The ability of a collagen/calcium phosphate scaffold to act as its own vector for gene delivery and to promote bone formation via transfection with VEGF165

Biomaterials

Volumn 31, Issue 10, 2010, Pages 2893-2902

  Keeney, Michael ^a   van den Beucken, Jeroen J J P ^b   van der Kraan, Peter M ^b   Jansen, John A ^b   Pandit, Abhay ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Bone tissue engineering; Calcium phosphate; Collagen; Gene therapy

Indexed keywords

ANGIOGENESIS; BONE FORMATION; BONE RECONSTRUCTION; BONE TISSUE ENGINEERING; BONE VOLUME; COLLAGEN GENE; DEFECT SITES; EXTRACELLULAR MATRICES; GALACTOSIDASES; GENE DELIVERY; IN-VIVO; MOUSE MODELS; MRNA LEVEL; MURINE MODEL; NAKED PLASMID DNA; NONVIRAL VECTORS; PAMAM DENDRIMER; PLASMID DNA; PLASMID ENCODING; VASCULAR ENDOTHELIAL GROWTH FACTOR;

BONE; CALCIUM; CALCIUM ALLOYS; COLLAGEN; DENDRIMERS; DNA; GENE THERAPY; GENE TRANSFER; MICROBIOLOGY; NUCLEIC ACIDS; PHOSPHATES; SCAFFOLDS; TISSUE ENGINEERING;

CALCIUM PHOSPHATE;

BETA GALACTOSIDASE; CALCIUM PHOSPHATE; COLLAGEN; DENDRIMER; MESSENGER RNA; NAKED DNA; PLASMID DNA; POLYAMIDOAMINE; VASCULOTROPIN 165;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEFECT; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; FEMUR; GENETIC TRANSFECTION; MALE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OSSIFICATION; PRIORITY JOURNAL;

ANIMALS; BLOOD VESSELS; CALCIUM PHOSPHATES; COLLAGEN; FEMUR; GENE EXPRESSION; GENES, REPORTER; IMPLANTS, EXPERIMENTAL; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PATHOLOGIC; OSTEOGENESIS; SUBCUTANEOUS TISSUE; TISSUE SCAFFOLDS; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

MURINAE;

EID: 75149145129     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.12.041     Document Type: Article

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