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Volumn 99, Issue 13, 2002, Pages 8898-8902
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In vivo properties of an anti-GnRH Spiegelmer: An example of an oligonucleotide-based therapeutic substance class
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Author keywords
Animal model; Aptamer; Immunogenicity; In vitro selection; Mirror image oligonucleotide
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Indexed keywords
GONADORELIN;
GONADORELIN ANTAGONIST;
GONADORELIN RECEPTOR;
MACROGOL;
NOX 1255;
NOX 1257;
OLIGONUCLEOTIDE;
PEPTIDE HORMONE;
SPIEGELMER;
UNCLASSIFIED DRUG;
ANIMAL CELL;
ANIMAL EXPERIMENT;
ARTICLE;
BINDING AFFINITY;
CASTRATION;
CHO CELL;
DRUG EFFECT;
DRUG SYNTHESIS;
IMMUNOGENICITY;
MALE;
NONHUMAN;
PRIORITY JOURNAL;
RABBIT;
RAT;
ANIMALS;
BASE SEQUENCE;
CHO CELLS;
CRICETINAE;
DNA PRIMERS;
GONADOTROPIN-RELEASING HORMONE;
MALE;
OLIGONUCLEOTIDES;
RABBITS;
RATS;
ANIMALIA;
CRICETINAE;
CRICETULUS GRISEUS;
ORYCTOLAGUS CUNICULUS;
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EID: 0037173068
PISSN: 00278424
EISSN: None
Source Type: Journal
DOI: 10.1073/pnas.132067399 Document Type: Article |
Times cited : (168)
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References (24)
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