Effects of RS-601, a novel leukotriene D4/thromboxane A2 dual receptor antagonist, on asthmatic responses in guinea pigs

Pharmacology

Volumn 69, Issue 1, 2003, Pages 51-58

  Yamada, Takatoshi ^a   Takahashi, Yoshimasa ^a   Ishizaki, Masayuki ^a   Musoh, Keiichi ^b   Ohashi, Tetsuo ^b   Tanaka, Hiroyuki ^a   Inagaki, Naoki ^a   Nagai, Hiroichi ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b Abbott Japan Co Ltd   (Japan)

Author keywords

Airway hyperresponsiveness; Bronchial asthma; Leukotriene D4; RS 601; Thromboxane A2

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 4 [4 [5,5,6,6,6 PENTAFLUORO 1 (4 FLUOROBENZENESULFONAMIDO)HEXYL]PHENYL]BUTYRIC ACID; ANTIASTHMATIC AGENT; ANTIGEN; BACTERIUM LIPOPOLYSACCHARIDE; DOMITROBAN; HISTAMINE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; PRANLUKAST; RS 601; UNCLASSIFIED DRUG;

AIRWAY RESISTANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; GUINEA PIG; INFLAMMATORY CELL; MALE; NONHUMAN; PRIORITY JOURNAL;

AIRWAY RESISTANCE; ANIMALS; ANTI-ASTHMATIC AGENTS; ASTHMA; BRONCHIAL HYPERREACTIVITY; BRONCHIAL PROVOCATION TESTS; BUTYRIC ACIDS; DISEASE MODELS, ANIMAL; GUINEA PIGS; LEUKOTRIENE ANTAGONISTS; LIPOPOLYSACCHARIDES; MALE; MEMBRANE PROTEINS; RECEPTORS, LEUKOTRIENE; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; RESPIRATION; SULFONAMIDES;

EID: 0043175378     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000071267     Document Type: Article

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