Low-dose theophylline restores corticosteroid responsiveness in rats with smoke-induced airway inflammation

Canadian Journal of Physiology and Pharmacology

Volumn 90, Issue 7, 2012, Pages 895-902

  Sun, Xianwen ^a   Li, Qingyun ^c   Gong, Yi ^a   Ren, Lei ^a,b   Wan, Huanying ^a   Deng, Weiwu ^a  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^b Department of Respiratory Medicine   (China)

^c Shanghai 200025 ^*  (China)

Author keywords

Cigarette smoke; CXC chemokine ligand 8; Histone deacetylase 2; Inhaled corticosteroids; Theophylline

Indexed keywords

BUDESONIDE; CIGARETTE SMOKE; HISTONE DEACETYLASE 2; INTERLEUKIN 8; THEOPHYLLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL ASSESSMENT TOOL; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DRUG POTENTIATION; HISTOPATHOLOGY; LOW DRUG DOSE; LUNG DESTRUCTION INDEX; LUNG LAVAGE; LUNG PARENCHYMA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RESPIRATORY TRACT INFLAMMATION; SMOKE;

ADRENAL CORTEX HORMONES; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; BUDESONIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTONE DEACETYLASE 2; INFLAMMATION; INTERLEUKIN-8; LUNG; MALE; RATS; RATS, WISTAR; SMOKE; SMOKE INHALATION INJURY; SMOKING; THEOPHYLLINE;

EID: 84863642798     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/Y2012-079     Document Type: Article

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