Energy landscapes of dynamic ensembles of rolling triplet repeat bulge loops: Implications for DNA expansion associated with disease states

Journal of the American Chemical Society

Volumn 134, Issue 13, 2012, Pages 6033-6044

  Völker, Jens ^a   Gindikin, Vera ^a   Klump, Horst H ^b   Plum, G Eric ^c   Breslauer, Kenneth J ^a,d  

^a RUTGERS UNIVERSITY   (United States)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c IBET Inc   (United States)

^d RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABSORBANCES; CONFORMATIONAL COMPLEXITY; CONFORMATIONAL SPACE; DIRECTED LOOPS; DISEASE STATE; DNA REPEATS; DNA SECONDARY STRUCTURES; DYNAMIC ENSEMBLE; ENERGY LANDSCAPE; LOOP STRUCTURE; PROCESSING MACHINERY; STATIC AND DYNAMIC; STRATEGIC SITING; STRUCTURAL DIVERSITY;

EXPANSION; ISOMERS; MACHINERY;

DNA;

OLIGOMER; REPETITIVE DNA;

ARTICLE; DNA CONFORMATION; DNA DENATURATION; ENERGY; ENTHALPY; ISOMER;

BASE PAIRING; BASE SEQUENCE; DISEASE; DNA; FLUORESCENT DYES; OLIGODEOXYRIBONUCLEOTIDES; THERMODYNAMICS; TRANSITION TEMPERATURE; TRINUCLEOTIDE REPEATS;

EID: 84859368160     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja3010896     Document Type: Article

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