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Volumn 14, Issue 5, 2013, Pages 565-582

Aptamers as targeting delivery devices or anti-cancer drugs for fighting tumors

Author keywords

Aptamer; Chemical analogues; Drug delivery; EEF1A; Nucleolin; PSMA; SELEX; Tumors

Indexed keywords

ANTINEOPLASTIC AGENT; APTAMER; CISPLATIN; DOXORUBICIN; GELONIN; NUCLEOLIN; PACLITAXEL; SMALL INTERFERING RNA;

EID: 84881630470     PISSN: 13892002     EISSN: 18755453     Source Type: Journal    
DOI: 10.2174/13892002113149990010     Document Type: Article
Times cited : (23)

References (162)
  • 1
    • 0025074907 scopus 로고
    • In vitro selection of RNA molecules that bind specific ligands
    • Ellington, A.D.; Szostak, J.W. In vitro selection of RNA molecules that bind specific ligands. Nature, 1990, 346, 818-22.
    • (1990) Nature , vol.346 , pp. 818-822
    • Ellington, A.D.1    Szostak, J.W.2
  • 2
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
    • Tuerk, C.; Gold, L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science, 1990, 249, 505-10.
    • (1990) Science , vol.249 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 9
    • 46049108242 scopus 로고    scopus 로고
    • Cell-specific internalization study of an aptamer from whole cell selection
    • Xiao, Z.; Shangguan D.; Cao Z.; Fang X.; Tan W. Cell-specific internalization study of an aptamer from whole cell selection. Chemistry, 2008, 14, 1769-75.
    • (2008) Chemistry , vol.14 , pp. 1769-1775
    • Xiao, Z.1    Shangguan, D.2    Cao, Z.3    Fang, X.4    Tan, W.5
  • 10
    • 34249870129 scopus 로고    scopus 로고
    • Aptamers evolved from cultured cancer cells reveal molecular differences of cancer cells in patient samples
    • DOI 10.1373/clinchem.2006.083246
    • Shangguan, D.; Cao, Z.C.; Li, Y.; Tan, W. Aptamers evolved from cultured cancer cells reveal molecular differences of cancer cells in patient samples. Clin. Chem., 2007, 53, 1153-1155. (Pubitemid 46867534)
    • (2007) Clinical Chemistry , vol.53 , Issue.6 , pp. 1153-1155
    • Shangguan, D.1    Cao, Z.C.2    Li, Y.3    Tan, W.4
  • 12
    • 33749512390 scopus 로고    scopus 로고
    • A new technique for the isolation and surface immobilization of mesenchymal stem cells from whole bone marrow using high-specific DNA aptamers
    • DOI 10.1634/stemcells.2006-0015
    • Guo, K.T.; SchAfer, R.; Paul, A.; Gerber, A.; Ziemer, G.; Wendel, H.P. A new technique for the isolation and surface immobilization of mesenchymal stem cells from whole bone marrow using high-specific DNA aptamers. Stem Cells, 2006, 24, 2220-2231. (Pubitemid 44527475)
    • (2006) Stem Cells , vol.24 , Issue.10 , pp. 2220-2231
    • Guo, K.-T.1    Schafer, R.2    Paul, A.3    Gerber, A.4    Ziemer, G.5    Wendel, H.P.6
  • 13
    • 39049142223 scopus 로고    scopus 로고
    • Pegaptanib sodium for the treatment of age-related macular degeneration
    • DOI 10.1517/14656566.9.3.499
    • Apte R.S. Pegaptanib sodium for the treatment of age-related macular degeneration. Expert Opin. Pharmacother., 2008, 9, 499-508. (Pubitemid 351291794)
    • (2008) Expert Opinion on Pharmacotherapy , vol.9 , Issue.3 , pp. 499-508
    • Apte, R.S.1
  • 16
    • 0033428608 scopus 로고    scopus 로고
    • Effect of phosphorothioate modifications on the ability of GTn oligodeoxynucleotides to specifically recognize single-stranded DNA-binding proteins and to affect human cancer cellular growth
    • DOI 10.1016/S0300-9084(99)00350-8
    • Morassutti, C.; Scaggiante, B.; Dapas, B.; Xodo, L.; Tell, G.; Quadrifoglio, F. Effect of phosphorothioate modifications on the ability of GTn oligodeoxynucleotides to specifically recognize single-stranded DNA-binding proteins and to affect human cancer cellular growth. Biochimie, 1999, 81, 1115-1122. (Pubitemid 30006551)
    • (1999) Biochimie , vol.81 , Issue.12 , pp. 1115-1122
    • Morassutti, C.1    Scaggiante, B.2    Dapas, B.3    Xodo, L.4    Tell, G.5    Quadrifoglio, F.6
  • 17
    • 0035695234 scopus 로고    scopus 로고
    • Alpha-anomeric configuration of GT oligodeoxynucleotide leads to loss of the specific aptameric and cytotoxic properties retained by the beta-anomeric analog
    • Scaggiante, B.; Dapas, B.; Quadrifoglio, F. Alpha-anomeric configuration of GT oligodeoxynucleotide leads to loss of the specific aptameric and cytotoxic properties retained by the beta-anomeric analog. Antisense Nucleic Acid Drug Dev., 2001, 11, 395-399. (Pubitemid 34106805)
    • (2001) Antisense and Nucleic Acid Drug Development , vol.11 , Issue.6 , pp. 395-399
    • Scaggiante, B.1    Dapas, B.2    Quadrifoglio, F.3
  • 18
    • 70349786346 scopus 로고    scopus 로고
    • The chemical biology of aptamers
    • Mayer, G. The chemical biology of aptamers. Angew Chem. Int. E., Engl., 2009, 48, 2672-2689.
    • (2009) Angew Chem. Int. E., Engl. , vol.48 , pp. 2672-2689
    • Mayer, G.1
  • 21
    • 46049121018 scopus 로고    scopus 로고
    • Polymerase chain reaction and transcription using locked nucleic acid nucleotide triphosphates
    • DOI 10.1021/ja801389n
    • Veedu, R.N.; Vester, B.; Wengel, J. Polymerase chain reaction and transcription using locked nucleic acid nucleotide triphosphates. J. Am. Chem Soc, 2008, 130, 8124-8125. (Pubitemid 351898512)
    • (2008) Journal of the American Chemical Society , vol.130 , Issue.26 , pp. 8124-8125
    • Veedu, R.N.1    Vester, B.2    Wengel, J.3
  • 23
    • 81455144711 scopus 로고    scopus 로고
    • Locked vs. Unlocked nucleic acids [LNA vs. UNA]: Contrasting structures work towards common therapeutic goals
    • Campbell, M.A.; Wengel, J. Locked vs. unlocked nucleic acids [LNA vs. UNA]: contrasting structures work towards common therapeutic goals. Chem. Soc. Rev., 2011, 40(12), 5680-9.
    • (2011) Chem. Soc. Rev. , vol.40 , Issue.12 , pp. 5680-5689
    • Campbell, M.A.1    Wengel, J.2
  • 24
    • 0032493654 scopus 로고    scopus 로고
    • 165): Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain
    • DOI 10.1074/jbc.273.32.20556
    • Ruckman, J.; Green, L.S.; Beeson, J.; Waugh, S.; Gillette, W.L.; Henninger, D.D.; Claesson-Welsh, L.; Janjic, N. 2'-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor [VEGF165]. Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain. J. Biol. Chem., 1998, 273, 20556-20567. (Pubitemid 28377626)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.32 , pp. 20556-20567
    • Ruckman, J.1    Green, L.S.2    Beeson, J.3    Waugh, S.4    Gillette, W.L.5    Henninger, D.D.6    Claesson-Welsh, L.7    Janjic, N.8
  • 26
    • 80052230213 scopus 로고    scopus 로고
    • Improving the stability of aptamers by chemical modification
    • Wang, R.E.; Wu, H.; Niu, Y.; Cai, J. Improving the stability of aptamers by chemical modification. Curr. Med. Chem., 2011, 8, 4126-4138.
    • (2011) Curr. Med. Chem. , vol.8 , pp. 4126-4138
    • Wang, R.E.1    Wu, H.2    Niu, Y.3    Cai, J.4
  • 28
    • 32544435129 scopus 로고    scopus 로고
    • Pharmacologic and pharmacokinetic assessment of anti-TGFβ2 aptamers in rabbit plasma and aqueous humor
    • DOI 10.1007/s11095-005-9305-2
    • McCauley, T.G.; Kurz, J.C.; Merlino, P.G.; Lewis, S.D.; Gilbert, M.; Epstein, D.M.; Marsh, H.N. Pharmacologic and pharmacokinetic assessment of anti-TGFbeta2 aptamers in rabbit plasma and aqueous humor. Pharm. Res., 2006, 23, 303-311. (Pubitemid 43237861)
    • (2006) Pharmaceutical Research , vol.23 , Issue.2 , pp. 303-311
    • McCauley, T.G.1    Kurz, J.C.2    Merlino, P.G.3    Lewis, S.D.4    Gilbert, M.5    Epstein, D.M.6    Marsh, H.N.7
  • 29
    • 0142043453 scopus 로고    scopus 로고
    • Spiegelmers: Biostable aptamers
    • DOI 10.1002/cbic.200300663
    • Eulberg, D.; Klussmann, S. Spiegelmers: biostable aptamers. Chembiochem., 2003, 4 (10), 979-983. (Pubitemid 37267585)
    • (2003) ChemBioChem , vol.4 , Issue.10 , pp. 979-983
    • Eulberg, D.1    Klussmann, S.2
  • 32
    • 78650072690 scopus 로고    scopus 로고
    • Polyetheylenimine-polyplexes of spiegelmer NOX-A50 directed against intracellular high mobility group protein A1 [HMGA1] reduce tumor growth in vivo
    • Maasch C; Vater A.; Buchner K.; Purschke W.G.; Eulberg D.; Vonhoff S.; Klussmann S. Polyetheylenimine-polyplexes of Spiegelmer NOX-A50 directed against intracellular high mobility group protein A1 [HMGA1] reduce tumor growth in vivo. J. Biol. Chem., 2010, 285, 40012-40018.
    • (2010) J. Biol. Chem. , vol.285 , pp. 40012-40018
    • Maasch, C.1    Vater, A.2    Buchner, K.3    Purschke, W.G.4    Eulberg, D.5    Vonhoff, S.6    Klussmann, S.7
  • 34
    • 74049099526 scopus 로고    scopus 로고
    • The therapeutic potential of cell-internalizing aptamers
    • Zhou J.; Rossi JJ. The therapeutic potential of cell-internalizing aptamers. Curr. Top. Med. Chem., 2009, 9, 1144-1157.
    • (2009) Curr. Top. Med. Chem. , vol.9 , pp. 1144-1157
    • Zhou, J.1    Rossi, J.J.2
  • 35
    • 76249127542 scopus 로고    scopus 로고
    • DNA aptamer-micelle as an efficient detection/delivery vehicle toward cancer cells
    • Wu Y.; Sefah K.; Liu H. Wang R.; Tan W. DNA aptamer-micelle as an efficient detection/delivery vehicle toward cancer cells. Proc. Natl. Acad. Sci. U. S. A., 2010, 107, 5-10.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 5-10
    • Wu, Y.1    Sefah, K.2    Liu, H.3    Wang, R.4    Tan, W.5
  • 36
    • 78650362849 scopus 로고    scopus 로고
    • Intracellular traffic of oligodeoxynucleotides in and out of the nucleus: Effect of exportins and DNA structure
    • Forsha S.J.; Panyutin I.V.; Neumann R.D.; Panyutin I.G. Intracellular traffic of oligodeoxynucleotides in and out of the nucleus: effect of exportins and DNA structure. Oligonucleotides, 2010, 20, 277-284.
    • (2010) Oligonucleotides , vol.20 , pp. 277-284
    • Forsha, S.J.1    Panyutin, I.V.2    Neumann, R.D.3    Panyutin, I.G.4
  • 37
    • 79551561775 scopus 로고    scopus 로고
    • Reversible targeting and controlled release delivery of daunorubicin to cancer cells by aptamer-wrapped carbon nanotubes
    • Taghdisi S.M.; Lavaee P.; Ramezani M.; Abnous K. Reversible targeting and controlled release delivery of daunorubicin to cancer cells by aptamer-wrapped carbon nanotubes. Eur. J. Pharm. Bio-pharm., 2011, 77, 200-206.
    • (2011) Eur. J. Pharm. Bio-pharm. , vol.77 , pp. 200-206
    • Taghdisi, S.M.1    Lavaee, P.2    Ramezani, M.3    Abnous, K.4
  • 38
    • 33746172167 scopus 로고    scopus 로고
    • Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models
    • DOI 10.1158/0008-5472.CAN-05-4199
    • Kirpotin D.B.; Drummond D.C.; Shao Y.; Shalaby M.R.; Hong K.; Nielsen U.B.; Marks J.D.; Benz CC; Park J.W. Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models. Cancer Res., 2006, 66, 6732-6740. (Pubitemid 44085631)
    • (2006) Cancer Research , vol.66 , Issue.13 , pp. 6732-6740
    • Kirpotin, D.B.1    Drummond, D.C.2    Shao, Y.3    Shalaby, M.R.4    Hong, K.5    Nielsen, U.B.6    Marks, J.D.7    Benz, C.C.8    Park, J.W.9
  • 39
    • 0033790673 scopus 로고    scopus 로고
    • Escort aptamers: A delivery service for diagnosis and therapy
    • Hicke B.J.; Stephens A.W. Escort aptamers: a delivery service for diagnosis and therapy. J Clin Invest., 2000, 106, 923-928.
    • (2000) J Clin Invest. , vol.106 , pp. 923-928
    • Hicke, B.J.1    Stephens, A.W.2
  • 40
    • 33845723241 scopus 로고    scopus 로고
    • An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform
    • DOI 10.1002/anie.200602251
    • Bagalkot V.; Farokhzad O.C; Langer R.; Jon S. An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform. Angew Chem. Int. Ed. Engl, 2006, 45, 8149-8152. (Pubitemid 44974149)
    • (2006) Angewandte Chemie - International Edition , vol.45 , Issue.48 , pp. 8149-8152
    • Bagalkot, V.1    Farokhzad, O.C.2    Langer, R.3    Jon, S.4
  • 42
    • 56249097260 scopus 로고    scopus 로고
    • Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized pt [IV] prodrug-PLGA-PEG nanoparticles
    • Dhar S.; Gu F.X.; Langer R.; Farokhzad O.C.; Lippard S.J. Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt [IV] prodrug-PLGA-PEG nanoparticles. Proc. Natl. Acad. Sci. U. S. A., 2008, 105, 17356-17361.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 17356-17361
    • Dhar, S.1    Gu, F.X.2    Langer, R.3    Farokhzad, O.C.4    Lippard, S.J.5
  • 48
    • 0037099536 scopus 로고    scopus 로고
    • Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen
    • Lupold S.E.; Hicke B.J.; Lin Y.; Coffey D.S. Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen. Cancer Res., 2002, 62, 4029-4033. (Pubitemid 34791070)
    • (2002) Cancer Research , vol.62 , Issue.14 , pp. 4029-4033
    • Lupold, S.E.1    Hicke, B.J.2    Lin, Y.3    Coffey, D.S.4
  • 53
    • 55449127119 scopus 로고    scopus 로고
    • Cell-specific induction of apoptosis by rationally designed bivalent ap-tamer-siRNA transcripts silencing Eukaryotic elongation factor 2
    • Wullner U.; Neef I.; Eller A.; Kleines M.; Tur M.K.; Barth S. Cell-specific induction of apoptosis by rationally designed bivalent ap-tamer-siRNA transcripts silencing eukaryotic elongation factor 2. Curr. Cancer Drug Target., 2008, 8, 554-565.
    • (2008) Curr. Cancer Drug Target. , vol.8 , pp. 554-565
    • Wullner, U.1    Neef, I.2    Eller, A.3    Kleines, M.4    Tur, M.K.5    Barth, S.6
  • 54
    • 77950051368 scopus 로고    scopus 로고
    • Prostate cancer cell death produced by the co-delivery of bcl-xL shRNA and doxorubicin using an aptamer-conjugated polyplex
    • Kim E.; Jung Y.; Choi H.; Yang J.; Suh J.S.; Huh Y.M.; Kim K.; Haam S. Prostate cancer cell death produced by the co-delivery of Bcl-xL shRNA and doxorubicin using an aptamer-conjugated polyplex. Biomaterials, 2010, 31, 4592-4599.
    • (2010) Biomaterials , vol.31 , pp. 4592-4599
    • Kim, E.1    Jung, Y.2    Choi, H.3    Yang, J.4    Suh, J.S.5    Huh, Y.M.6    Kim, K.7    Haam, S.8
  • 55
    • 76749138904 scopus 로고    scopus 로고
    • The formulation of aptamer-coated paclitaxel-polylactide nanoconjugates and their targeting to cancer cells
    • Tong R.; Yala L.; Fan T.M.; Cheng J. The formulation of aptamer-coated paclitaxel-polylactide nanoconjugates and their targeting to cancer cells. Biomaterials, 2010, 31, 3043-3053.
    • (2010) Biomaterials , vol.31 , pp. 3043-3053
    • Tong, R.1    Yala, L.2    Fan, T.M.3    Cheng, J.4
  • 56
    • 79952165883 scopus 로고    scopus 로고
    • Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo
    • Dhar S.; Kolishetti N.; Lippard S.J.; Farokhzad O.C. Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo. Proc. Natl. Acad. Sci. U. S. A., 2011, 108, 1850-1855.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 1850-1855
    • Dhar, S.1    Kolishetti, N.2    Lippard, S.J.3    Farokhzad, O.C.4
  • 57
    • 80054681184 scopus 로고    scopus 로고
    • Targeted chemoimmunotherapy using drug-loaded aptamer-dendrimer bio-conjugates
    • May 27, in press
    • Lee I.H.; An S.; Yu M.K.; Kwon H.K.; Im S.H.; Jon S. Targeted chemoimmunotherapy using drug-loaded aptamer-dendrimer bio-conjugates. J. Control. Release, 2011, May 27, in press.
    • (2011) J. Control. Release
    • Lee, I.H.1    An, S.2    Yu, M.K.3    Kwon, H.K.4    Im, S.H.5    Jon, S.6
  • 59
    • 78651419151 scopus 로고    scopus 로고
    • Dual-aptamer-based delivery vehicle of doxorubicin to both PSMA [+]and PSMA [-] prostate cancers
    • Min K.; Jo H.; Song K.; Cho M.; Chun Y.S.; Jon S.; Kim W.J.; Ban C. Dual-aptamer-based delivery vehicle of doxorubicin to both PSMA [+]and PSMA [-] prostate cancers. Biomaterials, 2011, 32, 2124-2132.
    • (2011) Biomaterials , vol.32 , pp. 2124-2132
    • Min, K.1    Jo, H.2    Song, K.3    Cho, M.4    Chun, Y.S.5    Jon, S.6    Kim, W.J.7    Ban, C.8
  • 60
    • 0032837376 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay in health and disease
    • DOI 10.1093/hmg/8.10.1893
    • Frischmeyer P.A.; Dietz H.C. Nonsense-mediated mRNA decay in health and disease. Hum. Mol. Genet., 1999, 8, 1893-1900. (Pubitemid 29458667)
    • (1999) Human Molecular Genetics , vol.8 , Issue.10 , pp. 1893-1900
    • Frischmeyer, P.A.1    Dietz, H.C.2
  • 61
    • 77952380547 scopus 로고    scopus 로고
    • Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay
    • Pastor F.; Kolonias D.; Giangrande P.H.; Gilboa E. Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay. Nature, 2010, 465, 227-230.
    • (2010) Nature , vol.465 , pp. 227-230
    • Pastor, F.1    Kolonias, D.2    Giangrande, P.H.3    Gilboa, E.4
  • 63
    • 80053576818 scopus 로고    scopus 로고
    • Targeting 4-1BB costimulation to disseminated tumor lesions with bi-specific oligonucleotide aptamers
    • Pastor F.; Kolonias D.; McNamara J.O.; Gilboa E. Targeting 4-1BB costimulation to disseminated tumor lesions with bi-specific oligonucleotide aptamers. Mol. Ther., 2011, 19, 1878-1886.
    • (2011) Mol. Ther. , vol.19 , pp. 1878-1886
    • Pastor, F.1    Kolonias, D.2    McNamara, J.O.3    Gilboa, E.4
  • 66
    • 0347123435 scopus 로고    scopus 로고
    • Mucins in cancer: Protection and control of the cell surface
    • Hollingsworth M.A.; Swanson B.J. Mucins in cancer: protection and control of the cell surface. Nat. Rev. Cancer, 2004, 4, 45-60. (Pubitemid 38082153)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.1 , pp. 45-60
    • Hollingsworth, M.A.1    Swanson, B.J.2
  • 67
    • 0030829346 scopus 로고    scopus 로고
    • Comparison of MUC-1 mucin expression in epithelial and non-epithelial cancer cell lines and demonstration of a new short variant form (MUC-1/Z)
    • DOI 10.1002/(SICI)1097-0215(19970703)72:1<87::AID-IJC13>3.0.CO;2-7
    • Oosterkamp H.M.; Scheiner L.; Stefanova M.C.; Lloyd K.O.; Finstad C.L. Comparison of MUC-1 mucin expression in epithelial and non-epithelial cancer cell lines and demonstration of a new short variant form [MUC-1/Z]. Int. J. Cancer, 1997, 72, 87-94. (Pubitemid 27314644)
    • (1997) International Journal of Cancer , vol.72 , Issue.1 , pp. 87-94
    • Oosterkamp, H.M.1    Scheiner, L.2    Stefanova, M.C.3    Lloyd, K.O.4    Finstad, C.L.5
  • 68
    • 0035884392 scopus 로고    scopus 로고
    • The epithelial tumor antigen MUC1 is expressed in hematological malignancies and is recognized by MUC1-specific cytotoxic T-lymphocytes
    • Brossart P.; Schneider A.; Dill P.; Schammann T.; Grünebach F.; Wirths S.; Kanz L.; Bühring H.J.; Brugger W. The epithelial tumor antigen MUC1 is expressed in hematological malignancies and is recognized by MUC1-specific cytotoxic T-lymphocytes. Cancer Res., 2001, 61, 6846-6850. (Pubitemid 32896509)
    • (2001) Cancer Research , vol.61 , Issue.18 , pp. 6846-6850
    • Brossart, P.1    Schneider, A.2    Dill, P.3    Schammann, T.4    Grunebach, F.5    Wirths, S.6    Kanz, L.7    Buhring, H.-J.8    Brugger, W.9
  • 69
    • 33750445311 scopus 로고    scopus 로고
    • DNA aptamers that bind to MUC1 tumour marker: Design and characterization of MUC1-binding single-stranded DNA aptamers
    • DOI 10.1159/000096085
    • Ferreira C.S.M.; Matthews C.S.; Missailidis S. DNA Aptamers That Bind to MUC1 Tumour Marker: Design and Characterization of MUC1-Binding Single-Stranded DNA Aptamers. Tumor Biol., 2006, 27, 289-301. (Pubitemid 44646223)
    • (2006) Tumor Biology , vol.27 , Issue.6 , pp. 289-301
    • Ferreira, C.S.M.1    Matthews, C.S.2    Missailidis, S.3
  • 71
    • 38849205404 scopus 로고    scopus 로고
    • DNA aptamers against the MUC1 tumour marker: Design of aptamer-antibody sandwich ELISA for the early diagnosis of epithelial tumours
    • DOI 10.1007/s00216-007-1470-1, Aptamers and their applications
    • Ferreira C.S.; Papamichael K.; Guilbault G.; Schwarzacher T.; Gariepy J.; Missailidis S. DNA aptamers against the MUC1 tumour marker: design of aptamer-antibody sandwich ELISA for the early diagnosis of epithelial tumours. Anal Bioanal Chem., 2008, 390, 1039-1050. (Pubitemid 351207802)
    • (2008) Analytical and Bioanalytical Chemistry , vol.390 , Issue.4 , pp. 1039-1050
    • Ferreira, C.S.M.1    Papamichael, K.2    Guilbault, G.3    Schwarzacher, T.4    Gariepy, J.5    Missailidis, S.6
  • 72
    • 67651162036 scopus 로고    scopus 로고
    • Anti-MUC1 aptamers: Radiolabelling with [99m]Tc and biodistribution in MCF-7 tumour-bearing mice
    • Pieve C.D.; Perkins A.C.; Missailidis S. Anti-MUC1 aptamers: radiolabelling with [99m]Tc and biodistribution in MCF-7 tumour-bearing mice. Nucl. Med. Biol., 2009, 36, 703-710.
    • (2009) Nucl. Med. Biol. , vol.36 , pp. 703-710
    • Pieve, C.D.1    Perkins, A.C.2    Missailidis, S.3
  • 73
    • 80053903275 scopus 로고    scopus 로고
    • PEGylated anti-MUC1 aptamer-doxorubicin complex for targeted drug delivery to MCF7 breast cancer cells
    • Tan L.; Neoh K.G.; Kang E.T.; Choe W.S.; Su X. PEGylated anti-MUC1 aptamer-doxorubicin complex for targeted drug delivery to MCF7 breast cancer cells. Macromol. Biosci., 2011, 11, 1331-1335.
    • (2011) Macromol. Biosci. , vol.11 , pp. 1331-1335
    • Tan, L.1    Neoh, K.G.2    Kang, E.T.3    Choe, W.S.4    Su, X.5
  • 75
    • 77949268954 scopus 로고    scopus 로고
    • Aptamer-biotin-streptavidin-C1q complexes can trigger the classical complement pathway to kill cancer cells
    • In Vitro
    • Bruno J.G. Aptamer-biotin-streptavidin-C1q complexes can trigger the classical complement pathway to kill cancer cells. In Vitro Cell Dev. Biol. Anim., 2010, 46, 107-113.
    • (2010) Cell Dev. Biol. Anim. , vol.46 , pp. 107-113
    • Bruno, J.G.1
  • 76
    • 67651003100 scopus 로고    scopus 로고
    • The emerging role of EpCAM in cancer and stem cell signaling
    • Munz M.; Baeuerle P.A.; Gires O. The emerging role of EpCAM in cancer and stem cell signaling. Cancer Res., 2009, 69, 5627-5629.
    • (2009) Cancer Res. , vol.69 , pp. 5627-5629
    • Munz, M.1    Baeuerle, P.A.2    Gires, O.3
  • 78
    • 78650991636 scopus 로고    scopus 로고
    • Phase II study of the human anti-epithelial cell adhesion molecule antibody adecatumumab in prostate cancer patients with increasing serum levels of prostate-specific antigen after radical prostatectomy
    • Marschner N.; Rüttinger D.; Zugmaier G.; Nemere G.; Lehmann J.; Obrist P.; Baeuerle P.A.; Wolf A.; Schmidt M.; Abrahamsson P.A.; Reinhardt C.; Heidenreich A. Phase II study of the human anti-epithelial cell adhesion molecule antibody adecatumumab in prostate cancer patients with increasing serum levels of prostate-specific antigen after radical prostatectomy. Urol. Int., 2010, 85, 386-395.
    • (2010) Urol. Int. , vol.85 , pp. 386-395
    • Marschner, N.1    Rüttinger, D.2    Zugmaier, G.3    Nemere, G.4    Lehmann, J.5    Obrist, P.6    Baeuerle, P.A.7    Wolf, A.8    Schmidt, M.9    Abrahamsson, P.A.10    Reinhardt, C.11    Heidenreich, A.12
  • 79
    • 79954858874 scopus 로고    scopus 로고
    • RNA aptamer against a cancer stem cell marker epithelial cell adhesion molecule
    • Shigdar S.; Lin J.; Yu Y.; Pastuovic M.; Wei M.; Duan W. RNA aptamer against a cancer stem cell marker epithelial cell adhesion molecule. Cancer Sci., 2011, 102, 991-998.
    • (2011) Cancer Sci. , vol.102 , pp. 991-998
    • Shigdar, S.1    Lin, J.2    Yu, Y.3    Pastuovic, M.4    Wei, M.5    Duan, W.6
  • 82
    • 11344278689 scopus 로고    scopus 로고
    • RNA aptamers selected against the receptor activator of NF-αB acquire general affinity to proteins of the tumor necrosis factor receptor family
    • DOI 10.1093/nar/gkh949
    • Mori T.; Oguro A.; Ohtsu T.; Nakamura Y. RNA aptamers selected against the receptor activator of NF-kappaB acquire general affinity to proteins of the tumor necrosis factor receptor family. Nucleic Acids Res., 2004, 32, 6120-6128. (Pubitemid 40074006)
    • (2004) Nucleic Acids Research , vol.32 , Issue.20 , pp. 6120-6128
    • Mori, T.1    Oguro, A.2    Ohtsu, T.3    Nakamura, Y.4
  • 83
    • 70549112254 scopus 로고    scopus 로고
    • Using an RNA aptamer probe for flow cytometry detection of CD30-expressing lymphoma cells
    • Zhang P.; Zhao N.; Zeng Z.; Feng Y.; Tung C.H.; Chang C.C.; Zu Y. Using an RNA aptamer probe for flow cytometry detection of CD30-expressing lymphoma cells. Lab Invest., 2009, 89, 1423-1432.
    • (2009) Lab Invest. , vol.89 , pp. 1423-1432
    • Zhang, P.1    Zhao, N.2    Zeng, Z.3    Feng, Y.4    Tung, C.H.5    Chang, C.C.6    Zu, Y.7
  • 84
    • 34347396141 scopus 로고    scopus 로고
    • Downregulation of NPM-ALK by siRNA causes anaplastic large cell lymphoma cell growth inhibition and augments the anti cancer effects of chemotherapy in vitro
    • DOI 10.1080/07357900701206372, PII 779831627
    • Hsu F.Y.; Zhao Y.; Anderson W.F.; Johnston P.B. Downregulation of NPM-ALK by siRNA causes anaplastic large cell lymphoma cell growth inhibition and augments the anti cancer effects of chemotherapy in vitro. Cancer Invest, 2007, 25, 240-248. (Pubitemid 47026946)
    • (2007) Cancer Investigation , vol.25 , Issue.4 , pp. 240-248
    • Hsu, F.Y.-Y.1    Zhao, Y.2    Anderson, W.F.3    Johnston, P.B.4
  • 85
    • 79251568958 scopus 로고    scopus 로고
    • A nanocomplex that is both tumor cell-selective and cancer gene-specific for anaplastic large cell lymphoma
    • Zhao N.; Bagaria H.G.; Wong M.S.; Zu Y. A nanocomplex that is both tumor cell-selective and cancer gene-specific for anaplastic large cell lymphoma. J. Nanobiotechnol, 2011, 9, 2-12.
    • (2011) J. Nanobiotechnol , vol.9 , pp. 2-12
    • Zhao, N.1    Bagaria, H.G.2    Wong, M.S.3    Zu, Y.4
  • 86
    • 1642446081 scopus 로고    scopus 로고
    • Expert Review of Non-Hodgkin's Lymphomas in a Population-Based Cancer Registry: Reliability of Diagnosis and Subtype Classifications
    • DOI 10.1158/1055-9965.EPI-03-0250
    • Clarke CA.; Glaser S.L.; Dorfman R.F.; Bracci P.M.; Eberle E.; Holly E.A. Expert review of non-Hodgkin's lymphomas in a population-based cancer registry: reliability of diagnosis and subtype classifications. Cancer Epidemiol. Biomarkers Prev., 2004, 13, 138-143. (Pubitemid 38116631)
    • (2004) Cancer Epidemiology Biomarkers and Prevention , vol.13 , Issue.1 , pp. 138-143
    • Clarke, C.A.1    Glaser, S.L.2    Dorfman, R.F.3    Bracci, P.M.4    Eberle, E.5    Holly, E.A.6
  • 87
    • 38349061033 scopus 로고    scopus 로고
    • Aptamer directly evolved from live cells recognizes membrane bound immunoglobin heavy mu chain in Burkitt's lymphoma cells
    • Mallikaratchy P.; Tang Z.; Kwame S.; Meng L.; Shangguan D.; Tan W. Aptamer directly evolved from live cells recognizes membrane bound immunoglobin heavy mu chain in Burkitt's lymphoma cells. Mol. Cell Proteomics, 2007, 6, 2230-2238.
    • (2007) Mol. Cell Proteomics , vol.6 , pp. 2230-2238
    • Mallikaratchy, P.1    Tang, Z.2    Kwame, S.3    Meng, L.4    Shangguan, D.5    Tan, W.6
  • 89
    • 65549102827 scopus 로고    scopus 로고
    • Molecular assembly of an aptamer-drug conjugate for targeted drug delivery to tumor cells
    • Huang Y.F.; Shangguan D.; Liu H.; Phillips J.A.; Zhang X.; Chen Y.; Tan W. Molecular assembly of an aptamer-drug conjugate for targeted drug delivery to tumor cells. Chembiochem., 2009, 10, 862-868.
    • (2009) Chembiochem. , vol.10 , pp. 862-868
    • Huang, Y.F.1    Shangguan, D.2    Liu, H.3    Phillips, J.A.4    Zhang, X.5    Chen, Y.6    Tan, W.7
  • 91
    • 14644422666 scopus 로고    scopus 로고
    • Potential oncogenic action of tenascin-C in tumorigenesis
    • DOI 10.1016/j.biocel.2004.12.002
    • Orend G. Potential oncogenic action of tenascin-C in tumorigene-sis. Int. J. Biochem. Cell Biol, 2005, 37, 1066-1083. (Pubitemid 40311747)
    • (2005) International Journal of Biochemistry and Cell Biology , vol.37 , pp. 1066-1083
    • Orend, G.1
  • 92
    • 33749452709 scopus 로고    scopus 로고
    • Tenascin-C induced signaling in cancer
    • DOI 10.1016/j.canlet.2006.02.017, PII S0304383506001418
    • Orend G.; Chiquet-Ehrismann R. Tenascin-C induced signaling in cancer. Cancer Lett, 2006, 244, 143-163. (Pubitemid 44508708)
    • (2006) Cancer Letters , vol.244 , Issue.2 , pp. 143-163
    • Orend, G.1    Chiquet-Ehrismann, R.2
  • 95
    • 84881631306 scopus 로고    scopus 로고
    • 99mTc-Mercaptoacetyl-Glu-Glu-aptamer specific for tenascin-C. Molecular imaging and contrast agent database [MI-CAD] [Internet]
    • Jul 17 [updated 2008 Aug 12]
    • 99mTc-Mercaptoacetyl-Glu-Glu-aptamer specific for tenascin-C. Molecular Imaging and Contrast Agent Database [MI-CAD] [Internet]. Bethesda [MD]: National Center for Biotechnology Information [US]; 2004-2010. 2008 Jul 17 [updated 2008 Aug 12].
    • (2008) Bethesda [MD]: National Center for Biotechnology Information [US]; 2004-2010
    • Zhang, H.1
  • 96
    • 77956926324 scopus 로고    scopus 로고
    • Polylactide nanoparticles containing stably incorporated cyanine dyes for in vitro and in vivo imaging applications
    • Tong R.; Coyle V.J.; Tang L.; Barger A.M.; Fan T.M.; Cheng J. Polylactide nanoparticles containing stably incorporated cyanine dyes for in vitro and in vivo imaging applications. Microsc. Res. Tech., 2010, 73, 901-909.
    • (2010) Microsc. Res. Tech. , vol.73 , pp. 901-909
    • Tong, R.1    Coyle, V.J.2    Tang, L.3    Barger, A.M.4    Fan, T.M.5    Cheng, J.6
  • 98
    • 79960078032 scopus 로고    scopus 로고
    • Tumor targeted quantum dot-mucin 1 aptamer-doxorubicin conjugate for imaging and treatment of cancer
    • Savla R.; Taratula O.; Garbuzenko O.; Minko T. Tumor targeted quantum dot-mucin 1 aptamer-doxorubicin conjugate for imaging and treatment of cancer. J Control. Release, 2011, 153(1), 16-22.
    • (2011) J Control. Release , vol.153 , Issue.1 , pp. 16-22
    • Savla, R.1    Taratula, O.2    Garbuzenko, O.3    Minko, T.4
  • 100
    • 33846252731 scopus 로고    scopus 로고
    • Discovery and development of anticancer aptamers
    • DOI 10.1158/1535-7163.MCT-06-0172
    • Ireson CR.; Kelland L.R. Discovery and development of anticancer aptamers. Mol. Cancer Ther., 2006, 5, 2957-2962. (Pubitemid 46092036)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.12 , pp. 2957-2962
    • Ireson, C.R.1    Kelland, L.R.2
  • 101
    • 0033543548 scopus 로고    scopus 로고
    • Antiproliferative activity of G-rich oligonucleotides correlates with protein binding
    • Bates P.J.; Kahlon J.B.; Thomas S.D.; Trent J.O.; Miller D.M. Antiproliferative activity of G-rich oligonucleotides correlates with protein binding. J. Biol. Chem., 1999, 274, 26369-26377.
    • (1999) J. Biol. Chem. , vol.274 , pp. 26369-26377
    • Bates, P.J.1    Kahlon, J.B.2    Thomas, S.D.3    Trent, J.O.4    Miller, D.M.5
  • 102
    • 0037133510 scopus 로고    scopus 로고
    • Antiproliferative activity of G-quartet-forming oligonucleotides with backbone and sugar modifications
    • DOI 10.1021/bi0119520
    • Dapic V; Bates PJ; Trent JO; Rodger A; Thomas SD; Miller DM. Antiproliferative activity of G-quartet-forming oligonucleotides with backbone and sugar modifications. Biochemistry, 2002, 41, 3676-85. (Pubitemid 34224680)
    • (2002) Biochemistry , vol.41 , Issue.11 , pp. 3676-3685
    • Dapic, V.1    Bates, P.J.2    Trent, J.O.3    Rodger, A.4    Thomas, S.D.5    Miller, D.M.6
  • 103
    • 42049124068 scopus 로고    scopus 로고
    • The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells
    • DOI 10.1158/0008-5472.CAN-07-5723
    • Soundararajan S.; Chen W.; Spicer E.K.; Courtenay-Luck N.; Fernandes D.J. The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells. Cancer Res., 2008, 68, 2358-2365. (Pubitemid 351521810)
    • (2008) Cancer Research , vol.68 , Issue.7 , pp. 2358-2365
    • Soundararajan, S.1    Chen, W.2    Spicer, E.K.3    Courtenay-Luck, N.4    Fernandes, D.J.5
  • 104
    • 76749169748 scopus 로고    scopus 로고
    • AS-1411; a guanosine-rich oligonucleo-tide aptamer targeting nucleolin for the potential treatment of cancer; including acute myeloid Leukemia
    • Mongelard F.; Bouvet P. AS-1411; a guanosine-rich oligonucleo-tide aptamer targeting nucleolin for the potential treatment of cancer; including acute myeloid leukemia. Curr. Opin. Mol. Ther., 2010, 12, 107-114.
    • (2010) Curr. Opin. Mol. Ther. , vol.12 , pp. 107-114
    • Mongelard, F.1    Bouvet, P.2
  • 105
    • 34249777555 scopus 로고    scopus 로고
    • Functions of the histone chaperone nucleolin in diseases
    • Storck S.; Shukla M.; Dimitrov S.; Bouvet P. Functions of the histone chaperone nucleolin in diseases. Subcell Biochem., 2007, 41, 125-144.
    • (2007) Subcell Biochem. , vol.41 , pp. 125-144
    • Storck, S.1    Shukla, M.2    Dimitrov, S.3    Bouvet, P.4
  • 108
    • 67349167635 scopus 로고    scopus 로고
    • Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer
    • Bates P.J.; Laber D.A.; Miller D.M.; Thomas S.D.; Trent J.O. Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer. Exp. Mol. Pathol., 2009, 86, 151-164.
    • (2009) Exp. Mol. Pathol. , vol.86 , pp. 151-164
    • Bates, P.J.1    Laber, D.A.2    Miller, D.M.3    Thomas, S.D.4    Trent, J.O.5
  • 110
    • 35948945681 scopus 로고    scopus 로고
    • AS1411 alters the localization of a complex containing protein arginine methyltransferase 5 and nucleolin
    • DOI 10.1158/0008-5472.CAN-06-4206
    • Teng Y; Girvan AC; Casson LK; Pierce WM Jr; Qian M; Thomas SD; Bates PJ. AS1411 alters the localization of a complex containing protein arginine methyltransferase 5 and nucleolin. Cancer Res., 2007, 67, 10491-500. (Pubitemid 350070825)
    • (2007) Cancer Research , vol.67 , Issue.21 , pp. 10491-10500
    • Teng, Y.1    Girvan, A.C.2    Casson, L.K.3    Pierce Jr., W.M.4    Qian, M.5    Thomas, S.D.6    Bates, P.J.7
  • 111
    • 78449269097 scopus 로고    scopus 로고
    • A new paradigm for ap-tamer therapeutic AS1411 action: Uptake by macropinocytosis and its stimulation by a nucleolin-dependent mechanism
    • Reyes-Reyes E.M.; Teng Y.; Bates PJ. A new paradigm for ap-tamer therapeutic AS1411 action: uptake by macropinocytosis and its stimulation by a nucleolin-dependent mechanism. Cancer Res., 2010, 70, 8617-8629.
    • (2010) Cancer Res. , vol.70 , pp. 8617-8629
    • Reyes-Reyes, E.M.1    Teng, Y.2    Bates, P.J.3
  • 114
    • 79951581134 scopus 로고    scopus 로고
    • A graphene functionalized electrochemical aptasensor for selective label-free detection of cancer cells
    • Feng L.; Chen Y.; Ren J.; Qu X. A graphene functionalized electrochemical aptasensor for selective label-free detection of cancer cells. Biomaterials, 2011, 32, 2930-2937.
    • (2011) Biomaterials , vol.32 , pp. 2930-2937
    • Feng, L.1    Chen, Y.2    Ren, J.3    Qu, X.4
  • 115
    • 80051817418 scopus 로고    scopus 로고
    • Aptamer-functionalized PEG-PLGA nanoparti-cles for enhanced anti-glioma drug delivery
    • Guo J.; Gao X.; Su L.; Xia H.; Gu G.; Pang Z.; Jiang X.; Yao L.; Chen J.; Chen H. Aptamer-functionalized PEG-PLGA nanoparti-cles for enhanced anti-glioma drug delivery. Biomaterials, 2011, 32, 8010-8120.
    • (2011) Biomaterials , vol.32 , pp. 8010-8120
    • Guo, J.1    Gao, X.2    Su, L.3    Xia, H.4    Gu, G.5    Pang, Z.6    Jiang, X.7    Yao, L.8    Chen, J.9    Chen, H.10
  • 116
    • 84855949104 scopus 로고    scopus 로고
    • DNA G-quadruplex-templated formation of the fluorescent silver nanocluster and its application to bioimaging
    • Ai J.; Guo W.; Li B.; Li T.; Li D.; Wang E. DNA G-quadruplex-templated formation of the fluorescent silver nanocluster and its application to bioimaging. Talanta, 2012, 88, 450-455.
    • (2012) Talanta , vol.88 , pp. 450-455
    • Ai, J.1    Guo, W.2    Li, B.3    Li, T.4    Li, D.5    Wang, E.6
  • 117
    • 0027421389 scopus 로고
    • Interaction of the Neu/p185 and EGF receptor tyrosine kinases: Implications for cellular transformation and tumor therapy
    • Dougall W.C.; Qian X.; Greene M.I. Interaction of the neu/p185 and EGF receptor tyrosine kinases: implications for cellular transformation and tumor therapy. J. Cell Biochem., 1993, 53, 61-73. (Pubitemid 23287334)
    • (1993) Journal of Cellular Biochemistry , vol.53 , Issue.1 , pp. 61-73
    • Dougall, W.C.1    Qian, X.2    Greene, M.I.3
  • 118
    • 0035135632 scopus 로고    scopus 로고
    • Coexpression patterns of EGFR, HER2, HER3 and HER4 in non-melanoma skin cancer
    • DOI 10.1016/S0959-8049(00)00364-6, PII S0959804900003646
    • Krähn G.; Leiter U.; Kaskel P.; Udart M.; Utikal J.; Bezold G.; Peter R.U. Coexpression patterns of EGFR; HER2; HER3 and HER4 in non-melanoma skin cancer. Eur. J. Cancer, 2001, 37, 251-259. (Pubitemid 32144704)
    • (2001) European Journal of Cancer , vol.37 , Issue.2 , pp. 251-259
    • Krahn, G.1    Leiter, U.2    Kaskel, P.3    Udart, M.4    Utikal, J.5    Bezold, G.6    Peter, R.U.7
  • 119
    • 0034597662 scopus 로고    scopus 로고
    • Enhanced drug resistance in cells coexpressing ErbB2 with EGF receptor or ErbB3
    • Chen X.; Yeung T.K.; Wang Z. Enhanced drug resistance in cells coexpressing ErbB2 with EGF receptor or ErbB3. Biochem. Bio-phys. Res. Commun., 2000, 277, 757-763.
    • (2000) Biochem. Bio-phys. Res. Commun. , vol.277 , pp. 757-763
    • Chen, X.1    Yeung, T.K.2    Wang, Z.3
  • 121
    • 80051734768 scopus 로고    scopus 로고
    • Generation of an enriched pool of DNA aptamers for an HER2-overexpressing cell line selected by cell SELEX
    • Dastjerdi K.; Tabar G.H.; Dehghani H.; Haghparast A. Generation of an enriched pool of DNA aptamers for an HER2-overexpressing cell line selected by Cell SELEX. Biotechnol. Appl. Biochem., 2011, 58, 226-230.
    • (2011) Biotechnol. Appl. Biochem. , vol.58 , pp. 226-230
    • Dastjerdi, K.1    Tabar, G.H.2    Dehghani, H.3    Haghparast, A.4
  • 122
    • 0033729031 scopus 로고    scopus 로고
    • Multiple endocrine neoplasia type 2 and RET: From neoplasia to neurogenesis
    • Hansford J.R.; Mulligan L.M. Multiple endocrine neoplasia type 2 and RET: from neoplasia to neurogenesis. J. Med. Genet., 2000, 37, 817-827.
    • (2000) J. Med. Genet. , vol.37 , pp. 817-827
    • Hansford, J.R.1    Mulligan, L.M.2
  • 124
    • 33751002652 scopus 로고    scopus 로고
    • Effect of pharmacologic plasminogen activator inhibitor-1 inhibition on cell motility and tumor angiogenesis
    • DOI 10.1111/j.1538-7836.2006.02244.x
    • Leik C.E.; Su E.J.; Nambi P.; Crandall D.L.; Lawrence D.A. Effect of pharmacologic plasminogen activator inhibitor-1 inhibition on cell motility and tumor angiogenesis. J. Thromb. Haemost,. 2006, 4, 2710-2715. (Pubitemid 44741569)
    • (2006) Journal of Thrombosis and Haemostasis , vol.4 , Issue.12 , pp. 2710-2715
    • Leik, C.E.1    Su, E.J.2    Nambi, P.3    Crandall, D.L.4    Lawrence, D.A.5
  • 125
    • 0037175016 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 and -3 increase cell adhesion and motility of MDA-MB-435 breast cancer cells
    • DOI 10.1074/jbc.M202333200
    • Palmieri D.; Lee J.W.; Juliano R.L;. Church F.C. Plasminogen activator inhibitor-1 and -3 increase cell adhesion and motility of MDA-MB-435 breast cancer cells. J. Biol. Chem., 2002, 277, 40950-40957. (Pubitemid 35215683)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.43 , pp. 40950-40957
    • Palmieri, D.1    Lee, J.W.2    Juliano, R.L.3    Church, F.C.4
  • 129
    • 34547637867 scopus 로고    scopus 로고
    • Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102
    • DOI 10.1158/0008-5472.CAN-07-0293
    • Sennino B.; Falcon B.L.; McCauley D.; Le T.; McCauley T.; Kurz J.C.; Haskell A.; Epstein D.M.; McDonald D.M. Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102. Cancer Res., 2007, 67, 7358-7367. (Pubitemid 47206566)
    • (2007) Cancer Research , vol.67 , Issue.15 , pp. 7358-7367
    • Sennino, B.1    Falcon, B.L.2    McCauley, D.3    Le, T.4    McCauley, T.5    Kurz, J.C.6    Haskell, A.7    Epstein, D.M.8    McDonald, D.M.9
  • 131
    • 79959384972 scopus 로고    scopus 로고
    • Increased vascular delivery and efficacy of chemotherapy after inhibition of platelet-derived growth factor-B
    • Falcon B.L.; Pietras K.; Chou J.; Chen D.; Sennino B.; Hanahan D.; McDonald D.M. Increased vascular delivery and efficacy of chemotherapy after inhibition of platelet-derived growth factor-B. Am J. Pathol., 2011, 178, 2920-2930.
    • (2011) Am J. Pathol. , vol.178 , pp. 2920-2930
    • Falcon, B.L.1    Pietras, K.2    Chou, J.3    Chen, D.4    Sennino, B.5    Hanahan, D.6    McDonald, D.M.7
  • 133
    • 58149339629 scopus 로고    scopus 로고
    • A nuclease-resistant RNA aptamer specifically inhibits angiopoietin-1-mediated tie2 activation and function
    • White R.R.; Roy J.A.; Viles K.D.; Sullenger B.A.; Kontos C.D. A nuclease-resistant RNA aptamer specifically inhibits angiopoietin-1-mediated Tie2 activation and function. Angiogenesis, 2008, 11, 395-401.
    • (2008) Angiogenesis , vol.11 , pp. 395-401
    • White, R.R.1    Roy, J.A.2    Viles, K.D.3    Sullenger, B.A.4    Kontos, C.D.5
  • 135
    • 0030895244 scopus 로고    scopus 로고
    • In vivo inhibition of CD44 limits intra-abdominal spread of a human ovarian cancer xenograft in nude mice: A novel role for CD44 in the process of peritoneal implantation
    • Strobel T.; Swanson L.; Cannistra S.A. In vivo inhibition of CD44 limits intra-abdominal spread of a human ovarian cancer xenograft in nude mice: a novel role for CD44 in the process of peritoneal implantation. Cancer Res., 1997, 57, 1228-1232. (Pubitemid 27152541)
    • (1997) Cancer Research , vol.57 , Issue.7 , pp. 1228-1232
    • Strobel, T.1    Swanson, L.2    Cannistra, S.A.3
  • 138
    • 6344258588 scopus 로고    scopus 로고
    • The role of osteopontin in tumor metastasis
    • DOI 10.1016/j.jss.2004.03.028, PII S0022480404001362
    • Wai P.Y.; Kuo P.C. The role of Osteopontin in tumor metastasis. J. Surg. Res., 2004, 121, 228-241. (Pubitemid 39387464)
    • (2004) Journal of Surgical Research , vol.121 , Issue.2 , pp. 228-241
    • Wai, P.Y.1    Kuo, P.C.2
  • 139
    • 58149240891 scopus 로고    scopus 로고
    • RNA aptamer blockade of osteopontin inhibits growth and metastasis of MDA-MB231 breast cancer cells
    • Mi Z.; Guo H.; Russell M.B.; Liu Y.; Sullenger B.A.; Kuo P.C. RNA aptamer blockade of osteopontin inhibits growth and metastasis of MDA-MB231 breast cancer cells. Mol. Ther., 2009, 17, 153-161.
    • (2009) Mol. Ther. , vol.17 , pp. 153-161
    • Mi, Z.1    Guo, H.2    Russell, M.B.3    Liu, Y.4    Sullenger, B.A.5    Kuo, P.C.6
  • 140
    • 79960919903 scopus 로고    scopus 로고
    • Pharmacokinetic characterization of an RNA aptamer against os-teopontin and demonstration of in vivo efficacy in reversing growth of human breast cancer cells
    • Talbot L.J.; Mi Z.; Bhattacharya S.D.; Kim V.; Guo H.; Kuo P.C. Pharmacokinetic characterization of an RNA aptamer against os-teopontin and demonstration of in vivo efficacy in reversing growth of human breast cancer cells. Surgery, 2011, 150, 224-230.
    • (2011) Surgery , vol.150 , pp. 224-230
    • Talbot, L.J.1    Mi, Z.2    Bhattacharya, S.D.3    Kim, V.4    Guo, H.5    Kuo, P.C.6
  • 141
    • 84862850911 scopus 로고    scopus 로고
    • The role of osteopontin and osteopontin aptamer (OPN-R3) in fibroblast activity
    • Hunter C.; Bond J.; Kuo P.C.; Selim M.A.; Levinson H. The Role of Osteopontin and Osteopontin Aptamer (OPN-R3) in Fibroblast Activity. J. Surg. Res., 2011.
    • (2011) J. Surg. Res.
    • Hunter, C.1    Bond, J.2    Kuo, P.C.3    Selim, M.A.4    Levinson, H.5
  • 142
    • 84855846614 scopus 로고    scopus 로고
    • Osteopontin regulates epithelial mesenchymal transition-associated growth of hepatocellular cancer in a mouse xenograft model
    • Bhattacharya S.D.; Mi Z.; Kim V.M.; Guo H.; Talbot L.J.; Kuo P.C. Osteopontin regulates epithelial mesenchymal transition-associated growth of hepatocellular cancer in a mouse xenograft model. Ann. Surg., 2012, 255, 319-325.
    • (2012) Ann. Surg. , vol.255 , pp. 319-325
    • Bhattacharya, S.D.1    Mi, Z.2    Kim, V.M.3    Guo, H.4    Talbot, L.J.5    Kuo, P.C.6
  • 146
    • 78649937056 scopus 로고    scopus 로고
    • Metastasis-focused cell-based SELEX generates aptamers inhibiting cell migration and invasion
    • Zueva E.; Rubio L.I.; Ducongé F.; Tavitian B. Metastasis-focused cell-based SELEX generates aptamers inhibiting cell migration and invasion. Int. J. Cancer, 2011, 128, 797-804.
    • (2011) Int. J. Cancer , vol.128 , pp. 797-804
    • Zueva, E.1    Rubio, L.I.2    Ducongé, F.3    Tavitian, B.4
  • 147
    • 85011937534 scopus 로고    scopus 로고
    • In vitro selected RNA aptamer recognizing glutathione induces ROS mediated apoptosis in the human breast cancer cell line MCF 7
    • Bala J.; Bhaskar A. Varshney A.; Singh A.K.; Dey S.; Yadava P. In vitro selected RNA aptamer recognizing glutathione induces ROS mediated apoptosis in the human breast cancer cell line MCF 7. RNA Biol., 2011, 8, 101-111.
    • (2011) RNA Biol. , vol.8 , pp. 101-111
    • Bala, J.1    Bhaskar, A.2    Varshney, A.3    Singh, A.K.4    Dey, S.5    Yadava, P.6
  • 148
    • 16644376270 scopus 로고    scopus 로고
    • Targeting ku protein for sensitizing of breast cancer cells to DNA-damage
    • Zhang L.; Yoo S.; Dritschilo A.; Belyaev I.; Soldatenkov V. Targeting Ku protein for sensitizing of breast cancer cells to DNA-damage. Int. J. Mol. Med., 2004, 14, 153-159.
    • (2004) Int. J. Mol. Med. , vol.14 , pp. 153-159
    • Zhang, L.1    Yoo, S.2    Dritschilo, A.3    Belyaev, I.4    Soldatenkov, V.5
  • 149
    • 77953485565 scopus 로고    scopus 로고
    • Molecular pathways linking inflammation and cancer
    • Mantovani A. Molecular pathways linking inflammation and cancer. Curr. Mol. Med., 2010, 10, 369-373.
    • (2010) Curr. Mol. Med. , vol.10 , pp. 369-373
    • Mantovani, A.1
  • 151
    • 33645004116 scopus 로고    scopus 로고
    • Co-expression of anti-NFkappaB RNA aptamers and siRNAs leads to maximal suppression of NFkappaB activity in Mammalian cells
    • Chan R.; Gilbert M.; Thompson K.M.; Marsh H.N.; Epstein D.M.; Pendergrast P.S. Co-expression of anti-NFkappaB RNA aptamers and siRNAs leads to maximal suppression of NFkappaB activity in mammalian cells. Nucleic Acids Res., 2006, 34, e36.
    • (2006) Nucleic Acids Res. , vol.34
    • Chan, R.1    Gilbert, M.2    Thompson, K.M.3    Marsh, H.N.4    Epstein, D.M.5    Pendergrast, P.S.6
  • 152
    • 44149087131 scopus 로고    scopus 로고
    • Selection and characterization of anti-NF-αB p65 RNA aptamers
    • DOI 10.1261/rna.878908
    • Wurster S.E.; Maher L.J. 3rd. Selection and characterization of anti-NF-kappaB p65 RNA aptamers. RNA, 2008, 14, 1037-1047. (Pubitemid 351717485)
    • (2008) RNA , vol.14 , Issue.6 , pp. 1037-1047
    • Wurster, S.E.1    Maher III, L.J.2
  • 153
    • 77955125921 scopus 로고    scopus 로고
    • An RNA aptamer that selectively inhibits the enzymatic activity of protein tyrosine phosphatase 1B in vitro
    • Townshend B.; Aubry I.; Marcellus R.C.; Gehring K.; Tremblay M.L. An RNA aptamer that selectively inhibits the enzymatic activity of protein tyrosine phosphatase 1B in vitro. Chembiochem., 2010, 11, 1583-1593.
    • (2010) Chembiochem. , vol.11 , pp. 1583-1593
    • Townshend, B.1    Aubry, I.2    Marcellus, R.C.3    Gehring, K.4    Tremblay, M.L.5
  • 154
    • 77954097134 scopus 로고    scopus 로고
    • Identification of RNA aptamer specific to mutant KRAS protein
    • Jeong S.; Han S.R.; Lee Y.J.; Kim J.H.; Lee S.W. Identification of RNA aptamer specific to mutant KRAS protein. Oligonucleotides, 2010, 20, 155-161.
    • (2010) Oligonucleotides , vol.20 , pp. 155-161
    • Jeong, S.1    Han, S.R.2    Lee, Y.J.3    Kim, J.H.4    Lee, S.W.5
  • 155
    • 0037264633 scopus 로고    scopus 로고
    • Targeting RAS signalling pathways in cancer therapy
    • DOI 10.1038/nrc969
    • Downward J. Targeting RAS signalling pathways in cancer therapy. Nat. Rev. Cancer, 2003, 3, 11-22. (Pubitemid 37328883)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.1 , pp. 11-22
    • Downward, J.1
  • 156
    • 0032031484 scopus 로고    scopus 로고
    • Human cancer cell lines growth inhibition by GT(n) oligodeoxyribonucleotides recognizing single-stranded DNA-binding proteins
    • Scaggiante B.; Morassutti C.; Dapas B.; Tolazzi G.; Ustulin F.; Quadrifoglio F. Human cancer cell lines growth inhibition by GTn oligodeoxyribonucleotides recognizing single-stranded DNA-binding proteins. Eur. J. Biochem., 1998, 252, 207-215. (Pubitemid 28101995)
    • (1998) European Journal of Biochemistry , vol.252 , Issue.2 , pp. 207-215
    • Scaggiante, B.1    Morassutti, C.2    Dapas, B.3    Tolazzi, G.4    Ustulin, F.5    Quadrifoglio, F.6
  • 157
    • 0032780440 scopus 로고    scopus 로고
    • Effect of oligomer length and base substitutions on the cytotoxic activity and specific nuclear protein recognition of GTn oligonucleotides in the human leukemic CCRF-CEM cell line
    • Morassutti C.; Dapas B.; Scaggiante B.; Paroni G.; Xodo L.; Quadrifoglio F. Effect of oligomer length and base substitutions on the cytotoxic activity and specific nuclear protein recognition of GTn oligonucleotides in the human leukemic CCRF-CEM cell line. Nucleosides Nucleotides, 1999, 18, 1711-1716. (Pubitemid 29362372)
    • (1999) Nucleosides and Nucleotides , vol.18 , Issue.6-7 , pp. 1711-1716
    • Morassutti, C.1    Dapas, B.2    Scaggiante, B.3    Paroni, G.4    Xodo, L.5    Quadrifoglio, F.6
  • 158
    • 0036696980 scopus 로고    scopus 로고
    • Increase in therapeutic index of doxorubicin and vinblastine by ap-tameric oligonucleotide in human T lymphoblastic drug-sensitive and multidrug-resistant cells
    • Dapas B.; Perissin L.; Pucillo C.; Quadrifoglio F; Scaggiante B. Increase in therapeutic index of doxorubicin and vinblastine by ap-tameric oligonucleotide in human T lymphoblastic drug-sensitive and multidrug-resistant cells. Antisense Nucleic Acid Drug Dev., 2002, 12, 247-255.
    • (2002) Antisense Nucleic Acid Drug Dev. , vol.12 , pp. 247-255
    • Dapas, B.1    Perissin, L.2    Pucillo, C.3    Quadrifoglio, F.4    Scaggiante, B.5
  • 159
    • 0042769362 scopus 로고    scopus 로고
    • Identification of different isoforms of eEF1A in the nuclear fraction of human T-lymphoblastic cancer cell line specifically binding to aptameric cytotoxic GT oligomers
    • DOI 10.1046/j.1432-1033.2003.03713.x
    • Dapas B.; Tell G.; Scaloni A.; Pines A.; Ferrara L.; Quadrifoglio F.; Scaggiante B. Identification of different isoforms of eEF1A in the nuclear fraction of human T-lymphoblastic cancer cell line specifically binding to aptameric cytotoxic GT oligomers. Eur. J. Bio-chem., 2003, 270, 3251-3262. (Pubitemid 36930191)
    • (2003) European Journal of Biochemistry , vol.270 , Issue.15 , pp. 3251-3262
    • Dapas, B.1    Tell, G.2    Scaloni, A.3    Pines, A.4    Ferrara, L.5    Quadrifoglio, F.6    Scaggiante, B.7
  • 160
    • 23044467818 scopus 로고    scopus 로고
    • Aptameric GT oligomers need to be complexed to ethoxylated polyethylenimine as pre-paired duplexes to efficiently exert their cytotoxic activity in human lymphoblastic cancer cells
    • DOI 10.1016/j.biochi.2005.03.010, PII S0300908405000829
    • Scaggiante B.; Dapas B.; Perissin L.; Manzini G. Aptameric GT oligomers need to be complexed to ethoxylated polyethylenimine as pre-paired duplexes to efficiently exert their cytotoxic activity in human lymphoblastic cancer cells. Biochimie, 2005, 87, 713-723. (Pubitemid 41058902)
    • (2005) Biochimie , vol.87 , Issue.8 , pp. 713-723
    • Scaggiante, B.1    Dapas, B.2    Perissin, L.3    Manzini, G.4
  • 161
    • 33745124012 scopus 로고    scopus 로고
    • Interaction of G-rich GT oligonucleotides with nuclear-associated eEF1A is correlated with their antiproliferative effect in haematopoietic human cancer cell lines
    • DOI 10.1111/j.1742-4658.2006.05143.x
    • Scaggiante B.; Dapas B.; Grassi G.; Manzini G. Interaction of G-rich GT oligonucleotides with nuclear-associated eEF1A is correlated with their antiproliferative effect in haematopoietic human cancer cell lines. FEBS J., 2006, 273, 1350-1361. (Pubitemid 44029102)
    • (2006) FEBS Journal , vol.273 , Issue.7 , pp. 1350-1361
    • Scaggiante, B.1    Dapas, B.2    Grassi, G.3    Manzini, G.4


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