A new paradigm for aptamer therapeutic AS1411 action: Uptake by macropinocytosis and its stimulation by a nucleolin-dependent mechanism

Cancer Research

Volumn 70, Issue 21, 2010, Pages 8617-8629

  Reyes Reyes, E Merit ^a   Teng, Yun ^a   Bates, Paula J ^a,b  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; APTAMER; AS 1411; NUCLEOLIN; OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

ARTICLE; BIOTINYLATION; CANCER CELL; CELL TYPE; CONTROLLED STUDY; DENSITOMETRY; DRUG MECHANISM; ENDOCYTOSIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; MALE; PINOCYTOSIS; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN PURIFICATION; RNA INTERFERENCE; SKIN FIBROBLAST;

ANTINEOPLASTIC AGENTS; APTAMERS, NUCLEOTIDE; BLOTTING, WESTERN; BREAST; BREAST NEOPLASMS; CELLS, CULTURED; DRUG DELIVERY SYSTEMS; FEMALE; FIBROBLASTS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MALE; OLIGODEOXYRIBONUCLEOTIDES; PHOSPHOPROTEINS; PINOCYTOSIS; PROSTATIC NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; SKIN;

EID: 78449269097     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-0920     Document Type: Article

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