메뉴 건너뛰기




Volumn 15, Issue 4, 2000, Pages 343-356

Human MUC1 mucin: A multifaceted glycoprotein

Author keywords

Cancer; Glycopeptides; Immunotherapy; MUC1

Indexed keywords

BCG VACCINE; CANCER VACCINE; GANGLIOSIDE GM2; KEYHOLE LIMPET HEMOCYANIN; MANNAN; MUCIN; PEPTIDE ANTIBODY; PHOSPHORYL LIPID A; QS 21; THERATOPE; VACCINIA VACCINE;

EID: 0034522603     PISSN: 03936155     EISSN: None     Source Type: Journal    
DOI: 10.1177/172460080001500413     Document Type: Conference Paper
Times cited : (108)

References (142)
  • 32
    • 0029938677 scopus 로고    scopus 로고
    • Distinct sub-populations of carcinoma-associated MUC1 mucins as detected by the monoclonal antibody 9H8 and antibodies against the sialyl-Lewis a and sialyl-Lewis x epitopes in the circulation of breast cancer patients
    • (1996) Int J Cancer , vol.66 , pp. 617-623
    • Sikut, R.1    Zhang, K.2    Baeckstrom, D.3    Hansson, G.C.4
  • 38
    • 0021132973 scopus 로고
    • Monoclonal antibodies against human milk-fat globule membranes detecting differentiation antigens of the mammary gland and its tumors
    • (1984) Int J Cancer , vol.34 , pp. 197-206
    • Hilkens, J.1    Buijs, F.2    Hilgers, J.3
  • 41
    • 0032484230 scopus 로고    scopus 로고
    • Crystal structure at 1.95 angstrom resolution of the breast tumour-specific antibody SM3 complexed with its peptide epitope reveals novel hypervariable loop recognition
    • (1998) J Mol Biol , vol.284 , pp. 713-728
    • Dokurno, P.1    Bates, P.A.2    Band, H.A.3
  • 45
    • 0025874680 scopus 로고
    • Molecular cloning and analysis of the mouse homologue of the tumor-associated mucin, MUC1, reveals conservation of potential O-glycosylation sites, transmembrane, and cytoplasmic domains and a loss of minisatellite-like polymorphism
    • (1991) J Biol Chem , vol.266 , pp. 15099-15109
    • Spicer, A.P.1    Parry, G.2    Patton, S.3    Gendler, S.4
  • 53
    • 0033050804 scopus 로고    scopus 로고
    • MUC1 isoform specific monoclonal antibody 6E6/2 detects preferential expression of the novel MUC1/Y protein in breast and ovarian cancer
    • (1999) Int J Cancer , vol.82 , pp. 256-267
    • Hartman, M.L.1    Baruch, A.2    Ron, I.3
  • 55
    • 0020083273 scopus 로고
    • Isolation and characterisation of mucin-like glycoprotein in human milk fat globule membrane
    • (1982) J Biochem , vol.91 , pp. 515-524
    • Shimizu, M.1    Yamauchi, K.2
  • 57
    • 0030798627 scopus 로고    scopus 로고
    • Substrate specificities of three members of the human UDP-N-acetyl α-D-galactosamine: Polypeptide N-acetylgalactosaminyltransferase family, GalNac-T1, -T2, and -T3
    • (1997) J Biol Chem , vol.272 , pp. 23503-23514
    • Wandall, H.H.1    Hassan, H.2    Mirgorodskaya, E.3
  • 58
    • 15444344929 scopus 로고    scopus 로고
    • Cloning of a human UDP-N-acetyl-alpha-D galactosamine-polypeptide N-acetyl-galactosaminyltransferase that complements other GalNAc-transferases in complete O-glycosylation of the MUC1 tandem repeat
    • (1998) Biol Chem , vol.273 , pp. 30472-30481
    • Bennett, E.P.1    Hassan, H.2    Mandel, U.3
  • 61
    • 0039374466 scopus 로고    scopus 로고
    • Dynamic epigenetic regulation of initial O-glycosylation by UDP-N-acetyl-galactosamine: Peptide N acetylgalactosaminyltransferases - Site-specific glycosylation of MUC1 repeat peptide influences the substrate qualities at adjacent orw distant Ser/Thr positions
    • (1999) J Biol Chem , vol.274 , pp. 9946-9954
    • Hanisch, F.G.1    Muller, S.2    Hassan, H.3
  • 65
    • 0028824558 scopus 로고
    • T and Tn pancarcinoma markers: Autoantigenic adhesion molecules in pathogenesis, prebiopsy carcinoma-detection, and long-term breast carcinoma immunotherapy
    • (1995) Critical Rev Oncog , vol.6 , pp. 57-85
    • Springer, G.F.1
  • 69
    • 0028989972 scopus 로고
    • Approaches to augmenting the immunogenicity of melanoma gangliosides: From whole melanoma cells to ganglioside-KLH conjugate vaccines
    • (1995) Immunol Rev , vol.145 , pp. 145-166
    • Livingston, P.O.1
  • 80
    • 0029988114 scopus 로고    scopus 로고
    • Secreted MUC1 mucins lacking their cytoplasmic part and carrying sialyl-Lewis a and x epitopes from a tumour cell line and sera of colon carcinoma patients can inhibit HL-60 leukocyte adhesion to E selectin-expressing endothelial cells
    • (1996) J Cell Biochem , vol.60 , pp. 538-549
    • Zhang, K.1    Baeckstrom, D.2    Brevinge, H.3    Hansson, G.C.4
  • 94
  • 101
    • 0030298428 scopus 로고    scopus 로고
    • Human antibodies against the polymorphic epithelial mucin in ovarian cancer patients recognise a novel sequence in the tandem repeat region
    • (1996) Eur J Cancer , vol.32 A , pp. 2155-2163
    • Petrarca, C.1    Rughetti, A.2    Rahimi, H.3
  • 111
    • 0025834851 scopus 로고
    • Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognize an epitope present on the protein core of a mucin molecule preferentially expressed by malignant cells
    • (1991) Cancer Res , vol.51 , pp. 2908-2916
    • Jerome, K.R.1    Barnd, D.L.2    Bendt, K.M.3
  • 113
    • 0027321847 scopus 로고
    • Tumor-specific cytotoxic T cell clones from patients with breast and pancreatic adenocarcinoma recognize EBV-immortalized B cells transfected with polymorphic epithelial mucin complementary DNA
    • (1993) J Immunol , vol.151 , pp. 1654-1662
    • Jerome, K.R.1    Domenech, N.2    Finn, O.J.3
  • 119
    • 0033564363 scopus 로고    scopus 로고
    • Identification of HLAA-A2 restricted T-cell epitopes derived from the MUC1 tumor antigen for broadly applicable vaccine therapies
    • (1999) Blood , vol.93 , pp. 4309-4317
    • Brossart, P.1    Heinrich, K.S.2    Stuhler, G.3
  • 124
    • 0031451498 scopus 로고    scopus 로고
    • Therapeutic antitumor response after immunization with an admixture of recombinant vaccinia virus expressing a modified MUC1 gene and the murine T-cell costimulatory molecule B7
    • (1997) J Immunother , vol.20 , pp. 38-47
    • Akagi, J.1    Hodge, J.W.2    Mclaughlin, J.P.3
  • 135
    • 0029918564 scopus 로고    scopus 로고
    • Induction of cellular immunity in chimpanzees to human tumor-associated antigen mucin by vaccination with MUC-I cDNA-transfected Epstein Barr virus-immortalized autologous B cells
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1699-1704
    • Pecher, G.1    Finn, O.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.