-
2
-
-
84874249393
-
The immune system's involvement in obesity-driven Type 2 diabetes
-
Shu CJ, Benoist C, Mathis D. The immune system's involvement in obesity-driven Type 2 diabetes. Semin. Immunol. 24(6), 436-442 (2013).
-
(2013)
Semin. Immunol
, vol.24
, Issue.6
, pp. 436-442
-
-
Shu, C.J.1
Benoist, C.2
Mathis, D.3
-
3
-
-
84874247282
-
Implication of inflammatory signaling pathways in obesity-induced insulin resistance
-
Tanti JF, Ceppo F, Jager J, Berthou F. Implication of inflammatory signaling pathways in obesity-induced insulin resistance. Front. Endocrinol. (Lausanne) 3, 181 (2012).
-
(2012)
Front. Endocrinol. (Lausanne)
, vol.3
, pp. 181
-
-
Tanti, J.F.1
Ceppo, F.2
Jager, J.3
Berthou, F.4
-
4
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
DOI 10.1172/JCI200319246
-
Weisberg SP, Mccann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J. Clin. Invest. 112(12), 1796-1808 (2003). (Pubitemid 38063703)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante Jr., A.W.6
-
5
-
-
84860441011
-
Inflammation and lipid signaling in the etiology of insulin resistance
-
Glass CK, Olefsky JM. Inflammation and lipid signaling in the etiology of insulin resistance. Cell Metab. 15(5), 635-645 (2012).
-
(2012)
Cell Metab
, vol.15
, Issue.5
, pp. 635-645
-
-
Glass, C.K.1
Olefsky, J.M.2
-
6
-
-
44449118921
-
Fatty acid-binding proteins: Role in metabolic diseases and potential as drug targets
-
DOI 10.1038/nrd2589, PII NRD2589
-
Furuhashi M, Hotamisligil GS. Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets. Nat. Rev. Drug Discov. 7(6), 489-503 (2008). (Pubitemid 351767117)
-
(2008)
Nature Reviews Drug Discovery
, vol.7
, Issue.6
, pp. 489-503
-
-
Furuhashi, M.1
Hotamisligil, G.S.2
-
7
-
-
4444296764
-
Fatty acid binding proteins - The evolutionary crossroads of inflammatory and metabolic responses
-
Makowski L, Hotamisligil GS. Fatty acid binding proteins-the evolutionary crossroads of inflammatory and metabolic responses. J. Nutr. 134(9), 2464S-2468S (2004). (Pubitemid 39201622)
-
(2004)
Journal of Nutrition
, vol.134
, Issue.9
-
-
Makowski, L.1
Hotamisligil, G.S.2
-
8
-
-
77955703092
-
RAGE: A multi-ligand receptor unveiling novel insights in health and disease
-
Alexiou P, Chatzopoulou M, Pegklidou K, Demopoulos VJ. RAGE: a multi-ligand receptor unveiling novel insights in health and disease. Curr. Med. Chem. 17(21), 2232-2252 (2010).
-
(2010)
Curr. Med. Chem
, vol.17
, Issue.21
, pp. 2232-2252
-
-
Alexiou, P.1
Chatzopoulou, M.2
Pegklidou, K.3
Demopoulos, V.J.4
-
9
-
-
64749107607
-
RAGE (receptor for advanced glycation endproducts), RAGE ligands, and their role in cancer and inflammation
-
Sparvero LJ, Asafu-Adjei D, Kang R et al. RAGE (receptor for advanced glycation endproducts), RAGE ligands, and their role in cancer and inflammation. J. Transl. Med. 7(17), 17 (2009).
-
(2009)
J. Transl. Med
, vol.7
, Issue.17
, pp. 17
-
-
Sparvero, L.J.1
Asafu-Adjei, D.2
Kang, R.3
-
10
-
-
79959810354
-
AGE-RAGE interaction and oxidative stress in obesity-related renal dysfunction
-
Tomino Y, Hagiwara S, Gohda T. AGE-RAGE interaction and oxidative stress in obesity-related renal dysfunction. Kidney Int. 80(2), 133-135 (2011).
-
(2011)
Kidney Int
, vol.80
, Issue.2
, pp. 133-135
-
-
Tomino, Y.1
Hagiwara, S.2
Gohda, T.3
-
11
-
-
34250904186
-
Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2
-
DOI 10.1038/nature05844, PII NATURE05844
-
Furuhashi M, Tuncman G, Görgün C et al. Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2. Nature 447(7147), 959-965 (2007). (Pubitemid 46975747)
-
(2007)
Nature
, vol.447
, Issue.7147
, pp. 959-965
-
-
Furuhashi, M.1
Tuncman, G.2
Gorgun, C.Z.3
Makowski, L.4
Atsumi, G.5
Vaillancourt, E.6
Kono, K.7
Babaev, V.R.8
Fazio, S.9
Linton, M.F.10
Sulsky, R.11
Robl, J.A.12
Parker, R.A.13
Hotamisligil, G.S.14
-
13
-
-
35448954376
-
Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression
-
DOI 10.1158/0008-5472.CAN-07-2354
-
Bunt SK, Yang L, Sinha P, Clements VK, Leips J, Ostrand-Rosenberg S. Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression. Cancer Res. 67(20), 10019-10026 (2007). (Pubitemid 47621253)
-
(2007)
Cancer Research
, vol.67
, Issue.20
, pp. 10019-10026
-
-
Bunt, S.K.1
Yang, L.2
Sinha, P.3
Clements, V.K.4
Leips, J.5
Ostrand-Rosenberg, S.6
-
14
-
-
74849087406
-
Adipocyte fatty acid-binding protein as a novel prognostic factor in obese breast cancer patients
-
Hancke K, Grubeck D, Hauser N, Kreienberg R, Weiss JM. Adipocyte fatty acid-binding protein as a novel prognostic factor in obese breast cancer patients. Breast Cancer Res. Treat 119(2), 367-377 (2010).
-
(2010)
Breast Cancer Res. Treat
, vol.119
, Issue.2
, pp. 367-377
-
-
Hancke, K.1
Grubeck, D.2
Hauser, N.3
Kreienberg, R.4
Weiss, J.M.5
-
15
-
-
81255157465
-
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor
-
Nieman K, Kenny H, Penicka C et al. Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Nat. Med. 17(11), 1498-1503 (2011).
-
(2011)
Growth. Nat. Med
, vol.17
, Issue.11
, pp. 1498-1503
-
-
Nieman, K.1
Kenny, H.2
Penicka, C.3
-
16
-
-
77955769241
-
The receptor RAGE: Bridging inflammation and cancer
-
Riehl A, Nemeth J, Angel P, Hess J. The receptor RAGE: bridging inflammation and cancer. Cell Commun. Signal. 7, 12 (2009).
-
(2009)
Cell Commun. Signal
, vol.7
, pp. 12
-
-
Riehl, A.1
Nemeth, J.2
Angel, P.3
Hess, J.4
-
17
-
-
54549089856
-
Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice
-
Tu S, Bhagat G, Cui G et al. Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. Cancer Cell 14(5), 408-419 (2008).
-
(2008)
Cancer Cell
, vol.14
, Issue.5
, pp. 408-419
-
-
Tu, S.1
Bhagat, G.2
Cui, G.3
-
18
-
-
0037418208
-
IL-1 is required for tumor invasiveness and angiogenesis
-
DOI 10.1073/pnas.0437939100
-
Voronov E, Shouval DS, Krelin Y et al. IL-1 is required for tumor invasiveness and angiogenesis. Proc. Natl Acad. Sci. USA 100(5), 2645-2650 (2003). (Pubitemid 36297552)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.5
, pp. 2645-2650
-
-
Voronov, E.1
Shouval, D.S.2
Krelin, Y.3
Cagnano, E.4
Benharroch, D.5
Iwakura, Y.6
Dinarello, C.A.7
Apte, R.N.8
-
19
-
-
0022530255
-
Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones
-
Besedovsky H, Del Rey A, Sorkin E, Dinarello CA. Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones. Science 233(4764), 652-654 (1986). (Pubitemid 16011614)
-
(1986)
Science
, vol.233
, Issue.4764
, pp. 652-654
-
-
Besedovsky, H.1
Del Rey, A.2
Sorkin, E.3
Dinarello, C.A.4
-
20
-
-
84861329882
-
Interleukin-1 (IL-1) family of cytokines: Role in Type 2 diabetes
-
Banerjee M, Saxena M. Interleukin-1 (IL-1) family of cytokines: role in Type 2 diabetes. Clinical Chim. Acta 413(15-16), 1163-1170 (2012).
-
(2012)
Clinical Chim. Acta
, vol.413
, Issue.15-16
, pp. 1163-1170
-
-
Banerjee, M.1
Saxena, M.2
-
21
-
-
79952102031
-
Inflammasome activation and IL-1b and IL-18 processing during infection
-
van de Veerdonk FL, Netea MG, Dinarello CA, Joosten LA. Inflammasome activation and IL-1b and IL-18 processing during infection. Trends Immunol. 32(3), 110-116 (2011).
-
(2011)
Trends Immunol
, vol.32
, Issue.3
, pp. 110-116
-
-
Van De Veerdonk, F.L.1
Netea, M.G.2
Dinarello, C.A.3
Joosten, L.A.4
-
22
-
-
0033163393
-
Is NF-kappaB the sensor of oxidative stress?
-
Li N, Karin M. Is NF-kappaB the sensor of oxidative stress? FASEB J. 13(10), 1137-1143 (2012).
-
(2012)
FASEB J
, vol.13
, Issue.10
, pp. 1137-1143
-
-
Li, N.1
Karin, M.2
-
23
-
-
84864545087
-
Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
-
Dinarello CA, Simon A, Van Der Meer JW. Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases. Nat. Rev. Drug Discov. 11(8), 633-652 (2012).
-
(2012)
Nat. Rev. Drug Discov
, vol.11
, Issue.8
, pp. 633-652
-
-
Dinarello, C.A.1
Simon, A.2
Van Der Meer, J.W.3
-
24
-
-
1642285783
-
NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
DOI 10.1016/S1074-7613(04)00046-9, PII S1074761304000469
-
Agostini L, Martinon F, Burns K, Mcdermott MF, Hawkins PN, Tschopp J. NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 20(3), 319-325 (2004). (Pubitemid 38388233)
-
(2004)
Immunity
, vol.20
, Issue.3
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
26
-
-
84860225411
-
Interleukin-1 assembles a proangiogenic signaling module consisting of caveolin-1, tumor necrosis factor receptor-associated factor 6, p38-mitogen-activated protein kinase (MAPK), and MAPK-activated protein kinase 2 in endothelial cells
-
Jagielska J, Kapopara P, Salguero G et al. Interleukin-1 assembles a proangiogenic signaling module consisting of caveolin-1, tumor necrosis factor receptor-associated factor 6, p38-mitogen-activated protein kinase (MAPK), and MAPK-activated protein kinase 2 in endothelial cells. Atheroscler. Thromb. Vasc. Biol. 32(5), 1280-1288 (2012).
-
(2012)
Atheroscler. Thromb. Vasc. Biol
, vol.32
, Issue.5
, pp. 1280-1288
-
-
Jagielska, J.1
Kapopara, P.2
Salguero, G.3
-
27
-
-
0141784866
-
IL-1 plays an important role in lipid metabolism by regulating insulin levels under physiological conditions
-
DOI 10.1084/jem.20030299
-
Matsuki T, Horai R, Sudo K, Iwakura Y. IL-1 plays an important role in lipid metabolism by regulating insulin levels under physiological conditions. J. Exp. Med. 198(6), 877-888 (2003). (Pubitemid 37152925)
-
(2003)
Journal of Experimental Medicine
, vol.198
, Issue.6
, pp. 877-888
-
-
Matsuki, T.1
Horai, R.2
Sudo, K.3
Iwakura, Y.4
-
28
-
-
84862736086
-
Interleukin-1 beta: A potential link between stress and the development of visceral obesity
-
Speaker K, Fleshner M. Interleukin-1 beta: a potential link between stress and the development of visceral obesity. BMC Physiol. 12:8 (2012).
-
(2012)
BMC Physiol
, vol.12
, Issue.8
-
-
Speaker, K.1
Fleshner, M.2
-
29
-
-
79955148909
-
A clinical perspective of IL-1beta as the gatekeeper of inflammation
-
Dinarello CA. A clinical perspective of IL-1beta as the gatekeeper of inflammation. Eur. J. Immunol. 41(5), 1203-1217 (2011).
-
(2011)
Eur. J. Immunol
, vol.41
, Issue.5
, pp. 1203-1217
-
-
Dinarello, C.A.1
-
30
-
-
79953813107
-
Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
-
Dinarello C. Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. Blood 117(14) 3720-3732 (2011).
-
(2011)
Blood
, vol.117
, Issue.14
, pp. 3720-3732
-
-
Dinarello, C.1
-
31
-
-
79955615961
-
Interleukin-targeted therapy for metabolic syndrome and type 2 diabetes
-
Maedler K, Dharmadhikari G, Schumann D, Størling J. Interleukin-targeted therapy for metabolic syndrome and type 2 diabetes. Handb. Exp. Pharmacol. 203, 257-278 (2011).
-
(2011)
Handb. Exp. Pharmacol
, vol.203
, pp. 257-278
-
-
Maedler, K.1
Dharmadhikari, G.2
Schumann, D.3
Størling, J.4
-
32
-
-
77952298772
-
HMGB1 and RAGE in inflammation and cancer
-
Sims GP, Rowe DC, Rietdijk ST, Herbst R, Coyle AJ. HMGB1 and RAGE in inflammation and cancer. Annu. Rev. Immunol. 28, 367-388 (2010).
-
(2010)
Annu. Rev. Immunol
, vol.28
, pp. 367-388
-
-
Sims, G.P.1
Rowe, D.C.2
Rietdijk, S.T.3
Herbst, R.4
Coyle, A.J.5
-
33
-
-
0026650438
-
Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface
-
Schmidt AM, Vianna M, Gerlach M et al. Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface. J. Biol. Chem. 267(21), 14987-14997 (1992).
-
(1992)
J. Biol. Chem
, vol.267
, Issue.21
, pp. 14987-14997
-
-
Schmidt, A.M.1
Vianna, M.2
Gerlach, M.3
-
34
-
-
84863416913
-
Receptor for advanced glycation end products (RAGE) partially mediates HMGB1-ERKs activation in clear cell renal cell carcinoma
-
Lin L, Zhong K, Sun Z, Wu G, Ding G. Receptor for advanced glycation end products (RAGE) partially mediates HMGB1-ERKs activation in clear cell renal cell carcinoma. J. Cancer Res. Clin. Oncol. 138(1), 1-22 (2012).
-
(2012)
J. Cancer Res. Clin. Oncol
, vol.138
, Issue.1
, pp. 1-22
-
-
Lin, L.1
Zhong, K.2
Sun, Z.3
Wu, G.4
Ding, G.5
-
35
-
-
79959567198
-
Alternative splicing of RAGE: Roles in biology and disease
-
Kalea AZ, Schmidt AM, Hudson BI. Alternative splicing of RAGE: roles in biology and disease. Front. Biosci. 16, 2756-2770 (2011).
-
(2011)
Front. Biosci
, vol.16
, pp. 2756-2770
-
-
Kalea, A.Z.1
Schmidt, A.M.2
Hudson, B.I.3
-
36
-
-
77950898092
-
Fueling inflammation at tumor microenvironment: The role of multiligand/RAGE axis
-
Rojas A, Figueroa H, Morales E. Fueling inflammation at tumor microenvironment: the role of multiligand/RAGE axis. Carcinogenesis 31(3), 334-341 (2010).
-
(2010)
Carcinogenesis
, vol.31
, Issue.3
, pp. 334-341
-
-
Rojas, A.1
Figueroa, H.2
Morales, E.3
-
37
-
-
27744453362
-
Understanding RAGE, the receptor for advanced glycation end products
-
DOI 10.1007/s00109-005-0688-7
-
Bierhaus A, Humpert PM, Morcos M et al. Understanding RAGE, the receptor for advanced glycation end products. J. Mol. Med. (Berl.) 83(11), 876-886 (2005). (Pubitemid 41598688)
-
(2005)
Journal of Molecular Medicine
, vol.83
, Issue.11
, pp. 876-886
-
-
Bierhaus, A.1
Humpert, P.M.2
Morcos, M.3
Wendt, T.4
Chavakis, T.5
Arnold, B.6
Stern, D.M.7
Nawroth, P.P.8
-
38
-
-
54049108485
-
A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)
-
Raucci A, Cugusi S, Antonelli A et al. A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10). FASEB J. 22(10), 3716-3727 (2008).
-
(2008)
FASEB J
, vol.22
, Issue.10
, pp. 3716-3727
-
-
Raucci, A.1
Cugusi, S.2
Antonelli, A.3
-
39
-
-
34249779532
-
Nuclear heat shock protein 72 as a negative regulator of oxidative stress (hydrogen peroxide)-induced HMGB1 cytoplasmic translocation and release
-
Tang D, Kang R, Xiao W et al. Nuclear heat shock protein 72 as a negative regulator of oxidative stress (hydrogen peroxide)-induced HMGB1 cytoplasmic translocation and release. J. Immunol. 178(11), 7376-7384 (2007). (Pubitemid 46847465)
-
(2007)
Journal of Immunology
, vol.178
, Issue.11
, pp. 7376-7384
-
-
Tang, D.1
Kang, R.2
Xiao, W.3
Jiang, L.4
Liu, M.5
Shi, Y.6
Wang, K.7
Wang, H.8
Xiao, X.9
-
40
-
-
34247236200
-
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
-
DOI 10.1038/ni1457, PII NI1457
-
Tian J, Avalos AM, Mao SY et al. Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. Nat. Immunol. 8(5), 487-496 (2007). (Pubitemid 46605917)
-
(2007)
Nature Immunology
, vol.8
, Issue.5
, pp. 487-496
-
-
Tian, J.1
Avalos, A.M.2
Mao, S.-Y.3
Chen, B.4
Senthil, K.5
Wu, H.6
Parroche, P.7
Drabic, S.8
Golenbock, D.9
Sirois, C.10
Hua, J.11
An, L.L.12
Audoly, L.13
La Rosa, G.14
Bierhaus, A.15
Naworth, P.16
Marshak-Rothstein, A.17
Crow, M.K.18
Fitzgerald, K.A.19
Latz, E.20
Kiener, P.A.21
Coyle, A.J.22
more..
-
41
-
-
45149116659
-
Androgen deprivation therapy in prostate cancer and metabolic risk for atherosclerosis
-
DOI 10.1210/jc.2007-2595
-
Shahani S, Braga-Basaria M, Basaria S. Androgen deprivation therapy in prostate cancer and metabolic risk for atherosclerosis. J. Clin. Endocrinol. Metab. 93(6), 2042-2049 (2008). (Pubitemid 351831513)
-
(2008)
Journal of Clinical Endocrinology and Metabolism
, vol.93
, Issue.6
, pp. 2042-2049
-
-
Shahani, S.1
Braga-Basaria, M.2
Basaria, S.3
-
42
-
-
59649126956
-
Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: Implications for the pathogenesis of SLE
-
Urbonaviciute V, Furnrohr BG, Meister S et al. Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE. J. Exp. Med. 205(13), 3007-3018 (2008).
-
(2008)
J. Exp. Med
, vol.205
, Issue.13
, pp. 3007-3018
-
-
Urbonaviciute, V.1
Furnrohr, B.G.2
Meister, S.3
-
43
-
-
53049088890
-
Tumors sound the alarmin(s)
-
Coffelt SB, Scandurro AB. Tumors sound the alarmin(s). Cancer Res. 68(16), 6482-6485 (2008).
-
(2008)
Cancer Res
, vol.68
, Issue.16
, pp. 6482-6485
-
-
Coffelt, S.B.1
Scandurro, A.B.2
-
44
-
-
20944436774
-
The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism
-
DOI 10.1172/JCI200522782
-
Abeyama K, Stern DM, Ito Y et al. The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism. J. Clin. Invest. 115(5), 1267-1274 (2005). (Pubitemid 40629045)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.5
, pp. 1267-1274
-
-
Abeyama, K.1
Stern, D.M.2
Ito, Y.3
Kawahara, K.-I.4
Yoshimoto, Y.5
Tanaka, M.6
Uchimura, T.7
Ida, N.8
Yamazaki, Y.9
Yamada, S.10
Yamamoto, Y.11
Yamamoto, H.12
Iino, S.13
Taniguchi, N.14
Maruyama, I.15
-
45
-
-
79952751056
-
Septic shock is associated with receptor for advanced glycation end products ligation of LPS
-
Yamamoto Y, Harashima A, Saito H et al. Septic shock is associated with receptor for advanced glycation end products ligation of LPS. J. Immunol. 186(5), 3248-3257 (2011).
-
(2011)
J. Immunol
, vol.186
, Issue.5
, pp. 3248-3257
-
-
Yamamoto, Y.1
Harashima, A.2
Saito, H.3
-
46
-
-
13644264763
-
RAGE limits regeneration after massive liver injury by coordinated suppression of TNF-α and NF-κB
-
DOI 10.1084/jem.20040934
-
Cataldegirmen G, Zeng S, Feirt N et al. RAGE limits regeneration after massive liver injury by coordinated suppression of TNF-alpha and NF-kappaB. J. Exp. Med. 201(3), 473-484 (2005). (Pubitemid 40229421)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.3
, pp. 473-484
-
-
Cataldegirmen, G.1
Zeng, S.2
Feirt, N.3
Ippagunta, N.4
Dun, H.5
Qu, W.6
Lu, Y.7
Ling, L.R.8
Hofmann, M.A.9
Kislinger, T.10
Pachydaki, S.I.11
Jenkins, D.G.12
Weinberg, A.13
Lefkowitch, J.14
Rogiers, X.15
Shi, F.Y.16
Schmidt, A.M.17
Emond, J.C.18
-
47
-
-
33645514606
-
Receptor for advanced-glycation end products: Key modulator of myocardial ischemic injury
-
Bucciarelli LG, Kaneko M, Ananthakrishnan R et al. Receptor for advanced-glycation end products: key modulator of myocardial ischemic injury. Circulation 113(9), 1226-1234 (2006).
-
(2006)
Circulation
, vol.113
, Issue.9
, pp. 1226-1234
-
-
Bucciarelli, L.G.1
Kaneko, M.2
Ananthakrishnan, R.3
-
48
-
-
84255163024
-
Receptor for AGE (RAGE): Signaling mechanisms in the pathogenesis of diabetes and its complications
-
Ramasamy R, Yan S, Schmidt A. Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications. Ann. NY Acad. Sci. 1243, 88-102 (2011).
-
(2011)
Ann. NY Acad. Sci
, vol.1243
, pp. 88-102
-
-
Ramasamy, R.1
Yan, S.2
Schmidt, A.3
-
49
-
-
12144287484
-
Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family
-
DOI 10.1073/pnas.0308680101
-
Garlanda C, Riva F, Polentarutti N et al. Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family. Proc. Natl Acad. Sci. USA 101(10), 3522-3526 (2004). (Pubitemid 38338228)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.10
, pp. 3522-3526
-
-
Garlanda, C.1
Riva, F.2
Polentarutti, N.3
Buracchi, C.4
Sironi, M.5
De Bortoli, M.6
Muzio, M.7
Bergottini, R.8
Scanziani, E.9
Vecchi, A.10
Hirsch, E.11
Mantovani, A.12
-
50
-
-
34250160687
-
RAGE on the toll road? cell mol
-
Lin L. RAGE on the Toll Road? Cell Mol. Immunol. 3(5), 351-358 (2006).
-
(2006)
Immunol
, vol.3
, Issue.5
, pp. 351-358
-
-
Lin, L.1
-
51
-
-
53349125963
-
Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells
-
Sinha P, Okoro C, Foell D, Freeze HH, Ostrand-Rosenberg S, Srikrishna G. Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells. J. Immunol. 181(7), 4666-4675 (2008).
-
(2008)
J. Immunol
, vol.181
, Issue.7
, pp. 4666-4675
-
-
Sinha, P.1
Okoro, C.2
Foell, D.3
Freeze, H.H.4
Ostrand-Rosenberg, S.5
Srikrishna, G.6
-
52
-
-
84874383315
-
Inflammation in the pathogenesis of microvascular complications in diabetes
-
Nguyen DV, Shaw LC, Grant MB. Inflammation in the pathogenesis of microvascular complications in diabetes. Front. Endocrinol. (Lausanne) 3, 170 (2012).
-
(2012)
Front. Endocrinol. (Lausanne)
, vol.3
, pp. 170
-
-
Nguyen, D.V.1
Shaw, L.C.2
Grant, M.B.3
-
53
-
-
84873879390
-
Hypoxia-mediated regulation of macrophage functions in pathophysiology
-
Riboldi E, Porta C, Morlacchi S, Viola A, Mantovani A, Sica A. Hypoxia-mediated regulation of macrophage functions in pathophysiology. Int. Immunol. 25(2), 67-75 (2012).
-
(2012)
Int. Immunol
, vol.25
, Issue.2
, pp. 67-75
-
-
Riboldi, E.1
Porta, C.2
Morlacchi, S.3
Viola, A.4
Mantovani, A.5
Sica, A.6
-
54
-
-
84856739946
-
Hypoxia-inducible factors in physiology and medicine
-
Semenza GL. Hypoxia-inducible factors in physiology and medicine. Cell 148(3), 399-408 (2012).
-
(2012)
Cell
, vol.148
, Issue.3
, pp. 399-408
-
-
Semenza, G.L.1
-
55
-
-
84862566201
-
A microarray analysis of the hypoxia-induced modulation of gene expression in human adipocytes
-
Mazzatti D, Lim FL, O'Hara A, Wood IS, Trayhurn P. A microarray analysis of the hypoxia-induced modulation of gene expression in human adipocytes. Arch. Physiol. Biochem. 118(3), 112-120 (2012).
-
(2012)
Arch. Physiol. Biochem
, vol.118
, Issue.3
, pp. 112-120
-
-
Mazzatti, D.1
Lim, F.L.2
O'Hara, A.3
Wood, I.S.4
Trayhurn, P.5
-
56
-
-
84655174598
-
Fatty acids alleviate adipose tissue inflammation and insulin resistance: Mechanistic insights
-
Kalupahana NS, Claycombe KJ, Moustaid-Moussa N. (n-3) fatty acids alleviate adipose tissue inflammation and insulin resistance: mechanistic insights. Adv. Nutr. 2(4), 304-316 (2011).
-
(2011)
Adv. Nutr
, vol.2
, Issue.4
, pp. 304-316
-
-
Kalupahana, N.S.1
Claycombe, K.J.2
Moustaid-Moussa, N.3
-
57
-
-
80054903245
-
Elimination of the NLRP3-ASC inflammasome protects against chronic obesity-induced pancreatic damage
-
Youm Y, Adijiang A, Vandanmagsar B, Burk D, Ravussin A, Dixit V. Elimination of the NLRP3-ASC inflammasome protects against chronic obesity-induced pancreatic damage. Endocrinology 152(11), 4039-4045 (2011).
-
(2011)
Endocrinology
, vol.152
, Issue.11
, pp. 4039-4045
-
-
Youm, Y.1
Adijiang, A.2
Vandanmagsar, B.3
Burk, D.4
Ravussin, A.5
Dixit, V.6
-
58
-
-
0037279517
-
The hypoxic tumour microenvironment and metastatic progression
-
DOI 10.1023/A:1022939318102
-
Subarsky P, Hill RP. The hypoxic tumour microenvironment and metastatic progression. Clin. Exp. Metastasis 20(3), 237-250 (2003). (Pubitemid 36513228)
-
(2003)
Clinical and Experimental Metastasis
, vol.20
, Issue.3
, pp. 237-250
-
-
Subarsky, P.1
Hill, R.P.2
-
59
-
-
84861536618
-
High-mobility group box 1 activates caspase-1 and promotes hepatocellular carcinoma invasiveness and metastases
-
Yan W, Chang Y, Liang X et al. High-mobility group box 1 activates caspase-1 and promotes hepatocellular carcinoma invasiveness and metastases. Hepatology 55(6), 1863-1875 (2012).
-
(2012)
Hepatology
, vol.55
, Issue.6
, pp. 1863-1875
-
-
Yan, W.1
Chang, Y.2
Liang, X.3
-
60
-
-
84879792938
-
Current therapeutic interventions in the glycation pathway: Evidence from clinical studies
-
doi:10.1111/dom.12058 Epub ahead of print
-
Engelen L, Stehouwer CD, Schalkwijk CG. Current therapeutic interventions in the glycation pathway: evidence from clinical studies. Diabetes Obes. Metab. doi:10.1111/dom.12058 (2012) (Epub ahead of print).
-
(2012)
Diabetes Obes. Metab
-
-
Engelen, L.1
Stehouwer, C.D.2
Schalkwijk, C.G.3
-
61
-
-
26444478269
-
Advanced glycation end products and RAGE: A common thread in aging, diabetes, neurodegeneration, and inflammation
-
DOI 10.1093/glycob/cwi053
-
Ramasamy R, Vannucci SJ, Yan SS, Herold K, Yan SF, Schmidt AM. Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation. Glycobiology 15(7), 16R-28R (2005). (Pubitemid 41417992)
-
(2005)
Glycobiology
, vol.15
, Issue.7
-
-
Ramasamy, R.1
Vannucci, S.J.2
Yan, S.S.D.3
Herold, K.4
Yan, S.F.5
Schmidt, A.M.6
-
62
-
-
84866470030
-
Advanced glycation end product cross-link breaker attenuates diabetes-induced cardiac dysfunction by improving sarcoplasmic reticulum calcium handling
-
Kranstuber AL, Del Rio C, Biesiadecki BJ et al. Advanced glycation end product cross-link breaker attenuates diabetes-induced cardiac dysfunction by improving sarcoplasmic reticulum calcium handling. Front. Physiol. 3, 292 (2012).
-
(2012)
Front. Physiol
, vol.3
, pp. 292
-
-
Kranstuber, A.L.1
Del Rio, C.2
Biesiadecki, B.J.3
-
63
-
-
84865132307
-
An update on advanced glycation endproducts and atherosclerosis
-
Del Turco S, Basta G. An update on advanced glycation endproducts and atherosclerosis. Biofactors 38(4), 266-274 (2012).
-
(2012)
Biofactors
, vol.38
, Issue.4
, pp. 266-274
-
-
Del Turco, S.1
Basta, G.2
-
64
-
-
80051541139
-
Regulatory role of mitochondria in oxidative stress and atherosclerosis
-
Chang JC, Kou SJ, Lin WT, Liu CS. Regulatory role of mitochondria in oxidative stress and atherosclerosis. World J. Cardiol. 2(6), 150-159 (2010).
-
(2010)
World J. Cardiol
, vol.2
, Issue.6
, pp. 150-159
-
-
Chang, J.C.1
Kou, S.J.2
Lin, W.T.3
Liu, C.S.4
-
65
-
-
33646435289
-
The ligand/RAGE axis: Lighting the fuse and igniting vascular stress
-
Yan S, Naka Y, Hudson B et al. The ligand/RAGE axis: lighting the fuse and igniting vascular stress. Curr. Atheroscler. Rep. 8(3), 232-239 (2006). (Pubitemid 43676327)
-
(2006)
Current Atherosclerosis Reports
, vol.8
, Issue.3
, pp. 232-239
-
-
Yan, S.F.1
Naka, Y.2
Hudson, B.I.3
Herold, K.4
Yan, S.D.5
Ramasamy, R.6
Schmidt, A.M.7
-
66
-
-
84866761990
-
Ischemia-induced hyperglycemia: Consequences, neuroendocrine regulation, and a role for RAGE
-
Weil Z. Ischemia-induced hyperglycemia: consequences, neuroendocrine regulation, and a role for RAGE. Horm. Behav. 62(3), 280-285 (2012).
-
(2012)
Horm. Behav
, vol.62
, Issue.3
, pp. 280-285
-
-
Weil, Z.1
-
67
-
-
84856281473
-
RAGE mediates vascular injury and inflammation after global cerebral ischemia
-
Kamide T, Kitao Y, Takeichi T et al. RAGE mediates vascular injury and inflammation after global cerebral ischemia. Neurochem. Int. 60(3), 220-228 (2012).
-
(2012)
Neurochem. Int
, vol.60
, Issue.3
, pp. 220-228
-
-
Kamide, T.1
Kitao, Y.2
Takeichi, T.3
-
68
-
-
84859761969
-
The complexity of sporadic alzheimer's disease pathogenesis: The role of RAGE as therapeutic target to promote neuroprotection by inhibiting neurovascular dysfunction
-
doi:10.1155/2012/734956 Epub ahead of print
-
Perrone L, Sbai O, Nawroth P, Bierhaus A. The complexity of sporadic alzheimer's disease pathogenesis: the role of RAGE as therapeutic target to promote neuroprotection by inhibiting neurovascular dysfunction. Int. J. Alzheimers Dis. doi:10.1155/2012/734956 (2012) (Epub ahead of print).
-
(2012)
Int. J. Alzheimers Dis
-
-
Perrone, L.1
Sbai, O.2
Nawroth, P.3
Bierhaus, A.4
-
69
-
-
84861866738
-
RAGE signaling by alveolar macrophages influences tobacco smoke-induced inflammation
-
Robinson A, Johnson K, Bennion B, Reynolds P. RAGE signaling by alveolar macrophages influences tobacco smoke-induced inflammation. Am. J. Lung Cell Mol. Physiol. 302(11), L1192-L1199 (2012).
-
(2012)
Am. J. Lung Cell Mol. Physiol
, vol.302
, Issue.11
-
-
Robinson, A.1
Johnson, K.2
Bennion, B.3
Reynolds, P.4
-
70
-
-
84860881446
-
Studies of gene variants related to inflammation, oxidative stress, dyslipidemia, and obesity: Implications for a nutrigenetic approach
-
doi:10.1155/2011/497401 Epub ahead of print
-
Curti M, Jacob P, Borges M, Rogero M, Ferreira S. Studies of gene variants related to inflammation, oxidative stress, dyslipidemia, and obesity: implications for a nutrigenetic approach. J. Obes. doi:10.1155/2011/497401 (2011) (Epub ahead of print).
-
(2011)
J. Obes
-
-
Curti, M.1
Jacob, P.2
Borges, M.3
Rogero, M.4
Ferreira, S.5
-
71
-
-
33845866857
-
Inflammation and metabolic disorders
-
DOI 10.1038/nature05485, PII NATURE05485
-
Hotamisligil GS. Inflammation and metabolic disorders. Nature 444(7121), 860-867 (2006). (Pubitemid 46024993)
-
(2006)
Nature
, vol.444
, Issue.7121
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
72
-
-
70349118256
-
Islet endothelial activation and oxidative stress gene expression is reduced by IL-1Ra treatment in the type 2 diabetic GK rat
-
Lacraz G, Giroix M, Kassis N et al. Islet endothelial activation and oxidative stress gene expression is reduced by IL-1Ra treatment in the type 2 diabetic GK rat. PLoS ONE 4(9), e6963 (2009).
-
(2009)
PLoS ONE
, vol.4
, Issue.9
-
-
Lacraz, G.1
Giroix, M.2
Kassis, N.3
-
73
-
-
78649498271
-
The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity
-
Stienstra R, Joosten L, Koenen T et al. The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity. Cell Metab. 12(6), 593-605 (2010).
-
(2010)
Cell Metab
, vol.12
, Issue.6
, pp. 593-605
-
-
Stienstra, R.1
Joosten, L.2
Koenen, T.3
-
74
-
-
36849045915
-
The inflammasome: A danger sensing complex triggering innate immunity
-
DOI 10.1016/j.coi.2007.09.002, PII S0952791507001677, Autoimmunity / Allergy and Hypersenditivity
-
Petrilli V, Dostert C, Muruve DA, Tschopp J. The inflammasome: a danger sensing complex triggering innate immunity. Curr. Opin. Immunol. 19(6), 615-622 (2007). (Pubitemid 350236810)
-
(2007)
Current Opinion in Immunology
, vol.19
, Issue.6
, pp. 615-622
-
-
Petrilli, V.1
Dostert, C.2
Muruve, D.A.3
Tschopp, J.4
-
75
-
-
84855432021
-
The inflammasome puts obesity in the danger zone
-
Stienstra R, Tack CJ, Kanneganti TD, Joosten LA, Netea MG. The inflammasome puts obesity in the danger zone. Cell Metab. 15(1), 10-18 (2012).
-
(2012)
Cell Metab
, vol.15
, Issue.1
, pp. 10-18
-
-
Stienstra, R.1
Tack, C.J.2
Kanneganti, T.D.3
Joosten, L.A.4
Netea, M.G.5
-
76
-
-
84858630049
-
A role for the NLRP3 inflammasome in metabolic diseases-did Warburg miss inflammation?
-
Wen H, Ting J, O'Neill L. A role for the NLRP3 inflammasome in metabolic diseases-did Warburg miss inflammation? Nat. Immunol. 13(4), 352-357 (2012).
-
(2012)
Nat Immunol
, vol.13
, Issue.4
, pp. 352-357
-
-
Wen, H.1
Ting, J.2
O'Neill, L.3
-
77
-
-
79960143543
-
Increased IL-1b activation, the culprit not only for defective insulin secretion but also for insulin resistance?
-
Böni-Schnetzler M, Donath M. Increased IL-1b activation, the culprit not only for defective insulin secretion but also for insulin resistance? Cell Res. 21(7), 995-997 (2011).
-
(2011)
Cell Res
, vol.21
, Issue.7
, pp. 995-997
-
-
Böni-Schnetzler, M.1
Donath, M.2
-
78
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
DOI 10.1172/JCI200319451
-
Xu H, Barnes GT, Yang Q et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest. 112(12), 1821-1830 (2003). (Pubitemid 38063705)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
79
-
-
84856722119
-
Hyperlipidemia stimulates the extracellular release of the nuclear high mobility group box 1 protein
-
Haraba R, Suica V, Uyy E, Ivan L, Antohe F. Hyperlipidemia stimulates the extracellular release of the nuclear high mobility group box 1 protein. Cell Tissue Res. 346(3), 361-368 (2011).
-
(2011)
Cell Tissue Res
, vol.346
, Issue.3
, pp. 361-368
-
-
Haraba, R.1
Suica, V.2
Uyy, E.3
Ivan, L.4
Antohe, F.5
-
80
-
-
84866129230
-
Skeletal muscle-specific overproduction of constitutively activated c-Jun N-terminal kinase (JNK) induces insulin resistance in mice
-
Henstridge D, Bruce C, Pang C et al. Skeletal muscle-specific overproduction of constitutively activated c-Jun N-terminal kinase (JNK) induces insulin resistance in mice. Diabetologia 55(10), 2769-2778 (2012).
-
(2012)
Diabetologia
, vol.55
, Issue.10
, pp. 2769-2778
-
-
Henstridge, D.1
Bruce, C.2
Pang, C.3
-
81
-
-
0033579210
-
Both p38alpha(MAPK) and JNK/SAPK pathways are important for induction of nitric-oxide synthase by interleukin-1beta in rat glomerular mesangial cells
-
Guan Z, Buckman S, Springer L, Morrison A. Both p38alpha(MAPK) and JNK/SAPK pathways are important for induction of nitric-oxide synthase by interleukin-1beta in rat glomerular mesangial cells. J. Biol. Chem. 274(51), 36200-36206 (1999).
-
(1999)
J. Biol. Chem
, vol.274
, Issue.51
, pp. 36200-36206
-
-
Guan, Z.1
Buckman, S.2
Springer, L.3
Morrison, A.4
-
82
-
-
84859269961
-
Differential usage of NF-B activating signals by IL-1b and TNF-A in pancreatic beta cells
-
Ortis F, Miani M, Colli M et al. Differential usage of NF-B activating signals by IL-1b and TNF-a in pancreatic beta cells. FEBS Lett. 586, 984-989 (2012).
-
(2012)
FEBS Lett
, vol.586
, pp. 984-989
-
-
Ortis, F.1
Miani, M.2
Colli, M.3
-
83
-
-
84879459608
-
Inflammation, cytokines and insulin resistance: A clinical perspective
-
Wieser V, Moschen A, Tilg H. Inflammation, cytokines and insulin resistance: a clinical perspective. Arch. Immunol. Ther. Exp. 61(2), 119-125 (2013).
-
(2013)
Arch. Immunol. Ther. Exp
, vol.61
, Issue.2
, pp. 119-125
-
-
Wieser, V.1
Moschen, A.2
Tilg, H.3
-
84
-
-
77951831569
-
Accelerated increase in serum interleukin-1 receptor antagonist starts 6 years before diagnosis of type 2 diabetes: Whitehall II prospective cohort study
-
Carstensen M, Herder C, Kivimaki M et al. Accelerated increase in serum interleukin-1 receptor antagonist starts 6 years before diagnosis of type 2 diabetes: Whitehall II prospective cohort study. Diabetes 59(5), 1222-1227 (2010).
-
(2010)
Diabetes
, vol.59
, Issue.5
, pp. 1222-1227
-
-
Carstensen, M.1
Herder, C.2
Kivimaki, M.3
-
85
-
-
84865615147
-
The emerging challenge in diabetes: The "metabolic memory
-
Ceriello A. The emerging challenge in diabetes: the "metabolic memory". Vascul. Pharmacol. 57(5-6), 133-138 (2012).
-
(2012)
Vascul. Pharmacol
, vol.57
, Issue.5-6
, pp. 133-138
-
-
Ceriello, A.1
-
86
-
-
33751375903
-
Cardiovascular disease
-
Jamison DT, Breman JG, Measham AR et al. (Eds). World Bank, Washington DC, USA
-
Gaziano T, Reddy KS, Paccaud F, Horton S, Chaturvedi V. Cardiovascular disease. In: Disease Control Priorities in Developing Countries. Jamison DT, Breman JG, Measham AR et al. (Eds). World Bank, Washington DC, USA, 646-662 (2006).
-
(2006)
Disease Control Priorities in Developing Countries
, pp. 646-662
-
-
Gaziano, T.1
Reddy, K.S.2
Paccaud, F.3
Horton, S.4
Chaturvedi, V.5
-
87
-
-
84866464706
-
MicroRNA-145 targeted therapy reduces atherosclerosis
-
Lovren F, Pan Y, Quan A et al. MicroRNA-145 targeted therapy reduces atherosclerosis. Circulation 126(11 Suppl. 1), S81-S90 (2012).
-
(2012)
Circulation
, vol.126
, Issue.11 SUPPL. 1
-
-
Lovren, F.1
Pan, Y.2
Quan, A.3
-
88
-
-
84868628390
-
Impaired response of FGF-23 to oral phosphate in patients with Type 2 diabetes: A possible mechanism of atherosclerosis
-
Yoda K, Imanishi Y, Yoda M et al. Impaired response of FGF-23 to oral phosphate in patients with Type 2 diabetes: a possible mechanism of atherosclerosis. J. Clin. Endocrinol. Metab. 97(11), E2036-E2043 (2012).
-
(2012)
J. Clin. Endocrinol. Metab
, vol.97
, Issue.11
-
-
Yoda, K.1
Imanishi, Y.2
Yoda, M.3
-
89
-
-
84866002538
-
Dynamic T cell-APC interactions sustain chronic inflammation in atherosclerosis
-
Koltsova E, Garcia Z, Chodaczek G et al. Dynamic T cell-APC interactions sustain chronic inflammation in atherosclerosis. J. Clin. Invest. 122(9), 3114-3126 (2012).
-
(2012)
J. Clin. Invest
, vol.122
, Issue.9
, pp. 3114-3126
-
-
Koltsova, E.1
Garcia, Z.2
Chodaczek, G.3
-
90
-
-
64549109737
-
Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding
-
Chamberlain J, Francis S, Brookes Z et al. Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding. PLoS ONE 4(4), e5073 (2009).
-
(2009)
PLoS ONE
, vol.4
, Issue.4
-
-
Chamberlain, J.1
Francis, S.2
Brookes, Z.3
-
91
-
-
0037388984
-
Lack of interleukin-1ß decreases the severity of atherosclerosis in apoE-deficient mice
-
DOI 10.1161/01.ATV.0000064374.15232.C3
-
Kirii H, Niwa T, Yamada Y et al. Lack of interleukin-1beta decreases the severity of atherosclerosis in ApoE-deficient mice. Arterioscler. Thromb. Vasc. Biol. 23(4), 656-660 (2003). (Pubitemid 36438080)
-
(2003)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.23
, Issue.4
, pp. 656-660
-
-
Kirii, H.1
Niwa, T.2
Yamada, Y.3
Wada, H.4
Saito, K.5
Iwakura, Y.6
Asano, M.7
Moriwaki, H.8
Seishima, M.9
-
92
-
-
66349089266
-
IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation
-
Ben-Sasson S, Hu-Li J, Quiel J et al. IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation. Proc. Natl Acad. Sci. USA 106(17), 7119-7124 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, Issue.17
, pp. 7119-7124
-
-
Ben-Sasson, S.1
Hu-Li, J.2
Quiel, J.3
-
93
-
-
52449114737
-
Vascular cells contribute to atherosclerosis by cytokine-and innate-immunity-related inflammatory mechanisms
-
Loppnow H, Werdan K, Buerke M. Vascular cells contribute to atherosclerosis by cytokine-and innate-immunity-related inflammatory mechanisms. Innate Immun. 14(2), 63-87 (2008).
-
(2008)
Innate Immun
, vol.14
, Issue.2
, pp. 63-87
-
-
Loppnow, H.1
Werdan, K.2
Buerke, M.3
-
94
-
-
16444380674
-
Atherosclerotic abdominal aortic aneurysm and the interaction between autologous human plaque-derived vascular smooth muscle cells, type 1 NKT, and helper T cells
-
DOI 10.1161/01.RES.0000160543.84254.f1
-
Chan W, Pejnovic N, Hamilton H et al. Atherosclerotic abdominal aortic aneurysm and the interaction between autologous human plaque-derived vascular smooth muscle cells, type 1 NKT, and helper T cells. Circ. Res. 96(6), 675-683 (2005). (Pubitemid 40478335)
-
(2005)
Circulation Research
, vol.96
, Issue.6
, pp. 675-683
-
-
Chan, W.L.1
Pejnovic, N.2
Hamilton, H.3
Liew, T.V.4
Popadic, D.5
Poggi, A.6
Khan, S.M.7
-
95
-
-
0032080628
-
Leukocyte-endothelial interaction is augmented by high glucose concentrations and hyperglycemia in a NF-kB-dependent fashion
-
Morigi M, Angioletti S, Imberti B et al. Leukocyte-endothelial interaction is augmented by high glucose concentrations and hyperglycemia in a NF-kB-dependent fashion. J. Clin. Invest. 101(9), 1905-1915 (1998). (Pubitemid 28226110)
-
(1998)
Journal of Clinical Investigation
, vol.101
, Issue.9
, pp. 1905-1915
-
-
Morigi, M.1
Angioletti, S.2
Imberti, B.3
Donadelli, R.4
Micheletti, G.5
Figliuzzi, M.6
Remuzzi, A.7
Zoja, C.8
Remuzzi, G.9
-
96
-
-
79955621179
-
RAGE biology, atherosclerosis and diabetes
-
Barlovic DP, Soro-Paavonen A, Jandeleit-Dahm KA. RAGE biology, atherosclerosis and diabetes. Clin. Sci. (Lond.) 121(2), 43-55 (2011).
-
(2011)
Clin. Sci. (Lond.)
, vol.121
, Issue.2
, pp. 43-55
-
-
Barlovic, D.P.1
Soro-Paavonen, A.2
Jandeleit-Dahm, K.A.3
-
97
-
-
38149078193
-
Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/-mice
-
Harja E, Bu DX, Hudson BI et al. Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/-mice. J. Clin. Invest. 118(1), 183-194 (2008).
-
(2008)
J. Clin. Invest
, vol.118
, Issue.1
, pp. 183-194
-
-
Harja, E.1
Bu, D.X.2
Hudson, B.I.3
-
98
-
-
0031717894
-
Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts
-
DOI 10.1038/2012
-
Park L, Raman KG, Lee KJ et al. Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts. Nat. Med. 4(9), 1025-1031 (1998). (Pubitemid 28417334)
-
(1998)
Nature Medicine
, vol.4
, Issue.9
, pp. 1025-1031
-
-
Park, L.1
Raman, K.G.2
Lee, K.J.3
Lu, Y.4
Ferran Jr., L.J.5
Choe, W.S.6
Stern, D.7
Schmidt, A.M.8
-
99
-
-
52449094718
-
AGE/RAGE produces endothelial dysfunction in coronary arterioles in Type 2 diabetic mice
-
Gao X, Zhang H, Schmidt AM, Zhang C. AGE/RAGE produces endothelial dysfunction in coronary arterioles in Type 2 diabetic mice. Am. J. Physiol. Heart Circ. Physiol. 295(2), H491-498 (2008).
-
(2008)
Am. J. Physiol. Heart Circ. Physiol
, vol.295
, Issue.2
-
-
Gao, X.1
Zhang, H.2
Schmidt, A.M.3
Zhang, C.4
-
100
-
-
52749084063
-
Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes
-
Soro-Paavonen A, Watson AM, Li J et al. Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes. Diabetes 57(9), 2461-2469 (2008).
-
(2008)
Diabetes
, vol.57
, Issue.9
, pp. 2461-2469
-
-
Soro-Paavonen, A.1
Watson, A.M.2
Li, J.3
-
101
-
-
77953525199
-
Receptor for advanced glycation end-products (RAGE) regulation of adiposity and adiponectin is associated with atherogenesis in apoE-deficient mouse
-
Ueno H, Koyama H, Shoji T et al. Receptor for advanced glycation end-products (RAGE) regulation of adiposity and adiponectin is associated with atherogenesis in apoE-deficient mouse. Atherosclerosis 211(2), 431-436 (2010).
-
(2010)
Atherosclerosis
, vol.211
, Issue.2
, pp. 431-436
-
-
Ueno, H.1
Koyama, H.2
Shoji, T.3
-
102
-
-
8344275053
-
Inhibition of tumor necrosis factor-α reduces atherosclerosis in apolipoprotein E knockout mice
-
DOI 10.1161/01.ATV.0000143933.20616.1b
-
Branen L, Hovgaard L, Nitulescu M, Bengtsson E, Nilsson J, Jovinge S. Inhibition of tumor necrosis factor-alpha reduces atherosclerosis in apolipoprotein E knockout mice. Arterioscler. Thromb. Vasc. Biol. 24(11), 2137-2142 (2004). (Pubitemid 39482442)
-
(2004)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.24
, Issue.11
, pp. 2137-2142
-
-
Branen, L.1
Hovgaard, L.2
Nitulescu, M.3
Bengtsson, E.4
Nilsson, J.5
Jovinge, S.6
-
103
-
-
67650069731
-
Association between circulating soluble receptor for advanced glycation end products and atherosclerosis: Observations from the Dallas Heart Study
-
Lindsey JB, De Lemos JA, Cipollone F et al. Association between circulating soluble receptor for advanced glycation end products and atherosclerosis: observations from the Dallas Heart Study. Diabetes Care 32(7), 1218-1220 (2009).
-
(2009)
Diabetes Care
, vol.32
, Issue.7
, pp. 1218-1220
-
-
Lindsey, J.B.1
De Lemos, J.A.2
Cipollone, F.3
-
104
-
-
79955066389
-
Role of advanced glycation end product receptors in the pathogenesis of diabetic retinopathy
-
Al-Mesallamy HO, Hammad LN, El-Mamoun TA, Khalil BM. Role of advanced glycation end product receptors in the pathogenesis of diabetic retinopathy. J. Diabetes Complications 25(3), 168-174 (2011).
-
(2011)
J. Diabetes Complications
, vol.25
, Issue.3
, pp. 168-174
-
-
Al-Mesallamy, H.O.1
Hammad, L.N.2
El-Mamoun, T.A.3
Khalil, B.M.4
-
105
-
-
77957243199
-
Soluble receptor of advanced glycation end products levels are related to ischaemic aetiology and extent of coronary disease in chronic heart failure patients, independent of advanced glycation end products levels: New roles for soluble RAGE
-
Raposeiras-Roubin S, Rodino-Janeiro BK, Grigorian-Shamagian L et al. Soluble receptor of advanced glycation end products levels are related to ischaemic aetiology and extent of coronary disease in chronic heart failure patients, independent of advanced glycation end products levels: new roles for soluble RAGE. Eur. J. Heart Fail. 12(10), 1092-1100 (2010).
-
(2010)
Eur. J. Heart Fail
, vol.12
, Issue.10
, pp. 1092-1100
-
-
Raposeiras-Roubin, S.1
Rodino-Janeiro, B.K.2
Grigorian-Shamagian, L.3
-
106
-
-
84879651810
-
Life after death: Targeting high mobility group box 1 in emergent cancer therapies
-
Guo ZS, Liu Z, Bartlett DL, Tang D, Lotze MT. Life after death: targeting high mobility group box 1 in emergent cancer therapies. Am. J. Cancer Res. 3(1), 1-20 (2013).
-
(2013)
Am. J. Cancer Res
, vol.3
, Issue.1
, pp. 1-20
-
-
Guo, Z.S.1
Liu, Z.2
Bartlett, D.L.3
Tang, D.4
Lotze, M.T.5
-
107
-
-
0042317299
-
Regulation of cyclooxygenase-2 expression in monocytes by ligation of the receptor for advanced glycation end products
-
DOI 10.1074/jbc.M302828200
-
Shanmugam N, Kim YS, Lanting L, Natarajan R. Regulation of cyclooxygenase-2 expression in monocytes by ligation of the receptor for advanced glycation end products. J. Biol. Chem. 278(37), 34834-34844 (2003). (Pubitemid 37102242)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.37
, pp. 34834-34844
-
-
Shanmugam, N.1
Kim, Y.S.2
Lanting, L.3
Natarajan, R.4
-
108
-
-
39549098128
-
RAGE signaling sustains inflammation and promotes tumor development
-
DOI 10.1084/jem.20070679
-
Gebhardt C, Riehl A, Durchdewald M et al. RAGE signaling sustains inflammation and promotes tumor development. J. Exp. Med. 205(2), 275-285 (2008). (Pubitemid 351281593)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.2
, pp. 275-285
-
-
Gebhardt, C.1
Riehl, A.2
Durchdewald, M.3
Nemeth, J.4
Furstenberger, G.5
Muller-Decker, K.6
Enk, A.7
Arnold, B.8
Bierhaus, A.9
Nawroth, P.P.10
Hess, J.11
Angel, P.12
-
109
-
-
53349173233
-
RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis
-
Turovskaya O, Foell D, Sinha P et al. RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis. Carcinogenesis 29(10), 2035-2043 (2008).
-
(2008)
Carcinogenesis
, vol.29
, Issue.10
, pp. 2035-2043
-
-
Turovskaya, O.1
Foell, D.2
Sinha, P.3
-
110
-
-
33646233778
-
Cytokines GM-CSF and IFNgamma administered by priming and post-chemotherapy cycling in recurrent ovarian cancer patients receiving carboplatin
-
Apte SM, Vadhan-Raj S, Cohen L et al. Cytokines, GM-CSF and IFNgamma administered by priming and post-chemotherapy cycling in recurrent ovarian cancer patients receiving carboplatin. J. Transl. Med. 4, 16 (2006).
-
(2006)
J. Transl. Med
, vol.4
, pp. 16
-
-
Apte, S.M.1
Vadhan-Raj, S.2
Cohen, L.3
-
111
-
-
33644759372
-
The role of interleukin 1 in growth and metastasis of human cancer xenografts
-
DOI 10.1158/1078-0432.CCR-05-1603
-
Elaraj DM, Weinreich DM, Varghese S et al. The role of interleukin 1 in growth and metastasis of human cancer xenografts. Clin. Cancer Res. 12(4), 1088-1096 (2006). (Pubitemid 43342496)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.4
, pp. 1088-1096
-
-
Elaraj, D.M.1
Weinreich, D.M.2
Varghese, S.3
Puhlmann, M.4
Hewitt, S.M.5
Carroll, N.M.6
Feldman, E.D.7
Turner, E.M.8
Alexander, H.R.9
-
112
-
-
77949889567
-
Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta
-
Okamoto M, Liu W, Luo Y et al. Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta. J. Biol. Chem. 285(9), 6477-6488 (2010).
-
(2010)
J. Biol. Chem
, vol.285
, Issue.9
, pp. 6477-6488
-
-
Okamoto, M.1
Liu, W.2
Luo, Y.3
-
113
-
-
0032581277
-
Role of HIF-1α in hypoxiamediated apoptosis, cell proliferation and tumour angiogenesis
-
DOI 10.1038/28867
-
Carmeliet P, Dor Y, Herbert JM et al. Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 394(6692), 485-490 (1998). (Pubitemid 28373960)
-
(1998)
Nature
, vol.394
, Issue.6692
, pp. 485-490
-
-
Carmeliet, P.1
Dor, Y.2
Herber, J.-M.3
Fukumura, D.4
Brusselmans, K.5
Dewerchin, M.6
Neeman, M.7
Bono, F.8
Abramovitch, R.9
Maxwell, P.10
Koch, C.J.11
Ratcliffe, P.12
Moons, L.13
Jain, R.K.14
Collen, D.15
Keshet, E.16
-
114
-
-
0029979369
-
Biologic basis for interleukin-1 in disease
-
Dinarello CA. Biologic basis for interleukin-1 in disease. Blood 87(6), 2095-2147 (1996). (Pubitemid 26086851)
-
(1996)
Blood
, vol.87
, Issue.6
, pp. 2095-2147
-
-
Dinarello, C.A.1
-
115
-
-
29144504335
-
+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1β-secreting cells
-
Song X, Krelin Y, Dvorkin T et al. CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1beta-secreting cells. J. Immunol. 175(12), 8200-8208 (2005). (Pubitemid 41798384)
-
(2005)
Journal of Immunology
, vol.175
, Issue.12
, pp. 8200-8208
-
-
Song, X.1
Krelin, Y.2
Dvorkin, T.3
Bjorkdahl, O.4
Segal, S.5
Dinarello, C.A.6
Voronov, E.7
Apte, R.N.8
-
116
-
-
0037207461
-
Interleukin-1β gene polymorphisms associated with hepatocellular carcinoma in hepatitis C virus infection
-
DOI 10.1053/jhep.2003.50017
-
Wang Y, Kato N, Hoshida Y et al. Interleukin-1beta gene polymorphisms associated with hepatocellular carcinoma in hepatitis C virus infection. Hepatology 37(1), 65-71 (2003). (Pubitemid 36042146)
-
(2003)
Hepatology
, vol.37
, Issue.1
, pp. 65-71
-
-
Wang, Y.1
Kato, N.2
Hoshida, Y.3
Yoshida, H.4
Taniguchi, H.5
Goto, T.6
Moriyama, M.7
Otsuka, M.8
Shiina, S.9
Shiratori, Y.10
Ito, Y.11
Omata, M.12
-
117
-
-
84866724935
-
IL1 receptor antagonist gene IL1-RN variable number of tandem repeats polymorphism and cancer risk: A literature review and meta-analysis
-
Zhang Y, Liu C, Peng H, Zhang J, Feng Q. IL1 receptor antagonist gene IL1-RN variable number of tandem repeats polymorphism and cancer risk: a literature review and meta-analysis. PLoS ONE 7(9), e46017 (2012).
-
(2012)
PLoS ONE
, vol.7
, Issue.9
-
-
Zhang, Y.1
Liu, C.2
Peng, H.3
Zhang, J.4
Feng, Q.5
-
118
-
-
50349091833
-
Gly82Ser polymorphism of the receptor for advanced glycation end products is associated with an increased risk of gastric cancer in a Chinese population
-
Gu H, Yang L, Sun Q et al. Gly82Ser polymorphism of the receptor for advanced glycation end products is associated with an increased risk of gastric cancer in a Chinese population. Clin. Cancer Res. 14(11), 3627-3632 (2008).
-
(2008)
Clin. Cancer Res
, vol.14
, Issue.11
, pp. 3627-3632
-
-
Gu, H.1
Yang, L.2
Sun, Q.3
-
119
-
-
77953716356
-
Soluble receptor for advanced glycation end-products (sRAGE) and polymorphisms of RAGE and glyoxalase i genes in patients with pancreas cancer
-
Krechler T, Jachymova M, Mestek O, Zak A, Zima T, Kalousova M. Soluble receptor for advanced glycation end-products (sRAGE) and polymorphisms of RAGE and glyoxalase I genes in patients with pancreas cancer. Clin. Biochem. 43(10-11), 882-886 (2010).
-
(2010)
Clin. Biochem
, vol.43
, Issue.10-11
, pp. 882-886
-
-
Krechler, T.1
Jachymova, M.2
Mestek, O.3
Zak, A.4
Zima, T.5
Kalousova, M.6
-
120
-
-
36849057047
-
Receptor for advanced glycation end products (RAGE) - Soluble form (sRAGE) and gene polymorphisms in patients with breast cancer
-
DOI 10.1080/07357900701560521, PII 785043774
-
Tesarova P, Kalousova M, Jachymova M, Mestek O, Petruzelka L, Zima T. Receptor for advanced glycation end products (RAGE)-soluble form (sRAGE) and gene polymorphisms in patients with breast cancer. Cancer Invest. 25(8), 720-725 (2007). (Pubitemid 350223177)
-
(2007)
Cancer Investigation
, vol.25
, Issue.8
, pp. 720-725
-
-
Tesarova, P.1
Kalousova, M.2
Jachymova, M.3
Mestek, O.4
Petruzelka, L.5
Zima, T.6
-
121
-
-
84875660089
-
The immunobiology of the receptor of advanced glycation end-products: Trends and challenges
-
Gonzalez I, Romero J, Rodriguez BL, Perez-Castro R, Rojas A. The immunobiology of the receptor of advanced glycation end-products: trends and challenges. Immunobiology 218(5), 790-797 (2012).
-
(2012)
Immunobiology
, vol.218
, Issue.5
, pp. 790-797
-
-
Gonzalez, I.1
Romero, J.2
Rodriguez, B.L.3
Perez-Castro, R.4
Rojas, A.5
-
122
-
-
17144380822
-
The metabolic syndrome
-
DOI 10.1016/S0140-6736(05)66378-7
-
Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet 365(9468), 1415-1428 (2005). (Pubitemid 40523737)
-
(2005)
Lancet
, vol.365
, Issue.9468
, pp. 1415-1428
-
-
Eckel, R.H.1
Grundy, S.M.2
Zimmet, P.Z.3
-
123
-
-
80053408094
-
Fatty acids, obesity, and insulin resistance: Time for a reevaluation
-
Karpe F, Dickmann JR, Frayn KN. Fatty acids, obesity, and insulin resistance: time for a reevaluation. Diabetes 60(10), 2441-2449 (2011).
-
(2011)
Diabetes
, vol.60
, Issue.10
, pp. 2441-2449
-
-
Karpe, F.1
Dickmann, J.R.2
Frayn, K.N.3
-
124
-
-
0036348363
-
Ectopic fat accumulation: An important cause of insulin resistance in humans
-
Yki-Jarvinen H. Ectopic fat accumulation: an important cause of insulin resistance in humans. J. R. Soc. Med. 95(Suppl. 42), 39-45 (2002). (Pubitemid 34879130)
-
(2002)
Journal of the Royal Society of Medicine, Supplement
, vol.95
, Issue.42
, pp. 39-45
-
-
Yki-Jarvinen, H.1
-
125
-
-
34548186474
-
The importance of free fatty acids in the development of Type 2 diabetes
-
DOI 10.1111/j.1464-5491.2007.02186.x
-
Wilding JP. The importance of free fatty acids in the development of Type 2 diabetes. Diabet. Med. 24(9), 934-945 (2007). (Pubitemid 47304378)
-
(2007)
Diabetic Medicine
, vol.24
, Issue.9
, pp. 934-945
-
-
Wilding, J.P.H.1
-
126
-
-
0043253165
-
The mammalian fatty acid-binding protein multigene family: Molecular and genetic insights into function
-
DOI 10.1016/S1043-2760(00)00257-5, PII S1043276000002575
-
Hertzel AV, Bernlohr DA. The mammalian fatty acid-binding protein multigene family: molecular and genetic insights into function. Trends Endocrinol. Metab. 11(5), 175-180 (2000). (Pubitemid 30457137)
-
(2000)
Trends in Endocrinology and Metabolism
, vol.11
, Issue.5
, pp. 175-180
-
-
Vogel Hertzel, A.1
Bernlohr, D.A.2
-
127
-
-
34547447341
-
Blocking fatty acids' mystery tour: A therapy for metabolic syndrome?
-
DOI 10.1016/j.cmet.2007.07.008, PII S1550413107001969
-
Roden M. Blocking fatty acids' mystery tour: a therapy for metabolic syndrome? Cell Metab. 6(2), 89-91 (2007). (Pubitemid 47163626)
-
(2007)
Cell Metabolism
, vol.6
, Issue.2
, pp. 89-91
-
-
Roden, M.1
-
128
-
-
0029847504
-
Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein
-
Hotamisligil G, Johnson R, Distel R, Ellis R, Papaioannou V, Spiegelman B. Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein. Science 274(5291), 1377-1379 (1990).
-
(1990)
Science
, vol.274
, Issue.5291
, pp. 1377-1379
-
-
Hotamisligil, G.1
Johnson, R.2
Distel, R.3
Ellis, R.4
Papaioannou, V.5
Spiegelman, B.6
-
129
-
-
11144257720
-
-/- mice
-
DOI 10.1152/ajpendo.00256.2004
-
Baar RA, Dingfelder CS, Smith LA et al. Investigation of in vivo fatty acid metabolism in AFABP/aP2(-/-) mice. Am. J. Physiol. Endocrinol. Metab. 288(1), E187-E193 (2005). (Pubitemid 40023806)
-
(2005)
American Journal of Physiology - Endocrinology and Metabolism
, vol.288
, Issue.1
-
-
Baar, R.A.1
Dingfelder, C.S.2
Smith, L.A.3
Bernlohr, D.A.4
Wu, C.5
Lange, A.J.6
Parks, E.J.7
-
130
-
-
16844379483
-
The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity: Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor gamma and IkappaB kinase activities
-
Makowski L, Brittingham K, Reynolds J, Suttles J, Hotamisligil G. The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity: macrophage expression of aP2 impacts peroxisome proliferator-activated receptor gamma and IkappaB kinase activities. J. Biol. Chem. 13, 12888-12895 (2005).
-
(2005)
J. Biol. Chem
, vol.13
, pp. 12888-12895
-
-
Makowski, L.1
Brittingham, K.2
Reynolds, J.3
Suttles, J.4
Hotamisligil, G.5
-
132
-
-
34250201866
-
Continuous nucleocytoplasmic shuttling underlies transcriptional activation of PPARγ by FABP4
-
DOI 10.1021/bi700047a
-
Ayers SD, Nedrow KL, Gillilan RE, Noy N. Continuous nucleocytoplasmic shuttling underlies transcriptional activation of PPARgamma by FABP4. Biochemistry 46(23), 6744-6752 (2007). (Pubitemid 46906405)
-
(2007)
Biochemistry
, vol.46
, Issue.23
, pp. 6744-6752
-
-
Avers, S.D.1
Nedrow, K.L.2
Gillilan, R.E.3
Noy, N.4
-
133
-
-
34548515270
-
Structural basis for activation of fatty acid-binding protein 4
-
DOI 10.1016/j.jmb.2007.07.040, PII S0022283607009680
-
Gillilan RE, Ayers SD, Noy N. Structural basis for activation of fatty acid-binding protein 4. J. Mol. Biol. 372(5), 1246-1260 (2007). (Pubitemid 47374720)
-
(2007)
Journal of Molecular Biology
, vol.372
, Issue.5
, pp. 1246-1260
-
-
Gillilan, R.E.1
Ayers, S.D.2
Noy, N.3
-
134
-
-
1842610797
-
Genetic variation in fatty acid-binding protein-4 and peroxisome proliferator-activated receptor γ interactively influence insulin sensitivity and body composition in males
-
DOI 10.1016/j.metabol.2003.10.010
-
Damcott C, Moffett S, Feingold E et al. Genetic variation in fatty acid-binding protein-4 and peroxisome proliferator-activated receptor gamma interactively influence insulin sensitivity and body composition in males. Metabolism 53(3), 303-309 (2004). (Pubitemid 38684689)
-
(2004)
Metabolism: Clinical and Experimental
, vol.53
, Issue.3
, pp. 303-309
-
-
Damcott, C.M.1
Moffett, S.P.2
Feingold, E.3
Barmada, M.M.4
Marshall, J.A.5
Hamman, R.F.6
Ferrell, R.E.7
-
135
-
-
42449097289
-
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
-
DOI 10.1038/nrm2391, PII NRM2391
-
Guilherme A, Virbasius J, Puri V, Czech M. Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat. Rev. Mol. Cell Biol. 9(5), 367-377 (2008). (Pubitemid 351574198)
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, Issue.5
, pp. 367-377
-
-
Guilherme, A.1
Virbasius, J.V.2
Puri, V.3
Czech, M.P.4
-
136
-
-
0036779687
-
Emerging roles of PPARs in inflammation and immunity
-
DOI 10.1038/nri912
-
Daynes RA, Jones DC. Emerging roles of PPARs in inflammation and immunity. Nat. Rev. Immunol. 2(10), 748-759 (2002). (Pubitemid 37328715)
-
(2002)
Nature Reviews Immunology
, vol.2
, Issue.10
, pp. 748-759
-
-
Daynes, R.A.1
Jones, D.C.2
-
137
-
-
4544342570
-
Nuclear factor-kappaB: The enemy within
-
Aggarwal BB. Nuclear factor-kappaB: the enemy within. Cancer Cell 6(3), 203-208 (2004).
-
(2004)
Cancer Cell
, vol.6
, Issue.3
, pp. 203-208
-
-
Aggarwal, B.B.1
-
138
-
-
84868355178
-
FABP4 dynamics in obesity: Discrepancies in adipose tissue and liver expression regarding circulating plasma levels
-
Queipo-Ortuno MI, Escote X, Ceperuelo-Mallafre V et al. FABP4 dynamics in obesity: discrepancies in adipose tissue and liver expression regarding circulating plasma levels. PLoS ONE 7(11), e48605 (2012).
-
(2012)
PLoS ONE
, vol.7
, Issue.11
-
-
Queipo-Ortuno, M.I.1
Escote, X.2
Ceperuelo-Mallafre, V.3
-
139
-
-
0025676428
-
Insulin receptor tyrosine kinase-catalyzed phosphorylation of 422(aP2) protein: Substrate activation by long-chain fatty acid
-
Hresko RC, Hoffman RD, Flores-Riveros JR, Lane MD. Insulin receptor tyrosine kinase-catalyzed phosphorylation of 422(aP2) protein. Substrate activation by long-chain fatty acid. J. Biol. Chem. 265(34), 21075-21085 (1990). (Pubitemid 120014123)
-
(1990)
Journal of Biological Chemistry
, vol.265
, Issue.34
, pp. 21075-21085
-
-
Hresko, R.C.1
Hoffman, R.D.2
Flores-Riveros, J.R.3
Lane, M.D.4
-
140
-
-
84862252814
-
Fatty acid-binding protein 4 impairs the insulin-dependent nitric oxide pathway in vascular endothelial cells
-
Aragonès G, Saavedra P, Heras M, Cabré A, Girona J, Masana L. Fatty acid-binding protein 4 impairs the insulin-dependent nitric oxide pathway in vascular endothelial cells. Cardiovasular. Diabetol. 11(1), 72 (2012).
-
(2012)
Cardiovasular. Diabetol
, vol.11
, Issue.1
, pp. 72
-
-
Aragonès, G.1
Saavedra, P.2
Heras, M.3
Cabré, A.4
Girona, J.5
Masana, L.6
-
141
-
-
84866410518
-
Elevation of fatty acid-binding protein 4 is predisposed by family history of hypertension and contributes to blood pressure elevation
-
Ota H, Furuhashi M, Ishimura S et al. Elevation of fatty acid-binding protein 4 is predisposed by family history of hypertension and contributes to blood pressure elevation. Am. J. Hypertens. 25(10), 1124-1130 (2012).
-
(2012)
Am. J. Hypertens
, vol.25
, Issue.10
, pp. 1124-1130
-
-
Ota, H.1
Furuhashi, M.2
Ishimura, S.3
-
142
-
-
84872166765
-
Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis
-
Odegaard JI, Chawla A. Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis. Science 339(6116), 172-177 (2013).
-
(2013)
Science
, vol.339
, Issue.6116
, pp. 172-177
-
-
Odegaard, J.I.1
Chawla, A.2
-
143
-
-
79955687594
-
Receptor mediated elevation in FABP4 levels by advanced glycation end products induces cholesterol and triacylglycerol accumulation in THP-1 macrophages
-
Wang X, Yang K, He Y, Lu L, Shen W. Receptor mediated elevation in FABP4 levels by advanced glycation end products induces cholesterol and triacylglycerol accumulation in THP-1 macrophages. Lipids 46(6), 479-486 (2011).
-
(2011)
Lipids
, vol.46
, Issue.6
, pp. 479-486
-
-
Wang, X.1
Yang, K.2
He, Y.3
Lu, L.4
Shen, W.5
-
144
-
-
66349128493
-
Serum fatty acid binding protein 4, free fatty acids, and metabolic risk markers
-
Karakas SE, Almario RU, Kim K. Serum fatty acid binding protein 4, free fatty acids, and metabolic risk markers. Metabolism 58(7), 1002-1007 (2009).
-
(2009)
Metabolism
, vol.58
, Issue.7
, pp. 1002-1007
-
-
Karakas, S.E.1
Almario, R.U.2
Kim, K.3
-
145
-
-
84872480987
-
Interleukin-1beta regulates fat-liver crosstalk in obesity by auto-paracrine modulation of adipose tissue inflammation and expandability
-
Nov O, Shapiro H, Ovadia H et al. Interleukin-1beta regulates fat-liver crosstalk in obesity by auto-paracrine modulation of adipose tissue inflammation and expandability. PLoS ONE 8(1), e53626 (2013).
-
(2013)
PLoS ONE
, vol.8
, Issue.1
-
-
Nov, O.1
Shapiro, H.2
Ovadia, H.3
-
146
-
-
33746736936
-
Long-term treatment with interleukin-1β induces insulin resistance in murine and human adipocytes
-
DOI 10.1007/s00125-006-0335-z
-
Lagathu C, Yvan-Charvet L, Bastard J et al. Long-term treatment with interleukin-1beta induces insulin resistance in murine and human adipocytes. Diabetologia 49(9), 2162-2173 (2006). (Pubitemid 44168485)
-
(2006)
Diabetologia
, vol.49
, Issue.9
, pp. 2162-2173
-
-
Lagathu, C.1
Yvan-Charvet, L.2
Bastard, J.-P.3
Maachi, M.4
Quignard-Boulange, A.5
Capeau, J.6
Caron, M.7
-
147
-
-
34047187449
-
The Interleukin-1 receptor antagonist is a direct target gene of PPARα in liver
-
DOI 10.1016/j.jhep.2006.11.019, PII S0168827806006726
-
Stienstra R, Mandard S, Tan NS et al. The interleukin-1 receptor antagonist is a direct target gene of PPARalpha in liver. J. Hepatol. 46(5), 869-877 (2007). (Pubitemid 46529035)
-
(2007)
Journal of Hepatology
, vol.46
, Issue.5
, pp. 869-877
-
-
Stienstra, R.1
Mandard, S.2
Tan, N.S.3
Wahli, W.4
Trautwein, C.5
Richardson, T.A.6
Lichtenauer-Kaligis, E.7
Kersten, S.8
Muller, M.9
-
148
-
-
41649093318
-
Inflammatory mechanisms in the regulation of insulin resistance
-
DOI 10.2119/2007-00119.Tilg
-
Tilg H, Moschen AR. Inflammatory mechanisms in the regulation of insulin resistance. Mol. Med. 14(3-4), 222-231 (2008). (Pubitemid 351481853)
-
(2008)
Molecular Medicine
, vol.14
, Issue.3-4
, pp. 222-231
-
-
Tilg, H.1
Moschen, A.R.2
-
149
-
-
84870067162
-
Activation of peroxisome proliferator-activated receptor d inhibits human macrophage foam cell formation and the inflammatory response induced by very low-density lipoprotein
-
Bojic L, Sawyez C, Telford D, Edwards J, Hegele R, Huff M. Activation of peroxisome proliferator-activated receptor d inhibits human macrophage foam cell formation and the inflammatory response induced by very low-density lipoprotein. Atheroscler. Thromb. Vasc. Biol. 32(12), 2919-2928 (2012).
-
(2012)
Atheroscler. Thromb. Vasc. Biol
, vol.32
, Issue.12
, pp. 2919-2928
-
-
Bojic, L.1
Sawyez, C.2
Telford, D.3
Edwards, J.4
Hegele, R.5
Huff, M.6
-
150
-
-
33746572217
-
Lipid metabolism mediated by adipocyte lipid binding protein (ALBP/aP2) gene expression in human THP-1 macrophages
-
DOI 10.1016/j.atherosclerosis.2005.10.041, PII S0021915005007112
-
Fu Y, Luo L, Luo N, Garvey W. Lipid metabolism mediated by adipocyte lipid binding protein (ALBP/aP2) gene expression in human THP-1 macrophages. Atherosclerosis 188(1), 102-111 (2006). (Pubitemid 44142544)
-
(2006)
Atherosclerosis
, vol.188
, Issue.1
, pp. 102-111
-
-
Fu, Y.1
Luo, L.2
Luo, N.3
Timothy Garvey, W.4
-
151
-
-
83055178179
-
Fatty Acid binding protein 4 is associated with carotid atherosclerosis and outcome in patients with acute ischemic stroke
-
Holm S, Ueland T, Dahl TB et al. Fatty Acid binding protein 4 is associated with carotid atherosclerosis and outcome in patients with acute ischemic stroke. PLoS ONE 6(12), e28785 (2011).
-
(2011)
PLoS ONE
, vol.6
, Issue.12
-
-
Holm, S.1
Ueland, T.2
Dahl, T.B.3
-
152
-
-
84871608927
-
Adipocyte fatty acid binding protein: A novel adipokine involved in the pathogenesis of metabolic and vascular disease?
-
Kralisch S, Fasshauer M. Adipocyte fatty acid binding protein: a novel adipokine involved in the pathogenesis of metabolic and vascular disease? Diabetologia 56(1), 10-21 (2013).
-
(2013)
Diabetologia
, vol.56
, Issue.1
, pp. 10-21
-
-
Kralisch, S.1
Fasshauer, M.2
-
153
-
-
0034959752
-
Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis
-
DOI 10.1038/89076
-
Makowski L, Boord JB, Maeda K et al. Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis. Nat. Med. 7(6), 699-705 (2001). (Pubitemid 32588026)
-
(2001)
Nature Medicine
, vol.7
, Issue.6
, pp. 699-705
-
-
Makowski, L.1
Boord, J.B.2
Maeda, K.3
Babaev, V.R.4
Uysal, K.T.5
Morgan, M.A.6
Parker, R.A.7
Suttles, J.8
Fazio, S.9
Hotamisligil, G.S.10
Linton, M.F.11
-
154
-
-
62449205751
-
A-FABP, a candidate progression marker of human transitional cell carcinoma of the bladder, is differentially regulated by PPAR in urothelial cancer cells
-
Boiteux G, Lascombe I, Roche E et al. A-FABP, a candidate progression marker of human transitional cell carcinoma of the bladder, is differentially regulated by PPAR in urothelial cancer cells. Int. J. Cancer 124(8), 1820-1828 (2009).
-
(2009)
Int. J. Cancer
, vol.124
, Issue.8
, pp. 1820-1828
-
-
Boiteux, G.1
Lascombe, I.2
Roche, E.3
-
155
-
-
0034896267
-
Expression pattern of fatty acid-binding proteins in human normal and cancer prostate cells and tissues
-
Das R, Hammamieh R, Neill R, Melhem M, Jett M. Expression pattern of fatty acid-binding proteins in human normal and cancer prostate cells and tissues. Clin. Cancer Res. 7(6), 1706-1715 (2001). (Pubitemid 32708639)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.6
, pp. 1706-1715
-
-
Das, R.1
Hammamieh, R.2
Neill, R.3
Melhem, M.4
Jett, M.5
-
156
-
-
79960558868
-
Fatty acid binding proteins (FABPs) in prostate, bladder and kidney cancer cell lines and the use of IL-FABP as survival predictor in patients with renal cell carcinoma
-
Tolle A, Suhail S, Jung M, Jung K, Stephan C. Fatty acid binding proteins (FABPs) in prostate, bladder and kidney cancer cell lines and the use of IL-FABP as survival predictor in patients with renal cell carcinoma. BMC Cancer 11, 302 (2011).
-
(2011)
BMC Cancer
, vol.11
, pp. 302
-
-
Tolle, A.1
Suhail, S.2
Jung, M.3
Jung, K.4
Stephan, C.5
-
157
-
-
70350550302
-
Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells
-
Elmasri H, Karaaslan C, Teper Y et al. Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells. FASEB J. 23(11), 3865-3873 (2009).
-
(2009)
FASEB J
, vol.23
, Issue.11
, pp. 3865-3873
-
-
Elmasri, H.1
Karaaslan, C.2
Teper, Y.3
-
158
-
-
84863568692
-
Fatty acid binding protein 4 is expressed in distinct endothelial and non-endothelial cell populations in glioblastoma
-
Cataltepe O, Arikan MC, Ghelfi E et al. Fatty acid binding protein 4 is expressed in distinct endothelial and non-endothelial cell populations in glioblastoma. Neuropathol. Appl. Neurobiol. 38(5), 400-410 (2012).
-
(2012)
Neuropathol. Appl. Neurobiol
, vol.38
, Issue.5
, pp. 400-410
-
-
Cataltepe, O.1
Arikan, M.C.2
Ghelfi, E.3
-
159
-
-
84864073539
-
FABP4 is a candidate marker of cerebellar liponeurocytomas
-
Anghileri E, Eoli M, Paterra R et al. FABP4 is a candidate marker of cerebellar liponeurocytomas. J. Neurooncol. 108(3), 513-519 (2012).
-
(2012)
J. Neurooncol
, vol.108
, Issue.3
, pp. 513-519
-
-
Anghileri, E.1
Eoli, M.2
Paterra, R.3
-
160
-
-
74849087406
-
Adipocyte fatty acid-binding protein as a novel prognostic factor in obese breast cancer patients
-
Hancke K, Grubeck D, Hauser N, Kreienberg R, Weiss J. Adipocyte fatty acid-binding protein as a novel prognostic factor in obese breast cancer patients. Breast Cancer Res. Treat 119(2), 367-367 (2010).
-
(2010)
Breast Cancer Res. Treat
, vol.119
, Issue.2
, pp. 367-367
-
-
Hancke, K.1
Grubeck, D.2
Hauser, N.3
Kreienberg, R.4
Weiss, J.5
-
161
-
-
77949655800
-
Identification of novel PTEN-binding partners: PTEN interaction with fatty acid binding protein FABP4
-
Gorbenko O, Panayotou G, Zhyvoloup A, Volkova D, Gout I, Filonenko V. Identification of novel PTEN-binding partners: PTEN interaction with fatty acid binding protein FABP4. Mol. Cell. Biochem. 337(1-2), 299-305 (2010).
-
(2010)
Mol. Cell. Biochem
, vol.337
, Issue.1-2
, pp. 299-305
-
-
Gorbenko, O.1
Panayotou, G.2
Zhyvoloup, A.3
Volkova, D.4
Gout, I.5
Filonenko, V.6
-
162
-
-
64049092049
-
Induction of gene encoding FABP4 in Pten-null keratinocytes
-
Tsuda M, Inoue-Narita T, Suzuki A, Itami S, Blumenberg M, Manabe M. Induction of gene encoding FABP4 in Pten-null keratinocytes. FEBS Lett. 583(8), 1319-1322 (2009).
-
(2009)
FEBS Lett
, vol.583
, Issue.8
, pp. 1319-1322
-
-
Tsuda, M.1
Inoue-Narita, T.2
Suzuki, A.3
Itami, S.4
Blumenberg, M.5
Manabe, M.6
-
163
-
-
85047694402
-
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
-
DOI 10.1172/JCI200420513
-
Horie Y, Suzuki A, Kataoka E et al. Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas. J. Clin. Invest. 113(12), 1774-1783 (2004). (Pubitemid 39071669)
-
(2004)
Journal of Clinical Investigation
, vol.113
, Issue.12
, pp. 1774-1783
-
-
Horie, Y.1
Suzuki, A.2
Kataoka, E.3
Sasaki, T.4
Hamada, K.5
Sasaki, J.6
Mizuno, K.7
Hasegawa, G.8
Kishimoto, H.9
Iizuka, M.10
Naito, M.11
Enomoto, K.12
Watanabe, S.13
Mak, T.W.14
Nakano, T.15
-
164
-
-
84860217431
-
The functions and regulation of the PTEN tumour suppressor
-
Song MS, Salmena L, Pandolfi PP. The functions and regulation of the PTEN tumour suppressor. Nat. Rev. Mol. Cell Biol. 13(5), 283-296 (2012).
-
(2012)
Nat. Rev. Mol. Cell Biol
, vol.13
, Issue.5
, pp. 283-296
-
-
Song, M.S.1
Salmena, L.2
Pandolfi, P.P.3
-
165
-
-
84877919960
-
PTEN in cancer, metabolism, and aging
-
Ortega-Molina A, Serrano M. PTEN in cancer, metabolism, and aging. Trends Endocrinol. Metab. 24(4), 184-189 (2012).
-
(2012)
Trends Endocrinol. Metab
, vol.24
, Issue.4
, pp. 184-189
-
-
Ortega-Molina, A.1
Serrano, M.2
-
166
-
-
0035815613
-
Tumor Suppressor MMAC/PTEN Inhibits Cytokine-induced NFκB Activation without Interfering with the IκB Degradation Pathway
-
DOI 10.1074/jbc.M007806200
-
Koul D, Yao Y, Abbruzzese JL, Yung WK, Reddy SA. Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway. J. Biol. Chem. 276(14), 11402-11408 (2001). (Pubitemid 38089333)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.14
, pp. 11402-11408
-
-
Koul, D.1
Yao, Y.2
Abbruzzese, J.L.3
Yung, W.K.A.4
Reddy, S.A.G.5
-
167
-
-
34447527440
-
PTEN reduces cuff-induced neointima formation and proinflammatory cytokines
-
DOI 10.1152/ajpheart.01221.2006
-
Koide S, Okazaki M, Tamura M et al. PTEN reduces cuff-induced neointima formation and proinflammatory cytokines. Am. J. Physiol. Heart Circ. Physiol. 292(6), H2824-H2831 (2007). (Pubitemid 47084532)
-
(2007)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.292
, Issue.6
-
-
Koide, S.1
Okazaki, M.2
Tamura, M.3
Ozumi, K.4
Takatsu, H.5
Kamezaki, F.6
Tanimoto, A.7
Tasaki, H.8
Sasaguri, Y.9
Nakashima, Y.10
Otsuji, Y.11
-
168
-
-
79951838008
-
Role of microRNA-214-targeting phosphatase and tensin homolog in advanced glycation end product-induced apoptosis delay in monocytes
-
Li LM, Hou DX, Guo YL et al. Role of microRNA-214-targeting phosphatase and tensin homolog in advanced glycation end product-induced apoptosis delay in monocytes. J. Immunol. 186(4), 2552-2560 (2011).
-
(2011)
J. Immunol
, vol.186
, Issue.4
, pp. 2552-2560
-
-
Li, L.M.1
Hou, D.X.2
Guo, Y.L.3
-
169
-
-
79551654446
-
Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: Report of forty-six patients from an international multicenter series
-
Nigrovic P, Mannion M, Prince F et al. Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: report of forty-six patients from an international multicenter series. Arthritis Rheum. 63(2), 545-555 (2011).
-
(2011)
Arthritis Rheum
, vol.63
, Issue.2
, pp. 545-555
-
-
Nigrovic, P.1
Mannion, M.2
Prince, F.3
-
170
-
-
78650224244
-
Blocking interleukin-1beta in acute and chronic autoinflammatory diseases
-
Dinarello CA. Blocking interleukin-1beta in acute and chronic autoinflammatory diseases. J. Intern. Med. 269(1), 16-28 (2011).
-
(2011)
J. Intern. Med
, vol.269
, Issue.1
, pp. 16-28
-
-
Dinarello, C.A.1
-
171
-
-
84864386088
-
Effects of gevokizumab on glycemia and inflammatory markers in Type 2 diabetes
-
Cavelti-Weder C, Babians-Brunner A, Keller C et al. Effects of gevokizumab on glycemia and inflammatory markers in Type 2 diabetes. Diabetes Care 35(8), 1654-1662 (2012).
-
(2012)
Diabetes Care
, vol.35
, Issue.8
, pp. 1654-1662
-
-
Cavelti-Weder, C.1
Babians-Brunner, A.2
Keller, C.3
-
172
-
-
84858643750
-
Inflammasomes in carcinogenesis and anticancer immune responses
-
Zitvogel L, Kepp O, Galluzzi L, Kroemer G. Inflammasomes in carcinogenesis and anticancer immune responses. Nat. Immunol. 13(4), 343-351 (2012).
-
(2012)
Nat. Immunol
, vol.13
, Issue.4
, pp. 343-351
-
-
Zitvogel, L.1
Kepp, O.2
Galluzzi, L.3
Kroemer, G.4
-
173
-
-
0023950461
-
Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications
-
Brownlee M, Cerami A, Vlassara H. Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications. N. Engl. J. Med. 318(20), 1315-1321 (1988).
-
(1988)
N. Engl. J. Med
, vol.318
, Issue.20
, pp. 1315-1321
-
-
Brownlee, M.1
Cerami, A.2
Vlassara, H.3
-
174
-
-
48249151077
-
Agents that block advanced glycation end product (AGE)-RAGE (receptor for AGEs)-oxidative stress system: A novel therapeutic strategy for diabetic vascular complications
-
Yamagishi S, Nakamura K, Matsui T, Ueda S, Fukami K, Okuda S. Agents that block advanced glycation end product (AGE)-RAGE (receptor for AGEs)-oxidative stress system: a novel therapeutic strategy for diabetic vascular complications. Expert Opin. Investig. Drugs 17(7), 983-996 (2008).
-
(2008)
Expert Opin. Investig. Drugs
, vol.17
, Issue.7
, pp. 983-996
-
-
Yamagishi, S.1
Nakamura, K.2
Matsui, T.3
Ueda, S.4
Fukami, K.5
Okuda, S.6
-
175
-
-
57049100299
-
Orally administered microencapsulated lysozyme downregulates serum AGE and reduces the severity of early-stage diabetic nephropathy
-
Cocchietto M, Zorzin L, Toffoli B et al. Orally administered microencapsulated lysozyme downregulates serum AGE and reduces the severity of early-stage diabetic nephropathy. Diabetes Metab. 34(6 Pt 1), 587-594 (2008).
-
(2008)
Diabetes Metab
, vol.34
, Issue.6 PART 1
, pp. 587-594
-
-
Cocchietto, M.1
Zorzin, L.2
Toffoli, B.3
-
176
-
-
68949098291
-
Phase i clinical studies of the advanced glycation end-product (AGE)-breaker TRC4186: Safety, tolerability and pharmacokinetics in healthy subjects
-
Chandra KP, Shiwalkar A, Kotecha J et al. Phase I clinical studies of the advanced glycation end-product (AGE)-breaker TRC4186: safety, tolerability and pharmacokinetics in healthy subjects. Clin. Drug Investig. 29(9), 559-575 (2009).
-
(2009)
Clin. Drug Investig
, vol.29
, Issue.9
, pp. 559-575
-
-
Chandra, K.P.1
Shiwalkar, A.2
Kotecha, J.3
-
177
-
-
33745741894
-
Soluble receptor for advanced glycation end products: From disease marker to potential therapeutic target
-
Geroldi D, Falcone C, Emanuele E. Soluble receptor for advanced glycation end products: from disease marker to potential therapeutic target. Curr. Med. Chem. 13(17), 1971-1978 (2006).
-
(2006)
Curr. Med. Chem
, vol.13
, Issue.17
, pp. 1971-1978
-
-
Geroldi, D.1
Falcone, C.2
Emanuele, E.3
-
178
-
-
80052258842
-
PF-04494700, an oral inhibitor of receptor for advanced glycation end products (RAGE), in Alzheimer disease
-
Sabbagh MN, Agro A, Bell J, Aisen PS, Schweizer E, Galasko D. PF-04494700, an oral inhibitor of receptor for advanced glycation end products (RAGE), in Alzheimer disease. Alzheimer Dis. Assoc. Disord. 25(3), 206-212 (2011).
-
(2011)
Alzheimer Dis. Assoc. Disord
, vol.25
, Issue.3
, pp. 206-212
-
-
Sabbagh, M.N.1
Agro, A.2
Bell, J.3
Aisen, P.S.4
Schweizer, E.5
Galasko, D.6
-
179
-
-
84873403513
-
An emerging role of glucagon-like Peptide-1 in preventing advanced-glycation-end-product-mediated damages in diabetes
-
Puddu A, Mach F, Nencioni A, Viviani GL, Montecucco F. An emerging role of glucagon-like Peptide-1 in preventing advanced-glycation-end-product-mediated damages in diabetes. Mediators Inflamm. 591056 (2013).
-
(2013)
Mediators Inflamm
, pp. 591056
-
-
Puddu, A.1
MacH, F.2
Nencioni, A.3
Viviani, G.L.4
Montecucco, F.5
-
180
-
-
77951232674
-
Adipocyte fatty acid-binding protein modulates inflammatory responses in macrophages through a positive feedback loop involving c-Jun NH2-terminal kinases and activator protein-1
-
Hui X, Li H, Zhou Z et al. Adipocyte fatty acid-binding protein modulates inflammatory responses in macrophages through a positive feedback loop involving c-Jun NH2-terminal kinases and activator protein-1. J. Biol. Chem. 285(14), 10273-10280 (2010).
-
(2010)
J. Biol. Chem
, vol.285
, Issue.14
, pp. 10273-10280
-
-
Hui, X.1
Li, H.2
Zhou, Z.3
-
181
-
-
79952386370
-
Chronic administration of BMS309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells
-
Lee MY, Li H, Xiao Y, Zhou Z, Xu A, Vanhoutte PM. Chronic administration of BMS309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells. Br. J. Pharmacol. 162(7), 1564-1576 (2011).
-
(2011)
Br. J. Pharmacol
, vol.162
, Issue.7
, pp. 1564-1576
-
-
Lee, M.Y.1
Li, H.2
Xiao, Y.3
Zhou, Z.4
Xu, A.5
Vanhoutte, P.M.6
-
182
-
-
84865640880
-
BMS309403 stimulates glucose uptake in myotubes through activation of AMP-activated protein kinase
-
Lin W, Huang X, Zhang L et al. BMS309403 stimulates glucose uptake in myotubes through activation of AMP-activated protein kinase. PLoS ONE 7(8), e44570 (2012).
-
(2012)
PLoS ONE
, vol.7
, Issue.8
-
-
Lin, W.1
Huang, X.2
Zhang, L.3
-
183
-
-
79953315358
-
Small-molecule inhibitors of FABP4/5 ameliorate dyslipidemia but not insulin resistance in mice with diet-induced obesity
-
Lan H, Cheng C, Kowalski T et al. Small-molecule inhibitors of FABP4/5 ameliorate dyslipidemia but not insulin resistance in mice with diet-induced obesity. J. Lipid Res. 52(4), 646-656 (2011).
-
(2011)
J. Lipid Res
, vol.52
, Issue.4
, pp. 646-656
-
-
Lan, H.1
Cheng, C.2
Kowalski, T.3
-
184
-
-
84860329619
-
Design, synthesis and biological evaluation of thiazole-and indole-based derivatives for the treatment of Type II diabetes
-
Xu Q, Huang L, Liu J et al. Design, synthesis and biological evaluation of thiazole-and indole-based derivatives for the treatment of Type II diabetes. Eur. J. Med. Chem. 52, 70-81 (2012).
-
(2012)
Eur. J. Med. Chem
, vol.52
, pp. 70-81
-
-
Xu, Q.1
Huang, L.2
Liu, J.3
-
185
-
-
84868530905
-
RAGE in tissue homeostasis, repair and regeneration
-
Sorci G, Riuzzi F, Giambanco I, Donato R. RAGE in tissue homeostasis, repair and regeneration. Biochem. Biophys. Acta 1833(1), 101-109 (2012).
-
(2012)
Biochem. Biophys. Acta
, vol.1833
, Issue.1
, pp. 101-109
-
-
Sorci, G.1
Riuzzi, F.2
Giambanco, I.3
Donato, R.4
-
186
-
-
4444237280
-
Obesity and cancer
-
DOI 10.1038/sj.onc.1207751
-
Calle E, Thun M. Obesity and cancer. Oncogene 23, 6365-6378 (2004). (Pubitemid 39265505)
-
(2004)
Oncogene
, vol.23
, Issue.38
, pp. 6365-6378
-
-
Calle, E.E.1
Thun, M.J.2
-
187
-
-
84867350954
-
Obesity, metabolic dysregulation, and cancer: A growing concern and an inflammatory (and microenvironmental) issue
-
Hursting SD, Dunlap SM. Obesity, metabolic dysregulation, and cancer: a growing concern and an inflammatory (and microenvironmental) issue. Ann. NY Acad. Sci. 1271, 82-87 (2012).
-
(2012)
Ann. NY Acad. Sci
, vol.1271
, pp. 82-87
-
-
Hursting, S.D.1
Dunlap, S.M.2
-
188
-
-
58849143927
-
Peroxisome proliferator-activated receptor gamma pathway targeting in carcinogenesis: Implications for chemoprevention
-
Ondrey F. Peroxisome proliferator-activated receptor gamma pathway targeting in carcinogenesis: implications for chemoprevention. Clin. Cancer Res. 15(1), 2-8 (2009).
-
(2009)
Clin. Cancer Res
, vol.15
, Issue.1
, pp. 2-8
-
-
Ondrey, F.1
-
189
-
-
84857922054
-
Interleukin-1beta-regulating antibody XOMA 052 (gevokizumab) in the treatment of acute exacerbations of resistant uveitis of Behcet's disease: An open-label pilot study
-
Gul A, Tugal-Tutkun I, Dinarello CA et al. Interleukin-1beta-regulating antibody XOMA 052 (gevokizumab) in the treatment of acute exacerbations of resistant uveitis of Behcet's disease: an open-label pilot study. Ann. Rheum. Dis. 71(4), 563-566 (2012).
-
(2012)
Ann. Rheum. Dis
, vol.71
, Issue.4
, pp. 563-566
-
-
Gul, A.1
Tugal-Tutkun, I.2
Dinarello, C.A.3
-
190
-
-
56149124859
-
RAGE ligation affects T cell activation and controls T cell differentiation
-
Chen Y, Akirav EM, Chen W et al. RAGE ligation affects T cell activation and controls T cell differentiation. J. Immunol. 181(6), 4272-4278 (2008).
-
(2008)
J. Immunol
, vol.181
, Issue.6
, pp. 4272-4278
-
-
Chen, Y.1
Akirav, E.M.2
Chen, W.3
-
191
-
-
79960561215
-
Atorvastatin exerts its anti-atherosclerotic effects by targeting the receptor for advanced glycation end products
-
Feng B, Xu L, Wang H et al. Atorvastatin exerts its anti-atherosclerotic effects by targeting the receptor for advanced glycation end products. Biochim. Biophys. Acta 1812(9), 1130-1137 (2011).
-
(2011)
Biochim. Biophys. Acta
, vol.1812
, Issue.9
, pp. 1130-1137
-
-
Feng, B.1
Xu, L.2
Wang, H.3
-
192
-
-
84867747170
-
Rosuvastatin improves vascular function of arteriovenous fistula in a diabetic rat model
-
Roan JN, Fang SY, Chang SW et al. Rosuvastatin improves vascular function of arteriovenous fistula in a diabetic rat model. J. Vasc. Surg. 56(5), 1381-1389 (2012).
-
(2012)
J. Vasc. Surg
, vol.56
, Issue.5
, pp. 1381-1389
-
-
Roan, J.N.1
Fang, S.Y.2
Chang, S.W.3
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