The tyrosine kinase inhibitor masitinib blunts airway inflammation and improves associated lung mechanics in a feline model of chronic allergic asthma

International Archives of Allergy and Immunology

Volumn 158, Issue 4, 2012, Pages 369-374

  Lee Fowler, Tekla M ^a   Guntur, Vamsi ^b   Dodam, John ^a   Cohn, Leah A ^a   Declue, Amy E ^a   Reinero, Carol R ^a,c  

^a Analytical and Toxicological Services   (United States)

^b University of Missouri   (United States)

^c UNIVERSITY OF MISSOURI   (United States)

Author keywords

Aeroallergens; Airway eosinophilia; Airway hyperresponsiveness; Asthma model; C KIT; IgE

Indexed keywords

ALANINE AMINOTRANSFERASE; ALLERGEN; IMMUNOGLOBULIN E; MASITINIB; METHACHOLINE; PLACEBO;

AIRWAY RESISTANCE; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALLERGIC ASTHMA; ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BERMUDA; BREATH HOLDING; CONTROLLED STUDY; DIARRHEA; DRUG SAFETY; EDEMA; EOSINOPHILIA; HYPERCHOLESTEROLEMIA; HYPOALBUMINEMIA; LUNG COMPLIANCE; LUNG LAVAGE; LUNG MECHANICS; MALE; NEUTROPENIA; NONHUMAN; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RESPIRATORY SYSTEM; RESPIRATORY TRACT INFLAMMATION; THROMBOCYTOPENIA; VENTILATOR;

ALLERGENS; ANIMALS; ANTI-ASTHMATIC AGENTS; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; CATS; CHRONIC DISEASE; CYNODON; EOSINOPHILS; IMMUNOGLOBULIN E; INFLAMMATION; LUNG; MALE; METHACHOLINE CHLORIDE; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES; THIAZOLES;

EID: 84859416461     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000335122     Document Type: Article

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