan W. Aptamer directly evolved from live cells recognizes membrane bound immunoglobin heavy mu chain in Burkitt's lymphoma cells. Mol. Cell Proteomics, 2007, 6, 2230-2238.
-
(2007)
Mol. Cell Proteomics
, vol.6
, pp. 2230-2238
-
-
Mallikaratchy, P.1
Tang, Z.2
Kwame, S.3
Meng, L.4
Shangguan, D.5
Tan, W.6
-
88
-
-
79953706298
-
A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and Leukemia
-
Mallikaratchy P.R.; Ruggiero A.; Gardner J.R.; Kuryavyi V.; Maguire W.F.; Heaney M.L.; McDevitt M.R.; Patel D.J.; Scheinberg D.A. A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia. Nucleic Acids Res., 2011, 39, 2458-2469.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 2458-2469
-
-
Mallikaratchy, P.R.1
Ruggiero, A.2
Gardner, J.R.3
Kuryavyi, V.4
Maguire, W.F.5
Heaney, M.L.6
McDevitt, M.R.7
Patel, D.J.8
Scheinberg, D.A.9
-
89
-
-
65549102827
-
Molecular assembly of an aptamer-drug conjugate for targeted drug delivery to tumor cells
-
Huang Y.F.; Shangguan D.; Liu H.; Phillips J.A.; Zhang X.; Chen Y.; Tan W. Molecular assembly of an aptamer-drug conjugate for targeted drug delivery to tumor cells. Chembiochem., 2009, 10, 862-868.
-
(2009)
Chembiochem.
, vol.10
, pp. 862-868
-
-
Huang, Y.F.1
Shangguan, D.2
Liu, H.3
Phillips, J.A.4
Zhang, X.5
Chen, Y.6
Tan, W.7
-
91
-
-
14644422666
-
Potential oncogenic action of tenascin-C in tumorigenesis
-
DOI 10.1016/j.biocel.2004.12.002
-
Orend G. Potential oncogenic action of tenascin-C in tumorigene-sis. Int. J. Biochem. Cell Biol, 2005, 37, 1066-1083. (Pubitemid 40311747)
-
(2005)
International Journal of Biochemistry and Cell Biology
, vol.37
, pp. 1066-1083
-
-
Orend, G.1
-
92
-
-
33749452709
-
Tenascin-C induced signaling in cancer
-
DOI 10.1016/j.canlet.2006.02.017, PII S0304383506001418
-
Orend G.; Chiquet-Ehrismann R. Tenascin-C induced signaling in cancer. Cancer Lett, 2006, 244, 143-163. (Pubitemid 44508708)
-
(2006)
Cancer Letters
, vol.244
, Issue.2
, pp. 143-163
-
-
Orend, G.1
Chiquet-Ehrismann, R.2
-
93
-
-
0035966106
-
Tenascin-C aptamers are generated using tumor cells and purified protein
-
Hicke B.J.; Marion C; Chang Y.F.; Gould T.; Lynott CK.; Parma D.; Schmidt P.G.; Warren S. Tenascin-C aptamers are generated using tumor cells and purified protein. J. Biol. Chem., 2001, 276, 48644-48654.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48644-48654
-
-
Hicke, B.J.1
Marion, C.2
Chang, Y.F.3
Gould, T.4
Lynott, C.K.5
Parma, D.6
Schmidt, P.G.7
Warren, S.8
-
94
-
-
33745108827
-
Tumor targeting by an aptamer
-
Hicke B.J.; Stephens A.W.; Gould T.; Chang Y.F.; Lynott CK.; Heil J.; Borkowski S.; Hilger CS.; Cook G.; Warren S.; Schmidt P.G. Tumor targeting by an aptamer. J. Nucl. Med., 2006, 47, 668-678. (Pubitemid 46768469)
-
(2006)
Journal of Nuclear Medicine
, vol.47
, Issue.4
, pp. 668-678
-
-
Hicke, B.J.1
Stephens, A.W.2
Gould, T.3
Chang, Y.-F.4
Lynott, C.K.5
Heil, J.6
Borkowski, S.7
Hilger, C.-S.8
Cook, G.9
Warren, S.10
Schmidt, P.G.11
-
95
-
-
84881631306
-
99mTc-Mercaptoacetyl-Glu-Glu-aptamer specific for tenascin-C. Molecular imaging and contrast agent database [MI-CAD] [Internet]
-
Jul 17 [updated 2008 Aug 12]
-
99mTc-Mercaptoacetyl-Glu-Glu-aptamer specific for tenascin-C. Molecular Imaging and Contrast Agent Database [MI-CAD] [Internet]. Bethesda [MD]: National Center for Biotechnology Information [US]; 2004-2010. 2008 Jul 17 [updated 2008 Aug 12].
-
(2008)
Bethesda [MD]: National Center for Biotechnology Information [US]; 2004-2010
-
-
Zhang, H.1
-
96
-
-
77956926324
-
Polylactide nanoparticles containing stably incorporated cyanine dyes for in vitro and in vivo imaging applications
-
Tong R.; Coyle V.J.; Tang L.; Barger A.M.; Fan T.M.; Cheng J. Polylactide nanoparticles containing stably incorporated cyanine dyes for in vitro and in vivo imaging applications. Microsc. Res. Tech., 2010, 73, 901-909.
-
(2010)
Microsc. Res. Tech.
, vol.73
, pp. 901-909
-
-
Tong, R.1
Coyle, V.J.2
Tang, L.3
Barger, A.M.4
Fan, T.M.5
Cheng, J.6
-
97
-
-
54849404705
-
Superparamagnetic iron oxide nanoparticle-aptamer bioconjugates for combined prostate cancer imaging and therapy
-
Wang A.Z.; Bagalkot V.; Vasilliou C.C.; Gu F.; Alexis F.; Zhang L.; Shaikh M.; Yuet K.; Cima M.J.; Langer R.; Kantoff P.W.; Bander N.H.; Jon S.; Farokhzad O.C Superparamagnetic iron oxide nanoparticle-aptamer bioconjugates for combined prostate cancer imaging and therapy. Chem. Med. Chem., 2008, 3, 1311-1315.
-
(2008)
Chem. Med. Chem.
, vol.3
, pp. 1311-1315
-
-
Wang, A.Z.1
Bagalkot, V.2
Vasilliou, C.C.3
Gu, F.4
Alexis, F.5
Zhang, L.6
Shaikh, M.7
Yuet, K.8
Cima, M.J.9
Langer, R.10
Kantoff, P.W.11
Bander, N.H.12
Jon, S.13
Farokhzad, O.C.14
-
98
-
-
79960078032
-
Tumor targeted quantum dot-mucin 1 aptamer-doxorubicin conjugate for imaging and treatment of cancer
-
Savla R.; Taratula O.; Garbuzenko O.; Minko T. Tumor targeted quantum dot-mucin 1 aptamer-doxorubicin conjugate for imaging and treatment of cancer. J Control. Release, 2011, 153(1), 16-22.
-
(2011)
J Control. Release
, vol.153
, Issue.1
, pp. 16-22
-
-
Savla, R.1
Taratula, O.2
Garbuzenko, O.3
Minko, T.4
-
99
-
-
0038476179
-
Biophysical and biological properties of quadruplex oligodeoxyribonucleotides
-
DOI 10.1093/nar/gkg316
-
Dapic V.; Abdomerovic V.; Marrington R.; Peberdy J.; Rodger A.; Trent J.O.; Bates P.J. Biophysical and biological properties of quadruplex oligodeoxyribonucleotides. Nucleic Acids Res., 2003, 31, 2097-2107. (Pubitemid 37442077)
-
(2003)
Nucleic Acids Research
, vol.31
, Issue.8
, pp. 2097-2107
-
-
Dapic, V.1
Abdomerovic, V.2
Marrington, R.3
Peberdy, J.4
Rodger, A.5
Trent, J.O.6
Bates, P.J.7
-
100
-
-
33846252731
-
Discovery and development of anticancer aptamers
-
DOI 10.1158/1535-7163.MCT-06-0172
-
Ireson CR.; Kelland L.R. Discovery and development of anticancer aptamers. Mol. Cancer Ther., 2006, 5, 2957-2962. (Pubitemid 46092036)
-
(2006)
Molecular Cancer Therapeutics
, vol.5
, Issue.12
, pp. 2957-2962
-
-
Ireson, C.R.1
Kelland, L.R.2
-
101
-
-
0033543548
-
Antiproliferative activity of G-rich oligonucleotides correlates with protein binding
-
Bates P.J.; Kahlon J.B.; Thomas S.D.; Trent J.O.; Miller D.M. Antiproliferative activity of G-rich oligonucleotides correlates with protein binding. J. Biol. Chem., 1999, 274, 26369-26377.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 26369-26377
-
-
Bates, P.J.1
Kahlon, J.B.2
Thomas, S.D.3
Trent, J.O.4
Miller, D.M.5
-
102
-
-
0037133510
-
Antiproliferative activity of G-quartet-forming oligonucleotides with backbone and sugar modifications
-
DOI 10.1021/bi0119520
-
Dapic V; Bates PJ; Trent JO; Rodger A; Thomas SD; Miller DM. Antiproliferative activity of G-quartet-forming oligonucleotides with backbone and sugar modifications. Biochemistry, 2002, 41, 3676-85. (Pubitemid 34224680)
-
(2002)
Biochemistry
, vol.41
, Issue.11
, pp. 3676-3685
-
-
Dapic, V.1
Bates, P.J.2
Trent, J.O.3
Rodger, A.4
Thomas, S.D.5
Miller, D.M.6
-
103
-
-
42049124068
-
The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells
-
DOI 10.1158/0008-5472.CAN-07-5723
-
Soundararajan S.; Chen W.; Spicer E.K.; Courtenay-Luck N.; Fernandes D.J. The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells. Cancer Res., 2008, 68, 2358-2365. (Pubitemid 351521810)
-
(2008)
Cancer Research
, vol.68
, Issue.7
, pp. 2358-2365
-
-
Soundararajan, S.1
Chen, W.2
Spicer, E.K.3
Courtenay-Luck, N.4
Fernandes, D.J.5
-
104
-
-
76749169748
-
AS-1411; a guanosine-rich oligonucleo-tide aptamer targeting nucleolin for the potential treatment of cancer; including acute myeloid Leukemia
-
Mongelard F.; Bouvet P. AS-1411; a guanosine-rich oligonucleo-tide aptamer targeting nucleolin for the potential treatment of cancer; including acute myeloid leukemia. Curr. Opin. Mol. Ther., 2010, 12, 107-114.
-
(2010)
Curr. Opin. Mol. Ther.
, vol.12
, pp. 107-114
-
-
Mongelard, F.1
Bouvet, P.2
-
106
-
-
77956243846
-
Mechanism of regulation of bcl-2 mRNA by nucleolin and A+U-rich elementbinding factor 1 [AUF1]
-
Ishimaru D.; Zuraw L.; Ramalingam S.; Sengupta T.K.; Bandyopadhyay S.; Reuben A.; Fernandes D.J.; Spicer E.K. Mechanism of regulation of bcl-2 mRNA by nucleolin and A+U-rich elementbinding factor 1 [AUF1]. J. Biol. Chem., 2010, 285, 27182-27191.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 27182-27191
-
-
Ishimaru, D.1
Zuraw, L.2
Ramalingam, S.3
Sengupta, T.K.4
Bandyopadhyay, S.5
Reuben, A.6
Fernandes, D.J.7
Spicer, E.K.8
-
107
-
-
33646845245
-
Update on the first phase I study of AGRO100 in advanced cancer
-
Laber D.A.; Sharma V.R.; Bhupalam L.; Taft B.; Hendler F.J.; Barnhart K.M. Update on the first phase I study of AGRO100 in advanced cancer. J. Clin. Oncol., 2005, 23, 3064.
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 3064
-
-
Laber, D.A.1
Sharma, V.R.2
Bhupalam, L.3
Taft, B.4
Hendler, F.J.5
Barnhart, K.M.6
-
108
-
-
67349167635
-
Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer
-
Bates P.J.; Laber D.A.; Miller D.M.; Thomas S.D.; Trent J.O. Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer. Exp. Mol. Pathol., 2009, 86, 151-164.
-
(2009)
Exp. Mol. Pathol.
, vol.86
, pp. 151-164
-
-
Bates, P.J.1
Laber, D.A.2
Miller, D.M.3
Thomas, S.D.4
Trent, J.O.5
-
109
-
-
77952369108
-
Nucleolin on the cell surface as a new molecular target for gastric cancer treatment
-
Watanabe T.; Hirano K.; Takahashi A.; Yamaguchi K.; Beppu M. Fujiki H.; Suganuma M. Nucleolin on the cell surface as a new molecular target for gastric cancer treatment. Biol. Pharm. Bull., 2010, 33, 796-803.
-
(2010)
Biol. Pharm. Bull.
, vol.33
, pp. 796-803
-
-
Watanabe, T.1
Hirano, K.2
Takahashi, A.3
Yamaguchi, K.4
Beppu, M.5
Fujiki, H.6
Suganuma, M.7
-
110
-
-
35948945681
-
AS1411 alters the localization of a complex containing protein arginine methyltransferase 5 and nucleolin
-
DOI 10.1158/0008-5472.CAN-06-4206
-
Teng Y; Girvan AC; Casson LK; Pierce WM Jr; Qian M; Thomas SD; Bates PJ. AS1411 alters the localization of a complex containing protein arginine methyltransferase 5 and nucleolin. Cancer Res., 2007, 67, 10491-500. (Pubitemid 350070825)
-
(2007)
Cancer Research
, vol.67
, Issue.21
, pp. 10491-10500
-
-
Teng, Y.1
Girvan, A.C.2
Casson, L.K.3
Pierce Jr., W.M.4
Qian, M.5
Thomas, S.D.6
Bates, P.J.7
-
111
-
-
78449269097
-
A new paradigm for ap-tamer therapeutic AS1411 action: Uptake by macropinocytosis and its stimulation by a nucleolin-dependent mechanism
-
Reyes-Reyes E.M.; Teng Y.; Bates PJ. A new paradigm for ap-tamer therapeutic AS1411 action: uptake by macropinocytosis and its stimulation by a nucleolin-dependent mechanism. Cancer Res., 2010, 70, 8617-8629.
-
(2010)
Cancer Res.
, vol.70
, pp. 8617-8629
-
-
Reyes-Reyes, E.M.1
Teng, Y.2
Bates, P.J.3
-
112
-
-
70350438402
-
Plasma membrane nucleolin is a receptor for the anticancer aptamer AS1411 in MV4-11 Leukemia cells
-
Soundararajan S.; Wang L.; Sridharan V.; Chen W.; Courtenay-Luck N.; Jones D.; Spicer E.K.; Fernandes D.J. Plasma membrane nucleolin is a receptor for the anticancer aptamer AS1411 in MV4-11 leukemia cells. Mol. Pharmacol., 2009, 76, 984-991.
-
(2009)
Mol. Pharmacol.
, vol.76
, pp. 984-991
-
-
Soundararajan, S.1
Wang, L.2
Sridharan, V.3
Chen, W.4
Courtenay-Luck, N.5
Jones, D.6
Spicer, E.K.7
Fernandes, D.J.8
-
113
-
-
70349898026
-
Reversible cell-specific drug delivery with aptamer-functionalized liposomes
-
Cao Z.; Tong R.; Mishra A.; Xu W.; Wong G.C.; Cheng J.; Lu Y. Reversible cell-specific drug delivery with aptamer-functionalized liposomes. Angew Chem. Int. Ed. Engl., 2009, 48, 6494-6498.
-
(2009)
Angew Chem. Int. Ed. Engl.
, vol.48
, pp. 6494-6498
-
-
Cao, Z.1
Tong, R.2
Mishra, A.3
Xu, W.4
Wong, G.C.5
Cheng, J.6
Lu, Y.7
-
114
-
-
79951581134
-
A graphene functionalized electrochemical aptasensor for selective label-free detection of cancer cells
-
Feng L.; Chen Y.; Ren J.; Qu X. A graphene functionalized electrochemical aptasensor for selective label-free detection of cancer cells. Biomaterials, 2011, 32, 2930-2937.
-
(2011)
Biomaterials
, vol.32
, pp. 2930-2937
-
-
Feng, L.1
Chen, Y.2
Ren, J.3
Qu, X.4
-
115
-
-
80051817418
-
Aptamer-functionalized PEG-PLGA nanoparti-cles for enhanced anti-glioma drug delivery
-
Guo J.; Gao X.; Su L.; Xia H.; Gu G.; Pang Z.; Jiang X.; Yao L.; Chen J.; Chen H. Aptamer-functionalized PEG-PLGA nanoparti-cles for enhanced anti-glioma drug delivery. Biomaterials, 2011, 32, 8010-8120.
-
(2011)
Biomaterials
, vol.32
, pp. 8010-8120
-
-
Guo, J.1
Gao, X.2
Su, L.3
Xia, H.4
Gu, G.5
Pang, Z.6
Jiang, X.7
Yao, L.8
Chen, J.9
Chen, H.10
-
116
-
-
84855949104
-
DNA G-quadruplex-templated formation of the fluorescent silver nanocluster and its application to bioimaging
-
Ai J.; Guo W.; Li B.; Li T.; Li D.; Wang E. DNA G-quadruplex-templated formation of the fluorescent silver nanocluster and its application to bioimaging. Talanta, 2012, 88, 450-455.
-
(2012)
Talanta
, vol.88
, pp. 450-455
-
-
Ai, J.1
Guo, W.2
Li, B.3
Li, T.4
Li, D.5
Wang, E.6
-
117
-
-
0027421389
-
Interaction of the Neu/p185 and EGF receptor tyrosine kinases: Implications for cellular transformation and tumor therapy
-
Dougall W.C.; Qian X.; Greene M.I. Interaction of the neu/p185 and EGF receptor tyrosine kinases: implications for cellular transformation and tumor therapy. J. Cell Biochem., 1993, 53, 61-73. (Pubitemid 23287334)
-
(1993)
Journal of Cellular Biochemistry
, vol.53
, Issue.1
, pp. 61-73
-
-
Dougall, W.C.1
Qian, X.2
Greene, M.I.3
-
118
-
-
0035135632
-
Coexpression patterns of EGFR, HER2, HER3 and HER4 in non-melanoma skin cancer
-
DOI 10.1016/S0959-8049(00)00364-6, PII S0959804900003646
-
Krähn G.; Leiter U.; Kaskel P.; Udart M.; Utikal J.; Bezold G.; Peter R.U. Coexpression patterns of EGFR; HER2; HER3 and HER4 in non-melanoma skin cancer. Eur. J. Cancer, 2001, 37, 251-259. (Pubitemid 32144704)
-
(2001)
European Journal of Cancer
, vol.37
, Issue.2
, pp. 251-259
-
-
Krahn, G.1
Leiter, U.2
Kaskel, P.3
Udart, M.4
Utikal, J.5
Bezold, G.6
Peter, R.U.7
-
119
-
-
0034597662
-
Enhanced drug resistance in cells coexpressing ErbB2 with EGF receptor or ErbB3
-
Chen X.; Yeung T.K.; Wang Z. Enhanced drug resistance in cells coexpressing ErbB2 with EGF receptor or ErbB3. Biochem. Bio-phys. Res. Commun., 2000, 277, 757-763.
-
(2000)
Biochem. Bio-phys. Res. Commun.
, vol.277
, pp. 757-763
-
-
Chen, X.1
Yeung, T.K.2
Wang, Z.3
-
120
-
-
0041923790
-
Inhibition of heregulin signaling by an aptamer that preferentially binds to the oligomeric form of human epidermal growth factor receptor-3
-
DOI 10.1073/pnas.1332660100
-
Chen C.H.; Chernis G.A.; Hoang V.Q.; Landgraf R. Inhibition of heregulin signaling by an aptamer that preferentially binds to the oligomeric form of human epidermal growth factor receptor-3. Proc. Natl. Acad. Sci. U. S. A., 2003, 100, 9226-9231. (Pubitemid 37033911)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.16
, pp. 9226-9231
-
-
Chen, C.-H.B.1
Chernis, G.A.2
Hoang, V.Q.3
Landgraf, R.4
-
121
-
-
80051734768
-
Generation of an enriched pool of DNA aptamers for an HER2-overexpressing cell line selected by cell SELEX
-
Dastjerdi K.; Tabar G.H.; Dehghani H.; Haghparast A. Generation of an enriched pool of DNA aptamers for an HER2-overexpressing cell line selected by Cell SELEX. Biotechnol. Appl. Biochem., 2011, 58, 226-230.
-
(2011)
Biotechnol. Appl. Biochem.
, vol.58
, pp. 226-230
-
-
Dastjerdi, K.1
Tabar, G.H.2
Dehghani, H.3
Haghparast, A.4
-
122
-
-
0033729031
-
Multiple endocrine neoplasia type 2 and RET: From neoplasia to neurogenesis
-
Hansford J.R.; Mulligan L.M. Multiple endocrine neoplasia type 2 and RET: from neoplasia to neurogenesis. J. Med. Genet., 2000, 37, 817-827.
-
(2000)
J. Med. Genet.
, vol.37
, pp. 817-827
-
-
Hansford, J.R.1
Mulligan, L.M.2
-
123
-
-
55749114762
-
Distribution and bioactivity of the ret-specific D4 aptamer in three-dimensional collagen gel cultures
-
Vento M.T.; Iuorio M.; Netti P.A.; Ducongè F.; Tavitian B.; Franciscis V.; Cerchia L. Distribution and bioactivity of the Ret-specific D4 aptamer in three-dimensional collagen gel cultures. Mol. Cancer Ther., 2008, 7, 3381-3388.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 3381-3388
-
-
Vento, M.T.1
Iuorio, M.2
Netti, P.A.3
Ducongè, F.4
Tavitian, B.5
Franciscis, V.6
Cerchia, L.7
-
124
-
-
33751002652
-
Effect of pharmacologic plasminogen activator inhibitor-1 inhibition on cell motility and tumor angiogenesis
-
DOI 10.1111/j.1538-7836.2006.02244.x
-
Leik C.E.; Su E.J.; Nambi P.; Crandall D.L.; Lawrence D.A. Effect of pharmacologic plasminogen activator inhibitor-1 inhibition on cell motility and tumor angiogenesis. J. Thromb. Haemost,. 2006, 4, 2710-2715. (Pubitemid 44741569)
-
(2006)
Journal of Thrombosis and Haemostasis
, vol.4
, Issue.12
, pp. 2710-2715
-
-
Leik, C.E.1
Su, E.J.2
Nambi, P.3
Crandall, D.L.4
Lawrence, D.A.5
-
125
-
-
0037175016
-
Plasminogen activator inhibitor-1 and -3 increase cell adhesion and motility of MDA-MB-435 breast cancer cells
-
DOI 10.1074/jbc.M202333200
-
Palmieri D.; Lee J.W.; Juliano R.L;. Church F.C. Plasminogen activator inhibitor-1 and -3 increase cell adhesion and motility of MDA-MB-435 breast cancer cells. J. Biol. Chem., 2002, 277, 40950-40957. (Pubitemid 35215683)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.43
, pp. 40950-40957
-
-
Palmieri, D.1
Lee, J.W.2
Juliano, R.L.3
Church, F.C.4
-
127
-
-
77952348327
-
RNA aptamers as conformational probes and regulatory agents for plasminogen activator inhibitor-1
-
Madsen J.B; Dupont D.M.; Andersen T.B.; Nielsen A.F.; Sang L.; Brix D.M.; Jensen J.K.; Broos T.; Hendrickx M.L.; Christensen A.; Kjems J.; Andreasen P.A. RNA aptamers as conformational probes and regulatory agents for plasminogen activator inhibitor-1. Biochemistry, 2010, 49, 4103-4115.
-
(2010)
Biochemistry
, vol.49
, pp. 4103-4115
-
-
Madsen, J.B.1
Dupont, D.M.2
Andersen, T.B.3
Nielsen, A.F.4
Sang, L.5
Brix, D.M.6
Jensen, J.K.7
Broos, T.8
Hendrickx, M.L.9
Christensen, A.10
Kjems, J.11
Andreasen, P.A.12
-
128
-
-
41349089301
-
Impact of vessel maturation on antiangiogenic therapy in ovarian cancer
-
Lu C.; Thaker P.H.; Lin Y.G.; Spannuth W.; Landen C.N.; Merritt W.M.; Jennings N.B.; Langley R.R.; Gershenson D.M.; Yancopoulos G.D.; Ellis L.M.; Jaffe R.B.; Coleman R.L.; Sood A.K. Impact of vessel maturation on antiangiogenic therapy in ovarian cancer. Am. J. Obstet. Gynecol., 2008, 198, 477.e1-47810.
-
(2008)
Am. J. Obstet. Gynecol.
, vol.198
-
-
Lu, C.1
Thaker, P.H.2
Lin, Y.G.3
Spannuth, W.4
Landen, C.N.5
Merritt, W.M.6
Jennings, N.B.7
Langley, R.R.8
Gershenson, D.M.9
Yancopoulos, G.D.10
Ellis, L.M.11
Jaffe, R.B.12
Coleman, R.L.13
Sood, A.K.14
-
129
-
-
34547637867
-
Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102
-
DOI 10.1158/0008-5472.CAN-07-0293
-
Sennino B.; Falcon B.L.; McCauley D.; Le T.; McCauley T.; Kurz J.C.; Haskell A.; Epstein D.M.; McDonald D.M. Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102. Cancer Res., 2007, 67, 7358-7367. (Pubitemid 47206566)
-
(2007)
Cancer Research
, vol.67
, Issue.15
, pp. 7358-7367
-
-
Sennino, B.1
Falcon, B.L.2
McCauley, D.3
Le, T.4
McCauley, T.5
Kurz, J.C.6
Haskell, A.7
Epstein, D.M.8
McDonald, D.M.9
-
130
-
-
77953604802
-
Targeting pericytes with a PDGF-B aptamer in human ovarian carcinoma models
-
Lu C.; Shahzad M.M.; Moreno-Smith M.; Lin Y.G.; Jennings N.B.; Allen J.K.; Landen C.N.; Mangala L.S.; Armaiz-Pena G.N.; Schmandt R.; Nick A.M.; Stone R.L.; Jaffe R.B.; Coleman R.L.; Sood A.K. Targeting pericytes with a PDGF-B aptamer in human ovarian carcinoma models. Cancer Biol. Ther., 2010, 9, 176-182.
-
(2010)
Cancer Biol. Ther.
, vol.9
, pp. 176-182
-
-
Lu, C.1
Shahzad, M.M.2
Moreno-Smith, M.3
Lin, Y.G.4
Jennings, N.B.5
Allen, J.K.6
Landen, C.N.7
Mangala, L.S.8
Armaiz-Pena, G.N.9
Schmandt, R.10
Nick, A.M.11
Stone, R.L.12
Jaffe, R.B.13
Coleman, R.L.14
Sood, A.K.15
-
131
-
-
79959384972
-
Increased vascular delivery and efficacy of chemotherapy after inhibition of platelet-derived growth factor-B
-
Falcon B.L.; Pietras K.; Chou J.; Chen D.; Sennino B.; Hanahan D.; McDonald D.M. Increased vascular delivery and efficacy of chemotherapy after inhibition of platelet-derived growth factor-B. Am J. Pathol., 2011, 178, 2920-2930.
-
(2011)
Am J. Pathol.
, vol.178
, pp. 2920-2930
-
-
Falcon, B.L.1
Pietras, K.2
Chou, J.3
Chen, D.4
Sennino, B.5
Hanahan, D.6
McDonald, D.M.7
-
132
-
-
27744539110
-
Targeted inhibition of αvβ3 integrin with an RNA aptamer impairs endothelial cell growth and survival
-
DOI 10.1016/j.bbrc.2005.10.043, PII S0006291X05022734
-
Mi J.; Zhang X.; Giangrande P.H.; McNamara J.O. 2nd; Nimjee S.M.; Sarraf-Yazdi S.; Sullenger B.A.; Clary B.M. Targeted inhibition of alphavbeta3 integrin with an RNA aptamer impairs endothe-lial cell growth and survival. Biochem. Biophys. Res. Commun., 2005, 338, 956-963. (Pubitemid 41597735)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.338
, Issue.2
, pp. 956-963
-
-
Mi, J.1
Zhang, X.2
Giangrande, P.H.3
McNamara II, J.O.4
Nimjee, S.M.5
Sarraf-Yazdi, S.6
Sullenger, B.A.7
Clary, B.M.8
-
133
-
-
58149339629
-
A nuclease-resistant RNA aptamer specifically inhibits angiopoietin-1-mediated tie2 activation and function
-
White R.R.; Roy J.A.; Viles K.D.; Sullenger B.A.; Kontos C.D. A nuclease-resistant RNA aptamer specifically inhibits angiopoietin-1-mediated Tie2 activation and function. Angiogenesis, 2008, 11, 395-401.
-
(2008)
Angiogenesis
, vol.11
, pp. 395-401
-
-
White, R.R.1
Roy, J.A.2
Viles, K.D.3
Sullenger, B.A.4
Kontos, C.D.5
-
134
-
-
41149139073
-
Inhibition of In Vivo Tumor Angiogenesis and Growth Via Systemic Delivery of an Angiopoietin 2-Specific RNA Aptamer
-
DOI 10.1016/j.jss.2007.04.028, PII S0022480407003198
-
Sarraf-Yazdi S.; Mi J.; Moeller B.J.; Niu X.; White R.R.; Kontos C.D.; Sullenger B.A.; Dewhirst M.W.; Clary B.M. Inhibition of in vivo tumor angiogenesis and growth via systemic delivery of an angiopoietin 2-specific RNA aptamer. J. Surg. Res., 2008, 146, 16-23. (Pubitemid 351442931)
-
(2008)
Journal of Surgical Research
, vol.146
, Issue.1
, pp. 16-23
-
-
Sarraf-Yazdi, S.1
Mi, J.2
Moeller, B.J.3
Niu, X.4
White, R.R.5
Kontos, C.D.6
Sullenger, B.A.7
Dewhirst, M.W.8
Clary, B.M.9
-
135
-
-
0030895244
-
In vivo inhibition of CD44 limits intra-abdominal spread of a human ovarian cancer xenograft in nude mice: A novel role for CD44 in the process of peritoneal implantation
-
Strobel T.; Swanson L.; Cannistra S.A. In vivo inhibition of CD44 limits intra-abdominal spread of a human ovarian cancer xenograft in nude mice: a novel role for CD44 in the process of peritoneal implantation. Cancer Res., 1997, 57, 1228-1232. (Pubitemid 27152541)
-
(1997)
Cancer Research
, vol.57
, Issue.7
, pp. 1228-1232
-
-
Strobel, T.1
Swanson, L.2
Cannistra, S.A.3
-
136
-
-
63449101042
-
Low molecular weight hyaluronan inhibits colorectal carcinoma growth by decreasing tumor cell proliferation and stimulating immune response
-
Alaniz L.; Rizzo M.; Malvicini M.; Jaunarena J.; Avella D.; Atorrasagasti C.; Aquino J.B.; Garcia M.; Matar P.; Silva M.; Mazzolini G. Low molecular weight hyaluronan inhibits colorectal carcinoma growth by decreasing tumor cell proliferation and stimulating immune response. Cancer Lett., 2009, 278, 9-16.
-
(2009)
Cancer Lett.
, vol.278
, pp. 9-16
-
-
Alaniz, L.1
Rizzo, M.2
Malvicini, M.3
Jaunarena, J.4
Avella, D.5
Atorrasagasti, C.6
Aquino, J.B.7
Garcia, M.8
Matar, P.9
Silva, M.10
Mazzolini, G.11
-
137
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
DOI 10.1016/j.cell.2008.03.027, PII S0092867408004443
-
Mani S.A.; Guo W.; Liao M.J.; Eaton E.N.; Ayyanan A.; Zhou A.Y.; Brooks M.; Reinhard F.; Zhang C.C.; Shipitsin M.; Campbell L.L.; Polyak K.; Brisken C.; Yang J.; Weinberg R.A. The epithe-lial-mesenchymal transition generates cells with properties of stem cells. Cell, 2008, 133, 704-715. (Pubitemid 351636299)
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.-J.3
Eaton, E.Ng.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
Yang, J.14
Weinberg, R.A.15
-
138
-
-
6344258588
-
The role of osteopontin in tumor metastasis
-
DOI 10.1016/j.jss.2004.03.028, PII S0022480404001362
-
Wai P.Y.; Kuo P.C. The role of Osteopontin in tumor metastasis. J. Surg. Res., 2004, 121, 228-241. (Pubitemid 39387464)
-
(2004)
Journal of Surgical Research
, vol.121
, Issue.2
, pp. 228-241
-
-
Wai, P.Y.1
Kuo, P.C.2
-
139
-
-
58149240891
-
RNA aptamer blockade of osteopontin inhibits growth and metastasis of MDA-MB231 breast cancer cells
-
Mi Z.; Guo H.; Russell M.B.; Liu Y.; Sullenger B.A.; Kuo P.C. RNA aptamer blockade of osteopontin inhibits growth and metastasis of MDA-MB231 breast cancer cells. Mol. Ther., 2009, 17, 153-161.
-
(2009)
Mol. Ther.
, vol.17
, pp. 153-161
-
-
Mi, Z.1
Guo, H.2
Russell, M.B.3
Liu, Y.4
Sullenger, B.A.5
Kuo, P.C.6
-
140
-
-
79960919903
-
Pharmacokinetic characterization of an RNA aptamer against os-teopontin and demonstration of in vivo efficacy in reversing growth of human breast cancer cells
-
Talbot L.J.; Mi Z.; Bhattacharya S.D.; Kim V.; Guo H.; Kuo P.C. Pharmacokinetic characterization of an RNA aptamer against os-teopontin and demonstration of in vivo efficacy in reversing growth of human breast cancer cells. Surgery, 2011, 150, 224-230.
-
(2011)
Surgery
, vol.150
, pp. 224-230
-
-
Talbot, L.J.1
Mi, Z.2
Bhattacharya, S.D.3
Kim, V.4
Guo, H.5
Kuo, P.C.6
-
142
-
-
84855846614
-
Osteopontin regulates epithelial mesenchymal transition-associated growth of hepatocellular cancer in a mouse xenograft model
-
Bhattacharya S.D.; Mi Z.; Kim V.M.; Guo H.; Talbot L.J.; Kuo P.C. Osteopontin regulates epithelial mesenchymal transition-associated growth of hepatocellular cancer in a mouse xenograft model. Ann. Surg., 2012, 255, 319-325.
-
(2012)
Ann. Surg.
, vol.255
, pp. 319-325
-
-
Bhattacharya, S.D.1
Mi, Z.2
Kim, V.M.3
Guo, H.4
Talbot, L.J.5
Kuo, P.C.6
-
143
-
-
34247389227
-
Phase II trial of a toll-like receptor 9-activating oligonucleotide in patients with metastatic melanoma
-
DOI 10.1200/JCO.2006.07.9129
-
Pashenkov M.; Goëss G.; Wagner C.; Hörmann M.; Jandl T.; Moser A.; Britten C.M.; Smolle J.; Koller S.; Mauch C.; Tantcheva-Poor I.; Grabbe S.;
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.36
, pp. 5716-5724
-
-
Pashenkov, M.1
Goess, G.2
Wagner, C.3
Hormann, M.4
Jandl, T.5
Moser, A.6
Britten, C.M.7
Smolle, J.8
Koller, S.9
Mauch, C.10
Tantcheva-Poor, I.11
Grabbe, S.12
Loquai, C.13
Esser, S.14
Franckson, T.15
Schneeberger, A.16
Haarmann, C.17
Krieg, A.M.18
Stingl, G.19
Wagner, S.N.20
more..
-
144
-
-
84863393261
-
A phase I clinical trial of CpG oligonucleotide 7909 [PF-03512676] in patients with previously treated chronic lymphocytic leukemia
-
sept. 19, in press
-
Zent C.S.; Smith B.J.; Ballas Z.K.; Wooldridge J.E.; Link B.K.; Call T.G.; Shanafelt T.D.; Bowen D.A.; Kay N.E.; Witzig T.E.; Weiner G.J. A Phase I Clinical Trial of CpG Oligonucleotide 7909 [PF-03512676] in Patients with Previously Treated Chronic Lymphocytic Leukemia. Leuk Lymphoma, 2011, sept. 19, in press.
-
(2011)
Leuk Lymphoma
-
-
Zent, C.S.1
Smith, B.J.2
Ballas, Z.K.3
Wooldridge, J.E.4
Link, B.K.5
Call, T.G.6
Shanafelt, T.D.7
Bowen, D.A.8
Kay, N.E.9
Witzig, T.E.10
Weiner, G.J.11
-
145
-
-
74049140005
-
In vivo selection of tumor-targeting RNA motifs
-
Mi J.; Liu Y.; Rabbani Z.N.; Yang Z.; Urban J.H.; Sullenger B.A.; Clary B.M. In vivo selection of tumor-targeting RNA motifs. Nat. Chem. Biol., 2010, 6, 22-24.
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 22-24
-
-
Mi, J.1
Liu, Y.2
Rabbani, Z.N.3
Yang, Z.4
Urban, J.H.5
Sullenger, B.A.6
Clary, B.M.7
-
146
-
-
78649937056
-
Metastasis-focused cell-based SELEX generates aptamers inhibiting cell migration and invasion
-
Zueva E.; Rubio L.I.; Ducongé F.; Tavitian B. Metastasis-focused cell-based SELEX generates aptamers inhibiting cell migration and invasion. Int. J. Cancer, 2011, 128, 797-804.
-
(2011)
Int. J. Cancer
, vol.128
, pp. 797-804
-
-
Zueva, E.1
Rubio, L.I.2
Ducongé, F.3
Tavitian, B.4
-
147
-
-
85011937534
-
In vitro selected RNA aptamer recognizing glutathione induces ROS mediated apoptosis in the human breast cancer cell line MCF 7
-
Bala J.; Bhaskar A. Varshney A.; Singh A.K.; Dey S.; Yadava P. In vitro selected RNA aptamer recognizing glutathione induces ROS mediated apoptosis in the human breast cancer cell line MCF 7. RNA Biol., 2011, 8, 101-111.
-
(2011)
RNA Biol.
, vol.8
, pp. 101-111
-
-
Bala, J.1
Bhaskar, A.2
Varshney, A.3
Singh, A.K.4
Dey, S.5
Yadava, P.6
-
148
-
-
16644376270
-
Targeting ku protein for sensitizing of breast cancer cells to DNA-damage
-
Zhang L.; Yoo S.; Dritschilo A.; Belyaev I.; Soldatenkov V. Targeting Ku protein for sensitizing of breast cancer cells to DNA-damage. Int. J. Mol. Med., 2004, 14, 153-159.
-
(2004)
Int. J. Mol. Med.
, vol.14
, pp. 153-159
-
-
Zhang, L.1
Yoo, S.2
Dritschilo, A.3
Belyaev, I.4
Soldatenkov, V.5
-
149
-
-
77953485565
-
Molecular pathways linking inflammation and cancer
-
Mantovani A. Molecular pathways linking inflammation and cancer. Curr. Mol. Med., 2010, 10, 369-373.
-
(2010)
Curr. Mol. Med.
, vol.10
, pp. 369-373
-
-
Mantovani, A.1
-
150
-
-
37549033098
-
RNA aptamer-targeted inhibition of NF-kappa B suppresses non-small cell lung cancer resistance to doxorubicin
-
Mi J.; Zhang X.; Rabbani Z.N.; Liu Y.; Reddy S.K.; Su Z.; Salahuddin F.K.; Viles K.; Giangrande P.H.; Dewhirst M.W.; Sullenger B.A.; Kontos C.D.; Clary B.M. RNA aptamer-targeted inhibition of NF-kappa B suppresses non-small cell lung cancer resistance to doxorubicin. Mol. Ther., 2008, 16, 66-73.
-
(2008)
Mol. Ther.
, vol.16
, pp. 66-73
-
-
Mi, J.1
Zhang, X.2
Rabbani, Z.N.3
Liu, Y.4
Reddy, S.K.5
Su, Z.6
Salahuddin, F.K.7
Viles, K.8
Giangrande, P.H.9
Dewhirst, M.W.10
Sullenger, B.A.11
Kontos, C.D.12
Clary, B.M.13
-
151
-
-
33645004116
-
Co-expression of anti-NFkappaB RNA aptamers and siRNAs leads to maximal suppression of NFkappaB activity in Mammalian cells
-
Chan R.; Gilbert M.; Thompson K.M.; Marsh H.N.; Epstein D.M.; Pendergrast P.S. Co-expression of anti-NFkappaB RNA aptamers and siRNAs leads to maximal suppression of NFkappaB activity in mammalian cells. Nucleic Acids Res., 2006, 34, e36.
-
(2006)
Nucleic Acids Res.
, vol.34
-
-
Chan, R.1
Gilbert, M.2
Thompson, K.M.3
Marsh, H.N.4
Epstein, D.M.5
Pendergrast, P.S.6
-
152
-
-
44149087131
-
Selection and characterization of anti-NF-αB p65 RNA aptamers
-
DOI 10.1261/rna.878908
-
Wurster S.E.; Maher L.J. 3rd. Selection and characterization of anti-NF-kappaB p65 RNA aptamers. RNA, 2008, 14, 1037-1047. (Pubitemid 351717485)
-
(2008)
RNA
, vol.14
, Issue.6
, pp. 1037-1047
-
-
Wurster, S.E.1
Maher III, L.J.2
-
153
-
-
77955125921
-
An RNA aptamer that selectively inhibits the enzymatic activity of protein tyrosine phosphatase 1B in vitro
-
Townshend B.; Aubry I.; Marcellus R.C.; Gehring K.; Tremblay M.L. An RNA aptamer that selectively inhibits the enzymatic activity of protein tyrosine phosphatase 1B in vitro. Chembiochem., 2010, 11, 1583-1593.
-
(2010)
Chembiochem.
, vol.11
, pp. 1583-1593
-
-
Townshend, B.1
Aubry, I.2
Marcellus, R.C.3
Gehring, K.4
Tremblay, M.L.5
-
154
-
-
77954097134
-
Identification of RNA aptamer specific to mutant KRAS protein
-
Jeong S.; Han S.R.; Lee Y.J.; Kim J.H.; Lee S.W. Identification of RNA aptamer specific to mutant KRAS protein. Oligonucleotides, 2010, 20, 155-161.
-
(2010)
Oligonucleotides
, vol.20
, pp. 155-161
-
-
Jeong, S.1
Han, S.R.2
Lee, Y.J.3
Kim, J.H.4
Lee, S.W.5
-
155
-
-
0037264633
-
Targeting RAS signalling pathways in cancer therapy
-
DOI 10.1038/nrc969
-
Downward J. Targeting RAS signalling pathways in cancer therapy. Nat. Rev. Cancer, 2003, 3, 11-22. (Pubitemid 37328883)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.1
, pp. 11-22
-
-
Downward, J.1
-
156
-
-
0032031484
-
Human cancer cell lines growth inhibition by GT(n) oligodeoxyribonucleotides recognizing single-stranded DNA-binding proteins
-
Scaggiante B.; Morassutti C.; Dapas B.; Tolazzi G.; Ustulin F.; Quadrifoglio F. Human cancer cell lines growth inhibition by GTn oligodeoxyribonucleotides recognizing single-stranded DNA-binding proteins. Eur. J. Biochem., 1998, 252, 207-215. (Pubitemid 28101995)
-
(1998)
European Journal of Biochemistry
, vol.252
, Issue.2
, pp. 207-215
-
-
Scaggiante, B.1
Morassutti, C.2
Dapas, B.3
Tolazzi, G.4
Ustulin, F.5
Quadrifoglio, F.6
-
157
-
-
0032780440
-
Effect of oligomer length and base substitutions on the cytotoxic activity and specific nuclear protein recognition of GTn oligonucleotides in the human leukemic CCRF-CEM cell line
-
Morassutti C.; Dapas B.; Scaggiante B.; Paroni G.; Xodo L.; Quadrifoglio F. Effect of oligomer length and base substitutions on the cytotoxic activity and specific nuclear protein recognition of GTn oligonucleotides in the human leukemic CCRF-CEM cell line. Nucleosides Nucleotides, 1999, 18, 1711-1716. (Pubitemid 29362372)
-
(1999)
Nucleosides and Nucleotides
, vol.18
, Issue.6-7
, pp. 1711-1716
-
-
Morassutti, C.1
Dapas, B.2
Scaggiante, B.3
Paroni, G.4
Xodo, L.5
Quadrifoglio, F.6
-
158
-
-
0036696980
-
Increase in therapeutic index of doxorubicin and vinblastine by ap-tameric oligonucleotide in human T lymphoblastic drug-sensitive and multidrug-resistant cells
-
Dapas B.; Perissin L.; Pucillo C.; Quadrifoglio F; Scaggiante B. Increase in therapeutic index of doxorubicin and vinblastine by ap-tameric oligonucleotide in human T lymphoblastic drug-sensitive and multidrug-resistant cells. Antisense Nucleic Acid Drug Dev., 2002, 12, 247-255.
-
(2002)
Antisense Nucleic Acid Drug Dev.
, vol.12
, pp. 247-255
-
-
Dapas, B.1
Perissin, L.2
Pucillo, C.3
Quadrifoglio, F.4
Scaggiante, B.5
-
159
-
-
0042769362
-
Identification of different isoforms of eEF1A in the nuclear fraction of human T-lymphoblastic cancer cell line specifically binding to aptameric cytotoxic GT oligomers
-
DOI 10.1046/j.1432-1033.2003.03713.x
-
Dapas B.; Tell G.; Scaloni A.; Pines A.; Ferrara L.; Quadrifoglio F.; Scaggiante B. Identification of different isoforms of eEF1A in the nuclear fraction of human T-lymphoblastic cancer cell line specifically binding to aptameric cytotoxic GT oligomers. Eur. J. Bio-chem., 2003, 270, 3251-3262. (Pubitemid 36930191)
-
(2003)
European Journal of Biochemistry
, vol.270
, Issue.15
, pp. 3251-3262
-
-
Dapas, B.1
Tell, G.2
Scaloni, A.3
Pines, A.4
Ferrara, L.5
Quadrifoglio, F.6
Scaggiante, B.7
-
160
-
-
23044467818
-
Aptameric GT oligomers need to be complexed to ethoxylated polyethylenimine as pre-paired duplexes to efficiently exert their cytotoxic activity in human lymphoblastic cancer cells
-
DOI 10.1016/j.biochi.2005.03.010, PII S0300908405000829
-
Scaggiante B.; Dapas B.; Perissin L.; Manzini G. Aptameric GT oligomers need to be complexed to ethoxylated polyethylenimine as pre-paired duplexes to efficiently exert their cytotoxic activity in human lymphoblastic cancer cells. Biochimie, 2005, 87, 713-723. (Pubitemid 41058902)
-
(2005)
Biochimie
, vol.87
, Issue.8
, pp. 713-723
-
-
Scaggiante, B.1
Dapas, B.2
Perissin, L.3
Manzini, G.4
-
161
-
-
33745124012
-
Interaction of G-rich GT oligonucleotides with nuclear-associated eEF1A is correlated with their antiproliferative effect in haematopoietic human cancer cell lines
-
DOI 10.1111/j.1742-4658.2006.05143.x
-
Scaggiante B.; Dapas B.; Grassi G.; Manzini G. Interaction of G-rich GT oligonucleotides with nuclear-associated eEF1A is correlated with their antiproliferative effect in haematopoietic human cancer cell lines. FEBS J., 2006, 273, 1350-1361. (Pubitemid 44029102)
-
(2006)
FEBS Journal
, vol.273
, Issue.7
, pp. 1350-1361
-
-
Scaggiante, B.1
Dapas, B.2
Grassi, G.3
Manzini, G.4
-
162
-
-
84855344327
-
Dissecting the expression of EEF1A1/2 genes in human prostate cancer cells: The potential of EEF1A2 as a hallmark for prostate transformation and progression
-
Scaggiante B; Dapas B.; Bonin S.; Grassi M.; Zennaro C.; Farra R.; Cristiano L.; Siracusano S.; Zanconati F.; Giansante C.; Grassi G. Dissecting the expression of EEF1A1/2 genes in human prostate cancer cells: the potential of EEF1A2 as a hallmark for prostate transformation and progression. Br. J. Cancer, 2012, 106, 166-173.
-
(2012)
Br. J. Cancer
, vol.106
, pp. 166-173
-
-
Scaggiante, B.1
Dapas, B.2
Bonin, S.3
Grassi, M.4
Zennaro, C.5
Farra, R.6
Cristiano, L.7
Siracusano, S.8
Zanconati, F.9
Giansante, C.10
Grassi, G.11
|