-
1
-
-
0029968460
-
Trinucleotide repeats in neurogenetic disorders
-
Paulson H.L., Fischbeck K.H. Trinucleotide repeats in neurogenetic disorders. Annu. Rev. Neurosci. 1996, 19:79-107.
-
(1996)
Annu. Rev. Neurosci.
, vol.19
, pp. 79-107
-
-
Paulson, H.L.1
Fischbeck, K.H.2
-
2
-
-
77958109197
-
Mechanisms of trinucleotide repeat instability during human development
-
McMurray C.T. Mechanisms of trinucleotide repeat instability during human development. Nat. Rev. Genet. 2010, 11:786-799.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 786-799
-
-
McMurray, C.T.1
-
3
-
-
25844438495
-
Repeat instability: mechanisms of dynamic mutations
-
Pearson C.E., et al. Repeat instability: mechanisms of dynamic mutations. Nat. Rev. Genet. 2005, 6:729-742.
-
(2005)
Nat. Rev. Genet.
, vol.6
, pp. 729-742
-
-
Pearson, C.E.1
-
4
-
-
34249337762
-
OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells
-
Kovtun I.V., et al. OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells. Nature 2007, 447:447-452.
-
(2007)
Nature
, vol.447
, pp. 447-452
-
-
Kovtun, I.V.1
-
5
-
-
0346752132
-
Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis
-
Kennedy L., et al. Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis. Hum. Mol. Genet. 2003, 12:3359-3367.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 3359-3367
-
-
Kennedy, L.1
-
6
-
-
0030058075
-
Molecular basis of genetic instability of triplet repeats
-
Wells R.D. Molecular basis of genetic instability of triplet repeats. J. Biol. Chem. 1996, 271:2875-2878.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2875-2878
-
-
Wells, R.D.1
-
7
-
-
0040269264
-
Studies of DNA polymereases in replication-based repeat expansion
-
Academic Press, R.D. Wells, S.T. Warren (Eds.)
-
Wilson S.H., et al. Studies of DNA polymereases in replication-based repeat expansion. Genetic Instabilities and Neurological Disease 1998, 693-698. Academic Press. 1st edn. R.D. Wells, S.T. Warren (Eds.).
-
(1998)
Genetic Instabilities and Neurological Disease
, pp. 693-698
-
-
Wilson, S.H.1
-
8
-
-
0033514926
-
DNA secondary structure: a common and causative factor for expansion in human disease
-
McMurray C.T. DNA secondary structure: a common and causative factor for expansion in human disease. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:1823-1825.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 1823-1825
-
-
McMurray, C.T.1
-
9
-
-
44949205290
-
Hijacking of the mismatch repair system to cause CAG expansion and cell death in neurodegenerative disease
-
McMurray C.T. Hijacking of the mismatch repair system to cause CAG expansion and cell death in neurodegenerative disease. DNA Repair 2008, 7:1121-1134.
-
(2008)
DNA Repair
, vol.7
, pp. 1121-1134
-
-
McMurray, C.T.1
-
10
-
-
0035065524
-
Trinucleotide expansion in haploid germ cells by gap repair
-
Kovtun I.V, McMurray C.T. Trinucleotide expansion in haploid germ cells by gap repair. Nat. Genet. 2001, 27:407-411.
-
(2001)
Nat. Genet.
, vol.27
, pp. 407-411
-
-
Kovtun, I.V.1
McMurray, C.T.2
-
11
-
-
0030752987
-
Human MSH2 binds to trinucleotide repeat DNA structures associated with neurodegenerative diseases
-
Pearson C.E., et al. Human MSH2 binds to trinucleotide repeat DNA structures associated with neurodegenerative diseases. Hum. Mol. Genet. 1997, 6:1117-1123.
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 1117-1123
-
-
Pearson, C.E.1
-
12
-
-
0032708840
-
Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice
-
Manley K., et al. Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice. Nat. Genet. 1999, 23:471-473.
-
(1999)
Nat. Genet.
, vol.23
, pp. 471-473
-
-
Manley, K.1
-
13
-
-
0033556218
-
Nucleotide excision repair affects the stability of long transcribed (CTG*CAG) tracts in an orientation-dependent manner in Escherichia coli
-
Parniewski P., et al. Nucleotide excision repair affects the stability of long transcribed (CTG*CAG) tracts in an orientation-dependent manner in Escherichia coli. Nucleic Acids Res. 1999, 27:616-623.
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 616-623
-
-
Parniewski, P.1
-
14
-
-
32244438870
-
Transcription promotes contraction of CAG repeat tracts in human cells
-
Lin Y., et al. Transcription promotes contraction of CAG repeat tracts in human cells. Nat. Struct. Mol. Biol. 2006, 13:179-180.
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 179-180
-
-
Lin, Y.1
-
15
-
-
34548204316
-
Transcription-induced CAG repeat contraction in human cells is mediated in part by transcription-coupled nucleotide excision repair
-
Lin Y., Wilson J.H. Transcription-induced CAG repeat contraction in human cells is mediated in part by transcription-coupled nucleotide excision repair. Mol. Cell. Biol. 2007, 27:6209-6217.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 6209-6217
-
-
Lin, Y.1
Wilson, J.H.2
-
16
-
-
0034658187
-
Recombination-induced CAG trinucleotide repeat expansions in yeast involve the MRE11-RAD50-XRS2 complex
-
Richard G.F., et al. Recombination-induced CAG trinucleotide repeat expansions in yeast involve the MRE11-RAD50-XRS2 complex. EMBO J. 2000, 19:2381-2390.
-
(2000)
EMBO J.
, vol.19
, pp. 2381-2390
-
-
Richard, G.F.1
-
17
-
-
0037405845
-
Long CTG tracts from the myotonic dystrophy gene induce deletions and rearrangements during recombination at the APRT locus in CHO cells
-
Meservy J.L., et al. Long CTG tracts from the myotonic dystrophy gene induce deletions and rearrangements during recombination at the APRT locus in CHO cells. Mol. Cell. Biol. 2003, 23:3152-3162.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 3152-3162
-
-
Meservy, J.L.1
-
18
-
-
8444231721
-
Non-B DNA conformations, genomic rearrangements, and human disease
-
Bacolla A., Wells R.D. Non-B DNA conformations, genomic rearrangements, and human disease. J. Biol. Chem. 2004, 279:47411-47414.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 47411-47414
-
-
Bacolla, A.1
Wells, R.D.2
-
19
-
-
22244446185
-
Advances in mechanisms of genetic instability related to hereditary neurological diseases
-
Wells R.D., et al. Advances in mechanisms of genetic instability related to hereditary neurological diseases. Nucleic Acids Res. 2005, 33:3785-3798.
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 3785-3798
-
-
Wells, R.D.1
-
20
-
-
80053215162
-
DNA slip-outs cause RNA polymerase II arrest in vitro: potential implications for genetic instability
-
Salinas-Rios V., et al. DNA slip-outs cause RNA polymerase II arrest in vitro: potential implications for genetic instability. Nucleic Acids Res. 2011, 39:7444-7454.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 7444-7454
-
-
Salinas-Rios, V.1
-
21
-
-
25844468819
-
(CAG)(n)-hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition
-
Owen B.A., et al. (CAG)(n)-hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition. Nat. Struct. Mol. Biol. 2005, 12:663-670.
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 663-670
-
-
Owen, B.A.1
-
22
-
-
0026795635
-
Protein oxidation and aging
-
Stadtman E.R. Protein oxidation and aging. Science 1992, 257:1220-1224.
-
(1992)
Science
, vol.257
, pp. 1220-1224
-
-
Stadtman, E.R.1
-
23
-
-
0032751079
-
Oxidative DNA damage in the aging mouse brain
-
Cardozo-Pelaez F., et al. Oxidative DNA damage in the aging mouse brain. Mov. Disord. 1999, 14:972-980.
-
(1999)
Mov. Disord.
, vol.14
, pp. 972-980
-
-
Cardozo-Pelaez, F.1
-
24
-
-
61649106707
-
Environmental-induced oxidative stress in neurodegenerative disorders and aging
-
Migliore L., Coppede F. Environmental-induced oxidative stress in neurodegenerative disorders and aging. Mutat. Res. 2009, 674:73-84.
-
(2009)
Mutat. Res.
, vol.674
, pp. 73-84
-
-
Migliore, L.1
Coppede, F.2
-
25
-
-
0030816108
-
Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae
-
Radicella J.P., et al. Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. U.S.A. 1997, 94:8010-8015.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 8010-8015
-
-
Radicella, J.P.1
-
26
-
-
0032836651
-
Initiation of base excision repair: glycosylase mechanisms and structures
-
McCullough A.K., et al. Initiation of base excision repair: glycosylase mechanisms and structures. Annu. Rev. Biochem. 1999, 68:255-285.
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 255-285
-
-
McCullough, A.K.1
-
27
-
-
33847007529
-
The mechanics of base excision repair, and its relationship to aging and disease
-
Wilson D.M., Bohr V.A. The mechanics of base excision repair, and its relationship to aging and disease. DNA Repair 2007, 6:544-559.
-
(2007)
DNA Repair
, vol.6
, pp. 544-559
-
-
Wilson, D.M.1
Bohr, V.A.2
-
28
-
-
38349130992
-
Efficient removal of formamidopyrimidines by 8-oxoguanine glycosylases
-
Krishnamurthy N., et al. Efficient removal of formamidopyrimidines by 8-oxoguanine glycosylases. Biochemistry 2008, 47:1043-1050.
-
(2008)
Biochemistry
, vol.47
, pp. 1043-1050
-
-
Krishnamurthy, N.1
-
29
-
-
33644634986
-
Structure and mechanism of DNA polymerase beta
-
Beard W.A., Wilson S.H. Structure and mechanism of DNA polymerase beta. Chem. Rev. 2006, 106:361-382.
-
(2006)
Chem. Rev.
, vol.106
, pp. 361-382
-
-
Beard, W.A.1
Wilson, S.H.2
-
30
-
-
78650399787
-
Substrate channeling in mammalian base excision repair pathways: passing the baton
-
Prasad R., et al. Substrate channeling in mammalian base excision repair pathways: passing the baton. J. Biol. Chem. 2010, 285:40479-40488.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 40479-40488
-
-
Prasad, R.1
-
31
-
-
78149469632
-
Base excision repair and design of small molecule inhibitors of human DNA polymerase beta
-
Wilson S.H., et al. Base excision repair and design of small molecule inhibitors of human DNA polymerase beta. Cell. Mol. Life Sci. 2010, 67:3633-3647.
-
(2010)
Cell. Mol. Life Sci.
, vol.67
, pp. 3633-3647
-
-
Wilson, S.H.1
-
32
-
-
13544261768
-
DNA polymerase beta and flap endonuclease 1 enzymatic specificities sustain DNA synthesis for long patch base excision repair
-
Liu Y., et al. DNA polymerase beta and flap endonuclease 1 enzymatic specificities sustain DNA synthesis for long patch base excision repair. J. Biol. Chem. 2005, 280:3665-3674.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 3665-3674
-
-
Liu, Y.1
-
33
-
-
79953894934
-
Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily
-
Tsutakawa S.E., et al. Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily. Cell 2011, 145:198-211.
-
(2011)
Cell
, vol.145
, pp. 198-211
-
-
Tsutakawa, S.E.1
-
34
-
-
0034616199
-
Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1
-
Tom S., et al. Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1. J. Biol. Chem. 2000, 275:10498-10505.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10498-10505
-
-
Tom, S.1
-
35
-
-
0037163025
-
Direct interaction between mammalian DNA polymerase beta and proliferating cell nuclear antigen
-
Kedar P.S., et al. Direct interaction between mammalian DNA polymerase beta and proliferating cell nuclear antigen. J. Biol. Chem. 2002, 277:31115-31123.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 31115-31123
-
-
Kedar, P.S.1
-
36
-
-
34548261232
-
HMGB1 is a cofactor in mammalian base excision repair
-
Prasad R., et al. HMGB1 is a cofactor in mammalian base excision repair. Mol. Cell 2007, 27:829-841.
-
(2007)
Mol. Cell
, vol.27
, pp. 829-841
-
-
Prasad, R.1
-
37
-
-
0034641887
-
Dramatic mutation instability in HD mouse striatum: does polyglutamine load contribute to cell-specific vulnerability in Huntington's disease?
-
Kennedy L., Shelbourne P.F. Dramatic mutation instability in HD mouse striatum: does polyglutamine load contribute to cell-specific vulnerability in Huntington's disease?. Hum. Mol. Genet. 2000, 9:2539-2544.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2539-2544
-
-
Kennedy, L.1
Shelbourne, P.F.2
-
38
-
-
0035668684
-
Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease
-
Bogdanov M.B., et al. Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease. J. Neurochem. 2001, 79:1246-1249.
-
(2001)
J. Neurochem.
, vol.79
, pp. 1246-1249
-
-
Bogdanov, M.B.1
-
39
-
-
70350503915
-
Coordination between polymerase beta and FEN1 can modulate CAG repeat expansion
-
Liu Y., et al. Coordination between polymerase beta and FEN1 can modulate CAG repeat expansion. J. Biol. Chem. 2009, 284:28352-28366.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 28352-28366
-
-
Liu, Y.1
-
40
-
-
0344586043
-
Mutagenicity, toxicity and repair of DNA base damage induced by oxidation
-
Bjelland S., Seeberg E. Mutagenicity, toxicity and repair of DNA base damage induced by oxidation. Mutat. Res. 2003, 531:37-80.
-
(2003)
Mutat. Res.
, vol.531
, pp. 37-80
-
-
Bjelland, S.1
Seeberg, E.2
-
41
-
-
3042631024
-
Gene regulation and DNA damage in the ageing human brain
-
Lu T., et al. Gene regulation and DNA damage in the ageing human brain. Nature 2004, 429:883-891.
-
(2004)
Nature
, vol.429
, pp. 883-891
-
-
Lu, T.1
-
42
-
-
0031054051
-
Enzymes and reactions at the eukaryotic DNA replication fork
-
Bambara R.A., et al. Enzymes and reactions at the eukaryotic DNA replication fork. J. Biol. Chem. 1997, 272:4647-4650.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4647-4650
-
-
Bambara, R.A.1
-
43
-
-
0030957997
-
Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1)
-
Klungland A., Lindahl T. Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1). EMBO J. 1997, 16:3341-3348.
-
(1997)
EMBO J.
, vol.16
, pp. 3341-3348
-
-
Klungland, A.1
Lindahl, T.2
-
44
-
-
0031442653
-
A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair
-
Tishkoff D.X., et al. A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair. Cell 1997, 88:253-263.
-
(1997)
Cell
, vol.88
, pp. 253-263
-
-
Tishkoff, D.X.1
-
45
-
-
0034595842
-
Inhibition of flap endonuclease 1 by flap secondary structure and relevance to repeat sequence expansion
-
Henricksen L.A., et al. Inhibition of flap endonuclease 1 by flap secondary structure and relevance to repeat sequence expansion. J. Biol. Chem. 2000, 275:16420-16427.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16420-16427
-
-
Henricksen, L.A.1
-
46
-
-
0037515705
-
Analysis of human flap endonuclease 1 mutants reveals a mechanism to prevent triplet repeat expansion
-
Liu Y., Bambara R.A. Analysis of human flap endonuclease 1 mutants reveals a mechanism to prevent triplet repeat expansion. J. Biol. Chem. 2003, 278:13728-13739.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 13728-13739
-
-
Liu, Y.1
Bambara, R.A.2
-
47
-
-
1942422156
-
Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stability
-
Liu Y., et al. Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stability. Mol. Cell. Biol. 2004, 24:4049-4064.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 4049-4064
-
-
Liu, Y.1
-
48
-
-
0042470700
-
Nuclease-deficient FEN-1 blocks Rad51/BRCA1-mediated repair and causes trinucleotide repeat instability
-
Spiro C., McMurray C.T. Nuclease-deficient FEN-1 blocks Rad51/BRCA1-mediated repair and causes trinucleotide repeat instability. Mol. Cell. Biol. 2003, 23:6063-6074.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 6063-6074
-
-
Spiro, C.1
McMurray, C.T.2
-
49
-
-
0033369989
-
Inhibition of FEN-1 processing by DNA secondary structure at trinucleotide repeats
-
Spiro C., et al. Inhibition of FEN-1 processing by DNA secondary structure at trinucleotide repeats. Mol. Cell 1999, 4:1079-1085.
-
(1999)
Mol. Cell
, vol.4
, pp. 1079-1085
-
-
Spiro, C.1
-
50
-
-
3943086339
-
Flap endonuclease 1: a central component of DNA metabolism
-
Liu Y., et al. Flap endonuclease 1: a central component of DNA metabolism. Annu. Rev. Biochem. 2004, 73:589-615.
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 589-615
-
-
Liu, Y.1
-
51
-
-
0037177823
-
Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate
-
Kao H.I., et al. Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate. J. Biol. Chem. 2002, 277:14379-14389.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 14379-14389
-
-
Kao, H.I.1
-
52
-
-
0032544112
-
The role of SOS and flap processing in microsatellite instability in Escherichia coli
-
Morel P., et al. The role of SOS and flap processing in microsatellite instability in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:10003-10008.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 10003-10008
-
-
Morel, P.1
-
53
-
-
0036165352
-
The roles of Klenow processing and flap processing activities of DNA polymerase I in chromosome instability in Escherichia coli K12 strains
-
Nagata Y., et al. The roles of Klenow processing and flap processing activities of DNA polymerase I in chromosome instability in Escherichia coli K12 strains. Genetics 2002, 160:13-23.
-
(2002)
Genetics
, vol.160
, pp. 13-23
-
-
Nagata, Y.1
-
54
-
-
0029039868
-
Requirement of the yeast RTH1 5' to 3' exonuclease for the stability of simple repetitive DNA
-
Johnson R.E., et al. Requirement of the yeast RTH1 5' to 3' exonuclease for the stability of simple repetitive DNA. Science 1995, 269:238-240.
-
(1995)
Science
, vol.269
, pp. 238-240
-
-
Johnson, R.E.1
-
55
-
-
0031953438
-
Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t)
-
Kokoska R.J., et al. Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t). Mol. Cell. Biol. 1998, 18:2779-2788.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2779-2788
-
-
Kokoska, R.J.1
-
56
-
-
0032488872
-
Expansion and length-dependent fragility of CTG repeats in yeast
-
Freudenreich C.H., et al. Expansion and length-dependent fragility of CTG repeats in yeast. Science 1998, 279:853-856.
-
(1998)
Science
, vol.279
, pp. 853-856
-
-
Freudenreich, C.H.1
-
57
-
-
0032771002
-
Stability of the human fragile X (CGG)(n) triplet repeat array in Saccharomyces cerevisiae deficient in aspects of DNA metabolism
-
White P.J., et al. Stability of the human fragile X (CGG)(n) triplet repeat array in Saccharomyces cerevisiae deficient in aspects of DNA metabolism. Mol. Cell. Biol. 1999, 19:5675-5684.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 5675-5684
-
-
White, P.J.1
-
58
-
-
0031965224
-
Expansions of CAG repeat tracts are frequent in a yeast mutant defective in Okazaki fragment maturation
-
Schweitzer J.K., Livingston D.M. Expansions of CAG repeat tracts are frequent in a yeast mutant defective in Okazaki fragment maturation. Hum. Mol. Genet. 1998, 7:69-74.
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 69-74
-
-
Schweitzer, J.K.1
Livingston, D.M.2
-
59
-
-
34047261259
-
Haploinsufficiency of yeast FEN1 causes instability of expanded CAG/CTG tracts in a length-dependent manner
-
Yang J., Freudenreich C.H. Haploinsufficiency of yeast FEN1 causes instability of expanded CAG/CTG tracts in a length-dependent manner. Gene 2007, 393:110-115.
-
(2007)
Gene
, vol.393
, pp. 110-115
-
-
Yang, J.1
Freudenreich, C.H.2
-
60
-
-
0035793560
-
DNA structure and aspartate 276 influence nucleotide binding to human DNA polymerase beta. Implication for the identity of the rate-limiting conformational change
-
Vande Berg B.J., et al. DNA structure and aspartate 276 influence nucleotide binding to human DNA polymerase beta. Implication for the identity of the rate-limiting conformational change. J. Biol. Chem. 2001, 276:3408-3416.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3408-3416
-
-
Vande Berg, B.J.1
-
61
-
-
74249102052
-
Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice
-
Goula A.V., et al. Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice. PLoS Genet. 2009, 5:e1000749.
-
(2009)
PLoS Genet.
, vol.5
-
-
Goula, A.V.1
-
62
-
-
33748783811
-
Fen1 does not control somatic hypermutability of the (CTG)(n)*(CAG)(n) repeat in a knock-in mouse model for DM1
-
van den Broek W.J., et al. Fen1 does not control somatic hypermutability of the (CTG)(n)*(CAG)(n) repeat in a knock-in mouse model for DM1. FEBS Lett. 2006, 580:5208-5214.
-
(2006)
FEBS Lett.
, vol.580
, pp. 5208-5214
-
-
van den Broek, W.J.1
-
63
-
-
77951773059
-
Potassium bromate, a potent DNA oxidizing agent, exacerbates germline repeat expansion in a fragile X premutation mouse model
-
Entezam A., et al. Potassium bromate, a potent DNA oxidizing agent, exacerbates germline repeat expansion in a fragile X premutation mouse model. Hum. Mutat. 2010, 31:611-616.
-
(2010)
Hum. Mutat.
, vol.31
, pp. 611-616
-
-
Entezam, A.1
-
64
-
-
77956551200
-
Complementary roles for exonuclease 1 and Flap endonuclease 1 in maintenance of triplet repeats
-
Vallur A.C., Maizels N. Complementary roles for exonuclease 1 and Flap endonuclease 1 in maintenance of triplet repeats. J. Biol. Chem. 2010, 285:28514-28519.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 28514-28519
-
-
Vallur, A.C.1
Maizels, N.2
-
65
-
-
43449125903
-
Huntingtin triplet-repeat locus is stable under long-term Fen1 knockdown in human cells
-
Moe S.E., et al. Huntingtin triplet-repeat locus is stable under long-term Fen1 knockdown in human cells. J. Neurosci. Methods 2008, 171:233-238.
-
(2008)
J. Neurosci. Methods
, vol.171
, pp. 233-238
-
-
Moe, S.E.1
-
66
-
-
0035099276
-
The 'flap' endonuclease gene FEN1 is excluded as a candidate gene implicated in the CAG repeat expansion underlying Huntington disease
-
Otto C.J., et al. The 'flap' endonuclease gene FEN1 is excluded as a candidate gene implicated in the CAG repeat expansion underlying Huntington disease. Clin. Genet. 2001, 59:122-127.
-
(2001)
Clin. Genet.
, vol.59
, pp. 122-127
-
-
Otto, C.J.1
-
67
-
-
14844300882
-
A SCA7 CAG/CTG repeat expansion is stable in Drosophila melanogaster despite modulation of genomic context and gene dosage
-
Jackson S.M., et al. A SCA7 CAG/CTG repeat expansion is stable in Drosophila melanogaster despite modulation of genomic context and gene dosage. Gene 2005, 347:35-41.
-
(2005)
Gene
, vol.347
, pp. 35-41
-
-
Jackson, S.M.1
-
68
-
-
67650501195
-
Structure-dependent DNA damage and repair in a trinucleotide repeat sequence
-
Jarem D.A., et al. Structure-dependent DNA damage and repair in a trinucleotide repeat sequence. Biochemistry 2009, 48:6655-6663.
-
(2009)
Biochemistry
, vol.48
, pp. 6655-6663
-
-
Jarem, D.A.1
-
69
-
-
79960698114
-
Incidence and persistence of 8-oxo-7,8-dihydroguanine within a hairpin intermediate exacerbates a toxic oxidation cycle associated with trinucleotide repeat expansion
-
Jarem D.A., et al. Incidence and persistence of 8-oxo-7,8-dihydroguanine within a hairpin intermediate exacerbates a toxic oxidation cycle associated with trinucleotide repeat expansion. DNA Repair 2011, 10:887-896.
-
(2011)
DNA Repair
, vol.10
, pp. 887-896
-
-
Jarem, D.A.1
-
70
-
-
74549121930
-
HMGB1: roles in base excision repair and related function
-
Liu Y., et al. HMGB1: roles in base excision repair and related function. Biochim. Biophys. Acta 2010, 1799:119-130.
-
(2010)
Biochim. Biophys. Acta
, vol.1799
, pp. 119-130
-
-
Liu, Y.1
-
71
-
-
20044369162
-
Parp-1 deficiency causes an increase of deletion mutations and insertions/rearrangements in vivo after treatment with an alkylating agent
-
Shibata A., et al. Parp-1 deficiency causes an increase of deletion mutations and insertions/rearrangements in vivo after treatment with an alkylating agent. Oncogene 2005, 24:1328-1337.
-
(2005)
Oncogene
, vol.24
, pp. 1328-1337
-
-
Shibata, A.1
-
72
-
-
68249141774
-
Incision-dependent and error-free repair of (CAG)(n)/(CTG)(n) hairpins in human cell extracts
-
Hou C., et al. Incision-dependent and error-free repair of (CAG)(n)/(CTG)(n) hairpins in human cell extracts. Nat. Struct. Mol. Biol. 2009, 16:869-875.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 869-875
-
-
Hou, C.1
-
73
-
-
25844524498
-
Slipped (CTG)*(CAG) repeats can be correctly repaired, escape repair or undergo error-prone repair
-
Panigrahi G.B., et al. Slipped (CTG)*(CAG) repeats can be correctly repaired, escape repair or undergo error-prone repair. Nat. Struct. Mol. Biol. 2005, 12:654-662.
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 654-662
-
-
Panigrahi, G.B.1
-
74
-
-
26944440117
-
Toward a unified theory for repeat expansions
-
Mirkin S.M. Toward a unified theory for repeat expansions. Nat. Struct. Mol. Biol. 2005, 12:635-637.
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 635-637
-
-
Mirkin, S.M.1
-
75
-
-
38049112778
-
Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells
-
Hegde M.L., et al. Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells. Cell Res. 2008, 18:27-47.
-
(2008)
Cell Res.
, vol.18
, pp. 27-47
-
-
Hegde, M.L.1
|