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Volumn 20, Issue 17, 2013, Pages 2212-2225

Potential use of polymeric nanoparticles for drug delivery across the blood-brain barrier

Author keywords

Blood brain barrier; Brain targeting; Drug delivery; Gene therapy; Lysosomal storage disorders; Nanoparticles; PLGA

Indexed keywords

CEREBROSIDE SULFATASE; GLYCOPEPTIDE; LEUPRORELIN; LIPOSOME; NANOPARTICLE; POLYGLACTIN; PROSTATE SPECIFIC MEMBRANE ANTIGEN;

EID: 84877953644     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/0929867311320170006     Document Type: Article
Times cited : (122)

References (177)
  • 1
    • 84868124431 scopus 로고    scopus 로고
    • Nanotechnology in therapeutics: A focus on nanoparticles as a drug delivery system
    • Bamrungsap, S.; Zhao, Z.; Chen, T.; Wang, L.; Li, C.; Fu, T.; Tan, W. Nanotechnology in therapeutics: A focus on nanoparticles as a drug delivery system. Nanomedicine, 2012, 7(8), 1253-1271.
    • (2012) Nanomedicine , vol.7 , Issue.8 , pp. 1253-1271
    • Bamrungsap, S.1    Zhao, Z.2    Chen, T.3    Wang, L.4    Li, C.5    Fu, T.6    Tan, W.7
  • 2
    • 84855824016 scopus 로고    scopus 로고
    • Nanoparticles a boon to drug delivery, therapeutics, diagnostics and imaging
    • Parveen, S.; Misra, R.; Sahoo, S.K. Nanoparticles: A boon to drug delivery, therapeutics, diagnostics and imaging. Nanomedicine, 2012, 8(2), 147-166.
    • (2012) Nanomedicine , vol.8 , Issue.2 , pp. 147-166
    • Parveen, S.1    Misra, R.2    Sahoo, S.K.3
  • 3
    • 47049099053 scopus 로고    scopus 로고
    • Multifunctional nanoparticles-properties and prospects for their use in human medicine
    • Sanvicens, N.; Marco, M.P.; Multifunctional nanoparticles-properties and prospects for their use in human medicine. Trends Biotechnol., 2008, 26(8), 425-433.
    • (2008) Trends Biotechnol. , vol.26 , Issue.8 , pp. 425-433
    • Sanvicens, N.1    Marco, M.P.2
  • 4
    • 33749820952 scopus 로고    scopus 로고
    • The emerging nanomedicine landscape
    • DOI 10.1038/nbt1006-1211, PII NBT10061211
    • Wagner, V.; Dullaart, A.; Bock, A.K.; Zweck, A.; The emerging nanomedicine landscape. Nat. Biotechnol., 2006, 24(10), 1211-1217. (Pubitemid 44564760)
    • (2006) Nature Biotechnology , vol.24 , Issue.10 , pp. 1211-1217
    • Wagner, V.1    Dullaart, A.2    Bock, A.-K.3    Zweck, A.4
  • 5
    • 0032580445 scopus 로고    scopus 로고
    • Development of liposomal anthracyclines: From basics to clinical applications
    • DOI 10.1016/S0168-3659(97)00261-7, PII S0168365997002617
    • Gabizon, A.; Goren, D.; Cohen, R.; Barenholz, Y.; Development of liposomal anthracyclines: From basics to clinical applications. J. Control Release, 1998, 53(1-3), 275-279. (Pubitemid 28218710)
    • (1998) Journal of Controlled Release , vol.53 , Issue.1-3 , pp. 275-279
    • Gabizon, A.1    Goren, D.2    Cohen, R.3    Barenholz, Y.4
  • 7
    • 11144310022 scopus 로고    scopus 로고
    • Advantages of liposomal delivery systems for anthracyclines
    • DOI 10.1053/j.seminoncol.2004.08.001, PII S0093775404003781
    • Allen, T.M.; Martin, F.J. Advantages of liposomal delivery systems for anthracyclines. Semin. Oncol., 2004, 3(6 Suppl 13), 5-15. (Pubitemid 40023239)
    • (2004) Seminars in Oncology , vol.31 , Issue.SUPPL. 13 , pp. 5-15
    • Allen, T.M.1    Martin, F.J.2
  • 8
    • 0025953652 scopus 로고
    • Liposomal amphotericin B (AmBisome): Safety data from a phase II/III clinical trial
    • Meunier, F.; Prentice, H. G.; Ringden, O. Liposomal amphotericin B (AmBisome): Safety data from a phase II/III clinical trial. J. Antimicrob. Chemother., 1991, 28 Suppl B 83-91.
    • (1991) J. Antimicrob. Chemother. , vol.28 , Issue.SUPPL. B , pp. 83-91
    • Meunier, F.1    Prentice, H.G.2    Ringden, O.3
  • 9
    • 79959784406 scopus 로고    scopus 로고
    • Nanoparticle therapeutics: FDA approval, clinical trials, regulatory pathways, and case study
    • Eifler, A.C.; Thaxton, C.S. Nanoparticle therapeutics: FDA approval, clinical trials, regulatory pathways, and case study. Methods Mol. Biol., 2011, 726, 325-338.
    • (2011) Methods Mol. Biol. , vol.726 , pp. 325-338
    • Eifler, A.C.1    Thaxton, C.S.2
  • 10
    • 42649132499 scopus 로고    scopus 로고
    • Protein nanoparticles as drug carriers in clinical medicine
    • Hawkins, M. J.; Soon-Shiong, P.; Desai, N. Protein nanoparticles as drug carriers in clinical medicine. Adv. Drug. Deliv. Rev., 2008, 60(8), 876-885.
    • (2008) Adv. Drug. Deliv. Rev. , vol.60 , Issue.8 , pp. 876-885
    • Hawkins, M.J.1    Soon-Shiong, P.2    Desai, N.3
  • 11
    • 33745461665 scopus 로고    scopus 로고
    • Bringing nanomedicines to market: regulatory challenges, opportunities, and uncertainties
    • DOI 10.1016/j.nano.2006.04.005, PII S1549963406000451
    • Nijhara, R.; Balakrishnan, K. Bringing nanomedicines to market: Regulatory challenges, opportunities, and uncertainties. Nanomedicine, 2006, 2(2), 127-136. (Pubitemid 43956611)
    • (2006) Nanomedicine: Nanotechnology, Biology, and Medicine , vol.2 , Issue.2 , pp. 127-136
    • Nijhara, R.1    Balakrishnan, K.2
  • 13
    • 0141927263 scopus 로고    scopus 로고
    • Stealth liposomes and long circulating nanoparticles: Critical issues in pharmacokinetics, opsonization and protein-binding properties
    • DOI 10.1016/S0163-7827(03)00033-X
    • Moghimi, S. M.; Szebeni, J. Stealth liposomes and long circulating nanoparticles: Critical issues in pharmacokinetics, opsonization and protein-binding properties. Prog. Lipid. Res., 2003, 42(6), 463-478. (Pubitemid 37237636)
    • (2003) Progress in Lipid Research , vol.42 , Issue.6 , pp. 463-478
    • Moghimi, S.M.1    Szebeni, J.2
  • 14
    • 80054741757 scopus 로고    scopus 로고
    • Self-assembled targeted nanoparticles: Evolution of technologies and bench to bedside translation
    • Shi, J.; Xiao, Z.; Kamaly, N.; Farokhzad, O.C. Self-assembled targeted nanoparticles: Evolution of technologies and bench to bedside translation. Acc. Chem. Res., 2011, 44(10), 1123-1134.
    • (2011) Acc. Chem. Res. , vol.44 , Issue.10 , pp. 1123-1134
    • Shi, J.1    Xiao, Z.2    Kamaly, N.3    Farokhzad, O.C.4
  • 16
    • 22244492667 scopus 로고    scopus 로고
    • Characterization of degradation behavior for PLGA in various pH condition by simple liquid chromatography method
    • Yoo, J.Y.; Kim, J.M.; Seo, K.S.; Jeong, Y.K.; Lee, H.B.; Khang, G. Characterization of degradation behavior for PLGA in various pH condition by simple liquid chromatography method. Biomed. Mater. Eng., 2005, 15(4), 279-288. (Pubitemid 40991530)
    • (2005) Bio-Medical Materials and Engineering , vol.15 , Issue.4 , pp. 279-288
    • Je, Y.Y.1    Jong, M.K.2    Kwang, S.S.3    Yong, K.J.4    Hai, B.L.5    Khang, G.6
  • 17
    • 70450221930 scopus 로고    scopus 로고
    • Biodegradable polymeric nanoparticles based drug delivery systems
    • Kumari, A.; Yadav, S.K.; Yadav, S.C. Biodegradable polymeric nanoparticles based drug delivery systems. Colloids Surf. B. Biointerfaces, 2010, 75(1), 1-18.
    • (2010) Colloids Surf. B. Biointerfaces , vol.75 , Issue.1 , pp. 1-18
    • Kumari, A.1    Yadav, S.K.2    Yadav, S.C.3
  • 18
    • 0028564916 scopus 로고
    • Biodegradation of PLA/GA polymers: Increasing complexity
    • Vert, M.; Mauduit, J.; Li, S. Biodegradation of PLA/GA polymers: Increasing complexity. Biomaterials, 1994, 15(15), 1209-1213.
    • (1994) Biomaterials , vol.15 , Issue.15 , pp. 1209-1213
    • Vert, M.1    Mauduit, J.2    Li, S.3
  • 19
    • 0017536083 scopus 로고
    • Degradation rates of oral resorbable implants (polylactates and polyglycolates): Rate modification with changes in PLA/PGA copolymer ratios
    • DOI 10.1002/jbm.820110507
    • Miller, R. A.; Brady, J. M.; Cutright, D. E; Degradation rates of oral resorbable implants (polylactates and polyglycolates): Rate modification with changes in PLA/PGA copolymer ratios. J. Biomed. Mater. Res., 1977, 11(5), 711-719. (Pubitemid 8159588)
    • (1977) Journal of Biomedical Materials Research , vol.11 , Issue.5 , pp. 711-719
    • Miller, R.A.1    Brady, J.M.2    Cutright, D.E.3
  • 20
    • 0029969221 scopus 로고    scopus 로고
    • In vitro degradation of nanospheres from poly(D,L-lactides) of different molecular weights and polydispersities
    • DOI 10.1016/0378-5173(95)04258-X
    • Belbella, A.; Vauthier, C.; Fessi, H.; Devissaguet, J. P.; Puisieux, F. In vitro degradation of nanospheres from poly(D,L-lactides) of different molecular weights and polydispersity. Int. J. Pharm., 1996, 129(1-2), 95-102. (Pubitemid 26097979)
    • (1996) International Journal of Pharmaceutics , vol.129 , Issue.1-2 , pp. 95-102
    • Belbella, A.1    Vauthier, C.2    Fessi, H.3    Devissaguet, J.-P.4    Puisieux, F.5
  • 21
    • 0030298086 scopus 로고    scopus 로고
    • Stability study of nanoparticles of poly(ε-caprolactone), poly(D,L-lactide) and poly(D,L-lactide-co-glycolide)
    • DOI 10.1016/0142-9612(96)00049-X
    • Lemoine, D.; Francois, C.; Kedzierewicz, F.; Preat, V.; Hoffman, M.; Maincent, P. Stability study of nanoparticles of poly(epsiloncaprolactone), poly(D,L-lactide) and poly(D,L-lactide-coglycolide). Biomaterials, 1996, 17(22), 2191-2197. (Pubitemid 26364773)
    • (1996) Biomaterials , vol.17 , Issue.22 , pp. 2191-2197
    • Lemoine, D.1    Francois, C.2    Kedzierewicz, F.3    Preat, V.4    Hoffman, M.5    Maincent, P.6
  • 22
    • 34147150618 scopus 로고    scopus 로고
    • Estradiol loaded PLGA nanoparticles for oral administration: Effect of polymer molecular weight and copolymer composition on release behavior in vitro and in vivo
    • DOI 10.1016/j.jconrel.2007.01.016, PII S0168365907000661
    • Mittal, G.; Sahana, D.K.; Bhardwaj, V.; Ravi Kumar, M.N. Estradiol loaded PLGA nanoparticles for oral administration: Effect of polymer molecular weight and copolymer composition on release behavior in vitro and in vivo. J. Control Release, 2007, 119(1), 77-85. (Pubitemid 46561546)
    • (2007) Journal of Controlled Release , vol.119 , Issue.1 , pp. 77-85
    • Mittal, G.1    Sahana, D.K.2    Bhardwaj, V.3    Ravi Kumar, M.N.V.4
  • 23
    • 0034036366 scopus 로고    scopus 로고
    • Influence of particle size and dissolution conditions on the degradation properties of polylactide-co-glycolide particles
    • DOI 10.1016/S0142-9612(00)00040-5, PII S0142961200000405
    • Dunne, M.; Corrigan, I.; Ramtoola, Z. Influence of particle size and dissolution conditions on the degradation properties of polylactideco-glycolide particles. Biomaterials, 2000, 21(16), 1659-1668. (Pubitemid 30347308)
    • (2000) Biomaterials , vol.21 , Issue.16 , pp. 1659-1668
    • Dunne, M.1    Corrigan, O.I.2    Ramtoola, Z.3
  • 24
    • 0141853257 scopus 로고    scopus 로고
    • Polymer degradation and in vitro release of a model protein from poly(D,L-lactide-co-glycolide) nano- and microparticles
    • DOI 10.1016/S0168-3659(03)00328-6
    • Panyam, J.; Dali, M.M.; Sahoo, S.K.; Ma, W.; Chakravarthi, S.S.; Amidon, G.L.; Levy, R.J.; Labhasetwar, V. Polymer degradation and in vitro release of a model protein from poly(D,L-lactide-coglycolide) nano-and microparticles. J. Control Release, 2003, 92(1-2), 173-187. (Pubitemid 37130131)
    • (2003) Journal of Controlled Release , vol.92 , Issue.1-2 , pp. 173-187
    • Panyam, J.1    Dali, M.M.2    Sahoo, S.K.3    Ma, W.4    Chakravarthi, S.S.5    Amidon, G.L.6    Levy, R.J.7    Labhasetwar, V.8
  • 25
    • 51049092308 scopus 로고    scopus 로고
    • Factors affecting the clearance and biodistribution of polymeric nanoparticles
    • Alexis, F.; Pridgen, E.; Molnar, L.K.; Farokhzad, O.C. Factors affecting the clearance and biodistribution of polymeric nanoparticles. Mol. Pharm., 2008, 5(4), 505-515.
    • (2008) Mol. Pharm. , vol.5 , Issue.4 , pp. 505-515
    • Alexis, F.1    Pridgen, E.2    Molnar, L.K.3    Farokhzad, O.C.4
  • 26
    • 37849039288 scopus 로고    scopus 로고
    • Nanomedicine: Sizing up targets with nanoparticles
    • Minchin, R. Nanomedicine: Sizing up targets with nanoparticles. Nat. Nanotechnol., 2008, 3(1), 12-13.
    • (2008) Nat. Nanotechnol. , vol.3 , Issue.1 , pp. 12-13
    • Minchin, R.1
  • 27
    • 82255179274 scopus 로고    scopus 로고
    • Effect of size on the biodistribution and blood clearance of etoposide-loaded plga nanoparticles. PDA
    • Yadav, K.S.; Chuttani, K.; Mishra, A.K.; Sawant, K.K. Effect of Size on the Biodistribution and Blood Clearance of Etoposide-Loaded PLGA Nanoparticles. PDA. J. Pharm. Sci. Technol., 2011, 65(2), 131-139.
    • (2011) J. Pharm. Sci. Technol. , vol.65 , Issue.2 , pp. 131-139
    • Yadav, K.S.1    Chuttani, K.2    Mishra, A.K.3    Sawant, K.K.4
  • 28
    • 34547910668 scopus 로고    scopus 로고
    • Time-dependent changes in opsonin amount associated on nanoparticles alter their hepatic uptake characteristics
    • DOI 10.1016/j.ijpharm.2007.04.036, PII S0378517307003651
    • Nagayama, S.; Ogawara, K.; Fukuoka, Y.; Higaki, K.; Kimura, T. Time-dependent changes in opsonin amount associated on nanoparticles alter their hepatic uptake characteristics. Int. J. Pharm., 2007, 342(1-2), 215-221. (Pubitemid 47259322)
    • (2007) International Journal of Pharmaceutics , vol.342 , Issue.1-2 , pp. 215-221
    • Nagayama, S.1    Ogawara, K.-i.2    Fukuoka, Y.3    Higaki, K.4    Kimura, T.5
  • 30
    • 84858616151 scopus 로고    scopus 로고
    • Physico-chemical parameters that govern nanoparticles fate also dictate rules for their molecular evolution
    • Dufort, S.; Sancey, L.; Coll, J.L.; Physico-chemical parameters that govern nanoparticles fate also dictate rules for their molecular evolution. Adv. Drug. Deliv. Rev., 2012, 64(2), 179-189.
    • (2012) Adv. Drug. Deliv. Rev. , vol.64 , Issue.2 , pp. 179-189
    • Dufort, S.1    Sancey, L.2    Coll, J.L.3
  • 31
    • 28844488494 scopus 로고    scopus 로고
    • Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles
    • DOI 10.1016/j.ijpharm.2005.10.010, PII S037851730500668X
    • Owens, D.E. 3rd; Peppas, N.A. Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles. Int. J. Pharm., 2006, 307(1), 93-102. (Pubitemid 41773257)
    • (2006) International Journal of Pharmaceutics , vol.307 , Issue.1 , pp. 93-102
    • Owens III, D.E.1    Peppas, N.A.2
  • 32
    • 11844282159 scopus 로고    scopus 로고
    • Interaction of PLGA nanoparticles with human blood constituents
    • DOI 10.1016/j.colsurfb.2004.05.007, PII S0927776504001389
    • Kim, D.; El-Shall, H.; Dennis, D.; Morey, T. Interaction of PLGA nanoparticles with human blood constituents. Colloids Surf. B. Biointerfaces, 2005, 40(2), 83-91. (Pubitemid 40092448)
    • (2005) Colloids and Surfaces B: Biointerfaces , vol.40 , Issue.2 , pp. 83-91
    • Kim, D.1    El-Shall, H.2    Dennis, D.3    Morey, T.4
  • 33
    • 78650524261 scopus 로고    scopus 로고
    • Development of peptide and protein nanotherapeutics by nanoencapsulation and nanobioconjugation
    • Yadav, S.C.; Kumari, A.; Yadav, R. Development of peptide and protein nanotherapeutics by nanoencapsulation and nanobioconjugation. Peptides, 2011, 32(1), 173-187.
    • (2011) Peptides , vol.32 , Issue.1 , pp. 173-187
    • Yadav, S.C.1    Kumari, A.2    Yadav, R.3
  • 34
    • 34547202478 scopus 로고    scopus 로고
    • Coupling of biotin-(poly(ethylene glycol))amine to poly(D,L-lactide-co- glycolide) nanoparticles for versatile surface modification
    • DOI 10.1021/bc060342f
    • Weiss, B.; Schneider, M.; Muys, L.; Taetz, S.; Neumann, D.; Schaefer, U.F.; Lehr, C.M. Coupling of biotin-(poly(ethylene glycol)) amine to poly(D,L-lactide-co-glycolide) nanoparticles for versatile surface modification. Bioconjug. Chem., 2007, 18(4), 1087-1094. (Pubitemid 47122628)
    • (2007) Bioconjugate Chemistry , vol.18 , Issue.4 , pp. 1087-1094
    • Weiss, B.1    Schneider, M.2    Muys, L.3    Taetz, S.4    Neumann, D.5    Schaefer, U.F.6    Lehr, C.-M.7
  • 35
    • 0031021149 scopus 로고    scopus 로고
    • Sterically stabilized anti-HER2 immunoliposomes: Design and targeting to human breast cancer cells in vitro
    • DOI 10.1021/bi962148u
    • Kirpotin, D.; Park, J.W.; Hong, K.; Zalipsky, S.; Li, W.L.; Carter, P.; Benz, C.C.; Papahadjopoulos, D. Sterically stabilized anti-HER2 immunoliposomes: Design and targeting to human breast cancer cells in vitro. Biochemistry,1997, 36(1), 66-75. (Pubitemid 27024679)
    • (1997) Biochemistry , vol.36 , Issue.1 , pp. 66-75
    • Kirpotin, D.1    Park, J.W.2    Hong, K.3    Zalipsky, S.4    Li, W.-L.5    Carter, P.6    Benz, C.C.7    Papahadjopoulos, D.8
  • 37
    • 33751253462 scopus 로고    scopus 로고
    • Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach
    • DOI 10.1016/j.jconrel.2006.08.013, PII S0168365906004020
    • des Rieux, A.; Fievez, V.; Garinot, M.; Schneider, Y.J.; Preat, V. Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach. J. Control Release, 2006, 116(1), 1-27. (Pubitemid 44792295)
    • (2006) Journal of Controlled Release , vol.116 , Issue.1 , pp. 1-27
    • Des Rieux, A.1    Fievez, V.2    Garinot, M.3    Schneider, Y.-J.4    Preat, V.5
  • 38
    • 34247516346 scopus 로고    scopus 로고
    • Poly(D,L-lactide-co-glycolide acid) nanoparticles for DNA delivery: Waiving preparation complexity and increasing efficiency
    • DOI 10.1002/bip.20697
    • Gvili, K.; Benny, O.; Danino, D.; Machluf, M. Poly(D,L-lactideco- glycolide acid) nanoparticles for DNA delivery: Waiving preparation complexity and increasing efficiency. Biopolymers, 2007, 85(5-6), 379-391. (Pubitemid 46649820)
    • (2007) Biopolymers , vol.85 , Issue.5-6 , pp. 379-391
    • Gvili, K.1    Benny, O.2    Danino, D.3    Machluf, M.4
  • 41
    • 78650042168 scopus 로고    scopus 로고
    • Lectin anchored PLGA nanoparticles for oral mucosal immunization against hepatitis
    • Mishra, N.; Tiwari, S.; Vaidya, B.; Agrawal, G.P.; Vyas, S.P.; Lectin anchored PLGA nanoparticles for oral mucosal immunization against hepatitis. B. J. Drug. Target, 2011, 19(1), 67-78.
    • (2011) B. J. Drug. Target , vol.19 , Issue.1 , pp. 67-78
    • Mishra, N.1    Tiwari, S.2    Vaidya, B.3    Agrawal, G.P.4    Vyas, S.P.5
  • 42
    • 84858115907 scopus 로고    scopus 로고
    • Biodegradable Nanoparticles as Vaccine. Adjuvants and Delivery Systems: Regulation of Immune Responses by Nanoparticle-Based Vaccine
    • Akagi, T.; Baba, M.; Akashi, M. Biodegradable Nanoparticles as Vaccine. Adjuvants and Delivery Systems: Regulation of Immune Responses by Nanoparticle-Based Vaccine. Adv. Polym. Sci., 2011, 247,31-64.
    • (2011) Adv. Polym. Sci. , vol.247 , pp. 31-64
    • Akagi, T.1    Baba, M.2    Akashi, M.3
  • 43
    • 39749086433 scopus 로고    scopus 로고
    • Polymeric nanoparticles for the drug delivery to the central nervous system
    • DOI 10.1517/17425247.5.2.155
    • Tosi, G.; Costantino, L.; Ruozi, B.; Forni, F.; Vandelli, M.A. Polymeric nanoparticles for the drug delivery to the central nervous system. Expert Opin. Drug. Deliv., 2008, 5(2), 155-174. (Pubitemid 351308309)
    • (2008) Expert Opinion on Drug Delivery , vol.5 , Issue.2 , pp. 155-174
    • Tosi, G.1    Costantino, L.2    Ruozi, B.3    Forni, F.4    Vandelli, M.A.5
  • 45
    • 79955583887 scopus 로고    scopus 로고
    • Investigation on mechanisms of glycopeptide nanoparticles for drug delivery across the blood-brain barrier
    • Tosi, G.; Fano, R. A.; Bondioli, L.; Badiali, L.; Benassi, R.; Rivasi, F.; Ruozi, B.; Forni, F.; Vandelli, M.A. Investigation on mechanisms of glycopeptide nanoparticles for drug delivery across the blood-brain barrier. Nanomedicine, 2011, 6 (3), 423-436.
    • (2011) Nanomedicine , vol.6 , Issue.3 , pp. 423-436
    • Tosi, G.1    Fano, R.A.2    Bondioli, L.3    Badiali, L.4    Benassi, R.5    Rivasi, F.6    Ruozi, B.7    Forni, F.8    Vandelli, M.A.9
  • 47
    • 84861472603 scopus 로고    scopus 로고
    • The Bridge between nanotechnology and neuroscience: Neuro-Nanomedicine
    • Tosi, G.; Ruozi, B.; Belletti, D.; Badiali, L.; Vandelli, M.A.; The Bridge between nanotechnology and neuroscience: Neuro-Nanomedicine. J. Neurosci., 2012, 2(1), 20-26.
    • (2012) J. Neurosci. , vol.2 , Issue.1 , pp. 20-26
    • Tosi, G.1    Ruozi, B.2    Belletti, D.3    Badiali, L.4    Vandelli, M.A.5
  • 48
    • 84861476589 scopus 로고    scopus 로고
    • Advances and perspectives for Central Nervous System drug delivery: The interface between nanotechnology and neuroscience
    • Tosi, G.; Muresanu, D.F.; Sharma, A. Advances and perspectives for Central Nervous System drug delivery: The interface between nanotechnology and neuroscience. J. Neurosci., 2012, 2(1), 1-4.
    • (2012) J. Neurosci. , vol.2 , Issue.1 , pp. 1-4
    • Tosi, G.1    Muresanu, D.F.2    Sharma, A.3
  • 49
    • 84868127411 scopus 로고    scopus 로고
    • Nanomedicine the future for advancing medicine and neuroscience
    • Tosi, G.; Ruozi, B.; Belletti, D. Nanomedicine: The future for advancing medicine and neuroscience. Nanomedicine, 2012, 7(8), 1113-1116.
    • (2012) Nanomedicine , vol.7 , Issue.8 , pp. 1113-1116
    • Tosi, G.1    Ruozi, B.2    Belletti, D.3
  • 51
    • 34249894977 scopus 로고    scopus 로고
    • Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody
    • DOI 10.1016/j.jconrel.2007.03.012, PII S0168365907001472
    • Kocbek, P.; Obermajer, N.; Cegnar, M.; Kos, J.; Kristl, J. Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody. J. Control. Release, 2007, 120(1-2), 18-26. (Pubitemid 46874614)
    • (2007) Journal of Controlled Release , vol.120 , Issue.1-2 , pp. 18-26
    • Kocbek, P.1    Obermajer, N.2    Cegnar, M.3    Kos, J.4    Kristl, J.5
  • 52
  • 53
    • 68949103744 scopus 로고    scopus 로고
    • Drug nanocarriers and functional nanoparticles: Applications in cancer therapy
    • Thierry, B. Drug nanocarriers and functional nanoparticles: Applications in cancer therapy. Curr. Drug. Deliv., 2009, 6(4), 391-403.
    • (2009) Curr. Drug. Deliv. , vol.6 , Issue.4 , pp. 391-403
    • Thierry, B.1
  • 54
    • 79953035086 scopus 로고    scopus 로고
    • PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect
    • Acharya, S.; Sahoo, S.K. PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect. Adv. Drug. Deliv. Rev., 2011, 63(3), 170-183.
    • (2011) Adv. Drug. Deliv. Rev. , vol.63 , Issue.3 , pp. 170-183
    • Acharya, S.1    Sahoo, S.K.2
  • 55
    • 80155194438 scopus 로고    scopus 로고
    • Polylactide-co-glycolide nanoparticles for Control led delivery of anticancer agents
    • Dinarvand, R.; Sepehri, N.; Manoochehri, S.; Rouhani, H.; Atyabi, F. Polylactide-co-glycolide nanoparticles for Control led delivery of anticancer agents. Int. J. Nanomedicine, 2011, 6 877-895.
    • (2011) Int. J. Nanomedicine , vol.6 , pp. 877-895
    • Dinarvand, R.1    Sepehri, N.2    Manoochehri, S.3    Rouhani, H.4    Atyabi, F.5
  • 56
    • 79955648519 scopus 로고    scopus 로고
    • Engineered PLGA nanoparticles: An emerging delivery tool in cancer therapeutics
    • Jain, A.K.; Das, M.; Swarnakar, N.K.; Jain, S. Engineered PLGA nanoparticles: An emerging delivery tool in cancer therapeutics. Crit. Rev. Ther. Drug. Carrier. Syst., 2011, 28(1), 1-45.
    • (2011) Crit. Rev. Ther. Drug. Carrier. Syst. , vol.28 , Issue.1 , pp. 1-45
    • Jain, A.K.1    Das, M.2    Swarnakar, N.K.3    Jain, S.4
  • 57
    • 84870236985 scopus 로고    scopus 로고
    • Anticancer nanomedicine and tumor vascular permeability; Where is the missing link?
    • Taurin, S.; Nehoff, H.; Greish, K. Anticancer nanomedicine and tumor vascular permeability; Where is the missing link? J. Control. Release, 2012, 164(3), 265-275.
    • (2012) J. Control. Release , vol.164 , Issue.3 , pp. 265-275
    • Taurin, S.1    Nehoff, H.2    Greish, K.3
  • 58
    • 33644625226 scopus 로고    scopus 로고
    • G-CSF loaded biodegradable PLGA nanoparticles prepared by a single oil-in-water emulsion method
    • Choi, S.H.; Park, T.G. G-CSF loaded biodegradable PLGA nanoparticles prepared by a single oil-in-water emulsion method. Int. J. Pharm., 2006, 311(1-2), 223-228.
    • (2006) Int. J. Pharm. , vol.311 , Issue.1-2 , pp. 223-228
    • Choi, S.H.1    Park, T.G.2
  • 60
    • 66149145455 scopus 로고    scopus 로고
    • RNA interference of MBD1 in BxPC-3 human pancreatic cancer cells delivered by PLGA-poloxamer nanoparticles
    • Luo, G.; Jin, C.; Long, J.; Fu, D.; Yang, F.; Xu, J.; Yu, X.; Chen, W.; Ni, Q. RNA interference of MBD1 in BxPC-3 human pancreatic cancer cells delivered by PLGA-poloxamer nanoparticles. Cancer. Biol. Ther., 2009, 8(7), 594-598.
    • (2009) Cancer. Biol. Ther. , vol.8 , Issue.7 , pp. 594-598
    • Luo, G.1    Jin, C.2    Long, J.3    Fu, D.4    Yang, F.5    Xu, J.6    Yu, X.7    Chen, W.8    Ni, Q.9
  • 61
    • 67549130802 scopus 로고    scopus 로고
    • Polymeric nanoparticles for sustained down-regulation of annexin A2 inhibit prostate tumor growth
    • Braden, A.R.; Kafka, M.T.; Cunningham, L.; Jones, H.; Vishwanatha, J.K. Polymeric nanoparticles for sustained down-regulation of annexin A2 inhibit prostate tumor growth. J. Nanosci. Nanotechnol., 2009, 9(5), 2856-2865.
    • (2009) J. Nanosci. Nanotechnol. , vol.9 , Issue.5 , pp. 2856-2865
    • Braden, A.R.1    Kafka, M.T.2    Cunningham, L.3    Jones, H.4    Vishwanatha, J.K.5
  • 62
    • 0023443956 scopus 로고
    • The role of calcitonin in the development and treatment of osteoporosis
    • McDermott, M.T.; Kidd, G.S. The role of calcitonin in the development and treatment of osteoporosis. Endocr. Rev., 1987, 8(4), 377-390.
    • (1987) Endocr. Rev. , vol.8 , Issue.4 , pp. 377-390
    • McDermott, M.T.1    Kidd, G.S.2
  • 64
    • 0036108432 scopus 로고    scopus 로고
    • Prolonged anti-inflammatory action of DL-lactide/glycolide copolymer nanospheres containing betamethasone sodium phosphate for an intra-articular delivery system in antigen-induced arthritic rabbit
    • DOI 10.1023/A:1015123024113
    • Horisawa, E.; Hirota, T.; Kawazoe, S.; Yamada, J.; Yamamoto, H.; Takeuchi, H.; Kawashima, Y. Prolonged anti-inflammatory action of DL-lactide/glycolide copolymer nanospheres containing betamethasone sodium phosphate for an intra-articular delivery system in antigen-induced arthritic rabbit. Pharm. Res., 2002, 19(4), 403-410. (Pubitemid 34408936)
    • (2002) Pharmaceutical Research , vol.19 , Issue.4 , pp. 403-410
    • Horisawa, E.1    Hirota, T.2    Kawazoe, S.3    Yamada, J.4    Yamamoto, H.5    Takeuchi, H.6    Kawashima, Y.7
  • 65
    • 25644442467 scopus 로고    scopus 로고
    • Nanoparticles enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats
    • DOI 10.1124/jpet.105.088146
    • Lamprecht, A.; Yamamoto, H.; Takeuchi, H.; Kawashima, Y. Nanoparticles enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats. J. Pharmacol. Exp. Ther., 2005, 315(1), 196-202. (Pubitemid 41380512)
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.315 , Issue.1 , pp. 196-202
    • Lamprecht, A.1    Yamamoto, H.2    Takeuchi, H.3    Kawashima, Y.4
  • 66
    • 23444436529 scopus 로고    scopus 로고
    • Treatment of experimental arthritis with poly(D, L-lactic/glycolic acid) nanoparticles encapsulating betamethasone sodium phosphate
    • DOI 10.1136/ard.2004.030759
    • Higaki, M.; Ishihara, T.; Izumo, N.; Takatsu, M.; Mizushima, Y. Treatment of experimental arthritis with poly(D, L-lactic/glycolic acid) nanoparticles encapsulating betamethasone sodium phosphate. Ann. Rheum. Dis., 2005, 64(8), 1132-1136. (Pubitemid 41113345)
    • (2005) Annals of the Rheumatic Diseases , vol.64 , Issue.8 , pp. 1132-1136
    • Higaki, M.1    Ishihara, T.2    Izumo, N.3    Takatsu, M.4    Mizushima, Y.5
  • 67
    • 59949091205 scopus 로고    scopus 로고
    • Diclofenac-loaded biopolymeric nanosuspensions for ophthalmic application
    • Agnihotri, S.M.; Vavia, P.R. Diclofenac-loaded biopolymeric nanosuspensions for ophthalmic application. Nanomedicine, 2009, 5(1), 90-95.
    • (2009) Nanomedicine , vol.5 , Issue.1 , pp. 90-95
    • Agnihotri, S.M.1    Vavia, P.R.2
  • 68
    • 67349194262 scopus 로고    scopus 로고
    • Effect of polymer viscosity on physicochemical properties and ocular tolerance of FB-loaded PLGA nanospheres
    • Araujo, J.; Vega, E.; Lopes, C.; Egea, M.A.; Garcia, M.L.; Souto, E.B. Effect of polymer viscosity on physicochemical properties and ocular tolerance of FB-loaded PLGA nanospheres. Colloids Surf. B. Biointerfaces, 2009, 72(1), 48-56.
    • (2009) Colloids Surf. B. Biointerfaces , vol.72 , Issue.1 , pp. 48-56
    • Araujo, J.1    Vega, E.2    Lopes, C.3    Egea, M.A.4    Garcia, M.L.5    Souto, E.B.6
  • 69
    • 77956930518 scopus 로고    scopus 로고
    • Development of PEGylated PLGA nanoparticle for controlled and sustained drug delivery in cystic fibrosis
    • Vij, N.; Min, T.; Marasigan, R.; Belcher, C.N.; Mazur, S.; Ding, H.; Yong, K.T.; Roy, I. Development of PEGylated PLGA nanoparticle for controlled and sustained drug delivery in cystic fibrosis. J. Nanobiotechnology, 2010, 8, 22.
    • (2010) J. Nanobiotechnology , vol.8 , pp. 22
    • Vij, N.1    Min, T.2    Marasigan, R.3    Belcher, C.N.4    Mazur, S.5    Ding, H.6    Yong, K.T.7    Roy, I.8
  • 70
    • 52049108266 scopus 로고    scopus 로고
    • Sustained intraspinal delivery of neurotrophic factor encapsulated in biodegradable nanoparticles following contusive spinal cord injury
    • Wang, Y.C.; Wu, Y.T.; Huang, H.Y.; Lin, H.I.; Lo, L.W.; Tzeng, S.F.; Yang, C.S. Sustained intraspinal delivery of neurotrophic factor encapsulated in biodegradable nanoparticles following contusive spinal cord injury. Biomaterials, 2008, 29(34), 4546-4553.
    • (2008) Biomaterials , vol.29 , Issue.34 , pp. 4546-4553
    • Wang, Y.C.1    Wu, Y.T.2    Huang, H.Y.3    Lin, H.I.4    Lo, L.W.5    Tzeng, S.F.6    Yang, C.S.7
  • 71
    • 55349129238 scopus 로고    scopus 로고
    • Targeted delivery of nanoparticles bearing fibroblast growth factor-2 by ultrasonic microbubble destruction for therapeutic arteriogenesis
    • Chappell, J.C.; Song, J.; Burke, C.W.; Klibanov, A.L.; Price, R.J. Targeted delivery of nanoparticles bearing fibroblast growth factor-2 by ultrasonic microbubble destruction for therapeutic arteriogenesis. Small, 2008, 4(10), 1769-1777.
    • (2008) Small , vol.4 , Issue.10 , pp. 1769-1777
    • Chappell, J.C.1    Song, J.2    Burke, C.W.3    Klibanov, A.L.4    Price, R.J.5
  • 74
    • 33747884001 scopus 로고    scopus 로고
    • Biodegradable nanoparticles loaded with insulin-phospholipid complex for oral delivery: Preparation, in vitro characterization and in vivo evaluation
    • DOI 10.1016/j.jconrel.2006.05.013, PII S0168365906002355, Third International Nanomedicine and Drug Delivery Symposium
    • Cui, F.; Shi, K.; Zhang, L.; Tao, A.; Kawashima, Y. Biodegradable nanoparticles loaded with insulin-phospholipid complex for oral delivery: Preparation, in vitro characterization and in vivo evaluation. J. Control. Release, 2006, 114(2), 242-250. (Pubitemid 44291843)
    • (2006) Journal of Controlled Release , vol.114 , Issue.2 , pp. 242-250
    • Cui, F.1    Shi, K.2    Zhang, L.3    Tao, A.4    Kawashima, Y.5
  • 75
    • 36448954697 scopus 로고    scopus 로고
    • Controlled release of insulin from PLGA nanoparticles embedded within PVA hydrogels
    • DOI 10.1007/s10856-007-3010-0, Special Issue: Selected Papers from the 1st Chinese-European Symposium on Biomaterials in Regenerative Medicine, Suzhou, China, April 2006. Guest Editors: Xingdong Zhang and C. James Kirkpatrick
    • Liu, J.; Zhang, S.M.; Chen, P.P.; Cheng, L.; Zhou, W.; Tang, W.X.; Chen, Z.W.; Ke, C.M. Controlled release of insulin from PLGA nanoparticles embedded within PVA hydrogels. J. Mater. Sci. Mater. Med., 2007, 18(11), 2205-2210. (Pubitemid 350167371)
    • (2007) Journal of Materials Science: Materials in Medicine , vol.18 , Issue.11 , pp. 2205-2210
    • Liu, J.1    Zhang, S.M.2    Chen, P.P.3    Cheng, L.4    Zhou, W.5    Tang, W.X.6    Chen, Z.W.7    Ke, C.M.8
  • 76
    • 34247138257 scopus 로고    scopus 로고
    • Poly(D,L-lactide-coglycolide) particles containing gentamicin: Pharmacokinetics and pharmacodynamics in Brucella melitensis-infected mice
    • DOI 10.1128/AAC.00809-06
    • Lecaroz, M.C.; Blanco-Prieto, M.J.; Campanero, M.A.; Salman, H.; Gamazo, C. Poly(D,L-lactide-coglycolide) particles containing gentamicin: Pharmacokinetics and pharmacodynamics in Brucella melitensis-infected mice. Antimicrob. Agents Chemother., 2007, 51(4), 1185-1190. (Pubitemid 46586792)
    • (2007) Antimicrobial Agents and Chemotherapy , vol.51 , Issue.4 , pp. 1185-1190
    • Lecaroz, M.C.1    Blanco-Prieto, M.J.2    Campanero, M.A.3    Salman, H.4    Gamazo, C.5
  • 77
    • 77949917853 scopus 로고    scopus 로고
    • Sparfloxacin-loaded PLGA nanoparticles for sustained ocular drug delivery
    • Gupta, H.; Aqil, M.; Khar, R.K.; Ali, A.; Bhatnagar, A.; Mittal, G. Sparfloxacin-loaded PLGA nanoparticles for sustained ocular drug delivery. Nanomedicine, 2010, 6(2), 324-333.
    • (2010) Nanomedicine , vol.6 , Issue.2 , pp. 324-333
    • Gupta, H.1    Aqil, M.2    Khar, R.K.3    Ali, A.4    Bhatnagar, A.5    Mittal, G.6
  • 78
    • 80053074197 scopus 로고    scopus 로고
    • The loading of labelled antibody-engineered nanoparticles with Indinavir increases its in vitro efficacy against Cryptosporidium parvum
    • Bondioli, L.; Ludovisi, A.; Tosi, G.; Ruozi, B.; Forni, F.; Pozio, E.; Vandelli, M.A.; Gomez-Morales, M.A. The loading of labelled antibody-engineered nanoparticles with Indinavir increases its in vitro efficacy against Cryptosporidium parvum. Parasitology, 2011, 138(11), 1384-1391.
    • (2011) Parasitology , vol.138 , Issue.11 , pp. 1384-1391
    • Bondioli, L.1    Ludovisi, A.2    Tosi, G.3    Ruozi, B.4    Forni, F.5    Pozio, E.6    Vandelli, M.A.7    Gomez-Morales, M.A.8
  • 79
    • 38049178647 scopus 로고    scopus 로고
    • Immunocolloidal targeting of the endocytotic siglec-7 receptor using peripheral attachment of siglec-7 antibodies to poly(lactide-co-glycolide) nanoparticles
    • Scott, C.J.; Marouf, W.M.; Quinn, D.J.; Buick, R.J.; Orr, S.J.; Donnelly, R.F.; McCarron, P.A. Immunocolloidal targeting of the endocytotic siglec-7 receptor using peripheral attachment of siglec-7 antibodies to poly(lactide-co-glycolide) nanoparticles. Pharm. Res., 2008, 2 (1), 135-146.
    • (2008) Pharm. Res. , vol.2 , Issue.1 , pp. 135-146
    • Scott, C.J.1    Marouf, W.M.2    Quinn, D.J.3    Buick, R.J.4    Orr, S.J.5    Donnelly, R.F.6    McCarron, P.A.7
  • 81
    • 70350644891 scopus 로고    scopus 로고
    • Immunomodulatory and anticancer effects of intra-tumoral co-delivery of synthetic lipid A adjuvant and STAT3 inhibitor, JSI-124
    • Molavi, O.; Ma, Z.; Hamdy, S.; Lavasanifar, A.; Samuel, J. Immunomodulatory and anticancer effects of intra-tumoral co-delivery of synthetic lipid A adjuvant and STAT3 inhibitor, JSI-124. Immunopharmacol. Immunotoxicol., 2009, 31(2), 214-221.
    • (2009) Immunopharmacol. Immunotoxicol. , vol.31 , Issue.2 , pp. 214-221
    • Molavi, O.1    Ma, Z.2    Hamdy, S.3    Lavasanifar, A.4    Samuel, J.5
  • 82
    • 77950645416 scopus 로고    scopus 로고
    • Modulation of immune responses through direct activation of Toll-like receptors to T cells
    • Liu, G.; Zhang, L.; Zhao, Y. Modulation of immune responses through direct activation of Toll-like receptors to T cells. Clin. Exp. Immunol., 2010, 160(2), 168-175.
    • (2010) Clin. Exp. Immunol. , vol.160 , Issue.2 , pp. 168-175
    • Liu, G.1    Zhang, L.2    Zhao, Y.3
  • 83
    • 76749130541 scopus 로고    scopus 로고
    • Claudin 4-targeted protein incorporated into PLGA nanoparticles can mediate M cell targeted delivery
    • Rajapaksa, T.E.; Stover-Hamer, M.; Fernandez, X.; Eckelhoefer, H.A.; Lo, D.D. Claudin 4-targeted protein incorporated into PLGA nanoparticles can mediate M cell targeted delivery. J. Control Release, 2010, 142(2), 196-205.
    • (2010) J. Control Release , vol.142 , Issue.2 , pp. 196-205
    • Rajapaksa, T.E.1    Stover-Hamer, M.2    Fernandez, X.3    Eckelhoefer, H.A.4    Lo, D.D.5
  • 84
    • 80054754759 scopus 로고    scopus 로고
    • Activation of antigen-specific T cell-responses by mannandecorated PLGA nanoparticles
    • Hamdy, S.; Haddadi, A.; Shayeganpour, A.; Samuel, J.; Lavasanifar, A. Activation of antigen-specific T cell-responses by mannandecorated PLGA nanoparticles. Pharm. Res., 2011, 28(9), 2288-2301.
    • (2011) Pharm. Res. , vol.28 , Issue.9 , pp. 2288-2301
    • Hamdy, S.1    Haddadi, A.2    Shayeganpour, A.3    Samuel, J.4    Lavasanifar, A.5
  • 85
    • 1842638560 scopus 로고    scopus 로고
    • Folate receptor targeted biodegradable polymeric doxorubicin micelles
    • DOI 10.1016/j.jconrel.2004.02.003, PII S0168365904000811
    • Yoo, H.S.; Park, T.G. Folate receptor targeted biodegradable polymeric doxorubicin micelles. J. Control Release, 2004, 96(2), 273-283. (Pubitemid 38481509)
    • (2004) Journal of Controlled Release , vol.96 , Issue.2 , pp. 273-283
    • Yoo, H.S.1    Park, T.G.2
  • 86
    • 24344471360 scopus 로고    scopus 로고
    • Preparation and in vitro anticancer activity of wheat germ agglutinin (WGA)-conjugated PLGA nanoparticles loaded with paclitaxel and isopropyl myristate
    • DOI 10.1016/j.jconrel.2004.06.024, PII S0168365905002828
    • Mo, Y.; Lim, L.Y. Preparation and in vitro anticancer activity of wheat germ agglutinin (WGA)-conjugated PLGA nanoparticles loaded with paclitaxel and isopropyl myristate. J. Control Release, 2005, 107(1), 30-42. (Pubitemid 41253700)
    • (2005) Journal of Controlled Release , vol.107 , Issue.1 , pp. 30-42
    • Mo, Y.1    Lim, L.-Y.2
  • 87
    • 33846410672 scopus 로고    scopus 로고
    • Folate-decorated poly(lactide-co-glycolide)-vitamin E TPGS nanoparticles for targeted drug delivery
    • DOI 10.1016/j.biomaterials.2006.12.018, PII S0142961206010313
    • Zhang, Z.; Huey Lee, S.; Feng, S.S. Folate-decorated poly(lactideco- glycolide)-vitamin E TPGS nanoparticles for targeted drug delivery. Biomaterials, 2007, 28(10), 1889-1899. (Pubitemid 46137995)
    • (2007) Biomaterials , vol.28 , Issue.10 , pp. 1889-1899
    • Zhang, Z.1    Huey Lee, S.2    Feng, S.-S.3
  • 88
    • 44649106961 scopus 로고    scopus 로고
    • Preparation and characterization of PE38KDEL-loaded anti-HER2 nanoparticles for targeted cancer therapy
    • Chen, H.; Gao, J.; Lu, Y.; Kou, G.; Zhang, H.; Fan, L.; Sun, Z.; Guo, Y.; Zhong, Y. Preparation and characterization of PE38KDEL-loaded anti-HER2 nanoparticles for targeted cancer therapy. J. Control Release, 2008, 128(3), 209-216.
    • (2008) J. Control Release , vol.128 , Issue.3 , pp. 209-216
    • Chen, H.1    Gao, J.2    Lu, Y.3    Kou, G.4    Zhang, H.5    Fan, L.6    Sun, Z.7    Guo, Y.8    Zhong, Y.9
  • 89
    • 56249097260 scopus 로고    scopus 로고
    • Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles
    • Dhar, S.; Gu, F.X.; Langer, R.; Farokhzad, O.C.; Lippard, S.J. Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles. Proc. Natl. Acad. Sci. U S A, 2008, 105(45), 17356-17361.
    • (2008) Proc. Natl. Acad. Sci. U S A , vol.105 , Issue.45 , pp. 17356-17361
    • Dhar, S.1    Gu, F.X.2    Langer, R.3    Farokhzad, O.C.4    Lippard, S.J.5
  • 91
    • 63949084752 scopus 로고    scopus 로고
    • Design of a multifunctional PLGA nanoparticulate drug delivery system: Evaluation of its physicochemical properties and anticancer activity to malignant cancer cells
    • Wang, Z.; Chui, W.K.; Ho, P.C. Design of a multifunctional PLGA nanoparticulate drug delivery system: Evaluation of its physicochemical properties and anticancer activity to malignant cancer cells. Pharm. Res., 2009, 26(5), 1162-1171.
    • (2009) Pharm. Res. , vol.26 , Issue.5 , pp. 1162-1171
    • Wang, Z.1    Chui, W.K.2    Ho, P.C.3
  • 93
    • 67349243616 scopus 로고    scopus 로고
    • Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance
    • Patil, Y.; Sadhukha, T.; Ma, L.; Panyam, J. Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance. J. Control Release, 2009, 136(1), 21-29.
    • (2009) J. Control Release , vol.136 , Issue.1 , pp. 21-29
    • Patil, Y.1    Sadhukha, T.2    Ma, L.3    Panyam, J.4
  • 94
    • 68749092564 scopus 로고    scopus 로고
    • Targeted epidermal growth factor receptor nanoparticle bioconjugates for breast cancer therapy
    • Acharya, S.; Dilnawaz, F.; Sahoo, S.K. Targeted epidermal growth factor receptor nanoparticle bioconjugates for breast cancer therapy. Biomaterials, 2009, 30(29), 5737-5750.
    • (2009) Biomaterials , vol.30 , Issue.29 , pp. 5737-5750
    • Acharya, S.1    Dilnawaz, F.2    Sahoo, S.K.3
  • 95
    • 70350707597 scopus 로고    scopus 로고
    • The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance
    • Patil, Y.B.; Swaminathan, S.K.; Sadhukha, T.; Ma, L.; Panyam, J. The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance. Biomaterials, 2010, 31(2), 358-365.
    • (2010) Biomaterials , vol.31 , Issue.2 , pp. 358-365
    • Patil, Y.B.1    Swaminathan, S.K.2    Sadhukha, T.3    Ma, L.4    Panyam, J.5
  • 96
    • 72149086003 scopus 로고    scopus 로고
    • LyP-1-conjugated nanoparticles for targeting drug delivery to lymphatic metastatic tumors
    • Luo, G.; Yu, X.; Jin, C.; Yang, F.; Fu, D.; Long, J.; Xu, J.; Zhan, C.; Lu, W. LyP-1-conjugated nanoparticles for targeting drug delivery to lymphatic metastatic tumors. Int. J. Pharm., 2010, 385(1-2), 150-156.
    • (2010) Int. J. Pharm. , vol.385 , Issue.1-2 , pp. 150-156
    • Luo, G.1    Yu, X.2    Jin, C.3    Yang, F.4    Fu, D.5    Long, J.6    Xu, J.7    Zhan, C.8    Lu, W.9
  • 97
    • 72949119124 scopus 로고    scopus 로고
    • Integrins in cancer: Biological implications and therapeutic opportunities
    • Desgrosellier, J.S.; Cheresh, D.A. Integrins in cancer: Biological implications and therapeutic opportunities. Nat. Rev. Cancer, 2010, 10(1), 9-22.
    • (2010) Nat. Rev. Cancer , vol.10 , Issue.1 , pp. 9-22
    • Desgrosellier, J.S.1    Cheresh, D.A.2
  • 98
    • 77955108815 scopus 로고    scopus 로고
    • Enhanced oral bioavailability of paclitaxel formulated in vitamin E-TPGS emulsified nanoparticles of biodegradable polymers: In vitro and in vivo studies
    • Zhao, L.; Feng, S.S.; Enhanced oral bioavailability of paclitaxel formulated in vitamin E-TPGS emulsified nanoparticles of biodegradable polymers: In vitro and in vivo studies. J. Pharm. Sci., 2010, 99(8), 3552-3560.
    • (2010) J. Pharm. Sci. , vol.99 , Issue.8 , pp. 3552-3560
    • Zhao, L.1    Feng, S.S.2
  • 100
    • 78449233395 scopus 로고    scopus 로고
    • The effect of the oral administration of polymeric nanoparticles on the efficacy and toxicity of tamoxifen
    • Jain, A.K.; Swarnakar, N.K.; Godugu, C.; Singh, R.P.; Jain, S.The effect of the oral administration of polymeric nanoparticles on the efficacy and toxicity of tamoxifen. Biomaterials, 2011, 32(2), 503-515.
    • (2011) Biomaterials , vol.32 , Issue.2 , pp. 503-515
    • Jain, A.K.1    Swarnakar, N.K.2    Godugu, C.3    Singh, R.P.4    Jain, S.5
  • 101
    • 80051817418 scopus 로고    scopus 로고
    • Aptamer-functionalized PEG-PLGA nanoparticles for enhanced anti-glioma drug delivery
    • Guo, J.; Gao, X.; Su, L.; Xia, H.; Gu, G.; Pang, Z.; Jiang, X.; Yao, L.; Chen, J.; Chen, H. Aptamer-functionalized PEG-PLGA nanoparticles for enhanced anti-glioma drug delivery. Biomaterials, 2011, 32(31), 8010-8020.
    • (2011) Biomaterials , vol.32 , Issue.31 , pp. 8010-8020
    • Guo, J.1    Gao, X.2    Su, L.3    Xia, H.4    Gu, G.5    Pang, Z.6    Jiang, X.7    Yao, L.8    Chen, J.9    Chen, H.10
  • 102
    • 79959514159 scopus 로고    scopus 로고
    • Improved therapeutic effect of folate-decorated PLGA-PEG nanoparticles for endometrial carcinoma
    • Liang, C.; Yang, Y.; Ling, Y.; Huang, Y.; Li, T.; Li, X. Improved therapeutic effect of folate-decorated PLGA-PEG nanoparticles for endometrial carcinoma. Bioorg. Med. Chem., 2011, 19(13), 4057-4066.
    • (2011) Bioorg. Med. Chem. , vol.19 , Issue.13 , pp. 4057-4066
    • Liang, C.1    Yang, Y.2    Ling, Y.3    Huang, Y.4    Li, T.5    Li, X.6
  • 104
    • 84859996647 scopus 로고    scopus 로고
    • Modern methods for delivery of drugs across the blood-brain barrier
    • Chen, Y.; Liu, L. Modern methods for delivery of drugs across the blood-brain barrier. Adv. Drug. Deliv. Rev., 2012, 64(7), 640-665.
    • (2012) Adv. Drug. Deliv. Rev. , vol.64 , Issue.7 , pp. 640-665
    • Chen, Y.1    Liu, L.2
  • 105
    • 84862659050 scopus 로고    scopus 로고
    • Therapeutics imaging and toxicity of nanomaterials in the central nervous system
    • Nunes, A.; Al-Jamal, K.T.; Kostarelos, K. Therapeutics, imaging and toxicity of nanomaterials in the central nervous system. J. Control Release, 2012, 161(2), 290-306.
    • (2012) J. Control Release , vol.161 , Issue.2 , pp. 290-306
    • Nunes, A.1    Al-Jamal, K.T.2    Kostarelos, K.3
  • 106
    • 70449529637 scopus 로고    scopus 로고
    • Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases
    • Gabathuler, R. Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases. Neurobiol. Dis., 2010, 37(1), 48-57.
    • (2010) Neurobiol. Dis. , vol.37 , Issue.1 , pp. 48-57
    • Gabathuler, R.1
  • 107
    • 0035748363 scopus 로고    scopus 로고
    • Peptide drug modifications to enhance bioavailability and bloodbrain barrier permeability
    • Witt, K.A.; Gillespie, T.J.; Huber, J.D.; Egleton, R.D.; Davis, T.P. Peptide drug modifications to enhance bioavailability and bloodbrain barrier permeability. Peptides, 2001, 22(12), 2329-2343.
    • (2001) Peptides , vol.22 , Issue.12 , pp. 2329-2343
    • Witt, K.A.1    Gillespie, T.J.2    Huber, J.D.3    Egleton, R.D.4    Davis, T.P.5
  • 108
    • 26944477353 scopus 로고    scopus 로고
    • Peptide-derivatized biodegradable nanoparticles able to cross the blood-brain barrier
    • DOI 10.1016/j.jconrel.2005.07.013, PII S0168365905003305
    • Costantino, L.; Gandolfi, F.; Tosi, G.; Rivasi, F.; Vandelli, M.A.; Forni, F. Peptide-derivatized biodegradable nanoparticles able to cross the blood-brain barrier. J. Control Release, 2005, 108(1), 84-96. (Pubitemid 41476677)
    • (2005) Journal of Controlled Release , vol.108 , Issue.1 , pp. 84-96
    • Costantino, L.1    Gandolfi, F.2    Tosi, G.3    Rivasi, F.4    Vandelli, M.A.5    Forni, F.6
  • 109
    • 12344319635 scopus 로고    scopus 로고
    • Development of neuropeptide drugs that cross the blood-brain barrier
    • DOI 10.1602/neurorx.2.1.44
    • Egleton, R.D.; Davis, T.P. Development of neuropeptide drugs that cross the blood-brain barrier. NeuroRx., 2005, 2(1), 44-53. (Pubitemid 40128025)
    • (2005) NeuroRx , vol.2 , Issue.1 , pp. 44-53
    • Egleton, R.D.1    Davis, T.P.2
  • 112
    • 33646862602 scopus 로고    scopus 로고
    • Nanoparticulate drug carriers based on hybrid poly(d,l-lactide-co- glycolide)-dendron structures
    • DOI 10.1016/j.biomaterials.2006.04.026, PII S0142961206003826
    • Costantino, L.; Gandolfi, F.; Bossy-Nobs, L.; Tosi, G.; Gurny, R.; Rivasi, F.; Vandelli, M.A.; Forni, F. Nanoparticulate drug carriers based on hybrid poly(D,L-lactide-co-glycolide)-dendron structures. Biomaterials, 2006, 27(26), 4635-4645. (Pubitemid 43783224)
    • (2006) Biomaterials , vol.27 , Issue.26 , pp. 4635-4645
    • Costantino, L.1    Gandolfi, F.2    Bossy-Nobs, L.3    Tosi, G.4    Gurny, R.5    Rivasi, F.6    Angela Vandelli, M.7    Forni, F.8
  • 113
    • 0004308925 scopus 로고
    • Process for the preparation of dispersible colloidal systems of a substance in the form of nanoparticles
    • Fessi, H.; Devissaguet, J. P.; Puisieux, F.; Thies, C. Process for the preparation of dispersible colloidal systems of a substance in the form of nanoparticles. US Patent No.5, 1992, 118 528.
    • (1992) US Patent No.5 , vol.118 , pp. 528
    • Fessi, H.1    Devissaguet, J.P.2    Puisieux, F.3    Thies, C.4
  • 114
    • 0032901219 scopus 로고    scopus 로고
    • Encapsulation of hydrophilic and lipophilic drugs in PLGA nanoparticles by the nanoprecipitation method
    • DOI 10.1081/DDC-100102197
    • Barichello, J.M.; Morishita, M.; Takayama, K.; Nagai, T. Encapsulation of hydrophilic and lipophilic drugs in PLGA nanoparticles by the nanoprecipitation method. Drug. Dev. Ind. Pharm., 1999, 25(4), 471-476. (Pubitemid 29159426)
    • (1999) Drug Development and Industrial Pharmacy , vol.25 , Issue.4 , pp. 471-476
    • Barichello, J.M.1    Morishita, M.2    Takayama, K.3    Nagai, T.4
  • 115
    • 0032472391 scopus 로고    scopus 로고
    • Influence of experimental parameters on the characteristics of poly(lactic acid) nanoparticles prepared by a double emulsion method
    • DOI 10.1016/S0168-3659(97)00106-5, PII S0168365997001065
    • Zambaux, M.F.; Bonneaux, F.; Gref, R.; Maincent, P.; Dellacherie, E.; Alonso, M.J.; Labrude, P.; Vigneron, C. Influence of experimental parameters on the characteristics of poly(lactic acid) nanoparticles prepared by a double emulsion method. J. Control Release, 1998, 50(1-3), 31-40. (Pubitemid 28044098)
    • (1998) Journal of Controlled Release , vol.50 , Issue.1-3 , pp. 31-40
    • Zambaux, M.F.1    Bonneaux, F.2    Gref, R.3    Maincent, P.4    Dellacherie, E.5    Alonso, M.J.6    Labrude, P.7    Vigneron, C.8
  • 116
    • 80052970386 scopus 로고    scopus 로고
    • Strategies for the nanoencapsulation of hydrophilic molecules in polymer-based nanoparticles
    • Vrignaud, S.; Benoit, J. P.; Saulnier, P. Strategies for the nanoencapsulation of hydrophilic molecules in polymer-based nanoparticles. Biomaterials, 2011, 32(33), 8593-8604.
    • (2011) Biomaterials , vol.32 , Issue.33 , pp. 8593-8604
    • Vrignaud, S.1    Benoit, J.P.2    Saulnier, P.3
  • 117
    • 0037335187 scopus 로고    scopus 로고
    • Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles
    • DOI 10.1023/A:1022604120952
    • Kreuter, J.; Ramge, P.; Petrov, V.; Hamm, S.; Gelperina, S.E.; Engelhardt, B.; Alyautdin, R.; von Briesen, H.; Begley, D.J. Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles. Pharm. Res., 2003, 20(3), 409-416. (Pubitemid 36288370)
    • (2003) Pharmaceutical Research , vol.20 , Issue.3 , pp. 409-416
    • Kreuter, J.1    Ramge, P.2    Petrov, V.3    Hamm, S.4    Gelperina, S.E.5    Engelhardt, B.6    Alyautdin, R.7    Von Briesen, H.8    Begley, D.J.9
  • 118
    • 24144479258 scopus 로고    scopus 로고
    • Glycosylated neuropeptides: A new vista for neuropsychopharmacology?
    • DOI 10.1002/med.20039
    • Polt, R.; Dhanasekaran, M.; Keyari, C.M. Glycosylated neuropeptides: A new vista for neuropsychopharmacology? Med. Res. Rev., 2005, 25(5), 557-585. (Pubitemid 41233371)
    • (2005) Medicinal Research Reviews , vol.25 , Issue.5 , pp. 557-585
    • Polt, R.1    Dhanasekaran, M.2    Keyari, C.M.3
  • 119
    • 34548041658 scopus 로고    scopus 로고
    • Targeting the central nervous system: In vivo experiments with peptide-derivatized nanoparticles loaded with Loperamide and Rhodamine-123
    • DOI 10.1016/j.jconrel.2007.05.022, PII S0168365907002660
    • Tosi, G.; Costantino, L.; Rivasi, F.; Ruozi, B.; Leo, E.; Vergoni, A.V.; Tacchi, R.; Bertolini, A.; Vandelli, M.A.; Forni, F. Targeting the central nervous system: In vivo experiments with peptidederivatized nanoparticles loaded with Loperamide and Rhodamine-123. J. Control Release, 2007, 122(1), 1-9. (Pubitemid 47284547)
    • (2007) Journal of Controlled Release , vol.122 , Issue.1 , pp. 1-9
    • Tosi, G.1    Costantino, L.2    Rivasi, F.3    Ruozi, B.4    Leo, E.5    Vergoni, A.V.6    Tacchi, R.7    Bertolini, A.8    Vandelli, M.A.9    Forni, F.10
  • 120
  • 122
    • 84877957265 scopus 로고    scopus 로고
    • Brain-targeted polymeric nanoparticles: In vivo evidences after different routes of administration in rodents
    • accepted
    • Tosi, G.; Ruozi, B.; Belletti, D.; Vilella, A.; Zoli, M.; Vandelli, M.A.; Forni, F. Brain-targeted polymeric nanoparticles: In vivo evidences after different routes of administration in rodents. Nanomedicine, 2012, accepted.
    • (2012) Nanomedicine
    • Tosi, G.1    Ruozi, B.2    Belletti, D.3    Vilella, A.4    Zoli, M.5    Vandelli, M.A.6    Forni, F.7
  • 123
    • 12344335788 scopus 로고    scopus 로고
    • Conjugated poly(D,L-lactide-co-glycolide) for the preparation of in vivo detectable nanoparticles
    • DOI 10.1016/j.biomaterials.2004.10.025, PII S0142961204009457
    • Tosi, G.; Rivasi, F.; Gandolfi, F.; Costantino, L.; Vandelli, M.A.; Forni, F. Conjugated poly(D,L-lactide-co-glycolide) for the preparation of in vivo detectable nanoparticles. Biomaterials, 2005, 26(19), 4189-4195. (Pubitemid 40138665)
    • (2005) Biomaterials , vol.26 , Issue.19 , pp. 4189-4195
    • Tosi, G.1    Rivasi, F.2    Gandolfi, F.3    Costantino, L.4    Vandelli, M.A.5    Forni, F.6
  • 124
    • 79952933732 scopus 로고    scopus 로고
    • Development of novel Zn2+ loaded nanoparticles designed for cell-type targeted drug release in CNS neurons: In vitro evidences
    • Grabrucker, A.M.; Garner, C.C.; Boeckers, T.M.; Bondioli, L.; Ruozi, B.; Forni, F.; Vandelli, M.A.; Tosi, G. Development of novel Zn2+ loaded nanoparticles designed for cell-type targeted drug release in CNS neurons: In vitro evidences. PLoS One, 2011, 6(3), e17851.
    • (2011) PLoS One , vol.6 , Issue.3
    • Grabrucker, A.M.1    Garner, C.C.2    Boeckers, T.M.3    Bondioli, L.4    Ruozi, B.5    Forni, F.6    Vandelli, M.A.7    Tosi, G.8
  • 125
    • 14144255733 scopus 로고    scopus 로고
    • Lysosomal storage disorders
    • DOI 10.1111/j.1365-2141.2004.05293.x
    • Vellodi, A. Lysosomal storage disorders. Br. J. Haematol., 2005, 128(4), 413-431. (Pubitemid 40283160)
    • (2005) British Journal of Haematology , vol.128 , Issue.4 , pp. 413-431
    • Vellodi, A.1
  • 126
    • 0016201884 scopus 로고
    • Replacement therapy for inherited enzyme deficiency. Use of purified glucocerebrosidase in Gaucher's disease
    • Brady, R.O.; Pentchev, P.G.; Gal, A.E.; Hibbert, S.R.; Dekaban, A.S. Replacement therapy for inherited enzyme deficiency. Use of purified glucocerebrosidase in Gaucher's disease. N. Engl. J. Med., 1974, 291(19), 989-993.
    • (1974) N. Engl. J. Med. , vol.291 , Issue.19 , pp. 989-993
    • Brady, R.O.1    Pentchev, P.G.2    Gal, A.E.3    Hibbert, S.R.4    Dekaban, A.S.5
  • 127
    • 0032554169 scopus 로고    scopus 로고
    • First long-term results of imiglucerase therapy of type 1 Gaucher disease
    • Niederau, C.; vom Dahl, S.; Haussinger, D. First long-term results of imiglucerase therapy of type 1 Gaucher disease. Eur. J. Med. Res., 1998, 3(1-2), 25-30.
    • (1998) Eur. J. Med. Res. , vol.3 , Issue.1-2 , pp. 25-30
    • Niederau, C.1    Vom Dahl, S.2    Haussinger, D.3
  • 128
    • 34447295360 scopus 로고    scopus 로고
    • Neurologic improvement in a type 3 Gaucher disease patient treated with imiglucerase/miglustat combination
    • DOI 10.1111/j.1528-1167.2007.01074.x
    • Capablo, J.L.; Franco, R.; de Cabezon, A.S.; Alfonso, P.; Pocovi, M.; Giraldo, P. Neurologic improvement in a type 3 Gaucher disease patient treated with imiglucerase/miglustat combination. Epilepsia, 2007, 48(7), 1406-1408. (Pubitemid 47063084)
    • (2007) Epilepsia , vol.48 , Issue.7 , pp. 1406-1408
    • Capablo, J.L.1    Franco, R.2    De Cabezon, A.S.3    Alfonso, P.4    Pocovi, M.5    Giraldo, P.6
  • 129
    • 77950361615 scopus 로고    scopus 로고
    • Phenotype variations in early onset Pompe disease: Diagnosis and treatment results with Myozyme
    • Pascual, S.I. Phenotype variations in early onset Pompe disease: Diagnosis and treatment results with Myozyme. Adv. Exp. Med. Biol., 2009, 652, 39-46.
    • (2009) Adv. Exp. Med. Biol. , vol.652 , pp. 39-46
    • Pascual, S.I.1
  • 130
    • 84855575334 scopus 로고    scopus 로고
    • Therapy for the mucopolysaccharidoses
    • Valayannopoulos, V.; Wijburg, F.A. Therapy for the mucopolysaccharidoses. Rheumatology, 2011, 50(S5), v49-59.
    • (2011) Rheumatology , vol.50 , Issue.S5
    • Valayannopoulos, V.1    Wijburg, F.A.2
  • 131
    • 84871031500 scopus 로고    scopus 로고
    • Effects of enzyme replacement therapy in adult patients with Fabry disease on cardiac structure and function: A retrospective cohort study of the Fabry Munster Study (FaMuS) data
    • Engelen, M.A.; Brand, E.; Baumeister, T.B.; Marquardt, T.; Duning, T.; Osada, N.; Schaefer, R.M.; Stypmann, J. Effects of enzyme replacement therapy in adult patients with Fabry disease on cardiac structure and function: A retrospective cohort study of the Fabry Munster Study (FaMuS) data. B.M.J. Open, 2012, 2:e000879.
    • (2012) B.M.J. Open , vol.2
    • Engelen, M.A.1    Brand, E.2    Baumeister, T.B.3    Marquardt, T.4    Duning, T.5    Osada, N.6    Schaefer, R.M.7    Stypmann, J.8
  • 132
    • 84873184451 scopus 로고    scopus 로고
    • New strategies for the treatment of lysosomal storage diseases (Review
    • Parenti, G.; Pignata, C.; Vajro, P.; Salerno, M. New strategies for the treatment of lysosomal storage diseases (Review). Int. J. Mol. Med., 2013, 31(1), 11-20.
    • (2013) Int. J. Mol. Med. , vol.31 , Issue.1 , pp. 11-20
    • Parenti, G.1    Pignata, C.2    Vajro, P.3    Salerno, M.4
  • 136
    • 41549103661 scopus 로고    scopus 로고
    • Methoxy poly(ethylene glycol) - Low molecular weight linear polyethylenimine-derived copolymers enable polyplex shielding
    • DOI 10.1016/j.ejpb.2007.10.006, PII S0939641107003463
    • Lungwitz, U.; Breunig, M.; Liebl, R.; Blunk, T.; Goepferich, A. Methoxy poly(ethylene glycol)-low molecular weight linear polyethylenimine-derived copolymers enable polyplex shielding. Eur. J. Pharm. Biopharm., 2008, 69(1), 134-148. (Pubitemid 351467165)
    • (2008) European Journal of Pharmaceutics and Biopharmaceutics , vol.69 , Issue.1 , pp. 134-148
    • Lungwitz, U.1    Breunig, M.2    Liebl, R.3    Blunk, T.4    Goepferich, A.5
  • 138
    • 73449144099 scopus 로고    scopus 로고
    • Progress towards liver and lung-directed gene therapy with helper-dependent adenoviral vectors
    • Brunetti-Pierri, N.; Ng, P. Progress towards liver and lung-directed gene therapy with helper-dependent adenoviral vectors. Curr. Gene Ther., 2009, 9(5), 329-340.
    • (2009) Curr. Gene Ther. , vol.9 , Issue.5 , pp. 329-340
    • Brunetti-Pierri, N.1    Ng, P.2
  • 139
    • 72249104303 scopus 로고    scopus 로고
    • Adeno-associated viral vector (AAV)-mediated gene transfer in the red nucleus of the adult rat brain: Comparative analysis of the transduction properties of seven AAV serotypes and lentiviral vectors
    • Blits, B.; Derks, S.; Twisk, J.; Ehlert, E.; Prins, J.; Verhaagen, J. Adeno-associated viral vector (AAV)-mediated gene transfer in the red nucleus of the adult rat brain: Comparative analysis of the transduction properties of seven AAV serotypes and lentiviral vectors. J. Neurosci. Methods, 2010, 185(2), 257-263.
    • (2010) J. Neurosci. Methods , vol.185 , Issue.2 , pp. 257-263
    • Blits, B.1    Derks, S.2    Twisk, J.3    Ehlert, E.4    Prins, J.5    Verhaagen, J.6
  • 140
    • 42049114012 scopus 로고    scopus 로고
    • Nonviral approaches for neuronal delivery of nucleic acids
    • Bergen, J.M.; Park, I.K.; Horner, P.J.; Pun, S.H. Nonviral approaches for neuronal delivery of nucleic acids. Pharm. Res., 2008, 25(5), 983-998.
    • (2008) Pharm. Res. , vol.25 , Issue.5 , pp. 983-998
    • Bergen, J.M.1    Park, I.K.2    Horner, P.J.3    Pun, S.H.4
  • 141
    • 44049090692 scopus 로고    scopus 로고
    • AAV-mediated gene transfer for the treatment of hemophilia B: Problems and prospects
    • DOI 10.1038/gt.2008.71, PII GT200871, Special Issue: AAV Vectors for Clinical GeneTherapy
    • Hasbrouck, N.C.; High, K.A. AAV-mediated gene transfer for the treatment of hemophilia B: Problems and prospects. Gene Ther., 2008, 15(11), 870-875. (Pubitemid 351712621)
    • (2008) Gene Therapy , vol.15 , Issue.11 , pp. 870-875
    • Hasbrouck, N.C.1    High, K.A.2
  • 142
    • 73249137698 scopus 로고    scopus 로고
    • Low molecular weight polyethylenimine cross-linked by 2-hydroxypropyl-gammacyclodextrin coupled to peptide targeting HER2 as a gene delivery vector
    • Huang, H.; Yu, H.; Tang, G.; Wang, Q.; Li, J. Low molecular weight polyethylenimine cross-linked by 2-hydroxypropyl-gammacyclodextrin coupled to peptide targeting HER2 as a gene delivery vector. Biomaterials, 2010, 31(7), 1830-1838.
    • (2010) Biomaterials , vol.31 , Issue.7 , pp. 1830-1838
    • Huang, H.1    Yu, H.2    Tang, G.3    Wang, Q.4    Li, J.5
  • 143
    • 75149145129 scopus 로고    scopus 로고
    • The ability of a collagen/calcium phosphate scaffold to act as its own vector for gene delivery and to promote bone formation via transfection with VEGF(165
    • Keeney, M.; van den Beucken, J.J.; van der Kraan, P.M.; Jansen, J.A.; Pandit, A. The ability of a collagen/calcium phosphate scaffold to act as its own vector for gene delivery and to promote bone formation via transfection with VEGF(165). Biomaterials, 2010, 31 (10), 2893-2902.
    • (2010) Biomaterials , vol.31 , Issue.10 , pp. 2893-2902
    • Keeney, M.1    Van Den Beucken, J.J.2    Van Der Kraan, P.M.3    Jansen, J.A.4    Pandit, A.5
  • 144
    • 77951053004 scopus 로고    scopus 로고
    • Tumor site-specific silencing of NF-kappaB p65 by targeted hollow gold nanosphere-mediated photothermal transfection
    • Lu, W.; Zhang, G.; Zhang, R.; Flores, L.G.2nd; Huang, Q.; Gelovani, J. G.; Li, C. Tumor site-specific silencing of NF-kappaB p65 by targeted hollow
    • (2010) Cancer Res. , vol.70 , Issue.8 , pp. 3177-3188
    • Lu, W.1    Zhang, G.2    Zhang, R.3    Flores II, L.G.4    Huang, Q.5    Gelovani, J.G.6    Li, C.7
  • 145
    • 77950803130 scopus 로고    scopus 로고
    • Galactosylated poly(2-(2-aminoethyoxy)ethoxy)phosphazene/DNA complex nanoparticles: In vitro and in vivo evaluation for gene delivery
    • Yang, Y.; Zhang, Z.; Chen, L.; Gu, W.; Li, Y. Galactosylated poly(2-(2-aminoethyoxy)ethoxy)phosphazene/DNA complex nanoparticles: In vitro and in vivo evaluation for gene delivery. Biomacromolecules, 2010, 11(4), 927-933.
    • (2010) Biomacromolecules , vol.11 , Issue.4 , pp. 927-933
    • Yang, Y.1    Zhang, Z.2    Chen, L.3    Gu, W.4    Li, Y.5
  • 146
    • 0042063604 scopus 로고    scopus 로고
    • Immunogene therapy of recurrent glioblastoma multiforme with a liposomally encapsulated replication-incompetent Semliki forest virus vector carrying the human interleukin-12 gene - A phase I/II clinical protocol
    • DOI 10.1023/A:1024979103780
    • Ren, H.; Boulikas, T.; Lundstrom, K.; Soling, A.; Warnke, P.C.; Rainov, N.G.; Immunogene therapy of recurrent glioblastoma multiforme with a liposomally encapsulated replication-incompetent Semliki forest virus vector carrying the human interleukin-12 gene-A phase I/II clinical protocol. J. Neurooncol., 2003, 64(1-2), 147-154. (Pubitemid 36992469)
    • (2003) Journal of Neuro-Oncology , vol.64 , Issue.1-2 , pp. 147-154
    • Ren, H.1    Boulikas, T.2    Soling, A.3    Warnke, P.C.4    Rainov, N.G.5
  • 147
    • 2442767029 scopus 로고    scopus 로고
    • A phase I/II study of herpes simplex virus type 1 thymidine kinase 'Suicide' gene therapy for recurrent glioblastoma
    • DOI 10.1089/10430349850019436
    • Klatzmann, D.; Valery, C.A.; Bensimon, G.; Marro, B.; Boyer, O.; Mokhtari, K.; Diquet, B.; Salzmann, J.L.; Philippon, J. A phase I/II study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for recurrent glioblastoma. Study Group on Gene Therapy for Glioblastoma. Hum. Gene Ther., 1998, 9(17), 2595-2604. (Pubitemid 29004632)
    • (1998) Human Gene Therapy , vol.9 , Issue.17 , pp. 2595-2604
    • Klatzmann, D.1    Valery, C.A.2    Bensimon, G.3    Marro, B.4    Boyer, O.5    Mokhtari, K.6    Diquet, B.7    Salzmann, J.-L.8    Philippon, J.9
  • 148
    • 0034694011 scopus 로고    scopus 로고
    • A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme
    • Rainov, N.G. A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme. Hum. Gene Ther., 2000, 11(17), 2389-2401.
    • (2000) Hum. Gene Ther. , vol.11 , Issue.17 , pp. 2389-2401
    • Rainov, N.G.1
  • 149
    • 0037331856 scopus 로고    scopus 로고
    • Dynamics of endocytosis and exocytosis of poly(D,L-lactide-co-glycolide) nanoparticles in vascular smooth muscle cells
    • DOI 10.1023/A:1022219003551
    • Panyam, J.; Labhasetwar, V. Dynamics of endocytosis and exocytosis of poly(D,L-lactide-co-glycolide) nanoparticles in vascular smooth muscle cells. Pharm. Res., 2003, 20(2), 212-220. (Pubitemid 36277684)
    • (2003) Pharmaceutical Research , vol.20 , Issue.2 , pp. 212-220
    • Panyam, J.1    Labhasetwar, V.2
  • 150
    • 0037026269 scopus 로고    scopus 로고
    • Size-dependency of nanoparticle-mediated gene transfection: Studies with fractionated nanoparticles
    • DOI 10.1016/S0378-5173(02)00315-0, PII S0378517302003150
    • Prabha, S.; Zhou, W.Z.; Panyam, J.; Labhasetwar, V. Sizedependency of nanoparticle-mediated gene transfection: Studies with fractionated nanoparticles. Int. J. Pharm., 2002, 244(1-2), 105-115. (Pubitemid 35245451)
    • (2002) International Journal of Pharmaceutics , vol.244 , Issue.1-2 , pp. 105-115
    • Prabha, S.1    Zhou, W.-Z.2    Panyam, J.3    Labhasetwar, V.4
  • 152
    • 0032860574 scopus 로고    scopus 로고
    • Nuclear targeting peptide scaffolds for lipofection of nondividing mammalian cells
    • DOI 10.1038/12860
    • Subramanian, A.; Ranganathan, P.; Diamond, S. L. Nuclear targeting peptide scaffolds for lipofection of nondividing mammalian cells. Nat. Biotechnol., 1999, 17(9), 873-877. (Pubitemid 29416660)
    • (1999) Nature Biotechnology , vol.17 , Issue.9 , pp. 873-877
    • Subramanian, A.1    Ranganathan, P.2    Diamond, S.L.3
  • 154
    • 0033279841 scopus 로고    scopus 로고
    • Transport between the cell nucleus and the cytoplasm
    • DOI 10.1146/annurev.cellbio.15.1.607
    • Gorlich, D.; Kutay, U. Transport between the cell nucleus and the cytoplasm. Annu. Rev. Cell. Dev. Biol., 1999, 15 607-660. (Pubitemid 32250388)
    • (1999) Annual Review of Cell and Developmental Biology , vol.15 , pp. 607-660
    • Gorlich, D.1    Kutay, U.2
  • 155
    • 0024654338 scopus 로고
    • A nucleoprotein complex mediates the integration of retroviral DNA
    • Bowerman, B.; Brown, P.O.; Bishop, J.M.; Varmus, H.E. A nucleoprotein complex mediates the integration of retroviral DNA. Genes Dev., 1989, 3(4), 469-478.
    • (1989) Genes Dev. , vol.3 , Issue.4 , pp. 469-478
    • Bowerman, B.1    Brown, P.O.2    Bishop, J.M.3    Varmus, H.E.4
  • 156
    • 0027158091 scopus 로고
    • Integration of murine leukemia virus DNA depends on mitosis
    • Roe, T.; Reynolds, T.C.; Yu, G.; Brown, P.O.; Integration of murine leukemia virus DNA depends on mitosis. EMBO J., 1993, 12(5), 2099-2108. (Pubitemid 23157725)
    • (1993) EMBO Journal , vol.12 , Issue.5 , pp. 2099-2108
    • Roe, T.1    Reynolds, T.C.2    Yu, G.3    Brown, P.O.4
  • 158
    • 0037162715 scopus 로고    scopus 로고
    • HIV-1 integration in the human genome favors active genes and local hotspots
    • DOI 10.1016/S0092-8674(02)00864-4
    • Schroder, A.R.; Shinn, P.; Chen, H.; Berry, C.; Ecker, J.R.; Bushman, F. HIV-1 integration in the human genome favors active genes and local hotspots. Cell, 2002, 110(4), 521-529. (Pubitemid 35232295)
    • (2002) Cell , vol.110 , Issue.4 , pp. 521-529
    • Schroder, A.R.W.1    Shinn, P.2    Chen, H.3    Berry, C.4    Ecker, J.R.5    Bushman, F.6
  • 159
    • 0037841763 scopus 로고    scopus 로고
    • Transcription start regions in the human genome are favored targets for MLV integration
    • DOI 10.1126/science.1083413
    • Wu, X.; Li, Y.; Crise, B.; Burgess, S.M. Transcription start regions in the human genome are favored targets for MLV integration. Science, 2003, 300(5626), 1749-1751. (Pubitemid 36712571)
    • (2003) Science , vol.300 , Issue.5626 , pp. 1749-1751
    • Wu, X.1    Li, Y.2    Crise, B.3    Burgess, S.M.4
  • 160
    • 0142227237 scopus 로고    scopus 로고
    • Targeting survival: Integration site selection by retroviruses and LTR-Retrotransposons
    • DOI 10.1016/S0092-8674(03)00760-8
    • Bushman, F.D. Targeting survival: Integration site selection by retroviruses and LTR-retrotransposons. Cell, 2003, 115(2), 135-138. (Pubitemid 37329577)
    • (2003) Cell , vol.115 , Issue.2 , pp. 135-138
    • Bushman, F.D.1
  • 162
    • 0036842502 scopus 로고    scopus 로고
    • Site-specific genomic integration produces therapeutic factor IX levels in mice
    • DOI 10.1038/nbt753
    • Olivares, E.C.; Hollis, R.P.; Chalberg, T.W.; Meuse, L.; Kay, M.A.; Calos, M. P. Site-specific genomic integration produces therapeutic Factor IX levels in mice. Nat. Biotechnol, 2002, 20 (11), 1124-1128. (Pubitemid 35285441)
    • (2002) Nature Biotechnology , vol.20 , Issue.11 , pp. 1124-1128
    • Olivares, E.C.1    Hollis, R.P.2    Chalberg, T.W.3    Meuse, L.4    Kay, M.A.5    Calos, M.P.6
  • 163
    • 0030662074 scopus 로고    scopus 로고
    • Molecular reconstruction of sleeping beauty, a Tc1-like transposon from fish, and its transposition in human cells
    • Ivics, Z.; Hackett, P.B.; Plasterk, R.H.; Izsvak, Z. Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells. Cell, 1997, 91(4), 501-510. (Pubitemid 27508239)
    • (1997) Cell , vol.91 , Issue.4 , pp. 501-510
    • Ivics, Z.1    Hackett, P.B.2    Plasterk, R.H.3    Izsvak, Z.4
  • 165
    • 70349779189 scopus 로고    scopus 로고
    • Efficient stable gene transfer into human cells by the Sleeping Beauty transposon vectors
    • Izsvak, Z.; Chuah, M. K.; Vandendriessche, T.; Ivics, Z. Efficient stable gene transfer into human cells by the Sleeping Beauty transposon vectors. Methods, 2009, 49 (3), 287-297.
    • (2009) Methods , vol.49 , Issue.3 , pp. 287-297
    • Izsvak, Z.1    Chuah, M.K.2    Vandendriessche, T.3    Ivics, Z.4
  • 166
    • 68849130485 scopus 로고    scopus 로고
    • Nanocapsuledelivered Sleeping Beauty mediates therapeutic Factor VIII expression in liver sinusoidal endothelial cells of hemophilia A mice
    • Kren, B.T.; Unger, G.M.; Sjeklocha, L.; Trossen, A.A.; Korman, V.; Diethelm-Okita, B.M.; Reding, M.T.; Steer, C.J. Nanocapsuledelivered Sleeping Beauty mediates therapeutic Factor VIII expression in liver sinusoidal endothelial cells of hemophilia A mice. J. Clin. Invest., 2009, 119(7), 2086-2099.
    • (2009) J. Clin. Invest. , vol.119 , Issue.7 , pp. 2086-2099
    • Kren, B.T.1    Unger, G.M.2    Sjeklocha, L.3    Trossen, A.A.4    Korman, V.5    Diethelm-Okita, B.M.6    Reding, M.T.7    Steer, C.J.8
  • 167
    • 0019128294 scopus 로고
    • Endocytosis of asialoglycoprotein-enzyme conjugates by hepatocytes
    • Stockert, R.J.; Haimes, H.B.; Morell, A.G.; Novikoff, P.M.; Novikoff, A.B.; Quintana, N.; Sternlieb, I. Endocytosis of asialoglycoprotein-enzyme conjugates by hepatocytes. Lab. Invest., 1980, 43(6), 556-563. (Pubitemid 11209843)
    • (1980) Laboratory Investigation , vol.43 , Issue.6 , pp. 556-563
    • Stockert, R.J.1    Haimes, H.B.2    Morell, A.G.3
  • 168
    • 1342290203 scopus 로고    scopus 로고
    • Development of hyperactive Sleeping Beauty transposon vectors by mutational analysis
    • DOI 10.1016/j.ymthe.2003.11.024
    • Zayed, H.; Izsvak, Z.; Walisko, O.; Ivics, Z. Development of hyperactive sleeping beauty transposon vectors by mutational analysis. Mol. Ther., 2004, 9(2), 292-304. (Pubitemid 38256555)
    • (2004) Molecular Therapy , vol.9 , Issue.2 , pp. 292-304
    • Zayed, H.1    Izsvak, Z.2    Walisco, O.3    Ivics, Z.4
  • 169
    • 33645861655 scopus 로고    scopus 로고
    • Gene therapy for lysosomal storage diseases
    • Sands, M.S.; Davidson, B.L. Gene therapy for lysosomal storage diseases. Mol. Ther., 2006, 13(5), 839-849.
    • (2006) Mol. Ther. , vol.13 , Issue.5 , pp. 839-849
    • Sands, M.S.1    Davidson, B.L.2
  • 171
    • 0032758906 scopus 로고    scopus 로고
    • Sustained production of beta-glucuronidase from localized sites after AAV vector gene transfer results in widespread distribution of enzyme and reversal of lysosomal storage lesions in a large volume of brain in mucopolysaccharidosis VII mice
    • Skorupa, A.F.; Fisher, K.J.; Wilson, J.M.; Parente, M.K.; Wolfe, J.H. Sustained production of beta-glucuronidase from localized sites after AAV vector gene transfer results in widespread distribution of enzyme and reversal of lysosomal storage lesions in a large volume of brain in mucopolysaccharidosis VII mice. Exp. Neurol., 1999, 160(1), 17-27.
    • (1999) Exp. Neurol. , vol.160 , Issue.1 , pp. 17-27
    • Skorupa, A.F.1    Fisher, K.J.2    Wilson, J.M.3    Parente, M.K.4    Wolfe, J.H.5
  • 172
    • 0033642895 scopus 로고    scopus 로고
    • Long-term and significant correction of brain lesions in adult mucopolysaccharidosis type VII mice using recombinant AAV vectors
    • Bosch, A.; Perret, E.; Desmaris, N.; Heard, J.M. Long-term and significant correction of brain lesions in adult mucopolysaccharidosis type VII mice using recombinant AAV vectors. Mol. Ther., 2000, 1(1), 63-70.
    • (2000) Mol. Ther. , vol.1 , Issue.1 , pp. 63-70
    • Bosch, A.1    Perret, E.2    Desmaris, N.3    Heard, J.M.4
  • 173
    • 0034986419 scopus 로고    scopus 로고
    • Intracranial injection of recombinant adeno-associated virus improves cognitive function in a murine model of mucopolysaccharidosis type VII
    • DOI 10.1006/mthe.2001.0274
    • Frisella, W.A.; O'Connor, L.H.; Vogler, C.A.; Roberts, M.; Walkley, S.; Levy, B.; Daly, T. M.; Sands, M.S. Intracranial injection of recombinant adeno-associated virus improves cognitive function in a murine model of mucopolysaccharidosis type VII. Mol. Ther., 2001, 3(3), 351-358. (Pubitemid 32514651)
    • (2001) Molecular Therapy , vol.3 , Issue.3 , pp. 351-358
    • Frisella, W.A.1    O'Connor, L.H.2    Vogler, C.A.3    Roberts, M.4    Walkley, S.5    Levy, B.6    Daly, T.M.7    Sands, M.S.8
  • 175
    • 84872335510 scopus 로고    scopus 로고
    • Multicomponent nanoparticles as nonviral vectors for the treatment of Fabry disease by gene therapy. Drug. Des
    • Ruiz de Garibay, A.P.; Delgado, D.; Del Pozo-Rodriguez, A.; Solinis, M.A.; Gascon, A.R. Multicomponent nanoparticles as nonviral vectors for the treatment of Fabry disease by gene therapy. Drug. Des. Devel. Ther., 2012, 6, 303-310.
    • (2012) Devel. Ther. , vol.6 , pp. 303-310
    • Ruiz De Garibay, A.P.1    Delgado, D.2    Del Pozo-Rodriguez, A.3    Solinis, M.A.4    Gascon, A.R.5
  • 176
    • 0035980982 scopus 로고    scopus 로고
    • Design and gene delivery activity of modified polyethylenimines
    • DOI 10.1016/S0169-409X(01)00202-2, PII S0169409X01002022
    • Kircheis, R.; Wightman, L.; Wagner, E. Design and gene delivery activity of modified polyethylenimines. Adv. Drug. Deliv. Rev., 2001, 53(3), 341-358. (Pubitemid 34024914)
    • (2001) Advanced Drug Delivery Reviews , vol.53 , Issue.3 , pp. 341-358
    • Kircheis, R.1    Wightman, L.2    Wagner, E.3


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