Polyetheylenimine-polyplexes of Spiegelmer NOX-A50 directed against intracellular high mobility group protein A1 (HMGA1) reduce tumor growth in vivo

Journal of Biological Chemistry

Volumn 285, Issue 51, 2010, Pages 40012-40018

  Maasch, Christian ^a   Vater, Axel ^a   Buchner, Klaus ^a   Purschke, Werner G ^a   Eulberg, Dirk ^a   Vonhoff, Stefan ^a   Klussmann, Sven ^a  

^a NOXXON PHARMA AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BELONG TO; BINDING PARTNERS; DOUBLE STRANDED DNA; EPITHELIAL-MESENCHYMAL TRANSITION; HIGH MOBILITY GROUP PROTEINS; HIGH-MOBILITY-GROUP A1 PROTEINS; HUMAN MALIGNANCIES; IN-VITRO; IN-VIVO; NANOMOLAR AFFINITY; PANCREATIC ADENOCARCINOMA; PANCREATIC CANCERS; POLYETHYLENIMINES; POLYPLEXES; THERAPEUTIC TARGETS; TISSUE DISTRIBUTIONS; TUMOR GROWTH; TUMOR VOLUMES;

CELL CULTURE; OLIGONUCLEOTIDES; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; RNA; TRANSCRIPTION FACTORS;

TUMORS;

ANTINEOPLASTIC AGENT; DOUBLE STRANDED DNA; HIGH MOBILITY GROUP A1A PROTEIN; HIGH MOBILITY GROUP A1B PROTEIN; MACROGOL; NOX A 50; NOX F 33; OLIGONUCLEOTIDE; POLYETHYLENEIMINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG PROTEIN BINDING; DRUG TARGETING; DRUG TISSUE LEVEL; HUMAN; HUMAN CELL; IN VITRO SELECTION; MOUSE; NONHUMAN; PANCREAS CANCER; PRIORITY JOURNAL; TUMOR XENOGRAFT;

ADENOCARCINOMA; ANIMALS; APTAMERS, NUCLEOTIDE; CELL LINE, TUMOR; DNA, NEOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; HMGA PROTEINS; HUMANS; MICE; MICE, MUTANT STRAINS; PANCREATIC NEOPLASMS; PROTEIN BINDING; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS;

EID: 78650072690     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.178533     Document Type: Article

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