메뉴 건너뛰기




Volumn 19, Issue 1, 2011, Pages 67-78

Lectin anchored PLGA nanoparticles for oral mucosal immunization against hepatitis B

Author keywords

Hepatitis B; lectin; M cells; mucosal immunization; nanoparticles

Indexed keywords

GAMMA INTERFERON; HEPATITIS B SURFACE ANTIGEN; INTERLEUKIN 2; LECTIN; NANOCARRIER; NANOPARTICLE; POLYGLACTIN; SECRETORY IMMUNOGLOBULIN;

EID: 78650042168     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/10611861003733946     Document Type: Article
Times cited : (76)

References (59)
  • 1
    • 0027259027 scopus 로고
    • Stability of liposomes in vitro and their uptake by rat Peyer's patches following oral administration
    • Aramaki Y, Tomizawa H, Hara T, Yachi K, Kikuchi H, Tsuchiya S. (1993). Stability of liposomes in vitro and their uptake by rat Peyer's patches following oral administration. Pharm Res, 10, 1228-1231.
    • (1993) Pharm Res , vol.10 , pp. 1228-1231
    • Aramaki, Y.1    Tomizawa, H.2    Hara, T.3    Yachi, K.4    Kikuchi, H.5    Tsuchiya, S.6
  • 2
    • 0023056839 scopus 로고
    • Synthesis of an amplifiable reporter RNA for bioassays
    • Chu BC, Kramer FR, Orgel LE. (1986). Synthesis of an amplifiable reporter RNA for bioassays. Nucleic Acids Res, 14, 5591-5603.
    • (1986) Nucleic Acids Res , vol.14 , pp. 5591-5603
    • Chu, B.C.1    Kramer, F.R.2    Orgel, L.E.3
  • 4
    • 0029859532 scopus 로고    scopus 로고
    • Stable formulations of recombinant human growth hormone and interferon-gamma for microencapsulation in biodegradable microspheres
    • Cleland JL, Jones AJ. (1996). Stable formulations of recombinant human growth hormone and interferon-gamma for microencapsulation in biodegradable microspheres. Pharm Res, 13, 1464-1475.
    • (1996) Pharm Res , vol.13 , pp. 1464-1475
    • Cleland, J.L.1    Jones, A.J.2
  • 5
    • 0032584076 scopus 로고    scopus 로고
    • The control of protein release from poly (DL-lactide-co-glycolide) microparticles by variation of external aqueous phase surfactant in the water in oil in water method
    • Coombes AGA, Yeh MK, Lavelle EC, Davis SS. (1998). The control of protein release from poly (DL-lactide-co-glycolide) microparticles by variation of external aqueous phase surfactant in the water in oil in water method. J Control Rel, 52, 311-320.
    • (1998) J Control Rel , vol.52 , pp. 311-320
    • Coombes, A.G.A.1    Yeh, M.K.2    Lavelle, E.C.3    Davis, S.S.4
  • 6
    • 33751253462 scopus 로고    scopus 로고
    • Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach
    • des Rieux A, Fievez V, Garinot M, Schneider YJ, Préat V. (2006). Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach. J Control Release, 116, 1-27.
    • (2006) J Control Release , vol.116 , pp. 1-27
    • Des Rieux, A.1    Fievez, V.2    Garinot, M.3    Schneider, Y.J.4    Préat, V.5
  • 7
    • 9544250398 scopus 로고    scopus 로고
    • Cytokines and antibody subclass associated with protective immunity against blood-stage malaria in mice vaccinated with the C terminus of merozoite surface protein 1 plus a novel adjuvant
    • De Souza JB, Ling IT, Ogun SA, Holder AA, Playfair JH. (1996). Cytokines and antibody subclass associated with protective immunity against blood-stage malaria in mice vaccinated with the C terminus of merozoite surface protein 1 plus a novel adjuvant. Infect Immun, 64, 3532-3536.
    • (1996) Infect Immun , vol.64 , pp. 3532-3536
    • De Souza, J.B.1    Ling, I.T.2    Ogun, S.A.3    Holder, A.A.4    Playfair, J.H.5
  • 8
    • 0021347060 scopus 로고
    • A lavage technique allowing repeated measurement of IgA antibody in mouse intestinal secretions
    • Elson CO, Ealding W, Lefkowitz J. (1984). A lavage technique allowing repeated measurement of IgA antibody in mouse intestinal secretions. J Immunol Methods, 67, 101-108.
    • (1984) J Immunol Methods , vol.67 , pp. 101-108
    • Elson, C.O.1    Ealding, W.2    Lefkowitz, J.3
  • 9
    • 0033866552 scopus 로고    scopus 로고
    • Lectin-mediated bioadhesion: Preparation, stability and caco-2 binding of wheat germ agglutinin-functionalized Poly(D,L-lactic-co-glycolic acid)-microspheres
    • Ertl B, Heigl F, Wirth M, Gabor F. (2000). Lectin-mediated bioadhesion: Preparation, stability and caco-2 binding of wheat germ agglutinin- functionalized Poly(D,L-lactic-co-glycolic acid)-microspheres. J Drug Target, 8, 173-184.
    • (2000) J Drug Target , vol.8 , pp. 173-184
    • Ertl, B.1    Heigl, F.2    Wirth, M.3    Gabor, F.4
  • 10
    • 0030580117 scopus 로고    scopus 로고
    • Peparation of lectin - vicilin nanoparticle conjugates using the carbodiimide coupling technique
    • Ezpeleta I, Irache JM, Stainmesee S, Chabenat C, Gueguen J, and Orecchioni AM. (1996). Peparation of lectin - vicilin nanoparticle conjugates using the carbodiimide coupling technique. Int J Pharm, 142, 227-233.
    • (1996) Int J Pharm , vol.142 , pp. 227-233
    • Ezpeleta, I.1    Irache, J.M.2    Stainmesee, S.3    Chabenat, C.4    Gueguen, J.5    Orecchioni, A.M.6
  • 12
    • 0032033578 scopus 로고    scopus 로고
    • Ulex europaeus 1 lectin targets microsphers to mouse Peyer's patch M cells in vivo
    • Foster N, Clark MA, Jepson MA, Hirst BH. (1998). Ulex europaeus 1 lectin targets microsphers to mouse Peyer's patch M cells in vivo. Vaccine, 16, 536-541.
    • (1998) Vaccine , vol.16 , pp. 536-541
    • Foster, N.1    Clark, M.A.2    Jepson, M.A.3    Hirst, B.H.4
  • 13
    • 33645013856 scopus 로고    scopus 로고
    • Lectinconjugated PEG-PLA nanoparticles: Preparation and brain delivery after intranasal administration
    • Gao X, Tao W, Lu W, Zhang Q, Zhang Y, Jiang X, Fu S. (2006). Lectinconjugated PEG-PLA nanoparticles: Preparation and brain delivery after intranasal administration. Biomaterials, 27, 3482-3490.
    • (2006) Biomaterials , vol.27 , pp. 3482-3490
    • Gao, X.1    Tao, W.2    Lu, W.3    Zhang, Q.4    Zhang, Y.5    Jiang, X.6    Fu, S.7
  • 14
    • 1142273201 scopus 로고    scopus 로고
    • The lectin-cell interaction and its implications to intestinal lectin-mediated drug delivery
    • Gabor F, Bogner E, Weissenboeck A, Wirth M. (2004). The lectin-cell interaction and its implications to intestinal lectin-mediated drug delivery. Adv Drug Deliv Rev, 56, 459-480.
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 459-480
    • Gabor, F.1    Bogner, E.2    Weissenboeck, A.3    Wirth, M.4
  • 15
    • 0031722521 scopus 로고    scopus 로고
    • Lectin-mediated bioadhesion: Binding characteristics of plant lectins on the enterocyte-like cell lines Caco-2, HT-29 and HCT-8
    • Gabor F, Stangl M, Wirth M. (1998). Lectin-mediated bioadhesion: Binding characteristics of plant lectins on the enterocyte-like cell lines Caco-2, HT-29 and HCT-8. J Control Release, 55, 131-142.
    • (1998) J Control Release , vol.55 , pp. 131-142
    • Gabor, F.1    Stangl, M.2    Wirth, M.3
  • 16
    • 0037177459 scopus 로고    scopus 로고
    • Lectin-mediated drug delivery: Binding and uptake of BSA-WGA conjugates using the Caco-2 model
    • Gabor F, Schwarzbauer A, Wirth M. (2002). Lectin-mediated drug delivery: Binding and uptake of BSA-WGA conjugates using the Caco-2 model. Int J Pharm, 237, 227-239.
    • (2002) Int J Pharm , vol.237 , pp. 227-239
    • Gabor, F.1    Schwarzbauer, A.2    Wirth, M.3
  • 17
    • 0025200076 scopus 로고
    • Use of maleimide- thiol coupling chemistry for efficient syntheses of oligonucleotide- enzyme conjugate hybridization probes
    • Ghosh SS, Kao PM, McCue AW, Chappelle HL. (1990). Use of maleimide- thiol coupling chemistry for efficient syntheses of oligonucleotide- enzyme conjugate hybridization probes. Bioconjug Chem, 1, 71-76.
    • (1990) Bioconjug Chem , vol.1 , pp. 71-76
    • Ghosh, S.S.1    Kao, P.M.2    McCue, A.W.3    Chappelle, H.L.4
  • 18
    • 0029841664 scopus 로고    scopus 로고
    • M cells in Peyer's patches of the intestine
    • Gebert A, Rothkötter HJ, Pabst R. (1996). M cells in Peyer's patches of the intestine. Int Rev Cytol, 167, 91-159.
    • (1996) Int Rev Cytol , vol.167 , pp. 91-159
    • Gebert, A.1    Rothkötter, H.J.2    Pabst, R.3
  • 19
    • 0025181840 scopus 로고
    • Zero-length crosslinking procedure with the use of active esters
    • Grabarek Z, Gergely J. (1990). Zero-length crosslinking procedure with the use of active esters. Anal Biochem, 185, 131-135.
    • (1990) Anal Biochem , vol.185 , pp. 131-135
    • Grabarek, Z.1    Gergely, J.2
  • 21
    • 36749076604 scopus 로고    scopus 로고
    • M-cell targeted biodegradable PLGA nanoparticles for oral immunization against hepatitis B
    • Gupta PN, Khatri K, Goyal AK, Mishra N, Vyas SP. (2007). M-cell targeted biodegradable PLGA nanoparticles for oral immunization against hepatitis B. J Drug Target, 15, 701-713.
    • (2007) J Drug Target , vol.15 , pp. 701-713
    • Gupta, P.N.1    Khatri, K.2    Goyal, A.K.3    Mishra, N.4    Vyas, S.P.5
  • 22
    • 33745500127 scopus 로고    scopus 로고
    • Lectin anchored stabilized biodegradable nanoparticles for oral immunization 1. Development and in vitro evaluation
    • Gupta PN, Mahor S, Rawat A, Khatri K, Goyal A, Vyas SP. (2006). Lectin anchored stabilized biodegradable nanoparticles for oral immunization 1. Development and in vitro evaluation. Int J Pharm, 318, 163-173.
    • (2006) Int J Pharm , vol.318 , pp. 163-173
    • Gupta, P.N.1    Mahor, S.2    Rawat, A.3    Khatri, K.4    Goyal, A.5    Vyas, S.P.6
  • 23
    • 0021711026 scopus 로고
    • Common conditions for high-performance liquid chromatographic microdetermination of aldoses, hexosamines, and sialic acids in glycoproteins
    • Honda S, Suzuki S. (1984). Common conditions for high-performance liquid chromatographic microdetermination of aldoses, hexosamines, and sialic acids in glycoproteins. Anal Biochem, 142, 167-174.
    • (1984) Anal Biochem , vol.142 , pp. 167-174
    • Honda, S.1    Suzuki, S.2
  • 24
    • 33646139149 scopus 로고    scopus 로고
    • Strong systemic and mucosal immune responses to surface-modified PLGA microspheres containing recombinant hepatitis B antigen administered intranasally
    • Jaganathan KS, Vyas SP. (2006). Strong systemic and mucosal immune responses to surface-modified PLGA microspheres containing recombinant hepatitis B antigen administered intranasally. Vaccine, 24, 4201-4211.
    • (2006) Vaccine , vol.24 , pp. 4201-4211
    • Jaganathan, K.S.1    Vyas, S.P.2
  • 25
    • 5644235479 scopus 로고    scopus 로고
    • Development of a single-dose stabilized poly(D,L-lactic-coglycolic acid) microspheres-based vaccine against hepatitis B
    • Jaganathan KS, Singh P, Prabakaran D, Mishra V, Vyas SP. (2004). Development of a single-dose stabilized poly(D,L-lactic-coglycolic acid) microspheres-based vaccine against hepatitis B. J Pharm Pharmacol, 56, 1243-1250.
    • (2004) J Pharm Pharmacol , vol.56 , pp. 1243-1250
    • Jaganathan, K.S.1    Singh, P.2    Prabakaran, D.3    Mishra, V.4    Vyas, S.P.5
  • 26
    • 24744448887 scopus 로고    scopus 로고
    • Mannosylated niosomes as adjuvant-carrier system for oral genetic immunization against hepatitis B
    • Jain S, Singh P, Mishra V, Vyas SP. (2005). Mannosylated niosomes as adjuvant-carrier system for oral genetic immunization against hepatitis B. Immunol Lett, 101, 41-49.
    • (2005) Immunol Lett , vol.101 , pp. 41-49
    • Jain, S.1    Singh, P.2    Mishra, V.3    Vyas, S.P.4
  • 28
    • 0022427984 scopus 로고
    • Tomato lectin resists digestion in the mammalian alimentary canal and binds to intestinal villi without deleterious effects
    • Kilpatrick DC, Pusztai A, Grant G, Graham C, Ewen SW. (1985). Tomato lectin resists digestion in the mammalian alimentary canal and binds to intestinal villi without deleterious effects. FEBS Lett, 185, 299-305.
    • (1985) FEBS Lett , vol.185 , pp. 299-305
    • Kilpatrick, D.C.1    Pusztai, A.2    Grant, G.3    Graham, C.4    Ewen, S.W.5
  • 30
    • 2942724579 scopus 로고    scopus 로고
    • Immunological implications of the use of plant lectins for drug and vaccine targeting to the gastrointestinal tract
    • Lavelle EC, Grant G, Pfuller U, O'Hagan DT. (2004). Immunological implications of the use of plant lectins for drug and vaccine targeting to the gastrointestinal tract. J Drug Target, 12, 89-95.
    • (2004) J Drug Target , vol.12 , pp. 89-95
    • Lavelle, E.C.1    Grant, G.2    Pfuller, U.3    O'Hagan, D.T.4
  • 31
    • 0024836302 scopus 로고
    • Penetration and enzymatic barriers to peptide and protein absorption
    • Lee VHL, Yamamoto A. (1989). Penetration and enzymatic barriers to peptide and protein absorption. Adv Drug Deliv Rev, 4, 171-207.
    • (1989) Adv Drug Deliv Rev , vol.4 , pp. 171-207
    • Lee, V.H.L.1    Yamamoto, A.2
  • 33
    • 0022555853 scopus 로고
    • Lectins as molecules and as tools
    • Lis H, Sharon N. (1986). Lectins as molecules and as tools. Annu Rev Biochem, 55, 35-67.
    • (1986) Annu Rev Biochem , vol.55 , pp. 35-67
    • Lis, H.1    Sharon, N.2
  • 34
    • 0035857704 scopus 로고    scopus 로고
    • Covalent coupling of asparagus pea and tomato lectins to poly(lactide) microspheres
    • Montisci MJ, Giovannuci G, Duchêne D, Ponchel G. (2001a). Covalent coupling of asparagus pea and tomato lectins to poly(lactide) microspheres. Int J Pharm, 215, 153-161.
    • (2001) Int J Pharm , vol.215 , pp. 153-161
    • Montisci, M.J.1    Giovannuci, G.2    Duchêne, D.3    Ponchel, G.4
  • 35
    • 0034874194 scopus 로고    scopus 로고
    • Gastrointestinal transit and mucoadhesion of colloidal suspensions of Lycopersicon esculentum L. and Lotus tetragonolobus lectin-PLA microsphere conjugates in rats
    • Montisci MJ, Dembri A, Giovannuci G, Chacun H, Duchêne D, Ponchel G. (2001b). Gastrointestinal transit and mucoadhesion of colloidal suspensions of Lycopersicon esculentum L. and Lotus tetragonolobus lectin-PLA microsphere conjugates in rats. Pharm Res, 18, 829-837.
    • (2001) Pharm Res , vol.18 , pp. 829-837
    • Montisci, M.J.1    Dembri, A.2    Giovannuci, G.3    Chacun, H.4    Duchêne, D.5    Ponchel, G.6
  • 36
    • 0026329229 scopus 로고
    • Endogenous tumor necrosis factor, interleukin-6, and gamma interferon levels during Listeria monocytogenes infection in mice
    • Nakane A, Numata A, Minagawa T. (1992). Endogenous tumor necrosis factor, interleukin-6, and gamma interferon levels during Listeria monocytogenes infection in mice. Infect Immun, 60, 523-528.
    • (1992) Infect Immun , vol.60 , pp. 523-528
    • Nakane, A.1    Numata, A.2    Minagawa, T.3
  • 38
    • 0032403502 scopus 로고    scopus 로고
    • Microparticles and polymers for the mucosal delivery of vaccines
    • O'Hagan DT. (1998). Microparticles and polymers for the mucosal delivery of vaccines. Adv Drug Del Rev, 34, 305-320.
    • (1998) Adv Drug Del Rev , vol.34 , pp. 305-320
    • O'Hagan, D.T.1
  • 40
    • 0016200121 scopus 로고
    • Specificity of purified hemagglutinin (lectin) from Lotus tetragonolobus
    • Pereira ME, Kabat EA. (1974). Specificity of purified hemagglutinin (lectin) from Lotus tetragonolobus. Biochemistry, 13, 3184-3192.
    • (1974) Biochemistry , vol.13 , pp. 3184-3192
    • Pereira, M.E.1    Kabat, E.A.2
  • 41
    • 0034601198 scopus 로고    scopus 로고
    • Liposome-entrapped plasmid DNA: Characterisation studies
    • Perrie Y, Gregoriadis G. (2000). Liposome-entrapped plasmid DNA: Characterisation studies. Biochim Biophys Acta, 1475, 125-132.
    • (2000) Biochim Biophys Acta , vol.1475 , pp. 125-132
    • Perrie, Y.1    Gregoriadis, G.2
  • 42
    • 0032403467 scopus 로고    scopus 로고
    • Specific and non-specific bioadhesive particulate systems for oral delivery to the gastrointestinal tract
    • Ponchel G, Irache J. (1998). Specific and non-specific bioadhesive particulate systems for oral delivery to the gastrointestinal tract. Adv Drug Deliv Rev, 34, 191-219.
    • (1998) Adv Drug Deliv Rev , vol.34 , pp. 191-219
    • Ponchel, G.1    Irache, J.2
  • 43
    • 0032711921 scopus 로고    scopus 로고
    • Lectin-mediated transport of nanoparticles across Caco-2 and OK cells
    • Russell-Jones GJ, Veitch H, Arthur L. (1999). Lectin-mediated transport of nanoparticles across Caco-2 and OK cells. Int J Pharm, 190, 165-174.
    • (1999) Int J Pharm , vol.190 , pp. 165-174
    • Russell-Jones, G.J.1    Veitch, H.2    Arthur, L.3
  • 46
    • 0037130209 scopus 로고    scopus 로고
    • Residual polyvinyl alcohol associated with poly (D,L-lactide-co- glycolide) nanoparticles affects their physical properties and cellular uptake
    • Sahoo SK, Panyam J, Prabha S, Labhasetwar V. (2002). Residual polyvinyl alcohol associated with poly (D,L-lactide-co-glycolide) nanoparticles affects their physical properties and cellular uptake. J Control Release, 82, 105-114.
    • (2002) J Control Release , vol.82 , pp. 105-114
    • Sahoo, S.K.1    Panyam, J.2    Prabha, S.3    Labhasetwar, V.4
  • 47
    • 0033043628 scopus 로고    scopus 로고
    • The acidic microclimate in poly(lactide-co-glycolide) microspheres stabilizes camptothecins
    • Shenderova A, Burke TG, Schwendeman SP. (1999). The acidic microclimate in poly(lactide-co-glycolide) microspheres stabilizes camptothecins. Pharm Res, 16, 241-248.
    • (1999) Pharm Res , vol.16 , pp. 241-248
    • Shenderova, A.1    Burke, T.G.2    Schwendeman, S.P.3
  • 48
    • 0036285313 scopus 로고    scopus 로고
    • Pharmaceutical and immunological evaluation of a single-shot hepatitis B vaccine formulated with PLGA microspheres
    • Shi L, Caulfield MJ, Chern RT, Wilson RA, Sanyal G, Volkin DB. (2002). Pharmaceutical and immunological evaluation of a single-shot hepatitis B vaccine formulated with PLGA microspheres. J Pharm Sci, 91, 1019-1035.
    • (2002) J Pharm Sci , vol.91 , pp. 1019-1035
    • Shi, L.1    Caulfield, M.J.2    Chern, R.T.3    Wilson, R.A.4    Sanyal, G.5    Volkin, D.B.6
  • 49
    • 53549127573 scopus 로고    scopus 로고
    • Oral immunization against hepatitis B using bile salt stabilized vesicles (bilosomes)
    • Shukla A, Khatri K, Gupta PN, Goyal AK, Mehta A, Vyas SP. (2008). Oral immunization against hepatitis B using bile salt stabilized vesicles (bilosomes). J Pharm Pharm Sci, 11, 59-66.
    • (2008) J Pharm Pharm Sci , vol.11 , pp. 59-66
    • Shukla, A.1    Khatri, K.2    Gupta, P.N.3    Goyal, A.K.4    Mehta, A.5    Vyas, S.P.6
  • 50
    • 0030928864 scopus 로고    scopus 로고
    • Controlled release microparticles as a single dose hepatitis B vaccine: Evaluation of immunogenicity in mice
    • Singh M, Li XM, McGee JP, Zamb T, Koff W, Wang CY, O'Hagan DT. (1997). Controlled release microparticles as a single dose hepatitis B vaccine: Evaluation of immunogenicity in mice. Vaccine, 15, 475-481.
    • (1997) Vaccine , vol.15 , pp. 475-481
    • Singh, M.1    Li, X.M.2    McGee, J.P.3    Zamb, T.4    Koff, W.5    Wang, C.Y.6    O'Hagan, D.T.7
  • 51
    • 2942608191 scopus 로고    scopus 로고
    • Cholera toxin B subunit conjugated bile salt stabilized vesicles (bilosomes) for oral immunization
    • Singh P, Prabakaran D, Jain S, Mishra V, Jaganathan KS, Vyas SP. (2004). Cholera toxin B subunit conjugated bile salt stabilized vesicles (bilosomes) for oral immunization. Int J Pharm, 278, 379-390.
    • (2004) Int J Pharm , vol.278 , pp. 379-390
    • Singh, P.1    Prabakaran, D.2    Jain, S.3    Mishra, V.4    Jaganathan, K.S.5    Vyas, S.P.6
  • 52
    • 0022512416 scopus 로고
    • Enhancement by N-hydroxysulfosuccinimide of water-soluble carbodiimide-mediated coupling reactions
    • Staros JV, Wright RW, Swingle DM. (1986). Enhancement by N-hydroxysulfosuccinimide of water-soluble carbodiimide-mediated coupling reactions. Anal Biochem, 156, 220-222.
    • (1986) Anal Biochem , vol.156 , pp. 220-222
    • Staros, J.V.1    Wright, R.W.2    Swingle, D.M.3
  • 53
    • 0031918253 scopus 로고    scopus 로고
    • Stealth PLAPEG nanoparticles as protein carriers for nasal administration
    • Tobío M, Gref R, Sánchez A, Langer R, Alonso MJ. (1998). Stealth PLAPEG nanoparticles as protein carriers for nasal administration. Pharm Res, 15, 270-275.
    • (1998) Pharm Res , vol.15 , pp. 270-275
    • Tobío, M.1    Gref, R.2    Sánchez, A.3    Langer, R.4    Alonso, M.J.5
  • 54
    • 0034255536 scopus 로고    scopus 로고
    • Polysaccharide coated liposomes for oral immunization-development and characterization
    • Venkatesan N, Vyas SP. (2000). Polysaccharide coated liposomes for oral immunization-development and characterization. Int J Pharm, 203, 169-177.
    • (2000) Int J Pharm , vol.203 , pp. 169-177
    • Venkatesan, N.1    Vyas, S.P.2
  • 55
    • 0034944279 scopus 로고    scopus 로고
    • Preparation, characterization and in-vitro antimicrobial activity of metronidazole bearing lectinized liposomes for intra peridontal pocket delivery
    • Vyas SP, Sihorkar V, Dubey PK. (2001). Preparation, characterization and in-vitro antimicrobial activity of metronidazole bearing lectinized liposomes for intra peridontal pocket delivery. Pharmazie, 56, 554-560.
    • (2001) Pharmazie , vol.56 , pp. 554-560
    • Vyas, S.P.1    Sihorkar, V.2    Dubey, P.K.3
  • 57
    • 0346186975 scopus 로고    scopus 로고
    • Adjuvant synergy in the response to hepatitis B vaccines
    • Wang S, Liu X, Caulfield MJ. (2003). Adjuvant synergy in the response to hepatitis B vaccines. Vaccine, 21, 4297-4306.
    • (2003) Vaccine , vol.21 , pp. 4297-4306
    • Wang, S.1    Liu, X.2    Caulfield, M.J.3
  • 58
    • 4644292567 scopus 로고    scopus 로고
    • WGA-grafted PLGAnanospheres: Preparation and association with Caco-2 single cells
    • Weissenböck A, Wirth M, Gabor F. (2004). WGA-grafted PLGAnanospheres: Preparation and association with Caco-2 single cells. J Control Release, 99, 383-392.
    • (2004) J Control Release , vol.99 , pp. 383-392
    • Weissenböck, A.1    Wirth, M.2    Gabor, F.3
  • 59
    • 0033986610 scopus 로고    scopus 로고
    • Stabilization of proteins encapsulated in injectable poly (lactide- co-glycolide)
    • Zhu G, Mallery SR, Schwendeman SP. (2000). Stabilization of proteins encapsulated in injectable poly (lactide- co-glycolide). Nat Biotechnol, 18, 52-57.
    • (2000) Nat Biotechnol , vol.18 , pp. 52-57
    • Zhu, G.1    Mallery, S.R.2    Schwendeman, S.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.