메뉴 건너뛰기




Volumn , Issue , 2012, Pages

The complexity of sporadic Alzheimer's disease pathogenesis: The role of RAGE as therapeutic target to promote neuroprotection by inhibiting neurovascular dysfunction

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; AMYLOID BETA PROTEIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HISTONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NEUROPROTECTIVE AGENT; PF 04494700; THIOREDOXIN INTERACTING PROTEIN; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN;

EID: 84859761969     PISSN: None     EISSN: 20900252     Source Type: Journal    
DOI: 10.1155/2012/734956     Document Type: Review
Times cited : (52)

References (103)
  • 1
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • DOI 10.1126/science.1072994
    • Hardy J., Selkoe D. J., The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics Science 2002 297 5580 353 356 (Pubitemid 34790756)
    • (2002) Science , vol.297 , Issue.5580 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 2
    • 69949107465 scopus 로고    scopus 로고
    • The unsolved relationship of brain aging and late-onset Alzheimer disease
    • Kern A., Behl C., The unsolved relationship of brain aging and late-onset Alzheimer disease Biochimica et Biophysica Acta 2009 1790 1124 1232
    • (2009) Biochimica et Biophysica Acta , vol.1790 , pp. 1124-1232
    • Kern, A.1    Behl, C.2
  • 3
    • 67650844275 scopus 로고    scopus 로고
    • Epidemiology of Alzheimer's disease: Occurrence, determinants, and strategies toward intervention
    • Qiu C., Kivipelto M., Von Strauss E., Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention Dialogues in Clinical Neuroscience 2009 11 2 111 128
    • (2009) Dialogues in Clinical Neuroscience , vol.11 , Issue.2 , pp. 111-128
    • Qiu, C.1    Kivipelto, M.2    Von Strauss, E.3
  • 5
    • 72949094439 scopus 로고    scopus 로고
    • Copper and zinc binding to amyloid: Coordination, dynamics, aggregation, reactivity and metal-ion transfer
    • Faller P., Copper and zinc binding to amyloid- : coordination, dynamics, aggregation, reactivity and metal-ion transfer ChemBioChem 2009 10 18 2837 2845
    • (2009) ChemBioChem , vol.10 , Issue.18 , pp. 2837-2845
    • Faller, P.1
  • 6
    • 75649136954 scopus 로고    scopus 로고
    • Copper transfer from Cu-A to human serum albumin inhibits aggregation, radical production and reduces A toxicity
    • Perrone L., Mothes E., Vignes M., Mockel A., Figueroa C., Miquel M. C., Maddelein M. L., Faller P., Copper transfer from Cu-A to human serum albumin inhibits aggregation, radical production and reduces A toxicity ChemBioChem 2010 11 1 110 118
    • (2010) ChemBioChem , vol.11 , Issue.1 , pp. 110-118
    • Perrone, L.1    Mothes, E.2    Vignes, M.3    Mockel, A.4    Figueroa, C.5    Miquel, M.C.6    Maddelein, M.L.7    Faller, P.8
  • 7
    • 38949208262 scopus 로고    scopus 로고
    • Plaque-bearing mice with reduced levels of oligomeric amyloid- assemblies have intact memory function
    • Lesné S., Kotilinek L., Ashe K. H., Plaque-bearing mice with reduced levels of oligomeric amyloid- assemblies have intact memory function Neuroscience 2008 151 3 745 749
    • (2008) Neuroscience , vol.151 , Issue.3 , pp. 745-749
    • Lesné, S.1    Kotilinek, L.2    Ashe, K.H.3
  • 8
    • 44549087765 scopus 로고    scopus 로고
    • Soluble oligomers of the amyloid -protein impair synaptic plasticity and behavior
    • Selkoe D. J., Soluble oligomers of the amyloid -protein impair synaptic plasticity and behavior Behavioural Brain Research 2008 192 1 106 113
    • (2008) Behavioural Brain Research , vol.192 , Issue.1 , pp. 106-113
    • Selkoe, D.J.1
  • 9
    • 67649726071 scopus 로고    scopus 로고
    • The Alzheimer's disease-diabetes angle: Inevitable fate of aging or metabolic imbalance limiting successful aging
    • Bierhaus A., Nawroth P. P., The Alzheimer's disease-diabetes angle: inevitable fate of aging or metabolic imbalance limiting successful aging Journal of Alzheimer's Disease 2009 16 4 673 675
    • (2009) Journal of Alzheimer's Disease , vol.16 , Issue.4 , pp. 673-675
    • Bierhaus, A.1    Nawroth, P.P.2
  • 11
    • 70449732132 scopus 로고    scopus 로고
    • Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus
    • Valente T., Gella A., Fernndez-Busquets X., Unzeta M., Durany N., Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus Neurobiology of Disease 2010 37 1 67 76
    • (2010) Neurobiology of Disease , vol.37 , Issue.1 , pp. 67-76
    • Valente, T.1    Gella, A.2    Fernndez-Busquets, X.3    Unzeta, M.4    Durany, N.5
  • 12
    • 0032029363 scopus 로고    scopus 로고
    • AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept
    • DOI 10.1016/S0008-6363(97)00233-2, PII S0008636397002332
    • Bierhaus A., Hofmann M. A., Ziegler R., Nawroth P. P., AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept Cardiovascular Research 1998 37 3 586 600 (Pubitemid 28231153)
    • (1998) Cardiovascular Research , vol.37 , Issue.3 , pp. 586-600
    • Bierhaus, A.1    Hofmann, M.A.2    Ziegler, R.3    Nawroth, P.P.4
  • 13
    • 79952785518 scopus 로고    scopus 로고
    • Advanced glycation endproducts as gerontotoxins and biomarkers for carbonyl-based degenerative processes in Alzheimer's disease
    • Rahmadi A., Steiner N., Mnch G., Advanced glycation endproducts as gerontotoxins and biomarkers for carbonyl-based degenerative processes in Alzheimer's disease Clinical Chemistry and Laboratory Medicine 2011 49 3 385 391
    • (2011) Clinical Chemistry and Laboratory Medicine , vol.49 , Issue.3 , pp. 385-391
    • Rahmadi, A.1    Steiner, N.2    Mnch, G.3
  • 18
    • 70349859675 scopus 로고    scopus 로고
    • Multiple levels of regulation determine the role of the receptor for AGE (RAGE) as common soil in inflammation, immune responses and diabetes mellitus and its complications
    • Bierhaus A., Nawroth P. P., Multiple levels of regulation determine the role of the receptor for AGE (RAGE) as common soil in inflammation, immune responses and diabetes mellitus and its complications Diabetologia 2009 52 11 2251 2263
    • (2009) Diabetologia , vol.52 , Issue.11 , pp. 2251-2263
    • Bierhaus, A.1    Nawroth, P.P.2
  • 21
    • 67649739088 scopus 로고    scopus 로고
    • RAGE and Alzheimer's disease: A progression factor for amyloid- - Induced cellular perturbation?
    • Shi D. Y., Bierhaus A., Nawroth P. P., Stern D. M., RAGE and Alzheimer's disease: a progression factor for amyloid- -induced cellular perturbation? Journal of Alzheimer's Disease 2009 16 4 833 843
    • (2009) Journal of Alzheimer's Disease , vol.16 , Issue.4 , pp. 833-843
    • Shi, D.Y.1    Bierhaus, A.2    Nawroth, P.P.3    Stern, D.M.4
  • 22
    • 65649105035 scopus 로고    scopus 로고
    • Clearance of amyloid- peptide across the blood-brain barrier: Implication for therapies in Alzheimer's disease
    • Deane R., Bell R. D., Sagare A., Zlokovic B. V., Clearance of amyloid- peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease CNS and Neurological DisordersDrug Targets 2009 8 1 16 30
    • (2009) CNS and Neurological DisordersDrug Targets , vol.8 , Issue.1 , pp. 16-30
    • Deane, R.1    Bell, R.D.2    Sagare, A.3    Zlokovic, B.V.4
  • 24
    • 34147183707 scopus 로고    scopus 로고
    • Role of the blood-brain barrier in the pathogenesis of Alzheimer's disease
    • DOI 10.2174/156720507780362245
    • Deane R., Zlokovic B. V., Role of the blood-brain barrier in the pathogenesis of Alzheimer's disease Current Alzheimer Research 2007 4 2 191 197 (Pubitemid 46562394)
    • (2007) Current Alzheimer Research , vol.4 , Issue.2 , pp. 191-197
    • Deane, R.1    Zlokovic, B.V.2
  • 26
    • 69249226353 scopus 로고    scopus 로고
    • Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions
    • Perrone L., Devi T. S., Hosoya K. I., Terasaki T., Singh L. P., Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions Journal of Cellular Physiology 2009 221 1 262 272
    • (2009) Journal of Cellular Physiology , vol.221 , Issue.1 , pp. 262-272
    • Perrone, L.1    Devi, T.S.2    Hosoya, K.I.3    Terasaki, T.4    Singh, L.P.5
  • 27
    • 78649745764 scopus 로고    scopus 로고
    • RAGE-TXNIP axis is required for S100B-promoted Schwann cell migration, fibronectin expression and cytokine secretion
    • Sbai O., Devi T. S., Melone M. A. B., Feron F., Khrestchatisky M., Singh L. P., Perrone L., RAGE-TXNIP axis is required for S100B-promoted Schwann cell migration, fibronectin expression and cytokine secretion Journal of Cell Science 2010 123 24 4332 4339
    • (2010) Journal of Cell Science , vol.123 , Issue.24 , pp. 4332-4339
    • Sbai, O.1    Devi, T.S.2    Melone, M.A.B.3    Feron, F.4    Khrestchatisky, M.5    Singh, L.P.6    Perrone, L.7
  • 28
    • 39149097844 scopus 로고    scopus 로고
    • Diverse functions of VDUP1 in cell proliferation, differentiation, and diseases
    • Kim S. Y., Suh H. W., Chung J. W., Yoon S. R., Choi I., Diverse functions of VDUP1 in cell proliferation, differentiation, and diseases Cellular molecular immunology 2007 4 5 345 351
    • (2007) Cellular Molecular Immunology , vol.4 , Issue.5 , pp. 345-351
    • Kim, S.Y.1    Suh, H.W.2    Chung, J.W.3    Yoon, S.R.4    Choi, I.5
  • 30
    • 69249226353 scopus 로고    scopus 로고
    • Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions
    • Perrone L., Devi T. S., Hosoya K. I., Terasaki T., Singh L. P., Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions Journal of Cellular Physiology 2010 221 1 262 272
    • (2010) Journal of Cellular Physiology , vol.221 , Issue.1 , pp. 262-272
    • Perrone, L.1    Devi, T.S.2    Hosoya, K.I.3    Terasaki, T.4    Singh, L.P.5
  • 31
    • 14644401702 scopus 로고    scopus 로고
    • Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin-interacting protein in endothelial cells
    • DOI 10.1172/JCI200523001
    • Yamawaki H., Pan S., Lee R. T., Berk B. C., Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin-interacting protein in endothelial cells Journal of Clinical Investigation 2005 115 3 733 738 (Pubitemid 40322249)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.3 , pp. 733-738
    • Yamawaki, H.1    Pan, S.2    Lee, R.T.3    Berk, B.C.4
  • 33
    • 34147173277 scopus 로고    scopus 로고
    • Insulin resistance and Alzheimer's disease pathogenesis: Potential mechanisms and implications for treatment
    • DOI 10.2174/156720507780362137
    • Craft S., Insulin resistance and Alzheimer's disease pathogenesis: potential mechanisms and implications for treatment Current Alzheimer Research 2007 4 2, article 21 147 152 (Pubitemid 46557503)
    • (2007) Current Alzheimer Research , vol.4 , Issue.2 , pp. 147-152
    • Craft, S.1
  • 35
    • 42449159705 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE) mediates neuronal differentiation and neurite outgrowth
    • DOI 10.1002/jnr.21578
    • Wang L., Li S., Jungalwala F. B., Receptor for advanced glycation end products (RAGE) mediates neuronal differentiation and neurite outgrowth Journal of Neuroscience Research 2008 86 6 1254 1266 (Pubitemid 351571900)
    • (2008) Journal of Neuroscience Research , vol.86 , Issue.6 , pp. 1254-1266
    • Wang, L.1    Li, S.2    Jungalwala, F.B.3
  • 37
    • 0031916984 scopus 로고    scopus 로고
    • The free radical theory of aging matures
    • Beckman K. B., Ames B. N., The free radical theory of aging matures Physiological Reviews 1998 78 2 547 581 (Pubitemid 28182903)
    • (1998) Physiological Reviews , vol.78 , Issue.2 , pp. 547-581
    • Beckman, K.B.1    Ames, B.N.2
  • 38
    • 80052505427 scopus 로고    scopus 로고
    • Reactive metabolites and AGE/RAGE-mediated cellular dysfunction affect the aging processa mini-review
    • Fleming T. H., Humpert P. M., Nawroth P. P., Bierhaus A., Reactive metabolites and AGE/RAGE-mediated cellular dysfunction affect the aging processa mini-review Gerontology 2010 57 5
    • (2010) Gerontology , vol.57 , Issue.5
    • Fleming, T.H.1    Humpert, P.M.2    Nawroth, P.P.3    Bierhaus, A.4
  • 39
    • 34548588380 scopus 로고    scopus 로고
    • Redox proteomics identification of oxidatively modified brain proteins in Alzheimer's disease and mild cognitive impairment: Insights into the progression of this dementing disorder
    • The Multifaceted Aspects of Alzheimer's Disease: From Social to Molecular Problems
    • Butterfield D. A., Sultana R., Redox proteomics identification of oxidatively modified brain proteins in Alzheimer's disease and mild cognitive impairment: insights into the progression of this dementing disorder Journal of Alzheimer's Disease 2007 12 1 61 72 (Pubitemid 47396301)
    • (2007) Journal of Alzheimer's Disease , vol.12 , Issue.1 , pp. 61-72
    • Butterfield, D.A.1    Sultana, R.2
  • 41
    • 0035112495 scopus 로고    scopus 로고
    • Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures
    • DOI 10.1016/S0197-4580(00)00235-9, PII S0197458000002359
    • Lovell M. A., Xie C., Markesbery W. R., Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures Neurobiology of Aging 2001 22 2 187 194 (Pubitemid 32162967)
    • (2001) Neurobiology of Aging , vol.22 , Issue.2 , pp. 187-194
    • Lovell, M.A.1    Xie, C.2    Markesbery, W.R.3
  • 42
    • 0031980065 scopus 로고    scopus 로고
    • Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease
    • DOI 10.1016/S0197-4580(98)00009-8, PII S0197458098000098
    • Markesbery W. R., Lovell M. A., Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease Neurobiology of Aging 1998 19 1 33 36 (Pubitemid 28167792)
    • (1998) Neurobiology of Aging , vol.19 , Issue.1 , pp. 33-36
    • Markesbery, W.R.1    Lovell, M.A.2
  • 43
    • 23944524332 scopus 로고    scopus 로고
    • Posttranslational modification of lipoproteins - A fatal attraction in metabolic disease? Commentary on: Hone et al., Alzheimer's disease amyloid-beta peptide modulates apolipoprotein E isoform specific receptor binding
    • Bierhaus A., Nawroth P. P., Posttranslational modification of lipoproteinsa fatal attraction in metabolic disease? Commentary on: Hone et al., Alzheimer's disease amyloid-beta peptide modulates apolipoprotein E isoform specific receptor binding Journal of Alzheimer's Disease 2005 7 4 315 317 (Pubitemid 41206943)
    • (2005) Journal of Alzheimer's Disease , vol.7 , Issue.4 , pp. 315-317
    • Bierhaus, A.1    Nawroth, P.P.2
  • 44
    • 0348136791 scopus 로고    scopus 로고
    • Protecting the genome: Defence against nucleotide glycation and emerging role of glyoxalase I overexpression in multidrug resistance in cancer chemotherapy
    • Thornalley P. J., Protecting the genome: defence against nucleotide glycation and emerging role of glyoxalase I overexpression in multidrug resistance in cancer chemotherapy Biochemical Society Transactions 2003 31 6 1372 1377 (Pubitemid 38030979)
    • (2003) Biochemical Society Transactions , vol.31 , Issue.6 , pp. 1372-1377
    • Thornalley, P.J.1
  • 46
    • 0031577293 scopus 로고    scopus 로고
    • Immunohistochemical localization of advanced glycation end products, pentosidine, and carboxymethyllysine in lipofuscin pigments of Alzheimer's disease and aged neurons
    • DOI 10.1006/bbrc.1997.6944
    • Horie K., Miyata T., Yasuda T., Takeda A., Yasuda Y., Maeda K., Sobue G., Kurokawa K., Immunohistochemical localization of advanced glycation end products, pentosidine, and carboxymethyllysine in lipofuscin pigments of Alzheimer's disease and aged neurons Biochemical and Biophysical Research Communications 1997 236 2 327 332 (Pubitemid 27373293)
    • (1997) Biochemical and Biophysical Research Communications , vol.236 , Issue.2 , pp. 327-332
    • Horie, K.1    Miyata, T.2    Yasuda, T.3    Takeda, A.4    Yasuda, Y.5    Maeda, K.6    Sobue, G.7    Kurokawa, K.8
  • 48
    • 0034746288 scopus 로고    scopus 로고
    • NF- B in neuronal plasticity and neurodegenerative disorders
    • Mattson M. P., Camandola S., NF- B in neuronal plasticity and neurodegenerative disorders Journal of Clinical Investigation 2001 107 3 247 254
    • (2001) Journal of Clinical Investigation , vol.107 , Issue.3 , pp. 247-254
    • Mattson, M.P.1    Camandola, S.2
  • 49
    • 0028851635 scopus 로고
    • The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of RAGE and amphoterin in the developing nervous system
    • Hori O., Brett J., Slattery T., Cao R., Zhang J., Jing Xian Chen, Nagashima M., Lundh E. R., Vijay S., Nitecki D., Morser J., Stern D., Schmidt A. M., The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of RAGE and amphoterin in the developing nervous system Journal of Biological Chemistry 1995 270 43 25752 25761
    • (1995) Journal of Biological Chemistry , vol.270 , Issue.43 , pp. 25752-25761
    • Hori, O.1    Brett, J.2    Slattery, T.3    Cao, R.4    Zhang, J.5    Xian Chen, J.6    Nagashima, M.7    Lundh, E.R.8    Vijay, S.9    Nitecki, D.10    Morser, J.11    Stern, D.12    Schmidt, A.M.13
  • 51
    • 84856590656 scopus 로고    scopus 로고
    • Immunohistochemical localization of receptor for advanced glycation end (RAGE) products in the R6/2 mouse model of Huntington's disease
    • Anzilotti S., Giamp C., Laurenti D., Immunohistochemical localization of receptor for advanced glycation end (RAGE) products in the R6/2 mouse model of Huntington's disease Brain Research Bulletin 2012 87 2-3 350 358
    • (2012) Brain Research Bulletin , vol.87 , Issue.23 , pp. 350-358
    • Anzilotti, S.1    Giamp, C.2    Laurenti, D.3
  • 52
    • 84861192034 scopus 로고    scopus 로고
    • AGEs induce Alzheimer-like tau pathology and memory deficit via RAGE-mediated GSK-3 activation
    • In press
    • Li X.-H., Lv B.-L., Xie J.-Z., Liu J., Zhou X.-W., Wang J.-Z., AGEs induce Alzheimer-like tau pathology and memory deficit via RAGE-mediated GSK-3 activation. Neurobiology of Aging. In press
    • Neurobiology of Aging
    • Li, X.-H.1    Lv, B.-L.2    Xie, J.-Z.3    Liu, J.4    Zhou, X.-W.5    Wang, J.-Z.6
  • 54
    • 68849129707 scopus 로고    scopus 로고
    • RAGE regulates BACE1 and A generation via NFAT1 activation in Alzheimer's disease animal model
    • Cho H. J., Son S. M., Jin S. M., Hong H. S., Shin D. H., Kim S. J., Huh K., Mook-Jung I., RAGE regulates BACE1 and A generation via NFAT1 activation in Alzheimer's disease animal model FASEB Journal 2009 23 8 2639 2649
    • (2009) FASEB Journal , vol.23 , Issue.8 , pp. 2639-2649
    • Cho, H.J.1    Son, S.M.2    Jin, S.M.3    Hong, H.S.4    Shin, D.H.5    Kim, S.J.6    Huh, K.7    Mook-Jung, I.8
  • 57
    • 41549089757 scopus 로고    scopus 로고
    • Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-β-mediated cortical synaptic dysfunction
    • DOI 10.1523/JNEUROSCI.0204-08.2008
    • Origlia N., Righi M., Capsoni S., Cattaneo A., Fang F., Stern D. M., Chen J. X., Schmidt A. M., Arancio O., Shi D. Y., Domenici L., Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid- -mediated cortical synaptic dysfunction Journal of Neuroscience 2008 28 13 3521 3530 (Pubitemid 351469321)
    • (2008) Journal of Neuroscience , vol.28 , Issue.13 , pp. 3521-3530
    • Origlia, N.1    Righi, M.2    Capsoni, S.3    Cattaneo, A.4    Fang, F.5    Stern, D.M.6    Chen, J.X.7    Schmidt, A.M.8    Arancio, O.9    Shi, D.Y.10    Domenici, L.11
  • 61
    • 1542373544 scopus 로고    scopus 로고
    • Differential effects of "Advanced glycation endproducts" and β-amyloid peptide on glucose utilization and ATP levels in the neuronal cell line SH-SY5Y
    • DOI 10.1007/s00702-003-0038-2, Modelling Alzheimers Dementia
    • Kuhla B., Loske C., Garcia De Arriba S., Schinzel R., Huber J., Mnch G., Differential effects of "Advanced glycation endproducts" and -amyloid peptide on glucose utilization and ATP levels in the neuronal cell line SH-SY5Y Journal of Neural Transmission 2004 111 3 427 439 (Pubitemid 38316614)
    • (2004) Journal of Neural Transmission , vol.111 , Issue.3 , pp. 427-439
    • Kuhla, B.1    Loske, C.2    Garcia De Arriba, S.3    Schinzel, R.4    Huber, J.5    Munch, G.6
  • 62
    • 79953327868 scopus 로고    scopus 로고
    • On the in vivo early toxic properties of A 2535 peptide in the rat hippocampus: Involvement of the receptor-for-advanced glycation-end-products and changes in gene expression
    • Cuevas E., Lantz S. M., Tobon-Velasco C., On the in vivo early toxic properties of A 2535 peptide in the rat hippocampus: involvement of the receptor-for-advanced glycation-end-products and changes in gene expression Neurotoxicology and Teratology 2011 33 2 288 296
    • (2011) Neurotoxicology and Teratology , vol.33 , Issue.2 , pp. 288-296
    • Cuevas, E.1    Lantz, S.M.2    Tobon-Velasco, C.3
  • 64
    • 4544367815 scopus 로고    scopus 로고
    • Developmental expression of receptor for advanced glycation end products (RAGE), amphoterin and sulfoglucuronyl (HNK-1) carbohydrate in mouse cerebellum and their role in neurite outgrowth and cell migration
    • DOI 10.1111/j.1471-4159.2004.02609.x
    • Chou D. K. H., Zhang J., Smith F. I., McCaffery P., Jungalwala F. B., Developmental expression of receptor for advanced glycation end products (RAGE), amphoterin and sulfoglucuronyl (HNK-1) carbohydrate in mouse cerebellum and their role in neurite outgrowth and cell migration Journal of Neurochemistry 2004 90 6 1389 1401 (Pubitemid 39223642)
    • (2004) Journal of Neurochemistry , vol.90 , Issue.6 , pp. 1389-1401
    • Chou, D.K.H.1    Zhang, J.2    Smith, F.I.3    McCaffery, P.4    Jungalwala, F.B.5
  • 65
    • 0033538569 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF- B require the cytoplasmic domain of the receptor but different downstream signaling pathways
    • Huttunen H. J., Fages C., Rauvala H., Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF- B require the cytoplasmic domain of the receptor but different downstream signaling pathways Journal of Biological Chemistry 1999 274 28 19919 19924
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.28 , pp. 19919-19924
    • Huttunen, H.J.1    Fages, C.2    Rauvala, H.3
  • 66
    • 0037064124 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE) signaling induces CREB-dependent chromogranin expression during neuronal differentiation
    • DOI 10.1074/jbc.M202515200
    • Huttunen H. J., Kuja-Panula J., Rauvala H., Receptor for advanced glycation end products (RAGE) signaling induces CREB-dependent chromogranin expression during neuronal differentiation Journal of Biological Chemistry 2002 277 41 38635 38646 (Pubitemid 35154724)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.41 , pp. 38635-38646
    • Huttunen, H.J.1    Kuja-Panula, J.2    Rauvala, H.3
  • 67
    • 0034704068 scopus 로고    scopus 로고
    • Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation
    • DOI 10.1074/jbc.M006993200
    • Huttunen H. J., Kuja-Panula J., Sorci G., Agneletti A. L., Donato R., Rauvala H., Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation Journal of Biological Chemistry 2000 275 51 40096 40105 (Pubitemid 32064635)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.51 , pp. 40096-40105
    • Huttunen, H.J.1    Kuja-Panula, J.2    Sorci, G.3    Agneletti, A.L.4    Donato, R.5    Rauvala, H.6
  • 68
    • 0036510623 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products plays a more important role in cellular survival than in neurite outgrowth during retinoic acid-induced differentiation of neuroblastoma cells
    • DOI 10.1074/jbc.M107627200
    • Sajithlal G., Huttunen H., Rauvala H., Mnch G., Receptor for advanced glycation end products plays a more important role in cellular survival than in neurite outgrowth during retinoic acid-induced differentiation of neuroblastoma cells Journal of Biological Chemistry 2002 277 9 6888 6897 (Pubitemid 34953073)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.9 , pp. 6888-6897
    • Sajithlal, G.1    Huttunen, H.2    Rauvala, H.3    Munch, G.4
  • 69
    • 0036320685 scopus 로고    scopus 로고
    • N-glycans on the receptor for advanced glycation end products influence amphoterin binding and neurite outgrowth
    • DOI 10.1046/j.0022-3042.2002.00796.x
    • Srikrishna G., Huttunen H. J., Johansson L., Weigle B., Yamaguchi Y., Rauvala H., Freeze H. H., N-glycans on the receptor for advanced glycation end products influence amphoterin binding and neurite outgrowth Journal of Neurochemistry 2002 80 6 998 1008 (Pubitemid 34809952)
    • (2002) Journal of Neurochemistry , vol.80 , Issue.6 , pp. 998-1008
    • Srikrishna, G.1    Huttunen, H.J.2    Johansson, L.3    Weigle, B.4    Yamaguchi, Y.5    Rauvala, H.6    Freeze, H.H.7
  • 72
    • 77955281765 scopus 로고    scopus 로고
    • Activated astroglia during chronic inflammation in Alzheimer's disease-do they neglect their neurosupportive roles?
    • Fuller S., Steele M., Mnch G., Activated astroglia during chronic inflammation in Alzheimer's disease-do they neglect their neurosupportive roles? Mutation Research 2010 690 1-2 40 49
    • (2010) Mutation Research , vol.690 , Issue.12 , pp. 40-49
    • Fuller, S.1    Steele, M.2    Mnch, G.3
  • 73
    • 13844281550 scopus 로고    scopus 로고
    • How chronic inflammation can affect the brain and support the development of Alzheimer's disease in old age: The role of microglia and astrocytes
    • DOI 10.1111/j.1474-9728.2004.00101.x
    • Blasko I., Stampfer-Kountchev M., Robatscher P., Veerhuis R., Eikelenboom P., Grubeck-Loebenstein B., How chronic inflammation can affect the brain and support the development of Alzheimer's disease in old age: the role of microglia and astrocytes Aging Cell 2004 3 4 169 176 (Pubitemid 40253499)
    • (2004) Aging Cell , vol.3 , Issue.4 , pp. 169-176
    • Blasko, I.1    Stampfer-Kountchev, M.2    Robatscher, P.3    Veerhuis, R.4    Eikelenboom, P.5    Grubeck-Loebenstein, B.6
  • 74
    • 0035038917 scopus 로고    scopus 로고
    • Inflammation and Alzheimer disease: The good, the bad, and the ugly
    • DOI 10.1038/87839
    • Weninger S. C., Yankner B. A., Inflammation and Alzheimer disease: the good, the bad, and the ugly Nature Medicine 2001 7 5 527 528 (Pubitemid 32448307)
    • (2001) Nature Medicine , vol.7 , Issue.5 , pp. 527-528
    • Weninger, S.C.1    Yankner, B.A.2
  • 76
    • 0032720953 scopus 로고    scopus 로고
    • The role of oxidative stress and NF-κB activation in late diabetic complications
    • Mohamed A. K., Bierhaus A., Schiekofer S., Tritschler H., Ziegler R., Nawroth P. P., The role of oxidative stress and NF- B activation in late diabetic complications BioFactors 1999 10 2-3 157 167 (Pubitemid 29533824)
    • (1999) BioFactors , vol.10 , Issue.2-3 , pp. 157-167
    • Mohamed, A.K.1    Bierhaus, A.2    Schiekofer, S.3    Tritschler, H.4    Ziegler, R.5    Nawroth, P.P.6
  • 78
    • 77951647591 scopus 로고    scopus 로고
    • RAGE-dependent signaling in microglia contributes to neuroinflammation, A accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease
    • Fang, Lue L. F., Yan S., Xu H., Luddy J. S., Chen D., Walker D. G., Stern D. M., Yan S., Schmidt A. M., Chen J. X., Yan S. S., RAGE-dependent signaling in microglia contributes to neuroinflammation, A accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease FASEB Journal 2010 24 4 1043 1055
    • (2010) FASEB Journal , vol.24 , Issue.4 , pp. 1043-1055
    • Fang1    Lue, L.F.2    Yan, S.3    Xu, H.4    Luddy, J.S.5    Chen, D.6    Walker, D.G.7    Stern, D.M.8    Yan, S.9    Schmidt, A.M.10    Chen, J.X.11    Yan, S.S.12
  • 79
    • 77956104594 scopus 로고    scopus 로고
    • Microglial receptor for advanced glycation end product-dependent signal pathway drives -amyloid-induced synaptic depression and long-term depression impairment in entorhinal cortex
    • Origlia N., Bonadonna C., Rosellini A., Leznik E., Arancio O., Yan S. S., Domenici L., Microglial receptor for advanced glycation end product-dependent signal pathway drives -amyloid-induced synaptic depression and long-term depression impairment in entorhinal cortex Journal of Neuroscience 2010 30 34 11414 11425
    • (2010) Journal of Neuroscience , vol.30 , Issue.34 , pp. 11414-11425
    • Origlia, N.1    Bonadonna, C.2    Rosellini, A.3    Leznik, E.4    Arancio, O.5    Yan, S.S.6    Domenici, L.7
  • 81
    • 3442894794 scopus 로고    scopus 로고
    • Blood-brain barrier permeability precedes senile plaque formation in an Alzheimer disease model
    • DOI 10.1038/sj.mn.7800212
    • Ujiie M., Dickstein D. L., Carlow D. A., Jefferies W. A., Blood-brain barrier permeability precedes senile plaque formation in an Alzheimer disease model Microcirculation 2003 10 6 463 470 (Pubitemid 39004272)
    • (2003) Microcirculation , vol.10 , Issue.6 , pp. 463-470
    • Ujiie, M.1    Dickstein, D.L.2    Carlow, D.A.3    Jefferies, W.A.4
  • 82
    • 58549098084 scopus 로고    scopus 로고
    • Blood-brain barrier: Ageing and microvascular diseasesystematic review and meta-analysis
    • Farrall A. J., Wardlaw J. M., Blood-brain barrier: ageing and microvascular diseasesystematic review and meta-analysis Neurobiology of Aging 2009 30 3 337 352
    • (2009) Neurobiology of Aging , vol.30 , Issue.3 , pp. 337-352
    • Farrall, A.J.1    Wardlaw, J.M.2
  • 83
    • 77952568975 scopus 로고    scopus 로고
    • The role and therapeutic potential of monocytic cells in Alzheimer's disease
    • Malm T., Koistinaho M., Muona A., Magga J., Koistinaho J., The role and therapeutic potential of monocytic cells in Alzheimer's disease GLIA 2010 58 8 889 900
    • (2010) GLIA , vol.58 , Issue.8 , pp. 889-900
    • Malm, T.1    Koistinaho, M.2    Muona, A.3    Magga, J.4    Koistinaho, J.5
  • 85
    • 33646846157 scopus 로고    scopus 로고
    • Insulin resistance, inflammation, and cognition in Alzheimer's Disease: Lessons for multiple sclerosis
    • DOI 10.1016/j.jns.2005.08.017, PII S0022510X06000955
    • Watson G. S., Craft S., Insulin resistance, inflammation, and cognition in Alzheimer's Disease: lessons for multiple sclerosis Journal of the Neurological Sciences 2006 245 1-2 21 33 (Pubitemid 43775944)
    • (2006) Journal of the Neurological Sciences , vol.245 , Issue.1-2 , pp. 21-33
    • Watson, G.S.1    Craft, S.2
  • 86
    • 70949084806 scopus 로고    scopus 로고
    • Experimental diabetes mellitus exacerbates Tau pathology in a transgenic mouse model of Alzheimer's disease
    • ARTICLE E7917
    • Ke Y. D., Delerue F., Gladbach A., Gtz J., Ittner L. M., Experimental diabetes mellitus exacerbates Tau pathology in a transgenic mouse model of Alzheimer's disease PLoS ONE 2009 4 11, article e7917
    • (2009) PLoS ONE , vol.4 , Issue.11
    • Ke, Y.D.1    Delerue, F.2    Gladbach, A.3    Gtz, J.4    Ittner, L.M.5
  • 87
    • 34447302853 scopus 로고    scopus 로고
    • Hyperglycemia regulates thioredoxin-ROS activity through induction of thioredoxin-interacting protein (TXNIP) in metastatic breast cancer-derived cells MDA-MB-231
    • Turturro F., Friday E., Welbourne T., Hyperglycemia regulates thioredoxin-ROS activity through induction of thioredoxin-interacting protein (TXNIP) in metastatic breast cancer-derived cells MDA-MB-231 BMC Cancer 2007 7, article 96
    • (2007) BMC Cancer , vol.796
    • Turturro, F.1    Friday, E.2    Welbourne, T.3
  • 88
    • 34249699698 scopus 로고    scopus 로고
    • TXNIP links redox circuitry to glucose control
    • DOI 10.1016/j.cmet.2007.05.011, PII S1550413107001386
    • Muoio D. M., TXNIP links redox circuitry to glucose control Cell Metabolism 2007 5 6 412 414 (Pubitemid 46825503)
    • (2007) Cell Metabolism , vol.5 , Issue.6 , pp. 412-414
    • Muoio, D.M.1
  • 90
    • 77953924466 scopus 로고    scopus 로고
    • Dual targeting of the antagonistic pathways mediated by Sirt1 and TXNIP as a putative approach to enhance the efficacy of anti-aging interventions
    • Mousa S. A., Gallati C., Simone T., Dier E., Yalcin M., Dyskin E., Thangirala S., Hanko C., Rebbaa A., Dual targeting of the antagonistic pathways mediated by Sirt1 and TXNIP as a putative approach to enhance the efficacy of anti-aging interventions Aging 2009 1 4 412 424
    • (2009) Aging , vol.1 , Issue.4 , pp. 412-424
    • Mousa, S.A.1    Gallati, C.2    Simone, T.3    Dier, E.4    Yalcin, M.5    Dyskin, E.6    Thangirala, S.7    Hanko, C.8    Rebbaa, A.9
  • 91
    • 79955754604 scopus 로고    scopus 로고
    • Nutrient-sensing hypothalamic TXNIP links nutrient excess to energy imbalance in mice
    • Blouet C., Schwartz G. J., Nutrient-sensing hypothalamic TXNIP links nutrient excess to energy imbalance in mice Journal of Neuroscience 2011 31 16 6019 6027
    • (2011) Journal of Neuroscience , vol.31 , Issue.16 , pp. 6019-6027
    • Blouet, C.1    Schwartz, G.J.2
  • 93
    • 0034806840 scopus 로고    scopus 로고
    • 2+ influx-mediated suppression of vitamin D3 up-regulated protein 1 (VDUP1) mRNA in cerebellar granule neurons undergoing apoptosis
    • DOI 10.1046/j.1471-4159.2001.00505.x
    • Saitoh T., Tanaka S., Koike T., Rapid induction and Ca2+ influx-mediated suppression of vitamin D3 up-regulated protein 1 (VDUP1) mRNA in cerebellar granule neurons undergoing apoptosis Journal of Neurochemistry 2001 78 6 1267 1276 (Pubitemid 32899758)
    • (2001) Journal of Neurochemistry , vol.78 , Issue.6 , pp. 1267-1276
    • Saitoh, T.1    Tanaka, S.2    Koike, T.3
  • 96
    • 33749521100 scopus 로고    scopus 로고
    • Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: Potential factors in amyloid plaque formation
    • DOI 10.1523/JNEUROSCI.1202-06.2006
    • Oakley H., Cole S. L., Logan S., Maus E., Shao P., Craft J., Guillozet-Bongaarts A., Ohno M., Disterhoft J., Van Eldik L., Berry R., Vassar R., Intraneuronal -amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation Journal of Neuroscience 2006 26 40 10129 10140 (Pubitemid 44527407)
    • (2006) Journal of Neuroscience , vol.26 , Issue.40 , pp. 10129-10140
    • Oakley, H.1    Cole, S.L.2    Logan, S.3    Maus, E.4    Shao, P.5    Craft, J.6    Guillozet-Bongaarts, A.7    Ohno, M.8    Disterhoft, J.9    Van Eldik, L.10    Berry, R.11    Vassar, R.12
  • 98
    • 49649090145 scopus 로고    scopus 로고
    • RAGE recycles at the plasma membrane in S100B secretory vesicles and promotes Schwann cells morphological changes
    • Perrone L., Peluso G., Melone M. A. B., RAGE recycles at the plasma membrane in S100B secretory vesicles and promotes Schwann cells morphological changes Journal of Cellular Physiology 2008 217 1 60 71
    • (2008) Journal of Cellular Physiology , vol.217 , Issue.1 , pp. 60-71
    • Perrone, L.1    Peluso, G.2    Melone, M.A.B.3
  • 99
    • 80052882481 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein mediates TRX1 translocation to the plasma membrane in response to tumor necrosis factor: A key mechanism for vascular endothelial growth factor receptor-2 transactivation by reactive oxygen species
    • World C., Spindel O. N., Berk B. C., Thioredoxin-interacting protein mediates TRX1 translocation to the plasma membrane in response to tumor necrosis factor- : a key mechanism for vascular endothelial growth factor receptor-2 transactivation by reactive oxygen species Arteriosclerosis, Thrombosis, and Vascular Biology 2011 31 8 1890 1897
    • (2011) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.31 , Issue.8 , pp. 1890-1897
    • World, C.1    Spindel, O.N.2    Berk, B.C.3
  • 100
    • 80053405714 scopus 로고    scopus 로고
    • Receptor for Advanced Glycation End products (RAGE) prevents endothelial cell membrane resealing and regulates F-actin remodeling in a -catenin-dependent manner
    • Xiong F., Leonov S., Howard A. C., Xiong S., Zhang B., Mei L., McNeil P., Simon S., Xiong W.-C., Receptor for Advanced Glycation End products (RAGE) prevents endothelial cell membrane resealing and regulates F-actin remodeling in a -catenin-dependent manner Journal of Biological Chemistry 2011 286 40 35061 35070
    • (2011) Journal of Biological Chemistry , vol.286 , Issue.40 , pp. 35061-35070
    • Xiong, F.1    Leonov, S.2    Howard, A.C.3    Xiong, S.4    Zhang, B.5    Mei, L.6    McNeil, P.7    Simon, S.8    Xiong, W.-C.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.