Coupling endonucleases with DNA end-processing enzymes to drive gene disruption

Nature Methods

Volumn 9, Issue 10, 2012, Pages 973-975

  Certo, Michael T ^a,b   Gwiazda, Kamila S ^a,b   Kuhar, Ryan ^b   Sather, Blythe ^b   Curinga, Gabrielle ^b   Mandt, Tyler ^b   Brault, Michelle ^b   Lambert, Abigail R ^b   Baxter, Sarah K ^a,b   Jacoby, Kyle ^a,b   Ryu, Byoung Y ^b   Kiem, Hans Peter ^a,c   Gouble, Agnes ^d   Paques, Frederic ^d   Rawlings, David J ^a,b,e   Scharenberg, Andrew M ^a,b,d,e  

^a UNIVERSITY OF WASHINGTON   (United States)

^b SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^c Fred Hutchinson Cancer Research Center   (United States)

^d Arvid Wallgrens Backe 20   (France)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3' REPAIR EXONUCLEASE 2; CHEMOKINE RECEPTOR CCR5; DOUBLE STRANDED DNA; ENDONUCLEASE; EXONUCLEASE; I SCEI ENDONUCLEASE; UNCLASSIFIED DRUG;

ARTICLE; CYTOTOXICITY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; GENE DISRUPTION; GENE EXPRESSION SYSTEM; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANIMALS; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA REPAIR; ENDONUCLEASES; EXODEOXYRIBONUCLEASES; HEK293 CELLS; HUMANS; MICE; PHOSPHOPROTEINS; RECEPTORS, CCR5;

EID: 84867061435     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nmeth.2177     Document Type: Article

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