-
1
-
-
40049107712
-
Immunologic and inflammatory mechanisms that drive asthma progression to remodeling
-
Broide DH. Immunologic and inflammatory mechanisms that drive asthma progression to remodeling. J Allergy Clin Immunol 2008;121:560-570.
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 560-570
-
-
Broide, D.H.1
-
3
-
-
24644520068
-
Airway remodeling contributes to the progressive loss of lung function in asthma: An overview
-
Pascual RM, Peters SP. Airway remodeling contributes to the progressive loss of lung function in asthma: an overview. J Allergy Clin Immunol 2005;116:477-486.
-
(2005)
J Allergy Clin Immunol
, vol.116
, pp. 477-486
-
-
Pascual, R.M.1
Peters, S.P.2
-
4
-
-
85047693288
-
Inhibition of airway remodeling in IL-5-deficient mice
-
Cho JY, Miller M, Baek KJ, et al. Inhibition of airway remodeling in IL-5-deficient mice. J Clin Invest 2004;113:551-560.
-
(2004)
J Clin Invest
, vol.113
, pp. 551-560
-
-
Cho, J.Y.1
Miller, M.2
Baek, K.J.3
-
5
-
-
4544274172
-
A critical role for eosinophils in allergic airways remodeling
-
Humbles AA, Lloyd CM, McMillan SJ, et al. A critical role for eosinophils in allergic airways remodeling. Science 2004;305:1776-1779.
-
(2004)
Science
, vol.305
, pp. 1776-1779
-
-
Humbles, A.A.1
Lloyd, C.M.2
McMillan, S.J.3
-
6
-
-
33750811888
-
A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation
-
Fulkerson PC, Fischetti CA, McBride ML, Hassman LM, Hogan SP, Rothenberg ME. A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation. Proc Natl Acad Sci U S A 2006;103:16418-16423.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 16418-16423
-
-
Fulkerson, P.C.1
Fischetti, C.A.2
McBride, M.L.3
Hassman, L.M.4
Hogan, S.P.5
Rothenberg, M.E.6
-
7
-
-
85027928970
-
The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling
-
Doherty TA, Soroosh P, Khorram N, et al. The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling. Nat Med 2011;17:596-603.
-
(2011)
Nat Med
, vol.17
, pp. 596-603
-
-
Doherty, T.A.1
Soroosh, P.2
Khorram, N.3
-
8
-
-
84860390495
-
Chronic OVA allergen challenged TNF p55/p75 receptor deficient mice have reduced airway remodeling
-
Cho JY, Pham A, Rosenthal P, Miller M, Doherty T, Broide DH. Chronic OVA allergen challenged TNF p55/p75 receptor deficient mice have reduced airway remodeling. Int Immunopharmacol 2011;11:1038-1044.
-
(2011)
Int Immunopharmacol
, vol.11
, pp. 1038-1044
-
-
Cho, J.Y.1
Pham, A.2
Rosenthal, P.3
Miller, M.4
Doherty, T.5
Broide, D.H.6
-
9
-
-
78649319089
-
Allergen-induced coexpression of bFGF and TGF-?1 by macrophages in a mouse model of airway remodeling: BFGF induces macrophage TGF-?1 expression in vitro
-
Yum HY, Cho JY, Miller M, Broide DH. Allergen-induced coexpression of bFGF and TGF-?1 by macrophages in a mouse model of airway remodeling: bFGF induces macrophage TGF-?1 expression in vitro. Int Arch Allergy Immunol 2011;155:12-22.
-
(2011)
Int Arch Allergy Immunol
, vol.155
, pp. 12-22
-
-
Yum, H.Y.1
Cho, J.Y.2
Miller, M.3
Broide, D.H.4
-
10
-
-
0033977013
-
Epithelial-mesenchymal interactions in the pathogenesis of asthma
-
Holgate ST, Davies DE, Lackie PM, Wilson SJ, Puddicombe SM, Lordan JL. Epithelial-mesenchymal interactions in the pathogenesis of asthma. J Allergy Clin Immunol 2000;105(2 Pt 1):193-204.
-
(2000)
J Allergy Clin Immunol
, vol.105
, Issue.2 PART 1
, pp. 193-204
-
-
Holgate, S.T.1
Davies, D.E.2
Lackie, P.M.3
Wilson, S.J.4
Puddicombe, S.M.5
Lordan, J.L.6
-
11
-
-
74749084658
-
A new look at the pathogenesis of asthma
-
Holgate ST, Arshad HS, Roberts GC, Howarth PH, Thurner P, Davies DE. A new look at the pathogenesis of asthma. Clin Sci (Lond) 2009;118:439-450.
-
(2009)
Clin Sci (Lond)
, vol.118
, pp. 439-450
-
-
Holgate, S.T.1
Arshad, H.S.2
Roberts, G.C.3
Howarth, P.H.4
Thurner, P.5
Davies, D.E.6
-
12
-
-
66149113689
-
Thymic stromal lymphopoietin, OX40-ligand, and interleukin-25 in allergic responses
-
Wang YH, Liu YJ. Thymic stromal lymphopoietin, OX40-ligand, and interleukin-25 in allergic responses. Clin Exp Allergy 2009;39:798-806.
-
(2009)
Clin Exp Allergy
, vol.39
, pp. 798-806
-
-
Wang, Y.H.1
Liu, Y.J.2
-
13
-
-
79551617339
-
Interactions of airway epithelium with protease allergens in the allergic response
-
Jacquet A. Interactions of airway epithelium with protease allergens in the allergic response. Clin Exp Allergy 2011;41:305-311.
-
(2011)
Clin Exp Allergy
, vol.41
, pp. 305-311
-
-
Jacquet, A.1
-
15
-
-
0023879839
-
Recombinant human interleukin 5 is a selective activator of human eosinophil function
-
Lopez AF, Sanderson CJ, Gamble JR, Campbell HD, Young IG, Vadas MA. Recombinant human interleukin 5 is a selective activator of human eosinophil function. J Exp Med 1988;167:219-224.
-
(1988)
J Exp Med
, vol.167
, pp. 219-224
-
-
Lopez, A.F.1
Sanderson, C.J.2
Gamble, J.R.3
Campbell, H.D.4
Young, I.G.5
Vadas, M.A.6
-
16
-
-
85047693849
-
Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics
-
Flood-Page P, Menzies-Gow A, Phipps S, et al. Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. J Clin Invest 2003;112:1029-1036.
-
(2003)
J Clin Invest
, vol.112
, pp. 1029-1036
-
-
Flood-Page, P.1
Menzies-Gow, A.2
Phipps, S.3
-
17
-
-
61849086181
-
Mepolizumab and exacerbations of refractory eosinophilic asthma
-
Haldar P, Brightling CE, Hargadon B, et al. Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med 2009;360:973-984.
-
(2009)
N Engl J Med
, vol.360
, pp. 973-984
-
-
Haldar, P.1
Brightling, C.E.2
Hargadon, B.3
-
18
-
-
33846074487
-
Effects of a low-molecularweight CCR-3 antagonist on chronic experimental asthma
-
Wegmann M, Goggel R, Sel S, et al. Effects of a low-molecularweight CCR-3 antagonist on chronic experimental asthma. Am J Respir Cell Mol Biol 2007;36:61-67.
-
(2007)
Am J Respir Cell Mol Biol
, vol.36
, pp. 61-67
-
-
Wegmann, M.1
Goggel, R.2
Sel, S.3
-
19
-
-
77249130857
-
A novel CC-chemokine receptor 3 antagonist, Ki19003, inhibits airway eosinophilia and subepithelial/peribronchial fibrosis induced by repeated antigen challenge in mice
-
Komai M, Tanaka H, Nagao K, et al. A novel CC-chemokine receptor 3 antagonist, Ki19003, inhibits airway eosinophilia and subepithelial/peribronchial fibrosis induced by repeated antigen challenge in mice. J Pharmacol Sci 2010;112:203-213.
-
(2010)
J Pharmacol Sci
, vol.112
, pp. 203-213
-
-
Komai, M.1
Tanaka, H.2
Nagao, K.3
-
20
-
-
27944460432
-
Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6'-sulfo-sialyl Lewis X as a preferred glycan ligand
-
Tateno H, Crocker PR, Paulson JC. Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6'-sulfo-sialyl Lewis X as a preferred glycan ligand. Glycobiology 2005;15:1125-1135.
-
(2005)
Glycobiology
, vol.15
, pp. 1125-1135
-
-
Tateno, H.1
Crocker, P.R.2
Paulson, J.C.3
-
21
-
-
14244269760
-
Glycan array screening reveals a candidate ligand for Siglec-8
-
Bochner BS, Alvarez RA, Mehta P, et al. Glycan array screening reveals a candidate ligand for Siglec-8. J Biol Chem 2005;280:4307-4312.
-
(2005)
J Biol Chem
, vol.280
, pp. 4307-4312
-
-
Bochner, B.S.1
Alvarez, R.A.2
Mehta, P.3
-
22
-
-
77950919299
-
Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling
-
Song DJ, Cho JY, Lee SY, et al. Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling. J Immunol 2009;183:5333-5341.
-
(2009)
J Immunol
, vol.183
, pp. 5333-5341
-
-
Song, D.J.1
Cho, J.Y.2
Lee, S.Y.3
-
23
-
-
77958571341
-
Chronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13
-
Cho JY, Song DJ, Pham A, et al. Chronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13. Respir Res 2010;11:154.
-
(2010)
Respir Res
, vol.11
, pp. 154
-
-
Cho, J.Y.1
Song, D.J.2
Pham, A.3
-
24
-
-
0043074624
-
Occurrence of an activated, profibrotic pattern of gene expression in lung CD8+ T cells from scleroderma patients
-
Luzina IG, Atamas SP, Wise R, et al. Occurrence of an activated, profibrotic pattern of gene expression in lung CD8+ T cells from scleroderma patients. Arthritis Rheum 2003;48:2262-2274.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2262-2274
-
-
Luzina, I.G.1
Atamas, S.P.2
Wise, R.3
-
26
-
-
0026538877
-
Site of airway obstruction in pulmonary disease: Direct measurement of intrabronchial pressure
-
Yanai M, Sekizawa K, Ohrui T, Sasaki H, Takishima T. Site of airway obstruction in pulmonary disease: direct measurement of intrabronchial pressure. J Appl Physiol 1992;72:1016-1023.
-
(1992)
J Appl Physiol
, vol.72
, pp. 1016-1023
-
-
Yanai, M.1
Sekizawa, K.2
Ohrui, T.3
Sasaki, H.4
Takishima, T.5
-
27
-
-
17844400081
-
Manipulation of allergeninduced airway remodeling by treatment with anti-TGF-beta antibody: Effect on the Smad signaling pathway
-
McMillan SJ, Xanthou G, Lloyd CM. Manipulation of allergeninduced airway remodeling by treatment with anti-TGF-beta antibody: effect on the Smad signaling pathway. J Immunol 2005;174:5774-5780.
-
(2005)
J Immunol
, vol.174
, pp. 5774-5780
-
-
McMillan, S.J.1
Xanthou, G.2
Lloyd, C.M.3
-
28
-
-
33847350691
-
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
-
Wynn TA. Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. J Clin Invest 2007;117:524-529.
-
(2007)
J Clin Invest
, vol.117
, pp. 524-529
-
-
Wynn, T.A.1
-
29
-
-
34249792354
-
Inhibition of allergen-induced airway remodeling in Smad 3-deficient mice
-
Le AV, Cho JY, Miller M, McElwain S, Golgotiu K, Broide DH. Inhibition of allergen-induced airway remodeling in Smad 3-deficient mice. J Immunol 2007;178:7310-7316.
-
(2007)
J Immunol
, vol.178
, pp. 7310-7316
-
-
Le, A.V.1
Cho, J.Y.2
Miller, M.3
McElwain, S.4
Golgotiu, K.5
Broide, D.H.6
-
30
-
-
77956628834
-
Overexpression of Smad2 drives house dust mite-mediated airway remodeling and airway hyperresponsiveness via activin and IL-25
-
Gregory LG, Mathie SA, Walker SA, Pegorier S, Jones CP, Lloyd CM. Overexpression of Smad2 drives house dust mite-mediated airway remodeling and airway hyperresponsiveness via activin and IL-25. Am J Respir Crit Care Med 2010;182:143-154.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 143-154
-
-
Gregory, L.G.1
Mathie, S.A.2
Walker, S.A.3
Pegorier, S.4
Jones, C.P.5
Lloyd, C.M.6
-
31
-
-
0030753766
-
Transforming growth factor-beta 1 in asthma: Measurement in bronchoalveolar lavage fluid
-
Redington AE, Madden J, Frew AJ, et al. Transforming growth factor-beta 1 in asthma: measurement in bronchoalveolar lavage fluid. Am J Respir Crit Care Med 1997;156:642-647.
-
(1997)
Am J Respir Crit Care Med
, vol.156
, pp. 642-647
-
-
Redington, A.E.1
Madden, J.2
Frew, A.J.3
-
32
-
-
0037841704
-
Airway remodeling-associated mediators in moderate to severe asthma: Effect of steroidson TGF-beta, IL-11, IL-17, and type I and type III collagen expression
-
Chakir J, Shannon J, Molet S, et al. Airway remodeling-associated mediators in moderate to severe asthma: effect of steroidson TGF-beta, IL-11, IL-17, and type I and type III collagen expression. J Allergy Clin Immunol 2003;111:1293-1298.
-
(2003)
J Allergy Clin Immunol
, vol.111
, pp. 1293-1298
-
-
Chakir, J.1
Shannon, J.2
Molet, S.3
-
33
-
-
79955595072
-
Airway remodeling in asthma: New mechanisms and potential for pharmacological intervention
-
Girodet PO, Ozier A, Bara I, Tunon de Lara JM, Marthan R, Berger P. Airway remodeling in asthma: new mechanisms and potential for pharmacological intervention. Pharmacol Ther 2011;130:325-337.
-
(2011)
Pharmacol Ther
, vol.130
, pp. 325-337
-
-
Girodet, P.O.1
Ozier, A.2
Bara, I.3
de Tunon Lara, J.M.4
Marthan, R.5
Berger, P.6
-
34
-
-
38049024624
-
FGF2 in asthmatic airwaysmooth- muscle-cell hyperplasia
-
Bosse Y, Rola-Pleszczynski M. FGF2 in asthmatic airwaysmooth- muscle-cell hyperplasia. Trends Mol Med 2008;14:3-11.
-
(2008)
Trends Mol Med
, vol.14
, pp. 3-11
-
-
Bosse, Y.1
Rola-Pleszczynski, M.2
-
35
-
-
33744775694
-
Fibroblast growth factor 2 and transforming growth factor beta1 synergism in human bronchial smooth muscle cell proliferation
-
Bosse Y, Thompson C, Stankova J, Rola-Pleszczynski M. Fibroblast growth factor 2 and transforming growth factor beta1 synergism in human bronchial smooth muscle cell proliferation. Am J Respir Cell Mol Biol 2006;34:746-753.
-
(2006)
Am J Respir Cell Mol Biol
, vol.34
, pp. 746-753
-
-
Bosse, Y.1
Thompson, C.2
Stankova, J.3
Rola-Pleszczynski, M.4
-
36
-
-
0035136844
-
TGF-beta 1 induces proliferation in human renal fibroblasts via induction of basic fibroblast growth factor (FGF-2)
-
Strutz F, Zeisberg M, Renziehausen A, et al. TGF-beta 1 induces proliferation in human renal fibroblasts via induction of basic fibroblast growth factor (FGF-2). Kidney Int 2001;59:579-592.
-
(2001)
Kidney Int
, vol.59
, pp. 579-592
-
-
Strutz, F.1
Zeisberg, M.2
Renziehausen, A.3
-
37
-
-
0031715673
-
Ultrastructural immunolocalization of basic fibroblast growth factor in mast cell secretory granules: Morphological evidence for bfgf release through degranulation
-
Qu Z, Kayton RJ, Ahmadi P, et al. Ultrastructural immunolocalization of basic fibroblast growth factor in mast cell secretory granules: morphological evidence for bfgf release through degranulation. J Histochem Cytochem 1998;46:1119-1128.
-
(1998)
J Histochem Cytochem
, vol.46
, pp. 1119-1128
-
-
Qu, Z.1
Kayton, R.J.2
Ahmadi, P.3
-
39
-
-
77950925754
-
Transforming growth factor-beta1 in asthmatic airway smooth muscle enlargement: Is fibroblast growth factor-2 required?
-
Bosse Y, Stankova J, Rola-Pleszczynski M. Transforming growth factor-beta1 in asthmatic airway smooth muscle enlargement: is fibroblast growth factor-2 required? Clin Exp Allergy 2010;40:710-724.
-
(2010)
Clin Exp Allergy
, vol.40
, pp. 710-724
-
-
Bosse, Y.1
Stankova, J.2
Rola-Pleszczynski, M.3
-
40
-
-
0037446532
-
Regulation of activin A expression in mast cells and asthma: Its effect on the proliferation of human airway smooth muscle cells
-
Cho SH, Yao Z, Wang SW, et al. Regulation of activin A expression in mast cells and asthma: its effect on the proliferation of human airway smooth muscle cells. J Immunol 2003;170:4045-4052.
-
(2003)
J Immunol
, vol.170
, pp. 4045-4052
-
-
Cho, S.H.1
Yao, Z.2
Wang, S.W.3
-
41
-
-
34047160366
-
Recombinant basic fibroblast growth factor inhibits the airway hyperresponsiveness, mucus production, and lung inflammation induced by an allergen challenge
-
Jeon SG, Lee CG, Oh MH, et al. Recombinant basic fibroblast growth factor inhibits the airway hyperresponsiveness, mucus production, and lung inflammation induced by an allergen challenge. J Allergy Clin Immunol 2007;119:831-837.
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 831-837
-
-
Jeon, S.G.1
Lee, C.G.2
Oh, M.H.3
-
42
-
-
35448998469
-
Up-regulation of thrombin activity induced by vascular endothelial growth factor in asthmatic airways
-
Kanazawa H, Yoshikawa T. Up-regulation of thrombin activity induced by vascular endothelial growth factor in asthmatic airways. Chest 2007;132:1169-1174.
-
(2007)
Chest
, vol.132
, pp. 1169-1174
-
-
Kanazawa, H.1
Yoshikawa, T.2
-
43
-
-
0035113289
-
Basic fibroblast growth factor in asthma: Measurement in bronchoalveolar lavage fluid basally and following allergen challenge
-
Redington AE, Roche WR, Madden J, et al. Basic fibroblast growth factor in asthma: measurement in bronchoalveolar lavage fluid basally and following allergen challenge. J Allergy Clin Immunol 2001;107:384-387.
-
(2001)
J Allergy Clin Immunol
, vol.107
, pp. 384-387
-
-
Redington, A.E.1
Roche, W.R.2
Madden, J.3
-
44
-
-
0031695198
-
Functions of the VEGF receptor-1 (FLT-1) in the vasculature
-
Clauss M. Functions of the VEGF receptor-1 (FLT-1) in the vasculature. Trends Cardiovasc Med 1998;8:241-245.
-
(1998)
Trends Cardiovasc Med
, vol.8
, pp. 241-245
-
-
Clauss, M.1
-
45
-
-
0030983569
-
Bronchial vascular congestion and angiogenesis
-
Charan NB, Baile EM, Pare PD. Bronchial vascular congestion and angiogenesis. Eur Respir J 1997;10:1173-1180.
-
(1997)
Eur Respir J
, vol.10
, pp. 1173-1180
-
-
Charan, N.B.1
Baile, E.M.2
Pare, P.D.3
-
46
-
-
0036795950
-
Cockroach extract antigen increases bronchial airway epithelial permeability
-
Antony AB, Tepper RS, Mohammed KA. Cockroach extract antigen increases bronchial airway epithelial permeability. J Allergy Clin Immunol 2002;110:589-595.
-
(2002)
J Allergy Clin Immunol
, vol.110
, pp. 589-595
-
-
Antony, A.B.1
Tepper, R.S.2
Mohammed, K.A.3
-
47
-
-
7044260315
-
Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung
-
Lee CG, Link H, Baluk P, et al. Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. Nat Med 2004;10:1095-1103.
-
(2004)
Nat Med
, vol.10
, pp. 1095-1103
-
-
Lee, C.G.1
Link, H.2
Baluk, P.3
-
48
-
-
33746588592
-
Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung
-
Bhandari V, Choo-Wing R, Chapoval SP, et al. Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung. Proc Natl Acad Sci U S A 2006;103:11021-11026.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 11021-11026
-
-
Bhandari, V.1
Choo-Wing, R.2
Chapoval, S.P.3
-
49
-
-
0036794970
-
Imbalance between vascular endothelial growth factor and endostatin levels in induced sputum from asthmatic subjects
-
Asai K, Kanazawa H, Otani K, Shiraishi S, Hirata K, Yoshikawa J. Imbalance between vascular endothelial growth factor and endostatin levels in induced sputum from asthmatic subjects. J Allergy Clin Immunol 2002;110:571-575.
-
(2002)
J Allergy Clin Immunol
, vol.110
, pp. 571-575
-
-
Asai, K.1
Kanazawa, H.2
Otani, K.3
Shiraishi, S.4
Hirata, K.5
Yoshikawa, J.6
-
50
-
-
33344459072
-
A comparative study of two angiogenic factors: Vascular endothelial growth factor and angiogenin in induced sputum from asthmatic children in acute attack
-
Abdel-Rahman AM, el-Sahrigy SA, Bakr SI. A comparative study of two angiogenic factors: vascular endothelial growth factor and angiogenin in induced sputum from asthmatic children in acute attack. Chest 2006;129:266-271.
-
(2006)
Chest
, vol.129
, pp. 266-271
-
-
Abdel-Rahman, A.M.1
El-Sahrigy, S.A.2
Bakr, S.I.3
-
51
-
-
67650381829
-
Vascular endothelial growth factor levels in induced sputum and emphysematous changes in smoking asthmatic patients
-
Bae YJ, Kim TB, Moon KA, et al. Vascular endothelial growth factor levels in induced sputum and emphysematous changes in smoking asthmatic patients. Ann Allergy Asthma Immunol 2009;103:51-56.
-
(2009)
Ann Allergy Asthma Immunol
, vol.103
, pp. 51-56
-
-
Bae, Y.J.1
Kim, T.B.2
Moon, K.A.3
-
52
-
-
0027289741
-
Human eosinophils can express the cytokines tumor necrosis factor-alpha and macrophage inflammatory protein-1 alpha
-
Costa JJ, Matossian K, Resnick MB, et al. Human eosinophils can express the cytokines tumor necrosis factor-alpha and macrophage inflammatory protein-1 alpha. J Clin Invest 1993;91:2673-2684.
-
(1993)
J Clin Invest
, vol.91
, pp. 2673-2684
-
-
Costa, J.J.1
Matossian, K.2
Resnick, M.B.3
-
53
-
-
42949139388
-
Mast cell-derived tumour necrosis factor is essential for allergic airway disease
-
Reuter S, Heinz A, Sieren M, et al. Mast cell-derived tumour necrosis factor is essential for allergic airway disease. Eur Respir J 2008;31:773-782.
-
(2008)
Eur Respir J
, vol.31
, pp. 773-782
-
-
Reuter, S.1
Heinz, A.2
Sieren, M.3
-
54
-
-
34250829615
-
Mast cell-derived TNF contributes to airway hyperreactivity, inflammation, and TH2 cytokine production in an asthma model in mice
-
Nakae S, Ho LH, Yu M, et al. Mast cell-derived TNF contributes to airway hyperreactivity, inflammation, and TH2 cytokine production in an asthma model in mice. J Allergy Clin Immunol 2007;120:48-55.
-
(2007)
J Allergy Clin Immunol
, vol.120
, pp. 48-55
-
-
Nakae, S.1
Ho, L.H.2
Yu, M.3
-
55
-
-
32644490529
-
Evidence of a role of tumor necrosis factor alpha in refractory asthma
-
Berry MA, Hargadon B, Shelley M, et al. Evidence of a role of tumor necrosis factor alpha in refractory asthma. N Engl J Med 2006;354:697-708.
-
(2006)
N Engl J Med
, vol.354
, pp. 697-708
-
-
Berry, M.A.1
Hargadon, B.2
Shelley, M.3
-
57
-
-
33746651060
-
Reduced peribronchial fibrosis in allergen-challenged MMP-9-deficient mice
-
Lim DH, Cho JY, Miller M, McElwain K, McElwain S, Broide DH. Reduced peribronchial fibrosis in allergen-challenged MMP-9-deficient mice. Am J Physiol Lung Cell Mol Physiol 2006;291:L265-L271.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.291
-
-
Lim, D.H.1
Cho, J.Y.2
Miller, M.3
McElwain, K.4
McElwain, S.5
Broide, D.H.6
-
58
-
-
0034791969
-
The involvement of matrix metalloproteinase-9 in airway inflammation of patients with acute asthma
-
Lee YC, Lee HB, Rhee YK, Song CH. The involvement of matrix metalloproteinase-9 in airway inflammation of patients with acute asthma. Clin Exp Allergy 2001;31:1623-1630.
-
(2001)
Clin Exp Allergy
, vol.31
, pp. 1623-1630
-
-
Lee, Y.C.1
Lee, H.B.2
Rhee, Y.K.3
Song, C.H.4
-
59
-
-
0037173639
-
Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness
-
Van Eerdewegh P, Little RD, Dupuis J, et al. Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature 2002;418:426-430.
-
(2002)
Nature
, vol.418
, pp. 426-430
-
-
van Eerdewegh, P.1
Little, R.D.2
Dupuis, J.3
-
60
-
-
69249234646
-
The effects of Th2 cytokines on the expression of ADAM33 in allergen-induced chronic airway inflammation
-
Jie Z, Jin M, Cai Y, et al. The effects of Th2 cytokines on the expression of ADAM33 in allergen-induced chronic airway inflammation. Respir Physiol Neurobiol 2009;168:289-294.
-
(2009)
Respir Physiol Neurobiol
, vol.168
, pp. 289-294
-
-
Jie, Z.1
Jin, M.2
Cai, Y.3
-
61
-
-
34047143642
-
Increased expression of ADAM33 and ADAM8 with disease progression in asthma
-
Foley SC, Mogas AK, Olivenstein R, et al. Increased expression of ADAM33 and ADAM8 with disease progression in asthma. JAllergy Clin Immunol 2007;119:863-871.
-
(2007)
JAllergy Clin Immunol
, vol.119
, pp. 863-871
-
-
Foley, S.C.1
Mogas, A.K.2
Olivenstein, R.3
-
62
-
-
78649884336
-
IL-33 family members and asthma - bridging innate and adaptive immune responses
-
Lloyd CM. IL-33 family members and asthma - bridging innate and adaptive immune responses. Curr Opin Immunol 2010;22:800-806.
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 800-806
-
-
Lloyd, C.M.1
-
63
-
-
77953633984
-
Thymic stromal lymphopoietin receptor-mediated IL-6 and CC/CXC chemokines expression in human airway smooth muscle cells: Role of MAPKs (ERK1/2, p38, and JNK) and STAT3 pathways
-
Shan L, Redhu NS, Saleh A, Halayko AJ, Chakir J, Gounni AS. Thymic stromal lymphopoietin receptor-mediated IL-6 and CC/CXC chemokines expression in human airway smooth muscle cells: role of MAPKs (ERK1/2, p38, and JNK) and STAT3 pathways. J Immunol 2010;184:7134-7143.
-
(2010)
J Immunol
, vol.184
, pp. 7134-7143
-
-
Shan, L.1
Redhu, N.S.2
Saleh, A.3
Halayko, A.J.4
Chakir, J.5
Gounni, A.S.6
-
64
-
-
25144525707
-
A role for TSLP in the development of inflammation in an asthma model
-
Al-Shami A, Spolski R, Kelly J, Keane-Myers A, Leonard WJ. A role for TSLP in the development of inflammation in an asthma model. J Exp Med 2005;202:829-839.
-
(2005)
J Exp Med
, vol.202
, pp. 829-839
-
-
Al-Shami, A.1
Spolski, R.2
Kelly, J.3
Keane-Myers, A.4
Leonard, W.J.5
-
65
-
-
79953781744
-
A soluble thymic stromal lymphopoietin (TSLP) antagonist, TSLPR-immunoglobulin, reduces the severity of allergic disease by regulating pulmonary dendritic cells
-
Zhang F, Huang G, Hu B, Song Y, Shi Y. A soluble thymic stromal lymphopoietin (TSLP) antagonist, TSLPR-immunoglobulin, reduces the severity of allergic disease by regulating pulmonary dendritic cells. Clin Exp Immunol 2011;164:256-264.
-
(2011)
Clin Exp Immunol
, vol.164
, pp. 256-264
-
-
Zhang, F.1
Huang, G.2
Hu, B.3
Song, Y.4
Shi, Y.5
-
66
-
-
73949108120
-
House dust mite-promoted epithelial-to-mesenchymal transition in human bronchial epithelium
-
Heijink IH, Postma DS, Noordhoek JA, Broekema M, Kapus A. House dust mite-promoted epithelial-to-mesenchymal transition in human bronchial epithelium. Am J Respir Cell Mol Biol 2010;42:69-79.
-
(2010)
Am J Respir Cell Mol Biol
, vol.42
, pp. 69-79
-
-
Heijink, I.H.1
Postma, D.S.2
Noordhoek, J.A.3
Broekema, M.4
Kapus, A.5
-
67
-
-
78349275762
-
Epidermal growth factor receptor signalling contributes to house dust mite-induced epithelial barrier dysfunction
-
Heijink IH, van Oosterhout A, Kapus A. Epidermal growth factor receptor signalling contributes to house dust mite-induced epithelial barrier dysfunction. Eur Respir J 2010;36:1016-1026.
-
(2010)
Eur Respir J
, vol.36
, pp. 1016-1026
-
-
Heijink, I.H.1
van Oosterhout, A.2
Kapus, A.3
-
68
-
-
20444365526
-
Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity
-
Ying S, O'Connor B, Ratoff J, et al. Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity. J Immunol 2005;174:8183-8190.
-
(2005)
J Immunol
, vol.174
, pp. 8183-8190
-
-
Ying, S.1
O'Connor, B.2
Ratoff, J.3
-
69
-
-
53149097377
-
Expression and cellular provenance of thymic stromal lymphopoietin and chemokines in patients with severe asthma and chronic obstructive pulmonary disease
-
Ying S, O'Connor B, Ratoff J, et al. Expression and cellular provenance of thymic stromal lymphopoietin and chemokines in patients with severe asthma and chronic obstructive pulmonary disease. J Immunol 2008;181:2790-2798.
-
(2008)
J Immunol
, vol.181
, pp. 2790-2798
-
-
Ying, S.1
O'Connor, B.2
Ratoff, J.3
-
70
-
-
25844515028
-
Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice
-
Zhou B, Comeau MR, De Smedt T, et al. Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice. Nat Immunol 2005;6:1047-1053.
-
(2005)
Nat Immunol
, vol.6
, pp. 1047-1053
-
-
Zhou, B.1
Comeau, M.R.2
de Smedt, T.3
-
71
-
-
33645896155
-
Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract
-
Owyang AM, Zaph C, Wilson EH, et al. Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract. J Exp Med 2006;203:843-849.
-
(2006)
J Exp Med
, vol.203
, pp. 843-849
-
-
Owyang, A.M.1
Zaph, C.2
Wilson, E.H.3
-
72
-
-
34447281733
-
Interleukin 25 promotes the initiation of proallergic type 2 responses
-
Angkasekwinai P, Park H, Wang YH, et al. Interleukin 25 promotes the initiation of proallergic type 2 responses. J Exp Med 2007;204:1509-1517.
-
(2007)
J Exp Med
, vol.204
, pp. 1509-1517
-
-
Angkasekwinai, P.1
Park, H.2
Wang, Y.H.3
-
73
-
-
18244405108
-
IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo
-
Fort MM, Cheung J, Yen D, et al. IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo. Immunity 2001;15:985-995.
-
(2001)
Immunity
, vol.15
, pp. 985-995
-
-
Fort, M.M.1
Cheung, J.2
Yen, D.3
-
74
-
-
0036644547
-
New IL-17 family members promote Th1 or Th2 responses in the lung: In vivo function of the novel cytokine IL-25
-
Hurst SD, Muchamuel T, Gorman DM, et al. New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25. J Immunol 2002;169:443-453.
-
(2002)
J Immunol
, vol.169
, pp. 443-453
-
-
Hurst, S.D.1
Muchamuel, T.2
Gorman, D.M.3
-
75
-
-
79952136459
-
T-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthma
-
Corrigan CJ, Wang W, Meng Q, et al. T-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthma. Proc Natl Acad Sci U S A 2011;108:1579-1584.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 1579-1584
-
-
Corrigan, C.J.1
Wang, W.2
Meng, Q.3
-
76
-
-
27744446058
-
IL-33, an interleukin-1- like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
-
Schmitz J, Owyang A, Oldham E, et al. IL-33, an interleukin-1- like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 2005;23:479-490.
-
(2005)
Immunity
, vol.23
, pp. 479-490
-
-
Schmitz, J.1
Owyang, A.2
Oldham, E.3
-
77
-
-
34249882513
-
IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system
-
Sanada S, Hakuno D, Higgins LJ, Schreiter ER, McKenzie AN, Lee RT. IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system. J Clin Invest 2007;117:1538-1549.
-
(2007)
J Clin Invest
, vol.117
, pp. 1538-1549
-
-
Sanada, S.1
Hakuno, D.2
Higgins, L.J.3
Schreiter, E.R.4
McKenzie, A.N.5
Lee, R.T.6
-
78
-
-
53749093767
-
The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: A novel 'alarmin'?
-
Moussion C, Ortega N, Girard JP. The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel 'alarmin'? PLoS One 2008;3:e3331.
-
(2008)
PLoS One
, vol.3
-
-
Moussion, C.1
Ortega, N.2
Girard, J.P.3
-
79
-
-
65549163320
-
IL-33, a recently identified interleukin-1 gene family member, is expressed in human adipocytes
-
Wood IS, Wang B, Trayhurn P. IL-33, a recently identified interleukin-1 gene family member, is expressed in human adipocytes. Biochem Biophys Res Commun 2009;384:105-109.
-
(2009)
Biochem Biophys Res Commun
, vol.384
, pp. 105-109
-
-
Wood, I.S.1
Wang, B.2
Trayhurn, P.3
-
80
-
-
75549085516
-
IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation
-
Kurowska-Stolarska M, Stolarski B, Kewin P, et al. IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation. J Immunol 2009;183:6469-6477.
-
(2009)
J Immunol
, vol.183
, pp. 6469-6477
-
-
Kurowska-Stolarska, M.1
Stolarski, B.2
Kewin, P.3
-
81
-
-
44849117539
-
Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system
-
Kondo Y, Yoshimoto T, Yasuda K, et al. Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system. Int Immunol 2008;20:791-800.
-
(2008)
Int Immunol
, vol.20
, pp. 791-800
-
-
Kondo, Y.1
Yoshimoto, T.2
Yasuda, K.3
-
82
-
-
77953728457
-
Over-expression of IL-33 leads to spontaneous pulmonary inflammation in mIL-33 transgenic mice
-
Zhiguang X, Wei C, Steven R, et al. Over-expression of IL-33 leads to spontaneous pulmonary inflammation in mIL-33 transgenic mice. Immunol Lett 2010;131:159-165.
-
(2010)
Immunol Lett
, vol.131
, pp. 159-165
-
-
Zhiguang, X.1
Wei, C.2
Steven, R.3
-
83
-
-
67649207586
-
Anti-IL-33 antibody treatment inhibits airway inflammation in a murine model of allergic asthma
-
Liu X, Li M, Wu Y, Zhou Y, Zeng L, Huang T. Anti-IL-33 antibody treatment inhibits airway inflammation in a murine model of allergic asthma. Biochem Biophys Res Commun 2009;386:181-185.
-
(2009)
Biochem Biophys Res Commun
, vol.386
, pp. 181-185
-
-
Liu, X.1
Li, M.2
Wu, Y.3
Zhou, Y.4
Zeng, L.5
Huang, T.6
-
84
-
-
0033523665
-
Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses
-
Coyle AJ, Lloyd C, Tian J, et al. Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses. J Exp Med 1999;190:895-902.
-
(1999)
J Exp Med
, vol.190
, pp. 895-902
-
-
Coyle, A.J.1
Lloyd, C.2
Tian, J.3
-
85
-
-
77949311799
-
IL-33 induces IL-13- dependent cutaneous fibrosis
-
Rankin AL, Mumm JB, Murphy E, et al. IL-33 induces IL-13- dependent cutaneous fibrosis. J Immunol 2010;184:1526-1535.
-
(2010)
J Immunol
, vol.184
, pp. 1526-1535
-
-
Rankin, A.L.1
Mumm, J.B.2
Murphy, E.3
-
86
-
-
77649271174
-
Increased IL-33 expression by epithelial cells in bronchial asthma
-
Prefontaine D, Nadigel J, Chouiali F, et al. Increased IL-33 expression by epithelial cells in bronchial asthma. J Allergy Clin Immunol 2010;125:752-754.
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 752-754
-
-
Prefontaine, D.1
Nadigel, J.2
Chouiali, F.3
-
87
-
-
74049121313
-
IL-33: A tissue derived cytokine pathway involved in allergic inf lammation and asthma
-
Smith DE. IL-33: a tissue derived cytokine pathway involved in allergic inf lammation and asthma. Clin Exp Allergy 2010;40:200-208.
-
(2010)
Clin Exp Allergy
, vol.40
, pp. 200-208
-
-
Smith, D.E.1
-
88
-
-
0036606480
-
Risk factors for airway remodeling in asthma manifested by a low postbronchodilator FEV1/vital capacity ratio: A longitudinal population study from childhood to adulthood
-
Rasmussen F, Taylor DR, Flannery EM, et al. Risk factors for airway remodeling in asthma manifested by a low postbronchodilator FEV1/vital capacity ratio: a longitudinal population study from childhood to adulthood. Am J Respir Crit Care Med 2002;165:1480-1488.
-
(2002)
Am J Respir Crit Care Med
, vol.165
, pp. 1480-1488
-
-
Rasmussen, F.1
Taylor, D.R.2
Flannery, E.M.3
-
90
-
-
77956796272
-
Quantitative analysis of high-resolution computed tomography scans in severe asthma subphenotypes
-
Gupta S, Siddiqui S, Haldar P, et al. Quantitative analysis of high-resolution computed tomography scans in severe asthma subphenotypes. Thorax 2010;65:775-781.
-
(2010)
Thorax
, vol.65
, pp. 775-781
-
-
Gupta, S.1
Siddiqui, S.2
Haldar, P.3
-
91
-
-
78649669313
-
Demonstration of the heterogeneous distribution of asthma in the lungs using CT and hyperpolarized helium-3 MRI
-
Aysola R, de Lange EE, Castro M, Altes TA. Demonstration of the heterogeneous distribution of asthma in the lungs using CT and hyperpolarized helium-3 MRI. J Magn Reson Imaging 2010;32:1379-1387.
-
(2010)
J Magn Reson Imaging
, vol.32
, pp. 1379-1387
-
-
Aysola, R.1
de Lange, E.E.2
Castro, M.3
Altes, T.A.4
-
92
-
-
33750043741
-
Evaluation of asthma with hyperpolarized helium-3 MRI: Correlation with clinical severity and spirometry
-
de Lange EE, Altes TA, Patrie JT, et al. Evaluation of asthma with hyperpolarized helium-3 MRI: correlation with clinical severity and spirometry. Chest 2006;130:1055-1062.
-
(2006)
Chest
, vol.130
, pp. 1055-1062
-
-
de Lange, E.E.1
Altes, T.A.2
Patrie, J.T.3
-
93
-
-
43249106148
-
Evaluation of structure-function relationships in asthma using multidetector CT and hyperpolarized He-3 MRI
-
Fain SB, Gonzalez-Fernandez G, Peterson ET, et al. Evaluation of structure-function relationships in asthma using multidetector CT and hyperpolarized He-3 MRI. Acad Radiol 2008;15:753-762.
-
(2008)
Acad Radiol
, vol.15
, pp. 753-762
-
-
Fain, S.B.1
Gonzalez-Fernandez, G.2
Peterson, E.T.3
-
94
-
-
77956818233
-
Increased levels of osteopontin in sputum supernatant in severe refractory asthma
-
Delimpoura V, Bakakos P, Tseliou E, et al. Increased levels of osteopontin in sputum supernatant in severe refractory asthma. Thorax 2010;65:782-786.
-
(2010)
Thorax
, vol.65
, pp. 782-786
-
-
Delimpoura, V.1
Bakakos, P.2
Tseliou, E.3
-
95
-
-
79551520313
-
Persisting remodeling and less airway wall eosinophil activation in complete remission of asthma
-
Broekema M, Timens W, Vonk JM, et al. Persisting remodeling and less airway wall eosinophil activation in complete remission of asthma. Am J Respir Crit Care Med 2011;183:310-316.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 310-316
-
-
Broekema, M.1
Timens, W.2
Vonk, J.M.3
-
96
-
-
78651081222
-
Effects of formoterol-budesonide on airway remodeling in patients with moderate asthma
-
Wang K, Liu CT, Wu YH, et al. Effects of formoterol-budesonide on airway remodeling in patients with moderate asthma. Acta Pharmacol Sin 2011;32:126-132.
-
(2011)
Acta Pharmacol Sin
, vol.32
, pp. 126-132
-
-
Wang, K.1
Liu, C.T.2
Wu, Y.H.3
-
98
-
-
70049093185
-
The use of endobronchial ultrasonography in assessment of bronchial wall remodeling in patients with asthma
-
Soja J, Grzanka P, Sladek K, et al. The use of endobronchial ultrasonography in assessment of bronchial wall remodeling in patients with asthma. Chest 2009;136:797-804.
-
(2009)
Chest
, vol.136
, pp. 797-804
-
-
Soja, J.1
Grzanka, P.2
Sladek, K.3
-
99
-
-
14844300188
-
The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation
-
Holgate S, Casale T, Wenzel S, Bousquet J, Deniz Y, Reisner C. The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation. J Allergy Clin Immunol 2005;115:459-465.
-
(2005)
J Allergy Clin Immunol
, vol.115
, pp. 459-465
-
-
Holgate, S.1
Casale, T.2
Wenzel, S.3
Bousquet, J.4
Deniz, Y.5
Reisner, C.6
-
100
-
-
79961127439
-
Can anti-IgE therapy prevent airway remodeling in allergic asthma?
-
Rabe KF, Calhoun WJ, Smith N, Jimenez P. Can anti-IgE therapy prevent airway remodeling in allergic asthma? Allergy 2011;66:1142-1151.
-
(2011)
Allergy
, vol.66
, pp. 1142-1151
-
-
Rabe, K.F.1
Calhoun, W.J.2
Smith, N.3
Jimenez, P.4
-
101
-
-
58149113160
-
Eosinophils in bronchial mucosa of asthmatics after allergen challenge: Effect of anti-IgE treatment
-
van Rensen EL, Evertse CE, van Schadewijk WA, et al. Eosinophils in bronchial mucosa of asthmatics after allergen challenge: effect of anti-IgE treatment. Allergy 2009;64:72-80.
-
(2009)
Allergy
, vol.64
, pp. 72-80
-
-
van Rensen, E.L.1
Evertse, C.E.2
van Schadewijk, W.A.3
-
102
-
-
70449106421
-
Effects of omalizumab on markers of inflammation in patients with allergic asthma
-
Holgate S, Smith N, Massanari M, Jimenez P. Effects of omalizumab on markers of inflammation in patients with allergic asthma. Allergy 2009;64:1728-1736.
-
(2009)
Allergy
, vol.64
, pp. 1728-1736
-
-
Holgate, S.1
Smith, N.2
Massanari, M.3
Jimenez, P.4
-
103
-
-
77953334914
-
Inhibitory effects of anti-immunoglobulin E antibodies on airway remodeling in a murine model of chronic asthma
-
Kang JY, Kim JW, Kim JS, et al. Inhibitory effects of anti-immunoglobulin E antibodies on airway remodeling in a murine model of chronic asthma. J Asthma 2010;47:374-380.
-
(2010)
J Asthma
, vol.47
, pp. 374-380
-
-
Kang, J.Y.1
Kim, J.W.2
Kim, J.S.3
-
104
-
-
78650515905
-
Cytokine inhibition in severe asthma: Current knowledge and future directions
-
Corren J. Cytokine inhibition in severe asthma: current knowledge and future directions. Curr Opin Pulm Med 2011;17:29-33.
-
(2011)
Curr Opin Pulm Med
, vol.17
, pp. 29-33
-
-
Corren, J.1
-
105
-
-
61849155730
-
Mepolizumab for prednisone-dependent asthma with sputum eosinophilia
-
Nair P, Pizzichini MM, Kjarsgaard M, et al. Mepolizumab for prednisone-dependent asthma with sputum eosinophilia. N Engl J Med 2009;360:985-993.
-
(2009)
N Engl J Med
, vol.360
, pp. 985-993
-
-
Nair, P.1
Pizzichini, M.M.2
Kjarsgaard, M.3
-
107
-
-
79957987328
-
Efficacy and safety of etanercept in moderate-to-severe asthma: A randomised, controlled trial
-
Holgate ST, Noonan M, Chanez P, et al. Efficacy and safety of etanercept in moderate-to-severe asthma: a randomised, controlled trial. Eur Respir J 2011;37:1352-1359.
-
(2011)
Eur Respir J
, vol.37
, pp. 1352-1359
-
-
Holgate, S.T.1
Noonan, M.2
Chanez, P.3
-
108
-
-
33749438560
-
The effects of a monoclonal antibody directed against tumor necrosis factor-alpha in asthma
-
Erin EM, Leaker BR, Nicholson GC, et al. The effects of a monoclonal antibody directed against tumor necrosis factor-alpha in asthma. Am J Respir Crit Care Med 2006;174:753-762.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 753-762
-
-
Erin, E.M.1
Leaker, B.R.2
Nicholson, G.C.3
-
109
-
-
62549084077
-
A randomized, double- blind, placebo-controlled study of tumor necrosis factoralpha blockade in severe persistent asthma
-
Wenzel SE, Barnes PJ, Bleecker ER, et al. A randomized, double- blind, placebo-controlled study of tumor necrosis factoralpha blockade in severe persistent asthma. Am J Respir Crit Care Med 2009;179:549-558.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 549-558
-
-
Wenzel, S.E.1
Barnes, P.J.2
Bleecker, E.R.3
-
110
-
-
0034995872
-
Efficacy of soluble IL-4 receptor for the treatment of adults with asthma
-
Borish LC, Nelson HS, Corren J, et al. Efficacy of soluble IL-4 receptor for the treatment of adults with asthma. J Allergy Clin Immunol 2001;107:963-970.
-
(2001)
J Allergy Clin Immunol
, vol.107
, pp. 963-970
-
-
Borish, L.C.1
Nelson, H.S.2
Corren, J.3
-
111
-
-
0036379740
-
Preclinical efficacy and safety of pascolizumab (SB 240683): A humanized anti-interleukin-4 antibody with therapeutic potential in asthma
-
Hart TK, Blackburn MN, Brigham-Burke M, et al. Preclinical efficacy and safety of pascolizumab (SB 240683): a humanized anti-interleukin-4 antibody with therapeutic potential in asthma. Clin Exp Immunol 2002;130:93-100.
-
(2002)
Clin Exp Immunol
, vol.130
, pp. 93-100
-
-
Hart, T.K.1
Blackburn, M.N.2
Brigham-Burke, M.3
-
112
-
-
35348909044
-
Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: Results of two phase 2a studies
-
Wenzel S, Wilbraham D, Fuller R, Getz EB, Longphre M. Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies. Lancet 2007;370:1422-1431.
-
(2007)
Lancet
, vol.370
, pp. 1422-1431
-
-
Wenzel, S.1
Wilbraham, D.2
Fuller, R.3
Getz, E.B.4
Longphre, M.5
-
113
-
-
77953039047
-
A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthma
-
Corren J, Busse W, Meltzer EO, et al. A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthma. Am J Respir Crit Care Med 2010;181:788-796.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 788-796
-
-
Corren, J.1
Busse, W.2
Meltzer, E.O.3
-
114
-
-
57349179165
-
Daclizumab improves asthma control in patients with moderate to severe persistent asthma: A randomized, controlled trial
-
Busse WW, Israel E, Nelson HS, et al. Daclizumab improves asthma control in patients with moderate to severe persistent asthma: a randomized, controlled trial. Am J Respir Crit Care Med 2008;178:1002-1008.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 1002-1008
-
-
Busse, W.W.1
Israel, E.2
Nelson, H.S.3
-
115
-
-
33646858992
-
Inhibition of SCF attenuates peribronchial remodeling in chronic cockroach allergeninduced asthma
-
Berlin AA, Hogaboam CM, Lukacs NW. Inhibition of SCF attenuates peribronchial remodeling in chronic cockroach allergeninduced asthma. Lab Invest 2006;86:557-565.
-
(2006)
Lab Invest
, vol.86
, pp. 557-565
-
-
Berlin, A.A.1
Hogaboam, C.M.2
Lukacs, N.W.3
-
116
-
-
67650314629
-
Masitinib, a c-kit/ PDGF receptor tyrosine kinase inhibitor, improves disease control in severe corticosteroid-dependent asthmatics
-
Humbert M, de Blay F, Garcia G, et al. Masitinib, a c-kit/ PDGF receptor tyrosine kinase inhibitor, improves disease control in severe corticosteroid-dependent asthmatics. Allergy 2009;64:1194-1201.
-
(2009)
Allergy
, vol.64
, pp. 1194-1201
-
-
Humbert, M.1
de Blay, F.2
Garcia, G.3
-
117
-
-
0034458523
-
Synergistic action of endothelin (ET)-1 on the activation of bronchial fibroblast isolated from normal and asthmatic subjects
-
Dube J, Chakir J, Dube C, Grimard Y, Laviolette M, Boulet LP. Synergistic action of endothelin (ET)-1 on the activation of bronchial fibroblast isolated from normal and asthmatic subjects. Int J Exp Pathol 2000;81:429-437.
-
(2000)
Int J Exp Pathol
, vol.81
, pp. 429-437
-
-
Dube, J.1
Chakir, J.2
Dube, C.3
Grimard, Y.4
Laviolette, M.5
Boulet, L.P.6
-
118
-
-
34249702827
-
ETB receptor polymorphism is associated with airway obstruction
-
Taille C, Guenegou A, Almolki A, et al. ETB receptor polymorphism is associated with airway obstruction. BMC Pulm Med 2007;7:5.
-
(2007)
BMC Pulm Med
, vol.7
, pp. 5
-
-
Taille, C.1
Guenegou, A.2
Almolki, A.3
-
119
-
-
38549110631
-
Polymorphisms in the endothelin-1 (EDN1) are associated with asthma in two populations
-
http://www.kjim.or.kr
-
Zhu G, Carlsen K, Carlsen KH, et al. Polymorphisms in the endothelin-1 (EDN1) are associated with asthma in two populations. Genes Immun 2008;9:23-29. http://dx.doi.org/10.3904/kjim.2011.26.4.367 http://www.kjim.or.kr
-
(2008)
Genes Immun
, vol.9
, pp. 23-29
-
-
Zhu, G.1
Carlsen, K.2
Carlsen, K.H.3
-
120
-
-
37549041957
-
Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma
-
Trian T, Benard G, Begueret H, et al. Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma. J Exp Med 2007;204:3173-3181.
-
(2007)
J Exp Med
, vol.204
, pp. 3173-3181
-
-
Trian, T.1
Benard, G.2
Begueret, H.3
-
121
-
-
33846804393
-
Simvastatin does not exhibit therapeutic antiinf lammatory effects in asthma
-
Menzies D, Nair A, Meldrum KT, Fleming D, Barnes M, Lipworth BJ. Simvastatin does not exhibit therapeutic antiinf lammatory effects in asthma. J Allergy Clin Immunol 2007;119:328-335.
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 328-335
-
-
Menzies, D.1
Nair, A.2
Meldrum, K.T.3
Fleming, D.4
Barnes, M.5
Lipworth, B.J.6
-
122
-
-
57149101949
-
Effects of atorvastatin added to inhaled corticosteroids on lung function and sputum cell counts in atopic asthma
-
Hothersall EJ, Chaudhuri R, McSharry C, et al. Effects of atorvastatin added to inhaled corticosteroids on lung function and sputum cell counts in atopic asthma. Thorax 2008;63:1070-1075.
-
(2008)
Thorax
, vol.63
, pp. 1070-1075
-
-
Hothersall, E.J.1
Chaudhuri, R.2
McSharry, C.3
-
123
-
-
6444219538
-
Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs
-
Danek CJ, Lombard CM, Dungworth DL, et al. Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs. J Appl Physiol 2004;97:1946-1953.
-
(2004)
J Appl Physiol
, vol.97
, pp. 1946-1953
-
-
Danek, C.J.1
Lombard, C.M.2
Dungworth, D.L.3
-
124
-
-
21844445318
-
A prospective feasibility study of bronchial thermoplasty in the human airway
-
Miller JD, Cox G, Vincic L, Lombard CM, Loomas BE, Danek CJ. A prospective feasibility study of bronchial thermoplasty in the human airway. Chest 2005;127:1999-2006.
-
(2005)
Chest
, vol.127
, pp. 1999-2006
-
-
Miller, J.D.1
Cox, G.2
Vincic, L.3
Lombard, C.M.4
Loomas, B.E.5
Danek, C.J.6
-
125
-
-
33646242990
-
Bronchial thermoplasty for asthma
-
Cox G, Miller JD, McWilliams A, Fitzgerald JM, Lam S. Bronchial thermoplasty for asthma. Am J Respir Crit Care Med 2006;173:965-969.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 965-969
-
-
Cox, G.1
Miller, J.D.2
McWilliams, A.3
Fitzgerald, J.M.4
Lam, S.5
-
126
-
-
34047099762
-
Asthma control during the year after bronchial thermoplasty
-
Cox G, Thomson NC, Rubin AS, et al. Asthma control during the year after bronchial thermoplasty. N Engl J Med 2007;356:1327-1337.
-
(2007)
N Engl J Med
, vol.356
, pp. 1327-1337
-
-
Cox, G.1
Thomson, N.C.2
Rubin, A.S.3
-
127
-
-
74949090750
-
Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: A multicenter, randomized, double-blind, sham-controlled clinical trial
-
Castro M, Rubin AS, Laviolette M, et al. Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter, randomized, double-blind, sham-controlled clinical trial. Am J Respir Crit Care Med 2010;181:116-124.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 116-124
-
-
Castro, M.1
Rubin, A.S.2
Laviolette, M.3
-
128
-
-
79959771521
-
Persistence of effectiveness of bronchial thermoplasty in patients with severe asthma
-
Castro M, Rubin A, Laviolette M, et al. Persistence of effectiveness of bronchial thermoplasty in patients with severe asthma. Ann Allergy Asthma Immunol 2011;107:65-70.
-
(2011)
Ann Allergy Asthma Immunol
, vol.107
, pp. 65-70
-
-
Castro, M.1
Rubin, A.2
Laviolette, M.3
-
129
-
-
79751533768
-
Long-term (5 year) safety of bronchial thermoplasty: Asthma Intervention Research (AIR) trial
-
Thomson NC, Rubin AS, Niven RM, et al. Long-term (5 year) safety of bronchial thermoplasty: Asthma Intervention Research (AIR) trial. BMC Pulm Med 2011;11:8.
-
(2011)
BMC Pulm Med
, vol.11
, pp. 8
-
-
Thomson, N.C.1
Rubin, A.S.2
Niven, R.M.3
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