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Volumn 48, Issue 1, 2012, Pages 1-9

The biology of head and neck cancer stem cells

Author keywords

Angiogenesis; EMT; Epithelial mesenchymal transition; Oral cancer; Perivascular niche; Self renewal; Squamous cell carcinoma; Stemness; Tumorigenesis

Indexed keywords

ALDEHYDE DEHYDROGENASE; CD133 ANTIGEN; HERMES ANTIGEN; TUMOR MARKER;

EID: 84855900675     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2011.10.004     Document Type: Article
Times cited : (136)

References (160)
  • 4
    • 14844321323 scopus 로고    scopus 로고
    • Trends in incidence and prognosis for head and neck cancer in the United States: A site-specific analysis of the SEER database
    • DOI 10.1002/ijc.20740
    • A.L. Carvalho, I.N. Nishimoto, J.A. Califano, and L.P. Kowalski Trends in incidence and prognosis for head and neck cancer in the Unite States: a site-specific analysis of the SEER database Int J Cancer 114 5 2005 806 816 (Pubitemid 40344442)
    • (2005) International Journal of Cancer , vol.114 , Issue.5 , pp. 806-816
    • Carvalho, A.L.1    Nishimoto, I.N.2    Califano, J.A.3    Kowalski, L.P.4
  • 6
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • DOI 10.1038/292154a0
    • M.J. Evan, and M.H. Kaufman Establishment in culture of pluripotential cells from mouse embryos Nature 292 1981 154 156 (Pubitemid 11050741)
    • (1981) Nature , vol.292 , Issue.5819 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 7
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • G.R. Martin Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells Proc Natl Acad Sci U S A 78 12 1981 7634 7638 (Pubitemid 12186197)
    • (1981) Proceedings of the National Academy of Sciences of the United States of America , vol.78 , Issue.12 , pp. 7634-7638
    • Martin, G.R.1
  • 9
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • DOI 10.1038/35102167
    • T. Reya, S.J. Morrison, M.F. Clarke, and I.L. Weissman Stem cells, cancer, and cancer stem cells Nature 414 2001 105 111 (Pubitemid 33041634)
    • (2001) Nature , vol.414 , Issue.6859 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 10
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • DOI 10.1038/nm0797-730
    • D. Bonnet, and J.E. Dick Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell Nat Med 3 7 1997 730 737 (Pubitemid 27298715)
    • (1997) Nature Medicine , vol.3 , Issue.7 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 12
    • 35848964790 scopus 로고    scopus 로고
    • Breast tumor heterogeneity: Cancer stem cells or clonal evolution?
    • L.L. Campbell, and K. Polyak Breast tumor heterogeneity: cancer stem cells or clonal evolution? Cell Cycle 6 19 2007 2332 2338 (Pubitemid 350058682)
    • (2007) Cell Cycle , vol.6 , Issue.19 , pp. 2332-2338
    • Campbell, L.L.1    Polyak, K.2
  • 13
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • P.C. Nowell The clonal evolution of tumor cell populations Science 194 1976 23 28
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 14
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • E.R. Fearon, and B. Vogelstein A genetic model for colorectal tumorigenesis Cell 61 5 1990 759 767
    • (1990) Cell , vol.61 , Issue.5 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 17
    • 34250306257 scopus 로고    scopus 로고
    • Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells
    • DOI 10.1158/0008-5472.CAN-06-3557
    • M.M. Ho, A.V. Ng, S. Lam, and J.Y. Hung Side population in human lung cancer lines and tumors is enriched with stem-like cancer cells Cancer Res 67 10 2007 4827 4833 (Pubitemid 46910191)
    • (2007) Cancer Research , vol.67 , Issue.10 , pp. 4827-4833
    • Ho, M.M.1    Ng, A.V.2    Lam, S.3    Hung, J.Y.4
  • 19
    • 28244472369 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic prostate cancer stem cells
    • DOI 10.1158/0008-5472.CAN-05-2018
    • A.T. Collins, P.A. Berry, C. Hyde, M.J. Stower, and N.J. Maitland Prospective identification of tumourigenic prostate cancer stem cells Cancer Res 65 23 2005 10946 10951 (Pubitemid 41713363)
    • (2005) Cancer Research , vol.65 , Issue.23 , pp. 10946-10951
    • Collins, A.T.1    Berry, P.A.2    Hyde, C.3    Stower, M.J.4    Maitland, N.J.5
  • 20
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • DOI 10.1038/nature05372, PII NATURE05372
    • C.A. O'Brien, A. Pollett, S. Gallinger, and J.E. Dick A human colon cancer cell capable of initiating tumour growth in immunodeficient mice Nature 445 2007 106 110 (Pubitemid 46067310)
    • (2007) Nature , vol.445 , Issue.7123 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3    Dick, J.E.4
  • 22
    • 34548455927 scopus 로고    scopus 로고
    • Distinct Populations of Cancer Stem Cells Determine Tumor Growth and Metastatic Activity in Human Pancreatic Cancer
    • DOI 10.1016/j.stem.2007.06.002, PII S1934590907000665
    • P.C. Hermann, S.L. Huber, T. Herrler, A. Aicher, J.W. Ellwart, and M. Guba Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer Cell Stem Cell 1 3 2007 313 323 (Pubitemid 47355323)
    • (2007) Cell Stem Cell , vol.1 , Issue.3 , pp. 313-323
    • Hermann, P.C.1    Huber, S.L.2    Herrler, T.3    Aicher, A.4    Ellwart, J.W.5    Guba, M.6    Bruns, C.J.7    Heeschen, C.8
  • 26
    • 78650966288 scopus 로고    scopus 로고
    • CXCR6, a newly defined biomarker of tissue-specific stem cell asymmetric self-renewal, identifies more aggressive human melanoma cancer stem cells
    • R. Taghazideh, M. Noh, Y.H. Huh, E. Ciusani, L. Sigalotti, and M. Maio CXCR6, a newly defined biomarker of tissue-specific stem cell asymmetric self-renewal, identifies more aggressive human melanoma cancer stem cells PLoS One 5 12 2010 e15183
    • (2010) PLoS One , vol.5 , Issue.12 , pp. 15183
    • Taghazideh, R.1    Noh, M.2    Huh, Y.H.3    Ciusani, E.4    Sigalotti, L.5    Maio, M.6
  • 27
    • 79954617310 scopus 로고    scopus 로고
    • Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth
    • G. Civenni, A. Walter, N. Kobert, D. Mihic-Probst, M. Zipser, and B. Belloni Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth Cancer Res 71 8 2011 3098 3119
    • (2011) Cancer Res , vol.71 , Issue.8 , pp. 3098-3119
    • Civenni, G.1    Walter, A.2    Kobert, N.3    Mihic-Probst, D.4    Zipser, M.5    Belloni, B.6
  • 28
    • 77954901231 scopus 로고    scopus 로고
    • Single-marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase
    • M.R. Clay, M. Tabor, J.H. Owen, T.E. Carey, C.R. Bradford, and G.T. Wolf Single-marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase Head Neck 32 9 2010 1195 1201
    • (2010) Head Neck , vol.32 , Issue.9 , pp. 1195-1201
    • Clay, M.R.1    Tabor, M.2    Owen, J.H.3    Carey, T.E.4    Bradford, C.R.5    Wolf, G.T.6
  • 29
    • 78649939527 scopus 로고    scopus 로고
    • Endothelial cell-initiated signaling promotes the survival and self-renewal of cancer stem cells
    • S. Krishnamurthy, Z. Dong, D. Vodopyanov, A. Imai, J.I. Helman, and M.E. Prince Endothelial cell-initiated signaling promotes the survival and self-renewal of cancer stem cells Cancer Res 70 23 2010 9969 9978
    • (2010) Cancer Res , vol.70 , Issue.23 , pp. 9969-9978
    • Krishnamurthy, S.1    Dong, Z.2    Vodopyanov, D.3    Imai, A.4    Helman, J.I.5    Prince, M.E.6
  • 30
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
    • J.E. Visvader, and G.J. Lindeman Cancer stem cells in solid tumours: accumulating evidence and unresolved questions Nat Rev Cancer 8 10 2008 755 768
    • (2008) Nat Rev Cancer , vol.8 , Issue.10 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 31
    • 0031044215 scopus 로고    scopus 로고
    • Viable offspring derived from fetal and adult mammalian cells
    • DOI 10.1038/385810a0
    • I. Wilmut, A.E. Schnieke, J. Mcwhir, A.J. Kind, and K.H. Campbell Viable offspring derived from fetal and adult mammalian cells Nature 385 1997 810 813 (Pubitemid 27106068)
    • (1997) Nature , vol.385 , Issue.6619 , pp. 810-813
    • Wilmut, I.1    Schnieke, A.E.2    McWhir, J.3    Kind, A.J.4    Campbell, K.H.S.5
  • 32
    • 0035797898 scopus 로고    scopus 로고
    • Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells
    • DOI 10.1016/S0960-9822(01)00459-6
    • M. Tata, Y. Takahama, K. Abe, N. Nakatsuji, and T. Tada Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells Curr Biol 11 19 2001 1553 1558 (Pubitemid 32931020)
    • (2001) Current Biology , vol.11 , Issue.19 , pp. 1553-1558
    • Tada, M.1    Takahama, Y.2    Abe, K.3    Nakatsuji, N.4    Tada, T.5
  • 33
    • 23944457397 scopus 로고    scopus 로고
    • Developmental Biology: Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells
    • DOI 10.1126/science.1116447
    • C.A. Cowan, J. Atienza, D.A. Melton, and K. Eggan Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells Science 309 2005 1369 1373 (Pubitemid 41209363)
    • (2005) Science , vol.309 , Issue.5739 , pp. 1369-1373
    • Cowan, C.A.1    Atienza, J.2    Melton, D.A.3    Eggan, K.4
  • 34
    • 33747195353 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
    • DOI 10.1016/j.cell.2006.07.024, PII S0092867406009767
    • K. Takahashi, and S. Yamanaka Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 126 4 2006 663 676 (Pubitemid 44233629)
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 35
    • 36248966518 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
    • DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
    • K. Takahashi, K. Tanabe, M. Ohnuki, M. Narita, T. Ichisaka, and K. Tomoda Induction of pluripotent stem cells from adult human fibroblasts by defined factors Cell 131 5 2007 861 872 (Pubitemid 350138099)
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 37
    • 0345059767 scopus 로고    scopus 로고
    • Applying the principles of stem-cell biology to cancer
    • R. Pardal, M.F. Clarke, and S.J. Morrison Applying the principles of stem-cell biology to cancer Nat Rev Cancer 3 12 2003 895 902 (Pubitemid 37500174)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.12 , pp. 895-902
    • Pardal, R.1    Clarke, M.F.2    Morrison, S.J.3
  • 38
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling in development and disease
    • H. Clevers Wnt/β-catenin signaling in development and disease Cell 127 3 2006 469 480
    • (2006) Cell , vol.127 , Issue.3 , pp. 469-480
    • Clevers, H.1
  • 39
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • DOI 10.1038/nature03319
    • T. Reya, and H. Clevers Wnt signaling in stem cells and cancer Nature 434 2005 843 850 (Pubitemid 40558990)
    • (2005) Nature , vol.434 , Issue.7035 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 43
    • 70350641014 scopus 로고    scopus 로고
    • SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
    • A.J. Bass, H. Watanabe, C.H. Mermel, S. Yu, S. Perner, and R.G. Verhaak SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas Nat Genet 41 11 2009 1238 1242
    • (2009) Nat Genet , vol.41 , Issue.11 , pp. 1238-1242
    • Bass, A.J.1    Watanabe, H.2    Mermel, C.H.3    Yu, S.4    Perner, S.5    Verhaak, R.G.6
  • 44
    • 77949360656 scopus 로고    scopus 로고
    • Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung
    • P. Yuan, H. Kadara, C. Behrens, X. Tang, D. Woods, and L.M. Solis Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung PLoS One 5 2 2010 e9112
    • (2010) PLoS One , vol.5 , Issue.2 , pp. 9112
    • Yuan, P.1    Kadara, H.2    Behrens, C.3    Tang, X.4    Woods, D.5    Solis, L.M.6
  • 46
    • 76749112922 scopus 로고    scopus 로고
    • NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer
    • S.S. Sikandar, K.T. Pate, S. Anderson, D. Dizon, R.A. Edwards, and M.L. Waterman NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer Cancer Res 70 4 2010 1469 1478
    • (2010) Cancer Res , vol.70 , Issue.4 , pp. 1469-1478
    • Sikandar, S.S.1    Pate, K.T.2    Anderson, S.3    Dizon, D.4    Edwards, R.A.5    Waterman, M.L.6
  • 47
    • 80052177544 scopus 로고    scopus 로고
    • Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1
    • N. Agrawal, M.J. Frederick, C.R. Pickering, C. Bettegowda, K. Chang, and R.J. Li Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1 Science 333 2011 1154 1157
    • (2011) Science , vol.333 , pp. 1154-1157
    • Agrawal, N.1    Frederick, M.J.2    Pickering, C.R.3    Bettegowda, C.4    Chang, K.5    Li, R.J.6
  • 49
    • 0346724511 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and its implications for fibrosis
    • DOI 10.1172/JCI200320530
    • R. Kalluri, and E.G. Neilson Epithelial-mesenchymal transition and its implications for fibrosis J Clin Invest 112 12 2003 1776 1784 (Pubitemid 38063698)
    • (2003) Journal of Clinical Investigation , vol.112 , Issue.12 , pp. 1776-1784
    • Kalluri, R.1    Neilson, E.G.2
  • 50
    • 0242413065 scopus 로고    scopus 로고
    • Mechanisms, mechanics and function of epithelial-mesenchymal transitions in early development
    • DOI 10.1016/j.mod.2003.06.005
    • D. Shook, and R. Keller Mechanisms, mechanics and function of epithelial-mesenchymal transition in early development Mech Dev 120 11 2003 1351 1383 (Pubitemid 37421168)
    • (2003) Mechanisms of Development , vol.120 , Issue.11 , pp. 1351-1383
    • Shook, D.1    Keller, R.2
  • 51
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • J.P. Thiery Epithelial-mesenchymal transitions in tumour progression Nat Rev Cancer 2 6 2002 442 454
    • (2002) Nat Rev Cancer , vol.2 , Issue.6 , pp. 442-454
    • Thiery, J.P.1
  • 52
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • J.P. Thiery, H. Acloque, Huang.R. YJ, and M.A. Nieto Epithelial- mesenchymal transitions in development and disease Cell 139 5 2009 871 890
    • (2009) Cell , vol.139 , Issue.5 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Yj, Huang.R.3    Nieto, M.A.4
  • 53
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • R. Kalluri, and R.A. Weinberg The basics of epithelial-mesenchymal transition J Clin Invest 119 6 2009 1420 1428
    • (2009) J Clin Invest , vol.119 , Issue.6 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 54
    • 33744808249 scopus 로고    scopus 로고
    • Molecular pathways regulating EGF-induced epithelial-mesenchymal transition in human ovarian surface epithelium
    • N. Ahmed, S. Maines-Bandiera, M.A. Quinn, W.G. Unger, S. Dedhar, and N. Auersperg Molecular pathways regulating EGF-induced epithelial-mesenchymal transition in human ovarian surface epithelium Am J Physiol Cell Physiol 290 6 2006 C1532 C1542
    • (2006) Am J Physiol Cell Physiol , vol.290 , Issue.6
    • Ahmed, N.1    Maines-Bandiera, S.2    Quinn, M.A.3    Unger, W.G.4    Dedhar, S.5    Auersperg, N.6
  • 55
    • 56749095797 scopus 로고    scopus 로고
    • Transcriptional regulation of cell polarity in EMT and cancer
    • G. Moreno-Bueno, F. Portillo, and A. Cano Transcriptional regulation of cell polarity in EMT and cancer Oncogene 27 55 2008 6958 6969
    • (2008) Oncogene , vol.27 , Issue.55 , pp. 6958-6969
    • Moreno-Bueno, G.1    Portillo, F.2    Cano, A.3
  • 56
    • 45549105086 scopus 로고    scopus 로고
    • The transcription factor snail represses Crumbs3 expression and disrupts apico-basal polarity complexes
    • DOI 10.1038/onc.2008.9, PII ONC20089
    • E.L. Whiteman, C.J. Liu, E.R. Fearon, and B. Margolis The transcription factor snail represses Crumbs3 expression and disrupts apico-basal polarity complexes Oncogene 27 27 2008 3875 3879 (Pubitemid 351862065)
    • (2008) Oncogene , vol.27 , Issue.27 , pp. 3875-3879
    • Whiteman, E.L.1    Liu, C.-J.2    Fearon, E.R.3    Margolis, B.4
  • 57
    • 0032510494 scopus 로고    scopus 로고
    • A causal role for E-cadherin in the transition from adenoma to carcinoma
    • DOI 10.1038/32433
    • A.K. Perl, P. Wilgenbus, U. Dahl, H. Semb, and G. Christofori A causal role for E-cadherin in the transition from adenoma to carcinoma Nature 392 1998 190 193 (Pubitemid 28162793)
    • (1998) Nature , vol.392 , Issue.6672 , pp. 190-193
    • Peri, A.-K.1    Wilgenbus, P.2    Dahl, U.3    Semb, H.4    Christofori, G.5
  • 58
    • 0033789680 scopus 로고    scopus 로고
    • The transcription factor snail is a repressor of E-cadherin gene expression in the epithelial tumour cells
    • E. Batlle, E. Sancho, C. Franci, D. Dominguez, M. Monfar, and J. Baulida The transcription factor snail is a repressor of E-cadherin gene expression in the epithelial tumour cells Nat Cell Biol 2 2 2000 84 89
    • (2000) Nat Cell Biol , vol.2 , Issue.2 , pp. 84-89
    • Batlle, E.1    Sancho, E.2    Franci, C.3    Dominguez, D.4    Monfar, M.5    Baulida, J.6
  • 61
    • 77953743748 scopus 로고    scopus 로고
    • ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1
    • E. Sánchez-Tilló, A. Lázaro, R. Torrent, M. Cuatrecasas, E.C. Vaquero, and A. Castells ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1 Oncogene 29 24 2010 3490 3500
    • (2010) Oncogene , vol.29 , Issue.24 , pp. 3490-3500
    • Sánchez-Tilló, E.1    Lázaro, A.2    Torrent, R.3    Cuatrecasas, M.4    Vaquero, E.C.5    Castells, A.6
  • 62
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • A. Cano, M.A. Pérez-Moreno, I. Rodrigo, A. Locascio, M.J. Blanco, and M.G. del Barrio The transcription factor snail controls epithelial- mesenchymal transitions by repressing E-cadherin expression Nat Cell Biol 2 2 2000 76 83
    • (2000) Nat Cell Biol , vol.2 , Issue.2 , pp. 76-83
    • Cano, A.1    Pérez-Moreno, M.A.2    Rodrigo, I.3    Locascio, A.4    Blanco, M.J.5    Del Barrio, M.G.6
  • 63
    • 33847327128 scopus 로고    scopus 로고
    • Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines
    • A.D. Yang, F. Fan, E.R. Camp, G. van Buren, W. Liu, and R. Somcio Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines Clin Cancer Res 12 14 2006 4147 4153
    • (2006) Clin Cancer Res , vol.12 , Issue.14 , pp. 4147-4153
    • Yang, A.D.1    Fan, F.2    Camp, E.R.3    Van Buren, G.4    Liu, W.5    Somcio, R.6
  • 64
    • 33947192053 scopus 로고    scopus 로고
    • Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel
    • DOI 10.1158/0008-5472.CAN-06-1479
    • G.Z. Cheng, J. Chan, Q. Wang, W. Zhang, C.D. Sun, and L.H. Wang Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion and resistance to paclitaxel Cancer Res 67 5 2007 1979 1987 (Pubitemid 46424214)
    • (2007) Cancer Research , vol.67 , Issue.5 , pp. 1979-1987
    • Cheng, G.Z.1    Chan, J.2    Wang, Q.3    Zhang, W.4    Sun, C.D.5    Wang, L.-H.6
  • 65
    • 65249155400 scopus 로고    scopus 로고
    • Twist1-mediated adriamycin-induced epithelial-mesenchymal transition relates to multidrug resistance and invasive potential in breast cancer cells
    • Q.Q. Li, J.D. Xu, W.J. Wang, X.X. Cao, Q. Chen, and F. Tang Twist1-mediated adriamycin-induced epithelial-mesenchymal transition relates to multidrug resistance and invasive potential in breast cancer cells Clin Cancer Res 15 8 2009 2657 2665
    • (2009) Clin Cancer Res , vol.15 , Issue.8 , pp. 2657-2665
    • Li, Q.Q.1    Xu, J.D.2    Wang, W.J.3    Cao, X.X.4    Chen, Q.5    Tang, F.6
  • 66
    • 37049007672 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition events during human embryonic stem cell differentiation
    • DOI 10.1158/0008-5472.CAN-07-2253
    • A.M. Eastham, H. Spencer, F. Soncin, S. Ritson, C.L. Merry, and P.L. Stem Epithelial-mesenchymal transition events during human embryonic stem cell differentiation Cancer Res 67 23 2007 11254 11262 (Pubitemid 350248551)
    • (2007) Cancer Research , vol.67 , Issue.23 , pp. 11254-11262
    • Eastham, A.M.1    Spencer, H.2    Soncin, F.3    Ritson, S.4    Merry, C.L.R.5    Stern, P.L.6    Ward, C.M.7
  • 68
    • 66149131111 scopus 로고    scopus 로고
    • Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells
    • M. Santisteban, J.M. Reiman, M.K. Asiedu, M.D. Behrens, A. Nassar, and K.R. Kalli Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells Cancer Res 69 7 2009 2887 2895
    • (2009) Cancer Res , vol.69 , Issue.7 , pp. 2887-2895
    • Santisteban, M.1    Reiman, J.M.2    Asiedu, M.K.3    Behrens, M.D.4    Nassar, A.5    Kalli, K.R.6
  • 69
    • 51449085561 scopus 로고    scopus 로고
    • Generation of breast cancer stem cells through epithelial-mesenchymal transition
    • A.P. Morel, M. Livre, C. Thomas, G. Hinkal, S. Ansieau, and A. Puisieux Generation of breast cancer stem cells through epithelial-mesenchymal transition PLoS One 3 8 2008 e2888
    • (2008) PLoS One , vol.3 , Issue.8 , pp. 2888
    • Morel, A.P.1    Livre, M.2    Thomas, C.3    Hinkal, G.4    Ansieau, S.5    Puisieux, A.6
  • 70
    • 78449255989 scopus 로고    scopus 로고
    • MiR-200a regulates epithelial-mesenchymal to stem-like transition via ZEB2 and β-catenin signaling
    • H. Xia, W.K. Cheung, J. Sze, G. Lu, S. Jiang, and H. Yao MiR-200a regulates epithelial-mesenchymal to stem-like transition via ZEB2 and β-catenin signaling J Biol Chem 285 47 2010 36995 37004
    • (2010) J Biol Chem , vol.285 , Issue.47 , pp. 36995-37004
    • Xia, H.1    Cheung, W.K.2    Sze, J.3    Lu, G.4    Jiang, S.5    Yao, H.6
  • 71
    • 33947301272 scopus 로고    scopus 로고
    • Epigenetic signatures of stem-cell identity
    • DOI 10.1038/nrg2046, PII NRG2046
    • M. Spivakov, and A.G. Fisher Epigenetic signatures of stem-cell identity Nat Rev Cancer 8 4 2007 263 271 (Pubitemid 46439288)
    • (2007) Nature Reviews Genetics , vol.8 , Issue.4 , pp. 263-271
    • Spivakov, M.1    Fisher, A.G.2
  • 72
    • 4644319204 scopus 로고    scopus 로고
    • Stem cells and cancer: The polycomb connection
    • DOI 10.1016/j.cell.2004.08.005, PII S0092867404007457
    • M.E. Valk-lingbeek, S.W. Bruggeman, and M. Van Lohuizen Stem cells and cancer; the polycomb connection Cell 118 4 2004 409 418 (Pubitemid 39485661)
    • (2004) Cell , vol.118 , Issue.4 , pp. 409-418
    • Valk-Lingbeek, M.E.1    Bruggeman, S.W.M.2    Van Lohuizen, M.3
  • 75
    • 77957583439 scopus 로고    scopus 로고
    • Bmi-1 is essential in twist1-induced epithelial-mesenchymal transition
    • M.H. Yang, D.S. Hsu, H.W. Wang, H.J. Wang, H.Y. Lan, and W.H. Yang Bmi-1 is essential in twist1-induced epithelial-mesenchymal transition Nat Cell Biol 12 10 2010 982 992
    • (2010) Nat Cell Biol , vol.12 , Issue.10 , pp. 982-992
    • Yang, M.H.1    Hsu, D.S.2    Wang, H.W.3    Wang, H.J.4    Lan, H.Y.5    Yang, W.H.6
  • 76
    • 72849130207 scopus 로고    scopus 로고
    • The polycomb group protein Bmi-1 repressed the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelia cells
    • L.B. Song, J. Li, W.T. Liao, Y. Feng, C.P. Yu, and L.J. Hu The polycomb group protein Bmi-1 repressed the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelia cells J Clin Invest 119 12 2009 3626 3636
    • (2009) J Clin Invest , vol.119 , Issue.12 , pp. 3626-3636
    • Song, L.B.1    Li, J.2    Liao, W.T.3    Feng, Y.4    Yu, C.P.5    Hu, L.J.6
  • 78
    • 77950867351 scopus 로고    scopus 로고
    • TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma
    • M.E. Kupferman, T. Jiffar, A. EI-Naggar, T. Yilmaz, G. Zhou, and T. Xie TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma Oncogene 29 14 2010 2047 2059
    • (2010) Oncogene , vol.29 , Issue.14 , pp. 2047-2059
    • Kupferman, M.E.1    Jiffar, T.2    Ei-Naggar, A.3    Yilmaz, T.4    Zhou, G.5    Xie, T.6
  • 79
    • 79551522569 scopus 로고    scopus 로고
    • Evidence for epithelial-mesenchymal transition in cancer stem cells of head and neck squamous cell carcinoma
    • C. Chen, Y. Wei, M. Hummel, T.K. Hoffmann, M. Gross, and A.M. Kaufmann Evidence for epithelial-mesenchymal transition in cancer stem cells of head and neck squamous cell carcinoma Plos One 6 1 2011 e16466
    • (2011) Plos One , vol.6 , Issue.1 , pp. 16466
    • Chen, C.1    Wei, Y.2    Hummel, M.3    Hoffmann, T.K.4    Gross, M.5    Kaufmann, A.M.6
  • 80
    • 39149144034 scopus 로고    scopus 로고
    • Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life
    • DOI 10.1016/j.cell.2008.01.038, PII S0092867408001396
    • S.J. Morrison, and A.C. Spradling Stem cells and niches: Mechanisms that promote stem cell maintenance throughout life Cell 132 4 2008 598 611 (Pubitemid 351253690)
    • (2008) Cell , vol.132 , Issue.4 , pp. 598-611
    • Morrison, S.J.1    Spradling, A.C.2
  • 82
    • 33846003811 scopus 로고    scopus 로고
    • Hit 'Em Where They Live: Targeting the Cancer Stem Cell Niche
    • DOI 10.1016/j.ccr.2006.12.007, PII S1535610806003734
    • Z.J. Yang, and R.J. Wechsler-Reya Hit 'em where they live: targeting the cancer stem cell niche Cancer Cell 11 1 2007 3 5 (Pubitemid 46054521)
    • (2007) Cancer Cell , vol.11 , Issue.1 , pp. 3-5
    • Yang, Z.-J.1    Wechsler-Reya, R.J.2
  • 83
    • 33645739790 scopus 로고    scopus 로고
    • Tumor stroma and regulation of cancer development
    • T.D. TIsty, and L.M. Coussens Tumor stroma and regulation of cancer development Annu Rev Pathol 1 2006 119 150
    • (2006) Annu Rev Pathol , vol.1 , pp. 119-150
    • Tisty, T.D.1    Coussens, L.M.2
  • 85
    • 76749124316 scopus 로고    scopus 로고
    • VEGF-dependent tumor angiogenesis requires inverse and reciprocal regulation of VEGFR1 and VEGFR2
    • Z. Zhang, K.G. Neiva, M.W. Lingen, L.M. Ellis, and J.E. Nör VEGF-dependent tumor angiogenesis requires inverse and reciprocal regulation of VEGFR1 and VEGFR2 Cell Death Differ 17 3 2010 499 512
    • (2010) Cell Death Differ , vol.17 , Issue.3 , pp. 499-512
    • Zhang, Z.1    Neiva, K.G.2    Lingen, M.W.3    Ellis, L.M.4    Nör, J.E.5
  • 86
    • 66449127943 scopus 로고    scopus 로고
    • Crosstalk initiated by endothelial cells enhances migration and inhibits anoikis of squamous cell carcinoma cells through STAT/Akt/ERK signaling
    • K.G. Neiva, Z. Zhang, M. Miyazawa, K.A. Warner, E. Karl, and J.E. Nör Crosstalk initiated by endothelial cells enhances migration and inhibits anoikis of squamous cell carcinoma cells through STAT/Akt/ERK signaling Neoplasia 11 6 2009 583 593
    • (2009) Neoplasia , vol.11 , Issue.6 , pp. 583-593
    • Neiva, K.G.1    Zhang, Z.2    Miyazawa, M.3    Warner, K.A.4    Karl, E.5    Nör, J.E.6
  • 87
    • 0032582513 scopus 로고    scopus 로고
    • Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
    • DOI 10.1016/S0092-8674(00)81769-9
    • J. Nichols, B. Zevnik, K. Anastassiadis, H. Niwa, D. Klewe-Nebenius, and I. Chambers Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4 Cell 95 3 1998 379 391 (Pubitemid 28507326)
    • (1998) Cell , vol.95 , Issue.3 , pp. 379-391
    • Nichols, J.1    Zevnik, B.2    Anastassiadis, K.3    Niwa, H.4    Klewe-Nebenius, D.5    Chambers, I.6    Scholer, H.7    Smith, A.8
  • 88
    • 0034028901 scopus 로고    scopus 로고
    • Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
    • DOI 10.1038/74199
    • H. Niwa, J. Miyazaki, and A.G. Smith Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells Nat Genet 24 4 2000 372 376 (Pubitemid 30187435)
    • (2000) Nature Genetics , vol.24 , Issue.4 , pp. 372-376
    • Niwa, H.1    Miyazaki, J.-I.2    Smith, A.G.3
  • 90
    • 0038143611 scopus 로고    scopus 로고
    • Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
    • DOI 10.1016/S0092-8674(03)00392-1
    • I. Chambers, D. Colby, M. Robretson, J. Nichols, S. Lee, and S. Tweedie Functional expression cloning of nanog a pluripotency sustaining factor in embryonic stem cells Cell 113 5 2003 643 655 (Pubitemid 36694189)
    • (2003) Cell , vol.113 , Issue.5 , pp. 643-655
    • Chambers, I.1    Colby, D.2    Robertson, M.3    Nichols, J.4    Lee, S.5    Tweedie, S.6    Smith, A.7
  • 91
    • 0037806031 scopus 로고    scopus 로고
    • The homeoprotein nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
    • DOI 10.1016/S0092-8674(03)00393-3
    • K. Mitsui, Y. Tokuzawa, H. Itoh, K. Segawa, M. Murakami, and K. Takahashi The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells Cell 113 5 2003 631 642 (Pubitemid 36694188)
    • (2003) Cell , vol.113 , Issue.5 , pp. 631-642
    • Mitsui, K.1    Tokuzawa, Y.2    Itoh, H.3    Segawa, K.4    Murakami, M.5    Takahashi, K.6    Maruyama, M.7    Maeda, M.8    Yamanaka, S.9
  • 93
    • 33645381936 scopus 로고    scopus 로고
    • The Oct4 and nanog transcription network regulates pluripotency in mouse embryonic stem cells
    • Y.H. Loh, Q. Wu, J.L. Chew, V.B. Vega, W. Zhang, and X. Chen The Oct4 and nanog transcription network regulates pluripotency in mouse embryonic stem cells Nat Genet 38 4 2006 431 440
    • (2006) Nat Genet , vol.38 , Issue.4 , pp. 431-440
    • Loh, Y.H.1    Wu, Q.2    Chew, J.L.3    Vega, V.B.4    Zhang, W.5    Chen, X.6
  • 94
    • 77952344846 scopus 로고    scopus 로고
    • The lamina propria of adult human oral mucosa harbors a novel stem cell population
    • K. Marynka-Kalmani, S. Treves, M. Yafee, H. Rachima, Y. Gafni, and M.A. Cohen The lamina propria of adult human oral mucosa harbors a novel stem cell population Stem cell 28 5 2010 984 995
    • (2010) Stem Cell , vol.28 , Issue.5 , pp. 984-995
    • Marynka-Kalmani, K.1    Treves, S.2    Yafee, M.3    Rachima, H.4    Gafni, Y.5    Cohen, M.A.6
  • 95
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
    • DOI 10.1038/ng.127, PII NG127
    • I. Ben-Porath, M.W. Thomson, V.J. Carey, R. Ge, G.W. Bell, and A. Regev An embryonic stem cell-like gene expression signature in poorly differentiated human tumors Nat Genet 40 5 2008 499 507 (Pubitemid 351601215)
    • (2008) Nature Genetics , vol.40 , Issue.5 , pp. 499-507
    • Ben-Porath, I.1    Thomson, M.W.2    Carey, V.J.3    Ge, R.4    Bell, G.W.5    Regev, A.6    Weinberg, R.A.7
  • 96
    • 79551686424 scopus 로고    scopus 로고
    • Cancer stem cell traits in squamouspheres derived from primary head and neck squamous cell carcinomas
    • Y.C. Lim, S.Y. Oh, Y.Y. Cha, S.H. Kim, X. Jin, and H. Kim Cancer stem cell traits in squamouspheres derived from primary head and neck squamous cell carcinomas Oral Oncol 47 2 2011 83 91
    • (2011) Oral Oncol , vol.47 , Issue.2 , pp. 83-91
    • Lim, Y.C.1    Oh, S.Y.2    Cha, Y.Y.3    Kim, S.H.4    Jin, X.5    Kim, H.6
  • 97
    • 48249105531 scopus 로고    scopus 로고
    • Positive correlations of Oct-4 and nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma
    • S.H. Chiou, C.C. Yu, C.Y. Huang, S.C. Lin, C.J. Liu, and T.H. Tsai Positive correlations of Oct-4 and nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma Clin Cancer Res 14 13 2008 4085 4095
    • (2008) Clin Cancer Res , vol.14 , Issue.13 , pp. 4085-4095
    • Chiou, S.H.1    Yu, C.C.2    Huang, C.Y.3    Lin, S.C.4    Liu, C.J.5    Tsai, T.H.6
  • 99
    • 0031468289 scopus 로고    scopus 로고
    • A novel five-transmembrane hematopoietic stem cell antigen: Isolation, characterization, and molecular cloning
    • S. Miraglia, W. Godfrey, A.H. Yin, K. Atkins, R. Warnke, and J.T. Holden A novel five-transmembrane hematopoietic stem cell antigen: isolation, characterization, and molecular cloning Blood 90 12 1997 5013 5021 (Pubitemid 28007218)
    • (1997) Blood , vol.90 , Issue.12 , pp. 5013-5021
    • Miraglia, S.1    Godfrey, W.2    Yin, A.H.3    Atkins, K.4    Warnke, R.5    Holden, J.T.6    Bray, R.A.7    Waller, E.K.8    Buck, D.W.9
  • 100
    • 0030817282 scopus 로고    scopus 로고
    • Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells
    • DOI 10.1073/pnas.94.23.12425
    • A. Weigmann, D. Corbeil, A. Hellwig, and W.B. Huttner Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells Proc Natl Acad Sci U S A 94 23 1997 12425 12430 (Pubitemid 27492544)
    • (1997) Proceedings of the National Academy of Sciences of the United States of America , vol.94 , Issue.23 , pp. 12425-12430
    • Weigmann, A.1    Corbeil, D.2    Hellwig, A.3    Huttner, W.B.4
  • 109
    • 59049087696 scopus 로고    scopus 로고
    • Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation
    • L.Q. Zhu, P. Gibson, D.S. Currle, Y. Tong, R.J. Richardson, and I.T. Bavazitov Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation Nature 457 2009 603 607
    • (2009) Nature , vol.457 , pp. 603-607
    • Zhu, L.Q.1    Gibson, P.2    Currle, D.S.3    Tong, Y.4    Richardson, R.J.5    Bavazitov, I.T.6
  • 110
    • 76849098162 scopus 로고    scopus 로고
    • A subpopulation of CD133(+) cancer stem-like cells characterized in human oral squamous cell carcinoma confer resistance to chemotherapy
    • Q. Zhang, S. Shi, Y. Yen, T. Brown, J.Q. Ta, and A.D. Le A subpopulation of CD133(+) cancer stem-like cells characterized in human oral squamous cell carcinoma confer resistance to chemotherapy Cancer Lett 289 2 2010 151 160
    • (2010) Cancer Lett , vol.289 , Issue.2 , pp. 151-160
    • Zhang, Q.1    Shi, S.2    Yen, Y.3    Brown, T.4    Ta, J.Q.5    Le, A.D.6
  • 111
    • 33947095683 scopus 로고    scopus 로고
    • CD133, one of the markers of cancer stem cells in Hep-2 cell line
    • DOI 10.1097/01.mlg.0000251586.15299.35, PII 0000553720070300000011
    • L. Zhou, X. Wei, L. Cheng, J. Tian, and J.J. Jiang CD133, one of the markers of cancer stem cells in Hep-2 cell line Laryngoscope 117 3 2007 455 460 (Pubitemid 46407753)
    • (2007) Laryngoscope , vol.117 , Issue.3 , pp. 455-460
    • Zhou, L.1    Wei, X.2    Cheng, L.3    Tian, J.4    Jiang, J.J.5
  • 112
    • 58149508462 scopus 로고    scopus 로고
    • In vivo investigation of CD1323 as a putative marker of cancer stem cells in Hep-2 cell line
    • X.D. Wei, L. Zhou, L. Cheng, J. Tian, J.J. Jiang, and J. Maccallum In vivo investigation of CD1323 as a putative marker of cancer stem cells in Hep-2 cell line Head Neck 31 1 2009 94 101
    • (2009) Head Neck , vol.31 , Issue.1 , pp. 94-101
    • Wei, X.D.1    Zhou, L.2    Cheng, L.3    Tian, J.4    Jiang, J.J.5    MacCallum, J.6
  • 113
    • 67449095320 scopus 로고    scopus 로고
    • Expansion and characterization of cancer stem-like cells in squamous cells carcinoma of the head and neck
    • A. Okamoto, K. Chikamatsu, K. Sakakura, K. Hatsushika, G. Takahashi, and K. Masuyama Expansion and characterization of cancer stem-like cells in squamous cells carcinoma of the head and neck Oral Oncology 45 7 2009 633 639
    • (2009) Oral Oncology , vol.45 , Issue.7 , pp. 633-639
    • Okamoto, A.1    Chikamatsu, K.2    Sakakura, K.3    Hatsushika, K.4    Takahashi, G.5    Masuyama, K.6
  • 114
    • 79960401917 scopus 로고    scopus 로고
    • Bmi-1's maintenance of the proliferative capacity of laryngeal cancer stem cells
    • H. Chen, L. Zhou, T. Dou, G. Wan, H. Tang, and J. Tian Bmi-1's maintenance of the proliferative capacity of laryngeal cancer stem cells Head Neck 33 8 2011 1115 1125
    • (2011) Head Neck , vol.33 , Issue.8 , pp. 1115-1125
    • Chen, H.1    Zhou, L.2    Dou, T.3    Wan, G.4    Tang, H.5    Tian, J.6
  • 115
    • 0025282411 scopus 로고
    • CD44 is the principal cell surface receptor for hyaluronate
    • A. Aruffo, I. Stamenkovic, M. Melnick, C.B. Underhill, and B. Seed CD44 is the principal cell surface receptor for hyaluronate Cell 61 7 1990 1303 1313
    • (1990) Cell , vol.61 , Issue.7 , pp. 1303-1313
    • Aruffo, A.1    Stamenkovic, I.2    Melnick, M.3    Underhill, C.B.4    Seed, B.5
  • 119
    • 0034650486 scopus 로고    scopus 로고
    • Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF and promotes tumor invasion and angiogenesis
    • Q. Yu, and I. Stamenkovic Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis Genes Dev 14 2000 163 176 (Pubitemid 30070982)
    • (2000) Genes and Development , vol.14 , Issue.2 , pp. 163-176
    • Yu, Q.1    Stamenkovic, I.2
  • 121
    • 76249122104 scopus 로고    scopus 로고
    • Characterization of the expression of variant and standard CD44 in prostate cancer cells: Identification of the possible molecular mechanism of CD44/MMP9 complex formation on the cell surface
    • B. Desai, T. Ma, J. Zhu, and M.A. Chellaiah Characterization of the expression of variant and standard CD44 in prostate cancer cells: Identification of the possible molecular mechanism of CD44/MMP9 complex formation on the cell surface J Cell Biochem 108 1 2009 272 284
    • (2009) J Cell Biochem , vol.108 , Issue.1 , pp. 272-284
    • Desai, B.1    Ma, T.2    Zhu, J.3    Chellaiah, M.A.4
  • 122
    • 74649086713 scopus 로고    scopus 로고
    • A basal-cell-like compartment in head and neck squamous cell carcinomas represents the invasive front of the rumor and is expressing MMP-9
    • C.M. Sterz, C. Kulle, B. Dakic, G. Makarova, M.C. Bottcher, and M. Bette A basal-cell-like compartment in head and neck squamous cell carcinomas represents the invasive front of the rumor and is expressing MMP-9 Oral Oncol 46 2 2010 116 122
    • (2010) Oral Oncol , vol.46 , Issue.2 , pp. 116-122
    • Sterz, C.M.1    Kulle, C.2    Dakic, B.3    Makarova, G.4    Bottcher, M.C.5    Bette, M.6
  • 123
    • 78751553162 scopus 로고    scopus 로고
    • Immunoregulatory properties of CD44+ cancer stem-like cells in squamous cell carcinoma of the head and neck
    • K. Chikamatus, G. Takahashi, K. Sakakura, S. Ferrone, and K. Masuyama Immunoregulatory properties of CD44+ cancer stem-like cells in squamous cell carcinoma of the head and neck Head Neck 33 2 2011 208 215
    • (2011) Head Neck , vol.33 , Issue.2 , pp. 208-215
    • Chikamatus, K.1    Takahashi, G.2    Sakakura, K.3    Ferrone, S.4    Masuyama, K.5
  • 124
    • 78649648154 scopus 로고    scopus 로고
    • Cucurbitacin i Suppressed stem-like property and enhanced radiation-induced apoptosis in head and neck squamous carcinoma-derived CD44+ALDH+ cells
    • Y.W. Chen, K.H. Chen, P.I. Huang, Y.C. Chen, G.Y. Chiou, and W.L. Lo Cucurbitacin I Suppressed stem-like property and enhanced radiation-induced apoptosis in head and neck squamous carcinoma-derived CD44+ALDH+ cells Mol Cancer Ther 9 11 2010 2879 2892
    • (2010) Mol Cancer Ther , vol.9 , Issue.11 , pp. 2879-2892
    • Chen, Y.W.1    Chen, K.H.2    Huang, P.I.3    Chen, Y.C.4    Chiou, G.Y.5    Lo, W.L.6
  • 125
    • 54449085703 scopus 로고    scopus 로고
    • CD44s and CD44v6 expression in head and neck epithelia
    • B. Mack, and O. Gires CD44s and CD44v6 expression in head and neck epithelia PLoS One 3 10 2008 e3360
    • (2008) PLoS One , vol.3 , Issue.10 , pp. 3360
    • MacK, B.1    Gires, O.2
  • 127
    • 83555172386 scopus 로고    scopus 로고
    • Frequency of cells expressing CD44, a head and neck cancer stem cell marker: Correlation with tumor aggressiveness
    • Feb14 [Epub ahead of print]
    • Joshua B, Kaplan MJ, Doweck I, Pai R, Weissman IL, Prince ME, et al. Frequency of cells expressing CD44, a head and neck cancer stem cell marker: correlation with tumor aggressiveness. Head Neck 2011;Feb14 [Epub ahead of print].
    • (2011) Head Neck
    • Joshua, B.1    Kaplan, M.J.2    Doweck, I.3    Pai, R.4    Weissman, I.L.5    Prince, M.E.6
  • 128
    • 17744419979 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase gene superfamily: The 2002 update
    • DOI 10.1016/S0009-2797(02)00163-1, PII S0009279702001631
    • N.A. Sophos, and V. Vasiliou Aldehyde dehydrogenase gene superfamily: the 2002 update Chem Biol Interact 143-144 2003 5 22 (Pubitemid 36253575)
    • (2003) Chemico-Biological Interactions , vol.143-144 , pp. 5-22
    • Sophos, N.A.1    Vasiliou, V.2
  • 129
    • 0030024868 scopus 로고    scopus 로고
    • Induction of cyclophosphamide-resistance by aldehyde-dehydrogenase gene transfer
    • M. Magni, S. Shammah, R. Schiro, W. Mellado, R. Dalla-Favera, and A.M. Gianni Induction of cyclophosphamide-resistance by aldehyde-dehydrogenase gene transfer Blood 87 3 1996 1097 1103 (Pubitemid 26043537)
    • (1996) Blood , vol.87 , Issue.3 , pp. 1097-1103
    • Magni, M.1    Shammah, S.2    Schiro, R.3    Mellado, W.4    Dalla-Favera, R.5    Gianni, A.M.6
  • 130
    • 0029685930 scopus 로고    scopus 로고
    • Overexpression of the human aldehyde dehydrogenase class I results in increased resistance to 4-hydroperoxycyclophosphamide
    • J. Moreb, M. Schweder, A. Suresh, and J.R. Zucali Overexpression of the human aldehyde dehydrogenase class 1 results in increased resistance to 4-hydroperoxycyclophosphamide Cancer Gene Ther 3 1 1996 24 30 (Pubitemid 126732422)
    • (1996) Cancer Gene Therapy , vol.3 , Issue.1 , pp. 24-30
    • Moreb, J.1
  • 132
    • 0032955316 scopus 로고    scopus 로고
    • Kinetic properties of the human liver cytosolic aldehyde dehydrogenase for retinal isomers
    • DOI 10.1016/S0006-2952(98)00261-5, PII S0006295298002615
    • P.V. Bhat, and H. Samada Kinetic properties of the human liver cytosolic aldehyde dehydrogenase for retinal isomers Biochem Pharmacol 57 2 1999 195 197 (Pubitemid 29056181)
    • (1999) Biochemical Pharmacology , vol.57 , Issue.2 , pp. 195-197
    • Bhat, P.V.1    Samaha, H.2
  • 133
    • 0025707866 scopus 로고
    • Direct demonstration of elevated aldehyde dehydrogenase in human hematopoietic progenitor cells
    • M.B. Kastan, E. Schlaffer, J.E. Russo, O.M. Colvin, C.I. Civin, and J. Hilton Direct demonstration of elevated aldehyde dehydrogenase in human hematopoietic progenitor cells Blood 75 10 1990 1947 1950
    • (1990) Blood , vol.75 , Issue.10 , pp. 1947-1950
    • Kastan, M.B.1    Schlaffer, E.2    Russo, J.E.3    Colvin, O.M.4    Civin, C.I.5    Hilton, J.6
  • 135
    • 74949129868 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer
    • E. Charafe-Jauffret, C. Ginestier, F. Lovino, C. Tarpin, M. Diebel, and B. Esterni Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer Clin Cancer Res 16 1 2010 45 55
    • (2010) Clin Cancer Res , vol.16 , Issue.1 , pp. 45-55
    • Charafe-Jauffret, E.1    Ginestier, C.2    Lovino, F.3    Tarpin, C.4    Diebel, M.5    Esterni, B.6
  • 136
    • 78649960144 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on Notch signaling
    • J.P. Sullivan, M. Spinola, M. Dodge, M.G. Raso, C. Behrens, and B. Gao Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on Notch signaling Cancer Res 70 23 2010 9937 9948
    • (2010) Cancer Res , vol.70 , Issue.23 , pp. 9937-9948
    • Sullivan, J.P.1    Spinola, M.2    Dodge, M.3    Raso, M.G.4    Behrens, C.5    Gao, B.6
  • 137
    • 67349209852 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1 is a putative marker for cancer stem cells in head and neck squamous cancer
    • Y.C. Chen, Y.W. Chen, H.S. Hsu, L.M. Tseng, P.I. Huang, and K.H. Lu Aldehyde dehydrogenase 1 is a putative marker for cancer stem cells in head and neck squamous cancer Biochem Biophys Res Commun 385 3 2009 307 313
    • (2009) Biochem Biophys Res Commun , vol.385 , Issue.3 , pp. 307-313
    • Chen, Y.C.1    Chen, Y.W.2    Hsu, H.S.3    Tseng, L.M.4    Huang, P.I.5    Lu, K.H.6
  • 138
    • 0029958876 scopus 로고    scopus 로고
    • Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
    • DOI 10.1084/jem.183.4.1797
    • M.A. Goodell, K. Brose, G. Paradis, A.S. Gonner, and R.C. Mulligan Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo J Exp Med 183 4 1996 1797 1806 (Pubitemid 26134320)
    • (1996) Journal of Experimental Medicine , vol.183 , Issue.4 , pp. 1797-1806
    • Goodell, M.A.1    Brose, K.2    Paradis, G.3    Conner, A.S.4    Mulligan, R.C.5
  • 140
    • 33750302541 scopus 로고    scopus 로고
    • SP analysis may be used to identify cancer stem cell populations
    • DOI 10.1016/j.yexcr.2006.08.030, PII S0014482706003636
    • A. Hadnagy, L. Gaboury, R. Beaulieu, and D. Balicki SP analysis may be used to identify cancer stem cell populations Exp Cell Res 312 19 2006 3701 3710 (Pubitemid 44633895)
    • (2006) Experimental Cell Research , vol.312 , Issue.19 , pp. 3701-3710
    • Hadnagy, A.1    Gaboury, L.2    Beaulieu, R.3    Balicki, D.4
  • 141
    • 48349133869 scopus 로고    scopus 로고
    • Side population cells in human cancers
    • C. Wu, and B.A. Alman Side population cells in human cancers Cancer Lett 268 1 2008 1 9
    • (2008) Cancer Lett , vol.268 , Issue.1 , pp. 1-9
    • Wu, C.1    Alman, B.A.2
  • 142
    • 33745505758 scopus 로고    scopus 로고
    • Human side population keratinocytes exhibit long-term proliferative potential and a specific gene expression profile and can form a pluristratified epidermis
    • DOI 10.1634/stemcells.2005-0196
    • G. Larderet, N.O. Fortunel, P. Vaigot, M. Cegalerba, P. Maltere, and O. Zobiri Human side population keratinocytes exhibit long-term proliferative potential and a specific gene expression profile and can form a pluristratified epidermis Stem Cells 24 4 2006 965 974 (Pubitemid 44464729)
    • (2006) Stem Cells , vol.24 , Issue.4 , pp. 965-974
    • Larderet, G.1    Fortunel, N.O.2    Vaigot, P.3    Cegalerba, M.4    Maltere, P.5    Zobiri, O.6    Gidrol, X.7    Waksman, G.8    Martin, M.T.9
  • 143
    • 25444517339 scopus 로고    scopus 로고
    • Identification of novel resident pulmonary stem cells: Form and function of the lung side population
    • DOI 10.1634/stemcells.2005-0039
    • S.M. Majka, M.A. Beutz, M. Hagen, A.A. Izzo, N. Voelkel, and K.M. Helm Identification of novel resident pulmonary stem cells: form and function of the lung side population Stem cells 23 8 2005 1073 1081 (Pubitemid 41377723)
    • (2005) Stem Cells , vol.23 , Issue.8 , pp. 1073-1081
    • Majka, S.M.1    Beurz, M.A.2    Hagen, M.3    Izzo, A.A.4    Voelkel, N.5    Helm, K.M.6
  • 144
    • 0344011434 scopus 로고    scopus 로고
    • Distinct Populations of Forebrain Neural Stem and Progenitor Cells Can Be Isolated Using Side-Population Analysis
    • M. Kim, and C.M. Morshead Distinct populations of forebrain neural stem and progenitor cells can be isolated using side-population analysis J Neurosci 23 33 2003 10703 10709 (Pubitemid 37485284)
    • (2003) Journal of Neuroscience , vol.23 , Issue.33 , pp. 10703-10709
    • Kim, M.1    Morshead, C.M.2
  • 146
    • 33745924696 scopus 로고    scopus 로고
    • Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties
    • DOI 10.1002/hep.21227
    • T. Chiba, K. Kita, Y.W. Zheng, O. Yokosuka, H. Saisho, and A. Iwama Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties Hepatology 44 1 2006 240 251 (Pubitemid 44049156)
    • (2006) Hepatology , vol.44 , Issue.1 , pp. 240-251
    • Chiba, T.1    Kita, K.2    Zheng, Y.-W.3    Yokosuka, O.4    Saisho, H.5    Iwama, A.6    Nakauchi, H.7    Taniguchi, H.8
  • 148
    • 33744985294 scopus 로고    scopus 로고
    • Characterization of a side population of cancer cells from human gastrointestinal system
    • DOI 10.1634/stemcells.2005-0282
    • N. Hareguichi, T. Utsunomiya, H. Inoue, F. Tanaka, K. Mimori, and G.F. Barnard Characterization of a side population of cancer cells from human gastrointestinal system Stem Cells 24 3 2006 506 513 (Pubitemid 44464754)
    • (2006) Stem Cells , vol.24 , Issue.3 , pp. 506-513
    • Haraguchi, N.1    Utsunomiya, T.2    Inoue, H.3    Tanaka, F.4    Mimori, K.5    Barnard, G.F.6    Mori, M.7
  • 151
    • 34248529666 scopus 로고    scopus 로고
    • Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line
    • DOI 10.1158/0008-5472.CAN-06-4343
    • J. Wang, L.P. Guo, L.Z. Chen, Y.X. Zeng, and S.H. Lu Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line Cancer Res 67 8 2007 3716 3724 (Pubitemid 46762157)
    • (2007) Cancer Research , vol.67 , Issue.8 , pp. 3716-3724
    • Wang, J.1    Guo, L.-P.2    Chen, L.-Z.3    Zeng, Y.-X.4    Shih, H.L.5
  • 152
    • 62949157910 scopus 로고    scopus 로고
    • Side population in oral squamous cell carcinoma possesses tumor stem cell phenotypes
    • P. Zhang, Y. Zhang, L. Mao, Z. Zhang, and W. Chen Side population in oral squamous cell carcinoma possesses tumor stem cell phenotypes Cancer Lett 277 2 2009 227 234
    • (2009) Cancer Lett , vol.277 , Issue.2 , pp. 227-234
    • Zhang, P.1    Zhang, Y.2    Mao, L.3    Zhang, Z.4    Chen, W.5
  • 153
    • 77955372945 scopus 로고    scopus 로고
    • Characterization of side populations in HNSCC: Highly invasive, chemoresistant and abnormal Wnt signaling
    • J. Song, I. Chang, Z. Chen, M. Kang, and C.Y. Wang Characterization of side populations in HNSCC: highly invasive, chemoresistant and abnormal Wnt signaling PLoS One 5 7 2010 e11456
    • (2010) PLoS One , vol.5 , Issue.7 , pp. 11456
    • Song, J.1    Chang, I.2    Chen, Z.3    Kang, M.4    Wang, C.Y.5
  • 154
    • 78649476631 scopus 로고    scopus 로고
    • Characterization of side population cells from laryngeal cancer cell lines
    • G.L. Wan, L. Zhou, M. Xie, H. Chen, and J. Tian Characterization of side population cells from laryngeal cancer cell lines Head Neck 32 10 2010 1302 1309
    • (2010) Head Neck , vol.32 , Issue.10 , pp. 1302-1309
    • Wan, G.L.1    Zhou, L.2    Xie, M.3    Chen, H.4    Tian, J.5
  • 156
    • 3242754448 scopus 로고    scopus 로고
    • Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity
    • DOI 10.1038/ni1080
    • K.J. Hope, L. Jin, and J.E. Dick Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity Nat Immumol 5 2004 738 743 (Pubitemid 39023306)
    • (2004) Nature Immunology , vol.5 , Issue.7 , pp. 738-743
    • Hope, K.J.1    Jin, L.2    Dick, J.E.3
  • 157
    • 34547113747 scopus 로고    scopus 로고
    • Tumor growth need not be driven by rare cancer stem cells
    • DOI 10.1126/science.1142596
    • P.N. Kelly, A. Dakic, J.M. Adams, S.L. Nutt, and A. Strasser Tumor growth need not be driven by rare cancer stem cells Science 317 2007 337 (Pubitemid 47106366)
    • (2007) Science , vol.317 , Issue.5836 , pp. 337
    • Kelly, P.N.1    Dakic, A.2    Adams, J.M.3    Nutt, S.L.4    Strasser, A.5
  • 159
    • 78049339202 scopus 로고    scopus 로고
    • Tumor-initiating activity and tumor morphology of HNSCC is modulated by interactions between clonal variants within the tumor
    • S.R. Cameron, A.L. Dahler, L.B. Endo-Munoz, I. Jabbar, G.P. Thomas, and P.J. Leo Tumor-initiating activity and tumor morphology of HNSCC is modulated by interactions between clonal variants within the tumor Lab Invest 90 11 2010 1594 1603
    • (2010) Lab Invest , vol.90 , Issue.11 , pp. 1594-1603
    • Cameron, S.R.1    Dahler, A.L.2    Endo-Munoz, L.B.3    Jabbar, I.4    Thomas, G.P.5    Leo, P.J.6
  • 160
    • 84855863112 scopus 로고    scopus 로고
    • Endothelial derived factors inhibit anoikis of head and neck cancer stem cells
    • doi:10.1016/j.oraloncology.2011.09.010 Oct 17. [Epub ahead of print]
    • Campos M, Neiva K, Meyers K, Krishnamurthy S, Nör JE. Endothelial derived factors inhibit anoikis of head and neck cancer stem cells. Oral Oncol 2011 Oct 17. [Epub ahead of print]. doi:10.1016/j.oraloncology.2011.09.010.
    • (2011) Oral Oncol
    • Campos, M.1    Neiva, K.2    Meyers, K.3    Krishnamurthy, S.4    Nör, J.E.5


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