Pathogenic mechanisms of a polyglutamine-mediated neurodegenerative disease, Spinocerebellar ataxia type 1

Journal of Biological Chemistry

Volumn 284, Issue 12, 2009, Pages 7425-7429

  Zoghbi, Huda Y ^a   Orr, Harry T ^b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR PROTEINS; COGNITIVE IMPAIRMENT; ENCODED PROTEINS; GAIN-OF FUNCTION; GENETIC STUDIES; MOTOR CO-ORDINATION; NEURODEGENERATIVE DISEASE; NORMAL FUNCTION; PATHOGENIC MECHANISMS; POLYGLUTAMINE; SPASTICITY;

ATAXIN 1; CELL PROTEIN; POLYGLUTAMINE; SERINE; ATAXIN-1; NERVE PROTEIN; NUCLEAR PROTEIN; PEPTIDE;

COGNITIVE DEFECT; DEGENERATIVE DISEASE; GAIN OF FUNCTION MUTATION; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; LOSS OF FUNCTION MUTATION; MOTOR DYSFUNCTION; MUTATIONAL ANALYSIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SHORT SURVEY; SLURRED SPEECH; SPASTICITY; SPINOCEREBELLAR DEGENERATION TYPE 1; TRINUCLEOTIDE REPEAT; ANIMAL; GENETICS; METABOLISM; REVIEW; SPINOCEREBELLAR DEGENERATION;

ANIMALS; HUMANS; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PEPTIDES; SPINOCEREBELLAR ATAXIAS; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 65549134765     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.R800041200     Document Type: Short Survey

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