-
1
-
-
0343724354
-
Towards a new chemiotherapy: Oligodeoxynucleotide analogues as informational drugs
-
B.E. Huber. Futura Publ. Co. Inc., Mount Kisco
-
Cohen J.S. Towards a new chemiotherapy: oligodeoxynucleotide analogues as informational drugs. Huber B.E. Cancer Therapy in the Twenty-First Century, vol I., Molecular & Immunological Approaches. 1994;145-162 Futura Publ. Co. Inc., Mount Kisco.
-
(1994)
Cancer Therapy in the Twenty-First Century, Vol I., Molecular & Immunological Approaches
, pp. 145-162
-
-
Cohen, J.S.1
-
2
-
-
0027756125
-
Pharmacokinetics, biodistribution and stability of capped oligodeoxynucleotide phosphorothioates in mice
-
Temsamani J., Tang J.Y., Padmapriya A., Kubert M., Agrawal S. Pharmacokinetics, biodistribution and stability of capped oligodeoxynucleotide phosphorothioates in mice. Antisense Res. Dev. 3:1993;277-284.
-
(1993)
Antisense Res. Dev.
, vol.3
, pp. 277-284
-
-
Temsamani, J.1
Tang, J.Y.2
Padmapriya, A.3
Kubert, M.4
Agrawal, S.5
-
3
-
-
0028324788
-
Electron micrographic studies of transport of oligodeoxynucleotides across eukaryotic cell membranes
-
Zamecnik P., Aghajanian J., Zamecnik M., Goodchild J., Witman G. Electron micrographic studies of transport of oligodeoxynucleotides across eukaryotic cell membranes. Proc. Natl. Acad. Sci. USA. 91:1994;3156-3160.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3156-3160
-
-
Zamecnik, P.1
Aghajanian, J.2
Zamecnik, M.3
Goodchild, J.4
Witman, G.5
-
4
-
-
0028019410
-
Gene inhibition using antisense oligodeoxynucleotides
-
Wagner R.W. Gene inhibition using antisense oligodeoxynucleotides. Nature. 372:1994;333-335.
-
(1994)
Nature
, vol.372
, pp. 333-335
-
-
Wagner, R.W.1
-
5
-
-
0031027349
-
In vivo studies with antisense oligonucleotides
-
Akhtar S., Agrawal S. In vivo studies with antisense oligonucleotides. Trends Pharmacol. Sci. 18:1997;12-18.
-
(1997)
Trends Pharmacol. Sci.
, vol.18
, pp. 12-18
-
-
Akhtar, S.1
Agrawal, S.2
-
6
-
-
0028128457
-
Effect of unmodified triple helix-forming oligodeoxyribonucleotide targeted to human multidrug-resistance gene mdr1 in MDR cancer cells
-
Scaggiante B., Morassutti C., Tolazzi G., Michelutti A., Baccarani M., Quadrifoglio F. Effect of unmodified triple helix-forming oligodeoxyribonucleotide targeted to human multidrug-resistance gene mdr1 in MDR cancer cells. FEBS Lett. 352:1994;380-384.
-
(1994)
FEBS Lett.
, vol.352
, pp. 380-384
-
-
Scaggiante, B.1
Morassutti, C.2
Tolazzi, G.3
Michelutti, A.4
Baccarani, M.5
Quadrifoglio, F.6
-
7
-
-
0030480045
-
AG oligonucleotides form extraordinary stable triple helices with a critical RY sequence of the murine Ki-ras promoter and inhibit transcription in transfected NIH 3T3 cells
-
Alunni-Fabbroni M., Pirulli D., Manzini G., Xodo L. AG oligonucleotides form extraordinary stable triple helices with a critical RY sequence of the murine Ki-ras promoter and inhibit transcription in transfected NIH 3T3 cells. Biochemistry. 35:1996;16361-16369.
-
(1996)
Biochemistry
, vol.35
, pp. 16361-16369
-
-
Alunni-Fabbroni, M.1
Pirulli, D.2
Manzini, G.3
Xodo, L.4
-
8
-
-
0027520482
-
Characterization of a multisubunit human protein which selectively binds single stranded d(GA)n and d(GT)n sequence repeats in DNA
-
Aharoni A., Baran N., Manor H. Characterization of a multisubunit human protein which selectively binds single stranded d(GA)n and d(GT)n sequence repeats in DNA. Nucleic Acids Res. 21:1993;5221-5228.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 5221-5228
-
-
Aharoni, A.1
Baran, N.2
Manor, H.3
-
9
-
-
0026575221
-
Selection of single-stranded DNA molecules that bind and inhibit human trombin
-
Bock L.C., Griffin L.C., Latham J.A., Vermaas E.H., Toole J.J. Selection of single-stranded DNA molecules that bind and inhibit human trombin. Nature. 355:1992;564-566.
-
(1992)
Nature
, vol.355
, pp. 564-566
-
-
Bock, L.C.1
Griffin, L.C.2
Latham, J.A.3
Vermaas, E.H.4
Toole, J.J.5
-
10
-
-
0028206551
-
A sequence-specific single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif
-
Duncan R., Bazar L., Michelotti G., Tomonaga T., Krutzsch H., Avigan M., Levens D. A sequence-specific single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif. Genes Dev. 8:1994;465-480.
-
(1994)
Genes Dev.
, vol.8
, pp. 465-480
-
-
Duncan, R.1
Bazar, L.2
Michelotti, G.3
Tomonaga, T.4
Krutzsch, H.5
Avigan, M.6
Levens, D.7
-
11
-
-
0028947943
-
Regulation of mouse myelin basic protein gene transcription by a sequence-specific single-stranded DNA-binding protein in vitro
-
Stepleski A., Haas S., Amini S., Khalili K. Regulation of mouse myelin basic protein gene transcription by a sequence-specific single-stranded DNA-binding protein in vitro. Gene. 54:1995;215-218.
-
(1995)
Gene
, vol.54
, pp. 215-218
-
-
Stepleski, A.1
Haas, S.2
Amini, S.3
Khalili, K.4
-
12
-
-
0028365490
-
Cloning and characterization of a single-stranded DNA binding protein that specifically recognizes deoxycytidine stretch
-
Ito K., Sato K., Endo H. Cloning and characterization of a single-stranded DNA binding protein that specifically recognizes deoxycytidine stretch. Nucleic Acids Res. 22:1994;53-58.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 53-58
-
-
Ito, K.1
Sato, K.2
Endo, H.3
-
13
-
-
0032031484
-
Human cancer cell lines growth inhibition by GTn oligodeoxyribonucleotides recognizing single-stranded DNA-binding proteins
-
Scaggiante B., Morassutti C., Dapas B., Ustulin F., Tolazzi G., Quadrifoglio F. Human cancer cell lines growth inhibition by GTn oligodeoxyribonucleotides recognizing single-stranded DNA-binding proteins. Eur. J. Biochem. 252:1998;207-215.
-
(1998)
Eur. J. Biochem.
, vol.252
, pp. 207-215
-
-
Scaggiante, B.1
Morassutti, C.2
Dapas, B.3
Ustulin, F.4
Tolazzi, G.5
Quadrifoglio, F.6
-
14
-
-
0026356572
-
In vitro toxicology and pharmacokinetics of antisense oligonucleotides
-
Crooke M.R. In vitro toxicology and pharmacokinetics of antisense oligonucleotides. Anticancer Drug Des. 6:1991;609-646.
-
(1991)
Anticancer Drug Des.
, vol.6
, pp. 609-646
-
-
Crooke, M.R.1
-
16
-
-
0028114548
-
Effect of phosphorothioate modification of oligodeoxynucleotides on specific protein binding
-
Brown D.A., Kang S.H., Gryaznov S.M., Dedionisio L., Heidenreich O., Sullivan S., Xu X., Nerenberg M.I. Effect of phosphorothioate modification of oligodeoxynucleotides on specific protein binding. J. Biol. Chem. 269:1994;26801-26805.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26801-26805
-
-
Brown, D.A.1
Kang, S.H.2
Gryaznov, S.M.3
Dedionisio, L.4
Heidenreich, O.5
Sullivan, S.6
Xu, X.7
Nerenberg, M.I.8
-
17
-
-
0028815149
-
Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors and remove it from low affinity binding sites on extracellular matrix
-
Guvakova M.A., Yakubov L.A., Vlodavsky I., Tonkinson J.L., Stein C.A. Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors and remove it from low affinity binding sites on extracellular matrix. J. Biol. Chem. 270:1995;2620-2627.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 2620-2627
-
-
Guvakova, M.A.1
Yakubov, L.A.2
Vlodavsky, I.3
Tonkinson, J.L.4
Stein, C.A.5
-
18
-
-
0025775062
-
Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines
-
Monks A., Scudiero D., Skehan P., Shoemaker R., Paull K., Vistica D., Hose C., Langley J., Cronise P., Vaigro-Wolff A., Gray-Goodrich M., Campbell H., Mayo J., Boyd M. Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. J. Natl. Cancer Inst. 83:1991;757-766.
-
(1991)
J. Natl. Cancer Inst.
, vol.83
, pp. 757-766
-
-
Monks, A.1
Scudiero, D.2
Skehan, P.3
Shoemaker, R.4
Paull, K.5
Vistica, D.6
Hose, C.7
Langley, J.8
Cronise, P.9
Vaigro-Wolff, A.10
Gray-Goodrich, M.11
Campbell, H.12
Mayo, J.13
Boyd, M.14
-
19
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli E.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;248-252.
-
(1970)
Nature
, vol.227
, pp. 248-252
-
-
Laemmli, E.K.1
-
20
-
-
0021100690
-
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
-
Dignam J.D., Lebowitz R.M., Roeder R.G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1983;1475-1489.
-
(1983)
Nucleic Acids Res.
, vol.11
, pp. 1475-1489
-
-
Dignam, J.D.1
Lebowitz, R.M.2
Roeder, R.G.3
-
21
-
-
0017184389
-
A rapid sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford M.M. A rapid sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-252.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-252
-
-
Bradford, M.M.1
-
22
-
-
0032780440
-
Effect of oligomer length and base substitutions on the cytotoxic activity and specific nuclear protein recognition of GTn oligonucleotides in the human leukemic CCRF-CEM cell line
-
Morassutti C., Dapas B., Scaggiante B., Paroni G., Xodo L., Quadrifoglio F. Effect of oligomer length and base substitutions on the cytotoxic activity and specific nuclear protein recognition of GTn oligonucleotides in the human leukemic CCRF-CEM cell line. Nucleosides Nucleotides. 18:1999;1711-1716.
-
(1999)
Nucleosides Nucleotides
, vol.18
, pp. 1711-1716
-
-
Morassutti, C.1
Dapas, B.2
Scaggiante, B.3
Paroni, G.4
Xodo, L.5
Quadrifoglio, F.6
-
23
-
-
0026115923
-
Pathways of degradation and mechanism of action of antisense oligonucleotides in Xenopus laevis embryos
-
Dagle J.M., Weeks D.L., Walder J.A. Pathways of degradation and mechanism of action of antisense oligonucleotides in Xenopus laevis embryos. Antisense Res. Dev. 1:1991;11-20.
-
(1991)
Antisense Res. Dev.
, vol.1
, pp. 11-20
-
-
Dagle, J.M.1
Weeks, D.L.2
Walder, J.A.3
-
24
-
-
0028114572
-
Patterns of intracellular compartmentalization, trafficking and acidification of 5'-fluorescein labeled phosphodiester and phosphorothioate oligodeoxynucleotides in HL60 cells
-
Tonkinson J.L., Stein C.A. Patterns of intracellular compartmentalization, trafficking and acidification of 5'-fluorescein labeled phosphodiester and phosphorothioate oligodeoxynucleotides in HL60 cells. Nucleic Acids Res. 22:1994;4268-4275.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 4268-4275
-
-
Tonkinson, J.L.1
Stein, C.A.2
-
25
-
-
0026606235
-
The uptake kinetics of chimeric oligodeoxynucleotide analogues in human leukaemia MOLT-4 cells
-
Spiller D.G., Tidd D.M. The uptake kinetics of chimeric oligodeoxynucleotide analogues in human leukaemia MOLT-4 cells. Anticancer Drug Des. 7:1992;115-129.
-
(1992)
Anticancer Drug Des.
, vol.7
, pp. 115-129
-
-
Spiller, D.G.1
Tidd, D.M.2
-
26
-
-
0032522132
-
Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus
-
Marcusson E.G., Balkrishen B., Manoharan M., Bennett C.F., Dean N.M. Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus. Nucleic Acids Res. 26:1998;2016-2023.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 2016-2023
-
-
Marcusson, E.G.1
Balkrishen, B.2
Manoharan, M.3
Bennett, C.F.4
Dean, N.M.5
-
27
-
-
0029069493
-
Phosphorothioate oligonucleotides bind in a non sequence-specific manner to the nucleolar protein C23/nucleolin
-
Weidner D.A., Valdez B.C., Henning D., Greenberg S., Busch H. Phosphorothioate oligonucleotides bind in a non sequence-specific manner to the nucleolar protein C23/nucleolin. FEBS Lett. 366:1995;146-150.
-
(1995)
FEBS Lett.
, vol.366
, pp. 146-150
-
-
Weidner, D.A.1
Valdez, B.C.2
Henning, D.3
Greenberg, S.4
Busch, H.5
-
28
-
-
0026876215
-
Translation inhibition by phosphorothioate oligodeoxynucleotides in cell-free systems
-
Ghosh M.K., Ghosh K., Cohen J.S. Translation inhibition by phosphorothioate oligodeoxynucleotides in cell-free systems. Antisense Res. Dev. 2:1992;111-118.
-
(1992)
Antisense Res. Dev.
, vol.2
, pp. 111-118
-
-
Ghosh, M.K.1
Ghosh, K.2
Cohen, J.S.3
-
29
-
-
0029943679
-
Phosphorothioate antisense oligodeoxynucleotides: Questions of specificity
-
Stein C.A. Phosphorothioate antisense oligodeoxynucleotides: questions of specificity. TIBTECH. 14:1996;147-149.
-
(1996)
TIBTECH
, vol.14
, pp. 147-149
-
-
Stein, C.A.1
-
30
-
-
0022418143
-
Bond order and charge localization in nucleoside phosphorothioates
-
Frey P.A., Sammons R.D. Bond order and charge localization in nucleoside phosphorothioates. Science. 228:1985;541-545.
-
(1985)
Science
, vol.228
, pp. 541-545
-
-
Frey, P.A.1
Sammons, R.D.2
-
31
-
-
0028845327
-
Binding of phosphorothioate oligodeoxynucleotides to basic fibroblast growth factor, recombinant soluble CD4, laminin and fibronectin is P-chirality independent
-
Benimetskaya L., Tonkinson J.L., Koziolkiewcz M., Karwowski B., Guga P., Zeltser R., Stec W., Stein C.A. Binding of phosphorothioate oligodeoxynucleotides to basic fibroblast growth factor, recombinant soluble CD4, laminin and fibronectin is P-chirality independent. Nucleic Acids Res. 23:1995;4239-4245.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 4239-4245
-
-
Benimetskaya, L.1
Tonkinson, J.L.2
Koziolkiewcz, M.3
Karwowski, B.4
Guga, P.5
Zeltser, R.6
Stec, W.7
Stein, C.A.8
|