-
1
-
-
63449086293
-
Impact of allergy and asthma on quality of life and comparison with other diseases
-
Petersen, K.D. Impact of allergy and asthma on quality of life and comparison with other diseases. Drugs Today (Barc) 2008, 44(Suppl. B): 17-8.
-
(2008)
Drugs Today (Barc)
, vol.44
, Issue.SUPPL. B
, pp. 17-18
-
-
Petersen, K.D.1
-
2
-
-
0032445151
-
Inflammatory mediators of asthma: An update
-
Barnes, P.J., Chung, K.F., Page, C.P. Inflammatory mediators of asthma: an update. Pharmacol Rev 1998, 50(4): 515-96. (Pubitemid 29028812)
-
(1998)
Pharmacological Reviews
, vol.50
, Issue.4
, pp. 515-596
-
-
Barnes, P.J.1
Fan Chung, K.2
Page, C.P.3
-
3
-
-
82255167131
-
Asthma: 2015 and beyond
-
Myers, T.R., Tomasio, L. Asthma: 2015 and beyond. Respir Care 2011, 56(9): 1389-407.
-
(2011)
Respir Care
, vol.56
, Issue.9
, pp. 1389-1407
-
-
Myers, T.R.1
Tomasio, L.2
-
4
-
-
0036108564
-
Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase
-
DOI 10.1038/nm0502-473
-
Hafezi-Moghadam, A., Simoncini, T., Yang, Z. et al. Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase. Nat Med 2002, 8(5): 473-9. (Pubitemid 34546749)
-
(2002)
Nature Medicine
, vol.8
, Issue.5
, pp. 473-479
-
-
Hafezi-Moghadam, A.1
Simoncini, T.2
Yang, Z.3
Limbourg, F.P.4
Plumier, J.-C.5
Rebsamen, M.C.6
Hsieh, C.-M.7
Chui, D.-S.8
Thomas, K.L.9
Prorock, A.J.10
Laubach, V.E.11
Moskowitz, M.A.12
French, B.A.13
Ley, K.14
Liao, J.K.15
-
5
-
-
0141507016
-
Dexamethasone enhances interaction of endogenous Annexin 1 with L-selectin and triggers shedding of L-selectin in the monocytic cell line U-937
-
DOI 10.1038/sj.bjp.0705413
-
de Coupade, C., Solito, E., Levine, J.D. Dexamethasone enhances interaction of endogenous annexin 1 with L-selectin and triggers shedding of L-selectin in the monocytic cell line U-937. Br J Pharmacol 2003, 140(1): 133-45. (Pubitemid 37175839)
-
(2003)
British Journal of Pharmacology
, vol.140
, Issue.1
, pp. 133-145
-
-
De Coupade, C.1
Solito, E.2
Levine, J.D.3
-
6
-
-
0034768594
-
Steroid sensitivity of norepinephrine uptake by human bronchial arterial and rabbit aortic smooth muscle cells
-
Horvath, G., Lieb, T., Conner, G.E., Salathe, M., Wanner, A. Steroid sensitivity of norepinephrine uptake by human bronchial arterial and rabbit aortic smooth muscle cells. Am J Respir Cell Mol Biol 2001, 25(4): 500-6. (Pubitemid 33037683)
-
(2001)
American Journal of Respiratory Cell and Molecular Biology
, vol.25
, Issue.4
, pp. 500-506
-
-
Horvath, G.1
Lieb, T.2
Conner, G.E.3
Salathe, M.4
Wanner, A.5
-
7
-
-
0141679439
-
Norepinephrine transport by the extraneuronal monoamine transporter in human bronchial arterial smooth muscle cells
-
Horvath, G., Sutto, Z., Torbati, A., Conner, G.E., Salathe, M., Wanner, A. Norepinephrine transport by the extraneuronal monoamine transporter in human bronchial arterial smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2003, 285(4): L829-37. (Pubitemid 37158829)
-
(2003)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.285
-
-
Horvath, G.1
Sutto, Z.2
Torbati, A.3
Conner, G.E.4
Salathe, M.5
Wanner, A.6
-
8
-
-
75049085673
-
Vasoconstriction after inhalation of budesonide: A study in the isolated and perfused rat lung
-
Ewing, P., Ryrfeldt, A., Sjoberg, C.O., Andersson, P., Edsbacker, S., Gerde, P. Vasoconstriction after inhalation of budesonide: a study in the isolated and perfused rat lung. Pulm Pharmacol Ther 2010, 23(1): 9-14.
-
(2010)
Pulm Pharmacol Ther
, vol.23
, Issue.1
, pp. 9-14
-
-
Ewing, P.1
Ryrfeldt, A.2
Sjoberg, C.O.3
Andersson, P.4
Edsbacker, S.5
Gerde, P.6
-
9
-
-
0141497509
-
How do corticosteroids work in asthma?
-
Barnes, P.J., Adcock, I.M. How do corticosteroids work in asthma? Ann Intern Med 2003, 139(5, Pt. 1): 359-70. (Pubitemid 38124591)
-
(2003)
Annals of Internal Medicine
, vol.139
, Issue.5
, pp. 359-370
-
-
Barnes, P.J.1
Adcock, I.M.2
-
10
-
-
84958107344
-
The effect of a hormone of the adrenal cortex (17-hydroxy-11- dehydrocorticosterone; Compound E) and of pituitary adrenocorticotropic hormone on rheumatoid arthritis
-
Hench, P.S., Kendall, E.C., et al. The effect of a hormone of the adrenal cortex (17-hydroxy-11-dehydrocorticosterone; compound E) and of pituitary adrenocorticotropic hormone on rheumatoid arthritis. Proc Staff Meet Mayo Clin 1949, 24(8): 181-97.
-
(1949)
Proc Staff Meet Mayo Clin
, vol.24
, Issue.8
, pp. 181-197
-
-
Hench, P.S.1
Kendall, E.C.2
-
11
-
-
0031940695
-
Efficacy and safety of inhaled corticosteroids. New developments
-
Barnes, P.J., Pedersen, S., Busse, W.W. Efficacy and safety of inhaled corticosteroids. New developments. Am J Respir Crit Care Med 1998, 157(3, Pt. 2): S1-53.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, Issue.3 PART 2
-
-
Barnes, P.J.1
Pedersen, S.2
Busse, W.W.3
-
12
-
-
33646493002
-
Reducing oral steroids with inhaled steroids: Is that all that can be achieved?
-
Barnes, N.C. Reducing oral steroids with inhaled steroids: is that all that can be achieved? Chest 2006, 129(5): 1124-5.
-
(2006)
Chest
, vol.129
, Issue.5
, pp. 1124-1125
-
-
Barnes, N.C.1
-
13
-
-
0037624566
-
Multidrug resistance 1 gene (P-glycoprotein 170): An important determinant in gastrointestinal disease?
-
DOI 10.1136/gut.52.5.759
-
Ho, G.T., Moodie, F.M., Satsangi, J. Multidrug resistance 1 gene (P-glycoprotein 170): an important determinant in gastrointestinal disease? Gut 2003, 52(5): 759-66. (Pubitemid 36528884)
-
(2003)
Gut
, vol.52
, Issue.5
, pp. 759-766
-
-
Ho, G.-T.1
Moodie, F.M.2
Satsangi, J.3
-
14
-
-
0036242359
-
P-glycoprotein-170 inhibition significantly reduces cortisol and ciclosporin efflux from human intestinal epithelial cells and T lymphocytes
-
DOI 10.1046/j.1365-2036.2002.01238.x
-
Farrell, R.J., Menconi, M.J., Keates, A.C., Kelly, C.P. P-glycoprotein-170 inhibition significantly reduces cortisol and ciclosporin efflux from human intestinal epithelial cells and T lymphocytes. Aliment Pharmacol Ther 2002, 16(5): 1021-31. (Pubitemid 34461774)
-
(2002)
Alimentary Pharmacology and Therapeutics
, vol.16
, Issue.5
, pp. 1021-1031
-
-
Farrell, R.J.1
Menconi, M.J.2
Keates, A.C.3
Kelly, C.P.4
-
15
-
-
0029863130
-
P-glycoprotein expression in circulating blood leukocytes of patients with steroid-resistant asthma
-
Montano, E., Schmitz, M., Blaser, K., Simon, H.U. P-glycoprotein expression in circulating blood leukocytes of patients with steroid-resistant asthma. J Investig Allergol Clin Immunol 1996, 6(1): 14-21. (Pubitemid 26093606)
-
(1996)
Journal of Investigational Allergology and Clinical Immunology
, vol.6
, Issue.1
, pp. 14-21
-
-
Montano, E.1
Schmitz, M.2
Blaser, K.3
Simon, H.-U.4
-
16
-
-
67649814198
-
The antiinflammatory effects of inhaled corticosteroids versus antileukotrienes on the lymphocyte P-glycoprotein (PGP) expression in asthmatic children
-
Kopriva, F., Dzubak, P., Potesil, J., Hajduch, M. The antiinflammatory effects of inhaled corticosteroids versus antileukotrienes on the lymphocyte P-glycoprotein (PGP) expression in asthmatic children. J Asthma 2009, 46(4): 366-70.
-
(2009)
J Asthma
, vol.46
, Issue.4
, pp. 366-370
-
-
Kopriva, F.1
Dzubak, P.2
Potesil, J.3
Hajduch, M.4
-
17
-
-
78651499250
-
P-glycoprotein transporter expression on a549 respiratory epithelial cells is positively correlated with intracellular dexamethasone levels
-
Cohen, J.S., Benton, A.S., Nwachukwu, F., Ozedirne, T., Teach, S.J., Freishtat, R.J. P-glycoprotein transporter expression on a549 respiratory epithelial cells is positively correlated with intracellular dexamethasone levels. J Investig Med 2010, 58(8): 991-4.
-
(2010)
J Investig Med
, vol.58
, Issue.8
, pp. 991-994
-
-
Cohen, J.S.1
Benton, A.S.2
Nwachukwu, F.3
Ozedirne, T.4
Teach, S.J.5
Freishtat, R.J.6
-
18
-
-
0030702823
-
Association of glucocorticoid insensitivity with increased expression of glucocorticoid receptor β
-
DOI 10.1084/jem.186.9.1567
-
Leung, D.Y., Hamid, Q., Vottero, A. et al. Association of glucocorticoid insensitivity with increased expression of glucocorticoid receptor beta. J Exp Med 1997, 186(9): 1567-74. (Pubitemid 27479816)
-
(1997)
Journal of Experimental Medicine
, vol.186
, Issue.9
, pp. 1567-1574
-
-
Leung, D.Y.M.1
Hamid, Q.2
Vottero, A.3
Szefler, S.J.4
Surs, W.5
Minshall, E.6
Chrousos, G.P.7
Klemm, D.J.8
-
19
-
-
0032914288
-
Increased glucocorticoid receptor β in airway cells of glucocorticoid- insensitive asthma
-
Hamid, Q.A., Wenzel, S.E., Hauk, P.J. et al. Increased glucocorticoid receptor beta in airway cells of glucocorticoid-insensitive asthma. Am J Respir Crit Care Med 1999, 159(5, Pt. 1): 1600-4. (Pubitemid 29227876)
-
(1999)
American Journal of Respiratory and Critical Care Medicine
, vol.159
, Issue.5
, pp. 1600-1604
-
-
Hamid, Q.A.1
Wenzel, S.E.2
Hauk, P.J.3
Tsicopoulos, A.4
Wallaert, B.5
Lafitte, J.-J.6
Chrousos, G.P.7
Szefler, S.J.8
Leung, D.Y.M.9
-
20
-
-
0032053218
-
Glucocorticoid receptor phosphorylation: Overview, function and cell cycle-dependence
-
DOI 10.1016/S0960-0760(97)00185-4, PII S0960076097001854
-
Bodwell, J.E., Webster, J.C., Jewell, C.M., Cidlowski, J.A., Hu, J.M., Munck, A. Glucocorticoid receptor phosphorylation: overview, function and cell cycle-dependence. J Steroid Biochem Mol Biol 1998, 65(1-6): 91-9. (Pubitemid 28335594)
-
(1998)
Journal of Steroid Biochemistry and Molecular Biology
, vol.65
, Issue.1-6
, pp. 91-99
-
-
Bodwell, J.E.1
Webster, J.C.2
Jewell, C.M.3
Cidlowski, J.A.4
Hu, J.-M.5
Munck, A.6
-
21
-
-
0030811225
-
Glucocorticoid-resistant asthma: Pathogenesis and clinical implications for management
-
DOI 10.1183/09031936.97.10071640
-
Szefler, S.J., Leung, D.Y. Glucocorticoid-resistant asthma: pathogenesis and clinical implications for management. Eur Respir J 1997, 10(7): 1640-7. (Pubitemid 27311085)
-
(1997)
European Respiratory Journal
, vol.10
, Issue.7
, pp. 1640-1647
-
-
Szefler, S.J.1
Leung, D.Y.M.2
-
22
-
-
0030587138
-
A novel action of IL-13: Induction of diminished monocyte glucocorticoid receptor-binding affinity
-
Spahn, J.D., Szefler, S.J., Surs, W., Doherty, D.E., Nimmagadda, S.R., Leung, D.Y. A novel action of IL-13: induction of diminished monocyte glucocorticoid receptorbinding affinity. J Immunol 1996, 157(6): 2654-9. (Pubitemid 126450482)
-
(1996)
Journal of Immunology
, vol.157
, Issue.6
, pp. 2654-2659
-
-
Spahn, J.D.1
Szefler, S.J.2
Surs, W.3
Doherty, D.E.4
Nimmagadda, S.R.5
Leung, D.Y.M.6
-
23
-
-
0036231010
-
P38 mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: Role in steroid-insensitive asthma
-
DOI 10.1067/mai.2002.122465
-
Irusen, E., Matthews, J.G., Takahashi, A., Barnes, P.J., Chung, K.F., Adcock, I.M. p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma. J Allergy Clin Immunol 2002, 109(4): 649-57. (Pubitemid 34327193)
-
(2002)
Journal of Allergy and Clinical Immunology
, vol.109
, Issue.4
, pp. 649-657
-
-
Irusen, E.1
Matthews, J.G.2
Takahashi, A.3
Barnes, P.J.4
Chung, K.F.5
Adcock, I.M.6
-
24
-
-
3042788350
-
Modulation of glucocorticoid receptor function via phosphorylation
-
DOI 10.1196/annals.1321.007
-
Ismaili, N., Garabedian, M.J. Modulation of glucocorticoid receptor function via phosphorylation. Ann N Y Acad Sci 2004, 1024: 86-101. (Pubitemid 38879595)
-
(2004)
Annals of the New York Academy of Sciences
, vol.1024
, pp. 86-101
-
-
Ismaili, N.1
Garabedian, M.J.2
-
25
-
-
0025935046
-
Glucocorticoid resistance in chronic asthma. Glucocorticoid pharmacokinetics, glucocorticoid receptor characteristics, and inhibition of peripheral blood T cell proliferation by glucocorticoids in vitro
-
Corrigan, C.J., Brown, P.H., Barnes, N.C., Szefler, S.J., Tsai, J.J., Frew, A.J., Kay, A.B. Glucocorticoid resistance in chronic asthma. Glucocorticoid pharmacokinetics, glucocorticoid receptor characteristics, and inhibition of peripheral blood T cell proliferation by glucocorticoids in vitro. Am Rev Respir Dis 1991, 144(5): 1016-25.
-
(1991)
Am Rev Respir Dis
, vol.144
, Issue.5
, pp. 1016-1025
-
-
Corrigan, C.J.1
Brown, P.H.2
Barnes, N.C.3
Szefler, S.J.4
Tsai, J.J.5
Frew, A.J.6
Kay, A.B.7
-
26
-
-
0028881859
-
Abnormal glucocorticoid receptor-activator protein 1 interaction in steroid-resistant asthma
-
Adcock, I.M., Lane, S.J., Brown, C.R., Lee, T.H., Barnes, P.J. Abnormal glucocorticoid receptor-activator protein 1 interaction in steroid-resistant asthma. J Exp Med 1995, 182(6): 1951-8.
-
(1995)
J Exp Med
, vol.182
, Issue.6
, pp. 1951-1958
-
-
Adcock, I.M.1
Lane, S.J.2
Brown, C.R.3
Lee, T.H.4
Barnes, P.J.5
-
27
-
-
45749101311
-
X-ray crystal structure of the novel enhanced-affinity glucocorticoid agonist fluticasone furoate in the glucocorticoid receptor-ligand binding domain
-
DOI 10.1021/jm800279t
-
Biggadike, K., Bledsoe, R.K., Hassell, A.M., Kirk, B.E., McLay, I.M., Shewchuk, L.M., Stewart, E.L. X-ray crystal structure of the novel enhanced-affinity glucocorticoid agonist fluticasone furoate in the glucocorticoid receptor-ligand binding domain. J Med Chem 2008, 51(12): 3349-52. (Pubitemid 351874991)
-
(2008)
Journal of Medicinal Chemistry
, vol.51
, Issue.12
, pp. 3349-3352
-
-
Biggadike, K.1
Bledsoe, R.K.2
Hassell, A.M.3
Kirk, B.E.4
McLay, I.M.5
Shewchuk, L.M.6
Stewart, E.L.7
-
28
-
-
0032982717
-
Ligand-induced differentiation of glucocorticoid receptor (GR) trans-repression and transactivation: Preferential targetting of NF-κB and lack of I-κB involvement
-
DOI 10.1038/sj.bjp.0702613
-
Adcock, I.M., Nasuhara, Y., Stevens, D.A., Barnes, P.J. Ligand-induced differentiation of glucocorticoid receptor (GR) trans-repression and transactivation: preferential targetting of NF-kappaB and lack of I-kappaB involvement. Br J Pharmacol 1999, 127(4): 1003-11. (Pubitemid 29295361)
-
(1999)
British Journal of Pharmacology
, vol.127
, Issue.4
, pp. 1003-1011
-
-
Adcock, I.M.1
Nasuhara, Y.2
Stevens, D.A.3
Barnes, P.J.4
-
29
-
-
84871649139
-
Inhaled corticosteroid and long-acting beta(2)-agonist pharmacological profiles: Effective asthma therapy in practice
-
Tamm, M., Richards, D.H., Beghe, B., Fabbri, L. Inhaled corticosteroid and long-acting beta(2)-agonist pharmacological profiles: effective asthma therapy in practice. Respir Med 2012, 106(Suppl. 1): S9-S19.
-
(2012)
Respir Med
, vol.106
, Issue.SUPPL. 1
-
-
Tamm, M.1
Richards, D.H.2
Beghe, B.3
Fabbri, L.4
-
30
-
-
0031961237
-
Bronchodilators and corticosteroids in the treatment of asthma
-
DOI 10.1358/dot.1998.34.3.485166
-
Vianna, E.O., Martin, R.J. Bronchodilators and corticosteroids in the treatment of asthma. Drugs Today (Barc) 1998, 34(3): 203-23. (Pubitemid 28168443)
-
(1998)
Drugs of Today
, vol.34
, Issue.3
, pp. 203-223
-
-
Vianna, E.O.1
Martin, R.J.2
-
31
-
-
0030048013
-
Interactions of glucocorticoids and beta 2-agonists
-
Adcock, I.M., Stevens, D.A., Barnes, P.J. Interactions of glucocorticoids and beta 2-agonists. Eur Respir J 1996, 9(1): 160-8.
-
(1996)
Eur Respir J
, vol.9
, Issue.1
, pp. 160-168
-
-
Adcock, I.M.1
Stevens, D.A.2
Barnes, P.J.3
-
32
-
-
24944482440
-
Glucocorticoid receptor nuclear translocation in airway cells after inhaled combination therapy
-
DOI 10.1164/rccm.200408-1041OC
-
Usmani, O.S., Ito, K., Maneechotesuwan, K., Ito, M., Johnson, M., Barnes, P.J., Adcock, I.M. Glucocorticoid receptor nuclear translocation in airway cells after inhaled combination therapy. Am J Respir Crit Care Med 2005, 172(6): 704-12. (Pubitemid 41324225)
-
(2005)
American Journal of Respiratory and Critical Care Medicine
, vol.172
, Issue.6
, pp. 704-712
-
-
Usmani, O.S.1
Ito, K.2
Maneechotesuwan, K.3
Ito, M.4
Johnson, M.5
Barnes, P.J.6
Adcock, I.M.7
-
33
-
-
0037975664
-
Possible anti-inflammatory effect of salmeterol against interleukin-8 and neutrophil activation in asthma in vivo
-
Reid, D.W., Ward, C., Wang, N., Zheng, L., Bish, R., Orsida, B., Walters, E.H. Possible anti-inflammatory effect of salmeterol against interleukin-8 and neutrophil activation in asthma in vivo. Eur Respir J 2003, 21(6): 994-9. (Pubitemid 36675616)
-
(2003)
European Respiratory Journal
, vol.21
, Issue.6
, pp. 994-999
-
-
Reid, D.W.1
Ward, C.2
Wang, N.3
Zheng, L.4
Bish, R.5
Orsida, B.6
Walters, E.H.7
-
34
-
-
0036191465
-
Additive anti-inflammatory effect of formoterol and budesonide on human lung fibroblasts
-
DOI 10.1136/thorax.57.3.237
-
Spoelstra, F.M., Postma, D.S., Hovenga, H., Noordhoek, J.A., Kauffman, H.F. Additive anti-inflammatory effect of formoterol and budesonide on human lung fibroblasts. Thorax 2002, 57(3): 237-41. (Pubitemid 34214410)
-
(2002)
Thorax
, vol.57
, Issue.3
, pp. 237-241
-
-
Spoelstra, F.M.1
Postma, D.S.2
Hovenga, H.3
Noordhoek, J.A.4
Kauffman, H.F.5
-
35
-
-
77957768543
-
Tiotropium bromide step-up therapy for adults with uncontrolled asthma
-
Peters, S.P., Kunselman, S.J., Icitovic, N. et al. Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med 2010, 363(18): 1715-26.
-
(2010)
N Engl J Med
, vol.363
, Issue.18
, pp. 1715-1726
-
-
Peters, S.P.1
Kunselman, S.J.2
Icitovic, N.3
-
36
-
-
49649102385
-
Tiotropium bromide is effective for severe asthma with noneosinophilic phenotype
-
Iwamoto, H., Yokoyama, A., Shiota, N., Shoda, H., Haruta, Y., Hattori, N., Kohno, N. Tiotropium bromide is effective for severe asthma with noneosinophilic phenotype. Eur Respir J 2008, 31(6): 1379-80.
-
(2008)
Eur Respir J
, vol.31
, Issue.6
, pp. 1379-1380
-
-
Iwamoto, H.1
Yokoyama, A.2
Shiota, N.3
Shoda, H.4
Haruta, Y.5
Hattori, N.6
Kohno, N.7
-
37
-
-
36349023217
-
Improvements with tiotropium in COPD patients with concomitant asthma
-
DOI 10.1016/j.rmed.2007.08.003, PII S0954611107003587
-
Magnussen, H., Bugnas, B., van Noord, J., Schmidt, P., Gerken, F., Kesten, S. Improvements with tiotropium in COPD patients with concomitant asthma. Respir Med 2008, 102(1): 50-6. (Pubitemid 350151827)
-
(2008)
Respiratory Medicine
, vol.102
, Issue.1
, pp. 50-56
-
-
Magnussen, H.1
Bugnas, B.2
Van Noord, J.3
Schmidt, P.4
Gerken, F.5
Kesten, S.6
-
38
-
-
84863642798
-
Low-dose theophylline restores corticosteroid responsiveness in rats with smoke-induced airway inflammation
-
Sun, X., Li, Q., Gong, Y., Ren, L., Wan, H., Deng, W. Low-dose theophylline restores corticosteroid responsiveness in rats with smoke-induced airway inflammation. Can J Physiol Pharmacol 2012, 90(7): 895-902.
-
(2012)
Can J Physiol Pharmacol
, vol.90
, Issue.7
, pp. 895-902
-
-
Sun, X.1
Li, Q.2
Gong, Y.3
Ren, L.4
Wan, H.5
Deng, W.6
-
39
-
-
84856796629
-
The mechanism of action of doxofylline is unrelated to HDAC inhibition, PDE inhibition or adenosine receptor antagonism
-
van Mastbergen, J., Jolas, T., Allegra, L., Page, C.P. The mechanism of action of doxofylline is unrelated to HDAC inhibition, PDE inhibition or adenosine receptor antagonism. Pulm Pharmacol Ther 2012, 25(1): 55-61.
-
(2012)
Pulm Pharmacol Ther
, vol.25
, Issue.1
, pp. 55-61
-
-
Van Mastbergen, J.1
Jolas, T.2
Allegra, L.3
Page, C.P.4
-
40
-
-
30444451489
-
Roflumilast: A selective phosphodiesterase 4 inhibitor
-
DOI 10.1358/dot.2005.41.10.920428
-
Christie, P. Roflumilast: a selective phosphodiesterase 4 inhibitor. Drugs Today (Barc) 2005, 41(10): 667-75. (Pubitemid 43074776)
-
(2005)
Drugs of Today
, vol.41
, Issue.10
, pp. 667-675
-
-
Christie, P.1
-
41
-
-
84855487820
-
Recent advances in mechanisms and treatments of airway remodeling in asthma: A message from the bench side to the clinic
-
Cho, J.Y. Recent advances in mechanisms and treatments of airway remodeling in asthma: a message from the bench side to the clinic. Korean J Intern Med 2011, 26(4): 367-83.
-
(2011)
Korean J Intern Med
, vol.26
, Issue.4
, pp. 367-383
-
-
Cho, J.Y.1
-
42
-
-
84865588689
-
Omalizumab protects against allergen-induced bronchoconstriction in allergic (immunoglobulin E-mediated) asthma
-
Zielen, S., Lieb, A., De La Motte, S. et al. Omalizumab protects against allergen-induced bronchoconstriction in allergic (immunoglobulin E-mediated) asthma. Int Arch Allergy Immunol 2013, 160(1): 102-10.
-
(2013)
Int Arch Allergy Immunol
, vol.160
, Issue.1
, pp. 102-110
-
-
Zielen, S.1
Lieb, A.2
De La Motte, S.3
-
44
-
-
2642580241
-
Omalizumab: An effective anti-IgE treatment for allergic asthma and rhinitis
-
DOI 10.1358/dot.2004.40.4.820082
-
Casale, T.B. Omalizumab: an effective anti-IgE treatment for allergic asthma and rhinitis. Drugs Today (Barc) 2004, 40(4): 367-76. (Pubitemid 38724779)
-
(2004)
Drugs of Today
, vol.40
, Issue.4
, pp. 367-376
-
-
Casale, T.B.1
-
45
-
-
84866772617
-
Omalizumab: An update on efficacy and safety in moderate-to-severe allergic asthma
-
Chipps, B.E., Figliomeni, M., Spector, S. Omalizumab: an update on efficacy and safety in moderate-to-severe allergic asthma. Allergy Asthma Proc 2012, 33(5): 377-85.
-
(2012)
Allergy Asthma Proc
, vol.33
, Issue.5
, pp. 377-385
-
-
Chipps, B.E.1
Figliomeni, M.2
Spector, S.3
-
46
-
-
84860247083
-
Omalizumab and asthma control in patients with moderate-to-severe allergic asthma: A 6-year pragmatic data review
-
Storms, W., Bowdish, M.S., Farrar, J.R. Omalizumab and asthma control in patients with moderate-to-severe allergic asthma: a 6-year pragmatic data review. Allergy Asthma Proc 2012, 33(2): 172-7.
-
(2012)
Allergy Asthma Proc
, vol.33
, Issue.2
, pp. 172-177
-
-
Storms, W.1
Bowdish, M.S.2
Farrar, J.R.3
-
47
-
-
84858432411
-
Effect of omalizumab as add-on therapy on asthma-related quality of life in severe allergic asthma: A Brazilian study (QUALITX)
-
Rubin, A.S., Souza-Machado, A., Andradre-Lima, M., Ferreira, F., Honda, A., Matozo, T.M. Effect of omalizumab as add-on therapy on asthma-related quality of life in severe allergic asthma: a Brazilian study (QUALITX). J Asthma 2012, 49(3): 288-93.
-
(2012)
J Asthma
, vol.49
, Issue.3
, pp. 288-293
-
-
Rubin, A.S.1
Souza-Machado, A.2
Andradre-Lima, M.3
Ferreira, F.4
Honda, A.5
Matozo, T.M.6
-
48
-
-
84859358781
-
Clinical and pharmacoeconomic aspects of omalizumab: A 4-year followup
-
Menzella, F., Facciolongo, N., Piro, R. et al. Clinical and pharmacoeconomic aspects of omalizumab: a 4-year followup. Ther Adv Respir Dis 2012, 6(2): 87-95.
-
(2012)
Ther Adv Respir Dis
, vol.6
, Issue.2
, pp. 87-95
-
-
Menzella, F.1
Facciolongo, N.2
Piro, R.3
-
49
-
-
84874914555
-
Effects of Omalizumab in Non-Atopic Asthma: Results from a Spanish Multicenter Registry
-
de Llano, L.P., Vennera, M.D., Alvarez, F.J. et al. Effects of Omalizumab in Non-Atopic Asthma: Results from a Spanish Multicenter Registry. J Asthma 2013, 50(3): 296-301.
-
(2013)
J Asthma
, vol.50
, Issue.3
, pp. 296-301
-
-
De Llano, L.P.1
Vennera, M.D.2
Alvarez, F.J.3
-
50
-
-
84863307371
-
The oral corticosteroid-sparing effect of omalizumab in children with severe asthma
-
Brodlie, M., McKean, M.C., Moss, S., Spencer, D.A. The oral corticosteroid-sparing effect of omalizumab in children with severe asthma. Arch Dis Child 2012, 97(7): 604-9.
-
(2012)
Arch Dis Child
, vol.97
, Issue.7
, pp. 604-609
-
-
Brodlie, M.1
McKean, M.C.2
Moss, S.3
Spencer, D.A.4
-
52
-
-
0043175378
-
2 dual receptor antagonist, on asthmatic responses in guinea pigs
-
DOI 10.1159/000071267
-
Yamada, T., Takahashi, Y., Ishizaki, M. et al. Effects of RS-601, a novel leukotriene D(4)/thromboxane A(2) dual receptor antagonist, on asthmatic responses in guinea pigs. Pharmacology 2003, 69(1): 51-8. (Pubitemid 36928724)
-
(2003)
Pharmacology
, vol.69
, Issue.1
, pp. 51-58
-
-
Yamada, T.1
Takahashi, Y.2
Ishizaki, M.3
Musoh, K.4
Ohashi, T.5
Tanaka, H.6
Inagaki, N.7
Nagai, H.8
-
53
-
-
84862862358
-
Montelukast as an add-on therapy to inhaled corti-costeroids in the treatment of severe asthma in elderly patients
-
Bozek, A., Warkocka-Szoltysek, B., Filipowska-Gronska, A., Jarzab, J. Montelukast as an add-on therapy to inhaled corti-costeroids in the treatment of severe asthma in elderly patients. J Asthma 2012, 49(5): 530-4.
-
(2012)
J Asthma
, vol.49
, Issue.5
, pp. 530-534
-
-
Bozek, A.1
Warkocka-Szoltysek, B.2
Filipowska-Gronska, A.3
Jarzab, J.4
-
54
-
-
84863893566
-
The efficacy and tolerability of intravenous montelukast in acute asthma exacerbations in Japanese patients
-
Adachi, M., Taniguchi, H., Tohda, Y., Sano, Y., Ishine, T., Smugar, S.S., Hisada, S. The efficacy and tolerability of intravenous montelukast in acute asthma exacerbations in Japanese patients. J Asthma 2012, 49(6): 649-56.
-
(2012)
J Asthma
, vol.49
, Issue.6
, pp. 649-656
-
-
Adachi, M.1
Taniguchi, H.2
Tohda, Y.3
Sano, Y.4
Ishine, T.5
Smugar, S.S.6
Hisada, S.7
-
55
-
-
84875220579
-
Effect of montelukast for treatment of asthma in cigarette smokers
-
Price, D., Popov, T.A., Bjermer, L. et al. Effect of montelukast for treatment of asthma in cigarette smokers. J Allergy Clin Immunol 2013, 131(3): 763-71.
-
(2013)
J Allergy Clin Immunol
, vol.131
, Issue.3
, pp. 763-771
-
-
Price, D.1
Popov, T.A.2
Bjermer, L.3
-
56
-
-
79957484820
-
The efficacy and tolerability of inhaled montelukast plus inhaled mometasone compared with mometasone alone in patients with chronic asthma
-
Philip, G., Villaran, C., Shah, S.R., Vandormael, K., Smugar, S.S., Reiss, T.F. The efficacy and tolerability of inhaled montelukast plus inhaled mometasone compared with mometasone alone in patients with chronic asthma. J Asthma 2011, 48(5): 495-502.
-
(2011)
J Asthma
, vol.48
, Issue.5
, pp. 495-502
-
-
Philip, G.1
Villaran, C.2
Shah, S.R.3
Vandormael, K.4
Smugar, S.S.5
Reiss, T.F.6
-
57
-
-
0028961338
-
Structure refinement of the glucocorticoid receptor-DNA binding domain from NMR data by relaxation matrix calculations
-
van Tilborg, M.A., Bonvin, A.M., Hard, K. et al. Structure refinement of the glucocorticoid receptor-DNA binding domain from NMR data by relaxation matrix calculations. J Mol Biol 1995, 247(4): 689-700.
-
(1995)
J Mol Biol
, vol.247
, Issue.4
, pp. 689-700
-
-
Van Tilborg, M.A.1
Bonvin, A.M.2
Hard, K.3
-
58
-
-
0027770574
-
Refined solution structure of the glucocorticoid receptor DNA-binding domain
-
DOI 10.1021/bi00212a011
-
Baumann, H., Paulsen, K., Kovacs, H., Berglund, H., Wright, A.P., Gustafsson, J.A., Hard, T. Refined solution structure of the glucocorticoid receptor DNA-binding domain. Biochemistry 1993, 32(49): 13463-71. (Pubitemid 24020220)
-
(1993)
Biochemistry
, vol.32
, Issue.49
, pp. 13463-13471
-
-
Baumann, H.1
Paulsen, K.2
Kovacs, H.3
Berglund, H.4
Wright, A.P.H.5
Gustafsson -, J.A.6
Hard, T.7
-
59
-
-
0036299526
-
Structural analysis of the DNA-binding domain of alternatively spliced steroid receptors
-
DOI 10.1677/joe.0.1730429
-
Wickert, L., Selbig, J. Structural analysis of the DNA-binding domain of alternatively spliced steroid receptors. J Endocrinol 2002, 173(3): 429-36. (Pubitemid 34704714)
-
(2002)
Journal of Endocrinology
, vol.173
, Issue.3
, pp. 429-436
-
-
Wickert, L.1
Selbig, J.2
-
60
-
-
70849121003
-
Design and xray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor
-
Biggadike, K., Bledsoe, R.K., Coe, D.M. et al. Design and xray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor. Proc Natl Acad Sci U S A 2009, 106(43): 18114-9.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.43
, pp. 18114-18119
-
-
Biggadike, K.1
Bledsoe, R.K.2
Coe, D.M.3
-
61
-
-
18444405534
-
Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition
-
DOI 10.1016/S0092-8674(02)00817-6
-
Bledsoe, R.K., Montana, V.G., Stanley, T.B. et al. Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition. Cell 2002, 110(1): 93-105. (Pubitemid 34874609)
-
(2002)
Cell
, vol.110
, Issue.1
, pp. 93-105
-
-
Bledsoe, R.K.1
Montana, V.G.2
Stanley, T.B.3
Delves, C.J.4
Apolito, C.J.5
McKee, D.D.6
Consler, T.G.7
Parks, D.J.8
Stewart, E.L.9
Willson, T.M.10
Lambert, M.H.11
Moore, J.T.12
Pearce, K.H.13
Xu H.Eric14
-
62
-
-
84860877711
-
Deciphering modern glucocorticoid cross-pharmacology using ancestral corticosteroid receptors
-
Kohn, J.A., Deshpande, K., Ortlund, E.A. Deciphering modern glucocorticoid cross-pharmacology using ancestral corticosteroid receptors. J Biol Chem 2012, 287(20): 16267-75.
-
(2012)
J Biol Chem
, vol.287
, Issue.20
, pp. 16267-16275
-
-
Kohn, J.A.1
Deshpande, K.2
Ortlund, E.A.3
-
63
-
-
8844234951
-
The glucocorticoid receptor as target for classic and novel anti-inflammatory therapy
-
DOI 10.2174/1568010042634479
-
Cato, A.C., Schacke, H., Sterry, W., Asadullah, K. The glucocorticoid receptor as target for classic and novel anti-inflammatory therapy. Curr Drug Targets Inflamm Allergy 2004, 3(4): 347-53. (Pubitemid 39534771)
-
(2004)
Current Drug Targets: Inflammation and Allergy
, vol.3
, Issue.4
, pp. 347-353
-
-
Cato, A.C.B.1
Schacke, H.2
Sterry, W.3
Asadullah, K.4
-
64
-
-
34748920671
-
Separating transrepression and transactivation: A distressing divorce for the glucocorticoid receptor?
-
DOI 10.1124/mol.107.038794
-
Newton, R., Holden, N.S. Separating transrepression and transactivation: a distressing divorce for the glucocorticoid receptor? Mol Pharmacol 2007, 72(4): 799-809. (Pubitemid 47481403)
-
(2007)
Molecular Pharmacology
, vol.72
, Issue.4
, pp. 799-809
-
-
Newton, R.1
Holden, N.S.2
-
65
-
-
47249160299
-
Recent developments in the discovery of selective glucocorticoid receptor modulators (SGRMs)
-
DOI 10.2174/156802608784535048
-
Hudson, A.R., Roach, S.L., Higuchi, R.I. Recent developments in the discovery of selective glucocorticoid receptor modulators (SGRMs). Curr Top Med Chem 2008, 8(9): 750-65. (Pubitemid 351982564)
-
(2008)
Current Topics in Medicinal Chemistry
, vol.8
, Issue.9
, pp. 750-765
-
-
Hudson, A.R.1
Roach, S.L.2
Higuchi, R.I.3
-
66
-
-
0347719371
-
Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects
-
DOI 10.1073/pnas.0300372101
-
Schacke, H., Schottelius, A., Docke, W.D. et al. Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects. Proc Natl Acad Sci U S A 2004, 101(1): 227-32. (Pubitemid 38084232)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.1
, pp. 227-232
-
-
Schacke, H.1
Schottelius, A.2
Docke, W.-D.3
Strehlke, P.4
Jaroch, S.5
Schmees, N.6
Rehwinkel, H.7
Hennekes, H.8
Asadullah, K.9
-
67
-
-
44649157015
-
Recent progress in the discovery of novel glucocorticoid receptor modulators
-
DOI 10.2174/156802608783955737
-
Takahashi, H., Razavi, H., Thomson, D. Recent progress in the discovery of novel glucocorticoid receptor modulators. Curr Top Med Chem 2008, 8(6): 521-30. (Pubitemid 351982593)
-
(2008)
Current Topics in Medicinal Chemistry
, vol.8
, Issue.6
, pp. 521-530
-
-
Takahashi, H.1
Razavi, H.2
Thomson, D.3
-
68
-
-
34547531177
-
Non-steroidal glucocorticoid agonists-The discovery of aryl pyrazoles as A-ring mimetics
-
DOI 10.1016/j.bmcl.2007.06.066, PII S0960894X07007603
-
Clackers, M., Coe, D.M., Demaine, D.A. et al. Non-steroidal glucocorticoid agonists: the discovery of aryl pyrazoles as Aring mimetics. Bioorg Med Chem Lett 2007, 17(17): 4737-45. (Pubitemid 47187714)
-
(2007)
Bioorganic and Medicinal Chemistry Letters
, vol.17
, Issue.17
, pp. 4737-4745
-
-
Clackers, M.1
Coe, D.M.2
Demaine, D.A.3
Hardy, G.W.4
Humphreys, D.5
Inglis, G.G.A.6
Johnston, M.J.7
Jones, H.T.8
House, D.9
Loiseau, R.10
Minick, D.J.11
Skone, P.A.12
Uings, I.13
McLay, I.M.14
Macdonald, S.J.F.15
-
69
-
-
57749115803
-
Aryl aminopyrazole benzamides as oral non-steroidal selective glucocorticoid receptor agonists
-
Barnett, H.A., Coe, D.M., Cooper, T.W. et al. Aryl aminopyrazole benzamides as oral non-steroidal selective glucocorticoid receptor agonists. Bioorg Med Chem Lett 2009, 19(1): 158-62.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, Issue.1
, pp. 158-162
-
-
Barnett, H.A.1
Coe, D.M.2
Cooper, T.W.3
-
70
-
-
77955274594
-
Targeting inflammation using selective glucocorticoid receptor modulators
-
De Bosscher, K., Haegeman, G., Elewaut, D. Targeting inflammation using selective glucocorticoid receptor modulators. Curr Opin Pharmacol 2010, 10(4): 497-504.
-
(2010)
Curr Opin Pharmacol
, vol.10
, Issue.4
, pp. 497-504
-
-
De Bosscher, K.1
Haegeman, G.2
Elewaut, D.3
-
71
-
-
0036168394
-
Histone deacetylation inhibits IL4 gene expression in T cells
-
DOI 10.1067/mai.2002.121145
-
Valapour, M., Guo, J., Schroeder, J.T., Keen, J., Cianferoni, A., Casolaro, V., Georas, S.N. Histone deacetylation inhibits IL4 gene expression in T cells. J Allergy Clin Immunol 2002, 109(2): 238-45. (Pubitemid 34158287)
-
(2002)
Journal of Allergy and Clinical Immunology
, vol.109
, Issue.2
, pp. 238-245
-
-
Valapour, M.1
Guo, J.2
Schroeder, J.T.3
Keen, J.4
Cianferoni, A.5
Casolaro, V.6
Georas, S.N.7
-
72
-
-
0037329489
-
Glucocorticoid suppression of nuclear factor-κB: A role for histone modifications
-
Kagoshima, M., Ito, K., Cosio, B., Adcock, I.M. Glucocorticoid suppression of nuclear factor-kappa B: a role for histone modifications. Biochem Soc Trans 2003, 31(Pt. 1): 60-5. (Pubitemid 36241397)
-
(2003)
Biochemical Society Transactions
, vol.31
, Issue.1
, pp. 60-65
-
-
Kagoshima, M.1
Ito, K.2
Cosio, B.3
Adcock, I.M.4
-
73
-
-
20744443470
-
Repression of Interleukin-5 transcription by the glucocorticoid receptor targets GATA3 signaling and involves histone deacetylase recruitment
-
DOI 10.1074/jbc.M503659200
-
Jee, Y.K., Gilmour, J., Kelly, A. et al. Repression of interleukin-5 transcription by the glucocorticoid receptor targets GATA3 signaling and involves histone deacetylase recruitment. J Biol Chem 2005, 280(24): 23243-50. (Pubitemid 40853236)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.24
, pp. 23243-23250
-
-
Jee, Y.-K.1
Gilmour, J.2
Kelly, A.3
Bowen, H.4
Richards, D.5
Soh, C.6
Smith, P.7
Hawrylowicz, C.8
Cousins, D.9
Lee, T.10
Lavender, P.11
-
74
-
-
84872932620
-
Sirtuin 1 activator SRT1720 suppresses inflammation in an ovalbumin-induced mouse model of asthma
-
Ichikawa, T., Hayashi, R., Suzuki, K. et al. Sirtuin 1 activator SRT1720 suppresses inflammation in an ovalbumin-induced mouse model of asthma. Respirology 2013, 18(2): 332-9.
-
(2013)
Respirology
, vol.18
, Issue.2
, pp. 332-339
-
-
Ichikawa, T.1
Hayashi, R.2
Suzuki, K.3
-
75
-
-
36749087548
-
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
-
DOI 10.1038/nature06261, PII NATURE06261
-
Milne, J.C., Lambert, P.D., Schenk, S. et al. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature 2007, 450(7170): 712-6. (Pubitemid 350207685)
-
(2007)
Nature
, vol.450
, Issue.7170
, pp. 712-716
-
-
Milne, J.C.1
Lambert, P.D.2
Schenk, S.3
Carney, D.P.4
Smith, J.J.5
Gagne, D.J.6
Jin, L.7
Boss, O.8
Perni, R.B.9
Vu, C.B.10
Bemis, J.E.11
Xie, R.12
Disch, J.S.13
Ng, P.Y.14
Nunes, J.J.15
Lynch, A.V.16
Yang, H.17
Galonek, H.18
Israelian, K.19
Choy, W.20
Iffland, A.21
Lavu, S.22
Medvedik, O.23
Sinclair, D.A.24
Olefsky, J.M.25
Jirousek, M.R.26
Elliott, P.J.27
Westphal, C.H.28
more..
-
76
-
-
42649146208
-
SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease
-
DOI 10.1164/rccm.200708-1269OC
-
Rajendrasozhan, S., Yang, S.R., Kinnula, V.L., Rahman, I. SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2008, 177(8): 861-70. (Pubitemid 351600664)
-
(2008)
American Journal of Respiratory and Critical Care Medicine
, vol.177
, Issue.8
, pp. 861-870
-
-
Rajendrasozhan, S.1
Yang, S.-R.2
Kinnula, V.L.3
Rahman, I.4
-
77
-
-
4043165678
-
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
-
DOI 10.1126/science.1098014
-
Araki, T., Sasaki, Y., Milbrandt, J. Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 2004, 305(5686): 1010-3. (Pubitemid 39071777)
-
(2004)
Science
, vol.305
, Issue.5686
, pp. 1010-1013
-
-
Araki, T.1
Sasaki, Y.2
Milbrandt, J.3
-
78
-
-
0141445981
-
Mechanical stretch activates nuclear factor-kappaB, activator protein-1, and mitogen-activated protein kinases in lung parenchyma: Implications in asthma
-
DOI 10.1096/fj.02-1148com
-
Kumar, A., Lnu, S., Malya, R., Barron, D., Moore, J., Corry, D.B., Boriek, A.M. Mechanical stretch activates nuclear factor-kappaB, activator protein-1, and mitogen-activated protein kinases in lung parenchyma: implications in asthma. FASEB J 2003, 17(13): 1800-11. (Pubitemid 37214774)
-
(2003)
FASEB Journal
, vol.17
, Issue.13
, pp. 1800-1811
-
-
Kumar, A.1
Lnu, S.2
Malya, R.3
Barron, D.4
Moore, J.5
Corry, D.B.6
Boriek, A.M.7
-
79
-
-
18544406054
-
SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence
-
Underwood, D.C., Osborn, R.R., Kotzer, C.J. et al. SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence. J Pharmacol Exp Ther 2000, 293(1): 281-8. (Pubitemid 30180950)
-
(2000)
Journal of Pharmacology and Experimental Therapeutics
, vol.293
, Issue.1
, pp. 281-288
-
-
Underwood, D.C.1
Osborn, R.R.2
Kotzer, C.J.3
Adams, J.L.4
Lee, J.C.5
Webb, E.F.6
Carpenter, D.C.7
Bochnowicz, S.8
Thomas, H.C.9
Hay, D.W.P.10
Griswold, D.E.11
-
80
-
-
14944350956
-
Inhaled p38α mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice
-
DOI 10.1164/rccm.200408-1006OC
-
Duan, W., Chan, J.H., McKay, K. et al. Inhaled p38alpha mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice. Am J Respir Crit Care Med 2005, 171(6): 571-8. (Pubitemid 40365411)
-
(2005)
American Journal of Respiratory and Critical Care Medicine
, vol.171
, Issue.6
, pp. 571-578
-
-
Duan, W.1
Chan, J.H.P.2
McKay, K.3
Crosby, J.R.4
Hui, H.C.5
Leung, B.P.6
Karras, J.G.7
Wong, W.S.F.8
-
81
-
-
52949154357
-
Therapeutic potential of inhaled p38 mitogen-activated protein kinase inhibitors for inflammatory pulmonary diseases
-
Chopra, P., Kanoje, V., Semwal, A., Ray, A. Therapeutic potential of inhaled p38 mitogen-activated protein kinase inhibitors for inflammatory pulmonary diseases. Expert Opin Investig Drugs 2008, 17(10): 1411-25.
-
(2008)
Expert Opin Investig Drugs
, vol.17
, Issue.10
, pp. 1411-1425
-
-
Chopra, P.1
Kanoje, V.2
Semwal, A.3
Ray, A.4
-
82
-
-
81555218671
-
Design and synthesis of inhaled p38 inhibitors for the treatment of chronic obstructive pulmonary disease
-
Millan, D.S., Bunnage, M.E., Burrows, J.L. et al. Design and synthesis of inhaled p38 inhibitors for the treatment of chronic obstructive pulmonary disease. J Med Chem 2011, 54(22): 7797-814.
-
(2011)
J Med Chem
, vol.54
, Issue.22
, pp. 7797-7814
-
-
Millan, D.S.1
Bunnage, M.E.2
Burrows, J.L.3
-
83
-
-
77249130857
-
A novel CCchemokine receptor 3 antagonist, Ki19003, inhibits airway eosinophilia and subepithelial/peribronchial fibrosis induced by repeated antigen challenge in mice
-
Komai, M., Tanaka, H., Nagao, K. et al. A novel CCchemokine receptor 3 antagonist, Ki19003, inhibits airway eosinophilia and subepithelial/ peribronchial fibrosis induced by repeated antigen challenge in mice. J Pharmacol Sci 2010, 112(2): 203-13.
-
(2010)
J Pharmacol Sci
, vol.112
, Issue.2
, pp. 203-213
-
-
Komai, M.1
Tanaka, H.2
Nagao, K.3
-
84
-
-
56649103896
-
Nafamostat mesilate, a potent serine protease inhibitor, inhibits airway eosinophilic inflammation and airway epithelial remodeling in a murine model of allergic asthma
-
Ishizaki, M., Tanaka, H., Kajiwara, D., Toyohara, T., Wakahara, K., Inagaki, N., Nagai, H. Nafamostat mesilate, a potent serine protease inhibitor, inhibits airway eosinophilic inflammation and airway epithelial remodeling in a murine model of allergic asthma. J Pharmacol Sci 2008, 108(3): 355-63.
-
(2008)
J Pharmacol Sci
, vol.108
, Issue.3
, pp. 355-363
-
-
Ishizaki, M.1
Tanaka, H.2
Kajiwara, D.3
Toyohara, T.4
Wakahara, K.5
Inagaki, N.6
Nagai, H.7
-
86
-
-
77954589298
-
CpG oligodeoxynucleotides as TLR9 agonists: Therapeutic application in allergy and asthma
-
Gupta, G.K., Agrawal, D.K. CpG oligodeoxynucleotides as TLR9 agonists: therapeutic application in allergy and asthma. Bio Drugs 2010, 24(4): 225-35.
-
(2010)
Bio Drugs
, vol.24
, Issue.4
, pp. 225-235
-
-
Gupta, G.K.1
Agrawal, D.K.2
-
87
-
-
49749092026
-
Immunomo-dulatory effects of CpG oligodeoxynucleotides on house dust mite-induced airway inflammation in mice
-
Hirose, I., Tanaka, H., Takahashi, G. et al. Immunomo-dulatory effects of CpG oligodeoxynucleotides on house dust mite-induced airway inflammation in mice. Int Arch Allergy Immunol 2008, 147(1): 6-16.
-
(2008)
Int Arch Allergy Immunol
, vol.147
, Issue.1
, pp. 6-16
-
-
Hirose, I.1
Tanaka, H.2
Takahashi, G.3
-
88
-
-
84862207144
-
Targeting of eosinophils in asthma
-
Molfino, N.A. Targeting of eosinophils in asthma. Expert Opin Biol Ther 2012, 12(7): 807-9.
-
(2012)
Expert Opin Biol Ther
, vol.12
, Issue.7
, pp. 807-809
-
-
Molfino, N.A.1
-
89
-
-
80255132925
-
Anti-interleukin-5 antibody therapy in asthma and allergies
-
Corren, J. Anti-interleukin-5 antibody therapy in asthma and allergies. Curr Opin Allergy Clin Immunol 2011, 11(6): 565-70.
-
(2011)
Curr Opin Allergy Clin Immunol
, vol.11
, Issue.6
, pp. 565-570
-
-
Corren, J.1
-
90
-
-
0034458523
-
Synergistic action of endothelin (ET)-1 on the activation of bronchial fibroblast isolated from normal and asthmatic subjects
-
DOI 10.1046/j.1365-2613.2000.00173.x
-
Dube, J., Chakir, J., Dube, C., Grimard, Y., Laviolette, M., Boulet, L.P. Synergistic action of endothelin (ET)-1 on the activation of bronchial fibroblast isolated from normal and asthmatic subjects. Int J Exp Pathol 2000, 81(6): 429-37. (Pubitemid 32291183)
-
(2000)
International Journal of Experimental Pathology
, vol.81
, Issue.6
, pp. 429-437
-
-
Dube, J.1
Chakir, J.2
Dube, C.3
Grimard, Y.4
Laviolette, M.5
Boulet, L.-P.6
-
91
-
-
47649095643
-
The role of ET(A) and ET(B) receptor antagonists in acute and allergic inflammation in mice
-
Kassuya, C.A., Rogerio, A.P., Calixto, J.B. The role of ET(A) and ET(B) receptor antagonists in acute and allergic inflammation in mice. Peptides 2008, 29(8): 1329-37.
-
(2008)
Peptides
, vol.29
, Issue.8
, pp. 1329-1337
-
-
Kassuya, C.A.1
Rogerio, A.P.2
Calixto, J.B.3
-
92
-
-
84857053637
-
The potential use of tyrosine kinase inhibitors in severe asthma
-
Guntur, V.P., Reinero, C.R. The potential use of tyrosine kinase inhibitors in severe asthma. Curr Opin Allergy Clin Immunol 2012, 12(1): 68-75.
-
(2012)
Curr Opin Allergy Clin Immunol
, vol.12
, Issue.1
, pp. 68-75
-
-
Guntur, V.P.1
Reinero, C.R.2
-
93
-
-
84859416461
-
The tyrosine kinase inhibitor masitinib blunts airway inflammation and improves associated lung mechanics in a feline model of chronic allergic asthma
-
Lee-Fowler, T.M., Guntur, V., Dodam, J., Cohn, L.A., DeClue, A.E., Reinero, C.R. The tyrosine kinase inhibitor masitinib blunts airway inflammation and improves associated lung mechanics in a feline model of chronic allergic asthma. Int Arch Allergy Immunol 2012, 158(4): 369-74.
-
(2012)
Int Arch Allergy Immunol
, vol.158
, Issue.4
, pp. 369-374
-
-
Lee-Fowler, T.M.1
Guntur, V.2
Dodam, J.3
Cohn, L.A.4
Declue, A.E.5
Reinero, C.R.6
-
94
-
-
32644435868
-
Benefits of low weekly doses of methotrexate in steroid-dependent asthmatic patients. A double-blind, randomized, placebo-controlled study
-
DOI 10.1016/j.rmed.2005.07.003, PII S0954611105002714
-
Comet, R., Domingo, C., Larrosa, M., Moron, A., Rue, M., Amengual, M.J., Marin, A. Benefits of low weekly doses of methotrexate in steroid-dependent asthmatic patients. A double-blind, randomized, placebo-controlled study. Respir Med 2006, 100(3): 411-9. (Pubitemid 43239875)
-
(2006)
Respiratory Medicine
, vol.100
, Issue.3
, pp. 411-419
-
-
Comet, R.1
Domingo, C.2
Larrosa, M.3
Moron, A.4
Rue, M.5
Amengual, M.-J.6
Marin, A.7
-
96
-
-
0030071686
-
Double-blind, placebo-controlled study of cyclosporin A as a corticosteroid-sparing agent in corticosteroid-dependent asthma
-
Lock, S.H., Kay, A.B., Barnes, N.C. Double-blind, placebocontrolled study of cyclosporin A as a corticosteroid-sparing agent in corticosteroid-dependent asthma. Am J Respir Crit Care Med 1996, 153(2): 509-14. (Pubitemid 26051322)
-
(1996)
American Journal of Respiratory and Critical Care Medicine
, vol.153
, Issue.2
, pp. 509-514
-
-
Lock, S.H.1
Kay, A.B.2
Barnes, N.C.3
-
97
-
-
0035234865
-
Newer and alternative non-steroidal treatments for asthmatic inflammation
-
Dykewicz, M.S. Newer and alternative non-steroidal treatments for asthmatic inflammation. Allergy Asthma Proc 2001, 22(1): 11-5.
-
(2001)
Allergy Asthma Proc
, vol.22
, Issue.1
, pp. 11-15
-
-
Dykewicz, M.S.1
-
99
-
-
31044447205
-
Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients
-
DOI 10.1172/JCI21759
-
Xystrakis, E., Kusumakar, S., Boswell, S. et al. Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients. J Clin Invest 2006, 116(1): 146-55. (Pubitemid 43121799)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.1
, pp. 146-155
-
-
Xystrakis, E.1
Kusumakar, S.2
Boswell, S.3
Peek, E.4
Urry, Z.5
Richards, D.F.6
Adikibi, T.7
Pridgeon, C.8
Dallman, M.9
Loke, T.-K.10
Robinson, D.S.11
Barrat, F.J.12
O'Garra, A.13
Lavender, P.14
Lee, T.H.15
Corrigan, C.16
Hawrylowicz, C.M.17
-
100
-
-
84864499757
-
Oral Nigella sativa oil ameliorates ovalbumin-induced bronchial asthma in mice
-
Balaha, M.F., Tanaka, H., Yamashita, H., Abdel Rahman, M.N., Inagaki, N. Oral Nigella sativa oil ameliorates ovalbumin-induced bronchial asthma in mice. Int Immunopharmacol 2012, 14(2): 224-31.
-
(2012)
Int Immunopharmacol
, vol.14
, Issue.2
, pp. 224-231
-
-
Balaha, M.F.1
Tanaka, H.2
Yamashita, H.3
Abdel Rahman, M.N.4
Inagaki, N.5
-
101
-
-
0026672435
-
Caffeine intake and asthma symptoms
-
Schwartz, J., Weiss, S.T. Caffeine intake and asthma symptoms. Ann Epidemiol 1992, 2(5): 627-35.
-
(1992)
Ann Epidemiol
, vol.2
, Issue.5
, pp. 627-635
-
-
Schwartz, J.1
Weiss, S.T.2
-
102
-
-
84878733811
-
Oral curcumin supplementation in patients with atopic asthma
-
Kim, D.H., Phillips, J.F., Lockey, R.F. Oral curcumin supplementation in patients with atopic asthma. Allergy Rhinol (Providence) 2011, 2(2): e51-3.
-
(2011)
Allergy Rhinol (Providence)
, vol.2
, Issue.2
-
-
Kim, D.H.1
Phillips, J.F.2
Lockey, R.F.3
-
103
-
-
0023513061
-
Effect of BN 52063, a specific PAF-acether antagonist, on bronchial provocation test to allergens in asthmatic patients. A preliminary study
-
DOI 10.1016/0090-6980(87)90295-4
-
Guinot, P., Brambilla, C., Duchier, J., Braquet, P., Bonvoisin, B., Cournot, A. Effect of BN 52063, a specific PAF-acether antagonist, on bronchial provocation test to allergens in asthmatic patients. A preliminary study. Prostaglandins 1987, 34(5): 723-31. (Pubitemid 18010598)
-
(1987)
Prostaglandins
, vol.34
, Issue.5
, pp. 723-731
-
-
Guinot, P.1
Brambilla, C.2
Duchier, J.3
Braquet, P.4
Bonvoisin, B.5
Cournot, A.6
-
104
-
-
0037360854
-
Efficacy of dry extract of ivy leaves in children with bronchial asthma - A review of randomized controlled trials
-
DOI 10.1078/094471103321659979
-
Hofmann, D., Hecker, M., Volp, A. Efficacy of dry extract of ivy leaves in children with bronchial asthma-a review of randomized controlled trials. Phytomedicine 2003, 10(2-3): 213-20. (Pubitemid 36433221)
-
(2003)
Phytomedicine
, vol.10
, Issue.2-3
, pp. 213-220
-
-
Hofmann, D.1
Hecker, M.2
Volp, A.3
-
105
-
-
34250372588
-
In vitro and in vivo antiallergic effects of Glycyrrhiza glabra and its components
-
DOI 10.1055/s-2007-967126
-
Shin, Y.W., Bae, E.A., Lee, B., Lee, S.H., Kim, J.A., Kim, Y.S., Kim, D.H. In vitro and in vivo antiallergic effects of Glycyrrhiza glabra and its components. Planta Medica 2007, 73(3): 257-61. (Pubitemid 46917478)
-
(2007)
Planta Medica
, vol.73
, Issue.3
, pp. 257-261
-
-
Shin, Y.-W.1
Bae, E.-A.2
Lee, B.3
Seung, H.L.4
Jeong, A.K.5
Kim, Y.-S.6
Kim, D.-H.7
-
106
-
-
79959512168
-
The history of Ephedra (ma-huang)
-
Lee, M.R. The history of Ephedra (ma-huang). J R Coll Physicians Edinb 2011, 41(1): 78-84.
-
(2011)
J R Coll Physicians Edinb
, vol.41
, Issue.1
, pp. 78-84
-
-
Lee, M.R.1
-
107
-
-
84864499757
-
Oral Nigella sativa oil ameliorates ovalbumin-induced bronchial asthma in mice
-
Balaha, M.F., Tanaka, H., Yamashita, H., Abdel Rahman, M.N., Inagaki, N. Oral Nigella sativa oil ameliorates ovalbumin-induced bronchial asthma in mice. Agents Actions 2012, 14(2): 224-31.
-
(2012)
Agents Actions
, vol.14
, Issue.2
, pp. 224-231
-
-
Balaha, M.F.1
Tanaka, H.2
Yamashita, H.3
Abdel Rahman, M.N.4
Inagaki, N.5
-
109
-
-
79958117676
-
Panax ginseng ameliorates airway inflammation in an ovalbumin-sensitized mouse allergic asthma model
-
Kim, D.Y., Yang, W.M. Panax ginseng ameliorates airway inflammation in an ovalbumin-sensitized mouse allergic asthma model. J Ethnopharmacol 2011, 136(1): 230-5.
-
(2011)
J Ethnopharmacol
, vol.136
, Issue.1
, pp. 230-235
-
-
Kim, D.Y.1
Yang, W.M.2
-
110
-
-
0030927939
-
The Chinese herbal medicine, Shinpi-To, inhibits IgE-mediated leukotriene synthesis in rat basophilic leukemia-2H3 cells
-
DOI 10.1016/S0378-8741(97)01520-1, PII S0378874197015201
-
Hamasaki, Y., Kobayashi, I., Hayasaki, R. et al. The Chinese herbal medicine, shinpi-to, inhibits IgE-mediated leukotriene synthesis in rat basophilic leukemia-2H3 cells. Indian J Med Res 1997, 56(2): 123-31. (Pubitemid 27217640)
-
(1997)
Journal of Ethnopharmacology
, vol.56
, Issue.2
, pp. 123-131
-
-
Hamasaki, Y.1
Kobayashi, I.2
Hayasaki, R.3
Zaitu, M.4
Muro, E.5
Yamamoto, S.6
Ichimaru, T.7
Miyazaki, S.8
-
111
-
-
0018776789
-
Tylophora indica in bronchial asthma: A double blind study
-
Gupta, S., George, P., Gupta, V., Tandon, V.R., Sundaram, K.R. Tylophora indica in bronchial asthma-a double blind study. Med J Aust 1979, 69: 981-9. (Pubitemid 9239262)
-
(1979)
Indian Journal of Medical Research
, vol.69
, Issue.6
, pp. 981-989
-
-
Gupta, S.1
George, P.2
Gupta, V.3
-
112
-
-
0030031722
-
Consumption of oily fish and childhood asthma risk
-
Hodge, L., Salome, C.M., Peat, J.K., Haby, M.M., Xuan, W., Woolcock, A.J. Consumption of oily fish and childhood asthma risk. Eur Respir J 1996, 164(3): 137-40. (Pubitemid 26051104)
-
(1996)
Medical Journal of Australia
, vol.164
, Issue.3
, pp. 137-140
-
-
Hodge, L.1
Salome, C.M.2
Peat, J.K.3
Haby, M.M.4
Xuan, W.5
Woolcock, A.J.6
-
113
-
-
0030683946
-
Investigation of the effect of short-term change in dietary magnesium intake in asthma
-
DOI 10.1183/09031936.97.10102225
-
Hill, J., Micklewright, A., Lewis, S., Britton, J. Investigation of the effect of short-term change in dietary magnesium intake in asthma. Clin Exp Allergy 1997, 10(10): 2225-9. (Pubitemid 27479540)
-
(1997)
European Respiratory Journal
, vol.10
, Issue.10
, pp. 2225-2229
-
-
Hill, J.1
Micklewright, A.2
Lewis, S.3
Britton, J.4
-
114
-
-
84858307071
-
Asthma in children and nutritional selenium get another look
-
Hoffmann, P.R. Asthma in children and nutritional selenium get another look. Ann N Y Acad Sci 2012, 42(4): 488-9.
-
(2012)
Ann N y Acad Sci
, vol.42
, Issue.4
, pp. 488-489
-
-
Hoffmann, P.R.1
-
115
-
-
0025196164
-
6 metabolism, asthma, and theophylline therapy
-
DOI 10.1111/j.1749-6632.1990.tb28061.x
-
Ubbink, J.B., Vermaak, W.J., Delport, R., Serfontein, W.J., Bartel, P. The relationship between vitamin B6 metabolism, asthma, and theophylline therapy. Acta Med Iran 1990, 585: 285-94. (Pubitemid 20175905)
-
(1990)
Annals of the New York Academy of Sciences
, vol.585
, pp. 285-294
-
-
Ubbink, J.B.1
Vermaak, W.J.H.2
Delport, R.3
Serfontein, W.J.4
Bartel, P.5
-
116
-
-
84864264064
-
-
Nadi, E., Tavakoli, F., Zeraati, F., Goodarzi, M.T., Hashemi, S.H. Effect of vitamin C administration on leukocyte vitamin C level and severity of bronchial asthma. 2012, 50(4): 233-8.
-
(2012)
Effect of Vitamin C Administration on Leukocyte Vitamin C Level and Severity of Bronchial Asthma
, vol.50
, Issue.4
, pp. 233-238
-
-
Nadi, E.1
Tavakoli, F.2
Zeraati, F.3
Goodarzi, M.T.4
Hashemi, S.H.5
|