-
1
-
-
77958109197
-
Mechanisms of trinucleotide repeat instability during human development
-
McMurray C.T. Mechanisms of trinucleotide repeat instability during human development. Nat. Rev. Genet. 2010, 11(11):786-799.
-
(2010)
Nat. Rev. Genet.
, vol.11
, Issue.11
, pp. 786-799
-
-
McMurray, C.T.1
-
2
-
-
77949775195
-
Repeat expansion disease: progress and puzzles in disease pathogenesis
-
La Spada A.R., Taylor J.P. Repeat expansion disease: progress and puzzles in disease pathogenesis. Nat. Rev. Genet. 2010, 11(4):247-258.
-
(2010)
Nat. Rev. Genet.
, vol.11
, Issue.4
, pp. 247-258
-
-
La Spada, A.R.1
Taylor, J.P.2
-
3
-
-
67649983121
-
Instability and chromatin structure of expanded trinucleotide repeats
-
Dion V., Wilson J.H. Instability and chromatin structure of expanded trinucleotide repeats. Trends Genet. 2009, 25(7):288-297.
-
(2009)
Trends Genet.
, vol.25
, Issue.7
, pp. 288-297
-
-
Dion, V.1
Wilson, J.H.2
-
4
-
-
65549134765
-
Pathogenic mechanisms of a polyglutamine-mediated neurodegenerative disease, spinocerebellar ataxia type 1
-
Zoghbi H.Y., Orr H.T. Pathogenic mechanisms of a polyglutamine-mediated neurodegenerative disease, spinocerebellar ataxia type 1. J. Biol. Chem. 2009, 284(12):7425-7429.
-
(2009)
J. Biol. Chem.
, vol.284
, Issue.12
, pp. 7425-7429
-
-
Zoghbi, H.Y.1
Orr, H.T.2
-
5
-
-
44449131447
-
Huntington's disease: from pathology and genetics to potential therapies
-
Imarisio S., et al. Huntington's disease: from pathology and genetics to potential therapies. Biochem. J. 2008, 412(2):191-209.
-
(2008)
Biochem. J.
, vol.412
, Issue.2
, pp. 191-209
-
-
Imarisio, S.1
-
6
-
-
67349104211
-
Molecular mechanisms underlying polyalanine diseases
-
Messaed C., Rouleau G.A. Molecular mechanisms underlying polyalanine diseases. Neurobiol. Dis. 2009, 34(3):397-405.
-
(2009)
Neurobiol. Dis.
, vol.34
, Issue.3
, pp. 397-405
-
-
Messaed, C.1
Rouleau, G.A.2
-
7
-
-
0347135948
-
An abundance of bidirectional promoters in the human genome
-
Trinklein N.D., et al. An abundance of bidirectional promoters in the human genome. Genome Res. 2004, 14(1):62-66.
-
(2004)
Genome Res.
, vol.14
, Issue.1
, pp. 62-66
-
-
Trinklein, N.D.1
-
8
-
-
57849105533
-
The antisense transcriptomes of human cells
-
He Y., et al. The antisense transcriptomes of human cells. Science 2008, 322(5909):1855-1857.
-
(2008)
Science
, vol.322
, Issue.5909
, pp. 1855-1857
-
-
He, Y.1
-
9
-
-
61449238441
-
Bidirectional expression of the SCA8 expansion mutation: one mutation, two genes
-
Ikeda Y., Daughters R.S., Ranum L.P. Bidirectional expression of the SCA8 expansion mutation: one mutation, two genes. Cerebellum 2008, 7(2):150-158.
-
(2008)
Cerebellum
, vol.7
, Issue.2
, pp. 150-158
-
-
Ikeda, Y.1
Daughters, R.S.2
Ranum, L.P.3
-
10
-
-
77953887860
-
Partners in crime: bidirectional transcription in unstable microsatellite disease
-
Batra R., Charizanis K., Swanson M.S. Partners in crime: bidirectional transcription in unstable microsatellite disease. Hum. Mol. Genet. 2010, 19(R1):R77-R82.
-
(2010)
Hum. Mol. Genet.
, vol.19
, Issue.R1
-
-
Batra, R.1
Charizanis, K.2
Swanson, M.S.3
-
11
-
-
78651099242
-
Bidirectional transcription stimulates expansion and contraction of expanded (CTG)*(CAG) repeats
-
Nakamori M., Pearson C.E., Thornton C.A. Bidirectional transcription stimulates expansion and contraction of expanded (CTG)*(CAG) repeats. Hum. Mol. Genet. 2011, 20(3):580-588.
-
(2011)
Hum. Mol. Genet.
, vol.20
, Issue.3
, pp. 580-588
-
-
Nakamori, M.1
Pearson, C.E.2
Thornton, C.A.3
-
12
-
-
78651105614
-
Non-ATG-initiated translation directed by microsatellite expansions
-
Zu T., et al. Non-ATG-initiated translation directed by microsatellite expansions. Proc. Natl. Acad. Sci. U.S.A. 2011, 108(1):260-265.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, Issue.1
, pp. 260-265
-
-
Zu, T.1
-
13
-
-
79953745706
-
Repeat associated non-ATG translation initiation: one DNA, two transcripts, seven reading frames, potentially nine toxic entities!
-
Pearson C.E. Repeat associated non-ATG translation initiation: one DNA, two transcripts, seven reading frames, potentially nine toxic entities!. PLoS Genet. 2011, 7(3):e1002018.
-
(2011)
PLoS Genet.
, vol.7
, Issue.3
-
-
Pearson, C.E.1
-
14
-
-
27644525713
-
Antisense transcription and heterochromatin at the DM1 CTG repeats are constrained by CTCF
-
Cho D.H., et al. Antisense transcription and heterochromatin at the DM1 CTG repeats are constrained by CTCF. Mol. Cell 2005, 20(3):483-489.
-
(2005)
Mol. Cell
, vol.20
, Issue.3
, pp. 483-489
-
-
Cho, D.H.1
-
15
-
-
79955660764
-
An antisense CAG repeat transcript at JPH3 locus mediates expanded polyglutamine protein toxicity in Huntington's disease-like 2 mice
-
Wilburn B., et al. An antisense CAG repeat transcript at JPH3 locus mediates expanded polyglutamine protein toxicity in Huntington's disease-like 2 mice. Neuron 2011, 70(3):427-440.
-
(2011)
Neuron
, vol.70
, Issue.3
, pp. 427-440
-
-
Wilburn, B.1
-
16
-
-
36248967098
-
An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individuals
-
Ladd P.D., et al. An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individuals. Hum. Mol. Genet. 2007, 16(24):3174-3187.
-
(2007)
Hum. Mol. Genet.
, vol.16
, Issue.24
, pp. 3174-3187
-
-
Ladd, P.D.1
-
17
-
-
80051695536
-
A natural antisense transcript at the Huntington's disease repeat locus regulates HTT expression
-
Chung D.W., et al. A natural antisense transcript at the Huntington's disease repeat locus regulates HTT expression. Hum. Mol. Genet. 2011, 20(17):3467-3477.
-
(2011)
Hum. Mol. Genet.
, vol.20
, Issue.17
, pp. 3467-3477
-
-
Chung, D.W.1
-
18
-
-
79959306523
-
CTCF regulates ataxin-7 expression through promotion of a convergently transcribed, antisense noncoding RNA
-
Sopher B.L., et al. CTCF regulates ataxin-7 expression through promotion of a convergently transcribed, antisense noncoding RNA. Neuron 2011, 70(6):1071-1084.
-
(2011)
Neuron
, vol.70
, Issue.6
, pp. 1071-1084
-
-
Sopher, B.L.1
-
19
-
-
79959937861
-
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
-
Cortellino S., et al. Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell 2011, 146(1):67-79.
-
(2011)
Cell
, vol.146
, Issue.1
, pp. 67-79
-
-
Cortellino, S.1
-
20
-
-
79951810964
-
Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability
-
Cortazar D., et al. Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability. Nature 2011, 470(7334):419-423.
-
(2011)
Nature
, vol.470
, Issue.7334
, pp. 419-423
-
-
Cortazar, D.1
-
21
-
-
77950443318
-
NER factors are recruited to active promoters and facilitate chromatin modification for transcription in the absence of exogenous genotoxic attack
-
Le May N., et al. NER factors are recruited to active promoters and facilitate chromatin modification for transcription in the absence of exogenous genotoxic attack. Mol. Cell 2010, 38(1):54-66.
-
(2010)
Mol. Cell
, vol.38
, Issue.1
, pp. 54-66
-
-
Le May, N.1
-
22
-
-
0035896610
-
RNA CUG repeats sequester CUGBP1 and alter protein levels and activity of CUGBP1
-
Timchenko N.A., et al. RNA CUG repeats sequester CUGBP1 and alter protein levels and activity of CUGBP1. J. Biol. Chem. 2001, 276(11):7820-7826.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.11
, pp. 7820-7826
-
-
Timchenko, N.A.1
-
23
-
-
33745288299
-
MBNL1 and CUGBP1 modify expanded CUG-induced toxicity in a Drosophila model of myotonic dystrophy type 1
-
de Haro M., et al. MBNL1 and CUGBP1 modify expanded CUG-induced toxicity in a Drosophila model of myotonic dystrophy type 1. Hum. Mol. Genet. 2006, 15(13):2138-2145.
-
(2006)
Hum. Mol. Genet.
, vol.15
, Issue.13
, pp. 2138-2145
-
-
de Haro, M.1
-
24
-
-
33644858553
-
The Muscleblind family of proteins: an emerging class of regulators of developmentally programmed alternative splicing
-
Pascual M., et al. The Muscleblind family of proteins: an emerging class of regulators of developmentally programmed alternative splicing. Differentiation 2006, 74(2/3):65-80.
-
(2006)
Differentiation
, vol.74
, Issue.2-3
, pp. 65-80
-
-
Pascual, M.1
-
25
-
-
71049162902
-
MBNL and CELF proteins regulate alternative splicing of the skeletal muscle chloride channel CLCN1
-
Kino Y., et al. MBNL and CELF proteins regulate alternative splicing of the skeletal muscle chloride channel CLCN1. Nucleic Acids Res. 2009, 37(19):6477-6490.
-
(2009)
Nucleic Acids Res.
, vol.37
, Issue.19
, pp. 6477-6490
-
-
Kino, Y.1
-
26
-
-
76249102027
-
Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy
-
Du H., et al. Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy. Nat. Struct. Mol. Biol. 2010, 17(2):187-193.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, Issue.2
, pp. 187-193
-
-
Du, H.1
-
27
-
-
84863275756
-
Muscleblind-like 1 knockout mice reveal novel splicing defects in the myotonic dystrophy brain
-
Suenaga K., et al. Muscleblind-like 1 knockout mice reveal novel splicing defects in the myotonic dystrophy brain. PLoS ONE 2012, 7(3):e33218.
-
(2012)
PLoS ONE
, vol.7
, Issue.3
-
-
Suenaga, K.1
-
28
-
-
65949106802
-
Molecular effects of the CTG repeats in mutant Dystrophia Myotonica protein kinase gene
-
Llamusi B., Artero R. Molecular effects of the CTG repeats in mutant Dystrophia Myotonica protein kinase gene. Curr. Genomics 2008, 9(8):509-516.
-
(2008)
Curr. Genomics
, vol.9
, Issue.8
, pp. 509-516
-
-
Llamusi, B.1
Artero, R.2
-
30
-
-
34548039992
-
Huntington's disease like-2 neuropathology
-
Greenstein P.E., et al. Huntington's disease like-2 neuropathology. Mov. Disord. 2007, 22(10):1416-1423.
-
(2007)
Mov. Disord.
, vol.22
, Issue.10
, pp. 1416-1423
-
-
Greenstein, P.E.1
-
31
-
-
41949137715
-
A comparison of huntington disease and huntington disease-like 2 neuropathology
-
Rudnicki D.D., et al. A comparison of huntington disease and huntington disease-like 2 neuropathology. J. Neuropathol. Exp. Neurol. 2008, 67(4):366-374.
-
(2008)
J. Neuropathol. Exp. Neurol.
, vol.67
, Issue.4
, pp. 366-374
-
-
Rudnicki, D.D.1
-
32
-
-
18344379670
-
A repeat expansion in the gene encoding junctophilin-3 is associated with Huntington disease-like 2
-
Holmes S.E., et al. A repeat expansion in the gene encoding junctophilin-3 is associated with Huntington disease-like 2. Nat. Genet. 2001, 29(4):377-378.
-
(2001)
Nat. Genet.
, vol.29
, Issue.4
, pp. 377-378
-
-
Holmes, S.E.1
-
33
-
-
0032900772
-
An untranslated CTG expansion causes a novel form of spinocerebellar ataxia (SCA8)
-
Koob M.D., et al. An untranslated CTG expansion causes a novel form of spinocerebellar ataxia (SCA8). Nat. Genet. 1999, 21(4):379-384.
-
(1999)
Nat. Genet.
, vol.21
, Issue.4
, pp. 379-384
-
-
Koob, M.D.1
-
34
-
-
33745545413
-
Bidirectional expression of CUG and CAG expansion transcripts and intranuclear polyglutamine inclusions in spinocerebellar ataxia type 8
-
Moseley M.L., et al. Bidirectional expression of CUG and CAG expansion transcripts and intranuclear polyglutamine inclusions in spinocerebellar ataxia type 8. Nat. Genet. 2006, 38(7):758-769.
-
(2006)
Nat. Genet.
, vol.38
, Issue.7
, pp. 758-769
-
-
Moseley, M.L.1
-
35
-
-
1542380523
-
The spinocerebellar ataxia 8 noncoding RNA causes neurodegeneration and associates with staufen in Drosophila
-
Mutsuddi M., et al. The spinocerebellar ataxia 8 noncoding RNA causes neurodegeneration and associates with staufen in Drosophila. Curr. Biol. 2004, 14(4):302-308.
-
(2004)
Curr. Biol.
, vol.14
, Issue.4
, pp. 302-308
-
-
Mutsuddi, M.1
-
36
-
-
70149112363
-
RNA gain-of-function in spinocerebellar ataxia type 8
-
Daughters R.S., et al. RNA gain-of-function in spinocerebellar ataxia type 8. PLoS Genet. 2009, 5(8):e1000600.
-
(2009)
PLoS Genet.
, vol.5
, Issue.8
-
-
Daughters, R.S.1
-
37
-
-
33749170168
-
Targeted deletion of a single Sca8 ataxia locus allele in mice causes abnormal gait, progressive loss of motor coordination, and Purkinje cell dendritic deficits
-
He Y., et al. Targeted deletion of a single Sca8 ataxia locus allele in mice causes abnormal gait, progressive loss of motor coordination, and Purkinje cell dendritic deficits. J. Neurosci. 2006, 26(39):9975-9982.
-
(2006)
J. Neurosci.
, vol.26
, Issue.39
, pp. 9975-9982
-
-
He, Y.1
-
38
-
-
83555164884
-
Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila
-
Cernilogar F.M., et al. Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila. Nature 2011, 480(7377):391-395.
-
(2011)
Nature
, vol.480
, Issue.7377
, pp. 391-395
-
-
Cernilogar, F.M.1
-
39
-
-
79953762028
-
Triplet repeat-derived siRNAs enhance RNA-mediated toxicity in a Drosophila model for myotonic dystrophy
-
Yu Z., Teng X., Bonini N.M. Triplet repeat-derived siRNAs enhance RNA-mediated toxicity in a Drosophila model for myotonic dystrophy. PLoS Genet. 2011, 7(3):e1001340.
-
(2011)
PLoS Genet.
, vol.7
, Issue.3
-
-
Yu, Z.1
Teng, X.2
Bonini, N.M.3
-
40
-
-
0034282958
-
Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy
-
Miller J.W., et al. Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy. EMBO J. 2000, 19(17):4439-4448.
-
(2000)
EMBO J.
, vol.19
, Issue.17
, pp. 4439-4448
-
-
Miller, J.W.1
-
41
-
-
0034935016
-
CTCF-binding sites flank CTG/CAG repeats and form a methylation-sensitive insulator at the DM1 locus
-
Filippova G.N., et al. CTCF-binding sites flank CTG/CAG repeats and form a methylation-sensitive insulator at the DM1 locus. Nat. Genet. 2001, 28(4):335-343.
-
(2001)
Nat. Genet.
, vol.28
, Issue.4
, pp. 335-343
-
-
Filippova, G.N.1
-
42
-
-
0026566108
-
Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3' end of a transcript encoding a protein kinase family member
-
Brook J.D., et al. Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3' end of a transcript encoding a protein kinase family member. Cell 1992, 68(4):799-808.
-
(1992)
Cell
, vol.68
, Issue.4
, pp. 799-808
-
-
Brook, J.D.1
-
43
-
-
0026773612
-
Physical and genetic characterization of the distal segment of the myotonic dystrophy area on 19q
-
Jansen G., et al. Physical and genetic characterization of the distal segment of the myotonic dystrophy area on 19q. Genomics 1992, 13(3):509-517.
-
(1992)
Genomics
, vol.13
, Issue.3
, pp. 509-517
-
-
Jansen, G.1
-
44
-
-
0026603841
-
Myotonic dystrophy mutation: an unstable CTG repeat in the 3'untranslated region of the gene
-
Mahadevan M., et al. Myotonic dystrophy mutation: an unstable CTG repeat in the 3'untranslated region of the gene. Science 1992, 255(5049):1253-1255.
-
(1992)
Science
, vol.255
, Issue.5049
, pp. 1253-1255
-
-
Mahadevan, M.1
-
45
-
-
34948839944
-
Facultative heterochromatin: is there a distinctive molecular signature?
-
Trojer P., Reinberg D. Facultative heterochromatin: is there a distinctive molecular signature?. Mol. Cell 2007, 28(1):1-13.
-
(2007)
Mol. Cell
, vol.28
, Issue.1
, pp. 1-13
-
-
Trojer, P.1
Reinberg, D.2
-
46
-
-
79960484375
-
Gene silencing in X-chromosome inactivation: advances in understanding facultative heterochromatin formation
-
Wutz A. Gene silencing in X-chromosome inactivation: advances in understanding facultative heterochromatin formation. Nat. Rev. Genet. 2011, 12(8):542-553.
-
(2011)
Nat. Rev. Genet.
, vol.12
, Issue.8
, pp. 542-553
-
-
Wutz, A.1
-
47
-
-
73049159343
-
Correlations between sex chromatin and sex chromosomes
-
Barr M.L., Carr D.H. Correlations between sex chromatin and sex chromosomes. Acta Cytol. 1962, 6:34-45.
-
(1962)
Acta Cytol.
, vol.6
, pp. 34-45
-
-
Barr, M.L.1
Carr, D.H.2
-
48
-
-
0022544604
-
The relative intranuclear positions of Barr bodies in XXX non-transformed human fibroblasts
-
Belmont A.S., Bignone F., Ts'o P.O. The relative intranuclear positions of Barr bodies in XXX non-transformed human fibroblasts. Exp. Cell Res. 1986, 165(1):165-179.
-
(1986)
Exp. Cell Res.
, vol.165
, Issue.1
, pp. 165-179
-
-
Belmont, A.S.1
Bignone, F.2
Ts'o, P.O.3
-
49
-
-
0029742502
-
DNA exposure and condensation in the X and 21 chromosomes
-
Puck T.T., Johnson R. DNA exposure and condensation in the X and 21 chromosomes. Stem Cells 1996, 14(5):548-557.
-
(1996)
Stem Cells
, vol.14
, Issue.5
, pp. 548-557
-
-
Puck, T.T.1
Johnson, R.2
-
50
-
-
80052423475
-
XIST RNA and architecture of the inactive X chromosome: implications for the repeat genome
-
Hall L.L., Lawrence J.B. XIST RNA and architecture of the inactive X chromosome: implications for the repeat genome. Cold Spring Harb. Symp. Quant. Biol. 2010, 75:345-356.
-
(2010)
Cold Spring Harb. Symp. Quant. Biol.
, vol.75
, pp. 345-356
-
-
Hall, L.L.1
Lawrence, J.B.2
-
51
-
-
84867163018
-
Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations
-
Pinter S.F., et al. Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations. Genome Res. 2012, 22:1864-1876.
-
(2012)
Genome Res.
, vol.22
, pp. 1864-1876
-
-
Pinter, S.F.1
-
52
-
-
79961028059
-
Xist regulation and function explored
-
Pontier D.B., Gribnau J. Xist regulation and function explored. Hum. Genet. 2011, 130(2):223-236.
-
(2011)
Hum. Genet.
, vol.130
, Issue.2
, pp. 223-236
-
-
Pontier, D.B.1
Gribnau, J.2
-
53
-
-
0344442391
-
The fragile X syndrome repeats form RNA hairpins that do not activate the interferon-inducible protein kinase, PKR, but are cut by Dicer
-
Handa V., Saha T., Usdin K. The fragile X syndrome repeats form RNA hairpins that do not activate the interferon-inducible protein kinase, PKR, but are cut by Dicer. Nucleic Acids Res. 2003, 31(21):6243-6248.
-
(2003)
Nucleic Acids Res.
, vol.31
, Issue.21
, pp. 6243-6248
-
-
Handa, V.1
Saha, T.2
Usdin, K.3
-
54
-
-
33745615104
-
First in vivo evidence of microRNA-induced fragile X mental retardation syndrome
-
Lin S.L., Chang S.J., Ying S.Y. First in vivo evidence of microRNA-induced fragile X mental retardation syndrome. Mol. Psychiatry 2006, 11(7):616-617.
-
(2006)
Mol. Psychiatry
, vol.11
, Issue.7
, pp. 616-617
-
-
Lin, S.L.1
Chang, S.J.2
Ying, S.Y.3
-
55
-
-
33847077134
-
Ribonuclease dicer cleaves triplet repeat hairpins into shorter repeats that silence specific targets
-
Krol J., et al. Ribonuclease dicer cleaves triplet repeat hairpins into shorter repeats that silence specific targets. Mol. Cell 2007, 25(4):575-586.
-
(2007)
Mol. Cell
, vol.25
, Issue.4
, pp. 575-586
-
-
Krol, J.1
-
57
-
-
38449116843
-
Intron-mediated RNA interference and microRNA (miRNA)
-
Lin S.L., Kim H., Ying S.Y. Intron-mediated RNA interference and microRNA (miRNA). Front. Biosci. 2008, 13:2216-2230.
-
(2008)
Front. Biosci.
, vol.13
, pp. 2216-2230
-
-
Lin, S.L.1
Kim, H.2
Ying, S.Y.3
-
58
-
-
0141534299
-
A novel RNA splicing-mediated gene silencing mechanism potential for genome evolution
-
Lin S.L., et al. A novel RNA splicing-mediated gene silencing mechanism potential for genome evolution. Biochem. Biophys. Res. Commun. 2003, 310(3):754-760.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.310
, Issue.3
, pp. 754-760
-
-
Lin, S.L.1
-
59
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116(2):281-297.
-
(2004)
Cell
, vol.116
, Issue.2
, pp. 281-297
-
-
Bartel, D.P.1
-
60
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
-
Yi R., et al. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 2003, 17(24):3011-3016.
-
(2003)
Genes Dev.
, vol.17
, Issue.24
, pp. 3011-3016
-
-
Yi, R.1
-
61
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund E., et al. Nuclear export of microRNA precursors. Science 2004, 303(5654):95-98.
-
(2004)
Science
, vol.303
, Issue.5654
, pp. 95-98
-
-
Lund, E.1
-
62
-
-
23844530681
-
Asymmetry of intronic pre-miRNA structures in functional RISC assembly
-
Lin S.L., Chang D., Ying S.Y. Asymmetry of intronic pre-miRNA structures in functional RISC assembly. Gene 2005, 356:32-38.
-
(2005)
Gene
, vol.356
, pp. 32-38
-
-
Lin, S.L.1
Chang, D.2
Ying, S.Y.3
-
63
-
-
78650306521
-
Small RNA sorting: matchmaking for Argonautes
-
Czech B., Hannon G.J. Small RNA sorting: matchmaking for Argonautes. Nat. Rev. Genet. 2011, 12(1):19-31.
-
(2011)
Nat. Rev. Genet.
, vol.12
, Issue.1
, pp. 19-31
-
-
Czech, B.1
Hannon, G.J.2
-
64
-
-
82955231555
-
RITS-connecting transcription, RNA interference, and heterochromatin assembly in fission yeast
-
Creamer K.M., Partridge J.F. RITS-connecting transcription, RNA interference, and heterochromatin assembly in fission yeast. Wiley Interdiscip. Rev. RNA 2011, 2(5):632-646.
-
(2011)
Wiley Interdiscip. Rev. RNA
, vol.2
, Issue.5
, pp. 632-646
-
-
Creamer, K.M.1
Partridge, J.F.2
-
65
-
-
10744225153
-
Asymmetry in the assembly of the RNAi enzyme complex
-
Schwarz D.S., et al. Asymmetry in the assembly of the RNAi enzyme complex. Cell 2003, 115(2):199-208.
-
(2003)
Cell
, vol.115
, Issue.2
, pp. 199-208
-
-
Schwarz, D.S.1
-
66
-
-
0142165224
-
Functional siRNAs and miRNAs exhibit strand bias
-
Khvorova A., Reynolds A., Jayasena S.D. Functional siRNAs and miRNAs exhibit strand bias. Cell 2003, 115(2):209-216.
-
(2003)
Cell
, vol.115
, Issue.2
, pp. 209-216
-
-
Khvorova, A.1
Reynolds, A.2
Jayasena, S.D.3
-
67
-
-
23044437498
-
RNA meets chromatin
-
Bernstein E., Allis C.D. RNA meets chromatin. Genes Dev. 2005, 19(14):1635-1655.
-
(2005)
Genes Dev.
, vol.19
, Issue.14
, pp. 1635-1655
-
-
Bernstein, E.1
Allis, C.D.2
-
68
-
-
4544242851
-
Induction of DNA methylation and gene silencing by short interfering RNAs in human cells
-
Kawasaki H., Taira K. Induction of DNA methylation and gene silencing by short interfering RNAs in human cells. Nature 2004, 431(7005):211-217.
-
(2004)
Nature
, vol.431
, Issue.7005
, pp. 211-217
-
-
Kawasaki, H.1
Taira, K.2
-
69
-
-
4344705410
-
Small interfering RNA-induced transcriptional gene silencing in human cells
-
Morris K.V., et al. Small interfering RNA-induced transcriptional gene silencing in human cells. Science 2004, 305(5688):1289-1292.
-
(2004)
Science
, vol.305
, Issue.5688
, pp. 1289-1292
-
-
Morris, K.V.1
-
70
-
-
0029943141
-
Perturbation of nuclear architecture by long-distance chromosome interactions
-
Dernburg A.F., et al. Perturbation of nuclear architecture by long-distance chromosome interactions. Cell 1996, 85(5):745-759.
-
(1996)
Cell
, vol.85
, Issue.5
, pp. 745-759
-
-
Dernburg, A.F.1
-
71
-
-
84860548726
-
Mating-type genes and MAT switching in Saccharomyces cerevisiae
-
Haber J.E. Mating-type genes and MAT switching in Saccharomyces cerevisiae. Genetics 2012, 191(1):33-64.
-
(2012)
Genetics
, vol.191
, Issue.1
, pp. 33-64
-
-
Haber, J.E.1
-
72
-
-
0037058955
-
The insulation of genes from external enhancers and silencing chromatin
-
Burgess-Beusse B., et al. The insulation of genes from external enhancers and silencing chromatin. Proc. Natl. Acad. Sci. U.S.A. 2002, 99(Suppl. 4):16433-16437.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, Issue.SUPPL. 4
, pp. 16433-16437
-
-
Burgess-Beusse, B.1
-
73
-
-
0029059218
-
Triplet repeat expansion in myotonic dystrophy alters the adjacent chromatin structure
-
Otten A.D., Tapscott S.J. Triplet repeat expansion in myotonic dystrophy alters the adjacent chromatin structure. Proc. Natl. Acad. Sci. U.S.A. 1995, 92(12):5465-5469.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, Issue.12
, pp. 5465-5469
-
-
Otten, A.D.1
Tapscott, S.J.2
-
74
-
-
0032076126
-
Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy
-
Philips A.V., Timchenko L.T., Cooper T.A. Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy. Science 1998, 280(5364):737-741.
-
(1998)
Science
, vol.280
, Issue.5364
, pp. 737-741
-
-
Philips, A.V.1
Timchenko, L.T.2
Cooper, T.A.3
-
75
-
-
78149272981
-
The distribution of repressive histone modifications on silenced FMR1 alleles provides clues to the mechanism of gene silencing in fragile X syndrome
-
Kumari D., Usdin K. The distribution of repressive histone modifications on silenced FMR1 alleles provides clues to the mechanism of gene silencing in fragile X syndrome. Hum. Mol. Genet. 2010, 19(23):4634-4642.
-
(2010)
Hum. Mol. Genet.
, vol.19
, Issue.23
, pp. 4634-4642
-
-
Kumari, D.1
Usdin, K.2
-
76
-
-
27944486578
-
Gene activation and deactivation related changes in the three-dimensional structure of chromatin
-
Wegel E., Shaw P. Gene activation and deactivation related changes in the three-dimensional structure of chromatin. Chromosoma 2005, 114(5):331-337.
-
(2005)
Chromosoma
, vol.114
, Issue.5
, pp. 331-337
-
-
Wegel, E.1
Shaw, P.2
-
77
-
-
33646849431
-
The relationship between higher-order chromatin structure and transcription
-
Gilbert N., Bickmore W.A. The relationship between higher-order chromatin structure and transcription. Biochem. Soc. Symp. 2006, (73):59-66.
-
(2006)
Biochem. Soc. Symp.
, Issue.73
, pp. 59-66
-
-
Gilbert, N.1
Bickmore, W.A.2
-
78
-
-
4444258534
-
Chromatin architecture of the human genome: gene-rich domains are enriched in open chromatin fibers
-
Gilbert N., et al. Chromatin architecture of the human genome: gene-rich domains are enriched in open chromatin fibers. Cell 2004, 118(5):555-566.
-
(2004)
Cell
, vol.118
, Issue.5
, pp. 555-566
-
-
Gilbert, N.1
-
79
-
-
65849122227
-
Molecular pathogenesis and cellular pathology of spinocerebellar ataxia type 7 neurodegeneration
-
Garden G.A., La Spada A.R. Molecular pathogenesis and cellular pathology of spinocerebellar ataxia type 7 neurodegeneration. Cerebellum 2008, 7(2):138-149.
-
(2008)
Cerebellum
, vol.7
, Issue.2
, pp. 138-149
-
-
Garden, G.A.1
La Spada, A.R.2
-
80
-
-
57149089871
-
CTCF cis-regulates trinucleotide repeat instability in an epigenetic manner: a novel basis for mutational hot spot determination
-
Libby R.T., et al. CTCF cis-regulates trinucleotide repeat instability in an epigenetic manner: a novel basis for mutational hot spot determination. PLoS Genet. 2008, 4(11):e1000257.
-
(2008)
PLoS Genet.
, vol.4
, Issue.11
-
-
Libby, R.T.1
-
81
-
-
34249337762
-
OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells
-
Kovtun I.V., et al. OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells. Nature 2007, 447(7143):447-452.
-
(2007)
Nature
, vol.447
, Issue.7143
, pp. 447-452
-
-
Kovtun, I.V.1
-
82
-
-
84858159676
-
Antioxidants in Huntington's disease
-
Johri A., Beal M.F. Antioxidants in Huntington's disease. Biochim. Biophys. Acta 2012, 1822(5):664-674.
-
(2012)
Biochim. Biophys. Acta
, vol.1822
, Issue.5
, pp. 664-674
-
-
Johri, A.1
Beal, M.F.2
-
83
-
-
84862792679
-
DNA base excision repair: a mechanism of trinucleotide repeat expansion
-
Liu Y., Wilson S.H. DNA base excision repair: a mechanism of trinucleotide repeat expansion. Trends Biochem. Sci. 2012, 37(4):162-172.
-
(2012)
Trends Biochem. Sci.
, vol.37
, Issue.4
, pp. 162-172
-
-
Liu, Y.1
Wilson, S.H.2
-
84
-
-
70349422148
-
Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease
-
Quintanilla R.A., Johnson G.V. Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease. Brain Res. Bull. 2009, 80(4/5):242-247.
-
(2009)
Brain Res. Bull.
, vol.80
, Issue.4-5
, pp. 242-247
-
-
Quintanilla, R.A.1
Johnson, G.V.2
-
85
-
-
77955267142
-
Chronic inflammation and mutagenesis
-
Ferguson L.R. Chronic inflammation and mutagenesis. Mutat. Res. 2010, 690(1/2):3-11.
-
(2010)
Mutat. Res.
, vol.690
, Issue.1-2
, pp. 3-11
-
-
Ferguson, L.R.1
-
86
-
-
80053252011
-
Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders
-
Doyle K.M., et al. Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders. J. Cell. Mol. Med. 2011, 15(10):2025-2039.
-
(2011)
J. Cell. Mol. Med.
, vol.15
, Issue.10
, pp. 2025-2039
-
-
Doyle, K.M.1
-
87
-
-
80054856662
-
Mitochondria, reactive oxygen species, and chronological aging: a message from yeast
-
Pan Y. Mitochondria, reactive oxygen species, and chronological aging: a message from yeast. Exp. Gerontol. 2011, 46(11):847-852.
-
(2011)
Exp. Gerontol.
, vol.46
, Issue.11
, pp. 847-852
-
-
Pan, Y.1
-
88
-
-
84868115310
-
Neil1 is a genetic modifier of somatic and germline CAG trinucleotide repeat instability in R6/1 mice
-
Mollersen L., et al. Neil1 is a genetic modifier of somatic and germline CAG trinucleotide repeat instability in R6/1 mice. Hum. Mol. Genet. 2012, 21:4939-4947.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 4939-4947
-
-
Mollersen, L.1
-
89
-
-
80053215162
-
DNA slip-outs cause RNA polymerase II arrest in vitro: potential implications for genetic instability
-
Salinas-Rios V., Belotserkovskii B.P., Hanawalt P.C. DNA slip-outs cause RNA polymerase II arrest in vitro: potential implications for genetic instability. Nucleic Acids Res. 2011, 39(17):7444-7454.
-
(2011)
Nucleic Acids Res.
, vol.39
, Issue.17
, pp. 7444-7454
-
-
Salinas-Rios, V.1
Belotserkovskii, B.P.2
Hanawalt, P.C.3
-
90
-
-
79960328293
-
Cockayne syndrome B protein antagonizes OGG1 in modulating CAG repeat length in vivo
-
Kovtun I.V., Johnson K.O., McMurray C.T. Cockayne syndrome B protein antagonizes OGG1 in modulating CAG repeat length in vivo. Aging (Milano) 2011, 3(5):509-514.
-
(2011)
Aging (Milano)
, vol.3
, Issue.5
, pp. 509-514
-
-
Kovtun, I.V.1
Johnson, K.O.2
McMurray, C.T.3
-
91
-
-
81855206487
-
Xpa deficiency reduces CAG trinucleotide repeat instability in neuronal tissues in a mouse model of SCA1
-
Hubert L., et al. Xpa deficiency reduces CAG trinucleotide repeat instability in neuronal tissues in a mouse model of SCA1. Hum. Mol. Genet. 2011, 20(24):4822-4830.
-
(2011)
Hum. Mol. Genet.
, vol.20
, Issue.24
, pp. 4822-4830
-
-
Hubert, L.1
-
92
-
-
38049112778
-
Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells
-
Hegde M.L., Hazra T.K., Mitra S. Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells. Cell Res. 2008, 18(1):27-47.
-
(2008)
Cell Res.
, vol.18
, Issue.1
, pp. 27-47
-
-
Hegde, M.L.1
Hazra, T.K.2
Mitra, S.3
-
93
-
-
0027278557
-
Instability and decay of the primary structure of DNA
-
Lindahl T. Instability and decay of the primary structure of DNA. Nature 1993, 362(6422):709-715.
-
(1993)
Nature
, vol.362
, Issue.6422
, pp. 709-715
-
-
Lindahl, T.1
-
94
-
-
0022456828
-
DNA glycosylases in DNA repair
-
Lindahl T. DNA glycosylases in DNA repair. Basic Life Sci. 1986, 38:335-340.
-
(1986)
Basic Life Sci.
, vol.38
, pp. 335-340
-
-
Lindahl, T.1
-
95
-
-
0020016636
-
DNA repair enzymes
-
Lindahl T. DNA repair enzymes. Annu. Rev. Biochem. 1982, 51:61-87.
-
(1982)
Annu. Rev. Biochem.
, vol.51
, pp. 61-87
-
-
Lindahl, T.1
-
96
-
-
84859749531
-
DNA glycosylases: in DNA repair and beyond
-
Jacobs A.L., Schar P. DNA glycosylases: in DNA repair and beyond. Chromosoma 2012, 121(1):1-20.
-
(2012)
Chromosoma
, vol.121
, Issue.1
, pp. 1-20
-
-
Jacobs, A.L.1
Schar, P.2
-
97
-
-
33644530369
-
Transcriptional inhibition by an oxidized abasic site in DNA
-
Wang Y., et al. Transcriptional inhibition by an oxidized abasic site in DNA. Chem. Res. Toxicol. 2006, 19(2):234-241.
-
(2006)
Chem. Res. Toxicol.
, vol.19
, Issue.2
, pp. 234-241
-
-
Wang, Y.1
-
98
-
-
44949263779
-
The 8,5'-cyclopurine-2'-deoxynucleosides: candidate neurodegenerative DNA lesions in xeroderma pigmentosum, and unique probes of transcription and nucleotide excision repair
-
Brooks P.J. The 8,5'-cyclopurine-2'-deoxynucleosides: candidate neurodegenerative DNA lesions in xeroderma pigmentosum, and unique probes of transcription and nucleotide excision repair. DNA Repair (Amst.) 2008, 7(7):1168-1179.
-
(2008)
DNA Repair (Amst.)
, vol.7
, Issue.7
, pp. 1168-1179
-
-
Brooks, P.J.1
-
99
-
-
84870296240
-
A quantitative assay for assessing the effects of DNA lesions on transcription
-
You C., et al. A quantitative assay for assessing the effects of DNA lesions on transcription. Nat. Chem. Biol. 2012, 8:817-822.
-
(2012)
Nat. Chem. Biol.
, vol.8
, pp. 817-822
-
-
You, C.1
-
100
-
-
77953377798
-
Abasic sites in the transcribed strand of yeast DNA are removed by transcription-coupled nucleotide excision repair
-
Kim N., Jinks-Robertson S. Abasic sites in the transcribed strand of yeast DNA are removed by transcription-coupled nucleotide excision repair. Mol. Cell. Biol. 2010, 30(13):3206-3215.
-
(2010)
Mol. Cell. Biol.
, vol.30
, Issue.13
, pp. 3206-3215
-
-
Kim, N.1
Jinks-Robertson, S.2
-
101
-
-
79960343567
-
Regulation of endonuclease activity in human nucleotide excision repair
-
Fagbemi A.F., Orelli B., Scharer O.D. Regulation of endonuclease activity in human nucleotide excision repair. DNA Repair (Amst.) 2011, 10(7):722-729.
-
(2011)
DNA Repair (Amst.)
, vol.10
, Issue.7
, pp. 722-729
-
-
Fagbemi, A.F.1
Orelli, B.2
Scharer, O.D.3
-
102
-
-
67349212889
-
Coordination of dual incision and repair synthesis in human nucleotide excision repair
-
Staresincic L., et al. Coordination of dual incision and repair synthesis in human nucleotide excision repair. EMBO J. 2009, 28(8):1111-1120.
-
(2009)
EMBO J.
, vol.28
, Issue.8
, pp. 1111-1120
-
-
Staresincic, L.1
-
103
-
-
84859368160
-
Energy landscapes of dynamic ensembles of rolling triplet repeat bulge loops: implications for DNA expansion associated with disease states
-
Volker J., et al. Energy landscapes of dynamic ensembles of rolling triplet repeat bulge loops: implications for DNA expansion associated with disease states. J. Am. Chem. Soc. 2012, 134(13):6033-6044.
-
(2012)
J. Am. Chem. Soc.
, vol.134
, Issue.13
, pp. 6033-6044
-
-
Volker, J.1
-
104
-
-
57449091694
-
Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes
-
Dragileva E., et al. Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes. Neurobiol. Dis. 2009, 33(1):37-47.
-
(2009)
Neurobiol. Dis.
, vol.33
, Issue.1
, pp. 37-47
-
-
Dragileva, E.1
-
105
-
-
33745460647
-
Cockayne syndrome group B protein (CSB) plays a general role in chromatin maintenance and remodeling
-
Newman J.C., Bailey A.D., Weiner A.M. Cockayne syndrome group B protein (CSB) plays a general role in chromatin maintenance and remodeling. Proc. Natl. Acad. Sci. U.S.A. 2006, 103(25):9613-9618.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, Issue.25
, pp. 9613-9618
-
-
Newman, J.C.1
Bailey, A.D.2
Weiner, A.M.3
-
106
-
-
34147136044
-
CREB-binding protein modulates repeat instability in a Drosophila model for polyQ disease
-
Jung J., Bonini N. CREB-binding protein modulates repeat instability in a Drosophila model for polyQ disease. Science 2007, 315(5820):1857-1859.
-
(2007)
Science
, vol.315
, Issue.5820
, pp. 1857-1859
-
-
Jung, J.1
Bonini, N.2
-
107
-
-
65249130165
-
Transcription destabilizes triplet repeats
-
Lin Y., Hubert L., Wilson J.H. Transcription destabilizes triplet repeats. Mol. Carcinog. 2009, 48(4):350-361.
-
(2009)
Mol. Carcinog.
, vol.48
, Issue.4
, pp. 350-361
-
-
Lin, Y.1
Hubert, L.2
Wilson, J.H.3
-
108
-
-
34548204316
-
Transcription-induced CAG repeat contraction in human cells is mediated in part by transcription-coupled nucleotide excision repair
-
Lin Y., Wilson J.H. Transcription-induced CAG repeat contraction in human cells is mediated in part by transcription-coupled nucleotide excision repair. Mol. Cell. Biol. 2007, 27(17):6209-6217.
-
(2007)
Mol. Cell. Biol.
, vol.27
, Issue.17
, pp. 6209-6217
-
-
Lin, Y.1
Wilson, J.H.2
-
109
-
-
33847673066
-
Crosstalk of DNA glycosylases with pathways other than base excision repair
-
Kovtun I.V., McMurray C.T. Crosstalk of DNA glycosylases with pathways other than base excision repair. DNA Repair (Amst.) 2007, 6(4):517-529.
-
(2007)
DNA Repair (Amst.)
, vol.6
, Issue.4
, pp. 517-529
-
-
Kovtun, I.V.1
McMurray, C.T.2
-
110
-
-
0344585940
-
The interacting pathways for prevention and repair of oxidative DNA damage
-
Slupphaug G., Kavli B., Krokan H.E. The interacting pathways for prevention and repair of oxidative DNA damage. Mutat. Res. 2003, 531(1/2):231-251.
-
(2003)
Mutat. Res.
, vol.531
, Issue.1-2
, pp. 231-251
-
-
Slupphaug, G.1
Kavli, B.2
Krokan, H.E.3
-
111
-
-
34547627642
-
Cockayne syndrome B protein stimulates apurinic endonuclease 1 activity and protects against agents that introduce base excision repair intermediates
-
Wong H.K., et al. Cockayne syndrome B protein stimulates apurinic endonuclease 1 activity and protects against agents that introduce base excision repair intermediates. Nucleic Acids Res. 2007, 35(12):4103-4113.
-
(2007)
Nucleic Acids Res.
, vol.35
, Issue.12
, pp. 4103-4113
-
-
Wong, H.K.1
-
112
-
-
23844483200
-
Cooperation of the Cockayne syndrome group B protein and poly(ADP-ribose) polymerase 1 in the response to oxidative stress
-
Thorslund T., et al. Cooperation of the Cockayne syndrome group B protein and poly(ADP-ribose) polymerase 1 in the response to oxidative stress. Mol. Cell. Biol. 2005, 25(17):7625-7636.
-
(2005)
Mol. Cell. Biol.
, vol.25
, Issue.17
, pp. 7625-7636
-
-
Thorslund, T.1
-
113
-
-
0028264043
-
High functioning fragile X males: demonstration of an unmethylated fully expanded FMR-1 mutation associated with protein expression
-
Hagerman R.J., et al. High functioning fragile X males: demonstration of an unmethylated fully expanded FMR-1 mutation associated with protein expression. Am. J. Med. Genet. 1994, 51(4):298-308.
-
(1994)
Am. J. Med. Genet.
, vol.51
, Issue.4
, pp. 298-308
-
-
Hagerman, R.J.1
-
114
-
-
0028857169
-
Normal phenotype in two brothers with a full FMR1 mutation
-
Smeets H.J., et al. Normal phenotype in two brothers with a full FMR1 mutation. Hum. Mol. Genet. 1995, 4(11):2103-2108.
-
(1995)
Hum. Mol. Genet.
, vol.4
, Issue.11
, pp. 2103-2108
-
-
Smeets, H.J.1
-
115
-
-
19944431036
-
Molecular dissection of the events leading to inactivation of the FMR1 gene
-
Pietrobono R., et al. Molecular dissection of the events leading to inactivation of the FMR1 gene. Hum. Mol. Genet. 2005, 14(2):267-277.
-
(2005)
Hum. Mol. Genet.
, vol.14
, Issue.2
, pp. 267-277
-
-
Pietrobono, R.1
-
116
-
-
0031985868
-
In vitro reactivation of the FMR1 gene involved in fragile X syndrome
-
Chiurazzi P., et al. In vitro reactivation of the FMR1 gene involved in fragile X syndrome. Hum. Mol. Genet. 1998, 7(1):109-113.
-
(1998)
Hum. Mol. Genet.
, vol.7
, Issue.1
, pp. 109-113
-
-
Chiurazzi, P.1
-
117
-
-
0032905253
-
Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells
-
Coffee B., et al. Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells. Nat. Genet. 1999, 22(1):98-101.
-
(1999)
Nat. Genet.
, vol.22
, Issue.1
, pp. 98-101
-
-
Coffee, B.1
-
118
-
-
0037100616
-
Quantitative analysis of DNA demethylation and transcriptional reactivation of the FMR1 gene in fragile X cells treated with 5-azadeoxycytidine
-
Pietrobono R., et al. Quantitative analysis of DNA demethylation and transcriptional reactivation of the FMR1 gene in fragile X cells treated with 5-azadeoxycytidine. Nucleic Acids Res. 2002, 30(14):3278-3285.
-
(2002)
Nucleic Acids Res.
, vol.30
, Issue.14
, pp. 3278-3285
-
-
Pietrobono, R.1
-
119
-
-
18844398832
-
Differential epigenetic modifications in the FMR1 gene of the fragile X syndrome after reactivating pharmacological treatments
-
Tabolacci E., et al. Differential epigenetic modifications in the FMR1 gene of the fragile X syndrome after reactivating pharmacological treatments. Eur. J. Hum. Genet. 2005, 13(5):641-648.
-
(2005)
Eur. J. Hum. Genet.
, vol.13
, Issue.5
, pp. 641-648
-
-
Tabolacci, E.1
-
120
-
-
33847688859
-
Repair of alkylated DNA: recent advances
-
Sedgwick B., et al. Repair of alkylated DNA: recent advances. DNA Repair (Amst.) 2007, 6(4):429-442.
-
(2007)
DNA Repair (Amst.)
, vol.6
, Issue.4
, pp. 429-442
-
-
Sedgwick, B.1
-
121
-
-
48249147403
-
Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition
-
Maiti A., et al. Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition. Proc. Natl. Acad. Sci. U.S.A. 2008, 105(26):8890-8895.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, Issue.26
, pp. 8890-8895
-
-
Maiti, A.1
-
122
-
-
45449114804
-
The colorful history of active DNA demethylation
-
Ooi S.K., Bestor T.H. The colorful history of active DNA demethylation. Cell 2008, 133(7):1145-1148.
-
(2008)
Cell
, vol.133
, Issue.7
, pp. 1145-1148
-
-
Ooi, S.K.1
Bestor, T.H.2
-
123
-
-
57649196594
-
DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45
-
Rai K., et al. DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell 2008, 135(7):1201-1212.
-
(2008)
Cell
, vol.135
, Issue.7
, pp. 1201-1212
-
-
Rai, K.1
-
124
-
-
0035942193
-
Overexpression of 5-methylcytosine DNA glycosylase in human embryonic kidney cells EcR293 demethylates the promoter of a hormone-regulated reporter gene
-
Zhu B., et al. Overexpression of 5-methylcytosine DNA glycosylase in human embryonic kidney cells EcR293 demethylates the promoter of a hormone-regulated reporter gene. Proc. Natl. Acad. Sci. U.S.A. 2001, 98(9):5031-5036.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, Issue.9
, pp. 5031-5036
-
-
Zhu, B.1
-
125
-
-
0035504496
-
5-Methylcytosine DNA glycosylase participates in the genome-wide loss of DNA methylation occurring during mouse myoblast differentiation
-
Jost J.P., et al. 5-Methylcytosine DNA glycosylase participates in the genome-wide loss of DNA methylation occurring during mouse myoblast differentiation. Nucleic Acids Res. 2001, 29(21):4452-4461.
-
(2001)
Nucleic Acids Res.
, vol.29
, Issue.21
, pp. 4452-4461
-
-
Jost, J.P.1
-
126
-
-
40449123137
-
Cyclical DNA methylation of a transcriptionally active promoter
-
Metivier R., et al. Cyclical DNA methylation of a transcriptionally active promoter. Nature 2008, 452(7183):45-50.
-
(2008)
Nature
, vol.452
, Issue.7183
, pp. 45-50
-
-
Metivier, R.1
-
127
-
-
33847663262
-
The enigmatic thymine DNA glycosylase
-
Cortazar D., et al. The enigmatic thymine DNA glycosylase. DNA Repair (Amst.) 2007, 6(4):489-504.
-
(2007)
DNA Repair (Amst.)
, vol.6
, Issue.4
, pp. 489-504
-
-
Cortazar, D.1
-
129
-
-
77954313084
-
Genome-wide DNA demethylation in mammals
-
Sanz L.A., Kota S.K., Feil R. Genome-wide DNA demethylation in mammals. Genome Biol. 2010, 11(3):110.
-
(2010)
Genome Biol.
, vol.11
, Issue.3
, pp. 110
-
-
Sanz, L.A.1
Kota, S.K.2
Feil, R.3
-
130
-
-
0035861728
-
Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor
-
Anant S., et al. Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor. J. Biol. Chem. 2001, 276(50):47338-47351.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.50
, pp. 47338-47351
-
-
Anant, S.1
-
131
-
-
10644282845
-
Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming
-
Morgan H.D., et al. Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming. J. Biol. Chem. 2004, 279(50):52353-52360.
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.50
, pp. 52353-52360
-
-
Morgan, H.D.1
-
132
-
-
84860510016
-
Mammalian mismatch repair: error-free or error-prone?
-
Pena-Diaz J., Jiricny J. Mammalian mismatch repair: error-free or error-prone?. Trends Biochem. Sci. 2012, 37(5):206-214.
-
(2012)
Trends Biochem. Sci.
, vol.37
, Issue.5
, pp. 206-214
-
-
Pena-Diaz, J.1
Jiricny, J.2
-
133
-
-
84934878322
-
Nucleotide excision repair in higher eukaryotes: mechanism of primary damage recognition in global genome repair
-
Rechkunova N.I., Lavrik O.I. Nucleotide excision repair in higher eukaryotes: mechanism of primary damage recognition in global genome repair. Subcell. Biochem. 2010, 50:251-277.
-
(2010)
Subcell. Biochem.
, vol.50
, pp. 251-277
-
-
Rechkunova, N.I.1
Lavrik, O.I.2
-
134
-
-
0034086023
-
Thymine-DNA glycosylase and G to A transition mutations at CpG sites
-
Waters T.R., Swann P.F. Thymine-DNA glycosylase and G to A transition mutations at CpG sites. Mutat. Res. 2000, 462(2/3):137-147.
-
(2000)
Mutat. Res.
, vol.462
, Issue.2-3
, pp. 137-147
-
-
Waters, T.R.1
Swann, P.F.2
-
135
-
-
33846885029
-
Substrate specificity of human thymine-DNA glycosylase on exocyclic cytosine adducts
-
Hang B., Guliaev A.B. Substrate specificity of human thymine-DNA glycosylase on exocyclic cytosine adducts. Chem. Biol. Interact. 2007, 165(3):230-238.
-
(2007)
Chem. Biol. Interact.
, vol.165
, Issue.3
, pp. 230-238
-
-
Hang, B.1
Guliaev, A.B.2
-
136
-
-
4344609697
-
Occupancy and synergistic activation of the FMR1 promoter by Nrf-1 and Sp1 in vivo
-
Smith K.T., Coffee B., Reines D. Occupancy and synergistic activation of the FMR1 promoter by Nrf-1 and Sp1 in vivo. Hum. Mol. Genet. 2004, 13(15):1611-1621.
-
(2004)
Hum. Mol. Genet.
, vol.13
, Issue.15
, pp. 1611-1621
-
-
Smith, K.T.1
Coffee, B.2
Reines, D.3
-
137
-
-
26444595255
-
AP-2alpha selectively regulates fragile X mental retardation-1 gene transcription during embryonic development
-
Lim J.H., et al. AP-2alpha selectively regulates fragile X mental retardation-1 gene transcription during embryonic development. Hum. Mol. Genet. 2005, 14(14):2027-2034.
-
(2005)
Hum. Mol. Genet.
, vol.14
, Issue.14
, pp. 2027-2034
-
-
Lim, J.H.1
-
138
-
-
33644860083
-
The gene encoding the fragile X RNA-binding protein is controlled by nuclear respiratory factor 2 and the CREB family of transcription factors
-
Smith K.T., Nicholls R.D., Reines D. The gene encoding the fragile X RNA-binding protein is controlled by nuclear respiratory factor 2 and the CREB family of transcription factors. Nucleic Acids Res. 2006, 34(4):1205-1215.
-
(2006)
Nucleic Acids Res.
, vol.34
, Issue.4
, pp. 1205-1215
-
-
Smith, K.T.1
Nicholls, R.D.2
Reines, D.3
-
139
-
-
0032718839
-
Sp1 and AP2 transcription factors are required for the human fragile mental retardation promoter activity in SK-N-SH neuronal cells
-
Carrillo C., Cisneros B., Montanez C. Sp1 and AP2 transcription factors are required for the human fragile mental retardation promoter activity in SK-N-SH neuronal cells. Neurosci. Lett. 1999, 276(3):149-152.
-
(1999)
Neurosci. Lett.
, vol.276
, Issue.3
, pp. 149-152
-
-
Carrillo, C.1
Cisneros, B.2
Montanez, C.3
-
140
-
-
0036184090
-
Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription
-
Tini M., et al. Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription. Mol. Cell 2002, 9(2):265-277.
-
(2002)
Mol. Cell
, vol.9
, Issue.2
, pp. 265-277
-
-
Tini, M.1
-
141
-
-
33845733594
-
SUMO-1-dependent allosteric regulation of thymine DNA glycosylase alters subnuclear localization and CBP/p300 recruitment
-
Mohan R.D., et al. SUMO-1-dependent allosteric regulation of thymine DNA glycosylase alters subnuclear localization and CBP/p300 recruitment. Mol. Cell. Biol. 2007, 27(1):229-243.
-
(2007)
Mol. Cell. Biol.
, vol.27
, Issue.1
, pp. 229-243
-
-
Mohan, R.D.1
-
142
-
-
0141755305
-
T:G mismatch-specific thymine-DNA glycosylase potentiates transcription of estrogen-regulated genes through direct interaction with estrogen receptor alpha
-
Chen D., et al. T:G mismatch-specific thymine-DNA glycosylase potentiates transcription of estrogen-regulated genes through direct interaction with estrogen receptor alpha. J. Biol. Chem. 2003, 278(40):38586-38592.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.40
, pp. 38586-38592
-
-
Chen, D.1
-
143
-
-
0348044518
-
Imprinting of the MEA Polycomb gene is controlled by antagonism between MET1 methyltransferase and DME glycosylase
-
Xiao W., et al. Imprinting of the MEA Polycomb gene is controlled by antagonism between MET1 methyltransferase and DME glycosylase. Dev. Cell 2003, 5(6):891-901.
-
(2003)
Dev. Cell
, vol.5
, Issue.6
, pp. 891-901
-
-
Xiao, W.1
-
144
-
-
37249050851
-
Genetic interactions between DNA demethylation and methylation in Arabidopsis
-
Penterman J., Uzawa R., Fischer R.L. Genetic interactions between DNA demethylation and methylation in Arabidopsis. Plant Physiol. 2007, 145(4):1549-1557.
-
(2007)
Plant Physiol.
, vol.145
, Issue.4
, pp. 1549-1557
-
-
Penterman, J.1
Uzawa, R.2
Fischer, R.L.3
-
145
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M., et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 2009, 324(5929):930-935.
-
(2009)
Science
, vol.324
, Issue.5929
, pp. 930-935
-
-
Tahiliani, M.1
-
146
-
-
79551587102
-
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells
-
Koh K.P., et al. Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell 2011, 8(2):200-213.
-
(2011)
Cell Stem Cell
, vol.8
, Issue.2
, pp. 200-213
-
-
Koh, K.P.1
-
147
-
-
80052461558
-
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
-
Ito S., et al. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 2011, 333(6047):1300-1303.
-
(2011)
Science
, vol.333
, Issue.6047
, pp. 1300-1303
-
-
Ito, S.1
-
148
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
-
Ito S., et al. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 2010, 466(7310):1129-1133.
-
(2010)
Nature
, vol.466
, Issue.7310
, pp. 1129-1133
-
-
Ito, S.1
-
149
-
-
84555189745
-
DNA methylation: TET proteins-guardians of CpG islands?
-
Williams K., Christensen J., Helin K. DNA methylation: TET proteins-guardians of CpG islands?. EMBO Rep. 2012, 13(1):28-35.
-
(2012)
EMBO Rep.
, vol.13
, Issue.1
, pp. 28-35
-
-
Williams, K.1
Christensen, J.2
Helin, K.3
-
150
-
-
84860749868
-
Tet family proteins and 5-hydroxymethylcytosine in development and disease
-
Tan L., Shi Y.G. Tet family proteins and 5-hydroxymethylcytosine in development and disease. Development 2012, 139(11):1895-1902.
-
(2012)
Development
, vol.139
, Issue.11
, pp. 1895-1902
-
-
Tan, L.1
Shi, Y.G.2
-
151
-
-
82955207588
-
Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation
-
Wu H., Zhang Y. Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation. Genes Dev. 2011, 25(23):2436-2452.
-
(2011)
Genes Dev.
, vol.25
, Issue.23
, pp. 2436-2452
-
-
Wu, H.1
Zhang, Y.2
-
152
-
-
80051712275
-
Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond
-
Guo J.U., et al. Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond. Cell Cycle 2011, 10(16):2662-2668.
-
(2011)
Cell Cycle
, vol.10
, Issue.16
, pp. 2662-2668
-
-
Guo, J.U.1
-
153
-
-
83855163995
-
Uncovering the role of 5-hydroxymethylcytosine in the epigenome
-
Branco M.R., Ficz G., Reik W. Uncovering the role of 5-hydroxymethylcytosine in the epigenome. Nat. Rev. Genet. 2012, 13(1):7-13.
-
(2012)
Nat. Rev. Genet.
, vol.13
, Issue.1
, pp. 7-13
-
-
Branco, M.R.1
Ficz, G.2
Reik, W.3
-
154
-
-
79956302047
-
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
-
Williams K., et al. TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 2011, 473(7347):343-348.
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 343-348
-
-
Williams, K.1
-
155
-
-
79956292024
-
Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells
-
Wu H., et al. Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells. Nature 2011, 473(7347):389-393.
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 389-393
-
-
Wu, H.1
-
156
-
-
79955948324
-
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells
-
Xu Y., et al. Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells. Mol. Cell 2011, 42(4):451-464.
-
(2011)
Mol. Cell
, vol.42
, Issue.4
, pp. 451-464
-
-
Xu, Y.1
-
157
-
-
78650826181
-
Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates
-
Globisch D., et al. Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates. PLoS ONE 2010, 5(12):e15367.
-
(2010)
PLoS ONE
, vol.5
, Issue.12
-
-
Globisch, D.1
-
158
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
-
Kriaucionis S., Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 2009, 324(5929):929-930.
-
(2009)
Science
, vol.324
, Issue.5929
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
|