메뉴 건너뛰기




Volumn 49, Issue 8, 2013, Pages 738-746

The cancer stem cell hypothesis applied to oral carcinoma

Author keywords

Oral cancer; Proliferation; Stem cell

Indexed keywords

CANCER STEM CELL; CARCINOGENESIS; HUMAN; MORTALITY; MOUTH CARCINOMA; MOUTH SQUAMOUS CELL CARCINOMA; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; STOCHASTIC MODEL;

EID: 84880054123     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2013.04.002     Document Type: Review
Times cited : (46)

References (184)
  • 1
    • 0042928497 scopus 로고    scopus 로고
    • Multiple primary tumours following head and neck cancer in southern England during 1961-98
    • K.A.A.S. Warnakulasuriya, D. Robinson, and H. Evans Multiple primary tumours following head and neck cancer in southern England during 1961-98 J Oral Pathol Med 32 8 2003 443 449
    • (2003) J Oral Pathol Med , vol.32 , Issue.8 , pp. 443-449
    • Warnakulasuriya, K.A.A.S.1    Robinson, D.2    Evans, H.3
  • 3
    • 33646682821 scopus 로고    scopus 로고
    • Disease mechanism and biomarkers of oral squamous cell carcinoma
    • B.M.N. Brinkman, and D.T.W. Wong Disease mechanism and biomarkers of oral squamous cell carcinoma Curr Opin Oncol 18 3 2006 228 233
    • (2006) Curr Opin Oncol , vol.18 , Issue.3 , pp. 228-233
    • Brinkman, B.M.N.1    Wong, D.T.W.2
  • 4
    • 33644560281 scopus 로고    scopus 로고
    • Cancer stem cells: An old idea - A paradigm shift
    • M. Wicha, S. Liu, and G. Dontu Cancer stem cells: an old idea - a paradigm shift Cancer Res 66 4 2006 1883 1890
    • (2006) Cancer Res , vol.66 , Issue.4 , pp. 1883-1890
    • Wicha, M.1    Liu, S.2    Dontu, G.3
  • 5
    • 28544449786 scopus 로고    scopus 로고
    • A tumour stem cell hypothesis for the origins of prostate cancer
    • N.J. Maitland, and A. Collins A tumour stem cell hypothesis for the origins of prostate cancer BJU Int 96 9 2005 1219 1223
    • (2005) BJU Int , vol.96 , Issue.9 , pp. 1219-1223
    • Maitland, N.J.1    Collins, A.2
  • 7
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • T. Reya, S.J. Morrison, M.F. Clarke, and I.L. Weissman Stem cells, cancer, and cancer stem cells Nature 414 6859 2001 105 111
    • (2001) Nature , vol.414 , Issue.6859 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 8
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • M.J. Evans, and M.H. Kaufman Establishment in culture of pluripotential cells from mouse embryos Nature 292 5819 1981 154 156
    • (1981) Nature , vol.292 , Issue.5819 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 9
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • G. Martin Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells Proc Natl Acad Sci USA 78 12 1981 7634 7638
    • (1981) Proc Natl Acad Sci USA , vol.78 , Issue.12 , pp. 7634-7638
    • Martin, G.1
  • 10
    • 84855900675 scopus 로고    scopus 로고
    • The biology of head and neck cancer stem cells
    • Z. Zhang, M.S. Filho, and J.E. Nör The biology of head and neck cancer stem cells Oral Oncol 48 1 2012 1 9
    • (2012) Oral Oncol , vol.48 , Issue.1 , pp. 1-9
    • Zhang, Z.1    Filho, M.S.2    Nör, J.E.3
  • 11
    • 45549096766 scopus 로고    scopus 로고
    • Cancer stem cells: A step toward the cure
    • B.M. Boman, and M.S. Wicha Cancer stem cells: a step toward the cure J Clin Oncol 26 17 2008 2795 2799
    • (2008) J Clin Oncol , vol.26 , Issue.17 , pp. 2795-2799
    • Boman, B.M.1    Wicha, M.S.2
  • 12
    • 77956214387 scopus 로고    scopus 로고
    • Tumor-initiating cells are rare in many human tumors
    • K. Ishizawa, Z. Rasheed, and R. Karisch Tumor-initiating cells are rare in many human tumors Cell Stem Cell 7 3 2010 279 282
    • (2010) Cell Stem Cell , vol.7 , Issue.3 , pp. 279-282
    • Ishizawa, K.1    Rasheed, Z.2    Karisch, R.3
  • 13
    • 0019391823 scopus 로고
    • Cell replacement in epidermis (keratopoiesis) via discrete units of proliferation
    • C.S. Potten Cell replacement in epidermis (keratopoiesis) via discrete units of proliferation Int Rev Cytol 69 1981 271 318
    • (1981) Int Rev Cytol , vol.69 , pp. 271-318
    • Potten, C.S.1
  • 14
    • 0035868759 scopus 로고    scopus 로고
    • Multiple classes of stem cells in cutaneous epithelium: A lineage analysis of adult mouse skin
    • S. Ghazizadeh, and L.B. Taichman Multiple classes of stem cells in cutaneous epithelium: a lineage analysis of adult mouse skin EMBO J 20 6 2001 1215 1222
    • (2001) EMBO J , vol.20 , Issue.6 , pp. 1215-1222
    • Ghazizadeh, S.1    Taichman, L.B.2
  • 15
    • 0036063084 scopus 로고    scopus 로고
    • Epidermal stem cells
    • S.M. Janes, S. Lowell, and C. Hutter Epidermal stem cells J Pathol 197 4 2002 479 491
    • (2002) J Pathol , vol.197 , Issue.4 , pp. 479-491
    • Janes, S.M.1    Lowell, S.2    Hutter, C.3
  • 16
    • 33646899057 scopus 로고    scopus 로고
    • Stem cell properties and epithelial malignancies
    • I.C. Mackenzie Stem cell properties and epithelial malignancies Eur J Cancer 42 9 2006 1204 1212
    • (2006) Eur J Cancer , vol.42 , Issue.9 , pp. 1204-1212
    • Mackenzie, I.C.1
  • 17
    • 0032998902 scopus 로고    scopus 로고
    • The spatial relationship between stem cells and their progeny in the basal layer of human epidermis: A new view based on whole-mount labelling and lineage analysis
    • U.B. Jensen, S. Lowell, and F.M. Watt The spatial relationship between stem cells and their progeny in the basal layer of human epidermis: a new view based on whole-mount labelling and lineage analysis Development 126 11 1999 2409 2418
    • (1999) Development , vol.126 , Issue.11 , pp. 2409-2418
    • Jensen, U.B.1    Lowell, S.2    Watt, F.M.3
  • 18
    • 33750313208 scopus 로고    scopus 로고
    • Cancer stem cells-perspectives on current status and future directions: AACR Workshop on cancer stem cells
    • M.F. Clarke, J.E. Dick, P.B. Dirks, C.J. Eaves, C.H.M. Jamieson, and D.L. Jones Cancer stem cells-perspectives on current status and future directions: AACR Workshop on cancer stem cells Cancer Res 66 19 2006 9339 9344
    • (2006) Cancer Res , vol.66 , Issue.19 , pp. 9339-9344
    • Clarke, M.F.1    Dick, J.E.2    Dirks, P.B.3    Eaves, C.J.4    Jamieson, C.H.M.5    Jones, D.L.6
  • 19
    • 84861194295 scopus 로고    scopus 로고
    • Cancer stem cells and metastasis
    • K. Sampieri, and R. Fodde Cancer stem cells and metastasis Semin Cancer Biol 22 3 2012 187 193
    • (2012) Semin Cancer Biol , vol.22 , Issue.3 , pp. 187-193
    • Sampieri, K.1    Fodde, R.2
  • 20
    • 18544380391 scopus 로고    scopus 로고
    • Deranged expression of the E-cadherin/beta-catenin complex and the epidermal growth factor receptor in the clinical evolution and progression of oral squamous cell carcinomas
    • A. Bánkfalvi, M. Krassort, A. Végh, E. Felszeghy, and J. Piffkó Deranged expression of the E-cadherin/beta-catenin complex and the epidermal growth factor receptor in the clinical evolution and progression of oral squamous cell carcinomas J Oral Pathol Med 31 8 2002 450 457
    • (2002) J Oral Pathol Med , vol.31 , Issue.8 , pp. 450-457
    • Bánkfalvi, A.1    Krassort, M.2    Végh, A.3    Felszeghy, E.4    Piffkó, J.5
  • 21
    • 0038354620 scopus 로고    scopus 로고
    • Intratumoral genomic heterogeneity in advanced head and neck cancer detected by comparative genomic hybridization
    • S.C. Tremmel, K. Götte, S. Popp, S. Weber, K. Hörmann, and C.R. Bartram Intratumoral genomic heterogeneity in advanced head and neck cancer detected by comparative genomic hybridization Cancer Genet Cytogenet 144 2 2003 165 174
    • (2003) Cancer Genet Cytogenet , vol.144 , Issue.2 , pp. 165-174
    • Tremmel, S.C.1    Götte, K.2    Popp, S.3    Weber, S.4    Hörmann, K.5    Bartram, C.R.6
  • 22
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
    • J.E. Visvader, and G.J. Lindeman Cancer stem cells in solid tumours: accumulating evidence and unresolved questions Nat Rev Cancer 8 10 2008 755 768
    • (2008) Nat Rev Cancer , vol.8 , Issue.10 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 23
    • 0345059767 scopus 로고    scopus 로고
    • Applying the principles of stem-cell biology to cancer
    • R. Pardal, M.F. Clarke, and S.J. Morrison Applying the principles of stem-cell biology to cancer Nat Rev Cancer 3 12 2003 895 902
    • (2003) Nat Rev Cancer , vol.3 , Issue.12 , pp. 895-902
    • Pardal, R.1    Clarke, M.F.2    Morrison, S.J.3
  • 24
    • 47749110683 scopus 로고    scopus 로고
    • Cancer stem cell model in oral squamous cell carcinoma
    • Z.-T. Zhou, and W.-W. Jiang Cancer stem cell model in oral squamous cell carcinoma Curr Stem Cell Res Ther 3 1 2008 4
    • (2008) Curr Stem Cell Res Ther , vol.3 , Issue.1 , pp. 4
    • Zhou, Z.-T.1    Jiang, W.-W.2
  • 25
    • 33747442707 scopus 로고    scopus 로고
    • Cancer stem cells - New and potentially important targets for the therapy of oral squamous cell carcinoma
    • D.E. Costea, O. Tsinkalovsky, O.K. Vintermyr, A.C. Johannessen, and I.C. Mackenzie Cancer stem cells - new and potentially important targets for the therapy of oral squamous cell carcinoma Oral Dis 12 5 2006 443 454
    • (2006) Oral Dis , vol.12 , Issue.5 , pp. 443-454
    • Costea, D.E.1    Tsinkalovsky, O.2    Vintermyr, O.K.3    Johannessen, A.C.4    Mackenzie, I.C.5
  • 26
    • 84865732644 scopus 로고    scopus 로고
    • The utility of CD44, CD117 and CD133 in identification of cancer stem cells (CSC) in oral squamous cell carcinomas (OSCC)
    • C. Märgäritescu, D. Pirici, C. Simionescu, and A. Stepan The utility of CD44, CD117 and CD133 in identification of cancer stem cells (CSC) in oral squamous cell carcinomas (OSCC) Rom J Morphol Embryol 52 2011 985 993
    • (2011) Rom J Morphol Embryol , vol.52 , pp. 985-993
    • Märgäritescu, C.1    Pirici, D.2    Simionescu, C.3    Stepan, A.4
  • 27
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • D. Bonnet, and J.E. Dick Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell Nat Med 3 7 1997 730 737
    • (1997) Nat Med , vol.3 , Issue.7 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 30
    • 34250306257 scopus 로고    scopus 로고
    • Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells
    • M.M. Ho, A.V. Ng, S. Lam, and J.Y. Hung Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells Cancer Res 67 10 2007 4827 4833
    • (2007) Cancer Res , vol.67 , Issue.10 , pp. 4827-4833
    • Ho, M.M.1    Ng, A.V.2    Lam, S.3    Hung, J.Y.4
  • 31
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • C. O'Brien, A. Pollett, S. Gallinger, and J. Dick A human colon cancer cell capable of initiating tumour growth in immunodeficient mice Nature 445 7123 2006 106 110
    • (2006) Nature , vol.445 , Issue.7123 , pp. 106-110
    • O'Brien, C.1    Pollett, A.2    Gallinger, S.3    Dick, J.4
  • 32
    • 34548455927 scopus 로고    scopus 로고
    • Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
    • P.C. Hermann, S.L. Huber, T. Herrler, A. Aicher, J.W. Ellwart, and M. Guba Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer Cell Stem Cell 1 3 2007 313 323
    • (2007) Cell Stem Cell , vol.1 , Issue.3 , pp. 313-323
    • Hermann, P.C.1    Huber, S.L.2    Herrler, T.3    Aicher, A.4    Ellwart, J.W.5    Guba, M.6
  • 33
    • 38549139140 scopus 로고    scopus 로고
    • Significance of CD90+ cancer stem cells in human liver cancer
    • Z. Yang, D. Ho, M. Ng, C. Lau, and W. Yu Significance of CD90+ cancer stem cells in human liver cancer Cancer Cell 13 2 2008 153 166
    • (2008) Cancer Cell , vol.13 , Issue.2 , pp. 153-166
    • Yang, Z.1    Ho, D.2    Ng, M.3    Lau, C.4    Yu, W.5
  • 34
    • 27144557960 scopus 로고    scopus 로고
    • A tumorigenic subpopulation with stem cell properties in melanomas
    • D. Fang, T.K. Nguyen, K. Leishear, R. Finko, A.N. Kulp, and S. Hotz A tumorigenic subpopulation with stem cell properties in melanomas Cancer Res 65 20 2005 9328 9337
    • (2005) Cancer Res , vol.65 , Issue.20 , pp. 9328-9337
    • Fang, D.1    Nguyen, T.K.2    Leishear, K.3    Finko, R.4    Kulp, A.N.5    Hotz, S.6
  • 35
    • 35848964790 scopus 로고    scopus 로고
    • Breast tumor heterogeneity: Cancer stem cells or clonal evolution?
    • L. Campbell, and K. Polyak Breast tumor heterogeneity: cancer stem cells or clonal evolution? Cell Cycle 6 19 2007 2332 2338
    • (2007) Cell Cycle , vol.6 , Issue.19 , pp. 2332-2338
    • Campbell, L.1    Polyak, K.2
  • 36
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • P.C. Nowell The clonal evolution of tumor cell populations Science 194 4260 1976 23 28
    • (1976) Science , vol.194 , Issue.4260 , pp. 23-28
    • Nowell, P.C.1
  • 37
    • 0028091194 scopus 로고
    • A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
    • T. Lapidot, C. Sirard, J. Vormoor, B. Murdoch, T. Hoang, and J. Caceres-Cortes A cell initiating human acute myeloid leukaemia after transplantation into SCID mice Nature 367 6464 1994 645 648
    • (1994) Nature , vol.367 , Issue.6464 , pp. 645-648
    • Lapidot, T.1    Sirard, C.2    Vormoor, J.3    Murdoch, B.4    Hoang, T.5    Caceres-Cortes, J.6
  • 38
    • 33846512398 scopus 로고    scopus 로고
    • Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
    • M.E. Prince, R. Sivanandan, A. Kaczorowski, G.T. Wolf, M.J. Kaplan, and P. Dalerba Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma Proc Natl Acad Sci USA 104 3 2007 973 978
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.3 , pp. 973-978
    • Prince, M.E.1    Sivanandan, R.2    Kaczorowski, A.3    Wolf, G.T.4    Kaplan, M.J.5    Dalerba, P.6
  • 40
    • 20444397431 scopus 로고    scopus 로고
    • Identification of bronchioalveolar stem cells in normal lung and lung cancer
    • C.F.B. Kim, E.L. Jackson, A.E. Woolfenden, S. Lawrence, I. Babar, and S. Vogel Identification of bronchioalveolar stem cells in normal lung and lung cancer Cell 121 6 2005 823 835
    • (2005) Cell , vol.121 , Issue.6 , pp. 823-835
    • Kim, C.F.B.1    Jackson, E.L.2    Woolfenden, A.E.3    Lawrence, S.4    Babar, I.5    Vogel, S.6
  • 41
    • 28244472369 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic prostate cancer stem cells
    • A.T. Collins, P.A. Berry, C. Hyde, M.J. Stower, and N.J. Maitland Prospective identification of tumorigenic prostate cancer stem cells Cancer Res 65 23 2005 10946 10951
    • (2005) Cancer Res , vol.65 , Issue.23 , pp. 10946-10951
    • Collins, A.T.1    Berry, P.A.2    Hyde, C.3    Stower, M.J.4    Maitland, N.J.5
  • 43
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • K.W. Kinzler, and B. Vogelstein Lessons from hereditary colorectal cancer Cell 87 2 1996 159 170
    • (1996) Cell , vol.87 , Issue.2 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 44
    • 0037079003 scopus 로고    scopus 로고
    • Rules for making human tumor cells
    • W.C. Hahn, and R.A. Weinberg Rules for making human tumor cells N Engl J Med 347 20 2002 1593 1603
    • (2002) N Engl J Med , vol.347 , Issue.20 , pp. 1593-1603
    • Hahn, W.C.1    Weinberg, R.A.2
  • 45
    • 9344247476 scopus 로고    scopus 로고
    • Genetic progression model for head and neck cancer: Implications for field cancerization
    • J. Califano, P. Van der Riet, W. Westra, H. Nawroz, G. Clayman, and S. Piantadosi Genetic progression model for head and neck cancer: implications for field cancerization Cancer Res 56 11 1996 2488 2492
    • (1996) Cancer Res , vol.56 , Issue.11 , pp. 2488-2492
    • Califano, J.1    Van Der Riet, P.2    Westra, W.3    Nawroz, H.4    Clayman, G.5    Piantadosi, S.6
  • 46
    • 0033966575 scopus 로고    scopus 로고
    • Genetic progression and clonal relationship of recurrent premalignant head and neck lesions
    • J. Califano, W.H. Westra, G. Meininger, R. Corio, W.M. Koch, and D. Sidransky Genetic progression and clonal relationship of recurrent premalignant head and neck lesions Clin Cancer Res 6 2 2000 347 352
    • (2000) Clin Cancer Res , vol.6 , Issue.2 , pp. 347-352
    • Califano, J.1    Westra, W.H.2    Meininger, G.3    Corio, R.4    Koch, W.M.5    Sidransky, D.6
  • 47
    • 0035120289 scopus 로고    scopus 로고
    • Chromosomal alterations in squamous cell carcinomas of the head and neck: Window to the biology of disease
    • S.M. Gollin Chromosomal alterations in squamous cell carcinomas of the head and neck: window to the biology of disease Head Neck 23 March 2001 238 253
    • (2001) Head Neck , vol.23 , Issue.MARCH , pp. 238-253
    • Gollin, S.M.1
  • 48
    • 0028294877 scopus 로고
    • Maturation arrest of stem cell differentiation is a common pathway for the cellular origin of teratocarcinomas and epithelial cancers
    • S. Sell, and G.B. Pierce Maturation arrest of stem cell differentiation is a common pathway for the cellular origin of teratocarcinomas and epithelial cancers Lab Invest 70 1 1994 6 22
    • (1994) Lab Invest , vol.70 , Issue.1 , pp. 6-22
    • Sell, S.1    Pierce, G.B.2
  • 49
    • 0026017392 scopus 로고
    • Leukemia and the disruption of normal hematopoiesis
    • C.L. Sawyers, C.T. Denny, and O.N. Witte Leukemia and the disruption of normal hematopoiesis Cell 64 2 1991 337 350
    • (1991) Cell , vol.64 , Issue.2 , pp. 337-350
    • Sawyers, C.L.1    Denny, C.T.2    Witte, O.N.3
  • 50
    • 0033694305 scopus 로고    scopus 로고
    • Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling
    • B. Varnum-Finney, L. Xu, C. Brashem-Stein, C. Nourigat, D. Flowers, and S. Bakkour Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling Nat Med 6 11 2000 1278 1281
    • (2000) Nat Med , vol.6 , Issue.11 , pp. 1278-1281
    • Varnum-Finney, B.1    Xu, L.2    Brashem-Stein, C.3    Nourigat, C.4    Flowers, D.5    Bakkour, S.6
  • 51
    • 0034613734 scopus 로고    scopus 로고
    • The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells
    • F.N. Karanu, B. Murdoch, L. Gallacher, D.M. Wu, M. Koremoto, and S. Sakano The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells J Exp Med 192 9 2000 1365 1372
    • (2000) J Exp Med , vol.192 , Issue.9 , pp. 1365-1372
    • Karanu, F.N.1    Murdoch, B.2    Gallacher, L.3    Wu, D.M.4    Koremoto, M.5    Sakano, S.6
  • 52
    • 0035257660 scopus 로고    scopus 로고
    • Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation
    • G. Bhardwaj, B. Murdoch, D. Wu, D.P. Baker, K.P. Williams, and K. Chadwick Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation Nat Immunol 2 2 2001 172 180
    • (2001) Nat Immunol , vol.2 , Issue.2 , pp. 172-180
    • Bhardwaj, G.1    Murdoch, B.2    Wu, D.3    Baker, D.P.4    Williams, K.P.5    Chadwick, K.6
  • 53
    • 0029841366 scopus 로고    scopus 로고
    • Mutations in the human homologue of Drosophila patched (PTCH) in basal cell carcinomas and the Gorlin syndrome: Different in vivo mechanisms of PTCH inactivation
    • A.B. Unden, E. Holmberg, B. Lundh-Rozell, M. Stähle-Bäckdahl, P.G. Zaphiropoulos, and R. Toftgård Mutations in the human homologue of Drosophila patched (PTCH) in basal cell carcinomas and the Gorlin syndrome: different in vivo mechanisms of PTCH inactivation Cancer Res 56 20 1996 4562 4565
    • (1996) Cancer Res , vol.56 , Issue.20 , pp. 4562-4565
    • Unden, A.B.1    Holmberg, E.2    Lundh-Rozell, B.3    Stähle-Bäckdahl, M.4    Zaphiropoulos, P.G.5    Toftgård, R.6
  • 54
    • 6044243650 scopus 로고    scopus 로고
    • Hedgehog signalling in prostate regeneration, neoplasia and metastasis
    • S.S. Karhadkar, G.S. Bova, N. Abdallah, S. Dhara, D. Gardner, and A. Maitra Hedgehog signalling in prostate regeneration, neoplasia and metastasis Nature 431 7009 2004 707 712
    • (2004) Nature , vol.431 , Issue.7009 , pp. 707-712
    • Karhadkar, S.S.1    Bova, G.S.2    Abdallah, N.3    Dhara, S.4    Gardner, D.5    Maitra, A.6
  • 55
    • 13144298531 scopus 로고    scopus 로고
    • Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors
    • C.L. Olsen, P.-P. Hsu, J. Glienke, G.M. Rubanyi, and A.R. Brooks Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors BMC cancer 4 2004 43
    • (2004) BMC Cancer , vol.4 , pp. 43
    • Olsen, C.L.1    Hsu, P.-P.2    Glienke, J.3    Rubanyi, G.M.4    Brooks, A.R.5
  • 56
    • 0033613401 scopus 로고    scopus 로고
    • Involvement of Notch1 in the development of mouse mammary tumors
    • A. Diévart, N. Beaulieu, and P. Jolicoeur Involvement of Notch1 in the development of mouse mammary tumors Oncogene 18 44 1999 5973 5981
    • (1999) Oncogene , vol.18 , Issue.44 , pp. 5973-5981
    • Diévart, A.1    Beaulieu, N.2    Jolicoeur, P.3
  • 57
    • 0036679649 scopus 로고    scopus 로고
    • Notch signaling as a therapeutic target
    • Y. Nam, J.C. Aster, and S.C. Blacklow Notch signaling as a therapeutic target Curr Opin Chem Biol 6 4 2002 501 509
    • (2002) Curr Opin Chem Biol , vol.6 , Issue.4 , pp. 501-509
    • Nam, Y.1    Aster, J.C.2    Blacklow, S.C.3
  • 58
    • 0242456129 scopus 로고    scopus 로고
    • Notch signaling as a therapeutic target in cancer: A new approach to the development of cell fate modifying agents
    • B.J. Nickoloff, B.A. Osborne, and L. Miele Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents Oncogene 22 42 2003 6598 6608
    • (2003) Oncogene , vol.22 , Issue.42 , pp. 6598-6608
    • Nickoloff, B.J.1    Osborne, B.A.2    Miele, L.3
  • 59
    • 3042559889 scopus 로고    scopus 로고
    • The Notch and Sonic hedgehog signalling pathways in immunity
    • R.A. Benson, J.A. Lowrey, J.R. Lamb, and S.E.M. Howie The Notch and Sonic hedgehog signalling pathways in immunity Mol Immunol 41 6-7 2004 715 725
    • (2004) Mol Immunol , vol.41 , Issue.67 , pp. 715-725
    • Benson, R.A.1    Lowrey, J.A.2    Lamb, J.R.3    Howie, S.E.M.4
  • 60
    • 0030989287 scopus 로고    scopus 로고
    • A role for the Wnt gene family in hematopoiesis: Expansion of multilineage progenitor cells
    • T.W. Austin, G.P. Solar, F.C. Ziegler, L. Liem, and W. Matthews A role for the Wnt gene family in hematopoiesis: expansion of multilineage progenitor cells Blood 89 10 1997 3624 3635
    • (1997) Blood , vol.89 , Issue.10 , pp. 3624-3635
    • Austin, T.W.1    Solar, G.P.2    Ziegler, F.C.3    Liem, L.4    Matthews, W.5
  • 61
    • 0032212190 scopus 로고    scopus 로고
    • Role of members of the Wnt gene family in human hematopoiesis
    • D.J. Van Den Berg, A.K. Sharma, E. Bruno, and R. Hoffman Role of members of the Wnt gene family in human hematopoiesis Blood 92 9 1998 3189 3202
    • (1998) Blood , vol.92 , Issue.9 , pp. 3189-3202
    • Van Den Berg, D.J.1    Sharma, A.K.2    Bruno, E.3    Hoffman, R.4
  • 62
    • 0032567078 scopus 로고    scopus 로고
    • De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin
    • U. Gat, R. DasGupta, L. Degenstein, and E. Fuchs De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin Cell 95 5 1998 605 614
    • (1998) Cell , vol.95 , Issue.5 , pp. 605-614
    • Gat, U.1    Dasgupta, R.2    Degenstein, L.3    Fuchs, E.4
  • 63
    • 84864277298 scopus 로고    scopus 로고
    • Aberrant expression of β-catenin and its association with Δnp63, Notch-1, and clinicopathological factors in oral squamous cell carcinoma
    • G. Ravindran, and H. Devaraj Aberrant expression of β-catenin and its association with ΔNp63, Notch-1, and clinicopathological factors in oral squamous cell carcinoma Clin Oral Invest 16 4 2012 1275 1288
    • (2012) Clin Oral Invest , vol.16 , Issue.4 , pp. 1275-1288
    • Ravindran, G.1    Devaraj, H.2
  • 64
    • 76349117690 scopus 로고    scopus 로고
    • Upregulation of vimentin and aberrant expression of E-cadherin/beta- catenin complex in oral squamous cell carcinomas: Correlation with the clinicopathological features and patient outcome
    • L.-K. Liu, X.-Y. Jiang, X.-X. Zhou, D.-M. Wang, X.-L. Song, and H.-B. Jiang Upregulation of vimentin and aberrant expression of E-cadherin/beta- catenin complex in oral squamous cell carcinomas: correlation with the clinicopathological features and patient outcome Mod Pathol 23 2 2010 213 224
    • (2010) Mod Pathol , vol.23 , Issue.2 , pp. 213-224
    • Liu, L.-K.1    Jiang, X.-Y.2    Zhou, X.-X.3    Wang, D.-M.4    Song, X.-L.5    Jiang, H.-B.6
  • 65
    • 81155153654 scopus 로고    scopus 로고
    • Dickkopf (Dkk)-3 and β-catenin expressions increased in the transition from normal oral mucosal to oral squamous cell carcinoma
    • M. Fujii, N. Katase, M. Lefeuvre, M. Gunduz, R.R. Buery, and R. Tamamura Dickkopf (Dkk)-3 and β-catenin expressions increased in the transition from normal oral mucosal to oral squamous cell carcinoma J Mol Histol 42 6 2011 499 504
    • (2011) J Mol Histol , vol.42 , Issue.6 , pp. 499-504
    • Fujii, M.1    Katase, N.2    Lefeuvre, M.3    Gunduz, M.4    Buery, R.R.5    Tamamura, R.6
  • 66
    • 77957862980 scopus 로고    scopus 로고
    • Involvement of the Wnt-β-catenin pathway in invasion and migration of oral squamous carcinoma cells
    • S. Iwai, A. Yonekawa, C. Harada, M. Hamada, W. Katagiri, and M. Nakazawa Involvement of the Wnt-β-catenin pathway in invasion and migration of oral squamous carcinoma cells Int J Oncol 37 5 2010 1095 1103
    • (2010) Int J Oncol , vol.37 , Issue.5 , pp. 1095-1103
    • Iwai, S.1    Yonekawa, A.2    Harada, C.3    Hamada, M.4    Katagiri, W.5    Nakazawa, M.6
  • 67
    • 24344506258 scopus 로고    scopus 로고
    • Cancer stem cells: Lessons from leukemia
    • J.C.Y. Wang, and J.E. Dick Cancer stem cells: lessons from leukemia Trends Cell Biol 15 9 2005 494 501
    • (2005) Trends Cell Biol , vol.15 , Issue.9 , pp. 494-501
    • Wang, J.C.Y.1    Dick, J.E.2
  • 68
    • 0036591968 scopus 로고    scopus 로고
    • Intestinal stem cells protect their genome by selective segregation of template DNA strands
    • C.S. Potten, G. Owen, and D. Booth Intestinal stem cells protect their genome by selective segregation of template DNA strands J Cell Sci 115 Pt 11 2002 2381 2388
    • (2002) J Cell Sci , vol.115 , Issue.PART 11 , pp. 2381-2388
    • Potten, C.S.1    Owen, G.2    Booth, D.3
  • 69
    • 19444372265 scopus 로고    scopus 로고
    • Survival of mammary stem cells in suspension culture: Implications for stem cell biology and neoplasia
    • G. Dontu, and M.S. Wicha Survival of mammary stem cells in suspension culture: implications for stem cell biology and neoplasia J Mammary Gland Biol Neoplasia 10 1 2005 75 86
    • (2005) J Mammary Gland Biol Neoplasia , vol.10 , Issue.1 , pp. 75-86
    • Dontu, G.1    Wicha, M.S.2
  • 70
    • 85047690508 scopus 로고    scopus 로고
    • Opinion: The origin of the cancer stem cell: Current controversies and new insights
    • R. Bjerkvig, B.B. Tysnes, K.S. Aboody, J. Najbauer, and A.J.A. Terzis Opinion: the origin of the cancer stem cell: current controversies and new insights Nat Rev Cancer 5 11 2005 899 904
    • (2005) Nat Rev Cancer , vol.5 , Issue.11 , pp. 899-904
    • Bjerkvig, R.1    Tysnes, B.B.2    Aboody, K.S.3    Najbauer, J.4    Terzis, A.J.A.5
  • 71
    • 1542328965 scopus 로고    scopus 로고
    • Plasticity of adult stem cells
    • A.J. Wagers, and I.L. Weissman Plasticity of adult stem cells Cell 116 5 2004 639 648
    • (2004) Cell , vol.116 , Issue.5 , pp. 639-648
    • Wagers, A.J.1    Weissman, I.L.2
  • 72
    • 9444265320 scopus 로고    scopus 로고
    • Gastric cancer originating from bone marrow-derived cells
    • J. Houghton, C. Stoicov, S. Nomura, A.B. Rogers, J. Carlson, and H. Li Gastric cancer originating from bone marrow-derived cells Science 306 5701 2004 1568 1571
    • (2004) Science , vol.306 , Issue.5701 , pp. 1568-1571
    • Houghton, J.1    Stoicov, C.2    Nomura, S.3    Rogers, A.B.4    Carlson, J.5    Li, H.6
  • 73
    • 0032972372 scopus 로고    scopus 로고
    • Beta-catenin signalling modulates proliferative potential of human epidermal keratinocytes independently of intercellular adhesion
    • A.J. Zhu, and F.M. Watt Beta-catenin signalling modulates proliferative potential of human epidermal keratinocytes independently of intercellular adhesion Development 126 10 1999 2285 2298
    • (1999) Development , vol.126 , Issue.10 , pp. 2285-2298
    • Zhu, A.J.1    Watt, F.M.2
  • 74
    • 0038819885 scopus 로고    scopus 로고
    • Stem-cell hierarchy in skin cancer
    • J. Perez-Losada, and A. Balmain Stem-cell hierarchy in skin cancer Nat Rev Cancer 3 6 2003 434 443
    • (2003) Nat Rev Cancer , vol.3 , Issue.6 , pp. 434-443
    • Perez-Losada, J.1    Balmain, A.2
  • 76
    • 46949085597 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
    • D. Huangfu, R. Maehr, W. Guo, A. Eijkelenboom, M. Snitow, and A.E. Chen Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds Nat Biotechnol 26 7 2008 795 797
    • (2008) Nat Biotechnol , vol.26 , Issue.7 , pp. 795-797
    • Huangfu, D.1    Maehr, R.2    Guo, W.3    Eijkelenboom, A.4    Snitow, M.5    Chen, A.E.6
  • 77
    • 77950865895 scopus 로고    scopus 로고
    • Potential role of HDAC inhibitors in cancer therapy: Insights into oral squamous cell carcinoma
    • A. Iglesias-Linares, R.M. Yañez-Vico, and M.A. González- Moles Potential role of HDAC inhibitors in cancer therapy: insights into oral squamous cell carcinoma Oral Oncol 46 5 2010 323 329
    • (2010) Oral Oncol , vol.46 , Issue.5 , pp. 323-329
    • Iglesias-Linares, A.1    Yañez-Vico, R.M.2    González-Moles, M.A.3
  • 78
    • 0033789680 scopus 로고    scopus 로고
    • The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
    • E. Batlle, E. Sancho, C. Francí, D. Domínguez, M. Monfar, and J. Baulida The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells Nat Cell Biol 2 2 2000 84 89
    • (2000) Nat Cell Biol , vol.2 , Issue.2 , pp. 84-89
    • Batlle, E.1    Sancho, E.2    Francí, C.3    Domínguez, D.4    Monfar, M.5    Baulida, J.6
  • 79
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • S.A. Mani, W. Guo, M.-J. Liao, E.N. Eaton, A. Ayyanan, and A.Y. Zhou The epithelial-mesenchymal transition generates cells with properties of stem cells Cell 133 4 2008 704 715
    • (2008) Cell , vol.133 , Issue.4 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.-J.3    Eaton, E.N.4    Ayyanan, A.5    Zhou, A.Y.6
  • 80
    • 2942707848 scopus 로고    scopus 로고
    • Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
    • J. Yang, S.A. Mani, J.L. Donaher, S. Ramaswamy, R.A. Itzykson, and C. Come Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis Cell 117 7 2004 927 939
    • (2004) Cell , vol.117 , Issue.7 , pp. 927-939
    • Yang, J.1    Mani, S.A.2    Donaher, J.L.3    Ramaswamy, S.4    Itzykson, R.A.5    Come, C.6
  • 81
    • 77953743748 scopus 로고    scopus 로고
    • ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1
    • E. Sánchez-Tilló, A. Lázaro, R. Torrent, M. Cuatrecasas, E.C. Vaquero, and A. Castells ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1 Oncogene 29 24 2010 3490 3500
    • (2010) Oncogene , vol.29 , Issue.24 , pp. 3490-3500
    • Sánchez-Tilló, E.1    Lázaro, A.2    Torrent, R.3    Cuatrecasas, M.4    Vaquero, E.C.5    Castells, A.6
  • 82
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • A. Cano, M.A. Pérez-Moreno, I. Rodrigo, A. Locascio, M.J. Blanco, and M.G. Del Barrio The transcription factor snail controls epithelial- mesenchymal transitions by repressing E-cadherin expression Nat Cell Biol 2 2 2000 76 83
    • (2000) Nat Cell Biol , vol.2 , Issue.2 , pp. 76-83
    • Cano, A.1    Pérez-Moreno, M.A.2    Rodrigo, I.3    Locascio, A.4    Blanco, M.J.5    Del Barrio, M.G.6
  • 83
    • 51449085561 scopus 로고    scopus 로고
    • Generation of breast cancer stem cells through epithelial-mesenchymal transition
    • A.-P. Morel, M. Lièvre, C. Thomas, G. Hinkal, S. Ansieau, and A. Puisieux Generation of breast cancer stem cells through epithelial-mesenchymal transition PloS one 3 8 2008 e2888
    • (2008) PloS One , vol.3 , Issue.8 , pp. 2888
    • Morel, A.-P.1    Lièvre, M.2    Thomas, C.3    Hinkal, G.4    Ansieau, S.5    Puisieux, A.6
  • 84
    • 78449255989 scopus 로고    scopus 로고
    • MiR-200a regulates epithelial-mesenchymal to stem-like transition via ZEB2 and beta-catenin signaling
    • H. Xia, W.K.C. Cheung, J. Sze, G. Lu, S. Jiang, and H. Yao MiR-200a regulates epithelial-mesenchymal to stem-like transition via ZEB2 and beta-catenin signaling J Biol Chem 285 47 2010 36995 37004
    • (2010) J Biol Chem , vol.285 , Issue.47 , pp. 36995-37004
    • Xia, H.1    Cheung, W.K.C.2    Sze, J.3    Lu, G.4    Jiang, S.5    Yao, H.6
  • 85
    • 33947301272 scopus 로고    scopus 로고
    • Epigenetic signatures of stem-cell identity
    • M. Spivakov, and A.G. Fisher Epigenetic signatures of stem-cell identity Nat Rev Genet 8 4 2007 263 271
    • (2007) Nat Rev Genet , vol.8 , Issue.4 , pp. 263-271
    • Spivakov, M.1    Fisher, A.G.2
  • 86
    • 4644319204 scopus 로고    scopus 로고
    • Stem cells and cancer; The polycomb connection
    • M.E. Valk-Lingbeek, S.W.M. Bruggeman, and M. Van Lohuizen Stem cells and cancer; the polycomb connection Cell 118 4 2004 409 418
    • (2004) Cell , vol.118 , Issue.4 , pp. 409-418
    • Valk-Lingbeek, M.E.1    Bruggeman, S.W.M.2    Van Lohuizen, M.3
  • 88
    • 1342289563 scopus 로고    scopus 로고
    • Bmi1, stem cells, and senescence regulation
    • I.-K. Park, S.J. Morrison, and M.F. Clarke Bmi1, stem cells, and senescence regulation J Clin Invest 113 2 2004 175 179
    • (2004) J Clin Invest , vol.113 , Issue.2 , pp. 175-179
    • Park, I.-K.1    Morrison, S.J.2    Clarke, M.F.3
  • 92
    • 0034256009 scopus 로고    scopus 로고
    • In vitro replication and differentiation of normal human oral keratinocytes
    • M.K. Kang, C. Bibb, M.A. Baluda, O. Rey, and N.H. Park In vitro replication and differentiation of normal human oral keratinocytes Exp Cell Res 258 2 2000 288 297
    • (2000) Exp Cell Res , vol.258 , Issue.2 , pp. 288-297
    • Kang, M.K.1    Bibb, C.2    Baluda, M.A.3    Rey, O.4    Park, N.H.5
  • 93
    • 77953535364 scopus 로고    scopus 로고
    • Analysis of Ki-67 expression in oral squamous cell carcinoma: Why Ki-67 is not a prognostic indicator
    • M.A. Gonzalez-Moles, I. Ruiz-Avila, J.A. Gil-Montoya, F. Esteban, and M. Bravo Analysis of Ki-67 expression in oral squamous cell carcinoma: why Ki-67 is not a prognostic indicator Oral Oncol 46 7 2010 525 530
    • (2010) Oral Oncol , vol.46 , Issue.7 , pp. 525-530
    • Gonzalez-Moles, M.A.1    Ruiz-Avila, I.2    Gil-Montoya, J.A.3    Esteban, F.4    Bravo, M.5
  • 94
    • 73649140239 scopus 로고    scopus 로고
    • Ki-67 expression in non-tumour epithelium adjacent to oral cancer as risk marker for multiple oral tumours
    • M.A. González-Moles, M. Bravo, I. Ruiz-Avila, F. Acebal, J.A. Gil-Montoya, and S. Brener Ki-67 expression in non-tumour epithelium adjacent to oral cancer as risk marker for multiple oral tumours Oral Dis 16 1 2010 68 75
    • (2010) Oral Dis , vol.16 , Issue.1 , pp. 68-75
    • González-Moles, M.A.1    Bravo, M.2    Ruiz-Avila, I.3    Acebal, F.4    Gil-Montoya, J.A.5    Brener, S.6
  • 95
    • 0034292859 scopus 로고    scopus 로고
    • Suprabasal expression of Ki-67 antigen as a marker for the presence and severity of oral epithelial dysplasia
    • M.A. Gonzalez-Moles, I. Ruiz-Avila, A. Rodriguez-Archilla, and I. Martinez-Lara Suprabasal expression of Ki-67 antigen as a marker for the presence and severity of oral epithelial dysplasia Head Neck 22 7 2000 658 661
    • (2000) Head Neck , vol.22 , Issue.7 , pp. 658-661
    • Gonzalez-Moles, M.A.1    Ruiz-Avila, I.2    Rodriguez-Archilla, A.3    Martinez-Lara, I.4
  • 96
    • 0011478490 scopus 로고
    • Three clonal types of keratinocyte with different capacities for multiplication
    • Y. Barrandon, and H. Green Three clonal types of keratinocyte with different capacities for multiplication Proc Natl Acad Sci USA 84 8 1987 2302 2306
    • (1987) Proc Natl Acad Sci USA , vol.84 , Issue.8 , pp. 2302-2306
    • Barrandon, Y.1    Green, H.2
  • 97
    • 25444482608 scopus 로고    scopus 로고
    • Retention of intrinsic stem cell hierarchies in carcinoma-derived cell lines
    • M. Locke, M. Heywood, S. Fawell, and I.C. Mackenzie Retention of intrinsic stem cell hierarchies in carcinoma-derived cell lines Cancer Res 65 19 2005 8944 8950
    • (2005) Cancer Res , vol.65 , Issue.19 , pp. 8944-8950
    • Locke, M.1    Heywood, M.2    Fawell, S.3    Mackenzie, I.C.4
  • 99
    • 0028888316 scopus 로고
    • Stem cell patterning and fate in human epidermis
    • P.H. Jones, S. Harper, and F.M. Watt Stem cell patterning and fate in human epidermis Cell 80 1 1995 83 93
    • (1995) Cell , vol.80 , Issue.1 , pp. 83-93
    • Jones, P.H.1    Harper, S.2    Watt, F.M.3
  • 102
    • 34248529666 scopus 로고    scopus 로고
    • Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line
    • J. Wang, L.-P. Guo, L.-Z. Chen, Y.-X. Zeng, and S.H. Lu Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line Cancer Res 67 8 2007 3716 3724
    • (2007) Cancer Res , vol.67 , Issue.8 , pp. 3716-3724
    • Wang, J.1    Guo, L.-P.2    Chen, L.-Z.3    Zeng, Y.-X.4    Lu, S.H.5
  • 104
    • 40149092373 scopus 로고    scopus 로고
    • Persistence of side population cells with high drug efflux capacity in pancreatic cancer
    • J. Zhou, C.-Y. Wang, T. Liu, B. Wu, F. Zhou, and J.-X. Xiong Persistence of side population cells with high drug efflux capacity in pancreatic cancer World J Gastroenterol 14 6 2008 925 930
    • (2008) World J Gastroenterol , vol.14 , Issue.6 , pp. 925-930
    • Zhou, J.1    Wang, C.-Y.2    Liu, T.3    Wu, B.4    Zhou, F.5    Xiong, J.-X.6
  • 105
    • 38549180030 scopus 로고    scopus 로고
    • Squamous cell cancers contain a side population of stem-like cells that are made chemosensitive by ABC transporter blockade
    • M.R. Loebinger, A. Giangreco, K.R. Groot, L. Prichard, K. Allen, and C. Simpson Squamous cell cancers contain a side population of stem-like cells that are made chemosensitive by ABC transporter blockade Br J Cancer 98 2 2008 380 387
    • (2008) Br J Cancer , vol.98 , Issue.2 , pp. 380-387
    • Loebinger, M.R.1    Giangreco, A.2    Groot, K.R.3    Prichard, L.4    Allen, K.5    Simpson, C.6
  • 106
    • 62949157910 scopus 로고    scopus 로고
    • Side population in oral squamous cell carcinoma possesses tumor stem cell phenotypes
    • P. Zhang, Y. Zhang, L. Mao, Z. Zhang, and W. Chen Side population in oral squamous cell carcinoma possesses tumor stem cell phenotypes Cancer Lett 277 2 2009 227 234
    • (2009) Cancer Lett , vol.277 , Issue.2 , pp. 227-234
    • Zhang, P.1    Zhang, Y.2    Mao, L.3    Zhang, Z.4    Chen, W.5
  • 107
    • 69449094243 scopus 로고    scopus 로고
    • Resistance to cytotoxic chemotherapy-induced apoptosis in side population cells of human oral squamous cell carcinoma cell line Ho-1-N-1
    • T. Yajima, H. Ochiai, T. Uchiyama, N. Takano, T. Shibahara, and T. Azuma Resistance to cytotoxic chemotherapy-induced apoptosis in side population cells of human oral squamous cell carcinoma cell line Ho-1-N-1 Int J Oncol 35 2 2009 273 280
    • (2009) Int J Oncol , vol.35 , Issue.2 , pp. 273-280
    • Yajima, T.1    Ochiai, H.2    Uchiyama, T.3    Takano, N.4    Shibahara, T.5    Azuma, T.6
  • 108
    • 77955372945 scopus 로고    scopus 로고
    • Characterization of side populations in HNSCC: Highly invasive, chemoresistant and abnormal Wnt signaling
    • J. Song, I. Chang, Z. Chen, M. Kang, and C.-Y. Wang Characterization of side populations in HNSCC: highly invasive, chemoresistant and abnormal Wnt signaling PloS One 5 7 2010 e11456
    • (2010) PloS One , vol.5 , Issue.7 , pp. 11456
    • Song, J.1    Chang, I.2    Chen, Z.3    Kang, M.4    Wang, C.-Y.5
  • 109
    • 67349209852 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1 is a putative marker for cancer stem cells in head and neck squamous cancer
    • Y.-C. Chen, Y.-W. Chen, H.-S. Hsu, L.-M. Tseng, P.-I. Huang, and K.-H. Lu Aldehyde dehydrogenase 1 is a putative marker for cancer stem cells in head and neck squamous cancer Biochem Biophys Res Commun 385 3 2009 307 313
    • (2009) Biochem Biophys Res Commun , vol.385 , Issue.3 , pp. 307-313
    • Chen, Y.-C.1    Chen, Y.-W.2    Hsu, H.-S.3    Tseng, L.-M.4    Huang, P.-I.5    Lu, K.-H.6
  • 110
    • 80052273379 scopus 로고    scopus 로고
    • Isolation and characterization of cancer stem-like side population cells in human oral cancer cells
    • S. Yanamoto, G. Kawasaki, S. Yamada, I. Yoshitomi, T. Kawano, and H. Yonezawa Isolation and characterization of cancer stem-like side population cells in human oral cancer cells Oral Oncol 47 9 2011 855 860
    • (2011) Oral Oncol , vol.47 , Issue.9 , pp. 855-860
    • Yanamoto, S.1    Kawasaki, G.2    Yamada, S.3    Yoshitomi, I.4    Kawano, T.5    Yonezawa, H.6
  • 111
    • 0029958876 scopus 로고    scopus 로고
    • Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
    • M.A. Goodell, K. Brose, G. Paradis, A.S. Conner, and R.C. Mulligan Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo J Exp Med 183 4 1996 1797 1806
    • (1996) J Exp Med , vol.183 , Issue.4 , pp. 1797-1806
    • Goodell, M.A.1    Brose, K.2    Paradis, G.3    Conner, A.S.4    Mulligan, R.C.5
  • 113
    • 53749088741 scopus 로고    scopus 로고
    • Identification of side population cells in human hepatocellular carcinoma cell lines with stepwise metastatic potentials
    • G.-M. Shi, Y. Xu, J. Fan, J. Zhou, X.-R. Yang, and S.-J. Qiu Identification of side population cells in human hepatocellular carcinoma cell lines with stepwise metastatic potentials J Cancer Res Clin Oncol 134 11 2008 1155 1163
    • (2008) J Cancer Res Clin Oncol , vol.134 , Issue.11 , pp. 1155-1163
    • Shi, G.-M.1    Xu, Y.2    Fan, J.3    Zhou, J.4    Yang, X.-R.5    Qiu, S.-J.6
  • 114
    • 69849110542 scopus 로고    scopus 로고
    • A side population of cells from a human pancreatic carcinoma cell line harbors cancer stem cell characteristics
    • Y.H. Wang, F. Li, B. Luo, X.H. Wang, H.C. Sun, and S. Liu A side population of cells from a human pancreatic carcinoma cell line harbors cancer stem cell characteristics Neoplasma 56 5 2009 371 378
    • (2009) Neoplasma , vol.56 , Issue.5 , pp. 371-378
    • Wang, Y.H.1    Li, F.2    Luo, B.3    Wang, X.H.4    Sun, H.C.5    Liu, S.6
  • 115
    • 33745924696 scopus 로고    scopus 로고
    • Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties
    • T. Chiba, K. Kita, Y.-W. Zheng, O. Yokosuka, H. Saisho, and A. Iwama Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties Hepatology 44 1 2006 240 251
    • (2006) Hepatology , vol.44 , Issue.1 , pp. 240-251
    • Chiba, T.1    Kita, K.2    Zheng, Y.-W.3    Yokosuka, O.4    Saisho, H.5    Iwama, A.6
  • 116
    • 1642474273 scopus 로고    scopus 로고
    • Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line
    • T. Kondo, T. Setoguchi, and T. Taga Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line Proc Natl Acad Sci USA 101 3 2004 781 786
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.3 , pp. 781-786
    • Kondo, T.1    Setoguchi, T.2    Taga, T.3
  • 117
    • 33744985294 scopus 로고    scopus 로고
    • Characterization of a side population of cancer cells from human gastrointestinal system
    • N. Haraguchi, T. Utsunomiya, H. Inoue, F. Tanaka, K. Mimori, and G.F. Barnard Characterization of a side population of cancer cells from human gastrointestinal system Stem Cells 24 3 2006 506 513
    • (2006) Stem Cells , vol.24 , Issue.3 , pp. 506-513
    • Haraguchi, N.1    Utsunomiya, T.2    Inoue, H.3    Tanaka, F.4    Mimori, K.5    Barnard, G.F.6
  • 118
    • 33746625091 scopus 로고    scopus 로고
    • Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness
    • P.P. Szotek, R. Pieretti-Vanmarcke, P.T. Masiakos, D.M. Dinulescu, D. Connolly, and R. Foster Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness Proc Natl Acad Sci USA 103 30 2006 11154 11159
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.30 , pp. 11154-11159
    • Szotek, P.P.1    Pieretti-Vanmarcke, R.2    Masiakos, P.T.3    Dinulescu, D.M.4    Connolly, D.5    Foster, R.6
  • 120
    • 33745505758 scopus 로고    scopus 로고
    • Human side population keratinocytes exhibit long-term proliferative potential and a specific gene expression profile and can form a pluristratified epidermis
    • G. Larderet, N.O. Fortunel, P. Vaigot, M. Cegalerba, P. Maltère, and O. Zobiri Human side population keratinocytes exhibit long-term proliferative potential and a specific gene expression profile and can form a pluristratified epidermis Stem Cells 24 4 2006 965 974
    • (2006) Stem Cells , vol.24 , Issue.4 , pp. 965-974
    • Larderet, G.1    Fortunel, N.O.2    Vaigot, P.3    Cegalerba, M.4    Maltère, P.5    Zobiri, O.6
  • 121
    • 25444517339 scopus 로고    scopus 로고
    • Identification of novel resident pulmonary stem cells: Form and function of the lung side population
    • S.M. Majka, M.A. Beutz, M. Hagen, A.A. Izzo, N. Voelkel, and K.M. Helm Identification of novel resident pulmonary stem cells: form and function of the lung side population Stem Cells 23 8 2005 1073 1081
    • (2005) Stem Cells , vol.23 , Issue.8 , pp. 1073-1081
    • Majka, S.M.1    Beutz, M.A.2    Hagen, M.3    Izzo, A.A.4    Voelkel, N.5    Helm, K.M.6
  • 122
    • 0344011434 scopus 로고    scopus 로고
    • Distinct populations of forebrain neural stem and progenitor cells can be isolated using side-population analysis
    • M. Kim, and C.M. Morshead Distinct populations of forebrain neural stem and progenitor cells can be isolated using side-population analysis J Neurosci 23 33 2003 10703 10709
    • (2003) J Neurosci , vol.23 , Issue.33 , pp. 10703-10709
    • Kim, M.1    Morshead, C.M.2
  • 123
    • 0037631832 scopus 로고    scopus 로고
    • Hepatic oval cells have the side population phenotype defined by expression of ATP-binding cassette transporter ABCG2/BCRP1
    • K. Shimano, M. Satake, A. Okaya, J. Kitanaka, N. Kitanaka, and M. Takemura Hepatic oval cells have the side population phenotype defined by expression of ATP-binding cassette transporter ABCG2/BCRP1 Am J Pathol 163 1 2003 3 9
    • (2003) Am J Pathol , vol.163 , Issue.1 , pp. 3-9
    • Shimano, K.1    Satake, M.2    Okaya, A.3    Kitanaka, J.4    Kitanaka, N.5    Takemura, M.6
  • 124
    • 78649476631 scopus 로고    scopus 로고
    • Characterization of side population cells from laryngeal cancer cell lines
    • G. Wan, L. Zhou, M. Xie, H. Chen, and J. Tian Characterization of side population cells from laryngeal cancer cell lines Head Neck 32 10 2010 1302 1309
    • (2010) Head Neck , vol.32 , Issue.10 , pp. 1302-1309
    • Wan, G.1    Zhou, L.2    Xie, M.3    Chen, H.4    Tian, J.5
  • 126
    • 54449085703 scopus 로고    scopus 로고
    • CD44s and CD44v6 expression in head and neck epithelia
    • B. Mack, and O. Gires CD44s and CD44v6 expression in head and neck epithelia PloS One 3 10 2008 e3360
    • (2008) PloS One , vol.3 , Issue.10 , pp. 3360
    • Mack, B.1    Gires, O.2
  • 127
    • 0032951368 scopus 로고    scopus 로고
    • Epithelial stem cells in the skin: Definition, markers, localization and functions
    • G. Cotsarelis, P. Kaur, D. Dhouailly, U. Hengge, and J. Bickenbach Epithelial stem cells in the skin: definition, markers, localization and functions Exp Dermatol 8 1 1999 80 88
    • (1999) Exp Dermatol , vol.8 , Issue.1 , pp. 80-88
    • Cotsarelis, G.1    Kaur, P.2    Dhouailly, D.3    Hengge, U.4    Bickenbach, J.5
  • 128
    • 0029773604 scopus 로고    scopus 로고
    • Isolation and characterization of human epidermal stem cells
    • P.H. Jones Isolation and characterization of human epidermal stem cells Clin Sci (Lond) 91 2 1996 141 146
    • (1996) Clin Sci (Lond) , vol.91 , Issue.2 , pp. 141-146
    • Jones, P.H.1
  • 129
    • 0027475345 scopus 로고
    • Integrin expression in normal, hyperplastic, dysplastic, and malignant oral epithelium
    • J. Jones, M. Sugiyama, F.M. Watt, and P.M. Speight Integrin expression in normal, hyperplastic, dysplastic, and malignant oral epithelium J Pathol 169 2 1993 235 243
    • (1993) J Pathol , vol.169 , Issue.2 , pp. 235-243
    • Jones, J.1    Sugiyama, M.2    Watt, F.M.3    Speight, P.M.4
  • 130
    • 0024395197 scopus 로고
    • Fibronectin inhibits the terminal differentiation of human keratinocytes
    • J.C. Adams, and F.M. Watt Fibronectin inhibits the terminal differentiation of human keratinocytes Nature 340 6231 1989 307 309
    • (1989) Nature , vol.340 , Issue.6231 , pp. 307-309
    • Adams, J.C.1    Watt, F.M.2
  • 131
    • 0033621638 scopus 로고    scopus 로고
    • Beta1 integrins regulate keratinocyte adhesion and differentiation by distinct mechanisms
    • L. Levy, S. Broad, D. Diekmann, R.D. Evans, and F.M. Watt Beta1 integrins regulate keratinocyte adhesion and differentiation by distinct mechanisms Mol Biol Cell 11 2 2000 453 466
    • (2000) Mol Biol Cell , vol.11 , Issue.2 , pp. 453-466
    • Levy, L.1    Broad, S.2    Diekmann, D.3    Evans, R.D.4    Watt, F.M.5
  • 133
    • 0032582513 scopus 로고    scopus 로고
    • Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
    • J. Nichols, B. Zevnik, K. Anastassiadis, H. Niwa, D. Klewe-Nebenius, and I. Chambers Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4 Cell 95 3 1998 379 391
    • (1998) Cell , vol.95 , Issue.3 , pp. 379-391
    • Nichols, J.1    Zevnik, B.2    Anastassiadis, K.3    Niwa, H.4    Klewe-Nebenius, D.5    Chambers, I.6
  • 134
    • 0034028901 scopus 로고    scopus 로고
    • Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
    • H. Niwa, J. Miyazaki, and A.G. Smith Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells Nat Genet 24 4 2000 372 376
    • (2000) Nat Genet , vol.24 , Issue.4 , pp. 372-376
    • Niwa, H.1    Miyazaki, J.2    Smith, A.G.3
  • 136
    • 0038143611 scopus 로고    scopus 로고
    • Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
    • I. Chambers, D. Colby, M. Robertson, J. Nichols, S. Lee, and S. Tweedie Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells Cell 113 5 2003 643 655
    • (2003) Cell , vol.113 , Issue.5 , pp. 643-655
    • Chambers, I.1    Colby, D.2    Robertson, M.3    Nichols, J.4    Lee, S.5    Tweedie, S.6
  • 137
    • 0037806031 scopus 로고    scopus 로고
    • The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
    • K. Mitsui, Y. Tokuzawa, H. Itoh, K. Segawa, M. Murakami, and K. Takahashi The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells Cell 113 5 2003 631 642
    • (2003) Cell , vol.113 , Issue.5 , pp. 631-642
    • Mitsui, K.1    Tokuzawa, Y.2    Itoh, H.3    Segawa, K.4    Murakami, M.5    Takahashi, K.6
  • 139
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • L.A. Boyer, T.I. Lee, M.F. Cole, S.E. Johnstone, S.S. Levine, and J.P. Zucker Core transcriptional regulatory circuitry in human embryonic stem cells Cell 122 6 2005 947 956
    • (2005) Cell , vol.122 , Issue.6 , pp. 947-956
    • Boyer, L.A.1    Lee, T.I.2    Cole, M.F.3    Johnstone, S.E.4    Levine, S.S.5    Zucker, J.P.6
  • 140
    • 33645381936 scopus 로고    scopus 로고
    • The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
    • Y.-H. Loh, Q. Wu, J.-L. Chew, V.B. Vega, W. Zhang, and X. Chen The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells Nat Genet 38 4 2006 431 440
    • (2006) Nat Genet , vol.38 , Issue.4 , pp. 431-440
    • Loh, Y.-H.1    Wu, Q.2    Chew, J.-L.3    Vega, V.B.4    Zhang, W.5    Chen, X.6
  • 141
    • 34047169674 scopus 로고    scopus 로고
    • Stem cell marker OCT3/4 in tumor biology and germ cell tumor diagnostics: History and future
    • J. De Jong, and L.H.J. Looijenga Stem cell marker OCT3/4 in tumor biology and germ cell tumor diagnostics: history and future Crit Rev Oncog 12 3-4 2006 171 203
    • (2006) Crit Rev Oncog , vol.12 , Issue.34 , pp. 171-203
    • De Jong, J.1    Looijenga, L.H.J.2
  • 142
    • 77952344846 scopus 로고    scopus 로고
    • The lamina propria of adult human oral mucosa harbors a novel stem cell population
    • K. Marynka-Kalmani, S. Treves, M. Yafee, H. Rachima, Y. Gafni, and M.A. Cohen The lamina propria of adult human oral mucosa harbors a novel stem cell population Stem Cells 28 5 2010 984 995
    • (2010) Stem Cells , vol.28 , Issue.5 , pp. 984-995
    • Marynka-Kalmani, K.1    Treves, S.2    Yafee, M.3    Rachima, H.4    Gafni, Y.5    Cohen, M.A.6
  • 143
    • 79551686424 scopus 로고    scopus 로고
    • Cancer stem cell traits in squamospheres derived from primary head and neck squamous cell carcinomas
    • Y.C. Lim, S.-Y. Oh, Y.Y. Cha, S.-H. Kim, X. Jin, and H. Kim Cancer stem cell traits in squamospheres derived from primary head and neck squamous cell carcinomas Oral Oncol 47 2 2011 83 91
    • (2011) Oral Oncol , vol.47 , Issue.2 , pp. 83-91
    • Lim, Y.C.1    Oh, S.-Y.2    Cha, Y.Y.3    Kim, S.-H.4    Jin, X.5    Kim, H.6
  • 144
    • 0031453534 scopus 로고    scopus 로고
    • AC133, a novel marker for human hematopoietic stem and progenitor cells
    • A.H. Yin, S. Miraglia, E.D. Zanjani, G. Almeida-Porada, M. Ogawa, and A.G. Leary AC133, a novel marker for human hematopoietic stem and progenitor cells Blood 90 12 1997 5002 5012
    • (1997) Blood , vol.90 , Issue.12 , pp. 5002-5012
    • Yin, A.H.1    Miraglia, S.2    Zanjani, E.D.3    Almeida-Porada, G.4    Ogawa, M.5    Leary, A.G.6
  • 145
    • 0031468289 scopus 로고    scopus 로고
    • A novel five-transmembrane hematopoietic stem cell antigen: Isolation, characterization, and molecular cloning
    • S. Miraglia, W. Godfrey, A.H. Yin, K. Atkins, R. Warnke, and J.T. Holden A novel five-transmembrane hematopoietic stem cell antigen: isolation, characterization, and molecular cloning Blood 90 12 1997 5013 5021
    • (1997) Blood , vol.90 , Issue.12 , pp. 5013-5021
    • Miraglia, S.1    Godfrey, W.2    Yin, A.H.3    Atkins, K.4    Warnke, R.5    Holden, J.T.6
  • 146
    • 48249105531 scopus 로고    scopus 로고
    • Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma
    • S.-H. Chiou, C.-C. Yu, C.-Y. Huang, S.-C. Lin, C.-J. Liu, and T.-H. Tsai Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma Clin Cancer Res 14 13 2008 4085 4095
    • (2008) Clin Cancer Res , vol.14 , Issue.13 , pp. 4085-4095
    • Chiou, S.-H.1    Yu, C.-C.2    Huang, C.-Y.3    Lin, S.-C.4    Liu, C.-J.5    Tsai, T.-H.6
  • 147
    • 0030817282 scopus 로고    scopus 로고
    • Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells
    • A. Weigmann, D. Corbeil, A. Hellwig, and W.B. Huttner Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells Proc Natl Acad Sci USA 94 23 1997 12425 12430
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.23 , pp. 12425-12430
    • Weigmann, A.1    Corbeil, D.2    Hellwig, A.3    Huttner, W.B.4
  • 148
    • 0039765237 scopus 로고    scopus 로고
    • The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions
    • D. Corbeil, K. Röper, A. Hellwig, M. Tavian, S. Miraglia, and S.M. Watt The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions J Biol Chem 275 8 2000 5512 5520
    • (2000) J Biol Chem , vol.275 , Issue.8 , pp. 5512-5520
    • Corbeil, D.1    Röper, K.2    Hellwig, A.3    Tavian, M.4    Miraglia, S.5    Watt, S.M.6
  • 151
    • 44849108126 scopus 로고    scopus 로고
    • Expression profiling of CD133+ and CD133- epithelial cells from human prostate
    • C.J. Shepherd, S. Rizzo, I. Ledaki, M. Davies, D. Brewer, and G. Attard Expression profiling of CD133+ and CD133- epithelial cells from human prostate Prostate 68 9 2008 1007 1024
    • (2008) Prostate , vol.68 , Issue.9 , pp. 1007-1024
    • Shepherd, C.J.1    Rizzo, S.2    Ledaki, I.3    Davies, M.4    Brewer, D.5    Attard, G.6
  • 153
    • 76849098162 scopus 로고    scopus 로고
    • A subpopulation of CD133(+) cancer stem-like cells characterized in human oral squamous cell carcinoma confer resistance to chemotherapy
    • Q. Zhang, S. Shi, Y. Yen, J. Brown, J.Q. Ta, and A.D. Le A subpopulation of CD133(+) cancer stem-like cells characterized in human oral squamous cell carcinoma confer resistance to chemotherapy Cancer Lett 289 2 2010 151 160
    • (2010) Cancer Lett , vol.289 , Issue.2 , pp. 151-160
    • Zhang, Q.1    Shi, S.2    Yen, Y.3    Brown, J.4    Ta, J.Q.5    Le, A.D.6
  • 154
    • 33947095683 scopus 로고    scopus 로고
    • CD133, one of the markers of cancer stem cells in Hep-2 cell line
    • L. Zhou, X. Wei, L. Cheng, J. Tian, and J.J. Jiang CD133, one of the markers of cancer stem cells in Hep-2 cell line Laryngoscope 117 3 2007 455 460
    • (2007) Laryngoscope , vol.117 , Issue.3 , pp. 455-460
    • Zhou, L.1    Wei, X.2    Cheng, L.3    Tian, J.4    Jiang, J.J.5
  • 155
    • 58149508462 scopus 로고    scopus 로고
    • In vivo investigation of CD133 as a putative marker of cancer stem cells in Hep-2 cell line
    • X.D. Wei, L. Zhou, L. Cheng, J. Tian, J.J. Jiang, and J. Maccallum In vivo investigation of CD133 as a putative marker of cancer stem cells in Hep-2 cell line Head Neck 31 1 2009 94 101
    • (2009) Head Neck , vol.31 , Issue.1 , pp. 94-101
    • Wei, X.D.1    Zhou, L.2    Cheng, L.3    Tian, J.4    Jiang, J.J.5    Maccallum, J.6
  • 156
    • 0025282411 scopus 로고
    • CD44 is the principal cell surface receptor for hyaluronate
    • A. Aruffo, I. Stamenkovic, M. Melnick, C.B. Underhill, and B. Seed CD44 is the principal cell surface receptor for hyaluronate Cell 61 7 1990 1303 1313
    • (1990) Cell , vol.61 , Issue.7 , pp. 1303-1313
    • Aruffo, A.1    Stamenkovic, I.2    Melnick, M.3    Underhill, C.B.4    Seed, B.5
  • 157
    • 0027065573 scopus 로고
    • Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons
    • G.R. Screaton, M.V. Bell, D.G. Jackson, F.B. Cornelis, U. Gerth, and J.I. Bell Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons Proc Natl Acad Sci USA 89 24 1992 12160 12164
    • (1992) Proc Natl Acad Sci USA , vol.89 , Issue.24 , pp. 12160-12164
    • Screaton, G.R.1    Bell, M.V.2    Jackson, D.G.3    Cornelis, F.B.4    Gerth, U.5    Bell, J.I.6
  • 159
    • 77954901231 scopus 로고    scopus 로고
    • Single-marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase
    • M.R. Clay, M. Tabor, J.H. Owen, T.E. Carey, C.R. Bradford, and G.T. Wolf Single-marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase Head Neck 32 9 2010 1195 1201
    • (2010) Head Neck , vol.32 , Issue.9 , pp. 1195-1201
    • Clay, M.R.1    Tabor, M.2    Owen, J.H.3    Carey, T.E.4    Bradford, C.R.5    Wolf, G.T.6
  • 161
    • 78649648154 scopus 로고    scopus 로고
    • Cucurbitacin i suppressed stem-like property and enhanced radiation-induced apoptosis in head and neck squamous carcinoma-derived CD44(+)ALDH1(+) cells
    • Y.-W. Chen, K.-H. Chen, P.-I. Huang, Y.-C. Chen, G.-Y. Chiou, and W.-L. Lo Cucurbitacin I suppressed stem-like property and enhanced radiation-induced apoptosis in head and neck squamous carcinoma-derived CD44(+)ALDH1(+) cells Mol Cancer Ther 9 11 2010 2879 2892
    • (2010) Mol Cancer Ther , vol.9 , Issue.11 , pp. 2879-2892
    • Chen, Y.-W.1    Chen, K.-H.2    Huang, P.-I.3    Chen, Y.-C.4    Chiou, G.-Y.5    Lo, W.-L.6
  • 162
    • 83555172386 scopus 로고    scopus 로고
    • Frequency of cells expressing CD44, a head and neck cancer stem cell marker: Correlation with tumor aggressiveness
    • B. Joshua, M.J. Kaplan, I. Doweck, R. Pai, I.L. Weissman, and M.E. Prince Frequency of cells expressing CD44, a head and neck cancer stem cell marker: correlation with tumor aggressiveness Head Neck 34 1 2012 42 49
    • (2012) Head Neck , vol.34 , Issue.1 , pp. 42-49
    • Joshua, B.1    Kaplan, M.J.2    Doweck, I.3    Pai, R.4    Weissman, I.L.5    Prince, M.E.6
  • 164
    • 0033794903 scopus 로고    scopus 로고
    • Reduced expression of CD44 variant 9 is related to lymph node metastasis and poor survival in squamous cell carcinoma of tongue
    • S. Sato, M. Miyauchi, T. Takekoshi, M. Zhao, Y. Kudo, and I. Ogawa Reduced expression of CD44 variant 9 is related to lymph node metastasis and poor survival in squamous cell carcinoma of tongue Oral Oncol 36 6 2000 545 549
    • (2000) Oral Oncol , vol.36 , Issue.6 , pp. 545-549
    • Sato, S.1    Miyauchi, M.2    Takekoshi, T.3    Zhao, M.4    Kudo, Y.5    Ogawa, I.6
  • 166
    • 33846517569 scopus 로고    scopus 로고
    • CD44 expression and its relationship with MMP-9, clinicopathological factors and survival in oral squamous cell carcinoma
    • A. Kosunen, R. Pirinen, K. Ropponen, M. Pukkila, J. Kellokoski, and J. Virtaniemi CD44 expression and its relationship with MMP-9, clinicopathological factors and survival in oral squamous cell carcinoma Oral Oncol 43 1 2007 51 59
    • (2007) Oral Oncol , vol.43 , Issue.1 , pp. 51-59
    • Kosunen, A.1    Pirinen, R.2    Ropponen, K.3    Pukkila, M.4    Kellokoski, J.5    Virtaniemi, J.6
  • 168
    • 4143093757 scopus 로고    scopus 로고
    • Invasion and metastasis of oral cancer cells require methylation of E-cadherin and/or degradation of membranous beta-catenin
    • Y. Kudo, S. Kitajima, I. Ogawa, M. Hiraoka, S. Sargolzaei, and M.R. Keikhaee Invasion and metastasis of oral cancer cells require methylation of E-cadherin and/or degradation of membranous beta-catenin Clin Cancer Res 10 16 2004 5455 5463
    • (2004) Clin Cancer Res , vol.10 , Issue.16 , pp. 5455-5463
    • Kudo, Y.1    Kitajima, S.2    Ogawa, I.3    Hiraoka, M.4    Sargolzaei, S.5    Keikhaee, M.R.6
  • 169
    • 17744419979 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase gene superfamily: The 2002 update
    • N.A. Sophos, and V. Vasiliou Aldehyde dehydrogenase gene superfamily: the 2002 update Chem Biol Interact 143-144 2003 5 22
    • (2003) Chem Biol Interact , vol.143-144 , pp. 5-22
    • Sophos, N.A.1    Vasiliou, V.2
  • 170
    • 0030024868 scopus 로고    scopus 로고
    • Induction of cyclophosphamide-resistance by aldehyde-dehydrogenase gene transfer
    • M. Magni, S. Shammah, R. Schiró, W. Mellado, R. Dalla-Favera, and A.M. Gianni Induction of cyclophosphamide-resistance by aldehyde-dehydrogenase gene transfer Blood 87 3 1996 1097 1103
    • (1996) Blood , vol.87 , Issue.3 , pp. 1097-1103
    • Magni, M.1    Shammah, S.2    Schiró, R.3    Mellado, W.4    Dalla-Favera, R.5    Gianni, A.M.6
  • 171
    • 0029685930 scopus 로고    scopus 로고
    • Overexpression of the human aldehyde dehydrogenase class i results in increased resistance to 4-hydroperoxycyclophosphamide
    • J. Moreb, M. Schweder, A. Suresh, and J.R. Zucali Overexpression of the human aldehyde dehydrogenase class I results in increased resistance to 4-hydroperoxycyclophosphamide Cancer Gene Ther 3 1 1996 24 30
    • (1996) Cancer Gene Ther , vol.3 , Issue.1 , pp. 24-30
    • Moreb, J.1    Schweder, M.2    Suresh, A.3    Zucali, J.R.4
  • 172
    • 33746846201 scopus 로고    scopus 로고
    • Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells
    • J.P. Chute, G.G. Muramoto, J. Whitesides, M. Colvin, R. Safi, and N.J. Chao Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells Proc Natl Acad Sci USA 103 31 2006 11707 11712
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.31 , pp. 11707-11712
    • Chute, J.P.1    Muramoto, G.G.2    Whitesides, J.3    Colvin, M.4    Safi, R.5    Chao, N.J.6
  • 173
    • 35848955428 scopus 로고    scopus 로고
    • ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
    • C. Ginestier, M.H. Hur, E. Charafe-Jauffret, F. Monville, J. Dutcher, and M. Brown ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome Cell Stem Cell 1 5 2007 555 567
    • (2007) Cell Stem Cell , vol.1 , Issue.5 , pp. 555-567
    • Ginestier, C.1    Hur, M.H.2    Charafe-Jauffret, E.3    Monville, F.4    Dutcher, J.5    Brown, M.6
  • 174
    • 78649960144 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling
    • J.P. Sullivan, M. Spinola, M. Dodge, M.G. Raso, C. Behrens, and B. Gao Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling Cancer Res 70 23 2010 9937 9948
    • (2010) Cancer Res , vol.70 , Issue.23 , pp. 9937-9948
    • Sullivan, J.P.1    Spinola, M.2    Dodge, M.3    Raso, M.G.4    Behrens, C.5    Gao, B.6
  • 175
    • 78649939527 scopus 로고    scopus 로고
    • Endothelial cell-initiated signaling promotes the survival and self-renewal of cancer stem cells
    • S. Krishnamurthy, Z. Dong, D. Vodopyanov, A. Imai, J.I. Helman, and M.E. Prince Endothelial cell-initiated signaling promotes the survival and self-renewal of cancer stem cells Cancer Res 70 23 2010 9969 9978
    • (2010) Cancer Res , vol.70 , Issue.23 , pp. 9969-9978
    • Krishnamurthy, S.1    Dong, Z.2    Vodopyanov, D.3    Imai, A.4    Helman, J.I.5    Prince, M.E.6
  • 176
    • 79551522569 scopus 로고    scopus 로고
    • Evidence for epithelial-mesenchymal transition in cancer stem cells of head and neck squamous cell carcinoma
    • C. Chen, Y. Wei, M. Hummel, T.K. Hoffmann, M. Gross, and A.M. Kaufmann Evidence for epithelial-mesenchymal transition in cancer stem cells of head and neck squamous cell carcinoma PloS One 6 1 2011 e16466
    • (2011) PloS One , vol.6 , Issue.1 , pp. 16466
    • Chen, C.1    Wei, Y.2    Hummel, M.3    Hoffmann, T.K.4    Gross, M.5    Kaufmann, A.M.6
  • 177
    • 0036108620 scopus 로고    scopus 로고
    • Cadherin and catenin alterations in human cancer
    • K.M. Hajra, and E.R. Fearon Cadherin and catenin alterations in human cancer Genes Chromosomes Cancer 34 3 2002 255 268
    • (2002) Genes Chromosomes Cancer , vol.34 , Issue.3 , pp. 255-268
    • Hajra, K.M.1    Fearon, E.R.2
  • 178
    • 0025818032 scopus 로고
    • Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role
    • K. Vleminckx, L. Vakaet, M. Mareel, W. Fiers, and F. Van Roy Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role Cell 66 1 1991 107 119
    • (1991) Cell , vol.66 , Issue.1 , pp. 107-119
    • Vleminckx, K.1    Vakaet, L.2    Mareel, M.3    Fiers, W.4    Van Roy, F.5
  • 179
    • 0033104577 scopus 로고    scopus 로고
    • Expression of E-cadherin in oral cancer cell lines and its relationship to invasiveness in SCID mice in vivo
    • T. Hoteiya, E. Hayashi, K. Satomura, N. Kamata, and M. Nagayama Expression of E-cadherin in oral cancer cell lines and its relationship to invasiveness in SCID mice in vivo J Oral Pathol Med 28 3 1999 107 111
    • (1999) J Oral Pathol Med , vol.28 , Issue.3 , pp. 107-111
    • Hoteiya, T.1    Hayashi, E.2    Satomura, K.3    Kamata, N.4    Nagayama, M.5
  • 180
    • 84155162962 scopus 로고    scopus 로고
    • Molecular findings in oral premalignant fields: Update on their diagnostic and clinical implications
    • M.A. Gonzalez-Moles, C. Scully, and I. Ruiz-Avila Molecular findings in oral premalignant fields: update on their diagnostic and clinical implications Oral Dis 18 1 2012 40 47
    • (2012) Oral Dis , vol.18 , Issue.1 , pp. 40-47
    • Gonzalez-Moles, M.A.1    Scully, C.2    Ruiz-Avila, I.3
  • 181
    • 0034947205 scopus 로고    scopus 로고
    • Expression of genetic markers in lymph node metastases compared with their primary tumours in head and neck cancer
    • R.P. Takes, R.J. Baatenburg de Jong, K. Wijffels, E. Schuuring, S.V. Litvinov, and J. Hermans Expression of genetic markers in lymph node metastases compared with their primary tumours in head and neck cancer J Pathol 194 3 2001 298 302
    • (2001) J Pathol , vol.194 , Issue.3 , pp. 298-302
    • Takes, R.P.1    Baatenburg De Jong, R.J.2    Wijffels, K.3    Schuuring, E.4    Litvinov, S.V.5    Hermans, J.6
  • 182
    • 0032479321 scopus 로고    scopus 로고
    • E-cadherin regulates anchorage-independent growth and survival in oral squamous cell carcinoma cells
    • S.S. Kantak, and R.H. Kramer E-cadherin regulates anchorage-independent growth and survival in oral squamous cell carcinoma cells J Biol Chem 273 27 1998 16953 16961
    • (1998) J Biol Chem , vol.273 , Issue.27 , pp. 16953-16961
    • Kantak, S.S.1    Kramer, R.H.2
  • 183
    • 84871574817 scopus 로고    scopus 로고
    • Nicotine promotes acquisition of stem cell and epithelial-to-mesenchymal properties in head and neck squamous cell carcinoma
    • M.A. Yu, A. Kiang, J. Wang-Rodriguez, E. Rahimy, M. Haas, and V. Yu Nicotine promotes acquisition of stem cell and epithelial-to-mesenchymal properties in head and neck squamous cell carcinoma PloS One 7 12 2012 e51967
    • (2012) PloS One , vol.7 , Issue.12 , pp. 51967
    • Yu, M.A.1    Kiang, A.2    Wang-Rodriguez, J.3    Rahimy, E.4    Haas, M.5    Yu, V.6
  • 184
    • 78649454767 scopus 로고    scopus 로고
    • The stem cell code in oral epithelial tumorigenesis: "the cancer stem cell shift hypothesis"
    • V. Richard, and M.R. Pillai The stem cell code in oral epithelial tumorigenesis: "the cancer stem cell shift hypothesis" Biochim Biophys Acta 1806 2 2010 146 162
    • (2010) Biochim Biophys Acta , vol.1806 , Issue.2 , pp. 146-162
    • Richard, V.1    Pillai, M.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.