Hyperlipidemia stimulates the extracellular release of the nuclear high mobility group box 1 protein

Cell and Tissue Research

Volumn 346, Issue 3, 2011, Pages 361-368

  Haraba, Raluca ^a   Suica, Viorel I ^a   Uyy, Elena ^a   Ivan, Luminita ^a   Antohe, Felicia ^a  

^a INSTITUTE OF CELLULAR BIOLOGY AND PATHOLOGY NICOLAE SIMIONESCU   (Romania)

Author keywords

AKT; Fluvastatin treatment; Hamster; HMGB1; Hyperlipidemia; RAGE

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; FLUINDOSTATIN; HIGH MOBILITY GROUP B1 PROTEIN; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROTIC PLAQUE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR SPACE; GENE EXPRESSION REGULATION; HYPERLIPIDEMIA; IN VIVO STUDY; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; SYRIAN HAMSTER; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ATHEROSCLEROSIS; CELLS, CULTURED; CRICETINAE; GENE EXPRESSION; HMGB1 PROTEIN; HYPERLIPIDEMIAS; MALE; MESOCRICETUS; SIGNAL TRANSDUCTION;

ANIMALIA; CRICETINAE; MESOCRICETUS AURATUS;

EID: 84856722119     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-011-1277-4     Document Type: Article

References (30)

1. Abraham E, Arcaroli J, Carmody A, Wang H, Tracey KJ (2000) HMG-1 as a mediator of acute lung inflammation. J Immunol 165:2950-2954
2. Bianchi ME (2004) Significant (re)location: how to use chromatin and/or abundant proteins as messages of life and death. Trends Cell Biol 14:287-293 (Pubitemid 38798177)
3. Bustin M (1999) Regulation of DNA-dependent activities by the functional motifs of the high-mobility-group chromosomal proteins. Mol Cell Biol 19:5237-5246 (Pubitemid 29339883)
4. Cipollone F, Iezzi A, Fazia M, Zucchelli M, Pini B, Cuccurullo C, De Cesare D, De Blasis G, Muraro R, Bei R, Chiarelli F, Schmidt AM, Cuccurullo F, Mezzetti A (2003) The receptor RAGE as a progression factor amplifying arachidonatedependent inflammatory and proteolytic response in human atherosclerotic plaques: role of glycemic control. Circulation 108:1070-1077 (Pubitemid 37071516)
5. Degryse B, Bonaldi T, Scaffidi P, Müller S, Resnati M, Sanvito F, Arrigoni G, Bianchi ME (2001) The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells. J Cell Biol 152:1197-1206 (Pubitemid 34280177)
6. Dumitriu IE, Baruah P, Valentinis B, Voll RE, Herrmann M, Nawroth PP, Arnold B, Bianchi ME, Manfredi AA, Rovere-Querini P (2005) Release of high mobility group box 1 by dendritic cells controls T cell activation via the receptor for advanced glycation end products. J Immunol 174:7506-7515 (Pubitemid 40806253)
7. Fang WH, Yao YM, Shi ZG, Wu Y, Lu LR, Sheng ZY (2002) The significance of changes in high mobility group-1 protein mRNA expression in rats after thermal injury. Shock 17:329-333
8. Fernández-Hernando C, Yu J, Dávalos A, Prendergast J, Sessa WC (2010) Endothelial-specific overexpression of caveolin-1 accelerates atherosclerosis in apolipoprotein E-deficient mice. Am J Pathol 177:998-1003
9. Fiuza C, Bustin M, Talwar S, Tropea M, Gerstenberger E, Shelhamer JH, Suffredini AF (2003) Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells. Blood 101:2652-2660 (Pubitemid 36857626)
10. Haraba R, Uyy E, Suica VI, Ivan L, Antohe F (2011) Fluvastatin reduces the high mobility group box 1 protein expression in hyperlipidemia. Int J Cardiol 150:105-107
11. Hori O, Brett J, Slattery T, Cao R, Zhang J, Chen JX, Nagashima M, Lundh ER, Vijay S, Nitecki D, Morser J, Stern D, Schmidt AM (1995) The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin: mediation of neurite outgrowth and co-expression of RAGE and amphoterin in the developing nervous system. J Biol Chem 270:25752-25761
12. Huttunen HJ, Fages C, Rauvala H (1999) Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kB require the cytoplasmic domain of the receptor but different downstream signaling pathways. J Biol Chem 274:19919-19924
13. Jasmin JF, Frank PG, Lisanti MP (2005) Caveolin proteins in cardiopulmonary disease and lung cancers. In: Frank PG, Lisanti MP (eds) Caveolae and lipid rafts: roles in signal transduction and the pathogenesis of human disease, vol 36. Advances in molecular and cell biology. Elsevier, Oxford, pp 211-233 (Pubitemid 43693159)
14. Kalinina N, Agrotis A, Antropova Y, DiVitto G, Kanellakis P, Kostolias G, Ilyinskaya O, Tararak E, Bobik A (2004) Increased expression of the DNA-binding cytokine HMGB1 in human atherosclerotic lesions: role of activated macrophages and cytokines. Arterioscler Thromb Vasc Biol 24:2320-2325 (Pubitemid 39658036)
15. Kim JY, Park JS, Strassheim D, Douglas I, Diaz del Valle F, Asehnoune K, Mitra S, Kwak SH, Yamada S, Maruyama I, Ishizaka A, Abraham E (2005) HMGB1 contributes to the development of acute lung injury after hemorrhage. Am J Physiol Lung Cell Mol Physiol 288:L958-L965 (Pubitemid 40547924)
16. Kokkola R, Sundberg E, Ulfgren AK, Palmblad K, Li J, Wang H, Ulloa L, Yang H, Yan XJ, Furie R, Chiorazzi N, Tracey KJ, Andersson U, Harris HE (2002) High mobility group box chromosomal protein-1: a novel proinflammatory mediator in synovitis. Arthritis Rheum 46:2598-2603 (Pubitemid 36118922)
17. Mosevitsky MI, Novitskaya VA, Iogannsen MG, Zabezhinsky MA (1989) Tissue specificity of nucleo-cytoplasmic distribution of HMG1 and HMG2 proteins and their probable functions. Eur J Biochem 185:303-310 (Pubitemid 19276633)
18. Park JS, Svetkauskaite D, He Q, Kim JY, Strassheim D, Ishizaka A, Abraham E (2004) Involvement of Toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem 279:7370-7377 (Pubitemid 38294612)
19. Porto A, Palumbo R, Pieroni M, Aprigliano G, Chiesa R, Sanvito F, Maseri A, Bianchi ME (2006) Smooth muscle cells in human atherosclerotic plaques secrete and proliferate in response to high mobility group box 1 protein. FASEB J 20:2565-2566
20. Rendon-Mitchell B, Ochani M, Li J, Han J, Wang H, Yang H, Susarla S, Czura C, Mitchell RA, Chen G, Sama AE, Tracey KJ, Wang H (2003) IFN-gamma induces high mobility group box 1 protein release partly through a TNF-dependent mechanism. J Immunol 170:3890-3897 (Pubitemid 36361997)
21. Scaffidi P, Misteli T, Bianchi ME (2002) Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 418:191-195 (Pubitemid 34773774)
22. Sun NK, Chao CC (2005) The cytokine activity of HMGB1- extracellular escape of the nuclear protein. Chang Gung Med J 28:673-682 (Pubitemid 41771137)
23. Tang D, Kang R, Xiao W, Wang H, Calderwood SK, Xiao X (2007) The anti-inflammatory effects of heat shock protein 72 involve inhibition of high-mobility-group box 1 release and proinflammatory function in macrophages. J Immunol 179:1236-1244
24. Treutiger CJ, Mullins GE, Johansson AS, Rouhiainen A, Rauvala HM, Erlandsson-Harris H, Andersson U, Yang H, Tracey KJ, Andersson J, Palmblad JE (2003) High mobility group 1 B-box mediates activation of human endothelium. J Intern Med 254:375-385 (Pubitemid 37211261)
25. Tsung A, Sahai R, Tanaka H, Nakao A, Fink MP, Lotze MT, Yang H, Li J, Tracey KJ, Geller DA, Billiar TR (2005) The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemiareperfusion. J Exp Med 201:1135-1143 (Pubitemid 40524681)
26. Uyy E, Antohe F, Ivan L, Haraba R, Radu DL, Simionescu M (2010) Upregulation of caveolin-1 expression is associated with structural modifications of endothelial cells in diabetic lung. Microvasc Res 79:154-159
27. Wang H, Bloom O, Zhang M, Vishnubhakat JM, Ombrellino M, Che J, Frazier A, Yang H, Ivanova S, Borovikova L, Manogue KR, Faist E, Abraham E, Andersson J, Andersson U, Molina PE, Abumrad NN, Sama A, Tracey KJ (1999) HMG-1 as a late mediator of endotoxin lethality in mice. Science 285:248-251 (Pubitemid 29329996)
28. Yan SF, Ramasamy R, Schmidt AM (2009) The receptor for advanced glycation endproducts (RAGE) and cardiovascular disease. Expert Rev Mol Med 11:e9
29. Yang H, Wang H, Czura CJ, Tracey KJ (2005) The cytokine activity of HMGB1. J Leukoc Biol 78:1-8 (Pubitemid 40979937)
30. Yang J, Huang C, Yang J, Jiang H, Ding J (2010) Statins attenuate high mobility group box-1 protein induced vascular endothelial activation: a key role for TLR4/NF-κB signaling pathway. Mol Cell Biochem 345:189-195