-
1
-
-
33746503823
-
Shape-shifting serpins: Advantages of a mobile mechanism
-
Huntington, J. A. (2006) Shape-shifting serpins: Advantages of a mobile mechanism Trends Biochem. Sci. 31, 427-435
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 427-435
-
-
Huntington, J.A.1
-
2
-
-
63849264516
-
Biochemical properties of plasminogen activator inhibitor-1
-
Dupont, D. M., Madsen, J. B., Kristensen, T., Bodker, J. S., Blouse, G. E., Wind, T., and Andreasen, P. A. (2009) Biochemical properties of plasminogen activator inhibitor-1 Front. Biosci. 14, 1337-1361
-
(2009)
Front. Biosci.
, vol.14
, pp. 1337-1361
-
-
Dupont, D.M.1
Madsen, J.B.2
Kristensen, T.3
Bodker, J.S.4
Blouse, G.E.5
Wind, T.6
Andreasen, P.A.7
-
3
-
-
0036005954
-
The molecular basis for anti-proteolytic and non-proteolytic functions of plasminogen activator inhibitor type-1: Roles of the reactive centre loop, the shutter region, the flexible joint region and the small serpin fragment
-
Wind, T., Hansen, M., Jensen, J. K., and Andreasen, P. A. (2002) The molecular basis for anti-proteolytic and non-proteolytic functions of plasminogen activator inhibitor type-1: Roles of the reactive centre loop, the shutter region, the flexible joint region and the small serpin fragment Biol. Chem. 383, 21-36
-
(2002)
Biol. Chem.
, vol.383
, pp. 21-36
-
-
Wind, T.1
Hansen, M.2
Jensen, J.K.3
Andreasen, P.A.4
-
4
-
-
0033981473
-
The plasminogen activation system in tumor growth, invasion, and metastasis
-
Andreasen, P. A., Egelund, R., and Petersen, H. H. (2000) The plasminogen activation system in tumor growth, invasion, and metastasis Cell. Mol. Life Sci. 57, 25-40
-
(2000)
Cell. Mol. Life Sci.
, vol.57
, pp. 25-40
-
-
Andreasen, P.A.1
Egelund, R.2
Petersen, H.H.3
-
5
-
-
0028028391
-
The multiligand α2-macroglobulin receptor/low density lipoprotein receptor-related protein (α2MR/LRP). Binding and endocytosis of fluid phase and membrane-associated ligands
-
Gliemann, J., Nykjaer, A., Petersen, C. M., Jorgensen, K. E., Nielsen, M., Andreasen, P. A., Christensen, E. I., Lookene, A., Olivecrona, G., and Moestrup, S. K. (1994) The multiligand α2-macroglobulin receptor/low density lipoprotein receptor-related protein (α2MR/LRP). Binding and endocytosis of fluid phase and membrane-associated ligands Ann. N.Y. Acad. Sci. 737, 20-38
-
(1994)
Ann. N.Y. Acad. Sci.
, vol.737
, pp. 20-38
-
-
Gliemann, J.1
Nykjaer, A.2
Petersen, C.M.3
Jorgensen, K.E.4
Nielsen, M.5
Andreasen, P.A.6
Christensen, E.I.7
Lookene, A.8
Olivecrona, G.9
Moestrup, S.K.10
-
6
-
-
67650538093
-
Specificity of binding of the low density lipoprotein receptor-related protein to different conformational states of the clade e serpins plasminogen activator inhibitor-1 and proteinase nexin-1
-
Jensen, J. K., Dolmer, K., and Gettins, P. G. (2009) Specificity of binding of the low density lipoprotein receptor-related protein to different conformational states of the clade E serpins plasminogen activator inhibitor-1 and proteinase nexin-1 J. Biol. Chem. 284, 17989-17997
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 17989-17997
-
-
Jensen, J.K.1
Dolmer, K.2
Gettins, P.G.3
-
7
-
-
0028208975
-
Urokinase receptor. An activation antigen in human T lymphocytes
-
Nykjaer, A., Moller, B., Todd, R. F., III, Christensen, T., Andreasen, P. A., Gliemann, J., and Petersen, C. M. (1994) Urokinase receptor. An activation antigen in human T lymphocytes J. Immunol. 152, 505-516
-
(1994)
J. Immunol.
, vol.152
, pp. 505-516
-
-
Nykjaer, A.1
Moller, B.2
Todd III, R.F.3
Christensen, T.4
Andreasen, P.A.5
Gliemann, J.6
Petersen, C.M.7
-
8
-
-
0001353920
-
Purified α2-macroglobulin receptor/LDL receptor-related protein binds urokinase-plasminogen activator inhibitor type-1 complex. Evidence that the α2-macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes
-
Nykjaer, A., Petersen, C. M., Moller, B., Jensen, P. H., Moestrup, S. K., Holtet, T. L., Etzerodt, M., Thogersen, H. C., Munch, M., and Andreasen, P. A. 1992, Purified α2-macroglobulin receptor/LDL receptor-related protein binds urokinase-plasminogen activator inhibitor type-1 complex. Evidence that the α2-macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes J. Biol. Chem. 267, 14543-14546
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 14543-14546
-
-
Nykjaer, A.1
Petersen, C.M.2
Moller, B.3
Jensen, P.H.4
Moestrup, S.K.5
Holtet, T.L.6
Etzerodt, M.7
Thogersen, H.C.8
Munch, M.9
Andreasen, P.A.10
-
9
-
-
12144289397
-
Plasminogen activator inhibitor-1 and tumour growth, invasion, and metastasis
-
Durand, M. K., Bodker, J. S., Christensen, A., Dupont, D. M., Hansen, M., Jensen, J. K., Kjelgaard, S., Mathiasen, L., Pedersen, K. E., Skeldal, S., Wind, T., and Andreasen, P. A. (2004) Plasminogen activator inhibitor-I and tumour growth, invasion, and metastasis Thromb. Haemostasis 91, 438-449 (Pubitemid 38396865)
-
(2004)
Thrombosis and Haemostasis
, vol.91
, Issue.3
, pp. 438-449
-
-
Durand, M.K.V.1
Bodker, J.S.2
Christensen, A.3
Dupont, D.M.4
Hansen, M.5
Jensen, J.K.6
Kjelgaard, S.7
Mathiasen, L.8
Pedersen, K.E.9
Skeldal, S.10
Wind, T.11
Andreasen, P.A.12
-
11
-
-
0035975586
-
Plasminogen activator inhibitor type-1 in cardiovascular disease. Status report 2001
-
Huber, K., Christ, G., Wojta, J., and Gulba, D. (2001) Plasminogen activator inhibitor type-1 in cardiovascular disease. Status report 2001 Thromb. Res. 103 (Suppl. 1) S7-S19
-
(2001)
Thromb. Res.
, vol.103
, Issue.SUPPL. 1
-
-
Huber, K.1
Christ, G.2
Wojta, J.3
Gulba, D.4
-
12
-
-
0036154210
-
Angiotensin and vascular fibrinolytic balance
-
Vaughan, D. E. (2002) Angiotensin and vascular fibrinolytic balance Am. J. Hypertens. 15, 3S-8S
-
(2002)
Am. J. Hypertens.
, vol.15
-
-
Vaughan, D.E.1
-
13
-
-
0025371467
-
Development of venous occlusions in mice transgenic for the plasminogen activator inhibitor-1 gene
-
Erickson, L. A., Fici, G. J., Lund, J. E., Boyle, T. P., Polites, H. G., and Marotti, K. R. (1990) Development of venous occlusions in mice transgenic for the plasminogen activator inhibitor-1 gene Nature 346, 74-76
-
(1990)
Nature
, vol.346
, pp. 74-76
-
-
Erickson, L.A.1
Fici, G.J.2
Lund, J.E.3
Boyle, T.P.4
Polites, H.G.5
Marotti, K.R.6
-
14
-
-
0037162388
-
Age-dependent spontaneous coronary arterial thrombosis in transgenic mice that express a stable form of human plasminogen activator inhibitor-1
-
Eren, M., Painter, C. A., Atkinson, J. B., Declerck, P. J., and Vaughan, D. E. (2002) Age-dependent spontaneous coronary arterial thrombosis in transgenic mice that express a stable form of human plasminogen activator inhibitor-1 Circulation 106, 491-496
-
(2002)
Circulation
, vol.106
, pp. 491-496
-
-
Eren, M.1
Painter, C.A.2
Atkinson, J.B.3
Declerck, P.J.4
Vaughan, D.E.5
-
15
-
-
0030788411
-
The urokinase-type plasminogen activator system in cancer metastasis: A review
-
Andreasen, P. A., Kjoller, L., Christensen, L., and Duffy, M. J. (1997) The urokinase-type plasminogen activator system in cancer metastasis: a review Int. J. Cancer 72, 1-22
-
(1997)
Int. J. Cancer
, vol.72
, pp. 1-22
-
-
Andreasen, P.A.1
Kjoller, L.2
Christensen, L.3
Duffy, M.J.4
-
16
-
-
0035918882
-
Randomized adjuvant chemotherapy trial in high-risk, lymph node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type 1
-
Janicke, F., Prechtl, A., Thomssen, C., Harbeck, N., Meisner, C., Untch, M., Sweep, C. G., Selbmann, H. K., Graeff, H., and Schmitt, M. (2001) Randomized adjuvant chemotherapy trial in high-risk, lymph node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type 1 J. Natl. Cancer Inst. 93, 913-920
-
(2001)
J. Natl. Cancer Inst.
, vol.93
, pp. 913-920
-
-
Janicke, F.1
Prechtl, A.2
Thomssen, C.3
Harbeck, N.4
Meisner, C.5
Untch, M.6
Sweep, C.G.7
Selbmann, H.K.8
Graeff, H.9
Schmitt, M.10
-
17
-
-
0037116616
-
Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients
-
Look, M. P., van Putten, W. L., Duffy, M. J., Harbeck, N., Christensen, I. J., Thomssen, C., Kates, R., Spyratos, F., Ferno, M., Eppenberger-Castori, S., Sweep, C. G., Ulm, K., Peyrat, J. P., Martin, P. M., Magdelenat, H., Brunner, N., Duggan, C., Lisboa, B. W., Bendahl, P. O., Quillien, V., Daver, A., Ricolleau, G., Meijer-van Gelder, M. E., Manders, P., Fiets, W. E., Blankenstein, M. A., Broet, P., Romain, S., Daxenbichler, G., Windbichler, G., Cufer, T., Borstnar, S., Kueng, W., Beex, L. V., Klijn, J. G., O'Higgins, N., Eppenberger, U., Janicke, F., Schmitt, M., and Foekens, J. A. (2002) Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients J. Natl. Cancer Inst. 94, 116-128
-
(2002)
J. Natl. Cancer Inst.
, vol.94
, pp. 116-128
-
-
Look, M.P.1
Van Putten, W.L.2
Duffy, M.J.3
Harbeck, N.4
Christensen, I.J.5
Thomssen, C.6
Kates, R.7
Spyratos, F.8
Ferno, M.9
Eppenberger-Castori, S.10
Sweep, C.G.11
Ulm, K.12
Peyrat, J.P.13
Martin, P.M.14
Magdelenat, H.15
Brunner, N.16
Duggan, C.17
Lisboa, B.W.18
Bendahl, P.O.19
Quillien, V.20
Daver, A.21
Ricolleau, G.22
Meijer-Van Gelder, M.E.23
Manders, P.24
Fiets, W.E.25
Blankenstein, M.A.26
Broet, P.27
Romain, S.28
Daxenbichler, G.29
Windbichler, G.30
Cufer, T.31
Borstnar, S.32
Kueng, W.33
Beex, L.V.34
Klijn, J.G.35
O'Higgins, N.36
Eppenberger, U.37
Janicke, F.38
Schmitt, M.39
Foekens, J.A.40
more..
-
18
-
-
35348834104
-
PAI-1: A potential therapeutic target in cancer
-
Andreasen, P. A. (2007) PAI-1: A potential therapeutic target in cancer Curr. Drug Targets 8, 1030-1041
-
(2007)
Curr. Drug Targets
, vol.8
, pp. 1030-1041
-
-
Andreasen, P.A.1
-
19
-
-
0032853242
-
In vitro selection of functional nucleic acids
-
Wilson, D. S. and Szostak, J. W. (1999) In vitro selection of functional nucleic acids Annu. Rev. Biochem. 68, 611-647
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 611-647
-
-
Wilson, D.S.1
Szostak, J.W.2
-
20
-
-
24744466474
-
Aptamers against extracellular targets for in vivo applications
-
Pestourie, C., Tavitian, B., and Duconge, F. (2005) Aptamers against extracellular targets for in vivo applications Biochimie 87, 921-930
-
(2005)
Biochimie
, vol.87
, pp. 921-930
-
-
Pestourie, C.1
Tavitian, B.2
Duconge, F.3
-
21
-
-
0037134909
-
The vitronectin binding area of plasminogen activator inhibitor-1, mapped by mutagenesis and protection against an inactivating organochemical ligand
-
Jensen, J. K., Wind, T., and Andreasen, P. A. (2002) The vitronectin binding area of plasminogen activator inhibitor-1, mapped by mutagenesis and protection against an inactivating organochemical ligand FEBS Lett. 521, 91-94
-
(2002)
FEBS Lett.
, vol.521
, pp. 91-94
-
-
Jensen, J.K.1
Wind, T.2
Andreasen, P.A.3
-
22
-
-
0027290655
-
Interconversions between active, inert and substrate forms of denatured/refolded type-1 plasminogen activator inhibitor
-
Munch, M., Heegaard, C. W., and Andreasen, P. A. (1993) Interconversions between active, inert and substrate forms of denatured/refolded type-1 plasminogen activator inhibitor Biochim. Biophys. Acta 1202, 29-37
-
(1993)
Biochim. Biophys. Acta
, vol.1202
, pp. 29-37
-
-
Munch, M.1
Heegaard, C.W.2
Andreasen, P.A.3
-
23
-
-
0035210951
-
Importance of the amino-acid composition of the shutter region of plasminogen activator inhibitor-1 for its transitions to latent and substrate forms
-
Hansen, M., Busse, M. N., and Andreasen, P. A. (2001) Importance of the amino-acid composition of the shutter region of plasminogen activator inhibitor-1 for its transitions to latent and substrate forms Eur. J. Biochem. 268, 6274-6283
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 6274-6283
-
-
Hansen, M.1
Busse, M.N.2
Andreasen, P.A.3
-
24
-
-
0142095053
-
Mutation of the highly conserved tryptophan in the serpin breach region alters the inhibitory mechanism of plasminogen activator inhibitor-1
-
Blouse, G. E., Perron, M. J., Kvassman, J. O., Yunus, S., Thompson, J. H., Betts, R. L., Lutter, L. C., and Shore, J. D. (2003) Mutation of the highly conserved tryptophan in the serpin breach region alters the inhibitory mechanism of plasminogen activator inhibitor-1 Biochemistry 42, 12260-12272
-
(2003)
Biochemistry
, vol.42
, pp. 12260-12272
-
-
Blouse, G.E.1
Perron, M.J.2
Kvassman, J.O.3
Yunus, S.4
Thompson, J.H.5
Betts, R.L.6
Lutter, L.C.7
Shore, J.D.8
-
25
-
-
0022887824
-
Plasminogen activator inhibitor type-1: Reactive center and amino-terminal heterogeneity determined by protein and cDNA sequencing
-
Andreasen, P. A., Riccio, A., Welinder, K. G., Douglas, R., Sartorio, R., Nielsen, L. S., Oppenheimer, C., Blasi, F., and Dano, K. (1986) Plasminogen activator inhibitor type-1: Reactive center and amino-terminal heterogeneity determined by protein and cDNA sequencing FEBS Lett. 209, 213-218
-
(1986)
FEBS Lett.
, vol.209
, pp. 213-218
-
-
Andreasen, P.A.1
Riccio, A.2
Welinder, K.G.3
Douglas, R.4
Sartorio, R.5
Nielsen, L.S.6
Oppenheimer, C.7
Blasi, F.8
Dano, K.9
-
26
-
-
0038071492
-
Mutational analysis of plasminogen activator inhibitor-1
-
Wind, T., Jensen, J. K., Dupont, D. M., Kulig, P., and Andreasen, P. A. (2003) Mutational analysis of plasminogen activator inhibitor-1 Eur. J. Biochem. 270, 1680-1688
-
(2003)
Eur. J. Biochem.
, vol.270
, pp. 1680-1688
-
-
Wind, T.1
Jensen, J.K.2
Dupont, D.M.3
Kulig, P.4
Andreasen, P.A.5
-
27
-
-
0028912190
-
A fluorescent probe study of plasminogen activator inhibitor-1. Evidence for reactive center loop insertion and its role in the inhibitory mechanism
-
Shore, J. D., Day, D. E., Francis-Chmura, A. M., Verhamme, I., Kvassman, J., Lawrence, D. A., and Ginsburg, D. (1995) A fluorescent probe study of plasminogen activator inhibitor-1. Evidence for reactive center loop insertion and its role in the inhibitory mechanism J. Biol. Chem. 270, 5395-5398
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 5395-5398
-
-
Shore, J.D.1
Day, D.E.2
Francis-Chmura, A.M.3
Verhamme, I.4
Kvassman, J.5
Lawrence, D.A.6
Ginsburg, D.7
-
28
-
-
0034832458
-
A serpin-induced extensive proteolytic susceptibility of urokinase-type plasminogen activator implicates distortion of the proteinase substrate-binding pocket and oxyanion hole in the serpin inhibitory mechanism
-
Egelund, R., Petersen, T. E., and Andreasen, P. A. (2001) A serpin-induced extensive proteolytic susceptibility of urokinase-type plasminogen activator implicates distortion of the proteinase substrate-binding pocket and oxyanion hole in the serpin inhibitory mechanism Eur. J. Biochem. 268, 673-685
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 673-685
-
-
Egelund, R.1
Petersen, T.E.2
Andreasen, P.A.3
-
29
-
-
0030886795
-
Specificity of serine proteinase/serpin complex binding to very-low-density lipoprotein receptor and α2-macroglobulin receptor/low-density-lipoprotein-receptor-related protein
-
Kasza, A., Petersen, H. H., Heegaard, C. W., Oka, K., Christensen, A., Dubin, A., Chan, L., and Andreasen, P. A. (1997) Specificity of serine proteinase/serpin complex binding to very-low-density lipoprotein receptor and α2-macroglobulin receptor/low-density-lipoprotein-receptor-related protein Eur. J. Biochem. 248, 270-281
-
(1997)
Eur. J. Biochem.
, vol.248
, pp. 270-281
-
-
Kasza, A.1
Petersen, H.H.2
Heegaard, C.W.3
Oka, K.4
Christensen, A.5
Dubin, A.6
Chan, L.7
Andreasen, P.A.8
-
30
-
-
0032665626
-
In vitro selection of aptamers from RNA libraries
-
Kenan, D. J. and Keene, J. D. (1999) In vitro selection of aptamers from RNA libraries Methods Mol. Biol. 118, 217-231
-
(1999)
Methods Mol. Biol.
, vol.118
, pp. 217-231
-
-
Kenan, D.J.1
Keene, J.D.2
-
31
-
-
0023840230
-
OmpT encodes the Escherichia coli outer membrane protease that cleaves T7 RNA polymerase during purification
-
Grodberg, J. and Dunn, J. J. (1988) ompT encodes the Escherichia coli outer membrane protease that cleaves T7 RNA polymerase during purification J. Bacteriol. 170, 1245-1253
-
(1988)
J. Bacteriol.
, vol.170
, pp. 1245-1253
-
-
Grodberg, J.1
Dunn, J.J.2
-
32
-
-
0025760054
-
Rapid and simple purification of T7 RNA polymerase
-
Zawadzki, V. and Gross, H. J. (1991) Rapid and simple purification of T7 RNA polymerase Nucleic Acids Res. 19, 1948
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 1948
-
-
Zawadzki, V.1
Gross, H.J.2
-
33
-
-
0042121256
-
Mfold web server for nucleic acid folding and hybridization prediction
-
Zuker, M. (2003) Mfold web server for nucleic acid folding and hybridization prediction Nucleic Acids Res. 31, 3406-3415
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 3406-3415
-
-
Zuker, M.1
-
34
-
-
0033591465
-
Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure
-
Mathews, D. H., Sabina, J., Zuker, M., and Turner, D. H. (1999) Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure J. Mol. Biol. 288, 911-940
-
(1999)
J. Mol. Biol.
, vol.288
, pp. 911-940
-
-
Mathews, D.H.1
Sabina, J.2
Zuker, M.3
Turner, D.H.4
-
35
-
-
0038071502
-
Mapping of the epitope of a monoclonal antibody protecting plasminogen activator inhibitor-1 against inactivating agents
-
Bodker, J. S., Wind, T., Jensen, J. K., Hansen, M., Pedersen, K. E., and Andreasen, P. A. (2003) Mapping of the epitope of a monoclonal antibody protecting plasminogen activator inhibitor-1 against inactivating agents Eur. J. Biochem. 270, 1672-1679
-
(2003)
Eur. J. Biochem.
, vol.270
, pp. 1672-1679
-
-
Bodker, J.S.1
Wind, T.2
Jensen, J.K.3
Hansen, M.4
Pedersen, K.E.5
Andreasen, P.A.6
-
36
-
-
0019617028
-
Tertiary structure of tRNAs in solution monitored by phosphodiester modification with ethylnitrosourea
-
Vlassov, V. V., Giege, R., and Ebel, J. P. (1981) Tertiary structure of tRNAs in solution monitored by phosphodiester modification with ethylnitrosourea Eur. J. Biochem. 119, 51-59
-
(1981)
Eur. J. Biochem.
, vol.119
, pp. 51-59
-
-
Vlassov, V.V.1
Giege, R.2
Ebel, J.P.3
-
37
-
-
0034635357
-
Serine 380 (P14) → glutamate mutation activates antithrombin as an inhibitor of factor Xa
-
Futamura, A. and Gettins, P. G. (2000) Serine 380 (P14) → glutamate mutation activates antithrombin as an inhibitor of factor Xa J. Biol. Chem. 275, 4092-4098
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 4092-4098
-
-
Futamura, A.1
Gettins, P.G.2
-
38
-
-
0029113646
-
Very low density lipoprotein receptor binds and mediates endocytosis of urokinase-type plasminogen activator-type-1 plasminogen activator inhibitor complex
-
Heegaard, C. W., Simonsen, A. C., Oka, K., Kjoller, L., Christensen, A., Madsen, B., Ellgaard, L., Chan, L., and Andreasen, P. A. (1995) Very low density lipoprotein receptor binds and mediates endocytosis of urokinase-type plasminogen activator-type-1 plasminogen activator inhibitor complex J. Biol. Chem. 270, 20855-20861
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 20855-20861
-
-
Heegaard, C.W.1
Simonsen, A.C.2
Oka, K.3
Kjoller, L.4
Christensen, A.5
Madsen, B.6
Ellgaard, L.7
Chan, L.8
Andreasen, P.A.9
-
39
-
-
0023692212
-
Plasminogen activator inhibitor type 1: Cell-specific and differentiation-induced expression and regulation in human cell lines, as determined by enzyme-linked immunosorbent assay
-
Lund, L. R., Georg, B., Nielsen, L. S., Mayer, M., Dano, K., and Andreasen, P. A. (1988) Plasminogen activator inhibitor type 1: Cell-specific and differentiation-induced expression and regulation in human cell lines, as determined by enzyme-linked immunosorbent assay Mol. Cell. Endocrinol. 60, 43-53
-
(1988)
Mol. Cell. Endocrinol.
, vol.60
, pp. 43-53
-
-
Lund, L.R.1
Georg, B.2
Nielsen, L.S.3
Mayer, M.4
Dano, K.5
Andreasen, P.A.6
-
40
-
-
0028062021
-
r 40,000 receptor associated protein
-
r 40,000 receptor associated protein FEBS Lett. 354, 279-283
-
(1994)
FEBS Lett.
, vol.354
, pp. 279-283
-
-
Simonsen, A.C.1
Heegaard, C.W.2
Rasmussen, L.K.3
Ellgaard, L.4
Kjoller, L.5
Christensen, A.6
Etzerodt, M.7
Andreasen, P.A.8
-
41
-
-
0029022692
-
Molecular evolution of plasminogen activator inhibitor-1 functional stability
-
Berkenpas, M. B., Lawrence, D. A., and Ginsburg, D. (1995) Molecular evolution of plasminogen activator inhibitor-1 functional stability EMBO J. 14, 2969-2977
-
(1995)
EMBO J.
, vol.14
, pp. 2969-2977
-
-
Berkenpas, M.B.1
Lawrence, D.A.2
Ginsburg, D.3
-
42
-
-
0347355503
-
Construction of a plasminogen activator inhibitor-1 variant without measurable affinity to vitronectin but otherwise normal
-
Jensen, J. K., Durand, M. K., Skeldal, S., Dupont, D. M., Bodker, J. S., Wind, T., and Andreasen, P. A. (2004) Construction of a plasminogen activator inhibitor-1 variant without measurable affinity to vitronectin but otherwise normal FEBS Lett. 556, 175-179
-
(2004)
FEBS Lett.
, vol.556
, pp. 175-179
-
-
Jensen, J.K.1
Durand, M.K.2
Skeldal, S.3
Dupont, D.M.4
Bodker, J.S.5
Wind, T.6
Andreasen, P.A.7
-
43
-
-
44849086179
-
A deletion mutant of vitronectin lacking the somatomedin B domain exhibits residual plasminogen activator inhibitor-1-binding activity
-
Schar, C. R., Blouse, G. E., Minor, K. H., and Peterson, C. B. (2008) A deletion mutant of vitronectin lacking the somatomedin B domain exhibits residual plasminogen activator inhibitor-1-binding activity J. Biol. Chem. 283, 10297-10309
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 10297-10309
-
-
Schar, C.R.1
Blouse, G.E.2
Minor, K.H.3
Peterson, C.B.4
-
44
-
-
0028912190
-
A fluorescent probe study of plasminogen activator inhibitor-1. Evidence for reactive center loop insertion and its role in the inhibitory mechanism
-
Shore, J. D., Day, D. E., Francis-Chmura, A. M., Verhamme, I., Kvassman, J., Lawrence, D. A., and Ginsburg, D. (1995) A fluorescent probe study of plasminogen activator inhibitor-1. Evidence for reactive center loop insertion and its role in the inhibitory mechanism J. Biol. Chem. 270, 5395-5398
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 5395-5398
-
-
Shore, J.D.1
Day, D.E.2
Francis-Chmura, A.M.3
Verhamme, I.4
Kvassman, J.5
Lawrence, D.A.6
Ginsburg, D.7
-
45
-
-
0025226070
-
Structural transition of α1-antitrypsin by a peptide sequentially similar to β-strand s4A
-
Schulze, A. J., Baumann, U., Knof, S., Jaeger, E., Huber, R., and Laurell, C. B. (1990) Structural transition of α1-antitrypsin by a peptide sequentially similar to β-strand s4A Eur. J. Biochem. 194, 51-56
-
(1990)
Eur. J. Biochem.
, vol.194
, pp. 51-56
-
-
Schulze, A.J.1
Baumann, U.2
Knof, S.3
Jaeger, E.4
Huber, R.5
Laurell, C.B.6
-
46
-
-
0032524769
-
Interfering with the inhibitory mechanism of serpins: Crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide
-
Xue, Y., Bjorquist, P., Inghardt, T., Linschoten, M., Musil, D., Sjolin, L., and Deinum, J. (1998) Interfering with the inhibitory mechanism of serpins: Crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide Structure 6, 627-636
-
(1998)
Structure
, vol.6
, pp. 627-636
-
-
Xue, Y.1
Bjorquist, P.2
Inghardt, T.3
Linschoten, M.4
Musil, D.5
Sjolin, L.6
Deinum, J.7
-
47
-
-
49649124939
-
Structural differences between active forms of plasminogen activator inhibitor type 1 revealed by conformationally sensitive ligands
-
Li, S. H., Gorlatova, N. V., Lawrence, D. A., and Schwartz, B. S. (2008) Structural differences between active forms of plasminogen activator inhibitor type 1 revealed by conformationally sensitive ligands J. Biol. Chem. 283, 18147-18157
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 18147-18157
-
-
Li, S.H.1
Gorlatova, N.V.2
Lawrence, D.A.3
Schwartz, B.S.4
-
48
-
-
0035918137
-
A regulatory hydrophobic area in the flexible joint region of plasminogen activator inhibitor-1, defined with fluorescent activity-neutralizing ligands. Ligand-induced serpin polymerization
-
Egelund, R., Einholm, A. P., Pedersen, K. E., Nielsen, R. W., Christensen, A., Deinum, J., and Andreasen, P. A. (2001) A regulatory hydrophobic area in the flexible joint region of plasminogen activator inhibitor-1, defined with fluorescent activity-neutralizing ligands. Ligand-induced serpin polymerization J. Biol. Chem. 276, 13077-13086
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 13077-13086
-
-
Egelund, R.1
Einholm, A.P.2
Pedersen, K.E.3
Nielsen, R.W.4
Christensen, A.5
Deinum, J.6
Andreasen, P.A.7
-
49
-
-
0038266897
-
Plasminogen activator inhibitor-1 polymers, induced by inactivating amphipathic organochemical ligands
-
Pedersen, K. E., Einholm, A. P., Christensen, A., Schack, L., Wind, T., Kenney, J. M., and Andreasen, P. A. (2003) Plasminogen activator inhibitor-1 polymers, induced by inactivating amphipathic organochemical ligands Biochem. J. 372, 747-755
-
(2003)
Biochem. J.
, vol.372
, pp. 747-755
-
-
Pedersen, K.E.1
Einholm, A.P.2
Christensen, A.3
Schack, L.4
Wind, T.5
Kenney, J.M.6
Andreasen, P.A.7
-
50
-
-
33750571151
-
Binding areas of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex for endocytosis receptors of the low-density lipoprotein receptor family, determined by site-directed mutagenesis
-
Skeldal, S., Larsen, J. V., Pedersen, K. E., Petersen, H. H., Egelund, R., Christensen, A., Jensen, J. K., Gliemann, J., and Andreasen, P. A. (2006) Binding areas of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex for endocytosis receptors of the low-density lipoprotein receptor family, determined by site-directed mutagenesis FEBS J. 273, 5143-5159
-
(2006)
FEBS J.
, vol.273
, pp. 5143-5159
-
-
Skeldal, S.1
Larsen, J.V.2
Pedersen, K.E.3
Petersen, H.H.4
Egelund, R.5
Christensen, A.6
Jensen, J.K.7
Gliemann, J.8
Andreasen, P.A.9
-
51
-
-
0032493654
-
2′-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain
-
Ruckman, J., Green, L. S., Beeson, J., Waugh, S., Gillette, W. L., Henninger, D. D., Claesson-Welsh, L., and Janjic, N. (1998) 2′- Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain J. Biol. Chem. 273, 20556-20567
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 20556-20567
-
-
Ruckman, J.1
Green, L.S.2
Beeson, J.3
Waugh, S.4
Gillette, W.L.5
Henninger, D.D.6
Claesson-Welsh, L.7
Janjic, N.8
-
52
-
-
66249126510
-
Antimetastatic potential of PAI-1-specific RNA aptamers
-
Blake, C. M., Sullenger, B. A., Lawrence, D. A., and Fortenberry, Y. M. (2009) Antimetastatic potential of PAI-1-specific RNA aptamers Oligonucleotides 19, 117-128
-
(2009)
Oligonucleotides
, vol.19
, pp. 117-128
-
-
Blake, C.M.1
Sullenger, B.A.2
Lawrence, D.A.3
Fortenberry, Y.M.4
-
53
-
-
0037743532
-
How vitronectin binds PAI-1 to modulate fibrinolysis and cell migration
-
Zhou, A., Huntington, J. A., Pannu, N. S., Carrell, R. W., and Read, R. J. (2003) How vitronectin binds PAI-1 to modulate fibrinolysis and cell migration Nat. Struct. Biol. 10, 541-544
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 541-544
-
-
Zhou, A.1
Huntington, J.A.2
Pannu, N.S.3
Carrell, R.W.4
Read, R.J.5
-
54
-
-
0033580955
-
Accelerated conversion of human plasminogen activator inhibitor-1 to its latent form by antibody binding
-
Verhamme, I., Kvassman, J. O., Day, D., Debrock, S., Vleugels, N., Declerck, P. J., and Shore, J. D. (1999) Accelerated conversion of human plasminogen activator inhibitor-1 to its latent form by antibody binding J. Biol. Chem. 274, 17511-17517
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17511-17517
-
-
Verhamme, I.1
Kvassman, J.O.2
Day, D.3
Debrock, S.4
Vleugels, N.5
Declerck, P.J.6
Shore, J.D.7
-
55
-
-
50449087284
-
A peptide accelerating the conversion of plasminogen activator inhibitor-1 to an inactive latent state
-
Mathiasen, L., Dupont, D. M., Christensen, A., Blouse, G. E., Jensen, J. K., Gils, A., Declerck, P. J., Wind, T., and Andreasen, P. A. (2008) A peptide accelerating the conversion of plasminogen activator inhibitor-1 to an inactive latent state Mol. Pharmacol. 74, 641-653
-
(2008)
Mol. Pharmacol.
, vol.74
, pp. 641-653
-
-
Mathiasen, L.1
Dupont, D.M.2
Christensen, A.3
Blouse, G.E.4
Jensen, J.K.5
Gils, A.6
Declerck, P.J.7
Wind, T.8
Andreasen, P.A.9
-
56
-
-
63849262635
-
Structure, function and antagonists of urokinase-type plasminogen activator
-
Vincenza Carriero, M., Franco, P., Vocca, I., Alfano, D., Longanesi-Cattani, I., Bifulco, K., Mancini, A., Caputi, M., and Stoppelli, M. P. (2009) Structure, function and antagonists of urokinase-type plasminogen activator Front. Biosci. 14, 3782-3794
-
(2009)
Front. Biosci.
, vol.14
, pp. 3782-3794
-
-
Vincenza Carriero, M.1
Franco, P.2
Vocca, I.3
Alfano, D.4
Longanesi-Cattani, I.5
Bifulco, K.6
Mancini, A.7
Caputi, M.8
Stoppelli, M.P.9
-
57
-
-
0023685082
-
Purification and characterization of a plasminogen activator inhibitor 1 binding protein from human plasma. Identification as a multimeric form of S protein (vitronectin)
-
Declerck, P. J., De Mol, M., Alessi, M. C., Baudner, S., Paques, E. P., Preissner, K. T., Muller-Berghaus, G., and Collen, D. (1988) Purification and characterization of a plasminogen activator inhibitor 1 binding protein from human plasma. Identification as a multimeric form of S protein (vitronectin) J. Biol. Chem. 263, 15454-15461
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 15454-15461
-
-
Declerck, P.J.1
De Mol, M.2
Alessi, M.C.3
Baudner, S.4
Paques, E.P.5
Preissner, K.T.6
Muller-Berghaus, G.7
Collen, D.8
-
58
-
-
12544249287
-
Additivity in effects of vitronectin and monoclonal antibodies against α-helix F of plasminogen activator inhibitor-1 on its reactions with target proteinases
-
Komissarov, A. A., Andreasen, P. A., Bodker, J. S., Declerck, P. J., Anagli, J. Y., and Shore, J. D. (2005) Additivity in effects of vitronectin and monoclonal antibodies against α-helix F of plasminogen activator inhibitor-1 on its reactions with target proteinases J. Biol. Chem. 280, 1482-1489
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 1482-1489
-
-
Komissarov, A.A.1
Andreasen, P.A.2
Bodker, J.S.3
Declerck, P.J.4
Anagli, J.Y.5
Shore, J.D.6
-
59
-
-
64349111953
-
Interactions of Plasminogen Activator Inhibitor-1 with Vitronectin Involve an Extensive Binding Surface and Induce Mutual Conformational Rearrangements
-
Blouse, G. E., Dupont, D. M., Schar, C. R., Jensen, J. K., Minor, K. H., Anagli, J. Y., Gardsvoll, H., Ploug, M., Peterson, C. B., and Andreasen, P. A. (2009) Interactions of Plasminogen Activator Inhibitor-1 with Vitronectin Involve an Extensive Binding Surface and Induce Mutual Conformational Rearrangements Biochemistry 48, 1723-1735
-
(2009)
Biochemistry
, vol.48
, pp. 1723-1735
-
-
Blouse, G.E.1
Dupont, D.M.2
Schar, C.R.3
Jensen, J.K.4
Minor, K.H.5
Anagli, J.Y.6
Gardsvoll, H.7
Ploug, M.8
Peterson, C.B.9
Andreasen, P.A.10
-
60
-
-
0033081498
-
The active conformation of plasminogen activator inhibitor 1, a target for drugs to control fibrinolysis and cell adhesion
-
Sharp, A. M., Stein, P. E., Pannu, N. S., Carrell, R. W., Berkenpas, M. B., Ginsburg, D., Lawrence, D. A., and Read, R. J. (1999) The active conformation of plasminogen activator inhibitor 1, a target for drugs to control fibrinolysis and cell adhesion Structure 7, 111-118
-
(1999)
Structure
, vol.7
, pp. 111-118
-
-
Sharp, A.M.1
Stein, P.E.2
Pannu, N.S.3
Carrell, R.W.4
Berkenpas, M.B.5
Ginsburg, D.6
Lawrence, D.A.7
Read, R.J.8
-
61
-
-
52949152789
-
High-resolution structure of the stable plasminogen activator inhibitor type-1 variant 14-1B in its proteinase-cleaved form: A new tool for detailed interaction studies and modeling
-
Jensen, J. K. and Gettins, P. G. (2008) High-resolution structure of the stable plasminogen activator inhibitor type-1 variant 14-1B in its proteinase-cleaved form: a new tool for detailed interaction studies and modeling Protein Sci. 17, 1844-1849
-
(2008)
Protein Sci.
, vol.17
, pp. 1844-1849
-
-
Jensen, J.K.1
Gettins, P.G.2
-
62
-
-
0031962017
-
Binding of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex to the endocytosis receptors α2-macroglobulin receptor/low-density lipoprotein receptor-related protein and very-low-density lipoprotein receptor involves basic residues in the inhibitor
-
Rodenburg, K. W., Kjoller, L., Petersen, H. H., and Andreasen, P. A. (1998) Binding of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex to the endocytosis receptors α2-macroglobulin receptor/low-density lipoprotein receptor-related protein and very-low-density lipoprotein receptor involves basic residues in the inhibitor Biochem. J. 329 (Part 1) 55-63
-
(1998)
Biochem. J.
, vol.329
, Issue.PART 1
, pp. 55-63
-
-
Rodenburg, K.W.1
Kjoller, L.2
Petersen, H.H.3
Andreasen, P.A.4
-
63
-
-
0031743824
-
Plasminogen activator inhibitor 1 contains a cryptic high affinity receptor binding site that is exposed upon complex formation with tissue-type plasminogen activator
-
Horn, I. R., van den Berg, B. M., Moestrup, S. K., Pannekoek, H., and van Zonneveld, A. J. (1998) Plasminogen activator inhibitor 1 contains a cryptic high affinity receptor binding site that is exposed upon complex formation with tissue-type plasminogen activator Thromb. Haemostasis 80, 822-828
-
(1998)
Thromb. Haemostasis
, vol.80
, pp. 822-828
-
-
Horn, I.R.1
Van Den Berg, B.M.2
Moestrup, S.K.3
Pannekoek, H.4
Van Zonneveld, A.J.5
-
64
-
-
33750559320
-
Inhibition of plasminogen activator inhibitor-1 binding to endocytosis receptors of the low-density-lipoprotein receptor family by a peptide isolated from a phage display library
-
Jensen, J. K., Malmendal, A., Schiott, B., Skeldal, S., Pedersen, K. E., Celik, L., Nielsen, N. C., Andreasen, P. A., and Wind, T. (2006) Inhibition of plasminogen activator inhibitor-1 binding to endocytosis receptors of the low-density-lipoprotein receptor family by a peptide isolated from a phage display library Biochem. J. 399, 387-396
-
(2006)
Biochem. J.
, vol.399
, pp. 387-396
-
-
Jensen, J.K.1
Malmendal, A.2
Schiott, B.3
Skeldal, S.4
Pedersen, K.E.5
Celik, L.6
Nielsen, N.C.7
Andreasen, P.A.8
Wind, T.9
-
65
-
-
0042466527
-
Biochemical importance of glycosylation of plasminogen activator inhibitor-1
-
Gils, A., Pedersen, K. E., Skottrup, P., Christensen, A., Naessens, D., Deinum, J., Enghild, J. J., Declerck, P. J., and Andreasen, P. A. (2003) Biochemical importance of glycosylation of plasminogen activator inhibitor-1 Thromb. Haemostasis 90, 206-217
-
(2003)
Thromb. Haemostasis
, vol.90
, pp. 206-217
-
-
Gils, A.1
Pedersen, K.E.2
Skottrup, P.3
Christensen, A.4
Naessens, D.5
Deinum, J.6
Enghild, J.J.7
Declerck, P.J.8
Andreasen, P.A.9
-
66
-
-
1642318429
-
The structural basis for the pathophysiological relevance of PAI-1 in cardiovascular diseases and the development of potential PAI-1 inhibitors
-
Gils, A. and Declerck, P. J. (2004) The structural basis for the pathophysiological relevance of PAI-I in cardiovascular diseases and the development of potential PAI-I inhibitors Thromb. Haemostasis 91, 425-437 (Pubitemid 38396864)
-
(2004)
Thrombosis and Haemostasis
, vol.91
, Issue.3
, pp. 425-437
-
-
Gils, A.1
Declerck, P.J.2
|