Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients

Journal of Clinical Investigation

Volumn 116, Issue 1, 2006, Pages 146-155

  Xystrakis, Emmanuel ^a   Kusumakar, Siddharth ^a   Boswell, Sandra ^a   Peek, Emma ^a   Urry, Zoë ^a   Richards, David F ^a   Adikibi, Tonye ^a   Pridgeon, Carol ^b   Dallman, Margaret ^b   Loke, Tuck Kay ^a   Robinson, Douglas S ^b   Barrat, Franck J ^c   O'Garra, Anne ^d   Lavender, Paul ^a   Lee, Tak H ^a   Corrigan, Christopher ^a   Hawrylowicz, Catherine M ^a,e  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c Dynavax Technologies Corporation   (United States)

^d NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^e GUY S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CD4 ANTIGEN; COLECALCIFEROL; DEXAMETHASONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; INTERLEUKIN 10; RECOMBINANT INTERLEUKIN 10;

ADULT; AGED; ALLERGIC ASTHMA; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE SEVERITY; DRUG MECHANISM; DRUG RESPONSE; DRUG SENSITIVITY; FEMALE; HUMAN; HUMAN CELL; IMMUNOREGULATION; IMMUNOSTIMULATION; LYMPHOCYTE CULTURE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; REGULATORY T LYMPHOCYTE; TH2 CELL; THERAPY RESISTANCE; TREATMENT RESPONSE;

ANTI-INFLAMMATORY AGENTS; ASTHMA; CD4-POSITIVE T-LYMPHOCYTES; CHOLECALCIFEROL; DEXAMETHASONE; DRUG RESISTANCE; GLUCOCORTICOIDS; HUMANS; INTERLEUKIN-10; REFERENCE VALUES;

EID: 31044447205     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI21759     Document Type: Article

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